Tsuji Tsutomu 辻勉

… Alternative Names

TSUJI Tsutomu 辻勉

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Researcher Number	00143503
Other IDs
Affiliation (based on the past Project Information) *help	2019: 城西大学, 薬学部, 客員教授 2017 – 2018: 星薬科大学, 薬学部, 教授 2011 – 2015: 星薬科大学, 薬学部, 教授 2007 – 2008: Hoshi University, 薬学部, 教授 1997 – 2003: 星薬科大学, 薬学部, 教授 … More 1998 – 1999: 星薬科大学, 教授 1992 – 1996: Univ. Tokyo Pharm. Sci. Assoc.Prof, 薬学部, 助教授 1991: 東京大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / 医薬分子機能学 / Environmental and hygienic pharmacy / Biological pharmacy / Structural biochemistry Except Principal Investigator Biological pharmacy / Functional biochemistry / 物質生物化学
Keywords	Principal Investigator 細胞接着 / サイトカイン / セレクチン / 白血球 / インテグリン / 活性酸素 / VLA-3 / Cell adhesion / 血小板 / ラミニン … More / 細胞表面糖鎖 / 細胞外マトリックス / 細胞運動 / シアル酸 / シアリルルイスX / 腫瘍壊死因子 / Laminin / Integrin / Oxygen radical / Leukocyte / Platelet / Selectin / 糖鎖 / 炎症 / 転写因子 / 腹膜播種 / マトリックス分解酵素 / TNF / 糖タンパク質 / P-セレクチン / VLA / アルギナーゼ / NO合成酵素 / インターロイキン6 / 免疫調節 / NF-κB / 一酸化窒素 / 炎症性サイトカイン / エンドトキシン / マクロファージ / Promoter / Luciferase assay / Transcription factor / Cell motility / メラノーマ / 上皮細胞 / ラミニン5 / Ets / 細胞接着分子 / ルシフェラーゼ / 転写制御 / プロモーター / ルシフェラーゼアッセイ / Hemodialysis / Sulfated carbohydrate / Sialic acid / Reactive oxygen species / P-selectin / 炎症反応 / 生体適合性 / 抗接着療法 / 血液透析 / 硫酸化糖鎖 / Peritoneal metastasis / Extracellular matrix / 胃癌細胞 / 腹膜転移 / Cytokine / Glycoprotein / leukocyte / Sialyl Lewis X / CARBOHYDRATE CHAIN / SELECTIN / CYTOKINE / OXYGEN RADICAL / INFLAMMATION / CELL ADHESION / LEUKOCYTE / PLATELET / スーパーオキシド / Carbohydrate chain / Inflammation / Adhesion molecule / 接着分子 / マトリックスメタロプロテイナーゼ / MMP / SSL / 黄色ブドウ球菌 / 細菌分泌タンパク質 / 白血球浸潤 / 腫瘍関連マクロファージ / メタロプロテイナーゼ / 腹膜播種転移 / がん浸潤 / がん浸潤・転移 / 浸潤・転移 / がん / 好中球 / シアリルルイス X / 糖鎖リガンド … More Except Principal Investigator 細胞認識 / レクチン / 細胞接着 / ムチン / 細胞交通 / 白血球 / マクロファージ / TRANSMEMBRANE 4 SUPERFAMILY / CYTOSKELETON / CELL ADHESION / INTEGRIN / LAMININ / BASEMENT MEMBRANE / シグナル伝達 / TM4SF / 基底膜 / ラミニン / 細胞外マトリックス / インテグリン / Cancer metastasis / Lewis antigen / Macrophage / Cellular trafficking / Cellular recognition / O-glysylation / Lectin / mucin / O-グリュシレーション / 癌転転 / 糖鎖 / 癌転移 / ルイス抗原 / 腫瘍免疫 / O-グリコシレーション / Recognition / Cellular / Glycosylation / MUC1 / Monoclonal Antibody / Mucin / 腸内細菌 / グリコシレーション / モノクローナル抗体 / Selectin / Metastasis / Tumor antigen / Poly-N-acetyllactosamine / Macrophage lectin / Sialyl-Le^x / platelet / macrophoge / recognition / carbohydrate / selectin / lectin / スレオニン結合型糖鎖 / セリン / セレクチン / 転移 / 腫瘍抗原 / ポリNアセチルラクトサミン / マクロファージレクチン / シアリルルイス-X糖鎖 Less

Protection against endotoxin shock though stabilization of macrophages by platelet-derived factorsPrincipal Investigator
- Principal Investigator
  
  Tsuji Tsutomu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Josai University
  Hoshi University
Suppression of host defense system by bacterial "cell adhesion-perturbing proteins"Principal Investigator
- Principal Investigator
  
  Tsuji Tsutomu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Hoshi University
Modulation by cytokines of integrin-dependent cancer cell adhesion/invasion to peritoneumPrincipal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
The integrin-matrix interaction in the metastasis and invasion processes of cancerPrincipal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
Regulation of platelet-leukocyte interaction and pharmaceutical applicationPrincipal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Hoshi University
Characterization of VLA-3 integrin-mediated adhesion and its expre ision in cancer cellsPrincipal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
セレクチンと糖鎖を介する細胞間コミュニケーションPrincipal Investigator
- Principal Investigator
  
  辻勉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hoshi University
セレクチンと糖錯を介する細胞間コミュニケーションPrincipal Investigator
- Principal Investigator
  
  辻勉
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hoshi University
Role of VLA-3 integrin in adhesion of cancer cells to peritoneum.Principal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
セレクチンと糖鎖を介する細胞間コミュニケーションPrincipal Investigator
- Principal Investigator
  
  辻勉
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hoshi University
SIGNAL TRANSDUCTION BY INTEGRIN-MATRIX INTERACTION
- Principal Investigator
  
  SEKIGUCHI Kiyotoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Structure and function of a variation of sialyl Lewis X carbohydrate chains on glycoproteins.Principal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
糖結合性細胞接着分子セレクチンによる白血球活性化Principal Investigator
- Principal Investigator
  
  辻勉
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Regulation of cellular trafficking and pathogenesis by mucins
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
VLAインテグリンを介したがん細胞の接着と運動Principal Investigator
- Principal Investigator
  
  辻勉
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of anti-inflammatory drugs affecting functions of platelet adhesion moleculesPrincipal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  University of Tokyo
VLAインテグリンを介したがん細胞運動性の制御Principal Investigator
- Principal Investigator
  
  辻勉
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Establishment of Detection Systems and Expression Systems for Organ-Specific Mucins
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Cell surface glycoconjugates and adhesion molecules
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  The University of Tokyo
Molecular Analysis of Platelet-Immunocyte InteractionPrincipal Investigator
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Selective Cytotoxicity of Staphylococcal α-Hemolysin (α-Toxin) against Human Leukocyte Populations2019
- Author(s)
  Tsuiji Makoto、Shiohara Kazuyuki、Takei Yoshinori、Shinohara Yoshinori、Nemoto Shigeyoshi、Yamaguchi Satoshi、Kanto Masanori、Itoh Saotomo、Oku Teruaki、Miyashita Masahiro、Seyama Yoshiyuki、Kurihara Masaaki、Tsuji Tsutomu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 6 Pages: 982-988
- DOI
  10.1248/bpb.b18-01024
- NAID
  130007657690
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07142, KAKENHI-PROJECT-17K08393
[Journal Article] Stereoisomer-Specific Induction of G2/M Phase Arrest and Apoptosis by 9-(<i>E</i>,<i>Z</i>)-Hydroxyoctadecadienoic Acid in Mouse Lymphoma Cells2019
- Author(s)
  Kodaka A, Hayakawa Y, AlSayegh RJ, Yasuhara T, Tomoda H, Oku T, Dan S, Tsuiji M, Tsuji T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 6 Pages: 937-943
- DOI
  10.1248/bpb.b18-00935
- NAID
  130007657680
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08393
[Journal Article] Generation of a Monoclonal Antibody Against Staphylococcal Superantigen-Like Protein 5 (SSL5) That Discriminates SSL5 from Other SSL Proteins2018
- Author(s)
  Oku Teruaki、Soma Hikari、Kurisaka Chisato、Tsuji Tsutomu
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 37 Issue: 5 Pages: 212-217
- DOI
  10.1089/mab.2018.0016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08393
[Journal Article] Stimulation of Peritoneal Mesothelial Cells to Secrete Matrix Metalloproteinase-9 (MMP-9) by TNF-α: A Role in the Invasion of Gastric Carcinoma Cells2018
- Author(s)
  Oku Teruaki、Shimada Kentaro、Kenmotsu Hiroki、Ando Yusuke、Kurisaka Chisato、Sano Rikio、Tsuiji Makoto、Hasegawa Shinya、Fukui Tetsuya、Tsuji Tsutomu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 12 Pages: 3961-3961
- DOI
  10.3390/ijms19123961
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08393, KAKENHI-PROJECT-18K14908
[Journal Article] Role of sialic acid-containing glycans of matrix metalloproteinase-9 (MMP-9) in the interaction between MMP-9 and staphylococcal superantigen-like protein 52018
- Author(s)
  Kurisaka Chisato、Oku Teruaki、Itoh Saotomo、Tsuji Tsutomu
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 62 Issue: 3 Pages: 168-175
- DOI
  10.1111/1348-0421.12573
- NAID
  40021504688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08393
[Journal Article] Development of splice variant-specific monoclonal antibodies against human alpha3 integrin2016
- Author(s)
  Oku T, Ando Y, Ogura M, Tsuji T
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother
  
  Volume: 35 Issue: 1 Pages: 12-17
- DOI
  10.1089/mab.2015.0053
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670067
[Journal Article] Platelets attenuate production of cytokines and nitric oxide by macrophages in response to bacterial endotoxin2015
- Author(s)
  Ando Y, Oku T, Tsuji T
- Journal Title
  
  Platelets
  
  Volume: 27 Issue: 4 Pages: 1-7
- DOI
  10.3109/09537104.2015.1103369
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670067
[Journal Article] Modulation of matrix metalloproteinase-9 secretion from tumor-associated macrophage-like cells by proteolytically processed laminin-332 (laminin-5).2014
- Author(s)
  Kamoshida, G., Ogawa, T., Oyanagi, J., Sato, H., Komiya, E., Higashi, S., Miyazaki, K., Tsuji, T.
- Journal Title
  
  Clin. Exp. Metastasis
  
  Volume: 31 Issue: 3 Pages: 285-291
- DOI
  10.1007/s10585-013-9627-0
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112517, KAKENHI-PROJECT-23300351, KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-25440033, KAKENHI-PROJECT-25890019
[Journal Article] Development of liposomal nanoconstructs targeting P-selectin (CD62P)-expressing cells by using a sulfated derivative of sialic acid2014
- Author(s)
  Itoh S, Kawano K, Takeshita K, Maitani Y, Tsuji T
- Journal Title
  
  Pharm Res
  
  Volume: (in press) Issue: 10 Pages: 2868-2875
- DOI
  10.1007/s11095-014-1383-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-25460171, KAKENHI-PROJECT-26670067
[Journal Article] Staphylococcal superantigen-like protein 10 (SSL10) inhibits blood coagulation by binding to prothrombin and factor Xa via theirγ-carboxyglutamic acid (Gla) domain2013
- Author(s)
  Itoh S, Yokoyama R, Kamoshida G, Fujiwara T, Okada H, Takii T, Tsuji T, Fujii S, Hashizume H, Onozaki K
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 30 Pages: 21569-21580
- DOI
  10.1074/jbc.m113.451419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590092, KAKENHI-PUBLICLY-24115715, KAKENHI-PROJECT-25291007, KAKENHI-PROJECT-25460170, KAKENHI-PROJECT-25460171, KAKENHI-PROJECT-25460217, KAKENHI-PROJECT-25670151
[Journal Article] Cytokine secretion from human monocytes potentiated by p-selectin-mediated Cell adhesion.2013
- Author(s)
  Suzuki J, Hamada E, Shodai T, Kamoshida G, Kudo S, Itoh S, Koike J, Nagata K, Irimura T, Tsuji T.
- Journal Title
  
  Int Arch Allergy Immunol.
  
  Volume: 160(2) Issue: 2 Pages: 152-60
- DOI
  10.1159/000339857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390018, KAKENHI-PROJECT-23590092
[Journal Article] Integrinα3 is overexpressed in glioma stem-like cells and promotes invasion2013
- Author(s)
  Nakada M, Nambu E, Furuyama N, Yoshida Y, Takino T, Hayashi Y, Sato H, Sai Y, Tsuji T, Miyamoto KI, Hirao A, Hamada JI
- Journal Title
  
  Br J Cancer
  
  Volume: 108 Issue: 12 Pages: 2516-2524
- DOI
  10.1038/bjc.2013.218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-23590356
[Journal Article] Potentiation of tumor cell invasion by co-culture with monocytes accompanying enhanced production of matrix metalloproteinase and fibronectin.2013
- Author(s)
  Kamoshida G, Matsuda A, Miura R, Takashima Y, Katsura A, Tsuji T.
- Journal Title
  
  Clinical & Experimental Metastasis
  
  Volume: 30 Issue: 3 Pages: 289-297
- DOI
  10.1007/s10585-012-9536-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590092
[Journal Article] Staphylococcal superantigen-like protein 8 (SSL8) binds to tenascin C and inhibits tenascin C-fibronectin interaction and cell motility of keratinocytes.2013
- Author(s)
  Itoh S, Yamaoka N, Kamoshida G, Takii T, Tsuji T, Hayashi H, Onozaki K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 433(1) Issue: 1 Pages: 127-32
- DOI
  10.1016/j.bbrc.2013.02.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590119, KAKENHI-PROJECT-22790077, KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-24590085
[Journal Article] Involvement of transcription factor Ets-1 in the expression of the α3 integrin subunit gene.2012
- Author(s)
  Kamoshida G, Matsuda A, Katabami K, Kato T, Mizuno H, Sekine W, Oku T, Itoh S, Tsuiji M, Hattori Y, Maitani Y, Tsuji T.
- Journal Title
  
  FEBS J.
  
  Volume: 279(24) Issue: 24 Pages: 4535-46
- DOI
  10.1111/febs.12040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590115, KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-23790203
[Journal Article] Monocyte differentiation induced by co-culture with tumor cells involves RGD-dependent cell adhesion to extracellular matrix2012
- Author(s)
  Kamoshida G, Matsuda A, Sekine W, Mizuno H, Oku T, Itoh S, Irimura T, Tsuji T
- Journal Title
  
  Cancer Lett
  
  Volume: 315 Issue: 2 Pages: 145-152
- DOI
  10.1016/j.canlet.2011.09.029
- Data Source
  KAKENHI-PROJECT-23590092
[Journal Article] Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin.2012
- Author(s)
  Oku T, Nakano M, Kaneko Y, Ando Y, Kenmotsu H, Itoh S, Tsuiji M, Seyama Y, Toyoshima S ,Tsuji T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287(51) Issue: 51 Pages: 42910-20
- DOI
  10.1074/jbc.m112.349829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590115, KAKENHI-PROJECT-23590092
[Journal Article] Staphylococcal superantigen-like protein 10 binds to phosphartidylserine and apoptotic cells2012
- Author(s)
  Itoh S, Yokoyama R, Murase C, Takii T, Tsuji T, Onozaki K
- Journal Title
  
  Microbiol Immunol
  
  Volume: 56 Pages: 363-371
- Data Source
  KAKENHI-PROJECT-23590092
[Journal Article] Staphylococcal superantigen-like protein 3 binds to the Toll-like receptor 2 extracellular domain and inhibits cytokine production induced by Staphylococcus aureus, cell wall component, or lipopeptides in murine macrophages.2012
- Author(s)
  Yokoyama R, Itoh S, Kamoshida G, Takii T, Fujii S, Tsuji T, Onozaki K.
- Journal Title
  
  Infect Immun.
  
  Volume: 80(8) Issue: 8 Pages: 2816-25
- DOI
  10.1128/iai.00399-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590119, KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-22790077, KAKENHI-PROJECT-23590092
[Journal Article] Laminin-421 produced by lymphatic endothelial cells induces chemotaxis for human melanoma cells2009
- Author(s)
  Saito N, Hamada JI, Furukawa H, Tsutsumida A, Oyama A, Funayama E, Saito A, Tsuji T, Tada M, Moriuchi T, Yamamoto Y
- Journal Title
  
  Pigment Cell Melanoma Res 22(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590084
[Journal Article] Changes in adhesive and migratory characteristics of hepatocellular carcinoma (HCC) cells induced by expression of a3b1 integrin2008
- Author(s)
  Mizuno H, Ogura M, Saito Y, Sekine W, Sano R, Gotou T, Oku T, Itoh S, Katabami K, Tsuji T
- Journal Title
  
  Biochim Biophys Acta 1780
  
  Pages: 564-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590084
[Journal Article] Phorbol ester-dependent phosphorylation regulates the association of p57/coronin-1 with the actin cytoskeleton2008
- Author(s)
  Oku T, Kaneko Y, Murofushi K, Seyama Y, Toyoshima S, Tsuji T
- Journal Title
  
  J Biol Chem 283
  
  Pages: 28918-28925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590084
[Presentation] ヒト由来細胞を利用した新規発熱性物質試験法の開発2020
- Author(s)
  奥　輝明，安藤祐介，人見祐基，築地　信，亀井淳三，林　克彦，菊池　裕，伊豆津健一，工藤由紀子，辻　勉
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 血小板によるマクロファージの機能調節機構の解析2019
- Author(s)
  安藤祐介，奥　輝明，千葉義彦，辻　勉，亀井淳三
- Organizer
  第20回Pharmaco-Hematologyシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌Staphylococcal superantigen-like protein 5（SSL5）の宿主免疫系に与える影響2019
- Author(s)
  奥　輝明，栗坂知里，安藤祐介，人見祐基，築地　信，伊藤佐生智，辻　勉
- Organizer
  第20回Pharmaco-Hematologyシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌SSL5およびSSL11の白血球MMP-9に与える影響2019
- Author(s)
  奥　輝明，栗坂知里，人見祐基，築地　信，辻　勉
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] マウス血小板におけるCoronin-1のリン酸化の解析2019
- Author(s)
  金子　豊，安藤祐介，人見祐基，築地　信，奥　輝明，辻　勉
- Organizer
  第20回Pharmaco-Hematologyシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌Staphylococcal superantigen-like protein 5（SSL5）はヒト血漿C1インヒビターに結合する2019
- Author(s)
  奥輝明，栗坂知里，安藤祐介，辻勉
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌由来SSL5とMMP-9の結合における糖鎖の関与とその特性2018
- Author(s)
  栗坂知里, 奥　輝明, 辻　勉
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌から分泌される SSL11 と白血球 MMP-9 の糖鎖依存的相互作用2018
- Author(s)
  栗坂知里, 奥輝明, 辻勉
- Organizer
  第19回 Pharmaco-Hematology シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌SSL5に対する抗体産生ハイブリドーマの樹立とその性質2018
- Author(s)
  奥　輝明, 相馬光里, 栗坂知里, 辻　勉
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08393
[Presentation] 黄色ブドウ球菌由来SSL5とMMP-9の結合における糖鎖の役割2016
- Author(s)
  栗坂知里，奥　輝明，辻　勉
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670067
[Presentation] 微生物成分に対するマクロファージの応答に及ぼす血小板由来因子の影響2016
- Author(s)
  安藤祐介，奥　輝明，辻　勉
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670067
[Presentation] 血小板はマクロファージのエンドトキシン応答を抑制する2015
- Author(s)
  安藤祐介，奥　輝明，辻　勉
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26670067
[Presentation] 血小板由来可溶性因子はマクロファージのLPSに対する応答を抑制する2015
- Author(s)
  安藤祐介，奥　輝明，辻　勉
- Organizer
  第16回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-06-13
- Data Source
  KAKENHI-PROJECT-26670067
[Presentation] SSL-5とmatrix metalloproteinase 9の結合2015
- Author(s)
  栗坂知里，奥　輝明，伊藤佐生智，辻　勉
- Organizer
  第16回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-06-13
- Data Source
  KAKENHI-PROJECT-26670067
[Presentation] 細胞外マトリックスラミニン-332による単球の腫瘍関連マクロファージへの分化調節2013
- Author(s)
  鴨志田剛,小川崇,小柳潤,佐藤拓揮,古宮栄利子,東昌市,宮崎香,斧康雄,辻勉
- Organizer
  第14回Pharmaco- Hematologyシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] ラミニン-332による単球の分化とマトリックスメタロプロテイナーゼ-9産生調節2013
- Author(s)
  鴨志田剛,小川崇,佐藤拓揮,宮崎香,辻勉
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 転写因子Ets-1による細胞接着分子α3インテグリンの発現調節2012
- Author(s)
  鴨志田剛,辻勉
- Organizer
  第21回がん転移学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 単球との相互作用によるがん細胞の形質変化～がん細胞浸潤とフィブロネクチンおよびTNF-αの役割～2012
- Author(s)
  鴨志田剛,三浦莉紗,高嶋友理,鈴木沙由里,松田彩花,辻勉
- Organizer
  第13回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 単球との相互作用によるがん細胞の形質変化-がん細胞浸潤とフィブロネクチンおよびTNF-αの役割-2012
- Author(s)
  鴨志田剛、三浦莉紗、高嶋友理、鈴木沙由里、松田彩花、辻　勉
- Organizer
  第13回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京（渋谷）
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 腹膜中皮細胞単層培養系を用いた胃がん細胞の浸潤能の評価と炎症性サイトカインの作用2012
- Author(s)
  劍持宏樹,島田賢太郎,奥輝明,築地信,辻勉
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 腹膜中皮細胞単層培養系を用いた胃がん細胞の浸潤能の評価とサイトカインの作用2012
- Author(s)
  劍持宏樹、島田賢太郎、奥　輝明、築地　信、辻　　勉
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] Potentiation of gastric carcinoma cell invasion by TNF-αand MMP secretion from peritoneal mesothelial2012
- Author(s)
  Tsuji, T, Shimada K, Kenmotsu, H, Sekine, W, Saito, Y, Oku, T, Tsuiji, M
- Organizer
  Experimental Biology 2012
- Place of Presentation
  San Diego,米国
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 単球との共培養によるマトリックスメタロプロテイナーゼとフィブロネクチン産生亢進を介したがん細胞浸潤能増強2012
- Author(s)
  鴨志田剛,松田彩花,三浦莉紗,高嶋友理,桂有沙,辻勉
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 細胞外マトリックスタンパク質を介した単球とがん細胞の相互作用における形質変化2011
- Author(s)
  鴨志田剛,松田彩花,桂有沙,三浦莉紗,髙嶋友里,辻勉
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] ヒト末梢血単球とがん細胞の相互作用～細胞外マトリックスタンパク質の働きと癌浸潤～2011
- Author(s)
  鴨志田剛,松田彩花,桂有沙,三浦莉紗,髙嶋友里,辻勉
- Organizer
  第12回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] RGD依存的細胞接着を介した単球の腫瘍馴化マクロファージへの分化とがん細胞接着への影響2010
- Author(s)
  鴨志田剛,辻勉
- Organizer
  第20回日本がん転移学会学術集会・総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 腹膜へのα3β1インテグリン依存的胃がん細胞の接着に対するTNF-αの効果2009
- Author(s)
  島田賢太郎, 奥輝明, 辻勉
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590084
[Presentation] 肝がん細胞株HepG2のインテグリン発現とTNF-αによる細胞死2009
- Author(s)
  後藤敏江, 水野博己, 奥輝明, 伊藤佐生智, 辻勉
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590084
[Presentation] 胃がん細胞の細胞浸潤とラミニン5との相互作用によるMMPとTIMPの発現変化2008
- Author(s)
  関根わか菜, 齋藤雄太, 伊藤佐生智, 奥輝明, 辻勉
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590084
[Presentation] がんの浸潤・転移とα3β1インテグリン-マトリックス相互作用「分子標的創薬研究の最前線-細胞接着システムを標的として-」2008
- Author(s)
  辻勉
- Organizer
  第52回日本薬学会関東支部大会シンポジウム
- Place of Presentation
  東京理科大学薬学部
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19590084
[Presentation] 胃がん細胞のα3β1インテグリンとラミニンの相互作用によるマトリックスメタロプロテイナーゼの産生誘導と細胞浸潤2007
- Author(s)
  関根わか菜, 奥輝明, 伊藤佐生智, 辻勉
- Organizer
  第51回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19590084
[Presentation] 硫酸化シアル酸誘導体NMSO3によるＰ - セレクチン依存的な細胞接着の制御とDDSへの応用
- Author(s)
  伊藤佐生智，小代智紀，工藤早苗，川野久美，米谷芳枝，辻勉
- Organizer
  第15回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  名古屋市立大学
- Year and Date
  2014-05-23 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670067
[Presentation] 細胞外マトリックスラミニン－332による単球の腫瘍関連マクロファージへの分化調節
- Author(s)
  鴨志田剛、小川崇、小柳潤、佐藤拓揮、古宮栄利子、東昌市、宮崎香、斧康雄、辻勉
- Organizer
  第14回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590092

1. IRIMURA Tatsuro (80092146)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. YAMAMOTO Kazuo (20174782)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. IMAI Yasuyuki (80160034)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. OKU Teruaki (20409361)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
5. TSUIJI Makoto (90302611)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. MASUDA Jun-ishi (70173747)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ITOH Saotomo (70308013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. SEKIGUCHI Kiyotoshi (50187845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MEKADA Eisuke (20135742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIYAZAKI Kaoru (70112068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. GU Jianguo (30314420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 工藤早苗 (00267329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 眞鍋理一郎 (30280837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAITO Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. MIZUNO Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. SEKINE Wakana

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. GOTOU Toshie

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. SHIMADA Kentaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. KAMOSHIDA Go

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKAYAMA Hiroo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. CARTER Willi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 瀧井猛将

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Tsuji Tsutomu 辻 勉

TSUJI Tsutomu 辻 勉

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Protection against endotoxin shock though stabilization of macrophages by platelet-derived factorsPrincipal Investigator

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Suppression of host defense system by bacterial "cell adhesion-perturbing proteins"Principal Investigator

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Modulation by cytokines of integrin-dependent cancer cell adhesion/invasion to peritoneumPrincipal Investigator

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The integrin-matrix interaction in the metastasis and invasion processes of cancerPrincipal Investigator

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Regulation of platelet-leukocyte interaction and pharmaceutical applicationPrincipal Investigator

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Characterization of VLA-3 integrin-mediated adhesion and its expre ision in cancer cellsPrincipal Investigator

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セレクチンと糖鎖を介する細胞間コミュニケーションPrincipal Investigator

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セレクチンと糖錯を介する細胞間コミュニケーションPrincipal Investigator

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Role of VLA-3 integrin in adhesion of cancer cells to peritoneum.Principal Investigator

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セレクチンと糖鎖を介する細胞間コミュニケーションPrincipal Investigator

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SIGNAL TRANSDUCTION BY INTEGRIN-MATRIX INTERACTION

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Structure and function of a variation of sialyl Lewis X carbohydrate chains on glycoproteins.Principal Investigator

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糖結合性細胞接着分子セレクチンによる白血球活性化Principal Investigator

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Tsuji Tsutomu 辻勉

TSUJI Tsutomu 辻勉