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SATO Michihiko
佐藤 道比古
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Researcher Number
00135344
Affiliation
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2012 : 山形大学, 医学部, 准教授
2007 : Yamagata University, School of Medicine, Associate Professor
2002 – 2006 : 山形大学, 医学部, 助教授
1994 – 1999 : 山形大学, 医学部, 助教授
1989 – 1992 : School of Med. Dept. of Molecular and Pathological Biochemistry, Associate Profe, 医学部, 助教授
1988 : 山形大学, 医学部, 講師
1986 : 山形大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Functional biochemistry
/
代謝生物化学
/
Pathological medical chemistry
Except Principal Investigator
代謝生物化学
/
Functional biochemistry
/
Living organism molecular science
/
Functional biochemistry
/
General medical chemistry
/
Structural biochemistry
/
Legal medicine
Keywords
Principal Investigator
カドミウム / ヘムオキシゲナーゼ / ヘム分解酵素 / ストレスタンパク質 / USF / 転写調節 / 転写制御 / 遺伝子発現調節 / 転写因子 / メタルレスポンシブエレメント
…
More
/ ヒートショックタンパク質 / 蛋白質メチル化 / heat shock protein / cDNAクロ-ニング / cDNA塩基配列解析 / グリオーマ細胞 / Sーアデノシルメチオニン / heme oxygenase / 蛋白質一次構造 / HSP32 / 遺伝子発現 / stress protein / 神経生化学 / ストレス / ストレス関連蛋白質 / 脳 / 蛋白質カルボキシメチル基転移酵素 / CATアッセイ / Methylation / ヘムオキシナーゼ / 異常アスパラギン酸 / cadmium / 老化 / transcriptional control / ヘム分解 / Protein carboxyl methyltransferase / Aging / ヘム / ヘムオキシゲナ-ゼ / Brain / degradation of heme / cDNA for protein carboxyl methyltransferase
…
More
Except Principal Investigator
ヘムオキシゲナーゼ / CO / ビリベルジン / ベルドヘム / ジフテリア菌 / ヘムの分解 / Heme oxygenase / 酸素活性化機構 / heme oxygenase / ビリルビン / Corynebacterium diphtheriae / Hmu O / シアノバクテリア / 酵素活性化 / 環境応答機構 / 大豆ヘムオキシゲナーゼ / CYANOBACTERIUM / フマラーゼ / site directed mutagenesis / Expression in E. coli / Cytosolic factor / Fumarase / 鉄 / Fxtra-peptide / ESI-MSによる逐次反応速度論解析 / ピリルビン / ショウジョウバエ / VERDOHEME / 過酸化水素 / Receptor for precursor protein / enzymatic reaction mechanism / オルニナンアミノ基転移酵素前駆体 / オルニチンアミノ基転移酵素前駆体 / ヘムオキシゲナ-ゼ / 反応調節 / 細胞質因子 / SNP / regulation of reactions / 酸素活性化 / Heme degradation enzyme / ヘム / Production of fumarase / プライマー法 / PCR / Bilirubin / 生物種依存性 / 酵素活性の微調節 / Cyanobacterium / 型特異的プライマー / biliverdin / フマラーゼの生成 / heme pocket / フマラ-ゼのcDNA / PCR法 / 酵素反応機構 / ヘムオキシグナーゼ / ヒドロペルオキソ / cDNA for fumarase / OXYGEN ACTIVATION / Heme degradation / オキシグナーゼ / Soybean, GmHO-1 / 反応制御 / Activation of oxygen / 付加ペプチド / Isozyme / molecular recognition / 細胞内局在化機構 / ミトコンドリア / 塩基置換 / Oxygen activation / タンパク質 / 附加ペプチド / 酵素活性化機構 / 環境変化 / 酸素消費の速度論解析 / Mitochondria / Precursor of Ornithine aminotransferase / BILIVERDIN / フマラーゼのcDNA / フマラ-ゼ / リポソーム / ピリベルジン / Insertion mechanism to microsome / ヘムポケット / フマラ-ゼの生成 / specificity of species / meso-HYDROXYHEME / Verdoheme / CASPA / protein / 小胞体への定着機構 / メソヒドロキシヘム / 大腸菌での発現 / HEME OXYGENASE / HmuO / 蛋白質細胞内局在化機構 / 細菌のヘム分解酵素 / ビリベルジン還元酵素 / 部位指定変異 / ヒドロキシヘム / 前駆体受容体 / HYDROPEROXO SPECIES / 酸性化環境への適応 / CASPA法 / アイソザイム / Hydroxyheme / Biliverdin / 分子認識
Less
Research Projects
(
14
results)
Research Products
(
4
results)
Co-Researchers
(
15
People)
Project Start Year(Newest)
Project Start Year(Oldest)
Heme oxygenase strategy for circumventing environmental changes_fine tuning of activity
Principal Investigator
MIGITA Taiko
Project Period (FY)
2010 – 2012
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Living organism molecular science
Research Institution
Yamaguchi University
How different biological species make heme oxygenase suit their own needs?_Elucidation of the dependence of heme catabolism on species
Principal Investigator
MIGITA Taiko
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamaguchi University
Mechanism of heme degradation by heme oxygenase and diversity of heme oxygenase among the various organisms
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
2004 – 2006
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
Mechanism of heme degradation by heme oxygenase and the interaction of heme
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
Mechanism of heme degradation by heme oxygenase
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (A).
Research Field
Structural biochemistry
Research Institution
YAMAGATA UNIVERSITY
プライマー分析による新しいDNA多型検出法の開発
Principal Investigator
梅津 和夫
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Legal medicine
Research Institution
Yamagata University
重金属ストレスによる群特異的遺伝子転写調節機構の解明
Principal Investigator
Principal Investigator
佐藤 道比古
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
ヘムオキシゲナーゼ遺伝子基本転写因子USFに対するカドミウムの影響
Principal Investigator
Principal Investigator
佐藤 道比古
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
ラットヘムオキシゲナーゼ遺伝子の重金属による転写調節機構
Principal Investigator
Principal Investigator
佐藤 道比古
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
On the role of heme oxygenase as a oxygen radical scavenger
Principal Investigator
Principal Investigator
SATO Michihiko
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Yamagata University
Relation between structure and function of heme oxygenase and its insertion mechanism to microsomal membranes
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
代謝生物化学
Research Institution
Yamagata University
On the Protein Carboxyl Methylation of the Aged Protein in the Brain
Principal Investigator
Principal Investigator
SATO Michihiko
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
代謝生物化学
Research Institution
Yamagata University
Mechanism of the production of two isozymes of fumarase encoded from a single gene
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Yamagata University
Research on the receptor for the precursors of mitochondrial proteins and the cytosolic factor required for their import
Principal Investigator
TUBOI Syozo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
代謝生物化学
Research Institution
Yamagata University School of Medicine, Department of Biochemistry
All
2011
All
Presentation
[Presentation] 反応環境に応答したヘムオキシゲナーゼによるヘム分解の微調整
2011
Author(s)
高田さゆり・佐藤道比古・張旭紅・右田たい子
Organizer
日本生物物理学会第49回年会
Place of Presentation
兵庫県立大学姫路書写キャンパス(姫路市)
Year and Date
2011-09-18
Data Source
KAKENHI-PROJECT-22510232
[Presentation] Fine tuning of the heme catabolism by heme oxygenase in response to the reaction milieu
2011
Author(s)
高田さゆり・佐藤道比古・張極紅・右田たい子
Organizer
日本生物物理学会第49回年会
Place of Presentation
兵庫県立大書写キャンパス(姫路市)
Year and Date
2011-09-18
Data Source
KAKENHI-PROJECT-22510232
[Presentation] ヘムオキシゲナーゼ反応のプロトン・酸素濃度依存性
2011
Author(s)
高田さゆり・張極紅・佐藤道比古・右田たい子
Organizer
第38回生体分子科学討論会
Place of Presentation
筑波大学(つくば市)
Year and Date
2011-06-23
Data Source
KAKENHI-PROJECT-22510232
[Presentation] ヘムオキシゲナーゼ反応のプロトン・酸素濃度依存性
2011
Author(s)
高田さゆり・張旭紅・佐藤道比古・右田たい子
Organizer
第38回生体分子科学討論会
Place of Presentation
筑波大学大学会館(つくば市)
Year and Date
2011-06-23
Data Source
KAKENHI-PROJECT-22510232
# of Projects (Dsc)
# of Projects (Asc)
1.
YOSHIDA Tadashi
(10004673)
# of Collaborated Projects :
11results
# of Collaborated Products :
0results
2.
ISHIKAWA Kazunobu
(80222959)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
3.
ZHANG Xuhong
(10292442)
# of Collaborated Projects :
4results
# of Collaborated Products :
4results
4.
MIGITA Taiko
(90159161)
# of Collaborated Projects :
3results
# of Collaborated Products :
4results
5.
MIGITA Kouto
(90116757)
# of Collaborated Projects :
2results
# of Collaborated Products :
4results
6.
OZAKI Shinichi
(40280581)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
7.
FUJII Hiroshi
(80228957)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
8.
TUBOI Syozo
(70004554)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
9.
ONO Hideyu
(40160915)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
10.
梅津 和夫
(10091828)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
11.
湯浅 勲
(00093633)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
12.
山内 春夫
(30134919)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
13.
鈴木 庸夫
(70004588)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
14.
渡辺 剛太郎
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
15.
OLSOH John S
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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