YASUHARA Masato 安原眞人

… Alternative Names

安原眞人ヤスハラマサト

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Researcher Number	00127151
Other IDs
Affiliation (Current)	2025: 帝京大学, 薬学部, 特任教授
Affiliation (based on the past Project Information) *help	2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 2009 – 2013: Tokyo Medical and Dental University, 医学部附属病院, 教授 2011: 東京医科歯科大学, 医学部・附属病院, 教授 2000: Tokyo Medical and Dental University, Faculty of Medicine, Professor, 医学部, 教授 1999 – 2000: 東京医科歯科大学, 医学部・附属病院, 教授 … More 1997 – 1998: 東京医科歯科大学, 医学部, 教授 1996: 東京医科歯科大学, 医学部付属病院, 教授 1995: Tokyo Medical & Dental Univ., Med., Prof., 医学部, 教授 1994: 東京医科歯科大学, 医学部附属病院, 教授 1991 – 1994: 京都大学, 医学部, 助教授 1989: Kyoto Univ., Faculty of Med., Lecturer, 医学部, 講師 1986: Kyoto University, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 医薬分子機能学 / Physical pharmacy / Medical pharmacy Except Principal Investigator Physical pharmacy / 応用薬理学・医療系薬学
Keywords	Principal Investigator pharmacokinetics / 薬物体内動態 / ポピュレーション解析 / ペプチド性医薬品 / ペンタミジン / ニューキノロン系抗菌薬 / N-acetylprocainamide / cefoperazone / losartan / acute renal failure … More / drug metabolism / organ correlation / N-アセチルプロカインアミド / セフォペラゾン / ロサルタン / 急性腎不全 / 薬物代謝 / 臓器相関 / renal excretion / population analysis / cyclosporin A / vancomycin / peptide drugs / 腎機能障害 / 腎排泄 / 体内動態 / シクロスポリン / バンコマイシン / Living-related donor liver transplantation / Hepatic extraction / Pharmacodynamics / Pharmacokinetics / Tacrolimus / Population analysis / Immunosuppressive agent / 肝疾患 / 肝抽出率 / 生体肝移植 / 薬力学 / タクロリムス / 免疫抑制剤 / Receptor / C1earance / Isolated kidney perfusion / Granulocyte-colony stimulating factor / Brain natriuretic Peptide / Atrial natriuretic peptide / Natriuretic peptide / Peptide drugs / 培養腎尿細管上皮細胞 / レセプター / クリアランス / 腎潅流 / 顆粒球コロニー形成刺激因子 / BNP / ANP / ナトリウム利尿ペプチド / 薬物間相互作用 / シメチジン / モキシフロキサシン / オランザピン / 血糖値上昇 / pharmacodynamics / olanzapine / moxifloxacin / pentamidine / hyperglycemia / dysglycemia / インスリン / 間モデル / ファーマコキネテックス / 間接モデル / ファーマコキネティクス / ファーマコダイナミックス / ファーマコキネティックス / 血糖値異常 / シベンゾリン / ガチフロキサシン … More Except Principal Investigator 薬物体内動態 / population pharmacokinetics / 投与設計 / Population pharmacokinetics / P-glycoprotein / Gene transfection / 分子機構 / 体内動態 / レセプター / 生理活性物質 / 医薬品開発 / 薬物治療 / Renal dysfunction / Hyperthyroidism / Arrhythmias / Disease state models / Design of dosage regimen / Pharmacodynamics / Pharmacokinetics / Antiarrhythmics / エフェクトコンパートメントモデル / 心電図 / 心拍数依存性 / 甲状腺機能亢進 / 病態 / 薬理効果 / 抗不整脈剤 / プロプラノロ-ル / アジマリン / バイオアベイラビリティ- / 初回通過効果 / 腎疾患 / 甲状腺機能亢進症 / 不整脈 / 病態モデル動物 / 薬物投与計画 / pharmacodynamics / pharmacokinetics / 抗不整脈薬 / digoxin / carbamazepine; phenytoin / valproic acid / drug dosage regimen / therapeutic drug monitoring / VALPROIC ACID / THEOPHYLLINE / THERAPEUTIC DRUG MONITORING / ベイズ理論 / POPULATION / PHARMACOKINETICS / テオフィリン / ジゴキシン / フェニトイン / カルバマゼピン / バルプロ酸 / 薬物治療モニタリング / Dosage regimen / Isolated perfused kidney / Renal excretion / モ-メント解析 / 刷子縁膜 / 有機アニオン輸送系 / 薬物投与設計 / gene transfection / 経細胞輸送 / 有機カチオン輸送系 / 摘出腎潅流 / 腎排泄 / ドラッグデリバリーシステム / Drug Delivery System Less

Kinetics of drug-induced dysglycemiaPrincipal Investigator
- Principal Investigator
  
  YASUHARA Masato
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo Medical and Dental University
Kinetics of Dysglycemia Induced by New Quinolone AntibioticsPrincipal Investigator
- Principal Investigator
  
  YASUHARA Masato
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo Medical and Dental University
Research on Organ Correlation of Drug Metabolic Activities by Gene TechnologyPrincipal Investigator
- Principal Investigator
  
  YASUHARA Masato
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tokyo Medical and Dental University
Kinetics of Renal Disposition and Action of Bioactive PeptidesPrincipal Investigator
- Principal Investigator
  
  YASUHARA Masato
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tokyo Medical and Dental University
ドラッグデリバリーの空間的・時間的制御
- Principal Investigator
  
  橋田充
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
ドラッグデリバリーの空間的・時間的制御
- Principal Investigator
  
  橋田満
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Population Analysis of Pharmacokinetics and Pharmacodynamics of an Immunosuppresive AgentPrincipal Investigator
- Principal Investigator
  
  YASUHARA Masato
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo Medical and Dental University
  Kyoto University
Kinetics of Rena1 Dispositon and Pharmacological Effect of PeptidesPrincipal Investigator
- Principal Investigator
  
  YASUHARA Masato
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Scientific Basis of Drug Disposition in the Kidney and its Application to Clinical Dosage Regimens.
- Principal Investigator
  
  HORI Ryohei
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Pharmacokinetics and Pharmacodynamics of Antiarrhythmic Drugs in Disease State
- Principal Investigator
  
  HORI Ryohei
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
Application of population pharmacokinetics to the individualization of drug dosage regimen.
- Principal Investigator
  
  HORI Ryohei
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto University

All 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Other

[Journal Article] Pharmacokinetic–Pharmacodynamic Analysis of Sunitinib-Induced Thrombocytopenia in Japanese Patients with Renal Cell Carcinoma2015
- Author(s)
  M. Nagata, Y. Ishiwata, Y. Takahashi, H. Takahashi, K. Saito, Y. Fujii, K. Kihara, M. Yasuhara
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 3 Pages: 402-410
- DOI
  10.1248/bpb.b14-00636
- NAID
  130004872283
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590180
[Journal Article] Effects of Moxifloxacin on Serum Glucose Concentrations in Rats2013
- Author(s)
  Y. Ishiwata, Y. Takahashi, M. Nagata, M. Yasuhara
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 4 Pages: 686-690
- DOI
  10.1248/bpb.b12-00930
- NAID
  130003361398
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590180
[Journal Article] Pharmacodynamics of cibenzoline-induced hypoglycemia in rats2011
- Author(s)
  Y. Takahashi, Y. Ishiwata, Y. Kojima, M. Yasuhara
- Journal Title
  
  Drug Metab. Pharmacokin.
  
  Volume: 36 Pages: 242-247
- NAID
  130004463184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590151
[Journal Article] Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts2010
- Author(s)
  A. Hoshino, T. Iimura, S. Ueha, S. Hanada, Y. Maruoka, M. Mayahara, K. Suzuki, T. Imai, M. Ito, Y. Manome, M. Yasuhara, T. Kirino, A. Yamaguchi, K. Matsuhima, K. Yamamoto
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 285 Pages: 28826-28837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590151
[Journal Article] Gatifloxacin-induced histamine release and hyperglycemia in rats2010
- Author(s)
  Y. Ishiwata, M. Yasuhara
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 645 Pages: 192-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590151
[Journal Article] Concurrent administration of intravenous systemic and intravitreal methotrexate for intraocular lymphoma with central nervous system involvement2010
- Author(s)
  Y. Nakauchi, H. Takase, S. Sugita, M. Mochizuki, S. Shibata, Y. Ishiwata, Y. Shibuya, M. Yasuhara, O. Miura, A. Arai
- Journal Title
  
  Int. J. Hematol.
  
  Volume: 92 Pages: 179-185
- NAID
  10026512401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590151
[Journal Article] Pharmacokinetic monitoring is still required for intravenous busulfan in SCT for small children2010
- Author(s)
  M. Nagasawa, N. Mitsuiki, T. Ono, M. Takagi, H. Oda, M. Yasuhara, S. Mizutani
- Journal Title
  
  Int. J. Hematol.
  
  Volume: 91 Pages: 728-730
- NAID
  10026402408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590151
[Presentation] 難病治療への挑戦2014
- Author(s)
  安原眞人
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本（ホテル日航熊本）
- Data Source
  KAKENHI-PROJECT-24590180
[Presentation] 薬物動態と薬理効果の速度論的研究2012
- Author(s)
  安原眞人
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-24590180
[Presentation] Pharma-codynamics of gatifloxacininduced dysglycemia in rats2010
- Author(s)
  M. Yasuhara, Y. Ishiwata
- Organizer
  12th Buffalo Pharmaceutics Symposium
- Place of Presentation
  Buffalo, New York
- Data Source
  KAKENHI-PROJECT-21590151
[Presentation] Effects of experimental renal failure on the pharmacokinetics of cibenzoline in rats2009
- Author(s)
  Masato Yasuhara
- Organizer
  日本薬物動態学会第24年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21590151
[Presentation] ラットにおけるオランザピン単回投与による血糖値上昇のメカニズム
- Author(s)
  中島真由美、石渡泰芳、永田将司、高橋弘充、根岸健一、安原眞人
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590180
[]

1. TANIGAWARA Yusuke (30179832)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HORI Ryohei (40001036)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 橋田満 (20135594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HE Yan-ling (70233640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAMIYA Akira (90124792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 井上正康 (80040278)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 寺崎哲也 (60155463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 前田浩 (90004613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAGATA Masashi (40412829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TAKANO Mikihisa (20211336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OKUDA Masahiro (70252426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HASHIMOTO Yukiya (90228429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IWAKAWA Seigo (50168548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OKUMURA Katsuhiko (60025707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SAKURAI Tunetaro (80127084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. INUI Ken-ichi (70034030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中尾一和 (00172263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 片岡一則 (00130245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YASUHARA Masato 安原 眞人

安原 眞人 ヤスハラ マサト

Research Projects

Research Products

Co-Researchers

Kinetics of drug-induced dysglycemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Kinetics of Dysglycemia Induced by New Quinolone AntibioticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on Organ Correlation of Drug Metabolic Activities by Gene TechnologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Kinetics of Renal Disposition and Action of Bioactive PeptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ドラッグデリバリーの空間的・時間的制御

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ドラッグデリバリーの空間的・時間的制御

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Population Analysis of Pharmacokinetics and Pharmacodynamics of an Immunosuppresive AgentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Kinetics of Rena1 Dispositon and Pharmacological Effect of PeptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Scientific Basis of Drug Disposition in the Kidney and its Application to Clinical Dosage Regimens.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pharmacokinetics and Pharmacodynamics of Antiarrhythmic Drugs in Disease State

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of population pharmacokinetics to the individualization of drug dosage regimen.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pharmacokinetic–Pharmacodynamic Analysis of Sunitinib-Induced Thrombocytopenia in Japanese Patients with Renal Cell Carcinoma2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Effects of Moxifloxacin on Serum Glucose Concentrations in Rats2013

YASUHARA Masato 安原眞人

安原眞人ヤスハラマサト