Nishiyama Makoto 西山真

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NISHIYAMA Makoto 西山真

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Researcher Number	00208240
Other IDs	https://orcid.org/0000-0001-8143-8052
Affiliation (Current)	2023: 東京大学, 大学院農学生命科学研究科(農学部), 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京大学, 大学院農学生命科学研究科(農学部), 教授 2009 – 2020: The University of Tokyo, 生物生産工学研究センター, 教授 2004 – 2006: 東京大学, 生物生産工学研究センター, 教授 1994 – 2002: 東京大学, 生物生産工学研究センター, 助教授 1989 – 1993: 東京大学, 農学部, 助手
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Applied microbiology / Medium-sized Section 38:Agricultural chemistry and related fields Except Principal Investigator 応用微生物学・応用生物化学 / 応用微生物学・発酵学 / Applied microbiology / Applied biochemistry / Bioproduction chemistry/Bioorganic chemistry / Biophysics / 発酵・醸造
Keywords	Principal Investigator 電子伝達 / Thermus thermophilus / キャリアタンパク質 / リジン生合成 / 構造生物学 / 蛋白質工学 / 亜硝酸還元酵素 / 微生物 / 進化 / 放線菌 … More / 結晶構造解析 / 生合成 / アルギニン生合成 / 耐熱性酵素 / アミノ基キャリアタンパク質 / アミノ酸 / substrate specificity / 基質特異性 / リジン生合成経路 / 酵素 / 二次代謝産物生合成 / アスパラギン酸キナーゼ / フィードバック阻害 / X線結晶構造解析 / フォールディング / リンゴ酸脱水素酵素 / 部位特異的変異 / 反応機構 / クエン酸回路 / ロイシン / アルギニン / リジン / 分子進化 / マレイマイシン / 構造解析 / 二次代謝産物 / 生物活性物質 / 二次代謝 / transcriptional regulation / molecular evolution / X-ray crystallographic analysis / lyine biosynthesis / Thermus species / 気質特異性 / 転写調節 / 分子進化工学 / Thermus属細菌 / evolution / arginine biosynthesis / α-aminoadipate / lysine biosynthesis / アルギニン生合成経路 / トリカルボン酸回路 / αアミノアジピン酸 / αaminoadipate pathway / aspartate kinase / lysine biosynthetic pathway / タンパク質工学 / αアミノアジピン酸経路 / heme-containing protein / copper protein / nitirc oxide reductase / electron transfer / nitrite reductase / ヘムタンパク質 / 銅タンパク質 / 一酸化窒素還元酵素 / 遺伝子 / 発現制御 / 応用微生物 / バイオテクノロジー / 結晶構造 / 古細菌 / 好熱性細菌 / アミノ酸生合成 / 好熱菌 / 天然物化学 / 二次代謝生合成 / ホモクエン酸合成酵素 / 機能分化 / 超好熱性古細菌 / ロイシン生合成 / 微生物酵素 / シュードアズリン / リンゴ酸脱水素酵素酵素 / 蛋白質相互作用 / 蛋白質リフォールディング / 蛋白質間相互作用 / 銅蛋白質 / 銅蛋白 / 脱窒 / 蛋白工学 … More Except Principal Investigator 抗生物質生産 / 放線菌 / 形質転換植物 / Phytoremediation / Bioaugmentation / Bioremediation / NMR / シグナル伝達 / Signal transduction / A-factor / 形態分化 / 蛋白工学 / 抗生物質 / Thermus thermophilus / 短鎖アシル化 / タンパク質翻訳後修飾 / タンパク質相互作用 / タンパク質間相互作用 / 代謝調節 / CoA体代謝 / アミノ酸代謝 / タンパク質アセチル化酵素 / タンパク質アシル化修飾 / diterpene cyclase / phytoalexin / transcription factor / 12-oxophytodienoic acid reductase / jasmonic acid-responsive gene / signal transduction / defense response gene / suspension-cultured rice cell / ジテルペン環化酵素遺伝子 / 植物ホルモン / ジテルペン炭化水素環化酵素遺伝子 / 病害抵抗性 / ジテルペン環化酵素 / フィトアレキシン / 転写因子 / 12-オキソフィトジエン酸還元酵素 / ジャスモン酸応答性遺伝子 / 防御応答遺伝子 / イネ培養細胞 / Transgenic Plants / Monitoring / Gene transfer / Dioxin / Phytoremedhiation / モニタリング / 遺伝子転移 / ダイオキシン / nuclear magnetic resonance / motor protein / smooth muscle / myosin / モータータンパク質 / 核磁気共鳴 / モーター蛋白質 / 平滑筋 / ミオシン / Mucor pusillus / Host-vector system / Protein engineering / Mucor rennin / Milk-clotting enzyme / ムコールペプシン / Rhigomucor pusillus / 部位特異的変異法 / 蛋白質工学 / ムコールプシルス / 宿主-ベクター系 / ムコールレンニン / 凝乳酵素 / Morphogenesis / Antibiotic / Utoregulator / Streptomycetes / A-ファクター / 自己調節因子 / Protein phosphorylation / morphogenesis / Antibiotic production / Streptomyces / 蛋白質のリン酸化 / 情報伝達機構 / リフォ-ルデイング / リフォ-ルディング / 反応遷移状態 / サブサイト / 部位特異的変異 / ムコ-ルレンニン / キモシン / アスパラギン酸プロテア-ゼ / afsR遺伝子 / 放線菌の二次代謝 / レセプタ-蛋白 / A-ファクタ- / <afsR>___ー遺伝子 / 蛋白リン酸化 / 胞子形成 / Aーファクタ- Less

Studies on mining of novel enzymes functioning in secondary metabolite biosynthesis in Streptomyces and their molecular mechanism.Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
Studies on mechanisms of biosynthesis of biomolecules via amino-group carrier protein and expansion of structural diversity of secondary metabolitesPrincipal Investigator
- Principal Investigator
  
  Nishiyama Makoto
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Elucidation of structures and functions of metabolic enzymes of lysine and related compounds and their molecular evolutionPrincipal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Metabolic regulation via protein acylation in Thermus thermophilus
- Principal Investigator
  
  Yoshida Ayako
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
  Applied microbiology
- Research Institution
  The University of Tokyo
Elucidation of mechanisms of biomaterial conversion mediated by amino group-modifying carrier protein and applicationPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA MAKOTO
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
リジン生合成および関連一次代謝系酵素群の機能および分子進化の解析Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Structural biology for elucidation of lysine biosynthesis and its regulatory mechanismsPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Structure-function relationship of novel lysine biosynthetic enzymes and analysis of molecular evolution of the pathwayPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Makoto
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Analysis of novel lysine biosynthesis in Thermus and its regulationPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Makoto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  THE UNIVERSITY OF TOKYO
Studies on signal transduction pathways of jasmonic acid in suspension-cultured rice cells
- Principal Investigator
  
  YAMANE Hisakazu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  THE UNIVERSITY OF TOKYO
Analysis of mechanisms of regulation of aspartate kinase and lysine biosyntheseis in Thermus thermophilusPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Makoto
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  THE UNIVERSITY OF TOKYO
Bioremediation of xenobiotic compounds including dioxins
- Principal Investigator
  
  OMORI Toshio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  THE UNIVERSITY OF TOKYO
耐熱性リンゴ酸脱水素酵素のドメインの折れたたみ機構に関する研究Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Analysis of structure-function relationships on smooth muscle myosin using NMR and X-ray crystallography.
- Principal Investigator
  
  TANOKURA Masaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biophysics
- Research Institution
  University of Tokyo
Studies on electron-transferring mechanism in an nitrite-reducing system containing Cu-proteinsPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Makoto
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
ドメインに分断されたリンゴ酸脱水素酵素を用いた折れたたみ機構に関する研究Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
精密な立体構造に基づく2つの銅蛋白質の相互作用様式の解析Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
耐熱性リンゴ酸脱水素酵素の安定性及び折れたたみ機構に関する研究Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
蛋白工学的手法による亜硝酸還元系を構成する銅蛋白間の相互作用様式の解析Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
銅蛋白間の電子伝達機構に関する蛋白工学的研究Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
Regulation of secondary metabolism and cell differentiation by A-factor and protein phosphorylation in Streptomyces.
- Principal Investigator
  
  HORINOUCHI Sueharu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
Improvement of milk-clotting enzyme, Mucor rennin, by protein engineering and 「genetic engineering.
- Principal Investigator
  
  HORINOUCHI Sueharu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
蛋白工学を用いた銅蛋白間の電子伝達機構の解析Principal Investigator
- Principal Investigator
  
  西山真
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
Regulation of secondary metabolism and cellular differentiation by A-factor and signal transduction systems in Streptomyces
- Principal Investigator
  
  HORINOUCHI Sueharu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  The University of Tokyo
ウシキモシンおよびムコ-ルレンニンの蛋白工学的研究
- Principal Investigator
  
  別府輝彦
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  The University of Tokyo
放線菌の化学調節物質Aーファクタ-をめぐる調節ネットワ-クに関する研究
- Principal Investigator
  
  HORINOUCHI Sueharu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  発酵・醸造
- Research Institution
  The University of Tokyo

[Book] アミノ基結合型キャリアタンパク質を介した二次代謝生合成機構の解明と新規有用生物活性物質の探索2016
- Author(s)
  長谷部文人、西山　真
- Total Pages
  6
- Publisher
  日本応用酵素協会
- Data Source
  KAKENHI-PROJECT-24228001
[Book] バイオサイエンスとインダストリー「リジン生合成の新機構:タンパク質によるアミノ基修飾」2010
- Author(s)
  西山真
- Total Pages
  79
- Publisher
  (財)バイオインダストリー協会
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Reconstitution of a Highly Reducing Type II PKS System Reveals 6π-Electrocyclization Is Required for o-Dialkylbenzene Biosynthesis2021
- Author(s)
  Zhang J, Yuzawa S, Thong WL, Shinada T, Nishiyama M, Kuzuyama T.
- Journal Title
  
  J Am Chem Soc
  
  Volume: 143 Issue: 7 Pages: 2962-2969
- DOI
  10.1021/jacs.0c13378
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06453, KAKENHI-PUBLICLY-19H04661, KAKENHI-PROJECT-17H06168
[Journal Article] Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius2021
- Author(s)
  Suzuki, T., Tomita, T., Hirayama, K., Suzuki, M., Kuzuyama, T., and Nishiyama M.
- Journal Title
  
  FEBS Journal
  
  Volume: 288 Issue: 6 Pages: 1975-1988
- DOI
  10.1111/febs.15527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] Guanidyl modification of the 1-azabicyclo[3.1.0]hexane ring in ficellomycin essential for its biological activity2020
- Author(s)
  Kurosawa, S., Matsuda, K., Hasebe, F., Shiraishi, T., Shin-ya, K., Kuzuyama, T., and Nishiyama, M.
- Journal Title
  
  Organic and Biomolecular Chemistry
  
  Volume: 15 Issue: 27 Pages: 5137-5144
- DOI
  10.1039/d0ob00339e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria2020
- Author(s)
  Kei Sakaki, Keita Ohishi, Tetsu Shimizu, Ikki Kobayashi, Naoki Mori, Kenichi Matsuda, Takeo Tomita, Hidenori Watanabe, Kan Tanaka, Tomohisa Kuzuyama and Makoto Nishiyama
- Journal Title
  
  Nature Chem. Biol.
  
  Volume: 16 Issue: 4 Pages: 415-422
- DOI
  10.1038/s41589-019-0461-9
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04720, KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-18H02124
[Journal Article] Genome-mining of amino group carrier protein-mediated machinery led to the discovery of an unprecedented hydrazine-forming enzyme in bacteria.2020
- Author(s)
  松田研一，西山真
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 130-135
- DOI
  10.14952/SEIKAGAKU.2020.920130
- NAID
  40022176215
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] Biochemical characterization of archaeal homocitrate synthase from Sulfolobus acidocaldarius2019
- Author(s)
  Suzuki, T., Akiyama, N., Ayako, Y., Tomita, T., Lassak, K., Haurat, M. F., Okada, T., Takahashi, K., Albers, S.-V., Kuzuyama, T., and Nishiyama, M.
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 1 Pages: 126-134
- DOI
  10.1002/1873-3468.13550
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-17J40083
[Journal Article] An ornithine ω-aminotransferase required for growth in the absence of exogenous proline in the archaeon Thermococcus kodakarensis2018
- Author(s)
  Zheng Ren-Chao、Hachisuka Shin-ichi、Tomita Hiroya、Imanaka Tadayuki、Zheng Yu-Guo、Nishiyama Makoto、Atomi Haruyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 10 Pages: 3625-3636
- DOI
  10.1074/jbc.ra117.001222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria2018
- Author(s)
  Matsuda Kenichi、Tomita Takeo、Shin-ya Kazuo、Wakimoto Toshiyuki、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 29 Pages: 9083-9086
- DOI
  10.1021/jacs.8b05354
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06448, KAKENHI-PLANNED-16H06453, KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-18H02581, KAKENHI-PROJECT-17F17114
[Journal Article] Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW2017
- Author(s)
  S. Fujita, F. Hasebe, S.-H. Cho, T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 491 Issue: 2 Pages: 409-415
- DOI
  10.1016/j.bbrc.2017.07.088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168, KAKENHI-PROJECT-17J40083
[Journal Article] Genome mining of amino group carrier protein-mediated machinery: discovery and biosynthetic characterization of a natural product with unique hydrazone unit2017
- Author(s)
  K. Matsuda, F. Hasebe, Y. Shiwa, Y. Kanesaki, T. Tomita, H. Yoshikawa, K. Shin-ya, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 12 Issue: 1 Pages: 124-131
- DOI
  10.1021/acschembio.6b00818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06168
[Journal Article] Nobel stand-alone RAM-domain mediated catalytic control of anthranilate phosphoribosyltransferase in tryptophan biosynthesis in Thermus thermophilus2017
- Author(s)
  T. Kubota, H. Matsushita, T. Tomita, S. Kosono, M. Yoshida, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  Extremophiles
  
  Volume: 1 Issue: 1 Pages: 73-83
- DOI
  10.1042/bcj20160699
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07382, KAKENHI-PROJECT-17H06168
[Journal Article] Characterization of two β-decarboxylating dehydrogenases from Sulfolobus acidocaldarius2016
- Author(s)
  Takahashi Kento、Nakanishi Fumika、Tomita Takeo、Akiyama Nagisa、Lassak Kerstin、Albers Sonja-Verena、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Extremophiles
  
  Volume: 20 Issue: 6 Pages: 843-853
- DOI
  10.1007/s00792-016-0872-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Crystal structure of the LysY・LysW complex from Thermus thermophilus2016
- Author(s)
  Tetsu Shimizu, Takeo Tomita, Tomohisa Kuzuyama, and Makoto Nishiyama
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 19 Pages: 9948-9959
- DOI
  10.1074/jbc.m115.707034
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Altered acetylation and succinylation profiles in Corynebacterium glutamicum in response to conditions inducing glutamate overproduction.2016
- Author(s)
  Mizuno Y., Nagano-Shoji M., Kubo S., Kawamura Y., Yoshida A., Kawasaki H., Nishiyama M., Yoshida M. and Kosono S.
- Journal Title
  
  MicrobiologyOpen
  
  Volume: 5 Issue: 1 Pages: 152-173
- DOI
  10.1002/mbo3.320
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14685, KAKENHI-PROJECT-26870113, KAKENHI-PROJECT-26221204
[Journal Article] Amino group carrier protein-mediated secondary metabolite biosynthesis in Streptomyces.2016
- Author(s)
  Hasebe, F., Matsuda, K., Shiraishi, T., Futamura, Y., Nakano, T., Tomita, T., Ishigami, K., Taka, H., Mineki, R., Fujimura, T., Osada, H., Kuzuyama, T., Nishiyama, M.
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 12 Issue: 11 Pages: 967-972
- DOI
  10.1038/nchembio.2181
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14714, KAKENHI-PROJECT-16K01834, KAKENHI-PROJECT-24228001
[Journal Article] Lysine Biosynthesis ofThermococcus kodakarensiswith the Capacity to Function as an Ornithine Biosynthetic System2016
- Author(s)
  Yoshida Ayako、Tomita Takeo、Atomi Haruyuki、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 41 Pages: 21630-21643
- DOI
  10.1074/jbc.m116.743021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Determinants of dual substrate specificity revealed by the crystal structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate・Mg2+・NADH2016
- Author(s)
  Takahashi Kento、Tomita Takeo、Kuzuyama Tomohisa、Nishiyama Makoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 478 Issue: 4 Pages: 1688-1693
- DOI
  10.1016/j.bbrc.2016.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ•LysW complex from Thermus thermophilus2015
- Author(s)
  Ayako Yoshida, Takeo Tomita, Tsutomu Fujimura, Chiharu Nishiyama, Tomohisa Kuzuyama, and Makoto Nishiyama
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 290 Issue: 1 Pages: 435-447
- DOI
  10.1074/jbc.m114.595983
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24228001, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26870113
[Journal Article] Changes in the acetylome and succinylome of Bacillus subtilis in response to carbon source.2015
- Author(s)
  Kosono S., Tamura M., Suzuki S., Kawamura Y., Yoshida A., Nishiyama M., Yoshida M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0131169-e0131169
- DOI
  10.1371/journal.pone.0131169
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14685, KAKENHI-PROJECT-26870113
[Journal Article] Genome-wide comprehensive analysis of transcriptional regulation by ArgR in Thermus thermophilus2014
- Author(s)
  Naoki Iwanaga, Kaori Ide, Takeshi Nagashima, Takeo Tomita, Yoshihiro Agari, Akeo Shinkai, Seiki Kuramitsu, Mariko Okada-Hatakeyema, Tomohisa Kuzuyama, and Makoto Nishiyama
- Journal Title
  
  Extremophiles
  
  Volume: 18 Issue: 6 Pages: 995-1008
- DOI
  10.1007/s00792-014-0669-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Two ATP-binding cassette transporters involved in (S)-2-aminoethyl-cysteine uptake in Thermus thermophilus2013
- Author(s)
  Y. Kanemaru, F. Hasebe, T. Tomita, T. Kuzuyama, M. Nishiyama
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 195 Issue: 17 Pages: 3845-3853
- DOI
  10.1128/jb.00202-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24228001
[Journal Article] Evolution of lysine biosynthesis in the phylum Deinococcus-Thermus2012
- Author(s)
  H.Nishida, M.Nishiyama
- Journal Title
  
  International Journal of Evolutionary Biology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Convergent strategies in biosynthesis2011
- Author(s)
  T. Dairi, T. Kuzuyama, M. Nishiyama, and I. Fujii
- Journal Title
  
  Nat Prod Rep
  
  Volume: 28 Pages: 1054-1086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase2011
- Author(s)
  T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 37841-37848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Hetero-oligomeric glutamate dehydrogenase from Thermus thermophilus2010
- Author(s)
  T. Tomita, T. Miyazaki. J. Miyazaki, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Microbiology
  
  Volume: 156 Pages: 3801-3813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Enhancement of latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution2010
- Author(s)
  Y. Suzuki, K. Asada, J. Miyazaki, T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Biochem J
  
  Volume: 431 Pages: 401-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus2010
- Author(s)
  T. Okada, T. Tomita, A. P. Wulandari, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 4195-4205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Mechanism of concerted inhibition ofα_2β_2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum2010
- Author(s)
  A. Yoshida, T. Tomita, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 27477-27486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates inα-aminoadipate aminotransferase from Thermus thermophilus2009
- Author(s)
  T. Ouchi, T. Tomita, T. Miyagawa, Kuzuyama, and M. Nishiyama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 388 Pages: 2127-2127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus2009
- Author(s)
  A. Horie, T. Tomita, A. Saiki, H. Kono, H. Taka, R. Mineki, T. Fujimura, C. Nishiyama, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Nat Chem Biol
  
  Volume: 5 Pages: 673-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Mechanism for multiple-substrates recognition ofα-aminoadipate aminotransferase from Thermus thermophilus2009
- Author(s)
  T. Tomita, T. Miyagawa, T. Miyazaki, S. Fushinobu, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  Proteins
  
  Volume: 75 Pages: 348-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus2009
- Author(s)
  A. Yoshida, T. Tomita, H. Kono, S. Fushinobu, T. Kuzuyama, and M. Nishiyama
- Journal Title
  
  FEBS J
  
  Volume: 276 Pages: 3124-3136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380057
[Journal Article] Kinetics and product analysis of the reaction catalyzed by recombinant homoaconitase from Thermus thermophilus.2006
- Author(s)
  Y.Jia, T.Tomita, K.Yamauchi, M.Nishiyama, D.R.J.Palmer.
- Journal Title
  
  Biochemical Journal 396
  
  Pages: 479-485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380056
[Journal Article] Involvement of arginine repressor in lysine biosynthesis of Thermus thermophilus2006
- Author(s)
  K.Fujiwara, T.Tsubouchi, T.Kuzuyama, M.Nishiyama.
- Journal Title
  
  Microbiology 152
  
  Pages: 3585-3594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380056
[Journal Article] Leader peptide-mediated transcriptional attenuation of lysine biosynthetic gene cluster in Thermus thermophilus2005
- Author(s)
  T.Tsubouchi, R.Mineki, H.Taka, N.Kaga, K.Murayama, C.Nishiyama, H.Yamane, T.Kuzuyama, M.Nishiyama.
- Journal Title
  
  Journal of Biological Chemistry 280
  
  Pages: 18511-18516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380056
[Journal Article] Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus : involvement of hydrophobic dimer-dimer interaction in extremely high thermotolerance2005
- Author(s)
  J.Miyazaki, S.Fushinobu, K.Asada, T.Kuzuyama, M.Nishiyama.
- Journal Title
  
  Journal of Bacteriology 187
  
  Pages: 6779-6788
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380056
[Journal Article] α-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus2004
- Author(s)
  T.Miyazaki, J.Miyazaki, H.Yamane, M.Nishiyama.
- Journal Title
  
  Microbiology 150
  
  Pages: 2327-2334
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380056
[Journal Article] Functional analysis of the small subunit of the putative homoaconitase from Pyrococcus horikoshii in the Thermus lysine pathway2004
- Author(s)
  T.Lombo, N.Takaya, J.Miyazaki, K.Gotoh, M.Nishiyama, T.Kosuge, A.Nakamura, T.Hoshino.
- Journal Title
  
  FEMS Microbiological Letters. 233
  
  Pages: 315-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380056
[Journal Article] Molecular cloning and characterization of a cDNA encoding ent-cassa-12,15-diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from suspension-cultured rice cells treated with a chitin elicitor.2004
- Author(s)
  E.-M.Cho, A.Okada, H.Kenmoku, T.Toyomasu, T.Sassa, A.Yajimal, G.Yabutai, K.Mori, H.Oikawa, H.Toshima, N.Shibuya, T.Omori, M.Nishiyama, H.Yamane
- Journal Title
  
  The Plant Journal 37
  
  Pages: 1-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12460051
[Journal Article] Cloning and characterization of a jasmonic acid-responsive gene encoding 12-oxophytodienoic acid reductase in suspension-cultured rice cells.2003
- Author(s)
  H.Sobajima, M.Takeda, M.Sugimori, N.Kobashi, K.Kiribuchi, E.-U.Cho, C.Akimoto, T.Yamaguchi, E.Minami, N.Shibuya, F.Schaller, E.W.Weiler, T.Yoshihara, H.Nishida, H.Nojiri, T, Omori, M.Nishiyama, H.Yamane
- Journal Title
  
  Planta 216
  
  Pages: 692-698
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12460051
[Journal Article] Cloning and characterization of cDNAs for the jasmonic acid-responsive genes RRJ1 and RRJ2 in suspension-cultured rice cells.2002
- Author(s)
  M.Sugimori, K.Kiribuchi, C.Akimoto, T.Yamaguchi, E.Minami, N.Shibuya, E.-U.Cho, N.Kobashi, H.Nojiri, T, Omori, M.Nishiyama, H.Yamane
- Journal Title
  
  Bioscience, Biotechnolnology, and Biochemistry 66
  
  Pages: 1140-1142
- NAID
  110002693794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12460051
[Presentation] 高度好熱菌Thermus thermophilusのリジン生合成におけるタンパク質間相互作用に関する研究2022
- Author(s)
  森田裕太郎、叶思言、吉田彩子、古園さおり、西山真
- Organizer
  2022年度日本農芸化学会　京都大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 放線菌由来1-azabicyclo[3.1.0]hexane環含有化合物におけるアジリジン環合成機構の解明2022
- Author(s)
  黒澤菫、長谷部文人、岡村仁則、吉田彩子、富田武郎、滝川浩郷、古園さおり、西山真
- Organizer
  2022年度日本農芸化学会　京都大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] マレイマイシン類生合成経路の解析2022
- Author(s)
  曽根祐輔、Muhammad Prima PUTRA、松田研一、古園さおり、西山真
- Organizer
  2022年度日本農芸化学会　京都大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 放線菌においてAmCPを介して生産される新規天然化合物の探索と同定2022
- Author(s)
  宮永寛哉、曽根祐輔、古園さおり、西山真
- Organizer
  2022年度日本農芸化学会　京都大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 高度好熱菌Thermus thermophilusのリジン生合成におけるLysVの機能解析2021
- Author(s)
  森田裕太郎、叶思言、吉田彩子、古園さおり、西山真
- Organizer
  2021年極限環境生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] AmCPを介して生合成される新規二次代謝産物の探索2021
- Author(s)
  宮永寛哉、曽根祐輔、吉田彩子、古園さおり、西山真
- Organizer
  生合成若手シンポジウム
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Studies on the biosynthetic machinery in secondary metabolism of Streptomyces to form 1-azabicyclo[3.1.0]hexane ring via aziridine ring2021
- Author(s)
  Sumire KUROSAWA, Kenichi MATSUDA, Fumihito HASEBE, Takeo TOMITA, Tomohisa KUZUYAMA, Saori KOSONO, Makoto NISHIYAMA
- Organizer
  日本農芸化学会　2021年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Type II AmCPを介した二次代謝産物の生合成2021
- Author(s)
  曽根祐輔、Muhammad Prima Putra、松田研一、古園さおり、西山真
- Organizer
  生合成若手シンポジウム
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 超好熱性アーキアにおけるリジン・アルギニン生合成2021
- Author(s)
  西山真
- Organizer
  日本農芸化学会　2021年度大会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] type II AmCPを介して生合成される新規アミノ酸の同定及び生合成に関する研究2021
- Author(s)
  曽根祐輔、Muhammad Prima PUTRA、松田研一、古園さおり、西山真
- Organizer
  日本農芸化学会　2021年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Streptomyces lydicusにおけるAmCPを介して生合成される新規化合物の探索2021
- Author(s)
  林勇太、曽根祐輔、吉田彩子、古園さおり、西山真
- Organizer
  2021年度(第35回)日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Serratia sp. ATCC 39006におけるアミノ基キャリアタンパク質を介した生合成についての研究2020
- Author(s)
  平島佑樹、曽根祐輔、菊池恒志郎、富田武郎、葛山智久、古園さおり、西山真
- Organizer
  日本農芸化学会　2020年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 放線菌の生産する抗細菌化合物Ficelomycinの生合成機構2020
- Author(s)
  西山真
- Organizer
  ビタミンB研究協議会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] typeII AmCPを介して生合成されるマレイマイシン類の生合成機構に関する研究2020
- Author(s)
  曽根祐輔、Muhammad Prima PUTRA、松田研一、葛山智久、古園さおり、西山真
- Organizer
  日本農芸化学会　2020年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 放線菌の生産するアザビシクロ環含有化合物vazabitide A生合成におけるアジリジン環合成経路に関する研究2020
- Author(s)
  黒澤菫、松田研一、長谷部文人、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会　2020年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 微生物は未知の物質変換系の宝庫である2019
- Author(s)
  西山真
- Organizer
  福井県立大学福井バイオインキュベーションセンター設立5周年記念特別講演会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Maleimycin Biosynthesis is mediated by Type II Amino-group Carrier Protein in Streptomyces sp.2019
- Author(s)
  Muhammad Prima Putra, Kenichi Matsuda, Takeo Tomita, Kazuo Shin-ya, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldarius由来のホモクエン酸合成酵素の構造・機能解析2019
- Author(s)
  鈴木智大、富田武郎、葛山智久、西山真
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Biosynthesis and modification of azabicyclo ring-containing compounds2019
- Author(s)
  Makoto Nishiyama
- Organizer
  2nd China-Japan Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] アザビシクロ環含有ジペプチドficellomycinの生合成機構に関する研究2019
- Author(s)
  黒澤菫、松田研一、長谷部文人、富田武郎、葛山智久、西山真
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Amino group carrier protein, a new platform in primary and secondary metabolite biosynthesis2018
- Author(s)
  Makoto Nishiyama
- Organizer
  2nd EFB-AFOB Joint Symposium on Applied Biocatalysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Discovery of unprecedented lysine biosynthesis using a carrier protein in Thermus thermophilus2018
- Author(s)
  Makoto Nishiyama
- Organizer
  International Workshop on 50th anniversary of Thermus thermophilus discovery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 放線菌の生産するアザビシクロ環含有化合物の生合成機構に関する研究2018
- Author(s)
  黒澤菫、西山真
- Organizer
  第9回醗酵学フォーラム
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] ficellomycin生合成におけるアザビシクロ環の修飾機構に関する研究2018
- Author(s)
  黒澤菫、松田研一、長谷部文人、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 微生物における生合成機能の多様性2018
- Author(s)
  西山　真
- Organizer
  第32回　バイオテクノロジー懇談会(応用微生物・分子細胞性物学研究奨励会)
- Invited
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldariusのホモクエン酸合成酵素の構造・機能及びフィードバック阻害機構の解析2018
- Author(s)
  鈴木智大、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Amino-group carrier protein, a new key machinery contributing to expansion of structural diversity of secondary metabolite2018
- Author(s)
  Makoto Nishiyama
- Organizer
  1st Japanese-German Symposium on Biosynthesis and Function of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Studies on Secondary Metabolic Pathway Mediated by Type II Amino-group Carrier Protein in Streptomyces sp.2018
- Author(s)
  M. Prima PUTRA , K. Matsuda, T. Tomita, K. Shin-ya, T. Kuzuyama, M. Nishiyama
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] ヒドラジンを生合成する酵素システムの発見2018
- Author(s)
  西山真
- Organizer
  第453回ビタミンB研究協議会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Amino-group carrier protein-mediated biosynthesi of primary and secondary metabolites2018
- Author(s)
  Makoto Nishiyama
- Organizer
  2018 Sino-Japan Symposium on Biocatalysis and Biotransformation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Discovery and biosynthetic characterization of a natural product biosynthesized via AmCP-mediated pathway2017
- Author(s)
  Kenichi Matsuda, Fumihito Hasebe, Yuh Shiwa, Yu Kanesaki, Takeo Tomita, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  Directing Biosynthesis V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Secondary metabolite biosynthesis mediated by amino-group carrier protein in Streptomyces2017
- Author(s)
  NISHIYAMA, Makoto
- Organizer
  Joint Symposium on Microbial Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 高度好熱菌Thermus thermophilus由来isopropylmalate synthaseのアシル化修飾による活性制御機構の解析2017
- Author(s)
  吉田彩子、吉田稔、古園さおり、西山　真
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Amino-group carrier protein mediated amino acid biosynthesis2017
- Author(s)
  NISHIYAMA, Makoto
- Organizer
  The 19th Japanese-German Workshop on Enzyme Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Studies on secondary metabolic pathway mediated by type II amino-group carrier protein (AmCP)in Streptomyces sp.2017
- Author(s)
  M. Prima Putra,K. Naito, K. Matsuda, T. Tomita, K. Shin-ya, T. Kuzuyama, M. Nishiyama
- Organizer
  日本放線菌学会2017年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Amino-group carrier protein mediated amino acid biosynthesis2017
- Author(s)
  Makoto Nishiyama
- Organizer
  The 19th Japanese-German Workshop on Enzyme Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Secondary metabolite biosynthesis mediated by amino-group carrier protein in Streptomycin2017
- Author(s)
  Makoto Nishiyama
- Organizer
  9th US-Japan Seminar on the Biosynthesis of Natural Products
- Place of Presentation
  UCLA Lake Arrowhead Conference Center
- Year and Date
  2017-05-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01465
[Presentation] Secondary metabolite biosynthesis mediated by amino-group carrier protein in Streptomyces2017
- Author(s)
  Makoto Nishiyama
- Organizer
  9th US-Japan Seminar on the Biosynthesis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] atural compound biosynthesis mediated by amino-group carrier protein: discovery of novel N-N bond forming enzyme system2017
- Author(s)
  Makoto Nishiyama
- Organizer
  New Trends in Enzyme and Microbial Science in the Translational Biology Era
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] Secondary metabolite biosynthesis mediated by amino-group carrier protein in Streptomyces2017
- Author(s)
  NISHIYAMA, Makoto
- Organizer
  9th US-Japan Seminar on the Biosynthesis of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 新規天然化合物s56-p1の特異なヒドラゾンユニットの生合成に関する研究2017
- Author(s)
  松田研一、新家一男、葛山智久、西山　真
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 放線菌におけるアミノ基キャリアタンパク質を介して生合成される非タンパク性アミノ酸の修飾機構に関する研究2017
- Author(s)
  黒澤菫, 松田研一, 長谷部文人, 葛山智久, 西山真
- Organizer
  日本放線菌学会2017年度大会
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] 新規非タンパク性アミノ酸DADHによる免疫抑制作用2017
- Author(s)
  関本崇弘、八代拓也、長谷部文人、松田研一、笠倉和巳、西山　真、西山千春
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 好熱菌Thermus thermophilus由来のリジン生合成系酵素LysKとキャリアタンパク質LysWの相互作用機構に関する研究2017
- Author(s)
  藤田理美、長谷部文人、CHO Su-Hee、富田武郎、葛山智久、西山　真
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 新規アミノ酸DADHによるマスト細胞の活性抑制2017
- Author(s)
  白井智丈、笠倉和巳、長谷部文人、松田研一、八代拓也、西山　真、西山千春
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldariusにおけるアルギニン生合成酵素遺伝子の転写調節機構に関する研究2017
- Author(s)
  中西史佳、富田武郎、葛山智久、西山　真
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Streptomyces sp. SpE090715-01 produces a maleimycin-like compound using amino-group carrier protein (AmCP)2017
- Author(s)
  Muhammad Prima PUTRA, Naito KAZUHIRO, Matsuda KENICHI, Tomita TAKEO, Shin-ya KAZUO, Kuzuyama TOMOHISA, Nishiyama MAKOTO
- Organizer
  日本農芸化学会2017年度大会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Secondary metabolite biosynthesis mediated by amino-group carrier protein in Streptomyces2017
- Author(s)
  Makoto Nishiyama
- Organizer
  Joint Symposium on Microbial Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06168
[Presentation] アミノ基結合型キャリアタンパク質を介したリジン生合成メタボロンの解析2016
- Author(s)
  清水　哲、富田武郎、葛山智久、西山　真
- Organizer
  生命システム原材料の起源と進化研究会
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] AmCP-mediated lysine biosynthesis and regulation2016
- Author(s)
  Makoto Nishiyama
- Organizer
  The Fifth International Symposium on Cofactors & Active Enzyme Molecule 2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 枯草菌ECFシグマ因子SigXのグルコース依存的な活性化に関わるRNAポリメラーゼのアセチル化2016
- Author(s)
  米沢祐大、小倉光雄、鈴木祥太、吉田彩子、浅井計、吉田稔、西山真、古園さおり
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26870113
[Presentation] アミノ基キャリアタンパク質を介したリジン生合成酵素LysYの基質認識機構の構造基盤2016
- Author(s)
  清水哲、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] AmCP-mediated lysine biosynthesis and its regulation in thermophiles2016
- Author(s)
  Makoto Nishiyama
- Organizer
  The 11th International Congress on Extremophiles
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基キャリアタンパク質を介する生合成：発見と普遍性2016
- Author(s)
  西山　真
- Organizer
  東京理科大学　アグリ・バイオ公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ酸キャリアタンパク質(AmCP)を介して生合成されるアミノ酸DADH修飾酵素の同定2016
- Author(s)
  長谷部文人、松田研一、白石太郎、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基キャリアタンパク質を介した多様な化合物の生合成2016
- Author(s)
  西山　真
- Organizer
  静岡県立大学　食糧栄養科学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基キャリアタンパク質を指標とした新規天然化合物の探索及びその生合成に関する研究2016
- Author(s)
  松田研一、長谷部文人、富田武郎、志波優、兼崎友、吉川博2、新家一男、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基結合型キャリアタンパク質を介した二次代謝生合成機構の解明と新規有用生物活性物質の探索2016
- Author(s)
  西山　真
- Organizer
  公益財団法人　日本応用酵素協会　酵素研究助成　研究発表会
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ酸代謝関連酵素の構造・機能・調節2016
- Author(s)
  西山　真
- Organizer
  浅野酵素活性分子プロジェクト研究成果報告会
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] II型アミノ基キャリアタンパク質を介した二次代謝産物の生合成に関する研究2016
- Author(s)
  内藤一洋、松田研一、長谷部文人、富田武郎、手塚武揚、大西康2、志波優、吉川博文、新家一男、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Corynebacterium glutamicum由来ホスホエノールピルビン酸カルボキシラーゼ(PEPC)のアセチル化制御はグルタミン酸生産に重要である2016
- Author(s)
  永野愛、山田鮎果、水野裕太、菊池正樹、白水美香子、梅原崇史、吉田彩子、吉田稔、西山真、古園さおり
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26870113
[Presentation] アミノ基結合型キャリアタンパク質を指標とした探索による新規天然化合物s56-p1発見とその生合成に関する研究2016
- Author(s)
  松田研一、西山　真
- Organizer
  第7回　醗酵学フォーラム
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Analysis of protein acylation on enzymes involved in branched-chain amino acid in Thermus thermophilus2016
- Author(s)
  Ayako Yoshida, Makoto Nishiyama, Minoru Yoshida, and Saori Kosono
- Organizer
  The 11th International Congress on Extremophiles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Thermus thermophilusにおいてアセチル化を受けるCoAトランスフェラーゼの機能と制御機構の解析2016
- Author(s)
  山本寛之、吉田彩子、富田武郎、古園さおり、葛山智久、西山真
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-26870113
[Presentation] アミノ酸生合成系における反応の共通性と普遍性2016
- Author(s)
  西山　真
- Organizer
  第89回　日本生化学会　フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 放線菌におけるアミノ基キャリアタンパク質を介した二次代謝産物生合成2014
- Author(s)
  西山真
- Organizer
  日本放線菌学会2014年度大会　基調講演
- Place of Presentation
  筑波
- Year and Date
  2014-06-19
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Biosynthetic machinery of secondary metabolites using amino acid carrier protein in Streptomyces2013
- Author(s)
  Fumihito Hasebe, Takeo Tomita, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  17th German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  Technical University of Hamburg-Harburg
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] N-protecting protein LysW functions as a carrier protein in lysine biosynthesis on Thermus thremophilus2013
- Author(s)
  Ayako Yoshida, Takeo Tomita, Saori Kosono, Tomohisa Kuzuyama, Makoto Nishiyama
- Organizer
  17th German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  Technical University of Hamburg-Harburg
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Carrier protein-mediated amino acid biosynthesis2013
- Author(s)
  Makoto Nishiyama
- Organizer
  17th German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  Technical University of Hamburg-Harburg
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Lysine and arginine biosynthesis in thermococcus kodakarensis2013
- Author(s)
  Ayako Yoshida, Makoto Nishiyama
- Organizer
  Enzyme Technology XXII
- Place of Presentation
  富山国際会議場
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] リジン・アルギニン生合成機構と進化の解明に向けて2012
- Author(s)
  西山真
- Organizer
  日本農芸化学会2012年度大会シンポジウム
- Place of Presentation
  京都市、京都
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Thermococcus kodakarensisにおけるリジン・アルギニン生合成経路の解析2012
- Author(s)
  吉田彩子、西山真
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都市、京都
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Analysis of substrate specificity of homoisocitrate dehydrogenase homolog from Thermococcus kodakarensis2012
- Author(s)
  Yin Lulu、西山真
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都市、京都
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] リジン・アルギニン生合成機構と進化の解明に向けて2012
- Author(s)
  西山真
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(招待講演)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] リジン・アルギニン生合成系の共通起源と進化2011
- Author(s)
  西山真
- Organizer
  第84会日本生化学会大会シンポジウム
- Place of Presentation
  京都市、京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] リジン/アルギニン生合成系の共通祖先および進化の解明に向けて2011
- Author(s)
  西山真
- Organizer
  日本農芸化学会2011年度大会シンポジウム
- Place of Presentation
  京都女子大学、京都
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Directed evolution of homoisocitrate dehydrogenase to 3-isopropylmalate dehydrogenase2011
- Author(s)
  西山真
- Organizer
  IUMS2011 Congress
- Place of Presentation
  札幌、北海道
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] リジン・アルギニン生合成系の共通起源と進化2011
- Author(s)
  西山真
- Organizer
  日本生化学会2012年度大会
- Place of Presentation
  京都国際会議場(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] アミノ酸生合成系のパッチワーク仮説2011
- Author(s)
  西山真
- Organizer
  理研シンポジウム:生命システム原材料の起源と進化
- Place of Presentation
  東京
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase2011
- Author(s)
  西山真
- Organizer
  16th Japanese-German Workshop on enzyme Technology
- Place of Presentation
  富山、富山
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Thermus thermophilusのリジン生合成酵素LysZおよびキャリアタンパク質の構造機能解析2010
- Author(s)
  吉田彩子、西山真
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  駒場、東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] グルタミン酸脱水素酵素の新規活性調節機構の発見2010
- Author(s)
  西山真、富田武郎
- Organizer
  日本農芸化学会2010年度大会シンポジウム
- Place of Presentation
  駒場、東京
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] アミノ酸生合成におけるタンパク質によるアミノ基修飾の普遍性2010
- Author(s)
  西山真
- Organizer
  東京大学生物生産工学研究センターシンポジウム
- Place of Presentation
  文京区、東京
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Carrier protein-mediated lysine/arginine biosynthesis in thermophile2010
- Author(s)
  西山真
- Organizer
  Japanese-Swiss Meeting on Biotechnology & Bioprocess Development
- Place of Presentation
  富山市、富山
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] IPMDH活性を示すよう分子進化させた改変HICDHの構造と機能2010
- Author(s)
  鈴木夢生、西山真
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  駒場、東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] アミノ酸生合成酵素の構造・機能・活性制御に関する基礎・応用研究2010
- Author(s)
  西山真
- Organizer
  第11回酵素応用シンポジウム
- Place of Presentation
  名古屋、愛知
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] グルタミン酸脱水素酵素の新規活性調節機構の発見2010
- Author(s)
  西山真、富田武郎
- Organizer
  日本農芸化学会2010年度大会シンポジウム「酵素・タンパク質のユニークな活性調節機構および機能発現の新展開」
- Place of Presentation
  東京大学
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] 高度好熱菌Thermus thermophilus由来ホモクエン酸合成酵素の活性調節機構の解析2010
- Author(s)
  岡田卓也、西山真
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京、駒場
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] アミノ酸生合成・代謝の調節機構:構造生物学的な視点から2010
- Author(s)
  西山真
- Organizer
  東北大学サテライトシンポジウム
- Place of Presentation
  仙台、宮城
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] リジン生合成の調節機構2010
- Author(s)
  西山真
- Organizer
  千葉大学COEスタートアッププログラムシンポジウム「代謝変換プログラムの生体制御への応用」
- Place of Presentation
  千葉大学
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] 旧くて新しいアミノ酸生合成研究2009
- Author(s)
  西山真
- Organizer
  富山県立大学生物工学研究センター講演会
- Place of Presentation
  富山県立大学、富山
- Year and Date
  2009-12-22
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Carrier protein-mediated amino acid biosynthesis2009
- Author(s)
  Nishiyama, M.
- Organizer
  15^<th> German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  ドイツ・ロストック大学
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] 好熱菌のユニークなリジン生合成系と酵素の構造および機能2009
- Author(s)
  西山真
- Organizer
  筑波大学プレ戦略イニシアティブシンポジウム「微生物の"生体と生態"研究の最前線」
- Place of Presentation
  筑波大学
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] 好熱菌のユニークなリジン生合成と酵素の構造および機能2009
- Author(s)
  西山真
- Organizer
  「微生物の"生体と生態"研究の最前線」シンポジウム
- Place of Presentation
  筑波大学、筑波
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] 旧くて新しいアミノ酸生合成研究2009
- Author(s)
  西山真
- Organizer
  富山県立大学生物工学研究センター講演会
- Place of Presentation
  富山県立大学
- Year and Date
  2009-12-22
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] アーキアのリジン・アルギニン・ロイシン生合成酵素の構造・機能・進化
- Author(s)
  西山　真
- Organizer
  日本農芸化学会シンポジウム
- Place of Presentation
  東北大学（仙台）
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基修飾型キャリアタンパク質を介した二次代謝産物の生合成
- Author(s)
  西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基結合型キャリアタンパク質を指標とした新規天然化合物の探索
- Author(s)
  松田研一、長谷部文人、富田武郎、志波優、吉川博文、新家一男、葛山智久、西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Origin of lysine and arginine biosynthesis
- Author(s)
  Makoto Nishiyama
- Organizer
  Enzyme Technology XXII
- Place of Presentation
  富山国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Function and regulation of enzymes involved in amino acid biosynthesis of Sulfolobus acidocaldarius
- Author(s)
  Takeo Tomita, Kento Takahashi, Nagisa Akiyama, and Makoto Nishiyama
- Organizer
  第4回モデル生物丸ごと一匹学会
- Place of Presentation
  大阪
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] リジン生合成系の起源と進化
- Author(s)
  西山　真
- Organizer
  電気通信大学生命科学シンポジウム「生命システム原材料の起源と進化：生化学的禁制律」
- Place of Presentation
  電気通信大学（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Secondary metabolites biosynthesized using AmCP, a novel amino acid carrier protein, in Actinomycetes
- Author(s)
  Kenichi Matsuda, Fumihito Hasebe, Takeo Tomita, Yu Shiwa, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  Japan-Italy Symposium
- Place of Presentation
  Nara
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 古細菌Sulfolobus acidocaldariusのアミノ酸生合成経路を構成する酵素の機能・構造解析
- Author(s)
  富田武郎、高橋賢人、秋山　渚、西山　真
- Organizer
  第15回極限環境生物学会
- Place of Presentation
  沖縄
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Characterization of an ancestral-type β-decarboxylating dehydrogenase from Thermococcus kodakarensis
- Author(s)
  Tetsu Shimizu, Lulu Yin, Kento Takahashi, Takeo Tomita, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  第4回モデル生物丸ごと一匹学会
- Place of Presentation
  大阪
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 原始型β脱炭酸脱水素酵素の機能と構造基盤
- Author(s)
  清水　哲、伊　録録、高橋賢人、富田武郎、葛山智久、西山　真
- Organizer
  第5回醗酵学フォーラム
- Place of Presentation
  湯河原
- Year and Date
  2014-11-23 – 2014-11-24
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Analysis of protein acylation on metabolic enzymes and acyltransferase in Thermus thermophilus HB27
- Author(s)
  吉田彩子、山本寛之、富田武郎、西山真、吉田稔、古園さおり
- Organizer
  第四回モデル生物丸ごと一匹学会
- Place of Presentation
  大阪大学（大阪府豊中市）
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26870113
[Presentation] 超好熱・好酸性古細菌Sulfolobus acidocaldariusにおけるアミノ酸生合成経路の調節機構の解析
- Author(s)
  秋山渚、富田武郎、葛山智久、西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Thermococcus kodakarensis由来の祖先型β-脱炭酸脱水素酵素の機能と構造基盤の解析
- Author(s)
  清水　哲、伊　録録、高橋賢人、富田武郎、葛山智久、西山　真
- Organizer
  第15回極限環境生物学会
- Place of Presentation
  沖縄
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Screening of secondary metabolites biosynthesized with novel amino acid carrier protein system
- Author(s)
  Kenichi Matsuda, Fumihito Hasebe, Takeo Tomita, Yu Shiwa, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  2014 ASBMB Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 高度好熱菌Thermus thermophilusにおける短鎖アシル化修飾による分岐鎖アミノ酸生合成酵素の調節
- Author(s)
  吉田彩子、西山真、吉田稔、古園さおり
- Organizer
  第15回極限環境生物学会年会
- Place of Presentation
  今帰仁村コミュニティーセンター（沖縄県今帰仁村）
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-26870113
[Presentation] アミノ酸キャリアタンパク質を介して生合成される新規アミノ酸とその代謝産物の同定
- Author(s)
  長谷部文人、富田武郎、高ひかり、藤村努、西山千春、葛山智久、西山真
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田校舎
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] アミノ基結合型キャリアタンパク質を指標とした新規天然化合物の探索
- Author(s)
  松田研一、長谷部文人、富田武郎、志波　優、吉川博文、新家一男、葛山智久、西山真
- Organizer
  第49回天然物化学談話会
- Place of Presentation
  倉敷
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 高度好熱菌Thermus thermophilusにおけるタンパク質アセチル化酵素及び標的タンパク質の同定と機能解析
- Author(s)
  山本寛之、吉田彩子、富田武郎、古園さおり、葛山智久、西山真
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26870113
[Presentation] アミノ酸キャリアタンパク質を介して生合成される新規アミノ酸とその代謝産物の同定
- Author(s)
  長谷部文人、富田武郎、高ひかり、藤村　務、西山千春、葛山智久、西山　真
- Organizer
  第49回天然物化学談話会
- Place of Presentation
  倉敷
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Structure and function of an ancestral-type β-decarboxylating dehydrogenase from Thermococcus kodakarensis
- Author(s)
  Tetsu Shimizu, Lulu Yin, Kento Takahashi, Takeo Tomita, Tomohisa Kuzuyama, and Makoto Nishiyama
- Organizer
  Active Enzyme Molecule 2014
- Place of Presentation
  Toyama
- Year and Date
  2014-12-17 – 2014-12-19
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] 多基質に活性を示すβ－脱炭酸脱水素酵素の構造基盤
- Author(s)
  西山　真
- Organizer
  第437回ビタミンB研究協議会
- Place of Presentation
  山口
- Year and Date
  2014-09-05 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24228001
[Presentation] Carrier-protein mediated amino acid biosynthesis
- Author(s)
  西山真
- Organizer
  15th German-Japanese Workshop on Enzyme Technology
- Place of Presentation
  Rostoc, Germany
- Data Source
  KAKENHI-PROJECT-21380057
[Presentation] Amino acid-carrier protein-mediated biosynthesis of biomolecules
- Author(s)
  Makoto Nishiyama
- Organizer
  Japan-Italy Symposium
- Place of Presentation
  Nara
- Year and Date
  2014-11-05 – 2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-24228001

1. HORINOUCHI Sueharu (80143410)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. TOMITA Takeo (50447364)

# of Collaborated Projects: 5 results

# of Collaborated Products: 59 results
3. YAMANE Hisakazu (80090520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. Yoshida Ayako (90633686)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. TANOKURA Masaru (60136786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SASAKI Hiroshi (80272467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OMORI Toshio (20011984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NOJIRI Hideaki (90272468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOSONO Saori (90321760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. 別府輝彦 (80011873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. WAKIMOTO Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 葛山智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 田中寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中野雄司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishiyama Makoto 西山 真

NISHIYAMA Makoto 西山 真

Research Projects

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Co-Researchers

Studies on mining of novel enzymes functioning in secondary metabolite biosynthesis in Streptomyces and their molecular mechanism.Principal Investigator

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Studies on mechanisms of biosynthesis of biomolecules via amino-group carrier protein and expansion of structural diversity of secondary metabolitesPrincipal Investigator

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Elucidation of structures and functions of metabolic enzymes of lysine and related compounds and their molecular evolutionPrincipal Investigator

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Elucidation of mechanisms of biomaterial conversion mediated by amino group-modifying carrier protein and applicationPrincipal Investigator

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リジン生合成および関連一次代謝系酵素群の機能および分子進化の解析Principal Investigator

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Structural biology for elucidation of lysine biosynthesis and its regulatory mechanismsPrincipal Investigator

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Structure-function relationship of novel lysine biosynthetic enzymes and analysis of molecular evolution of the pathwayPrincipal Investigator

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Analysis of novel lysine biosynthesis in Thermus and its regulationPrincipal Investigator

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Analysis of mechanisms of regulation of aspartate kinase and lysine biosyntheseis in Thermus thermophilusPrincipal Investigator

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耐熱性リンゴ酸脱水素酵素のドメインの折れたたみ機構に関する研究Principal Investigator

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Principal Investigator

Nishiyama Makoto 西山真

NISHIYAMA Makoto 西山真