KUROHANE Kohta 黒羽子孝太

Researcher Number	90333525
Other IDs
Affiliation *help	2014 – 2018 : 静岡県立大学, 薬学部, 講師 2006 – 2013 : 静岡県立大学, 薬学部, 助教 2004 – 2005 : 静岡県立大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Environmental and hygienic pharmacy Except Principal Investigator Environmental pharmacy / Environmental and hygienic pharmacy / Biological pharmacy
Keywords	Principal Investigator ワクチン / 感染症 / 薬学 / 免疫学 / ベロ毒素 / リポソーム / IgA / 粘膜免疫 / 腸管出血 / 性大腸菌 / 薬物送達学 / 微生物 / 分泌片 … More Except Principal Investigator … More

抗ベロ毒素IgA抗体の構築を目指したMHC結合性ペプチド含有ワクチンの開発Principal InvestigatorOngoing
- Principal Investigator
  
  黒羽子孝太
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Studies on adjuvant chemicals predicted by activation of a nociceptive receptor TRPA1
- Principal Investigator
  
  Imai Yasuyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Studies on the efficacy of toxin neutralization and safety of Shiga toxin-specific secretory IgA type plantibody produced by practical plants
- Principal Investigator
  
  今井康之
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Mucosal surface defense by edible IgA produced by plants
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  University of Shizuoka
Adjuvant effect of chemicals on contact hypersensitivity through transient receptor potential channels
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Expression of secretory immunoglobulin A in lettuce suitable for the production of therapeutic antibodies in plantfactory.
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Production of secretory IgA against Shiga-like toxin B subunit using liposomes entrapping MHC-binding peptidesPrincipal Investigator
- Principal Investigator
  
  KUROHANE Kohta
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Adjuvant effect mechanism on contact sensitization through nociceptive receptors
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Induction of mucosal immunity using liposomes entrapping MHC-binding peptidesPrincipal Investigator
- Principal Investigator
  
  KUROHANE Kohta
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
接触感作促進作用を有する化学物質の侵害刺激受容チャネルに対する効果
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Shizuoka
Production of IgA using nasal associated lymphoid tissues toward development of therapeutic antibodies for oral administration.
- Principal Investigator
  
  IMAI Yasuyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2005 Other

All Journal Article Presentation

[Journal Article] Protection of human colon cells from Shiga toxin by plant-based recombinant secretory IgA2017
- Author(s)
  Katsuhiro Nakanishi, Shota Morikane, Shiori Ichikawa, Kohta Kurohane, Yasuo Niwa, Yoshihiro Akimoto, Sachie Matsubara, Hayato Kawakami, Hirokazu Kobayashi, Yasuyuki Imai
- Journal Title
  
  Sci. Rep.
  
  Volume : 7 Pages : 45843-45843
- DOI
  10.1038/srep45843
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04660
[Journal Article] Dibutyl maleate and dibutyl fumarate enhance contact sensitization to fluorescein isothiocyanate in mice.2016
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Wakana Suzuki, Erina Ogawa, Kamiyu Kobayashi, and Yasuyuki Imai
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume : 39 Pages : 272-277
- DOI
  10.1248/bpb.b15-00683
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14990
[Journal Article] Adjuvant effect of an alternative plasticizer diisopropyl adipate on a contact hypersensitivity mouse model: link with sensory ion channel TRPA1 activation.2015
- Author(s)
  Kohta Kurohane, Ayako Kimura, Rie Terasawa, Yurina Sahara, Kamiyu Kobayashi, Wakana Suzuki, Takeshi Matsuoka, Tatsuo Watanabe, and Yasuyuki Imai:
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume : 38 Pages : 1054-1062
- DOI
  10.1248/bpb.b15-00199
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14990
[Journal Article] Lack of impact of high dietary vitamin A on T helper 2-dependent contact hypersensitivity to fluorescein isothiocyanate in mice.2015
- Author(s)
  Chie Kobayashi, Kohta Kurohane, and Yasuyuki Imai
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume : 38 Pages : 1827-1830
- DOI
  10.1248/bpb.b15-00534
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14990
[Journal Article] Recombinant IgA specific for influenza A virus hemagglutinin: production, functional analysis and formation of secretory IgA2015
- Author(s)
  Kentaro Shoji, Tadanobu Takahashi, Kohta Kurohane, Koki Iwata, Takeshi Matsuoka, Shogo Tsuruta, Takatomo Sugino, Masaki Miyake, Takashi Suzuki, Yasuyuki Imai
- Journal Title
  
  Viral Immunol.
  
  Volume : 28, Pages : 170-178
- DOI
  10.1089/vim.2014.0098
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670063, KAKENHI-PROJECT-15H05644, KAKENHI-PROJECT-26670064
[Journal Article] Plantibodyの臨床応用2014
- Author(s)
  中西勝宏、黒羽子孝太、今井康之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume : 62 Pages : 192-197
- Data Source
  KAKENHI-PROJECT-25670063
[Journal Article] Stable expression and characterization of monomeric and dimeric recombinant hybrid-IgG/IgA immunoglobulins specific for Shiga toxin.2014
- Author(s)
  Iwata K, Kurohane K, Nakanishi K, Miyake M, Imai Y
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume : 37 Pages : 1510-1515
- DOI
  10.1248/bpb.b14-00323
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J10915, KAKENHI-PROJECT-25670063
[Journal Article] Shiga toxin-induced apoptosis is more efficiently inhibited by dimeric recombinant hybrid-IgG/IgA immunoglobulins than by the parental IgG monoclonal antibodies.2014
- Author(s)
  Kurohane K, Nagano K, Nakanishi K, Iwata K, Miyake M, Imai Y
- Journal Title
  
  Virulence
  
  Volume : 5 Pages : 819-824
- DOI
  10.4161/21505594.2014.973804
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J10915, KAKENHI-PROJECT-25670063
[Journal Article] Production of hybrid-IgG/IgA plantibodies with neutralizing activity against Shiga toxin 12013
- Author(s)
  Nakanishi K, Narimatsu S, Ichikawa S, Tobisawa Y, Kurohane K, Niwa Y, Kobayashi H, Imai Y
- Journal Title
  
  PLoS ONE
  
  Volume : 8
- DOI
  10.1371/journal.pone.0080712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10915, KAKENHI-PROJECT-25660008, KAKENHI-PROJECT-25670063
[Journal Article] Lack of transient receptor potential melastatin 8 activation by phthalae esters that enhance contact hypersensitivity in mice.2013
- Author(s)
  Kohta Kurohane, Yurina Sahara, Ayako Kimura, Masataka Narukawa, Tatsuo Watanabe, Takashi Daimon, Yasuyuki Imai
- Journal Title
  
  Toxicol. Lett.
  
  Volume : 217 Pages : 192-196
- DOI
  10.1016/j.toxlet.2012.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390031
[Journal Article] High dose dietary pyridoxine induces T-helper type 1 polarization and decreases contact hypersensitivity response to fluorescein isothiocyanate in mice2012
- Author(s)
  Chie Kobayashi, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume : 35 Pages : 532-538
- URL
  https://www.jstage.jst.go.jp/article/bpb/35/4/35_4_532/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390031
[Journal Article] Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model.2012
- Author(s)
  Takahiro Shiba, Takuma Tamai, Yurina Sahara, Kohta Kurohane, Tatsuo Watanabe, Yasuyuki Imai
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume : 264 Pages : 370-376
- DOI
  10.1016/j.taap.2012.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390031
[Journal Article] Establishment of recombinant hybrid-IgG/IgA immunoglobulin specific for Shiga toxin.2011
- Author(s)
  Yuki Tobisawa, Takashi Maruyama, Takashi Tanikawa, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Scand. J. Immunol.
  
  Volume : 76 Pages : 574-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659067
[Journal Article] Phthalate esters reveal skin-sensitizing activity of phenethyl isothiocyanate in mice.2010
- Author(s)
  Tomoko Matsuda, Takashi Maruyama, Hiromi Iizuka, Ayumi Kondo, Takuma Tamai, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Food Chem. Toxicol 48
  
  Pages : 1704-1708
- Data Source
  KAKENHI-PROJECT-20390041
[Journal Article] Di-(2-ethylhexyl) phthalate enhances skin sensitization to isocyanate haptens in mice.2010
- Author(s)
  Tomoko Matsuda, Kohta Kurohane, Yasuyuki Imai
- Journal Title
  
  Toxicol. Lett 192
  
  Pages : 97-100
- Data Source
  KAKENHI-PROJECT-20390041
[Journal Article] TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity.2009
- Author(s)
  Takahiro Shiba, Takashi Maruyama, Kohta Kurohane, Yusaku Iwasaki, Tatsuo Watanabe, Yasuyuki Imai
- Journal Title
  
  J. Neuroimmunol 207
  
  Pages : 66-74
- Data Source
  KAKENHI-PROJECT-20390041
[Journal Article] Facilitated production of secretory IgA against Shiga toxin B subunits by intranasal application of antigen-coated polystyrene microspheres.2005
- Author(s)
  Kohta Kurohane
- Journal Title
  
  Microbiol.Immunol. 49
  
  Pages : 149-154
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590055
[Journal Article] Facilitated production of secretory IgA against Shiga toxin B subunits by intranasal application of antigen-coated polystyrene microspheres.2005
- Author(s)
  Kohta Kurohane, Chie Kobayashi, Yasuyuki Imai
- Journal Title
  
  Microbiol.Immunol. 49
  
  Pages : 149-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590055
[Journal Article] Production of IgA monoclonal antibody against Shiga toxin binding subunits employing nasal-associated lymphoid tissue.2005
- Author(s)
  Yasuyuki Imai, Tomoyuki Ishikawa, Takashi Tanikawa, Hiroki Nakagami, Takeshi Maekawa, Kohta Kurohane
- Journal Title
  
  J.Immunol.Methods 302
  
  Pages : 125-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590055
[Presentation] FITC誘導接触性皮膚炎マウスモデルにおけるFITC特異的抗体産生2018
- Author(s)
  黒羽子孝太、遠藤由貴奈、今井康之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08344
[Presentation] 植物由来組換え型分泌片を活用した抗原特異的分泌型IgAの構築と消化酵素抵抗性の付与2018
- Author(s)
  菊地祐希、松田弥奈美、森兼捷太、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 1型線毛に結合するIgA型イムノアドヘシンの作製2018
- Author(s)
  中西勝宏、黒羽子孝太、今井康之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Enhancing effect of an alternative plasticizer on a contact hypersensitivity mouse model: involvement of TRPA1 activation2017
- Author(s)
  Yasuyuki Imai, Kohta Kurohane, Ayako Kimura, Rie Terasawa, Yurina Sahara, Kamiyu Kobayashi, Wakana Suzuki, Takeshi Matsuoka, Tatsuo Watanabe
- Organizer
  The 12th China-Japan Symposium on Health Sciences
- Place of Presentation
  Hangzhou, China
- Year and Date
  2017-02-10
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] FITCを用いた経皮免疫による抗FITC抗体の誘導2017
- Author(s)
  遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2017
- Data Source
  KAKENHI-PROJECT-16K08344
[Presentation] Differential effects of high dose dietary vitamin A and B6 on contact hypersensitivity response in mice2017
- Author(s)
  Kohta Kurohane, Chie Kobayashi, Yasuyuki Imai
- Organizer
  The 12th China-Japan Symposium on Health Sciences
- Place of Presentation
  Hangzhou, China
- Year and Date
  2017-02-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Adjuvant effect of short chain fatty acid glycerol esters during sensitization phase of contact hypersensitivity2017
- Author(s)
  Kota Sekiguchi, Erina Ogawa, Hideyuki Konishi, Kei Manabe, Yukina Endo, Masato Tsutumi, Narumi Mochizuki, Kohta Kurohane, Yasuyuki Imai
- Organizer
  The 12th China-Japan Symposium on Health Sciences
- Place of Presentation
  Hangzhou, China
- Year and Date
  2017-02-10
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 短鎖・中鎖脂肪酸を有するトリグリセリドによる接触性皮膚炎の感作促進作用2017
- Author(s)
  関口皓太、小川衿菜、堤正人、望月成美、遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] FITC誘導接触性皮膚炎における皮膚感作促進作用：パラベンの評価2017
- Author(s)
  遠藤由貴奈、松岡毅、鈴木若菜、小川衿菜、関口皓太、黒羽子孝太、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 植物で作製した小胞体保留シグナル付加分泌片の糖鎖解析2017
- Author(s)
  梶原優佳、森兼捷太、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 分泌型ハイブリッドIgA植物抗体によるベロ毒素のヒト腸管上皮細胞に対する細胞毒性の中和効果の検討2017
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 植物で作製した分泌片を活用した分泌型IgAの消化酵素抵抗性に関する研究2017
- Author(s)
  松田弥奈美、森兼捷太、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Transient receptor potential (TRP) チャネル活性化を指標としたアジュバント物質の探索2017
- Author(s)
  黒羽子孝太
- Organizer
  USフォーラム2017
- Place of Presentation
  静岡
- Year and Date
  2017-04-20
- Data Source
  KAKENHI-PROJECT-16K08344
[Presentation] Production of secretory hybrid-IgG/IgA in plant expression system.2017
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 小胞体保留シグナルを利用した分泌型IgAの植物での生産性向上2016
- Author(s)
  森兼捷太、細川奈緒、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] ベロ毒素に対する分泌型ハイブリッドIgAの植物での産生と細胞内局在の解析2016
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、松原幸枝、秋元義弘、川上速人、小林裕和、今井康之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 接触性皮膚炎におけるTributyrinの感作促進作用2016
- Author(s)
  小川衿菜、関口皓太、遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋市
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 短鎖脂肪酸グリセロールエステルによる接触性皮膚炎の感作促進作用2016
- Author(s)
  関口皓太、小川衿菜、小西英之、眞鍋　敬、遠藤由貴奈、黒羽子孝太、今井康之
- Organizer
  フォーラム2016　衛生薬学・環境トキシコロジー
- Place of Presentation
  東京都
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 代替可塑剤の免疫促進作用とThymic Stromal Lymphopoietin産生の関係2016
- Author(s)
  関口皓太、鈴木若菜、小川衿菜、黒羽子孝太、今井康之
- Organizer
  日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋市
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Establishment of secretory hybrid IgA with binding to Shiga toxin 1 binding subunit in lettuce2016
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  第21回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Immunomodulation through transient receptor potential (TRP) channels2016
- Author(s)
  Yasuyuki Imai, Kohta Kurohane, Sumalee Panthong, Arunporn Itharat
- Organizer
  20th World Congress on Clinical Nutrition
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2016-12-14
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] 接触性皮膚炎におけるマレイン酸ジブチルのアジュバント作用2016
- Author(s)
  黒羽子孝太、松岡　毅、鈴木若菜、小川衿菜、小林香美結、今井康之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Hybrid IgA expressed in Arabidopsis is localized in the protein body-like structure in the leaves2015
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Sachie Matsubara, Yoshihiro Akimoto, Hayato Kawakami, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  植物電子顕微鏡ワークショップ2015
- Place of Presentation
  横浜
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Intrarectal administration of Shiga toxin 1 injures mouse colonic epithelial cells2015
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 機能解析を目指した植物発現hybrid IgA抗体の精製2015
- Author(s)
  杉野嵩朋、中西勝宏、鶴田昌吾、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部　合同学術大会2015
- Place of Presentation
  名古屋
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] Production of secretory component-KDEL in Arabidopsis thaliana2015
- Author(s)
  Nao Hosokawa, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15H04660
[Presentation] 代替可塑剤によるFITC誘導性接触性皮膚炎の増悪化2015
- Author(s)
  黒羽子孝太、松岡　毅、小林香美結、鈴木若菜、小川衿菜、渡辺達夫、今井康之
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Adjuvant effect of dibutyl maleate in an FITC-induced contact hypersensitibvity mouse model2015
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Wakana Suzuki, Kamiyu Kobayashi, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] The role of thymic stromal lymphopoietin in FITC-induced contact hypersensitivity2015
- Author(s)
  Wakana Suzuki, Kamiyu Kobayashi, Takeshi Matsuoka, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K14990
[Presentation] Development of neutralizing hybrid-IgG/IgA specific for Shiga toxin.2014
- Author(s)
  Kohta Kurohane, Katsuhiro Nakanishi, Yasuyuki Imai
- Organizer
  11th Japan-China International Symposium on Health Sciences
- Place of Presentation
  静岡県立大学、静岡市
- Year and Date
  2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 静脈内投与により胆汁中に分泌されたShiga toxin特異的hybrid IgAの毒素中和血清と分泌経路の解析2014
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス、熊本市
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] ベロ毒素に対するIgA植物抗体をめざして2013
- Author(s)
  今井康之、中西勝宏、黒羽子孝太、丹羽康夫、小林裕和
- Organizer
  第25回微生物シンポジウム　～ヒトの健康と微生物～
- Place of Presentation
  静岡県立大学、静岡市
- Invited
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Production of dimeric hybrid-IgA specific for Shiga toxin 1 in Arabidopsis thaliana.2013
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  Plant-based Vaccines, Antibodies & Biologics
- Place of Presentation
  University of Verona, Verona, Italy
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] 接触性皮膚炎の感作過程における代替可塑剤のアジュバント作用機構2013
- Author(s)
  寺澤里恵、木村文子、小林香美結、鈴木若菜、松岡　毅、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック／日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] 接触性皮膚炎の感作過程における代替可塑剤のアジュバント作用機構2013
- Author(s)
  寺澤里恵, 木村文子, 小林香美結, 鈴木若菜, 松岡毅, 黒羽子孝太, 今井康之
- Organizer
  日本病院薬剤師会東海ブロック/日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Year and Date
  2013-11-10
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] 植物で作製した分泌片の糖鎖解析2013
- Author(s)
  荒木　瞳、中西勝宏、鶴田昌吾、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本病院薬剤師会東海ブロック／日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿医療科学大学白子キャンパス、鈴鹿市
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Production of secretory hybrid-IgA specific for Shiga toxin 1 in lettuce.2013
- Author(s)
  Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] インフルエンザウイルスHA特異的組換え型IgA抗体による細胞への感染阻害効果2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 植物を用いたベロ毒素に対するハイブリッドIgA抗体の発現と性状解析2012
- Author(s)
  中西勝宏、丹羽康夫、小林裕和、黒羽子孝太、今井康之他
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] ベロ毒素に対する二量体hybrid IgA抗体によるアポトーシス抑制効果2012
- Author(s)
  永野恭子、黒羽子孝太、今井康之他
- Organizer
  第58回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Inhibition of influenza A virus infection to MDCK cells by recombinant IgA specific to hemagglutinin.2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之、他:
- Organizer
  The 20th International Symposium on Macrophage Molecular and Cell Biology2012
- Place of Presentation
  東京
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] タグ標識J鎖を有するシガ毒素特異的Hybrid IgA抗体の発現と精製2012
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] FITC 誘導接触性皮膚炎における代替可塑剤のアジュバント活性2012
- Author(s)
  木村文子, 佐原百合名, 黒羽子孝太, 渡辺達夫, 今井康之
- Organizer
  第58回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡市
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] 接触性皮膚炎に対するフタル酸エステル類のアジュバント活性におけるTRP channel の関与2012
- Author(s)
  黒羽子孝太, 佐原百合名, 木村文子, 玉井琢磨, 渡辺達夫, 今井康之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] 接触性皮膚炎に対するフタル酸エステル類のアジュバント活性におけるTRP channelの関与2012
- Author(s)
  黒羽子孝太
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] インフルエンザウイルスHA特異的組換え型IgA抗体による細胞への感染阻害効果2012
- Author(s)
  庄司健太郎、高橋忠伸、黒羽子孝太、鈴木隆、今井康之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 植物を用いたベロ毒素に対するハイブリッドIgA抗体の発現と性状解析2012
- Author(s)
  中西勝宏、市川史織、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] インフルエンザウイルスヘマグルチニン特異的分泌型IgA抗体の作製と解析2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Neutralization activity of hybrid-IgA plantibody against Shiga toxin 1.2012
- Author(s)
  中西勝宏、黒羽子孝太、今井康之
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Development of Shiga toxin-specific Hybrid IgA applicable to in vivo.2012
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  The 5th International Conference on Health and Longevity Sciences
- Place of Presentation
  静岡
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] In vitroにおける効率的な抗インフルエンザウイルス分泌型IgA抗体の作製2012
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] タグ標識J鎖を有するHybrid IgA抗体の発現2011
- Author(s)
  松岡毅、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Influenza A型ウイルスHA特異的組み換え型IgA抗体の発現と解析2011
- Author(s)
  庄司健太郎、黒羽子孝太、今井康之他
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Assembly of dimeric IgA with secretory component expressed in plant system.2011
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  The 19th International Symposium on Macrophage Molecular and Cell Biology 2011
- Place of Presentation
  大阪
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Lack of TRPM8 involvement in the enhancement of skin sensitization to FITC2011
- Author(s)
  Yurina Sahara, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉市
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23390031
[Presentation] Assembly of dimeric IgA with secretory component expressed in plant system.2011
- Author(s)
  K. Nakanishi, K. Kurohane, Y. Niwa, H. Kobayashi, Y. Imai
- Organizer
  The 19th International Symposium of Macrophage Molecular and Cell Biology 2011
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Influenza A型ウイルスHA特異的組み換え型IgA抗体の発現と解析2011
- Author(s)
  庄司健太郎、黒羽子孝太、高橋忠伸、鈴木隆、今井康之
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] 植物で発現した分泌片(SC)を用いた分泌型IgAの構築2011
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] 植物で発現した分泌片(SC)を用いた分泌型lgAの構築2011
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] IgA由来J鎖の植物による発現2011
- Author(s)
  市川史織、中西勝宏、丹羽康夫、小林裕和、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23659067
[Presentation] Expression of IgA plantibody against carbohydrate binding subunits of Shiga toxin.2010
- Author(s)
  K.Nakanishi, K.Iwata, K.Kurohane, et al
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] ベロ毒素に対するIgA型植物抗体の発現2010
- Author(s)
  中西勝宏、黒羽子孝太、丹羽康夫、小林裕和、今井康之
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] 組換え型分泌片(SC)の安定発現株の構築および性状解析2010
- Author(s)
  笹沼康一、岩田皓生、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック/日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] IgA plantibody against carbohydrate binding subunits of Shiga toxin.2010
- Author(s)
  Katsuhiro Nakanishi, Koki Iwata, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] Poly Ig receptor発現上皮細胞株の構築および機能解析2010
- Author(s)
  出口彩、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック/日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] Stx1Bに対する組み換え型キメラIgA抗体の発現とその性状解析2009
- Author(s)
  岩田皓生、飛澤悠葵、黒羽子孝太、今井康之
- Organizer
  日本病院薬剤師会東海ブロック/日本薬学会東海支部合同学術大会2009
- Place of Presentation
  三重
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-21790086
[Presentation] Yasuyuki Imai Liposomalization of recombinant Shiga toxin 1B augmented production of Stx1B-specific secretory IgA on various mucosal tissues2008
- Author(s)
  Kohta Kurohane, Ai Fukaya,
- Organizer
  11th Liposomes Research Days Conference
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19790067
[Presentation] リポソームに内封した志賀毒素Bサブユニットの経鼻免疫による抗原特異的分泌型IgAの産生促進と維持2008
- Author(s)
  深谷愛、黒羽子孝太、今井康之
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19790067
[Presentation] Liposomalization of recombinant Shiga toxin 1B augmented production of Stx1B-snecific secretory IgA on various mucosal tissues2008
- Author(s)
  Kohta Kurohane, Ai Fukaya, Yasuvuki Imai
- Organizer
  11th Liposomes research Days Conference
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790067
[Presentation] 経鼻投与リポソームを用いたベロ毒素に対する腸管内分泌型IgA産生の誘導2008
- Author(s)
  深谷愛、黒羽子孝太、今井康之
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19790067
[Presentation] In vitro formation of a secretory hybrid IgA specific for influenza A virus hemmagglutinin.
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Separation and characterization of intact dimeric form of Shiga toxin 1-specific hybrid-IgA plantibodies expressed in Arabidopsis thaliana.
- Author(s)
  Shogo Tsuruta, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館、京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Comparison of the hybrid IgA expressed in plant and mammalian cell systems.
- Author(s)
  Katsuhiro Nakanishi, Shogo Tsuruta, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai
- Organizer
  Sixth Annual Protein & Antibody engineering Summit
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Development of Shiga toxin-specific hybrid IgA-tag: focus on the purification process.
- Author(s)
  Takeshi Matsuoka, Kohta Kurohane, Yasuyuki Imai
- Organizer
  Sixth Annual Protein & Antibody engineering Summit
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25670063
[Presentation] Purification of dimeric hybrid-IgA expressed in plants and mammalian cells using thiophilic adsorption chromatography.
- Author(s)
  Shogo Tsuruta, Katsuhiro Nakanishi, Kohta Kurohane, Yasuyuki Imai
- Organizer
  The 2nd International Conference on Pharma and Food
- Place of Presentation
  日本平ホテル、静岡市
- Year and Date
  2014-11-05 – 2014-11-06
- Data Source
  KAKENHI-PROJECT-25670063

1. IMAI Yasuyuki (80160034)

# of Collaborated Projects : 8results

# of Collaborated Products : 77results
2. WATANABE Tatsuo (10210915)

# of Collaborated Projects : 3results

# of Collaborated Products : 8results
3. KOBAYASHI Hirokazu (80170348)

# of Collaborated Projects : 2results

# of Collaborated Products : 10results
4. NIWA Yasuo (00222191)

# of Collaborated Projects : 2results

# of Collaborated Products : 10results
5. MANABE Kei

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
6. KONISHI Hideyuki

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
7. Sumalee Panthong

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. Arunporn Itharat

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 高橋忠伸

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

KUROHANE Kohta 黒羽子 孝太

Research Projects

Research Products

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抗ベロ毒素IgA抗体の構築を目指したMHC結合性ペプチド含有ワクチンの開発Principal InvestigatorOngoing

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Production of secretory IgA against Shiga-like toxin B subunit using liposomes entrapping MHC-binding peptidesPrincipal Investigator

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Induction of mucosal immunity using liposomes entrapping MHC-binding peptidesPrincipal Investigator

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[Journal Article] Protection of human colon cells from Shiga toxin by plant-based recombinant secretory IgA2017

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[Journal Article] Dibutyl maleate and dibutyl fumarate enhance contact sensitization to fluorescein isothiocyanate in mice.2016

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[Journal Article] Adjuvant effect of an alternative plasticizer diisopropyl adipate on a contact hypersensitivity mouse model: link with sensory ion channel TRPA1 activation.2015

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[Journal Article] Lack of impact of high dietary vitamin A on T helper 2-dependent contact hypersensitivity to fluorescein isothiocyanate in mice.2015

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KUROHANE Kohta 黒羽子孝太