NOSHIRO Mitsuhide 能城光秀

… Alternative Names

能代光秀ノシロミツヒデ

能城光秀ノシロミツヒデ

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Researcher Number	00144858
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2013: 広島大学, 医歯薬保健学研究院, 准教授 2012: 広島大学, 大学院・医歯薬保健学研究院, 准教授 2010 – 2011: 広島大学, 大学院・医歯薬学総合研究科, 准教授 2008: Hiroshima University, 医歯薬学総合研究科, 准教授 2007 – 2008: Hiroshima University, 大学院・医歯薬学総合研究科, 准教授 … More 2006: 広島大学, 大学院医歯薬学総合研究科, 助教授 2002 – 2005: Hiroshima University Graduate School of Biomedical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 1994 – 2001: 広島大学, 歯学部, 助教授 1991 – 1992: 広島大学, 歯学部, 助教授 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Environmental physiology (including Physical medicine and Nutritional physiology) / 代謝生物化学 Except Principal Investigator Functional basic dentistry / Functional basic dentistry / 小児・社会系歯学
Keywords	Principal Investigator DEC2 / DEC1 / 軟骨細胞培養 / クローニング / 軟骨基質 / コラーゲン / 軟骨細胞 / コレステロール / chondrocyte / cAMP … More / RBP / RGD-CAP / 概日リズム / 時計遺伝子 / 細胞接着 / インテグリン認識部位 / BMP / circadian rhythm / stem cell / statin / Cholesterol / 日内リズム / 骨形成因子 / 幹細胞 / スタチン / hedgehog / PTH / retinoic acid / ヘッジホッグ / 副甲状腺ホルモン / レチノイン酸 / cell adhesion / chondrocyte culture / cloning / cartelage matrix / integrin / collagen / cDNAクローニング / 細胞外基質 / インテグリン / 遺伝子発現 / 核内受容体 / 脂肪分化 / 脂質代謝 / CYP51 / CYP8B / CYP7A / Cyp51 / Cyp8b / ステロール / Cyp7a / Dec2 / Dec1 / Cyp7a, Dec1, Dec2 / 軟骨組織培養 / アンチセンスオリゴマー / RT-PCR / チトクロムP450 / 7α水酸化酵素 / 胆汁酸合成 … More Except Principal Investigator DEC1 / chondrocyte / MTF / 軟骨細胞 / PTH / ノックアウトマウス / DEC2 / cartilage / collagen / 軟骨 / 接着因子 / コラーゲン / 転写因子 / differentiation / clock mutant / transgenic mice / knockout mice / circadian rhythms / 軟骨分化 / clock遺伝子 / トランスジェニックマウス / 日内リズム / regeneration / mesenchymal stem cells / transcription / 骨軟骨再生 / 由来間葉系細胞 / Indian hedgehog / retinoic adic / PTHrp / レチノール結合タンパク / 副甲状腺ホルモン様ペプチド / 副甲状腺ホルモン / biomatenal / integrin / RGD-CAP / CMP / 線維芽細胞 / 生体材料 / インテグリン / RGD / 繊維芽細胞 / transferrin / Endochondral bone formation / 軟骨細胞培 / プロテオグリカン合成 / コンカナバリンA / ハイブリドーマ / モノクローナル / コンドロトランスフェリン / トランスフェリン / 軟骨特異的発現 / inflammation / amiroid / interleukin-1 / osteonectin / 炎症 / インターロイキン-1 / アミロイド / オステオネクチン / 骨 / matrix metalloproteinase / adhesion / TGF-B / RGD配列 / cDNA / PCR / MMP / 2012/12/01 / ﾉｯｸｱｳﾄﾏｳｽ / 時計遺伝子 / 血圧 / 変異マウス / 概日リズム / エストロゲンレセプタ- / 分子生物学 / 歯周疾患 / PCR法 / エストロゲンレセプター / 熱ショック蛋白質 Less

The molecular mechanism by which transcriptional factor DEC1 modulates circadian rhythms of blood pressure.
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Study on the roles of DEC1 and DEC2 in the rhythmic regulation of lipid metabolism.Principal Investigator
- Principal Investigator
  
  NOSHIRO Mitsuhide
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Hiroshima University
Regulatory mechanism of rhythmic expression of cholesterol metabolizing enzymes by clock-related gene DEC1 and DEC2Principal Investigator
- Principal Investigator
  
  NOSHIRO Mitsuhide
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Hiroshima University
骨・軟骨の分子時計系の解明とその標的遺伝子の同定
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Molecular clock and bone metabolism : stimulation of osteoblast and chondrocyte differentiation by novel clock genes
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
Study on the effects of statin on growth and differentiation of cartilagePrincipal Investigator
- Principal Investigator
  
  NOSHIRO Mitsuhide
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
Regeneration of cartilage and bone by transplantation of autologous cells transfected with chondrocyte-inducible genes
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
Regulation and function of retinol binding protein in cartilagePrincipal Investigator
- Principal Investigator
  
  NOSHIRO Mitsuhide
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
Role of PTH and PTH-related peptide in skeletal development
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Biomaterial having active sites of collagen-binding adhesion molecules (CMP and RGD-CAP)
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Expression and function of RGD-CAP conatining RGD-motif in cartilagePrincipal Investigator
- Principal Investigator
  
  NOSHIRO Mitsuhide
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Grant-in-Aid for Scientific Research (C)(2)
軟骨組織におけるRGD構造を持つコラーゲン結合蛋白(RGD-CAP)の発現と機能Principal Investigator
- Principal Investigator
  
  能城光秀
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Molecular biological studies on regulators of endochondral bone formation
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
軟骨組織におけるRGD構造を持つコラーゲン結合蛋白の発現と機能Principal Investigator
- Principal Investigator
  
  能城光秀
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
軟骨組織における骨形成因子(BMP)の発現と機能Principal Investigator
- Principal Investigator
  
  能城光秀
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Roles of adhesion molecules and growth factors during conversion from cartilage to bone.
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
Novel factors that increase inflammation : tissue and synovial fluid levels.
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
コレステロール7α-水酸化酵素の調節機構の解明Principal Investigator
- Principal Investigator
  
  能城光秀
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Hiroshima University
歯周疾患における熱ショック蛋白質の役割に関する遺伝子レベルでの研究
- Principal Investigator
  
  森下真行
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  小児・社会系歯学
- Research Institution
  Hiroshima University

All 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004

All Journal Article Presentation Book Patent

[Book] DEC1/STRA13/SHARP2 and DEC2/SHARP1 coordinate physiological processes, including circadian rhythms in response to environmental stimuli. bHLH Factors in Development and Disease : Current topics in developmental biology2014
- Author(s)
  Kato Y, Kawamoto T, Fujimoto K, Noshiro M
- Publisher
  Elsevier(in press)
- Data Source
  KAKENHI-PROJECT-23390423
[Book] bHLH Factors in Development and Disease: Current topics in developmental biology2014
- Author(s)
  Kato Y, Kawamoto T, Fujimoto K, Noshiro M.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-23390423
[Journal Article] Different Circadian Expression of Major Matrix-Related Genes in Various Types of Cartilage : Modulation by Light-Dark Conditions2013
- Author(s)
  Honda KK, Kawamoto T, Ueda HR, Nakashima A, Ueshima T, Yamada RG, Nishimura M, Oda R, Nakamura S, Kojima T, Noshiro M, Fujimoto K, Hashimoto S, Kato Y
- Journal Title
  
  J Biochem
  
  Volume: 154(4) Issue: 4 Pages: 373-81
- DOI
  10.1093/jb/mvt068
- NAID
  40019817581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876, KAKENHI-PROJECT-25462889
[Journal Article] Identification of a new clock-related element EL-box involved in circadian regulation by BMAL1/CLOCK and HES12012
- Author(s)
  Ueshima, T., Kawamoto, T., Honda, K.K, Noshiro, M., Fujimoto, K., Nakao, S., Ichinose, N., Hashimoto, S., Gotoh, O., Kato, Y
- Journal Title
  
  Gene
  
  Volume: 510 (2) Issue: 2 Pages: 118-125
- DOI
  10.1016/j.gene.2012.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310124, KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068
[Journal Article] The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer2012
- Author(s)
  Wu, Y., Kawamoto, T., Noshiro, M., et al.(他10名)
- Journal Title
  
  Int J Oncol
  
  Volume: 41 Issue: 4 Pages: 1337-1346
- DOI
  10.3892/ijo.2012.1559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-22592232, KAKENHI-PROJECT-22791243, KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-23590386, KAKENHI-PROJECT-23592717, KAKENHI-PROJECT-23593110, KAKENHI-PROJECT-24500484, KAKENHI-PROJECT-24659876, KAKENHI-PROJECT-24791265
[Journal Article] BHLH transcription factor DEC2 regulates pro-apoptotic factor Bim in human oral cancer HSC-3 cells2012
- Author(s)
  Wu, Y., Sato, F., Kawamoto, T., Noshiro, M.
- Journal Title
  
  Biomed Res
  
  Volume: 33 Pages: 75-82
- NAID
  130004470811
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22572381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223
[Journal Article] Regulation of basic helix-loop-helix transcription factors Dec1 and Dec2 by RORα and their roles in adipogenesis.2012
- Author(s)
  Ozaki N
- Journal Title
  
  Genes to Cells
  
  Volume: 17 Issue: 2 Pages: 107-121
- DOI
  10.1111/j.1365-2443.2011.01574.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390064, KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-23659918, KAKENHI-PROJECT-24659876
[Journal Article] The basic helix-loop-helix transcription factor DEC2 inhibits TGF-beta-induced tumor progression in human pancreatic cancer BxPC-3 cells2012
- Author(s)
  Sato, F., Kawamura, H., Kawamoto, T., Noshiro, M.,(他10名)
- Journal Title
  
  Int J Mol Med
  
  Volume: 30 Issue: 3 Pages: 495-501
- DOI
  10.3892/ijmm.2012.1037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-22592232, KAKENHI-PROJECT-22791243, KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876
[Journal Article] Smad3 and Snail show circadian expression in human gingival fibroblasts, human mesenchymal stem cell, and in mouse liver2012
- Author(s)
  Sato, F., Wu, Y., Noshiro, M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419 Issue: 2 Pages: 441-446
- DOI
  10.1016/j.bbrc.2012.02.076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-22791243, KAKENHI-PROJECT-23659918
[Journal Article] BHLH transcription factor DEC2 regulates pro-apoptotic factor Bim in human oral cancer HSC-3 cells2012
- Author(s)
  Wu, Y., Sato, F., Bhawal, U.K., Kawamoto, T., Fujimoto, K., Noshiro, M., Seino, H., Morohashi, S., Kato, Y., Kijima, H
- Journal Title
  
  Biomed. Res.
  
  Volume: 33 Issue: 2 Pages: 75-82
- DOI
  10.2220/biomedres.33.75
- NAID
  130004470811
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876
[Journal Article] Roles of DEC1 and DEC2 in the core loop of the circadian clock, and clock outputs to metabolism.2011
- Author(s)
  Kato Y, Noshiro M, Fujimoto K, Kawamoto T.
- Journal Title
  
  Hirosaki Med.J.
  
  Volume: 61(Suppl.)
- Data Source
  KAKENHI-PROJECT-22590223
[Journal Article] Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells.2011
- Author(s)
  Wu, Y., Sato, F., Noshiro, M., Kato, Y., Kijima, H., et al.
- Journal Title
  
  Int J Mol Med
  
  Volume: 27 Pages: 491-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223
[Journal Article] Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells2011
- Author(s)
  Wu, Y., Sato, F., Kawamoto, T., Fujimoto, K., Noshiro, M., (他4名)
- Journal Title
  
  Int J Mol Med
  
  Volume: 27 Issue: 4 Pages: 491-495
- DOI
  10.3892/ijmm.2011.617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067, KAKENHI-PROJECT-22592068, KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-23659918, KAKENHI-PROJECT-23792139
[Journal Article] Anti-apoptotic effect of the basic helix-loop-helix(bHLH) transcription factor DEC2 in human breast cancer cells.2010
- Author(s)
  Liu, Y., Sato, F., Noshiro, M., Kato, Y., Kijima, H., et al.
- Journal Title
  
  Genes to Cells
  
  Volume: 15 Pages: 315-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223
[Journal Article] Anti-apoptotic effect of the basic helix-loop-helix (bHLH) transcription factor DEC2 in human breast cancer cells2010
- Author(s)
  Liu, Y., Sato, F., Kawamoto, T., Noshiro, M.
- Journal Title
  
  Genes Cells
  
  Volume: 15 Issue: 4 Pages: 315-325
- DOI
  10.1111/j.1365-2443.2010.01381.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590223, KAKENHI-PROJECT-22592067
[Journal Article] The liver X receptors(LXRα and LXRβ)are potent regulators for hepatic Dec1 expression.2009
- Author(s)
  Noshiro M, et al.
- Journal Title
  
  Genes to Cells 14
  
  Pages: 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209060
[Journal Article] Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression2009
- Author(s)
  Sato, F., Bhawal, U.K., Kawamoto, T., Fujimoto, K., Imaizumi, T., Imanaka, T., Kondo, J., Koyanagi, S., Noshiro, M., Yoshida, H. , et.al.
- Journal Title
  
  Genes Cells 13
  
  Pages: 131-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590226
[Journal Article] Liver X receptors (LXRalpha and LXRbeta) are potent regulators for hepatic Dec1 expression2009
- Author(s)
  Noshiro, M., Usui, E., Kawamoto, T., Sato, F., Nakashima, A., Ueshima, T., Honda, K., Fujimoto, K., Honma, S., Honma, K. , et.al.
- Journal Title
  
  Genes Cells 14
  
  Pages: 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590226
[Journal Article] DEC1 modulates the circadian phase of clock gene expression2008
- Author(s)
  Nakashima, A., Kawamoto, T., Honda, K.K., Ueshima, T., Noshiro, M., Iwata, T., Fujimoto, K., Kubo, H., Honma, S., Yorioka, N. , et.al.
- Journal Title
  
  Molecular and cellular biology 28
  
  Pages: 4080-4092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590226
[Journal Article] Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis2007
- Author(s)
  Noshiro, M., Usui, E., Kawamoto, T., Kubo, H., Fujimoto, K., Furukawa, M., Honma, S., Makishima, M., Honma, K., and Kato, Y.
- Journal Title
  
  J Biol Rhythms 22
  
  Pages: 299-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590226
[Journal Article] Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis.2007
- Author(s)
  Noshiro M, et. al.
- Journal Title
  
  J. Biol. Rhythms 22(4)
  
  Pages: 299-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209060
[Journal Article] Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis2007
- Author(s)
  Noshiro, Mら他8名
- Journal Title
  
  J. Biol. Rhythms 22
  
  Pages: 299-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590226
[Journal Article] Transcriptional repression by the basic helix-loop-helix protein Dec2 : Multiple mechanisms through E-box elements2007
- Author(s)
  Fujimoto, K., Hamaguchi, H., Hashiba, T., Nakamura, T., Kawamoto, T., Sato, F., Noshiro, M., Bhawal, U.K., Suardita, K., and Kato, Y.
- Journal Title
  
  Int J Mol Med 19
  
  Pages: 925-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590226
[Journal Article] Tissue-specific disruption of rhythmic expression of DEC1 and DEC2 in Clock mutant mice.2005
- Author(s)
  Noshiro, M., et al.
- Journal Title
  
  Journal of Biological Rhythms 20(5)
  
  Pages: 404-418
- Data Source
  KAKENHI-PROJECT-17209060
[Journal Article] Rhythmic Expression of DEC1 and DEC2 in Peripheral Tissues : DEC2 is a Potent Suppressor for Hepatic Cytochrome P450s Opposing DBP.2004
- Author(s)
  Noshiro, M., et al.
- Journal Title
  
  Genes to Cells 9(4)
  
  Pages: 317-329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390561
[Journal Article] Rhythmic Expression of DEC1 and DEC2 in Peripheral Tissues : DEC2 is a Potent Suppressor for Hep atic Cytochrome P450s Opposing DBP.2004
- Author(s)
  Noshiro, M., et al.
- Journal Title
  
  Genes to Cells 9
  
  Pages: 317-329
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390561
[Patent] 脂質代謝関連疾患の検査方法、ならびに脂質代謝関連疾患の予防および/または治療剤の評価方法2011
- Inventor(s)
  加藤幸夫、河本健、藤本勝巳、能城光秀
- Industrial Property Rights Holder
  広島大学
- Industrial Property Number
  2011-022172
- Filing Date
  2011-02-03
- Data Source
  KAKENHI-PROJECT-22590223
[Patent] 非ヒト動物、細胞、血圧調節物質の評価方法、血圧調節条件の評価方法および血圧の調節方2010
- Inventor(s)
  加藤幸夫、河本健、能城光秀、中島歩
- Industrial Property Rights Holder
  広島大学
- Industrial Property Number
  2010-236891
- Filing Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-22590223
[Patent] 非ヒト動物、細胞、血圧調節物質の評価方法、血圧調節条件の評価方法および血圧の調節方法2010
- Inventor(s)
  加藤幸夫、河本健、能城光秀、中島歩
- Industrial Property Rights Holder
  広島大学
- Industrial Property Number
  2010-236891
- Filing Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-22590223
[Patent] 軟骨・骨概日リズム遺伝子および時計モチーフ2007
- Inventor(s)
  加藤幸夫、河本健、上嶋太一、能城光秀、後藤修
- Industrial Property Rights Holder
  広島大学、(株)ツーセル
- Industrial Property Number
  2007-048189
- Filing Date
  2007-02-27
- Data Source
  KAKENHI-PROJECT-17209060
[Presentation] 時計遺伝子 DEC1 の発現調節と機能における核内受容体との関連2012
- Author(s)
  能城光秀
- Organizer
  時刻と時間の生理学
- Place of Presentation
  札幌
- Year and Date
  2012-03-10
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 概日リズムを制御する新規時計エレメント EL-box の同定2012
- Author(s)
  河本健、能城光秀、藤本勝巳、加藤幸夫
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 概日リズムを制御する新規時計エレメントEL-box の同定2012
- Author(s)
  河本健, 能城光秀, 藤本勝巳, 加藤幸夫
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  福島県郡山市
- Data Source
  KAKENHI-PROJECT-23390423
[Presentation] Transcription factors regulating differentiation of MSC2011
- Author(s)
  Takeshi Kawamoto, Hiroshi Kubo, Tomoyuki Iwata, Katsumi Fujimoto, Mitsuhide Noshiro, Yukio Kato
- Organizer
  3rd International Workshop on BioDental Education & Research Hiroshima University Graduate School of Biomedical Sciences
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23390423
[Presentation] Expression profiles of nuclear receptors and their functions in rat growth plate Chondrocytes2011
- Author(s)
  Noritsugu Ozaki, Mitsuhide Noshiro, Kiyomasa Honda, Takeshi Kawamoto, Katsumi Fujimoto, Kazuo Tanne, Yukio Kato
- Organizer
  3rd International Workshop on BioDental Education & Research Hiroshima University Graduate School of Biomedical Sciences
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23390423
[Presentation] 間葉系幹細胞の軟骨分化におけるDEC2の役割2011
- Author(s)
  笹本智子、藤本勝巳、金輪真佐美、河本健、能城光秀、道田将彦、尾崎徳継、丹根一夫、加藤幸夫
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 核内受容体 RORαによる時計遺伝子DEC1,DEC2 の発現調節と脂肪分化: 尾崎徳継2011
- Author(s)
  能城光秀、河本健、福崎麗、藤本勝巳、丹根一夫、加藤幸夫
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 核内受容体RORαによる時計遺伝子DEC1,DEC2の発現調節と脂肪分化2011
- Author(s)
  尾崎徳継、能城光秀、加藤幸夫, ら
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 間葉系幹細胞の軟骨分化におけるDEC2 の役割2011
- Author(s)
  笹本智子, 藤本勝巳, 金輪真佐美, 河本健, 能城光秀, 道田将彦, 尾崎徳継, 丹根一夫, 加藤幸夫
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23390423
[Presentation] 間葉系幹細胞の増殖・分化ならびにインテクリン発現に対する転写因子GATA6の作用2011
- Author(s)
  道田将彦、河本健、能城光秀、加藤幸夫, ら
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 核内受容体ROR α による時計遺伝子DEC1, DEC2 の発現調節と脂肪分化2011
- Author(s)
  尾崎徳継, 能城光秀, 河本健, 福崎麗, 藤本勝巳, 丹根一夫, 加藤幸夫
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23390423
[Presentation] 間葉系幹細胞の増殖・分化ならびにインテクリン発現に対する転写因子GATA6 の作用2011
- Author(s)
  道田将彦, 河本健, 能城光秀, 藤本勝巳, 金輪真佐美, 尾崎徳継, 笹本智子, 丹根一夫, 加藤幸夫
- Organizer
  第52回日本生化学会中国・四国支部例会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23390423
[Presentation] 核内受容体 (ROR・) と SREBP1c によるベーシック・ヘリックス・ループ・ヘリックス型転写因子(Dec1, Dec2) の発現調節と脂肪分化2010
- Author(s)
  尾崎徳継,能城光秀,福崎麗, 河本健,藤本勝巳,丹根一夫,加藤幸夫
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会・合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 核内受容体 (ROR・) による時計遺伝子 (Dec1, Dec2) の制御2010
- Author(s)
  尾崎徳継、能城光秀、河本健、藤本勝巳、丹根一夫、加藤幸夫
- Organizer
  第51回日本生化学会中国・四国支部例会
- Place of Presentation
  山口市
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 核内受容体(RORα)とSREBP1cによるベーシック・ヘリックス・ループ・ヘリックス型転写因子(Dec1, Dec2)の発現調節と脂肪分化2010
- Author(s)
  尾崎徳継, 能城光秀, 福崎麗, 河本健, 藤本勝巳, 丹根一夫, 加藤幸夫
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会・合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] 核内受容体(RORα)による時計遺伝子(Dec1, Dec2)の制御2010
- Author(s)
  尾崎徳継、能城光秀、河本健、藤本勝巳、丹根一夫、加藤幸夫
- Organizer
  第51回日本生化学会中国・四国支部例会
- Place of Presentation
  山口市
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-22590223
[Presentation] Novel clock-responsive elements and transcription factors involved in chondrocyte differenttiation2009
- Author(s)
  Ueshima T, Kawamoto K, Honda K, Noshiro M, Fujimoto K, Gotoh O, and Kato Y
- Organizer
  International Workshop on BioDental Education & Research
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] bHLH型転写因子DEC1は概日リズム遺伝子の位相を調節する2008
- Author(s)
  河本健、中島歩、本田清昌、上島太一、藤本勝巳、能城光秀、加藤幸夫
- Organizer
  第18回中国・四国骨代謝研究会
- Place of Presentation
  岡山市
- Year and Date
  2008-07-12
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] 明暗条件は永久軟骨の成長・代謝を制御する2008
- Author(s)
  本田清昌、河本健、中島歩、上嶋太一、藤本勝巳、西村正宏、能城光秀、加藤幸夫
- Organizer
  第21回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] ラット成長板軟骨のおける核内受容体の発現様式と機能の解析2008
- Author(s)
  尾崎徳継、能城光秀、本田清昌、林原久美子、河本健、藤本勝巳、丹根一夫、加藤幸夫
- Organizer
  第21回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] 軟骨細胞分化の概日リズムを制御する新規時間制御配列の探索と、そこに関与する転写因子の同定2008
- Author(s)
  上嶋太一、河本健、本田清昌、能城光秀、藤本勝巳、後藤修、加藤幸夫
- Organizer
  第21回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] bHLH型転写因子DECは概日リズムの位相調節に関与する2008
- Author(s)
  河本健、中島歩、本田清昌、上嶋太一、能城光秀、藤本勝巳、本間さと、加藤幸夫
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] DECは核内受容体のコリプレッサーとして機能する2008
- Author(s)
  長克武、能城光秀、加藤幸夫、河本健、藤本勝巳、槇島誠
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] The liver X receptors (LXRα and LXRβ) are potent regulators for hepatic Dec1 expression2007
- Author(s)
  能城光秀
- Organizer
  2nd World Congress of Chronobiology
- Place of Presentation
  東京
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] 軟骨細胞の分化の概日リズムを制御する数種類の新規制御配列の同定とそこに関与する転写因子の探索2007
- Author(s)
  上嶋太一、河本健、能城光秀、藤本勝巳、本田清昌、中島歩、加藤幸夫
- Organizer
  第25回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] 哺乳類の生物時計と環境適応2007
- Author(s)
  能城光秀
- Organizer
  広島県環境計量証明事業協会研究会
- Place of Presentation
  広島市
- Year and Date
  2007-04-23
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] The liver X receptors (LXRα and LXRβ) are potent regulators for hepatic Dec1 expression2007
- Author(s)
  Noshiro M., et. al.
- Organizer
  2nd World Congress of Chronobiology
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-17209060
[Presentation] 軟骨細胞分化の概日リズムを制御する新規配列の探索とそこに関与する転写因子の同定2007
- Author(s)
  上嶋太一、河本健、本田清昌、能城光秀、藤本勝巳、後藤修、加藤幸夫
- Organizer
  中四国骨代謝研究会
- Place of Presentation
  岡山市
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] DEC1 modulates circadian phase of clock gene expression2007
- Author(s)
  Nakashima A., Kawamoto T., Honda K., Ueshima T., Noshiro M., Fujimoto K.,Kubo H., Kato Y.
- Organizer
  2^<nd> World Congress of Chronobiology
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] The liver X receptors (LXRa and LXRb) are potent regulators for hepatic Dec1 expression2007
- Author(s)
  Noshiro M., Usui E., Kawamoto T., Sato F., Nakashima A., Furukawa M., Ueshima T., Honda K., Fujimoto K., Honma S., Honma K., Kato Y.
- Organizer
  2^<nd> World Congress of Chronobiology
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] DEC1による概日リズム調節の機構2007
- Author(s)
  河本健、本田清昌、藤本勝巳、能城光秀、加藤幸夫
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-19590226
[Presentation] The liver X receptors (LXRa and LXRb) are potent regulators for hepatic Dec1 expression2007
- Author(s)
  Noshiro, M.
- Organizer
  2^<nd> World Congress of Chronobiology
- Place of Presentation
  Tokyo
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19590226

1. KATO Yukio (10112062)

# of Collaborated Projects: 9 results

# of Collaborated Products: 9 results
2. KAWAMOTO Takeshi (50224861)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
3. FUJIMOTO Katsumi (40294566)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. OKADA Yasunori (00115221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHEN Ming (20294572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HAYAKAWA Taro (80064822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 森下真行 (90166405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 林幸三 (50180964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 川嶋芳枝 (80253087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAN Weiqun (80274091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中舛和子 (00311811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 来田吉弘 (10304429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. LEE Kaechoon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. V.SEGRE Gino

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 後藤修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 市瀬夏洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NOSHIRO Mitsuhide 能城 光秀

能代 光秀 ノシロ ミツヒデ

能城 光秀 ノシロ ミツヒデ

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Study on the roles of DEC1 and DEC2 in the rhythmic regulation of lipid metabolism.Principal Investigator

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Regulatory mechanism of rhythmic expression of cholesterol metabolizing enzymes by clock-related gene DEC1 and DEC2Principal Investigator

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Study on the effects of statin on growth and differentiation of cartilagePrincipal Investigator

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Regulation and function of retinol binding protein in cartilagePrincipal Investigator

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Expression and function of RGD-CAP conatining RGD-motif in cartilagePrincipal Investigator

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軟骨組織におけるRGD構造を持つコラーゲン結合蛋白(RGD-CAP)の発現と機能Principal Investigator

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軟骨組織におけるRGD構造を持つコラーゲン結合蛋白の発現と機能Principal Investigator

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NOSHIRO Mitsuhide 能城光秀

能代光秀ノシロミツヒデ

能城光秀ノシロミツヒデ