SHIMIZU Toshio 清水俊夫

Researcher Number	00110750
Other IDs
Affiliation (based on the past Project Information) *help	2008: 弘前大学, 大学院・理工学研究科, 教授 2002 – 2004: 弘前大学, 理工学部, 教授 1988 – 1989: 弘前大学, 教養部, 助教授
Review Section/Research Field	Principal Investigator Biological Sciences / Biophysics Except Principal Investigator 化学工学 / Neurology
Keywords	Principal Investigator 膜貫通トポロジー / 膜貫通タンパク質 / 膜貫通トポロジー進化 / 遺伝子内重複 / コンセンサス予測法 / コンセンサス膜貫通トポロジー予測 / クラスタリング / 膜貫通トポロジー類似度 / ゲノムスケール解析 / シグナル配列 … More / GPCR / internal gene duplication / transmembrane topology evolution / binary topology pattern / proteome-wide / consensus prediction / transmembrane topology / transmembrane protein / 原核生物ゲノム / トポロジー予測法 / Gタンパク質共役型受容体 / Binary Topology Pattern / シグナルペプチド / 機能分類・同定 / バイナリー・トポロジー・パターン / 網羅的分類 / 構造・機能 / 膜貫通値ポロジー / 膜貫通トポロジー類以性 / 網羅的機能分類・同定 / 機能・構造の網羅的分類・同定 / 膜貫通トポロジー予測 / シグナルペプチド予測 / 膜貫通トポロジーの進化 / 網羅的機能予測 / 予測性能評価 / 膜貫通トポロジー予測法 … More Except Principal Investigator Dispersion relation / resonance angle / reflectivity curve / adsorption isotherm / Metal thin film / Polymer or protein / Laser excitation / Surface plasmon / パソコンによる自動測定化 / イオン性界面活性剤 / 吸着層の厚さ / パソコン制御 / プラズモン・ポラリトン / 吸着等温線 / 共鳴吸収の理論 / 全自動測定 / レ-ザ-光 / 表面吸着 / 生体高分子 / 表面プラズモン共鳴吸収 / transporter / treatment / receptor / ion channel / CYP / polymorohism / gene / Epilepsy / 個別化治療 / てんかん / 脳神経疾愚 / 脳神経学 / 遺伝子 / 脳神経疾患 / 神経科学 / シグナル伝達 / ゲノム Less

膜貫通トポロジー情報を利用した膜貫通タンパク質機能の網羅的分類・予測Principal Investigator
- Principal Investigator
  
  清水俊夫
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Analysis of molecular biology of epilepsy
- Principal Investigator
  
  KANEKO Sunao
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
トポロジー類似性にもとづく膜貫通タンパク質機能の分類・予測Principal Investigator
- Principal Investigator
  
  清水俊夫
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
膜貫通タンパク質構造・機能のプロテオーム解析Principal Investigator
- Principal Investigator
  
  清水俊夫
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Genome-wide classification and identification of transmembrane protein structure and functionPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Toshio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Hirosaki University
Development of New Apparatus for Measurements of Resonant Excitation of Surface Plasmons by Laser from Layers of Polymers or Proteins Adsorbed on a Metal Thin Film
- Principal Investigator
  
  HAMAUZU Yoshihiro, 小松弘昌
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  化学工学
- Research Institution
  Numazu College of Technology

All 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Sequence Sehection for Multiple Alignments of Transmembrane Proteins2009
- Author(s)
  Nishio T, Ohta T, Kaneko S, and Shimizu T.
- Journal Title
  
  Information 12
  
  Pages: 235-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Sequence Selection for Multiple Alignments of Transmembrane Proteins2009
- Author(s)
  Nishio T, Ohta T, Kaneko S, and Shimizu T.
- Journal Title
  
  Information 12
  
  Pages: 235-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Performance Evaluation of Loop-Structured-Computer by Applying Pairwise Seauence Alignment2008
- Author(s)
  Ichijo K, Kikuchi N, Yoshioka Y, and Shimizu T.
- Journal Title
  
  Information 11
  
  Pages: 351-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] How to obtain multiple alignments in which transmembrane segment regions are well aligned without inserted2006
- Author(s)
  Kimura T, Ohta T, Nishio T, Shimizu T
- Journal Title
  
  Chem-Bio Informatics Journal, under revision. (in press)
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Analysis of tandem repeats found in 44 prokaryotic genomes.2006
- Author(s)
  Mizuta S, Munakata H, Aimaiti A, Oya I., Oosawa K., Shimizu T.
- Journal Title
  
  In Silico Bio 16
  
  Pages: 147-159
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Analysis of tandem repeats found in 44 prokaryotic genomes2006
- Author(s)
  Mizuta S, Munakata H, Aimaiti A, Oya I, Oosawa K, Shimizu T
- Journal Title
  
  In Silico Biology (in press) (accepted.)
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Model analysis of surfactant-polymer interaction as cooperative ligand2005
- Author(s)
  T.Nishio, T.Shimizu
- Journal Title
  
  Biophysical Chemistry (in press)
- Data Source
  KAKENHI-PROJECT-16014202
[Journal Article] How accurately G-protein-coupled receptors can be discriminated as 7-tms TM protein sequences from others?2005
- Author(s)
  Inoue Y, Yamazaki Y, Shimizu T
- Journal Title
  
  Biochem.Biophys.Res.Commun 338
  
  Pages: 1542-1546
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] A proteome-wide analysis of domain architectures of prokaryotic single-spanning transmembrane proteins2005
- Author(s)
  Arai M, Fukushi T, Satake M, Shimizu T
- Journal Title
  
  Comput.Biol.Chem 29
  
  Pages: 379-387
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Model analysis of surfactant-polymer interaction as cooperative ligand binding to linear lattice2005
- Author(s)
  Nishio T, Shimizu T
- Journal Title
  
  Biophysical Chemistry 117
  
  Pages: 19-25
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] ConPred_elite : a highly reliable approach to transmembrane topology prediction2004
- Author(s)
  J.-X.Xia, M.Ikeda, T.Shimizu
- Journal Title
  
  Computational Biology and Chemistry 28
  
  Pages: 51-60
- Data Source
  KAKENHI-PROJECT-16014202
[Journal Article] Proteome-wide functional classification and identification of Prokaryotic transmembrane proteins by transmembrane topology similarity comparison.2004
- Author(s)
  Arai M, Shimizu T, et al.
- Journal Title
  
  Protein Sci 13
  
  Pages: 2170-2183
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] ConPred II : a consensus prediction method for obtaining transmembrane topology models with high reliability2004
- Author(s)
  M.Arai, H.Mitsuke, M.Ikeda, J.-X.Xia, T.Kikuchi, M.Satake, T.Shimizu
- Journal Title
  
  Nucleic Acids Research 32,Web Server Issue
- Data Source
  KAKENHI-PROJECT-16014202
[Journal Article] Evaluation of the color-coding method for searching tandem repeats in2004
- Author(s)
  S.Mizuta, H.Munakata, A.Aimaiti, K.Oosawa, T.Shimizu
- Journal Title
  
  Chem-Bio Informatics Journal 4
  
  Pages: 133-141
- Data Source
  KAKENHI-PROJECT-16014202
[Journal Article] Internal gene duplication in the evolution of prokaryotic transmembrane proteins.2004
- Author(s)
  Shimizu T, et al.
- Journal Title
  
  J Mol Biol 339
  
  Pages: 1-15
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Proteome-wide functional classification and identification of prokaryotic2004
- Author(s)
  M.Arai, K.Okumura, M.Satake, T.Shimizu
- Journal Title
  
  Protein Science 13
  
  Pages: 2170-2183
- Data Source
  KAKENHI-PROJECT-16014202
[Journal Article] Evaluation of the color-coding method for searching tanden repeats in prokaryotic genomes.2004
- Author(s)
  Mizuta S, Shimizu T, et al.
- Journal Title
  
  Chem-Bio Informatics J 4/4
  
  Pages: 133-141
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] ConPred II : a consensus prediction method for obtaining transmembrane topology models with high reliability.2004
- Author(s)
  Arai M, Shimizu T, et al.
- Journal Title
  
  Nucleic Acids Res 32
  
  Pages: 390-393
- Data Source
  KAKENHI-PROJECT-16109006
[Journal Article] Proteome-wide classification and identification of mammalian-type GPCRs by binary topology pattern2004
- Author(s)
  Y.Inoue, M.Ikeda, T.Shimizu
- Journal Title
  
  Computational Biology and Chemistry 28
  
  Pages: 39-49
- Data Source
  KAKENHI-PROJECT-16014202
[Journal Article] Internal Gene Duplication in the Evolution of Prokaryotic Transmembrane2004
- Author(s)
  T.Shimizu, H.Mitsuke, K.Noto, M.Arai
- Journal Title
  
  J.Molecular Biology 339巻
  
  Pages: 1-15
- Data Source
  KAKENHI-PROJECT-16014202
[Presentation] てんかん責任遺伝子変異データベースー.2008
- Author(s)
  吉田秀一, 金井数明, 小島俊男, 山崎祥拓, 清水俊夫, 兼子直, Epilepsy Genetic Study Group Japan.
- Organizer
  第35回東北てんかん談話会
- Place of Presentation
  盛岡
- Year and Date
  2008-03-08
- Data Source
  KAKENHI-PROJECT-16109006
[Presentation] ポア形成領域以外に生じたSCN1Aミスセンス変異のアミノ酸置換が表現型に与える影響.2007
- Author(s)
  金井数明, 廣瀬伸一, 小国弘量, 福間五龍, 桑原聡, 吉田秀一, 澤井摂, 岩佐博人, 清水俊夫, 伊藤正利, 服部孝道, 兼子直.
- Organizer
  第41回日本てんかん学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-16109006

1. SATOH Kei (20125438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. WAKABAYASHI Koichi (50240768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KOMATSU Hiromasa (10043142)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KANEKO Sunao (40106852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. WADA Kazumaru (60241486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OKADA Motohiro (10281916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YASUI-FURUKORI Norio (20333734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOJIMA Toshio (00311340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. UENO Shinya (00312158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUKUSAWA Masashi (10231557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAGAWA Kazuko (20284747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIROSE Shinichi (60248515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. YAMAKAWA Kazuhiro (30241235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TSUJI Shoji (70150612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KUWANO Ryozo (20111734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ARAKI Kimi (90211705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HAMAUZU Yoshihiro (50124037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HASUMI Fumihiko (90164805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MISAKI Hideo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FUJII Tadayo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMIZU Toshio 清水 俊夫

Research Projects

Research Products

Co-Researchers

膜貫通トポロジー情報を利用した膜貫通タンパク質機能の網羅的分類・予測Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular biology of epilepsy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

トポロジー類似性にもとづく膜貫通タンパク質機能の分類・予測Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膜貫通タンパク質構造・機能のプロテオーム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome-wide classification and identification of transmembrane protein structure and functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of New Apparatus for Measurements of Resonant Excitation of Surface Plasmons by Laser from Layers of Polymers or Proteins Adsorbed on a Metal Thin Film

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sequence Sehection for Multiple Alignments of Transmembrane Proteins2009

Author(s)

Journal Title

Data Source

[Journal Article] Sequence Selection for Multiple Alignments of Transmembrane Proteins2009

Author(s)

Journal Title

Data Source

[Journal Article] Performance Evaluation of Loop-Structured-Computer by Applying Pairwise Seauence Alignment2008

Author(s)

Journal Title

Data Source

[Journal Article] How to obtain multiple alignments in which transmembrane segment regions are well aligned without inserted2006

Author(s)

Journal Title

Data Source

[Journal Article] Analysis of tandem repeats found in 44 prokaryotic genomes.2006

Author(s)

Journal Title

Data Source

[Journal Article] Analysis of tandem repeats found in 44 prokaryotic genomes2006

Author(s)

Journal Title

Data Source

[Journal Article] Model analysis of surfactant-polymer interaction as cooperative ligand2005

Author(s)

Journal Title

Data Source

[Journal Article] How accurately G-protein-coupled receptors can be discriminated as 7-tms TM protein sequences from others?2005

Author(s)

Journal Title

Data Source

[Journal Article] A proteome-wide analysis of domain architectures of prokaryotic single-spanning transmembrane proteins2005

Author(s)

Journal Title

Data Source

[Journal Article] Model analysis of surfactant-polymer interaction as cooperative ligand binding to linear lattice2005

Author(s)

Journal Title

Data Source

SHIMIZU Toshio 清水俊夫