Miwa Nobuhiko 三羽信比古

… Alternative Names

三羽信比古ミワノブヒコ

MIWA Nobuhiko 三羽信比古

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Researcher Number	00142141
Affiliation (based on the past Project Information) *help	2014 – 2017: 大阪物療大学, 保健医療学部, 教授 2016: 県立広島大学, 生命環境学部, 名誉教授 2011: Prefectural University of Hiroshima, 生命環境学部, 教授 2010: 県立広島大学, 生命環境学部・生命科学科, 教授 2009: Prefectural University of Hiroshima, 生命環境学部, 教授 … More 2007: Prefectural University of Hiroshima, Faculty of Life and Environmental Sciences, Professor 2006: 県立広島大学, 生命環境学部生命科学科, 教授 2005: 県立広島大学, 生命環境学部, 教授 1996 – 1998: 広島県立大学, 生物資源学部・生物資源開発学科, 教授 1993: Hiroshima Prefectural University. School of BioScience.Professor, 生物資源学部, 教授 1991 – 1992: 広島県立大学, 生物資源学部, 助教授 1989: Hiroshima Prefectural University, Faculty of Bio-Resources, Assistant Professor, 生物資源学部・生物工学講座, 助教授 1989: 広島県立大学, 生物資源学部生物工学講座, 助教授 1987 – 1988: 国立予防衛生研究所, 抗生物質部, 主任研究官 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / 動物発生・生理学 Except Principal Investigator Dental engineering/Regenerative dentistry / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator プログラム細胞死 / 神経芽腫細胞 / PROGRAMMED CELL DEATH / DNA切断 / 細胞死 / 活性酸素 / 高性能電気泳動クロマトグラフィ / 単離核 / ヌクレオソーム / DNA断片化 … More / キラー蛋白質 / 神経栄養因子 / 核DNA断片化 / 神経芽腫 / 細胞分化 / 抗キラ-因子 / キラ-因子 / INDUCTION OF DIFFERENTIATION / GLUTAMINE METABOLISM / NEUROBLASTOMA / ANTITUMOR FACTOR / ONTOGENESIS / THE NERVOUS SYSTEM / 糖鎖部分 / 高性能液体クロマトグラフィ / 癌細胞選択的致死作用 / 蛋白質の精製 / リセプタ結合 / 分化促進作用 / 個体発生途上産生物質 / 細胞増殖抑制因子 / 脳由来蛋白質 / 抗がん作用 / 分化誘導 / グルタミン代謝 / 神経芽細胞腫 / 抗がん因子 / 個体発生 / 脳神経系 / Hydrogen-dissolved water / Cell death defense / Hydroperoxide / Reactive oxygen species / dhar Gene / Vitamin C regeneration / 虚血-再灌流障害 / ビタミンC細胞内取込み / 細胞死制御 / 酸化ストレス軽減 / 低酸素-再酸素化 / グルタチオン / デヒドロアスコルビン酸 / 細胞死防御 / dhar遺伝子 / 水素水 / 細包死防御 / ヒドロペルオキシド / dhar遣伝子 / ビタミンC再生 / DNA SCISSION / NEURONAL CELLS / ANTI-KILLER FACTOR / KILLER PROTEIN / APOPTOSIS / ミトコンドリア脱水素酵素 / 神経芽種細胞 / アポトーシス / 抗キラー因子 / NBT還元法 / CDCFH-DA蛍光計測法 / β-カロテン退色法 / 電子スピン共鳴 / フラーレン / バイオテクノロジー / 薬理学 / 化学修飾 / アポトーシシ / 過酸化脂質 / 腎臓、 / 血管内皮細胞 / トランスポーター / アスコルビン酸 / ミトコンドリア脱水素酸素 … More Except Principal Investigator 器官発生 / 神経再生 / 歯髄幹細胞 / HaCaT細胞 / 共培養 / 神経分化能 / 歯髄由来細胞 / 神経新生 / 海馬組織 / スフェロイド / 中枢神経再生 / 歯髄細胞 / 酸化ストレス / 活性酸素種 / 水素医学 / 細胞増殖 / ケラチノサイト / シリカ吸蔵水素 / がん細胞抑制 / 水素水精製装置 / ヒト正常皮膚細胞 / バブリング水素水精製装置 / 水素吸蔵シリカ微粒子 / ヒト正常食道上皮細胞 / ヒト皮膚線維芽細胞 / 細胞骨格 / 糸状仮足 / アポトーシス / 固形シリカ吸蔵水素 / 創傷治癒 / 細胞移動 / 水素水 Less

Exploratory study on cell migration and wound healing of human skin cells treated with hydrogen water
- Principal Investigator
  
  Li Qiang
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Osaka Butsuryo University
Human dental pulp cell-derived spheroids and traditional Chinese medicine for central nerve system regeneration
- Principal Investigator
  
  Xiao Li
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  The Nippon Dental University
フラーレン各種誘導体の化学構造と抗酸化活性との相関性に関する体系的解析Principal Investigator
- Principal Investigator
  
  三羽信比古
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Prefectural University of Hiroshima
Enhancing effects of vitamin C-regeneration gene and vitamin C recycling on prevention of cell deathPrincipal Investigator
- Principal Investigator
  
  MIWA Nobuhiko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Prefectural University of Hiroshima
アスコルビン酸トランスポーター蛋白:その分子的実体の同定、および、血管内皮細胞内へのアスコルビン酸の輸送メカニズムPrincipal Investigator
- Principal Investigator
  
  三羽信比古
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hiroshima Prefectural University
個体発生途上における神経細胞のプログラム死を起こすキラー液性因子Principal Investigator
- Principal Investigator
  
  三羽信比古
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima Prefectural University
個体発生途上における神経細胞のプログラム死を起こすキラ-液性因子Principal Investigator
- Principal Investigator
  
  三羽信比古
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima Prefectural University
PHysiological roles and action Mechanisms of programd cell death in the brain during the ontogenyPrincipal Investigator
- Principal Investigator
  
  MIWA Nobuhiko
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  動物発生・生理学
- Research Institution
  HIROSHIMA PREFECTUAL UNIVERSITY
Physiological role of neonatal brain-derived carcinostatic factor(NBCF) during the ontogenesisPrincipal Investigator
- Principal Investigator
  
  MIWA Nobuhiko
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hiroshima Prefectural University
  国立予防衛生研究所

All 2018 2017 2016 2015 2011 2010 2009 2007 2006 2005

All Journal Article Presentation Book

[Book] 遠藤守信、飯島澄男編「ナノカーボンハンドブック」第2編、第3章、3-2-6節フラーレン誘導体の抗酸化作用と細胞死抑制効果および医療応用2007
- Author(s)
  廖峰, 甘学輝, 肖黎, 松林賢司, Robiul Md. Islam, 斉藤靖和, 三羽信比古
- Publisher
  (株)エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-17590064
[Book] 「抗しわ活性ビタミンC誘導体と分子メカニズム, アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線」第3部、第1章、第2-2節2006
- Author(s)
  河村卓也、斉藤靖和、加藤詠子、続木敏、三羽信比古
- Total Pages
  30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Book] 「ビタミンC高含有果実アセロラの美肌サプリメントとしての効果」アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線」ISBN4-86043-104-9 C3047,第3部・第2章・第4節,pp.339-357、2006年2006
- Author(s)
  三羽信比古
- Total Pages
  19
- Publisher
  NTS出版
- Data Source
  KAKENHI-PROJECT-17590064
[Book] ビタミンC高含有果実アセロラの美肌サプリメントとしての効果.アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線「抗皮膚老化の最前線」第3部.第2章.第4節2006
- Author(s)
  三羽信比古
- Total Pages
  19
- Publisher
  NTS出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Book] 「抗皮膚老化の最前線」第3編.第2章.第4節ビタミンC高含有果実アセロラの美肌サプリメントとしての効果2006
- Author(s)
  三羽信比古
- Publisher
  株式会社ブッカーズ
- Data Source
  KAKENHI-PROJECT-17590064
[Book] 「抗しわ活性ビタミンC誘導体と分子メカニズム」アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線」ISBN4-86043-104-9 C3047, 第3部・第1章・第2-2節,pp.201-2302006
- Author(s)
  河村卓也, 斉藤靖和, 加藤詠子, 続木敏, 三羽信比古
- Total Pages
  30
- Publisher
  NTS出版
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Effects of hydrogen-occluding silica microparticles on wound repair and cell migratory behavior of normal human esophageal epitheliocytes2018
- Author(s)
  Li Q, Tanaka Y, Miwa N
- Journal Title
  
  Medical Gas Research in press
  
  Volume: 8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26350681
[Journal Article] The Lipophilic Vitamin C Derivative, 6-O-Palmitoylascorbate Protects Human Keratinocytes and 3D-Human Skin Equivalents Against X-Ray-Induced Oxidative Stress and Apoptosis More Markedly Than L-Ascorbic Acid.2017
- Author(s)
  Xiao L, Miwa N.
- Journal Title
  
  J Cell Biochem.
  
  Volume: 118 Issue: 2 Pages: 318-329
- DOI
  10.1002/jcb.25639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861689
[Journal Article] Fundamental insight into the methodology of hydrogen water in biological studies2017
- Author(s)
  Li Q, Asada R. Tanaka Y. Miwa N.
- Journal Title
  
  J. Nanosci. Nanotechnol.
  
  Volume: 17 Issue: 7 Pages: 5134-5138
- DOI
  10.1166/jnn.2017.14210
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350681
[Journal Article] Influence of hydrogen-occluding-silica on migration and apoptosis in of human esophageal cells in vitro2017
- Author(s)
  Li, Q; Tanaka, Y; Miwa, N.
- Journal Title
  
  Medical Gas Research
  
  Volume: 16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26350681
[Journal Article] Cover Image2017
- Author(s)
  Xiao L, Miwa N.
- Journal Title
  
  J Cell Biochem
  
  Volume: 118 Issue: 2 Pages: 1-1
- DOI
  10.1002/jcb.25848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861689
[Journal Article] Effects of Platinum Nanocolloid in Combination with Gamma Irradiation on Normal Human Esophageal Epithelial Cells.2016
- Author(s)
  Qiang Li, Yoshiharu Tanaka, Yasukazu Saitoh, and Nobuhiko Miwa. .
- Journal Title
  
  Journal of Nanoscience and Nanotechnology
  
  Volume: 16 Issue: 5 Pages: 5345-5352
- DOI
  10.1166/jnn.2016.12362
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350681
[Journal Article] Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment.2016
- Author(s)
  Xiao L, Miwa N.
- Journal Title
  
  Hum Cell
  
  Volume: 30 Issue: 2 Pages: 72-87
- DOI
  10.1007/s13577-016-0150-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861689
[Journal Article] 水素医学研究概況及び関連文献のビブリオメトリックス解析2015
- Author(s)
  李　強、田中良晴、田中博司、三羽信比古
- Journal Title
  
  大阪物療大学紀要
  
  Volume: 3 Pages: 31-40
- NAID
  110009914847
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26350681
[Journal Article] Anticancer effects of fullerene [C_60] included in polyethylene glycol combined with visible light-irradiation through ROS generation and DNA fragmentation on fibrosarcoma cells with scarce cytotoxicity to normal fibroblasts.2011
- Author(s)
  Liao F, Saitoh Y, Miwa N.
- Journal Title
  
  Oncol Res.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Super-highly hydroxylated fullerene derivative protects human keratinocytes from UV-induced cell injuries together with the decreases in intracellular ROS generation and DNA damages.2011
- Author(s)
  Saitoh Y, Miyanishi A, Mizuno H, Kato S, Aoshima H, Kokubo K, Miwa N.
- Journal Title
  
  J Photochem Photobiol B.
  
  Volume: Vol.102(1) Pages: 69-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Fullerene-C60 incorporated in liposome exerts persistent hydroxyl radical-scavenging activity and cytoprotection in UVA/B-irradiated keratinocytes.2011
- Author(s)
  Kato S, Aoshima H, Saitoh Y, Miwa N.
- Journal Title
  
  J Nanosci Nanotechnol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] The effect of squalane-dissolved fullerene-C60 on adipogenesis-accompanied oxidative stress and macrophage activation in a preadipocyte-monocyte co-culture system.2010
- Author(s)
  Xiao L, Aoshima H, Saitoh Y, Miwa N.
- Journal Title
  
  Biomaterials.
  
  Volume: Vol.31 Pages: 5976-5985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Defensive effects of fullerene-C60 dissolved in squalane against the 2, 4-nonadienal-induced cell injury in human skin keratinocytes HaCaT and wrinkle formation in 3D-human skin tissue model.2010
- Author(s)
  Kato S, Aoshima H, Saitoh Y, Miwa N
- Journal Title
  
  J Biomed Nanotechnol
  
  Volume: Vol.6 Pages: 52-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Fullerene-polyvinylpyrrolidone clathrate localizes in the cytoplasm to prevent Ultraviolet-A ray-induced DNA-fragmentation and activation of the transcriptional factor NF-kappa B.2010
- Author(s)
  Xiao L, Aoshima H, Saitoh Y, Miwa N
- Journal Title
  
  J Cell Biochem.
  
  Volume: Vol.111(4) Pages: 955-966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Defensive effects of fullerene-C60/liposome complex against UVA-induced intracellular reactive oxygen species generation and cell death in human skin keratinocytes HaCaT, associated with intracellular uptake and extracellular excretion of fullerene-C60.2010
- Author(s)
  Kato S, Kikuchi R, Aoshima H, Saitoh Y, Miwa N
- Journal Title
  
  J Photochem Photobiol B.
  
  Volume: Vol.98(2) Pages: 144-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Clinical Evaluation of Fullerene-C60 Dissolved in Squalane for Anti-Wrinkle Cosmetics.2010
- Author(s)
  Kato S, Aoshima H, Saitoh Y, Miwa N.
- Journal Title
  
  J Nanosci Nanotechnol.
  
  Volume: Vol.10 Pages: 6769-6774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Fullerene-C60/liposome complex : Defensive effects against UVA-induced damages in skin structure, nucleus and collagen type I/IV fibrils, and the permeability into human skin tissue.2010
- Author(s)
  Kato S, Aoshima H, Saitoh Y, Miwa N.
- Journal Title
  
  J Photochem Photobiol B.
  
  Volume: Vol.98(1) Pages: 99-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes.2010
- Author(s)
  Saitoh Y, Xiao L, Mizuno H, Kato S, Aoshima H, Taira H, Kokubo K, Miwa N
- Journal Title
  
  Free Radical Research
  
  Volume: Vol.44(9) Pages: 1072-1081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] 新規素材の美肌・抗老化・抗メタボ効能に関する化粧品・美肌サプリメントとしての研究開発動向～主に水素・白金・フラーレン・プロビタミンC/E・炭酸ガス・天然系抗酸化剤について～2010
- Author(s)
  斉藤靖和, 加藤信哉, 肖黎(Xiao Li), 三羽信比古
- Journal Title
  
  Cosmetic Stage
  
  Volume: 5巻 Pages: 47-62
- NAID
  40017367004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and the permeability into the human skin tissue2009
- Author(s)
  Kato Shinya, Aoshima Hisae, Saitoh Yasukazu, Miwa Nobuhiko
- Journal Title
  
  Basic & Clinical Pharmacology & Toxicology 104(6)
  
  Pages: 483-487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Safety evaluation of highly purified fullerenes : based on screening of eye, skin and cell damages2009
- Author(s)
  Kato Shinya, Aoshima Hisae, Saitoh Yasukazu, Ito Shinobu, Yamana Shuichi, Miwa Nobuhiko
- Journal Title
  
  Journal of Toxicological Sciences 34(5)
  
  Pages: 555-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Biological safety of Liposome Fullerene consisting of hydrogenated lecithin, glycine soja sterols and fullerene-C60 upon photocytotoxicity and bacterial reverse mutagenicity2009
- Author(s)
  Kato Shinya, Aoshima Hisae Saitoh Yasukazu, Miwa Nobuhiko
- Journal Title
  
  Toxicology & Industrial Health 25(3)
  
  Pages: 197-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Highly-hydroxylated or γ-cyclodextrin-bicapped water-soluble derivative of fullerene : the antioxidant ability assessed by electron spin resonance method and β-carotene bleaching assay2009
- Author(s)
  Kato Shinya, Aoshima Hisae, Saitoh Yasukazu, Miwa Nobuhiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 19
  
  Pages: 5293-5296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590099
[Journal Article] Anti-tumor and anti-invasive effects of diverse new macrocyolic lactones,alkylolides and alkenylolides,and their enhancement by hyperthermia.2007
- Author(s)
  Tanaka H, Kageyama K. Kusumoto K, Miwa N
- Journal Title
  
  Oncol Reports 18
  
  Pages: 1267-1262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Age-dependent telomere-shortening is repressed by phosphorylated tocopherol together with cellular longevity and oxidative-stress reduction in human brain endotheliocytes2007
- Author(s)
  Tanaka Y, Moritoh Y, Miwa N
- Journal Title
  
  J Cell Biochem 102
  
  Pages: 789-703
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Cytoprotective effect of fnut extracts associated with antioxidant activ a ainst ultraviolet rays2007
- Author(s)
  Kondo S, Yosbikawa H, Miwa N.
- Journal Title
  
  Food Chemistry 104
  
  Pages: 1272-1276
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Transfection with glutathione-dependent dehydroascorbate reductase genes exerts cytoprotective effects against hydroperoxide-induced cell injury through vitamin C regeneration and oxidative-stress diminishment2007
- Author(s)
  Saitoh Y, Fukuoka Y, Nishilcimi M, Miwa, N
- Journal Title
  
  (Reviewed) Vol. 11(Reviewed)
  
  Pages: 143-150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Anti-tumor and anti-invasive effects of diverse delta-allyl-lactones:dependence on molecular side-chain length,action riod and intracellular uptake2007
- Author(s)
  Tanaka Y, Kageyama K, Yoshimura Y, Kusumoto K, Asada R Miwa N.
- Journal Title
  
  Life Sciences 24
  
  Pages: 1851-1855
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Evaluation of permeability of hair growing ingredient encapsulated PLGA nanospheres to hair follicles and their hair growing effects2007
- Author(s)
  Tsujimoto H, Hara K, Tsukada Y, Huang C.C., Kawashima Y, Arakaki M, Mimura H, Miwa N
- Journal Title
  
  Bioorg Med Chem Lett 17
  
  Pages: 4771-4777
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Anti-tumor and anti-invasive effects of diverse delta-alkyl-lactones:dependence on molecular side-chain length,action period and intracellular uptake.2007
- Author(s)
  Tanaka Y, Kageyama K, Yoshimura Y, Kusumoto K, Asada R, Miwa N.
- Journal Title
  
  Life Sciences 24
  
  Pages: 1851-1855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Anti-tumor and anti-invasive effects of diverse delta-alkyl-lactones : dependence on molecular side-chain length, action period and intracellular uptake2007
- Author(s)
  Tanaka Y, Kageyama K, Yoshimura Y, Kusumoto K, Asada R, Miwa, N
- Journal Title
  
  Life Sciences(Reviewed) Vol. 24
  
  Pages: 1851-1855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Apoptosis prevention in neuronally differentiated PC12 cells,by bcl-2 gene trausfection in the non-proliferative and differentiated state,with retention of neuron-specific proteins and blockage of mitocondrion-relayed apoptotic pathway2007
- Author(s)
  Saitoh Y, Masumoto S, Yanada S, Miwa N
- Journal Title
  
  Gene Therapy & Molecular Biology 11
  
  Pages: 275-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Apoptosis prevention in neuronally differentiated PC12 cells,by bcl-2 gene transfection in the non-proliferative and differentiated state,with retention of neuron-specific proteins and blockage of mitocondrion-relaed apoptotic pathway2007
- Author(s)
  Saitoh Y, Masumoto S, Yanada S, Miwa N
- Journal Title
  
  Gene Therapy & Molecular Biology 11
  
  Pages: 275-288
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Transfection with glutathione-dependent dehydroascorbate reductase genes exerts cytoprotective effects against hydroperoxide-induced cell injury through vitamin C re eneration and oxidative-stress diminishment2007
- Author(s)
  Saitoh Y, Fukuoka Y, Nishikimi M, Miwa N
- Journal Title
  
  Gene Therapy & Molecular Biology 11
  
  Pages: 143-150
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Effects of ethyl-esterization,chain-lengths,unsaturation degrees,and hyperthermia on carcinostatic effect of omega-hydroxylated fatty acids2007
- Author(s)
  Kusumoto K, Kageyama K, Matsuda T, Takanori T. Tbmura, Tanaka H, Yazama F, Miwa N
- Journal Title
  
  Exptl Oncol 29
  
  Pages: 106-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Effects of ethyl-esterization,chain-lengths,unsaturation degrees,and hyperthermia on carcinostatic effect of omega-hydroxylated fatty acids2007
- Author(s)
  Kusumoto K, Kageyama K, Matsuda T, Takanori T.Tomura, Tanaka H, Yazama F, Miwa N
- Journal Title
  
  Exptl Oncol 29
  
  Pages: 106-110
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Age-dependent telomere-shortening is repressed by phosphorylated tocopherol together with cellular longevity and oxidative-stress reduction in human brain endotheliocytes.2007
- Author(s)
  Tanaka Y, Moritoh Y, Miwa N
- Journal Title
  
  J Cell Biochem 102
  
  Pages: 789-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Effects of ethyl-esterization, chain-lengths, unsaturation degrees, and hyperthennia on carcinostatic effect of omega-hydroxylated fatty acids2007
- Author(s)
  Kusumoto K, Kageyama K, Matsuda T, Takanori T, Tomura, Tanaka H, Yazama F, Miwa, N
- Journal Title
  
  Exptl Oncol(Reviewed) Vol. 29
  
  Pages: 106-110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Evaluation of permeability of hair growing ingredient encapsulated PLGA nanospheres to hair follicles and their hair growing effects2007
- Author(s)
  Tsujimoto H, Hara K, Tsukada Y, Huang C. C., Kawasihima Y, Arakaki M, Mimura H, Miwa N
- Journal Title
  
  Bioorg Med Chem Lett 17
  
  Pages: 4771-4777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Anti-tumor and anti-invasive effects of diverse new macrocyclic lactones,alkylolides and alkenylolides,and their enhancement by hyperthennia2007
- Author(s)
  Tanaka H, Kageyama K, Kusumoto K, Miwa N
- Journal Title
  
  Oncol Reports 18
  
  Pages: 1267-1262
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Transfection with glutathione-dependent dehydroascoibate reductase genes exerts cytoprotective effects against hydroperoxide-induced cell injury through vitamin C regeneration and oxidalive-stress diminishment2007
- Author(s)
  Saitoh Y, Fukuoka Y, Nishikimi M, Miwa N
- Journal Title
  
  Gene Therapy & Molecular Biology 11
  
  Pages: 143-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Cytoprotective effect of fruit extracts associated with antioxidant activity against ultraviolet rays.2007
- Author(s)
  Kondo S, Yoshikawa H, Miwa, N
- Journal Title
  
  Food Chemistry(Reviewed) Vol. 104
  
  Pages: 1272-1276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Apoptosis prevention in neuronally differentiated PC12 cells, by bcl-2 gene transfection in the non-proliferative and differentiated state, with retention of neuron-specific proteins and blockage of mitocondrion-relayed apoptotic pathway2007
- Author(s)
  Saitoh Y, Masumoto S, Yanada S, Miwa, N
- Journal Title
  
  (Reviewed) Vol. 11(Reviewed)
  
  Pages: 275-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Evaluation of penneability of hair growing ingredient encapsulated PLGA nanospheres to hair follicles and their hair growing effects2007
- Author(s)
  Tsujimoto H, Hara K, Tsukada Y, Huang, C. C., Kawashima Y, Arakaki M, Mimura H, Miwa, N
- Journal Title
  
  Bioorg Med Chem Lett(Reviewed) Vol. 17
  
  Pages: 4771-4777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Inhibitory effect of water-soluble polymer-wrapped fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in melanocytes and skin tissues2007
- Author(s)
  Xiao L, Matsubayashi K, Miwa, N
- Journal Title
  
  Arch Dermatol Res(Reviewed) Vol. 299
  
  Pages: 245-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Inhibitory effect of water-soluble polymer-wrapped fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in melanocytes and skin tissucs2007
- Author(s)
  Xiao L, Matsubayashi K, Miwa N
- Journal Title
  
  Arch Dermatol Res 299
  
  Pages: 245-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Cytoprotective effect of fruit extracts associated with antioxidant activity against ultraviolet rays.2007
- Author(s)
  Kondo S, Yoshikawa H, Miwa N.
- Journal Title
  
  Food Chemistry 104
  
  Pages: 1272-1276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Age-dependent telomere-shortening is repressed by phosphorylated tocopherol together with cellular longevity and oxidative-stress reduction in human brain endotheliocytes2007
- Author(s)
  Tanaka Y, Moritoh Y, Miwa, N
- Journal Title
  
  J Cell Biochem(Reviewed) Vol. 102
  
  Pages: 89-703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Anti-tumor and anti-invasive effects of diverse new macrocyclic lactones, alkylolides and alkenylolides, and their enhancement by hyperthermia2007
- Author(s)
  Tanaka H, Kageyama K, Kusumoto K, Miwa, N
- Journal Title
  
  Oncol Reports(Reviewed) Vol. 18
  
  Pages: 1267-1262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Inhibitory effect of water-soluble polymer-wrapped fullerene on U VA-induced melanogenesis viadownre ation of rosinase ex ession in melanoc s and skin tissues2007
- Author(s)
  Xiao L, Matsubayashi K, Miwa N
- Journal Title
  
  Arch Dermatol Res 299
  
  Pages: 245-257
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Effects of vitamin C-rich fruit acerola as skin-rejuvenating supplements2006
- Author(s)
  Nobuhiko, MIWA
- Journal Title
  
  Anti-aging series "Front-line of Skin Anti-aging Research"(NTS Publishing Co.) Vol. 2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Transfection of the anti-apoptotic gene bcl-2 inhibits oxidative stress-induced cell injuries through delaying of NF-kB activation.2006
- Author(s)
  Shinobu Yanada, Masashi Misumi, Yasukazu Saitoh, Yasufumi Kaneda, Nobuhiko Miwa
- Journal Title
  
  Gene Therapy ＆ Molecular Biology 10巻
  
  Pages: 269-276
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Transfection of the anti-apoptotic gene bcl-2 inhibits oxidative stress-induced cell injuries through laying of NF-kB activation"2006
- Author(s)
  Shinobu Yanada, Masashi Misumi, Yasukazu Saitoh, Yasufumi Kaneda, Nobuhiko Miwa
- Journal Title
  
  Gene Therapy & Molecular Biology 10巻
  
  Pages: 269-276
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Preventive effects of phosphorylated ascorbate on ultraviolet-B induced apoptotic cell deathand DNA rand cleavage through enrichment of intracellular vitamin C in skin epidermal keratinocytes2006
- Author(s)
  Sugimoto M, Okugawa Y, Miwa, N
- Journal Title
  
  Free Radical Research(Reviewed) Vol. 40
  
  Pages: 213-221
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Preventive effects of phosphorylated ascorbate on ultraviolet-B induced apoptotic cell death and DNA strand cleavage through enrichment of intracellular vitamin C in skin epidermal keratinocytes2006
- Author(s)
  Sugimoto M, Okugawa Y, Miwa N.
- Journal Title
  
  Free Radical Research 40巻
  
  Pages: 213-221
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Anti-wrinkle activity of vitamin C derivatives and the molecular mechanism2006
- Author(s)
  Kawamura T, Saitoh Y, Kato E, Tsuzuki T, Miwa, N
- Journal Title
  
  Anti-aging series "Front-line of Skin Anti-aging Research"(NTS Publishing Co.) Vol. 2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Transfection of the anti-apoptotic gene bc1-2 inhibits oxidative stress-induced cell injuries through delaying of NF-kB activation2006
- Author(s)
  Shinobu, Yanada, Masashi, Misurni, Yasukazu, Saitoh, Yasufumi, Kaneda, Nobuhiko, Miwa
- Journal Title
  
  (Reviewed) Vol. 10(Reviewed)
  
  Pages: 269-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Preventive effects of phosphorylated ascorbate on ultraviolet-B induced apoptotic cell death and DNA strand cleavage through enrichment of intracellular vitamin C in skin epidermal keratinocytes.2006
- Author(s)
  Sugimoto M, Okugawa Y, Miwa N.
- Journal Title
  
  Free Radical Research 40巻2号
  
  Pages: 213-221
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Hemagglutinating virus of Japan-artificial viral envelope liposome-mediated cotransfer of bag-1 and bcl-2 gene rotects hepatic cells against ischemic injury through BAG-1-assisted preferential enhancement of bcl-2 protei xnression2005
- Author(s)
  Yanada S, Sasaki M, Takayama S, Kaneda Y, Miwa, N
- Journal Title
  
  Human Gene Therapy(Reviewed) Vol. 16
  
  Pages: 627-633
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Hemagglutinating virus of Japan- artificial viral envelope liposome-mediated cotransfer of bag-1 and bcl-2 genes protects hepatic cells against ischemic injury through BAG-1-assisted preferential enhancement of bcl-2 protein expression.2005
- Author(s)
  Yanada S, Sasaki M, Takayama S, Kaneda Y, Miwa N.
- Journal Title
  
  Human Gene Therapy. 16巻5号
  
  Pages: 627-633
- Data Source
  KAKENHI-PROJECT-17590064
[Journal Article] Hemagglutinating virus of Japan-artificial viral envelope liposome-mediated cotransfer of bag-1 and bcl-2 genes protects hepatic cells against ischemic injury through BAG-1-assisted preferential enhancement of bcl-2 protein expession2005
- Author(s)
  Yanada S, Sasaki M, Takayama S, Kaneda Y, Miwa N.
- Journal Title
  
  Human Gene Therapy 16巻
  
  Pages: 627-633
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590064
[Presentation] バブリング水素水が正常ヒト線維芽細胞の移動能に及ぼす影響について2017
- Author(s)
  李　強、朝田　良子、田中良晴、三羽信比古
- Organizer
  第7回日本分子状水素医学生物学会大会
- Data Source
  KAKENHI-PROJECT-26350681
[Presentation] Protective effects of hydrogen-rich water on free radical initiators-induced oxidative stress injuries in human gingival fibroblasts and three-dimensional gingival tissue equivalents2016
- Author(s)
  肖　黎、三羽　信比古
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26861689
[Presentation] Biological effects of hydrogen-occluding silica in combination with gamma-ray radiation or X-ray on human esophageal squamous cell carcinoma (KYSE-70 cells) and normal human esophageal epithelial cells (HEEpiC)2016
- Author(s)
  Li, Q; Asada, R; Tanaka, Y. Miwa, N
- Organizer
  第59回日本放射線影響学会学術大会
- Place of Presentation
  JMSアステールプラザ（広島県・広島市）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-26350681
[Presentation] リポソーム包含フラーレンの抗酸化活性:UVA/B照射下でのヒドロキシルラジカル消去活性、細胞死防御、β-カロテン退色防御効果Antioxidant activity of fullerenes/liposome complex by ESR under UVA/B irradiation, cytoprotective effect, and β-carotene bleaching method.2010
- Author(s)
  加藤信哉, 青島央江, 平良光, 山名修一, 斉藤靖和, 三羽信比古
- Organizer
  日本香粧品学会
- Place of Presentation
  有楽町朝日ホール(東京都)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21590099
[Presentation] PVP包接フラーレンとプロビタミンC(AA2G),アスタキサンチンの併用による抗酸化効果および紫外線傷害抑制効果Combinational Effects of PVP/C_60 and AA2G or Astaxanthin on Antioxidant Activity and UV Irradiation-induced Cell Injuries.2010
- Author(s)
  斉藤靖和, 加藤信哉, 角井雅之, 青島央江, 平良光, 山名修一, 三羽信比古
- Organizer
  日本香粧品学会
- Place of Presentation
  有楽町朝日ホール(東京都)
- Year and Date
  2010-06-03
- Data Source
  KAKENHI-PROJECT-21590099
[Presentation] 無作為化二重盲検マッチドペア比較試験によるフラーレンのシワ改善効果の検証2010
- Author(s)
  青島央江, 伊藤雅之, 平良光, 加藤信哉, 斉藤靖和, 三羽信比古
- Organizer
  日本抗加齢医学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21590099
[Presentation] リポソーム包含フラーレンによる紫外線A波防御効果～ヒト皮膚角化細胞の細胞死防御および3D皮膚モデルでの肌保護効果～2009
- Author(s)
  加藤信哉, 青島央江, 平良光, 山名修一, 斉藤靖和, 三羽信比古
- Organizer
  日本香粧品学会
- Place of Presentation
  ヤクルトホール(東京都)
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21590099
[Presentation] 新規3次元セルライト皮膚モデルを用いた高度水酸化フラーレンのリンパ様細胞U937活性化抑制効果の検証2009
- Author(s)
  肖黎, 青島央江, 平良光, 山名修一, 斉藤靖和, 三羽信比古
- Organizer
  日本香粧品学会
- Place of Presentation
  ヤクルトホール(東京都)
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21590099

1. 長尾則男 (40227989)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. SAITOH Yasukazu (90405514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
3. Li Qiang (60621860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. MIZUNO Satoshi (60072930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUNO Tetsuya (30109970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Xiao Li (80548256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. 田中良晴 (60236651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 朝田良子 (60546349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 高坂新一 (50112686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. XIAO Li (10405516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 河地信哉 (70438290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GAN Xuehui (20405517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 谷孝二 (30405518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Miwa Nobuhiko 三羽 信比古

三羽 信比古 ミワ ノブヒコ

MIWA Nobuhiko 三羽 信比古

Research Projects

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Co-Researchers

Exploratory study on cell migration and wound healing of human skin cells treated with hydrogen water

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Human dental pulp cell-derived spheroids and traditional Chinese medicine for central nerve system regeneration

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フラーレン各種誘導体の化学構造と抗酸化活性との相関性に関する体系的解析Principal Investigator

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Enhancing effects of vitamin C-regeneration gene and vitamin C recycling on prevention of cell deathPrincipal Investigator

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アスコルビン酸トランスポーター蛋白:その分子的実体の同定、および、血管内皮細胞内へのアスコルビン酸の輸送メカニズムPrincipal Investigator

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個体発生途上における神経細胞のプログラム死を起こすキラー液性因子Principal Investigator

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個体発生途上における神経細胞のプログラム死を起こすキラ-液性因子Principal Investigator

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PHysiological roles and action Mechanisms of programd cell death in the brain during the ontogenyPrincipal Investigator

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Physiological role of neonatal brain-derived carcinostatic factor(NBCF) during the ontogenesisPrincipal Investigator

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[Book] 遠藤 守信、飯島 澄男 編「ナノカーボンハンドブック」第2編、第3章、3-2-6節フラーレン誘導体の抗酸化作用と細胞死抑制効果および医療応用2007

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[Book] 「抗しわ活性ビタミンC誘導体と分子メカニズム, アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線」第3部、第1章、第2-2節2006

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[Book] 「ビタミンC高含有果実アセロラの美肌サプリメントとしての効果」アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線」ISBN4-86043-104-9 C3047,第3部・第2章・第4節,pp.339-357、2006年2006

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[Book] ビタミンC高含有果実アセロラの美肌サプリメントとしての効果.アンチ・エイジングシリーズ第2巻「皮膚の抗老化最前線「抗皮膚老化の最前線」第3部.第2章.第4節2006

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[Book] 「抗皮膚老化の最前線」第3編.第2章.第4節ビタミンC高含有果実アセロラの美肌サプリメントとしての効果2006

Author(s)

Miwa Nobuhiko 三羽信比古

三羽信比古ミワノブヒコ

MIWA Nobuhiko 三羽信比古

[Book] 遠藤守信、飯島澄男編「ナノカーボンハンドブック」第2編、第3章、3-2-6節フラーレン誘導体の抗酸化作用と細胞死抑制効果および医療応用2007