SHIBASAKI TAmotsu 芝崎保

Researcher Number	00147399
Other IDs
Affiliation *help	2010 – 2012 : Nippon Medical School, 医学(系)研究科(研究院), 教授 2012 : 日本医科大学, 大学院・医学研究科, 教授 2007 – 2010 : Nippon Medical School, Graduate School of Medicine, Professor 2004 – 2009 : 日本医大, 医学(系)研究科(研究院), 教授 2006 : 日本医科大学, 大学院医学研究科, 教授 … More
Research Field	Principal Investigator 内分泌・代謝学 Except Principal Investigator Endocrinology / Endocrinology / Circulatory organs internal medicine / 内分泌・代謝学
Keywords	Principal Investigator 成長ホルモン放出因子 / 視床下部 / 成長ホルモン / ソマトスタチン / ノルアドレナリン / 摂食行動 / 神経性食欲不振症 / Insulin tolerance test / Growth hormone / ACTH放出ホルモン … More Except Principal Investigator ノルアドレナリン / グレリン / ストレス / グレリン受容体 / noradrenaline / corticotropin releasing factor / corticotropin-releasing factor / 褐色脂肪組織 / エネルギー代謝 / ghrelin receptor / 視床下部 / 体脂肪 / stress / brown adipose tissue / 視床下部室傍核 / ghrelin / 条件恐怖ストレス / 褐色脂肪細胞 / 成長ホルモン分泌惹起物質 / 追いつき成長 / マイクロDNA / microdialysis / DNA メチル化 / 低出生体重 / ウロコルチン / hypertension / アミロライド感受性ナトリウムチャネル / 弓状核 / pseudohypoaldosteronism / トランスジェニックラット / arcuate nucleus / growth hormone secretagogue / テイルピンチ / transgenic rat / 中枢神経核 / oncogene / 成長ホルモン分泌 / Vasoactive Substance / paraventricular nucleus of the hypothalamus / エネルギー代謝調節 / 迷走神経 / polymorphysim / 迷走神経節 / マイクロ RNA / 覚醒 / マイクロダイアリシス / アトピー性皮膚炎 / urocortin / 低栄養 / 摂食行動 / tail pinch / 偽性低アルドステロン症 / 遺伝子多型 / Nucleus of Central Nervesystem / uncoupling protein / ストレス反応 / UCP1 / conditioned fear / food intake / amiloride-sensitive sodium channel / 母胎低栄養 / オンコジーン / マイクロRNA / CRF受容体拮抗薬 / DNAメチル化 / paraventricular nucleus / 脂肪代謝 / エクソソーム / vagal nerve / 血管作動性物質 / Hypertension / 高血圧症 / CRF受容体 / 高血圧 / 遺伝子解析 / 成長ホルモン受容体 Less

The analysis of epigenetic changes in GH-IGF-1 axis of small for gestational age ratsPrincipal Investigator
- Principal Investigator
  
  SHIBASAKI Tamotsu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
Study on energy storage mechanism of ghrelin using transgenic rats whose ghrelin receptor is suppressedPrincipal Investigator
- Principal Investigator
  
  SHIBASAKI TAmotsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
Study on the role of ghrelin in the regulatory mechanism of adiposity using transgenic rats whose ghrelin receptor expression is attenuatedPrincipal Investigator
- Principal Investigator
  
  SHIBASAKI Tamotsu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
Study on the function s of growth hormone secretagogue receptorPrincipal Investigator
- Principal Investigator
  
  SHIBASAKI Tamotsu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
アトピー性皮膚炎のストレスによる増悪機序の神経内分泌学および免疫学的解析
- Principal Investigator
  
  鈴木かやの, 金子勝美
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
Study on the mechanism of stress response in the central nervous system.Principal Investigator
- Principal Investigator
  
  SHIBASAK Tamotsu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
The role of the amiloride-sensitive sodium channel in hypertension.
- Principal Investigator
  
  ARAI Keiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nippon Medical School
Role of vasoactive substances and oncogenes in central nerve system unclei on stress-inducedhypertensiverat
- Principal Investigator
  
  DEMURA Hiroshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tokyo Women's Medical College
神経性食欲不振症の病因、病態に関する神経内分泌学的および分子生物学的検討Principal Investigator
- Principal Investigator
  
  芝崎保
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tokyo Women's Medical University
Basic and Clinical Studies of Regulatory Mechanism of GH SecretionPrincipal Investigator
- Principal Investigator
  
  SHIBASAKI Tamotsu
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tokyo Women's Medical College
成長ホルモン放出因子のGH分泌調節機構における役割と中枢作用に関する研究Principal Investigator
- Principal Investigator
  
  芝崎保
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tokyo Women's Medical University

All 2013 2012 2010 2009 2008 2007 2006 2005 2004 2002

All Journal Article Presentation

[Journal Article] Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats.2010
- Author(s)
  Mano-Otagiri A, Iwasaki-Sekino A, Nemoto T, Ohata H, Shibasaki T.
- Journal Title
  
  Regulat Pept 160
  
  Pages : 81-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591103
[Journal Article] Ghrelin suppreses noradrenaline release in the brown adipose tissue of rats.2009
- Author(s)
  Mano-Otagiri A, Ohata H, Iwasaki-Sekino A, Shibasaki T.
- Journal Title
  
  J Endocrinol 201
  
  Pages : 341-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591103
[Journal Article] Growth hormone-releasing hornlone(GHRH)neurons in the arcuate nucleus(Arc)of the hypothalamus are decreased in the transgenic rats whose expression of ghrelin receptor is attenuated:evidence that ghrelin receptor is involved in the up-regulation of GHRH expression in the Arc2006
- Author(s)
  Mano-Otagiri A, Shibasaki T, et. al.
- Journal Title
  
  Endocrinology 14
  
  Pages : 4093-4103
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590969
[Journal Article] Plasma levels of intact and degraded ghrelin and their responses to glucose infusion in anorexia nervosa2004
- Author(s)
  Hotta M, Ohwada R, Kakakami H, Shibasaki T, Hizuka N, Takano K.
- Journal Title
  
  J Clin Endocrinol Metab 89(11)
  
  Pages : 5707-5712
- Data Source
  KAKENHI-PROJECT-14571077
[Journal Article] Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity.2002
- Author(s)
  Shuto Y, Shibasaki T, et al.
- Journal Title
  
  J Clin Invest 109
  
  Pages : 1429-1436
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571077
[Journal Article] Hypothalamic growth hormone secretagogue Receptor regulates growth hormone secretion, feeding, and adiposity.2002
- Author(s)
  Shuto Y, Shibasaki T, et al.
- Journal Title
  
  J Clin Invest 109(11)
  
  Pages : 1429-1436
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571077
[Presentation] 低出生体重ラット仔でみられる内分泌学的異常2013
- Author(s)
  根本崇宏、芝崎保
- Organizer
  第86回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-23659480
[Presentation] 離乳時までに追いつき成長を示さなかった妊娠中のカロリー制限母ラットからの出生仔における成長ホルモン受容体発現低下の機序2012
- Author(s)
  根本崇宏,芝崎保
- Organizer
  第85回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-23659480
[Presentation] グレリンの褐色脂肪組織におけるノルアドレナリン分泌抑制作用への加齢の影響2008
- Author(s)
  眞野あすか, 岩崎あずさ, 芝崎保
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森市
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-20591103
[Presentation] グレリンのエネルギー代謝調節機構における役割の解析2007
- Author(s)
  眞野あすか、芝崎保, ら
- Organizer
  第80回日本内分泌学会学術総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590969
[Presentation] グレリンのエネルギー代謝調節機構における役割の解析2007
- Author(s)
  眞野あすか、芝崎保, ら
- Organizer
  第80回日本内分泌学会学術総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-17590969
[Presentation] Roles of ghrelin in the regulatory mechanism of energy metabolism2006
- Author(s)
  Mano A, Ohata H, Iwasaki A, Nemoto T, Shuto Y, Sugihara H, Oikawa S, Shibasaki T
- Organizer
  79th Japan Endocrine
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590969
[Presentation] Actions of ghrelin/growth hormone Secretagogue (GHS) on brown adipose tissue2005
- Author(s)
  Mano A, Sekino A, Nemoto T, Inada S, Shuto Y, Sugihara H, Oikawa S, Shibasaki T
- Organizer
  78th Japan Endocrine Society Meeting
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590969

1. OHATA Hisayuki (80256924)

# of Collaborated Projects : 4results

# of Collaborated Products : 2results
2. ARAI Keiko (60277118)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
3. NEMOTO Takahiro (40366654)

# of Collaborated Projects : 3results

# of Collaborated Products : 5results
4. MANO Asuka (50343588)

# of Collaborated Projects : 2results

# of Collaborated Products : 8results
5. 鈴木かやの (90322510)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. DEMURA Hiroshi (90075226)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. NARUSE Mitsuhide (40120018)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 金子勝美 (50267150)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

SHIBASAKI TAmotsu 芝崎 保

Research Projects

Research Products

Co-Researchers

The analysis of epigenetic changes in GH-IGF-1 axis of small for gestational age ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on energy storage mechanism of ghrelin using transgenic rats whose ghrelin receptor is suppressedPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the role of ghrelin in the regulatory mechanism of adiposity using transgenic rats whose ghrelin receptor expression is attenuatedPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the function s of growth hormone secretagogue receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アトピー性皮膚炎のストレスによる増悪機序の神経内分泌学および免疫学的解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism of stress response in the central nervous system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of the amiloride-sensitive sodium channel in hypertension.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of vasoactive substances and oncogenes in central nerve system unclei on stress-inducedhypertensiverat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経性食欲不振症の病因、病態に関する神経内分泌学的および分子生物学的検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic and Clinical Studies of Regulatory Mechanism of GH SecretionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

成長ホルモン放出因子のGH分泌調節機構における役割と中枢作用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats.2010

Author(s)

Journal Title

Data Source

[Journal Article] Ghrelin suppreses noradrenaline release in the brown adipose tissue of rats.2009

Author(s)

Journal Title

Data Source

[Journal Article] Growth hormone-releasing hornlone(GHRH)neurons in the arcuate nucleus(Arc)of the hypothalamus are decreased in the transgenic rats whose expression of ghrelin receptor is attenuated:evidence that ghrelin receptor is involved in the up-regulation of GHRH expression in the Arc2006

Author(s)

SHIBASAKI TAmotsu 芝崎保