IMAI Yasuyuki 今井康之

Researcher Number	80160034
Other IDs
Affiliation (Current)	2018 : 静岡県立大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2004 – 2017 : 静岡県立大学, 薬学部, 教授 2000 – 2001 : 静岡県立大学, 薬学部, 教授 1997 : 東京大学, 大学院・薬学系研究科, 助教授 1993 – 1996 : Faculty of Pharmaceutical Sciences, Assistant Professor, 薬学部, 助手 1988 – 1989 : 東京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Environmental pharmacy / Environmental and hygienic pharmacy / Biological pharmacy / Biological pharmacy / Functional biochemistry Except Principal Investigator Biological pharmacy / Biological pharmacy / 物質生物化学 / 医薬分子機能学
Keywords	Principal Investigator MMGL / レクチン / 粘膜免疫 / 抗体医薬 / マクロファージ / IgA / アレルギー・ぜんそく / 免疫学 / 神経科学 / 薬学 … More Except Principal Investigator 糖鎖 / 細胞接着 / 白血球 / 細胞認識 / レクチン / セレクチン / 免疫学 / VLA / リンパ球ホーミング / 細胞交通 / マクロファージ / 細胞運動 / ムチン / インテグリン / リンホトキシン / 炎症 / Monoclonal Antibody / ナチュラルキラ-細胞活性化因子 / シアリルルイス-X糖鎖 / Immunoliposomes / Human melanoma A375 / O-グリュシレーション / interleukin-2 / Tumor antigen / Macrophage lectin / Macrophage / Sialyl-Le^x / MUC1 / 癌壊死因子 / Nude mouse / マクロファ-ジ走化性因子 / 腫瘍免疫 / macrophoge / ルイス抗原 / インタ-ロイキン2 / lymphokine / 癌転転 / INFLAMMATION / イムノリポゾーム / インタ-フェロンガンマ / Recognition / SELECTIN / Glycosylation / ヘパラン硫酸 / Cellular recognition / スレオニン結合型糖鎖 / O-glysylation / recognition / OXYGEN RADICAL / ヌ-ドマウス / natural killer cell activating factor / platelet / 腫瘍抗原 / CYTOKINE / 高内皮細静脈 / 活性酸素 / ナチュラルキラー細胞活性化因子 / Lectin / リンホカイン / マクロファ-ジ活性化因子 / lymphotoxin / CELL ADHESION / シアリルルイスX / CARBOHYDRATE CHAIN / 細胞外マトリックス / Cancer metastasis / Interferon-gamma / Selectin / Mucin / マクロファージ遊走阻止因子 / mucin / 血小板 / tumor necrosis factor / セリン / 癌転移 / スーパーオキシド / lectin / Cellular trafficking / LEUKOCYTE / トランスフェリンレセプタ- / macrophage migration inhibitory factor / マクロファージレクチン / carbohydrate / ケモカイン / L-セレクチン / サイトカイン / ヒトメラノ-マA375 / E-セレクチン / ポリNアセチルラクトサミン / 腸内細菌 / Lewis antigen / Cellular / macrophage activating factor / selectin / イムノリポゾ-ム / PLATELET / Lymphotoxin / TNF / 抗糖鎖抗体 / ナチュラルキラ-活性化因子 / 転移 / インターフェロンーσ / マクロファージ走化性因子 / Metastasis / モノクローナル抗体 / グリコシレーション / O-グリコシレーション / P-セレクチン / Poly-N-acetyllactosamine / マクロファ-ジ遊走阻止因子 Less

Studies on adjuvant chemicals predicted by activation of a nociceptive receptor TRPA1Principal Investigator
- Principal Investigator
  
  Imai Yasuyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Studies on the efficacy of toxin neutralization and safety of Shiga toxin-specific secretory IgA type plantibody produced by practical plantsPrincipal Investigator
- Principal Investigator
  
  Imai Yasuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Mucosal surface defense by edible IgA produced by plantsPrincipal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Role of glycans in chronic inflammation revealed by novel anti-carbohydrate antibodies
- Principal Investigator
  
  KAWASHIMA Hiroto
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University
  Hoshi University
  University of Shizuoka
Adjuvant effect of chemicals on contact hypersensitivity through transient receptor potential channelsPrincipal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Expression of secretory immunoglobulin A in lettuce suitable for the production of therapeutic antibodies in plantfactory.Principal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Analysis of molecular mechanisms underlying lymphocyte homing using high endothelial venule-specific conditional knockout mice
- Principal Investigator
  
  KAWASHIMA Hiroto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Adjuvant effect mechanism on contact sensitization through nociceptive receptorsPrincipal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
リンパ球ホーミングにおける硫酸化糖鎖の多重機能の解明
- Principal Investigator
  
  KAWASHIMA Hiroto
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
接触感作促進作用を有する化学物質の侵害刺激受容チャネルに対する効果Principal Investigator
- Principal Investigator
  
  今井康之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Production of IgA using nasal associated lymphoid tissues toward development of therapeutic antibodies for oral administration.Principal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
細菌由来の糖鎖認識分子に対抗した宿主粘膜免疫系の応答に関する研究Principal Investigator
- Principal Investigator
  
  今井康之
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  University of Shizuoka
Development of functional IgA antibodies against carbohydrate recognition activity of Vero toxin and their application to treatment.Principal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Shizuoka
抗腫瘍性マクロファージの腫瘍認識機構。C-タイプレクチンの関与Principal Investigator
- Principal Investigator
  
  今井康之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Regulation of cellular trafficking and pathogenesis by mucins
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Development of a Method for Cellular Navigation Using a Carbohydrate Recognition Device in Cell TransplantationPrincipal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
VLAインテグリンを介したがん細胞の接着と運動
- Principal Investigator
  
  辻勉
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
抗腫瘍性マクロファージの腫瘍認識機構。C-タイプレクチンの関与Principal Investigator
- Principal Investigator
  
  今井康之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of anti-inflammatory drugs affecting functions of platelet adhesion molecules
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  University of Tokyo
VLAインテグリンを介したがん細胞運動性の制御
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
抗腫瘍性マクロファージの腫瘍抗原の認識機構。C-タイプレクチンの関与。Principal Investigator
- Principal Investigator
  
  今井康之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Establishment of Detection Systems and Expression Systems for Organ-Specific Mucins
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Roles of macrophage C-type lectin in cellular trafficking of normal and malignant cellsPrincipal Investigator
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  UNIVERSITY OF TOKYO
Cell surface glycoconjugates and adhesion molecules
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  The University of Tokyo
Structural Analysis and Mechanisms of Action of Various Inflammatory Cytokines
- Principal Investigator
  
  OSAWA Toshiaki
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  物質生物化学
- Research Institution
  The University of Tokyo
Drug delivery system for the clinical application of cytokines
- Principal Investigator
  
  OSAWA Toshiaki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Protection of human colon cells from Shiga toxin by plant-based recombinant secretory IgA2017
- Author(s)
  Katsuhiro Nakanishi, Shota Morikane, Shiori Ichikawa, Kohta Kurohane, Yasuo Niwa, Yoshihiro Akimoto, Sachie Matsubara, Hayato Kawakami, Hirokazu Kobayashi, Yasuyuki Imai
- Journal Title
  
  Sci. Rep.
  
  Volume : 7 Pages : 45843-45843
- DOI
  10.1038/srep45843
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04660
[Journal Article] Dibutyl maleate and dibutyl fumarate enhance contact sensitization to fluorescein isothiocyanate in mice.2016
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Wakana Suzuki, Erina Ogawa, Kamiyu Kobayashi, and Yasuyuki Imai
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume : 39 Pages : 272-277
- DOI
  10.1248/bpb.b15-00683
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14990
[Journal Article] Autophagy Protects against Colitis by the Maintenance of Normal Gut Microflora and Secretion of Mucus.2015
- Author(s)
  Tsuboi K, Nishitani M, Takakura A, Imai Y, Komatsu M and Kawashima H.
- Journal Title
  
  J Biol Chem.
  
  Volume : 290 Pages : 20511-20526
- DOI
  10.1074/jbc.m114.632257
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14955, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-14J07438, KAKENHI-PROJECT-24390018
[Journal Article] Recombinant IgA specific for influenza A virus hemagglutinin: production, functional analysis and formation of secretory IgA2015
- Author(s)
  Kentaro Shoji, Tadanobu Takahashi, Kohta Kurohane, Koki Iwata, Takeshi Matsuoka, Shogo Tsuruta, Takatomo Sugino, Masaki Miyake, Takashi Suzuki, Yasuyuki Imai
- Journal Title
  
  Viral Immunol.
  
  Volume : 28, Pages : 170-178
- DOI
  10.1089/vim.2014.0098
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670063, KAKENHI-PROJECT-15H05644, KAKENHI-PROJECT-26670064
[Journal Article] Adjuvant effect of an alternative plasticizer diisopropyl adipate on a contact hypersensitivity mouse model: link with sensory ion channel TRPA1 activation.2015
- Author(s)
  Kohta Kurohane, Ayako Kimura, Rie Terasawa, Yurina Sahara, Kamiyu Kobayashi, Wakana Suzuki, Takeshi Matsuoka, Tatsuo Watanabe, and Yasuyuki Imai:
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume : 38 Pages : 1054-1062
- DOI
  10.1248/bpb.b15-00199
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14990
[Journal Article] Novel antibodies reactive with sialyl Lewis X in both humans and mice define its critical role in leukocyte trafficking and contact hypersensitivity responses.2015
- Author(s)
  Matsumura R, Hirakawa J, Sato K, Ikeda T, Nagai M, Fukuda M, Imai Y and Kawashima H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume : 290 Pages : 15313-15326
- DOI
  10.1074/jbc.m115.650051
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14955, KAKENHI-PROJECT-24390018
[Journal Article] Lack of impact of high dietary vitamin A on T helper 2-dependent contact hypersensitivity to fluorescein isothiocyanate in mice.2015
- Author(s)
  Chie Kobayashi, Kohta Kurohane, and Yasuyuki Imai
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume : 38 Pages : 1827-1830
- DOI
  10.1248/bpb.b15-00534
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14990
[Journal Article] Plantibodyの臨床応用2014
- Author(s)
  中西勝宏、黒羽子孝太、今井康之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume : 62 Pages : 192-197
- Data Source
  KAKENHI-PROJECT-25670063
[Journal Article] Stable expression and characterization of monomeric and dimeric recombinant hybrid-IgG/IgA immunoglobulins specific for Shiga toxin.2014
- Author(s)
  Iwata K, Kurohane K, Nakanishi K, Miyake M, Imai Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume : 37 Pages : 1510-1515
- DOI
  10.1248/bpb.b14-00323
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10915, KAKENHI-PROJECT-25670063
[Journal Article] Shiga toxin-induced apoptosis is more efficiently inhibited by dimeric recombinant hybrid-IgG/IgA immunoglobulins than by the parental IgG monoclonal antibodies.2014
- Author(s)
  Kurohane K, Nagano K, Nakanishi K, Iwata K, Miyake M, Imai Y
- Journal Title
  
  Virulence
  
  Volume : 5 Pages : 819-824
- DOI
  10.4161/21505594.2014.973804
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10915, KAKENHI-PROJECT-25670063
[Journal Article] Production of hybrid-IgG/IgA plantibodies with neutralizing activity against Shiga toxin 12013
- Author(s)
  Nakanishi K, Narimatsu S, Ichikawa S, Tobisawa Y, Kurohane K, Niwa Y, Kobayashi H, Imai Y
- Journal Title
  
  PLoS ONE
  
  Volume : 8
- DOI
  10.1371/journal.pone.0080712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10915, KAKENHI-PROJECT-25660008, KAKENHI-PROJECT-25670063
[Journal Article] Role of high endothelial venule-expressed heparan sulfate in chemokine presentation and lymphocyte homing.2013
- Author(s)
  Tsuboi K, Hirakawa J, Seki E, Imai Y, Yamaguchi Y, Fukuda M, and Kawashima H
- Journal Title
  
  J. Immunol.
  
  Volume : 191 Pages : 448-455
- DOI
  10.4049/jimmunol.1203061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390018
[Journal Article] Lack of transient receptor potential melastatin 8 activation by phthalae esters that enhance contact hypersensitivity in mice.2013
- Author(s)
  Kohta Kurohane, Yurina Sahara, Ayako Kimura, Masataka Narukawa, Tatsuo Watanabe, Takashi Daimon, Yasuyuki Imai
- Journal Title
  
  Toxicol. Lett.
  
  Volume : 217 Pages : 192-196
- DOI
  10.1016/j.toxlet.2012.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390031
[Journal Article] High dose dietary pyridoxine induces T-helper type 1 polarization and decreases contact hypersensitivity response to fluorescein isothiocyanate in mice2012
- Author(s)
  Chie Kobayashi, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume : 35 Pages : 532-538
- URL
  https://www.jstage.jst.go.jp/article/bpb/35/4/35_4_532/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390031
[Journal Article] Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model.2012
- Author(s)
  Takahiro Shiba, Takuma Tamai, Yurina Sahara, Kohta Kurohane, Tatsuo Watanabe, Yasuyuki Imai
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume : 264 Pages : 370-376
- DOI
  10.1016/j.taap.2012.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390031
[Journal Article] Establishment of recombinant hybrid-IgG/IgA immunoglobulin specific for Shiga toxin.2011
- Author(s)
  Yuki Tobisawa, Takashi Maruyama, Takashi Tanikawa, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Scand. J. Immunol.
  
  Volume : 76 Pages : 574-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659067
[Journal Article] Essential role of peripheral node address in in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses2011
- Author(s)
  Ohmichi Y, Hirakawa J, Imai Y, Fukuda M, and Kawashima H.
- Journal Title
  
  J.Exp.Med.
  
  Volume : 208 Pages : 1015-1025
- DOI
  10.1084/jem.20101786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390023, KAKENHI-PROJECT-22659018, KAKENHI-PROJECT-23890173
[Journal Article] Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing.2010
- Author(s)
  Hirakawa J, Tsuboi K, Sato K, Kobayashi M, Watanabe S, Takakura A, Imai Y, Ito Y, Fukuda M, Kawashima H
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume : 285 Pages : 40864-40878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390023
[Journal Article] Phthalate esters reveal skin-sensitizing activity of phenethyl isothiocyanate in mice.2010
- Author(s)
  Tomoko Matsuda, Takashi Maruyama, Hiromi Iizuka, Ayumi Kondo, Takuma Tamai, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Food Chem. Toxicol 48
  
  Pages : 1704-1708
- Data Source
  KAKENHI-PROJECT-20390041
[Journal Article] Sulfation of colonic mucins by N-acetylglucosamine-6-O-sulfotransferase-2 and its protective function in experimental colitis in mice2010
- Author(s)
  Tobisawa Y., Imai Y., Fukuda M., Kawashima H.
- Journal Title
  
  Journal of Biological Chemistry 285
  
  Pages : 6750-6760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390023
[Journal Article] Sulfation of colonic mucins by N-acetylglucosamine-6-O-sulfotransferase-2 and its protective function in experimental colitis inmice2010
- Author(s)
  Tobisawa Y, Imai Y, Fukuda M, and Kawashima H.
- Journal Title
  
  J. Biol. Chem
  
  Volume : 285 Pages : 6750-6760
- DOI
  10.1074/jbc.m109.067082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390023, KAKENHI-PROJECT-22659018
[Journal Article] Di-(2-ethylhexyl) phthalate enhances skin sensitization to isocyanate haptens in mice.2010
- Author(s)
  Tomoko Matsuda, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Toxicol. Lett 192
  
  Pages : 97-100
- Data Source
  KAKENHI-PROJECT-20390041
[Journal Article] Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N-and o-glycans in lymphocyte homing2010
- Author(s)
  Hirakawa J, Tsuboi K, Sato K, Kobayashi M, Watanabe S, Takakura A, Imai Y, Ito Y, Fukuda M, and Kawashima H.
- Journal Title
  
  J Biol Chem
  
  Volume : 285 Pages : 40864-40878
- DOI
  10.1074/jbc.m110.167296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390023, KAKENHI-PROJECT-22659018, KAKENHI-PROJECT-22790343
[Journal Article] TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity.2009
- Author(s)
  Takahiro Shiba, Takashi Maruyama, Kohta Kurohane, Yusaku Iwasaki, Tatsuo Watanabe, Yasuyuki Imai
- Journal Title
  
  J. Neuroimmunol 207
  
  Pages : 66-74
- Data Source
  KAKENHI-PROJECT-20390041
[Journal Article] Effects of phthalate esters on the sensitization phase of contact hypersensitivity induced by fluorescein isothiocyanate.2006
- Author(s)
  Yasuyuki Imai
- Journal Title
  
  Clin.Exp.Allergy 36
  
  Pages : 1462-1468
- Data Source
  KAKENHI-PROJECT-18659033
[Journal Article] Production of IgA monoclonal antibody against Shiga toxin binding subunits employing nasal-associated lymphoid tissue.2005
- Author(s)
  Yasuyuki Imai
- Journal Title
  
  J.Immunol.Methods 302
  
  Pages : 125-135
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590055
[Journal Article] Facilitated production of secretory IgA against Shiga toxin B subunits by intranasal application of antigen-coated polystyrene microspheres.2005
- Author(s)
  Kohta Kurohane, Chie Kobayashi, Yasuyuki Imai
- Journal Title
  
  Microbiol.Immunol. 49
  
  Pages : 149-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590055
[Journal Article] Production of IgA monoclonal antibody against Shiga toxin binding subunits employing nasal-associated lymphoid tissue.2005
- Author(s)
  Yasuyuki Imai, Tomoyuki Ishikawa, Takashi Tanikawa, Hiroki Nakagami, Takeshi Maekawa, Kohta Kurohane
- Journal Title
  
  J.Immunol.Methods 302
  
  Pages : 125-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590055
[Presentation] 1型線毛に結合するIgA型イムノアドヘシンの作製2018
- Author(s)
  中西勝宏、黒羽子孝太、今井康之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 植物由来組換え型分泌片を活用した抗原特異的分泌型IgAの構築と消化酵素抵抗性の付与2018
- Author(s)
  菊地祐希、松田弥奈美、森兼捷太、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 分泌型ハイブリッドIgA植物抗体によるベロ毒素のヒト腸管上皮細胞に対する細胞毒性の中和効果の検討2017
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 短鎖・中鎖脂肪酸を有するトリグリセリドによる接触性皮膚炎の感作促進作用2017
- Author(s)
  関口皓太、小川衿菜、堤正人、望月成美、遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Adjuvant effect of short chain fatty acid glycerol esters during sensitization phase of contact hypersensitivity2017
- Author(s)
  Kota Sekiguchi, Erina Ogawa, Hideyuki Konishi, Kei Manabe, Yukina Endo, Masato Tsutumi, Narumi Mochizuki, Kohta Kurohane, Yasuyuki Imai
- Organizer
  The 12th China-Japan Symposium on Health Sciences
- Place of Presentation
  Hangzhou, China
- Year and Date
  2017-02-10
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Enhancing effect of an alternative plasticizer on a contact hypersensitivity mouse model: involvement of TRPA1 activation2017
- Author(s)
  Yasuyuki Imai, Kohta Kurohane, Ayako Kimura, Rie Terasawa, Yurina Sahara, Kamiyu Kobayashi, Wakana Suzuki, Takeshi Matsuoka, Tatsuo Watanabe
- Organizer
  The 12th China-Japan Symposium on Health Sciences
- Place of Presentation
  Hangzhou, China
- Year and Date
  2017-02-10
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 植物で作製した小胞体保留シグナル付加分泌片の糖鎖解析2017
- Author(s)
  梶原優佳、森兼捷太、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] FITC誘導接触性皮膚炎における皮膚感作促進作用：パラベンの評価2017
- Author(s)
  遠藤由貴奈、松岡毅、鈴木若菜、小川衿菜、関口皓太、黒羽子孝太、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Differential effects of high dose dietary vitamin A and B6 on contact hypersensitivity response in mice2017
- Author(s)
  Kohta Kurohane, Chie Kobayashi, Yasuyuki Imai
- Organizer
  The 12th China-Japan Symposium on Health Sciences
- Place of Presentation
  Hangzhou, China
- Year and Date
  2017-02-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 植物で作製した分泌片を活用した分泌型IgAの消化酵素抵抗性に関する研究2017
- Author(s)
  松田弥奈美、森兼捷太、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Production of secretory hybrid-IgG/IgA in plant expression system.2017
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] ベロ毒素に対する分泌型ハイブリッドIgAの植物での産生と細胞内局在の解析2016
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、松原幸枝、秋元義弘、川上速人、小林裕和、今井康之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 小胞体保留シグナルを利用した分泌型IgAの植物での生産性向上2016
- Author(s)
  森兼捷太、細川奈緒、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 接触性皮膚炎におけるTributyrinの感作促進作用2016
- Author(s)
  小川衿菜、関口皓太、遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋市
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 接触性皮膚炎におけるマレイン酸ジブチルのアジュバント作用2016
- Author(s)
  黒羽子孝太、松岡　毅、鈴木若菜、小川衿菜、小林香美結、今井康之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] リンパ球ホーミング阻害に基づくアレルギー性鼻炎抑制2016
- Author(s)
  平川城太朗、今井康之、川島博人
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] 代替可塑剤の免疫促進作用とThymic Stromal Lymphopoietin産生の関係2016
- Author(s)
  関口皓太、鈴木若菜、小川衿菜、黒羽子孝太、今井康之
- Organizer
  日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋市
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Establishment of secretory hybrid IgA with binding to Shiga toxin 1 binding subunit in lettuce2016
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  第21回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 短鎖脂肪酸グリセロールエステルによる接触性皮膚炎の感作促進作用2016
- Author(s)
  関口皓太、小川衿菜、小西英之、眞鍋　敬、遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  フォーラム2016　衛生薬学・環境トキシコロジー
- Place of Presentation
  東京都
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Immunomodulation through transient receptor potential (TRP) channels2016
- Author(s)
  Yasuyuki Imai, Kohta Kurohane, Sumalee Panthong, Arunporn Itharat
- Organizer
  20th World Congress on Clinical Nutrition
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2016-12-14
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Hybrid IgA expressed in Arabidopsis is localized in the protein body-like structure in the leaves2015
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Sachie Matsubara, Yoshihiro Akimoto, Hayato Kawakami, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  植物電子顕微鏡ワークショップ2015
- Place of Presentation
  横浜
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 代替可塑剤によるFITC誘導性接触性皮膚炎の増悪化2015
- Author(s)
  黒羽子孝太、松岡　毅、小林香美結、鈴木若菜、小川衿菜、渡辺達夫、今井康之
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 抗糖鎖抗体S2は鼻咽頭関連リンパ組織へのリンパ球ホーミングを阻害しアレルギー性鼻炎を抑制する2015
- Author(s)
  平川城太朗、今井康之、川島博人
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] Adjuvant effect of dibutyl maleate in an FITC-induced contact hypersensitibvity mouse model2015
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Wakana Suzuki, Kamiyu Kobayashi, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 機能解析を目指した植物発現hybrid IgA抗体の精製2015
- Author(s)
  杉野嵩朋、中西勝宏、鶴田昌吾、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部　合同学術大会2015
- Place of Presentation
  名古屋
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] The role of thymic stromal lymphopoietin in FITC-induced contact hypersensitivity2015
- Author(s)
  Wakana Suzuki, Kamiyu Kobayashi, Takeshi Matsuoka, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Intrarectal administration of Shiga toxin 1 injures mouse colonic epithelial cells2015
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Production of secretory component-KDEL in Arabidopsis thaliana2015
- Author(s)
  Nao Hosokawa, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 静脈内投与により胆汁中に分泌されたShiga toxin特異的hybrid IgAの毒素中和血清と分泌経路の解析2014
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス、熊本市
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Development of neutralizing hybrid-IgG/IgA specific for Shiga toxin.2014
- Author(s)
  Kohta Kurohane, Katsuhiro Nakanishi, Yasuyuki Imai
- Organizer
  11th Japan-China International Symposium on Health Sciences
- Place of Presentation
  静岡県立大学、静岡市
- Year and Date
  2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 大腸ムチンの硫酸化による大腸発癌抑制効果の検討2014
- Author(s)
  西谷麻予、坪井康一郎、飛澤悠葵、金澤寛明、今井康之、川島博人
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] ケモカイン提示とリンパ球ホーミングにおける高内皮細静脈ヘパラン硫酸の機能解析2013
- Author(s)
  坪井康一郎、平川城太朗、關愛実子、今井康之、山口祐、福田穣、川島博人
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] 植物で作製した分泌片の糖鎖解析2013
- Author(s)
  荒木　瞳、中西勝宏、鶴田昌吾、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本病院薬剤師会東海ブロック／日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿医療科学大学白子キャンパス、鈴鹿市
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 接触性皮膚炎の感作過程における代替可塑剤のアジュバント作用機構2013
- Author(s)
  寺澤里恵、木村文子、小林香美結、鈴木若菜、松岡　毅、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック／日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] ベロ毒素に対するIgA植物抗体をめざして2013
- Author(s)
  今井康之、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和
- Organizer
  第25回微生物シンポジウム　～ヒトの健康と微生物～
- Place of Presentation
  静岡県立大学、静岡市
- Invited
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Production of secretory hybrid-IgA specific for Shiga toxin 1 in lettuce.2013
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Production of dimeric hybrid-IgA specific for Shiga toxin 1 in Arabidopsis thaliana.2013
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  Plant-based Vaccines, Antibodies & Biologics
- Place of Presentation
  University of Verona, Verona, Italy
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 免疫応答の制御に有用な新規抗フコシル化糖鎖抗体の樹立2013
- Author(s)
  松村龍志、平川城太朗、永井基瑛、池田俊暁、今井康之、川島博人
- Organizer
  糖鎖科学中部拠点第11回若手の力フォーラム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] 接触性皮膚炎の感作過程における代替可塑剤のアジュバント作用機構2013
- Author(s)
  寺澤里恵, 木村文子, 小林香美結, 鈴木若菜, 松岡毅, 黒羽子孝太, 今井康之
- Organizer
  日本病院薬剤師会東海ブロック/日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Year and Date
  2013-11-10
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] GlcNAc6ST-2によるMuc2ムチンの硫酸化とその大腸炎防御機能の解析2013
- Author(s)
  西谷麻予、坪井康一郎、飛澤悠葵、今井康之、川島博人
- Organizer
  糖鎖科学中部拠点第11回若手の力フォーラム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] 免疫応答の制御に有用な新規抗フコシル化糖鎖抗体の樹立2013
- Author(s)
  松村龍志、平川城太朗、永井基瑛、今井康之、川島博人
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] ベロ毒素に対する二量体hybrid IgA抗体によるアポトーシス抑制効果2012
- Author(s)
  永野恭子、黒羽子孝太、今井康之他
- Organizer
  第58回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 接触性皮膚炎に対するフタル酸エステル類のアジュバント活性におけるTRP channel の関与2012
- Author(s)
  黒羽子孝太, 佐原百合名, 木村文子, 玉井琢磨, 渡辺達夫, 今井康之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] Development of Shiga toxin-specific Hybrid IgA applicable to in vivo.2012
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  The 5th International Conference on Health and Longevity Sciences
- Place of Presentation
  静岡
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 植物を用いたベロ毒素に対するハイブリッドIgA抗体の発現と性状解析2012
- Author(s)
  中西勝宏、市川史織、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] インフルエンザウイルスHA特異的組換え型IgA抗体による細胞への感染阻害効果2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Production of Shiga toxin-specific recombinant immunoglobulin A in plants.2012
- Author(s)
  今井康之
- Organizer
  The 1st International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] リンパ球ホーミングにおける高内皮細静脈ヘパラン硫酸の機能解析2012
- Author(s)
  坪井康一郎、平川城太朗、關愛実子、今井康之、山口祐、福田穣、川島博人
- Organizer
  糖鎖科学中部拠点第10回若手の力フォーラム
- Place of Presentation
  静岡
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] GlcNAc-6-O-sulfation of colonic mucins protects against experimental colitis in mice.2012
- Author(s)
  Nishitani M, Tsuboi K, Tobisawa Y, Imai Y, and Kawashima H
- Organizer
  The 1sn International Conference on Pharma-Food(ICPF 2012)
- Place of Presentation
  静岡
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] オートファジー関連遺伝子Atg7の大腸特異的欠損マウスにおけるデキストラン硫酸誘発性大腸炎の解析2012
- Author(s)
  小島直記、坪井康一郎、高倉惇、今井康之、小松雅明、川島博人
- Organizer
  平成24年度日本薬学会東海支部例会
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] 植物を用いたベロ毒素に対するハイブリッドIgA抗体の発現と性状解析2012
- Author(s)
  中西勝宏、丹羽康夫、小林裕和、黒羽子孝太、今井康之他
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] FITC 誘導接触性皮膚炎における代替可塑剤のアジュバント活性2012
- Author(s)
  木村文子, 佐原百合名, 黒羽子孝太, 渡辺達夫, 今井康之
- Organizer
  第58回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡市
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] Inhibition of influenza A virus infection to MDCK cells by recombinant IgA specific to hemagglutinin.2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之、他:
- Organizer
  The 20th International Symposium on Macrophage Molecular and Cell Biology2012
- Place of Presentation
  東京
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] In vitroにおける効率的な抗インフルエンザウイルス分泌型IgA抗体の作製2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Neutralization activity of hybrid-IgA plantibody against Shiga toxin 1.2012
- Author(s)
  中西勝宏、黒羽子孝太、今井康之
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] タグ標識J鎖を有するシガ毒素特異的Hybrid IgA抗体の発現と精製2012
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] リンパ球ホーミングにおける高内皮細静脈ヘパラン硫酸の機能解析2012
- Author(s)
  坪井康一郎、平川城太朗、關愛実子、今井康之、山口祐、福田穣、川島博人
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] インフルエンザウイルスHA特異的組換え型IgA抗体による細胞への感染阻害効果2012
- Author(s)
  庄司健太郎、高橋忠伸、黒羽子孝太、鈴木隆、今井康之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 独自の方法論に基づく新規抗フコシル化糖鎖抗体の樹立とその活用2012
- Author(s)
  川島博人、今井康之
- Organizer
  中部乳酸菌研究会
- Place of Presentation
  甲府
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] Essential role of peripheral node addressin in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses2012
- Author(s)
  Ohmichi Y, Hirakawa J, Imai Y, Fukuda M, and Kawashima H.
- Organizer
  Keystone Symposia-Chemokines and Leukocyte Trafficking in Homeostasis and Inflammation
- Place of Presentation
  Breckenridge, Colorado, USA
- Year and Date
  2012-01-10
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] インフルエンザウイルスヘマグルチニン特異的分泌型IgA抗体の作製と解析2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 大腸特異的Atg7欠損マウスにおけるデキストラン硫酸誘発性大腸炎の解析2011
- Author(s)
  坪井康一郎、高倉惇、今井康之、小松雅明、川島博人
- Organizer
  第84回日本生化学会年会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Assembly of dimeric IgA with secretory component expressed in plant system.2011
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  The 19th International Symposium on Macrophage Molecular and Cell Biology 2011
- Place of Presentation
  大阪
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Influenza A型ウイルスHA特異的組み換え型IgA抗体の発現と解析2011
- Author(s)
  庄司健太郎、黒羽子孝太、高橋忠伸、鈴木隆、今井康之
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Novel Anti-Carbohydrate Antibodies Reveal the Cooperative Function of Sulfated N- and O-Glycans in Lymphocyte Homing.2011
- Author(s)
  Hirakawa J, Tsuboi K, Sato K, Kobayashi M, Watanabe S, Takakura A, Imai Y, Ito Y, Fukuda M, Kawashima H
- Organizer
  Keystone Symposia-New Frontiers at the Interface of Immunity and Glycobiology
- Place of Presentation
  Lake Louise, Alberta, Canada
- Year and Date
  2011-03-07
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Novel Anti-Carbohydrate Antibodies Reveal the Cooperative Function of Sulfated N-and O-Glycans in Lymphocyte Homing2011
- Author(s)
  Hirakawa J, Tsuboi K, Sato K, Kobayashi M, Watanabe S, Takakura A, Imai Y, Ito Y, Fukuda M, and Kawashima H.
- Organizer
  Keystone Symposia-New Frontiers at the Interface of Immunity and Glycobiology
- Place of Presentation
  Lake Louise, Alberta, Canada
- Year and Date
  2011-03-08
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Assembly of dimeric IgA with secretory component expressed in plant system.2011
- Author(s)
  K. Nakanishi, K. Kurohane, Y. Niwa, H. Kobayashi, Y. Imai
- Organizer
  The 19th International Symposium of Macrophage Molecular and Cell Biology 2011
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Novel Anti-carbohydrate Antibodies Reveal the Cooperative Function of Sulfated N- and O-Glycans in Lymphocyte Homing2011
- Author(s)
  Hirakawa J, Tsuboi K, Sato K, Imai Y, Kawashima H
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Essential role of peripheral node addressin in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses2011
- Author(s)
  Ohmichi Y, Hirakawa J, Imai Y, Fukuda M, and Kawashima H.
- Organizer
  Keystone Symposia-New Frontiers at the Interface of Immunity and Glycobiology
- Place of Presentation
  Lake Louise, Alberta, Canada
- Year and Date
  2011-03-08
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Novel Anti-carbohydrate Antibodies Reveal the Cooperative Function of Sulfated N-and O-Glycans in Lymphocyte Homing2011
- Author(s)
  Hirakawa J, Tsuboi K, Sato K, Imai Y, and Kawashima H.
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] IgA由来J鎖の植物による発現2011
- Author(s)
  市川史織、中西勝宏、丹羽康夫、小林裕和、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 大腸特異的Atg7欠損マウスにおけるデキストラン硫酸誘発性大腸炎の増悪化2011
- Author(s)
  坪井康一郎、高倉惇、今井康之、小松雅明、川島博人
- Organizer
  第75回日本生化学会中部支部例会
- Place of Presentation
  静岡
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Influenza A型ウイルスHA特異的組み換え型IgA抗体の発現と解析2011
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Lack of TRPM8 involvement in the enhancement of skin sensitization to FITC2011
- Author(s)
  Yurina Sahara, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉市
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] タグ標識J鎖を有するHybrid IgA抗体の発現2011
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] B16メラノーマの肺転移に及ぼすケモカイン強制発現の影響2010
- Author(s)
  加賀正基, 渡部草太, 平川城太朗, 今井康之, 川島博人
- Organizer
  平成22年度日本薬学会東海支部例会
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] ケモカインCXCL10の強制発現によるB16メラノーマの肺転移抑制2010
- Author(s)
  加賀正基、渡部草太、平川城太朗、今井康之、川島博人
- Organizer
  第83回日本生化学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] リンパ節高内皮細静脈におけるケモカインCXCL10の発現とその役割2009
- Author(s)
  渡部草太, 平川城太朗, 加賀正基, 今井康之, 川島博人
- Organizer
  平成21年度日本薬学会東海支部例会
- Place of Presentation
  岐阜
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] 硫酸基転移酵素GlcNAc6ST-2によるマウス大腸ムチンの硫酸化とその大腸炎防御機能2009
- Author(s)
  飛澤悠葵、今井康之、福田穣、川島博人
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] リンパ節高内皮細静脈におけるケモカインCXCL10の発現とその役割2009
- Author(s)
  渡部草太、平川城太朗、加賀正基、今井康之、川島博人
- Organizer
  平成21年度日本薬学会東海支部例会
- Place of Presentation
  四日市
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] スギ花粉アレルゲンCryj1のN-結合型糖鎖による抗原性の修飾2009
- Author(s)
  大槻卓也, 吉岡純一, 小野田貢, 今井康之, 川島博人
- Organizer
  平成21年度日本薬学会東海支部例会
- Place of Presentation
  岐阜
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Essential role of sulfated-glycans in lymphocyte recruitment to nasal-associated lymphoid tissues and allergic immune responses2009
- Author(s)
  Hirakawa J, Ohmichi Y, Imai Y, Fukuda M, and Kawashima H.
- Organizer
  Glycobiology2009
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] スギ花粉アレルゲンCryj1のN-結合型糖鎖による抗原性の修飾2009
- Author(s)
  大槻卓也、吉岡純一、小野田貢、今井康之、川島博人
- Organizer
  平成21年度日本薬学会東海支部例会
- Place of Presentation
  四日市
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] マウスGlcNAc6ST-2によるMuc2ムチンの硫酸化とその大腸炎に対する防御機能の解析2009
- Author(s)
  飛澤悠葵、今井康之、福田穣、川島博人
- Organizer
  第29回日本糖質学会年会
- Place of Presentation
  高山
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] 大腸特異的Atg7欠損マウスにおけるデキストラン硫酸誘発性大腸炎の解析2009
- Author(s)
  高倉惇、坪井康一郎、今井康之、小松雅明、川島博人
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Sulfation of colonic mucins by N-acetylglucosamine-6-O-sulfotransferase-2 and its protective function against colitis in mice2009
- Author(s)
  Tobisawa Y, Imai Y, Fukuda M, and Kawashima H.
- Organizer
  Glycobiology2009
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Lymphocyte recruitment to nasal-associated lymphoid tissues is regulated by two sulfotransferases2009
- Author(s)
  Hirakawa J, Ohmichi Y, Imai Y, Fukuda M, Kawashima H.
- Organizer
  2008 International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Lymphocyte recruitment to nasal-associated lymphoid tissues is regulated by two sulfotransferases2009
- Author(s)
  Hirakawa J, Ohmichi Y, Imai Y, Fukuda M, and Kawashima H.
- Organizer
  2008 International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  Kanazawa, Japan
- Data Source
  KAKENHI-PROJECT-21390023
[Presentation] Dendritic cell trafficking and TRPV1 receptors of sensory neurons2007
- Author(s)
  Yasuyuki Imai
- Organizer
  16th International Symposium on Molecular Cell Biology of Macrophages 2007
- Place of Presentation
  静岡市
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-18659033
[Presentation] Separation and characterization of intact dimeric form of Shiga toxin 1-specific hybrid-IgA plantibodies expressed in Arabidopsis thaliana.
- Author(s)
  Shogo Tsuruta, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 免疫応答の制御に有用な新規抗フコシル化糖鎖抗体の樹立
- Author(s)
  松村龍志、今井康之、川島博人
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] 6-スルホシアリルルイスX特異的モノクローナル抗体の樹立とその免疫抑制能の検討
- Author(s)
  松浦寛明、松村龍志、永井基瑛、平川城太朗、今井康之、川島博人
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] オートファジー関連遺伝子Atg7は腸内細菌叢を制御し大腸炎を抑制する
- Author(s)
  坪井康一郎，西谷麻予，今井康之，小松雅明，川島博人
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] Development of Shiga toxin-specific hybrid IgA-tag: focus on the purification process.
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Yasuyuki Imai
- Organizer
  Sixth Annual Protein & Antibody engineering Summit
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] In vitro formation of a secretory hybrid IgA specific for influenza A virus hemmagglutinin.
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 新規抗フコシル化糖鎖抗体による炎症反応抑制効果の検討
- Author(s)
  松村龍志、平川城太朗、石原陽子、今井康之、川島博人
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] Purification of dimeric hybrid-IgA expressed in plants and mammalian cells using thiophilic adsorption chromatography.
- Author(s)
  Shogo Tsuruta, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  The 2nd International Conference on Pharma and Food
- Place of Presentation
  日本平ホテル、静岡市
- Year and Date
  2014-11-05 – 2014-11-06
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] リンパ球ホーミングにおける高内皮細静脈ヘパラン硫酸の機能解析
- Author(s)
  坪井康一郎、今井康之、川島博人
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-24390018
[Presentation] Comparison of the hybrid IgA expressed in plant and mammalian cell systems.
- Author(s)
  Katsuhiro Nakanishi, Shogo Tsuruta, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  Sixth Annual Protein & Antibody engineering Summit
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25670063

1. KUROHANE Kohta (90333525)

# of Collaborated Projects : 8results

# of Collaborated Products : 77results
2. YAMAMOTO Kazuo (20174782)

# of Collaborated Projects : 7results

# of Collaborated Products : 0results
3. TSUJI Tsutomu (00143503)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
4. IRIMURA Tatsuro (80092146)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
5. KAWASHIMA Hiroto (50260336)

# of Collaborated Projects : 3results

# of Collaborated Products : 46results
6. WATANABE Tatsuo (10210915)

# of Collaborated Projects : 3results

# of Collaborated Products : 8results
7. KOBAYASHI Hirokazu (80170348)

# of Collaborated Projects : 3results

# of Collaborated Products : 20results
8. NIWA Yasuo (00222191)

# of Collaborated Projects : 3results

# of Collaborated Products : 20results
9. MURAI Toshiyuki (20311756)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. OSAWA Toshiaki (40012603)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
11. KOBAYASHI Motohiro (00362137)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
12. MASUDA Jun-ishi (70173747)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. TSUIJI Makoto (90302611)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. TOYOSHIMA Satoshi (40092283)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. TAKAYAMA Hiroo

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. YAMAOKA Takashi

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. HIGUCHI Masahiro

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. MANABE Kei

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
19. KONISHI Hideyuki

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
20. NAKANISHI Katsuhiro

# of Collaborated Projects : 1results

# of Collaborated Products : 14results
21. AKIMOTO Yoshihiro

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
22. KAWAKAMI Hayato

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
23. MATSUBARA Sachie

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
24. Sumalee Panthong

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. Arunporn Itharat

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. HIRAKAWA Jotaro

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
27. 小松雅明

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
28. 高橋忠伸

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

IMAI Yasuyuki 今井 康之

Research Projects

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Co-Researchers

Studies on adjuvant chemicals predicted by activation of a nociceptive receptor TRPA1Principal Investigator

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Studies on the efficacy of toxin neutralization and safety of Shiga toxin-specific secretory IgA type plantibody produced by practical plantsPrincipal Investigator

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Mucosal surface defense by edible IgA produced by plantsPrincipal Investigator

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Adjuvant effect of chemicals on contact hypersensitivity through transient receptor potential channelsPrincipal Investigator

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Expression of secretory immunoglobulin A in lettuce suitable for the production of therapeutic antibodies in plantfactory.Principal Investigator

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Adjuvant effect mechanism on contact sensitization through nociceptive receptorsPrincipal Investigator

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接触感作促進作用を有する化学物質の侵害刺激受容チャネルに対する効果Principal Investigator

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Production of IgA using nasal associated lymphoid tissues toward development of therapeutic antibodies for oral administration.Principal Investigator

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細菌由来の糖鎖認識分子に対抗した宿主粘膜免疫系の応答に関する研究Principal Investigator

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Development of functional IgA antibodies against carbohydrate recognition activity of Vero toxin and their application to treatment.Principal Investigator

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抗腫瘍性マクロファージの腫瘍認識機構。C-タイプレクチンの関与Principal Investigator

Principal Investigator

IMAI Yasuyuki 今井康之