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Tanokura Masaru  田之倉 優

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… Alternative Names

TANOKURA Masaru  田之倉 優

田野倉 憂  タノクラ マサル

島田 達生

田之倉 優

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Researcher Number 60136786
Other IDs
External Links
Affiliation (Current) 2022: 東京大学, 大学院農学生命科学研究科(農学部), 名誉教授
Affiliation (based on the past Project Information) *help 2017 – 2020: 東京大学, 大学院農学生命科学研究科(農学部), 特任教授
2017: 東京大学, 農学生命科学研究科, 特任教授
2015 – 2016: 東京大学, 大学院農学生命科学研究科(農学部), 教授
2015: 東京大学, 大学院農学生命科学研究科, 教授
2011 – 2015: 東京大学, 農学生命科学研究科, 教授 … More
2011: 東京大学, 大学院・農学生命科学研究科, 教授
2006: The University of Tokyo, Faculty of Agriculture, Professor, 大学院・農学生命科学研究科, 教授
2005 – 2006: 東京大学, 大学院農学生命科学研究科, 教授
2004: the University of Tokyo, Graduate School of Agricultural and Life Science, Professor, 大学院・農学生命化学研究科・応用生命化学専攻, 教授
2004: 国立大学法人東京大学, 大学院・農学生命化学研究科応用生命化学専攻, 教授
2004: 東京大学, 農学生命科学研究科・応用化学専攻, 教授
1998 – 2004: 東京大学, 大学院・農学生命科学研究科, 教授
2003: 東京大学, 大学院・農学生命科学研究科・応用化学専攻, 教授
1994 – 1997: The Univ.of Tokyo, Biotechnology Research Center, Professor, 生物生産工学研究センター, 教授
1996: 東京大学, 生物生産工学センター, 教授
1995: 東京大学, 農学部, 教授
1994: The University of Tokyo Biotechnology Research Center Professor, 生物生産工学センター, 教授
1994: 東京大学, 生物生産工学研究セ, 教授
1993: 東京大学, 大学院・理学系研究科, 助教授
1989 – 1991: 東京大学, 理学部, 講師
1989: Med.Col.Oita, Physiology, assistant (1987), 医学部(昭和62年度), 助手
1987: 大分医科大学, 医学部, 助手
1987: 大分医科大学, 医学部・解剖学, 助教授 Less
Review Section/Research Field
Principal Investigator
Biophysics / Biological Sciences / Structural biochemistry / Food science / 生物物性学 / 食品科学・栄養科学 / Structural biochemistry / Applied biochemistry
Except Principal Investigator
Structural biochemistry / Applied microbiology … More / 物質生物化学 / Structural biochemistry / Bioproduction chemistry/Bioorganic chemistry / Otorhinolaryngology / Neurophysiology and muscle physiology / Pathological medical chemistry / Neurosurgery / Morphology/Structure / Basic Section 53020:Cardiology-related / Pathological medical chemistry Less
Keywords
Principal Investigator
NMR / X線結晶構造解析 / 核磁気共鳴法 / ミオシン / ATPase / 酸性プロテアーゼA / フラビン還元酵素 / 発光細菌 / 核磁気共鳴 / 反応中間体 … More / サブフラグメント1 / 酸性プロテアーゼ / クロコウジカビ / 非ペプシン型酸性プロテアーゼ / 蛋白質工学 / 遺伝子クローニング / 発現系 / システインプロテアーゼ / 発光関連酵素 / ニトロ還元酵素 / 発光反応 / 老化 / ミトコンドリア / Nuclear magnetic resonance / X-ray crystallography / アクトミオシン / X線小角散乱 / Kratky plot / X線非結晶構造解析 / ブロメラインインヒビター / システインプロテアーゼインヒビター / ncd / キネシン / CD / 円二色性 / coiled coil / ブロメライン インヒビター / インヒビター / 生物発光 / モノオキシゲナーゼ / X線結晶撞造解析 / WWドメイン / 表面プラズモン共鳴 / 分子モデリング / シグナル伝達 / 相互作用解析 / プロリン・リッチ配列 / リン酸化 / アルツハイマー病 / 抗老化 / 食品 / 食物質 / ミトコンドリ / Myosin / Reaction intermediates / Subfragment 1 / 非ペプシン型 / 3次元構造解析 / 構造解析 / 3次元構造 / Acid proteinase / Non-pepsin-type / x-ray crystallography / Three-dimensional structural analysis / Structural analysis / 平滑筋 / モーター蛋白質 / モータータンパク質 / myosin / smooth muscle / motor protein / nuclear magnetic resonance / 生物マシーナリー / シンクロトロン放射光 / 構造生物学 / 生体高分子複合体 / 生体高分子集合系 / 膜タンパク質 / X線結晶学 / 蛋白結晶学 / 超分子複合体 / 膜蛋白質 / Biological machineries / Synchrotron radiation / Structural biology / Complex of biomacromolecules / Group of biomacromolecules / membrane proteins / 阻害活性 / 基質特異性 / 酵素反応速度論 / フラビン / 変異体 / Flavin Reductase / Nitro Reductase / Inhibition Activity / Substrate Specificity / X-Ray Crystallography / Enzyme Reaction Kinetics / シスタチン / プロテアーゼインヒビター / ダイマー-モノマー変換 / 機能構造相関 / 核磁気共鳴(NMR) / 新機能性食品 / オリザシスタチン / プロテアーゼ阻害剤 / モネリン / 甘味タンパク質 / キメラタンパク質 / 結晶化 / 二量体化 / cystatin / protease inhibitor / dimer-monomer conversion / structure-function correlation / nuclear magnetic resonance (NMR) / new functional food / ^<31>P-NMR / プローブ / リン酸結合タンパク質 / In vivo NMR / プローブ開発 / 生きた細胞 / in vivo NMR / リンNMR / シグナル云達 / ^<31>P NMR / Probe / Phosphate binding protein / 代謝動態 / 線虫 / 寿命 … More
Except Principal Investigator
糖タンパク質 / 受精 / 透明帯 / NMR / X線結晶構造解析 / ラウエ法 / 細胞外マトリクス / 自己触媒的活性化 / X線結晶解析 / Proctase A / desulfurization / dibenzothiophene / Rhodococcus erythropolis / desulfinase / DszB / DszC / Bfl / HR-HMBC / BIRD-J-resolved HMBC / caged ATP / ATP / 進化 / 時間分割解析 / 蛋白質の構造 / 蛋白質の動的構造 / NMR分光法 / 緩和時間測定 / ケージ化合物 / 大腸菌 / ATP依存性プロテアーゼ / 超遠心分析 / 細胞外マトリックス / 小角X線散乱 / カルボキシルプロテア-ゼ / 酸性プロテア-ゼ / プロクタ-ゼA / カテプシンE / コピアプロテア-ゼ / 粘菌酸性プロテア-ゼ / プロテア-ゼ前駆体 / 水溶性カルボジイミド / 基質特異性 / cDNA / 遺伝子 / トランスポゾンプロテア-ゼ / 粘菌プロテア-ゼ / ペプシノ-ゲン / Carboxyl protease / Acid protease / Cathepsin E / Copia protease / Physarum acid protease / Protease precursor / Autocatalytic activation / 放射光利用 / 蛋白質3次元構造 / ダイナミックス / 時分割ラウエ / シンポジウム / 報告書 / News Letter / 動的構造研究会 / 蛋白質結晶構造 / ニュースレター / photon Factory / 国際 / Photon Factory / 放射光 / ミリ秒オーダー / 原子レベル / 動的構造 / Time resolved Laue / millisecond / Synchrotron Radiation / process of reaction / white x-ray / dynamic protein structure / time resolution / X-ray analysis / プロクターゼA / プロクターゼB / カルボキシルプロテアーゼ / 部位特異的変異導入法 / 活性中心アスパラギン酸残基 / カルボキシル プロテアーゼ / 活性中心カルボキシル基 / 前駆体活性化 / 部位指定突然異導入法 / アスパラギン酸プロテアーゼ / 部位指定突然変異導入法 / Proctase B / carboxyl proteinase / site-directed mutagenesis / autocatalytic activation / active site asparticacid residue / X-ray crystallography / 食品 / 免疫学 / 腸内フローラ / γδT細胞 / 腸管上皮細胞T細胞 / 分泌型IgA抗体 / クリプトパッチ / 孤立リンパ小節 / 経口免疫寛容 / 炎症性腸疾患 / 腸管上皮細胞間T細胞 / 生体分子 / トランスレーショナルリサーチ / 腸管孤立リンパ小節 / 分泌型lgA抗体 / 腸内常在フローラ / 腸管上皮細胞 / 樹状細胞 / インターロイキン15 / Heme oxygenase / 一酸化炭素 / dietary substances / immunology / intestinal flora / γδ T cells / intestinal T cells / secretory IgA antibody / cryptopatch / isolated lymphoid follicles / 孵化酵素 / メダカ / 3次元構造 / 卵膜分解 / アスタシンファミリー / 軟骨魚類 / アスタシン / タンパク質分解酵素 / タンパク質立体構造 / 卵膜分解機構 / Hatching enzyme / Three dimensional structure / Medaka / Olyzias latipes / Astacin family / Teleost / DszA / BdsA / desuofurization / Bds / HR(High Resolution)-HMBC / HMBC / J-scaling / DNAマイクロアレイ / プロテオミクス / 蝸牛 / 内耳 / 老人性難聴 / 老化 / ミトコンドリア / ミトコンドリアDNA / カロリー制限 / DNAチップ / 難聴 / 音響外傷 / DNA MICROARRAY / PROTEOMICS / GCOCHLEA / INNER EAR / PRESBYCUSIS / AGING / 脱鞘筋線維 / ルビ-レ-ザ / 筋のスティフネス / クロスブリッジ / エチレングリコ-ル / 筋の張力 / Caged ATP / 収縮の動力学 / エチレングリコール / ルビーレーザ / グリセリン処理筋 / アクトミオシン / リン核磁気共鳴法 / skinned muscle fiber / Ruby laser / muscle stiffness / cross-bridge / ethylene glycol / active tension of muscle / 低比重リポ蚕白(LDL) / LDLレセプター / LDLレセプター構造変異 / コレステロール代謝異常 / 糖鎖構造変異 / マクロファージ / 泡沫化細胞 / 低比重リポ蛋白(LDL) / 糖鎖構造異変 / 体細胞遺伝変異 / 低比重リポ蛋白レセプター不全 / ゴルジ装置 / Low density lipoprotein / LDL receptor / LDL receptor mutation / Cholesterol metabolic disorders / Carbohydrate chain mutation / Macrophage / MUSE細胞 / 幹細胞 / 神経分化誘導 / BCボックスモチーフ / 再生医療 / BCボックスモチーフ / VHL / JAK/STAT / 多能性組織幹細胞 / 皮膚由来前駆細胞 / 体性幹細胞 / 神経再生医療 / VHL / 神経分化誘導ペプチド / 多能性体性幹細胞 / BC-boxモチーフ / 多能性幹細胞 / 神経再生 / カラクシン / 鞭毛 / 繊毛 / 精子 / ダイニン / 微小管 / 生殖 / 繊毛病 / 鞭毛繊毛 / カルシウム / オピストコンタ / 神経カルシウムセンター / 形態形成 / 神経カルシウムセンサー / スフィンゴモナス / 環境汚染物質 / 可動性遺伝因子 / ゲノム / Sf9細胞 / タンパク質複合体 / バキュロウイルス / 平滑筋ミオシン / 家族性大動脈解離 / 血管老化機構 / 神経変性疾患 / アルツハイマー病 / ALS / キサンチン脱水素酵素 / XOR阻害剤 / XOR酵素阻害剤 / 阻害剤による治療薬 / キサンチン酸化還元酵素 / プリンサルベージ回路 / 高尿酸血症治療薬 / 筋萎縮性側索硬化症 / タンパク質凝集 / 抗高尿酸血症治療薬 / キサンチン酸化酵素 Less
  • Research Projects

    (39 results)
  • Research Products

    (136 results)
  • Co-Researchers

    (113 People)
  •  Molecular mechanism of familial aortic dissection by smooth muscle myosin mutation and elucidation of vascular aging mechanism

    • Principal Investigator
      永井 良三
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Jichi Medical University
  •  Analysis of age-related metabolic changes in mitochondria of Caenorhabditis elegansPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied biochemistry
    • Research Institution
      The University of Tokyo
  •  Neuronal differentiation of MUSE cells mediated by neuronal differentiation control peptides and application to neuronal regeneration medicine

    • Principal Investigator
      Kanno Hiroshi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      International University of Health and Welfare
      Yokohama City University
  •  Sperm recognition domain in mammalian egg coat matrix

    • Principal Investigator
      Yonezawa Naoto
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Chiba University
  •  Mechanism of effectof XOR inhibitors on delay of progress of neurodegenerative diseases

    • Principal Investigator
      Nishino Takeshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tokyo Health Sciences
      The University of Tokyo
  •  Regulatory mechanism of ciliary functions by calaxin

    • Principal Investigator
      Inaba Kazuo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphology/Structure
    • Research Institution
      University of Tsukuba
  •  Mechanisms for acquiring ability to degrade novel compounds in sphingomonads and their applications

    • Principal Investigator
      Nagata Yuji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied microbiology
    • Research Institution
      Tohoku University
  •  Sperm recognition domain in mammalian egg coat matrix

    • Principal Investigator
      YONEZAWA Naoto
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Chiba University
  •  Elucidation of aging regulatory mechanisms related to mitochondrial function and identification of anti-aging food factorsPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Food science
    • Research Institution
      The University of Tokyo
  •  Sperm recognition and matrix formation mechanisms of mammalian egg coats

    • Principal Investigator
      YONEZAWA Naoto
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Chiba University
  •  ANALYSIS OF GENES AND PROTEINS RELATED TO COCHLEAR DAMAGE USING DNA MICROARRAY AND PROTEOMICS

    • Principal Investigator
      YAMASOBA Tatsuya
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      The University of Tokyo
  •  WWドメインの機能と特異性に関する総合理解を目指した構造構能相関研究Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Three dimensional structures of HCE and LCE and its mechanism of egg envelope digestion

    • Principal Investigator
      YASUMASU Shigeki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Sophia University
  •  Improvement of Functions of Novel Enzymes in the Desulfurization Metaoblism of Petroleum by Protein Engineering and Molecular Genetics

    • Principal Investigator
      IZUMI Yoshikazu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied microbiology
    • Research Institution
      National University Corporation Tottori University
  •  New Methods for Measuring Heteronuclear Long Range Coupling Constants and Proton-Proton Coupling Constants

    • Principal Investigator
      FURIHATA Kazuo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      The University of Tokyo
  •  Analysis of structure-function correlation of oryzacystatin and development of new functional foodsPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      The University of Tokyo
  •  Development of the ^<31>P-NMR Probe with ultra high sensitivity and analysis of phosphate binding proteins, related to signal transductionPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Investigation of immuno-regulatory competency of dietary substances and its application for our own beneficial ends

    • Principal Investigator
      ISHIKAWA Hiromichi
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Keio University
  •  発光細菌の発光反応関連酵素群のX線結晶構造解析Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  X-Ray Crystallography of Flavin Reductase and Its MutantsPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  X線とNMRによるクロコウジカビ酸性プロテアーゼAの折れたたみ機構の解析Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  ブロメラインインヒビターの3次元構造解析とそれに基づく阻害剤の開発Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Structural Biology of Biological Machineries through X-ray Protein Crystallography Reinforced by Synchrotron RadiationPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru, 三井 幸雄
    • Project Period (FY)
      1998 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Nagaoka University of Technology
  •  NMRとX線によるクロコウジカビ酸性プロテアーゼAの折れたたみ機構の解析Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ブロメラインインヒビターの3次元構造解析とそれに基づく阻害剤の開発Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  キネシンとncdのNMRによる動的構造の解析Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analysis of structure-function relationships on smooth muscle myosin using NMR and X-ray crystallography.Principal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biophysics
    • Research Institution
      University of Tokyo
  •  NMRとX線によるクロコウジカビ酸性プロテアーゼAの折れたたみ機構の解析Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  NMRとX線小角散乱によるクロコウジカビ酸性プロテアーゼAの折れたたみ機構の解析Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  大腸菌ATP依存性プロテアーゼLonの構造と機能

    • Principal Investigator
      高橋 健治
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  時間分割ラウエ法利用研究

    • Principal Investigator
      MITSUI Yukio
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagaoka University of Technology
  •  Millisecond Order Dynamics of Protein Crystal Structure Using Syncrotron Radiation.

    • Principal Investigator
      SAKABE Noriyoshi
    • Project Period (FY)
      1993 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Foundation for Advancement of International Science
      University of Tsukuba
      高エネルギー物理学研究所
  •  Studies on Carboxyl Proteinases : Comparative Analysis of Functional Structures and Catalytic Mechanisms of Proctases A and B

    • Principal Investigator
      TAKAHASHI Kenji
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Three-dimensional structural analysis of non-pepsin-type acid proteinase using NMR and x-ray crystaliographyPrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  りん核磁気共鳴法によるアクトミオシン反応中間体の立体構造の研究Principal Investigator

    • Principal Investigator
      田之倉 優
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Studies on the molecular properties and the structure-function relationships of carboxyl proteases of novel type

    • Principal Investigator
      TAKAHASHI Kenji
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      The University of Tokyo
  •  Conformation of Contractile Protein in its Transition State as Studied by Phosphorus-31 Nuclear Magnetic ResonancePrincipal Investigator

    • Principal Investigator
      TANOKURA Masaru
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      生物物性学
    • Research Institution
      University of Tokyo
  •  Correlations between the mechanical and biochemical processes of muscle contraction by photogeneration of ATP.

    • Principal Investigator
      YAMADA Kazuhiro
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      大分医科大学
  •  Altered structure of LDL receptor and cholesterol metabolic defects.

    • Principal Investigator
      KUWANO Michihiko
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Medical College of Oita

All 2018 2017 2016 2015 2014 2013 2012 2011 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods (2nd ed.)2015

    • Author(s)
      Takuya Miyakawa, Tingfu Liang, Masaru Tanokura (Debasis Bagchi, Anand Swaroop, Manashi Bagchi, eds.)
    • Total Pages
      9
    • Publisher
      Wiley Blackwell
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Book] Coffee in Health and Disease Prevention.2014

    • Author(s)
      Feifei Wei, Masaru Tanokura
    • Total Pages
      22
    • Publisher
      Academic Press, Elsevier
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Book] 平成24年度低温センター年報2013

    • Author(s)
      魏菲菲, 宮川拓也, 田之倉優
    • Total Pages
      6
    • Publisher
      東京大学低温センター
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Book] 耳鼻咽喉科・頭頚部外科学の最新医療:老人性難聴の予防2005

    • Author(s)
      染谷慎一, 山岨達也, 田之倉優
    • Publisher
      先端医療技術研究社
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] BC-box motif-mediated neuronal differentiation of somatic stem cells2018

    • Author(s)
      Kanno H, Xu Y, Miyakawa T, Kubo A, Higashida T, Kobayashi NB, Yoshida T, Tanokura M
    • Journal Title

      International Journal of Molecular Sci.ence

      Volume: 19 Pages: 466-466

    • DOI

      10.3390/ijms19020466

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10366, KAKENHI-PROJECT-15H05621
  • [Journal Article] Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics.2017

    • Author(s)
      Xu Y, Liu L, Nakamura A, Someya S, Miyakawa T, Tanokura M
    • Journal Title

      Sci Rep. 7(1): 9785

      Volume: 7 Pages: 9785-9785

    • DOI

      10.1038/s41598-017-10337-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05621, KAKENHI-PROJECT-15H04702
  • [Journal Article] G6pd deficiency does not affect the cytosolic glutathione or thioredoxin antioxidant defense in mouse cochlea.2017

    • Author(s)
      White K, Kim MJ, Ding D, Han C, Park HJ, Meneses Z, Tanokura M, Linser P, Salvi R, Someya S.
    • Journal Title

      J Neurosci.

      Volume: 37 Pages: 5770-5781

    • DOI

      10.1523/jneurosci.0519-17.2017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04702
  • [Journal Article] NMR-based analysis of the chemical composition of Japanese persimmon aqueous extracts2016

    • Author(s)
      Shoraku Ryu, Kazuo Furihata, Masanori Koda, Feifei Wei, Takuya Miyakawa, Masaru Tanokura
    • Journal Title

      Magn. Reson. Chem.

      Volume: 54 Pages: 213-221

    • DOI

      10.1002/mrc.4364

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I.2015

    • Author(s)
      Ken-ichi Miyazono, Sonoko Ishino, Kanae Tsutsumi, Tomoko Ito, Yoshizumi Ishino, Masaru Tanokura
    • Journal Title

      Nucleic Acids Res.

      Volume: 43 Pages: 7122-7136

    • DOI

      10.1093/nar/gkv654

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-26242075
  • [Journal Article] Comprehensive NMR analysis of compositional changes of black garlic during thermal processing2015

    • Author(s)
      Tingfu Liang, Feifei Wei, Yi Lu, Yoshinori Kodani, Mitsuhiko Nakada, Takuya Miyakawa, Masaru Tanokura
    • Journal Title

      J. Agric. Food Chem.

      Volume: 63 Pages: 683-691

    • DOI

      10.1021/jf504836d

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Crystal structures of apo-DszC and FMN-bound DszC from Rhodococcus erythropolis D-12015

    • Author(s)
      Li-Jun Guan, Woo Cheol Lee, Shipeng Wang, Takashi Ohshiro, Yoshikazu Izumi, Jun Ohtsuka, Masaru Tanokura
    • Journal Title

      FEBS J.

      Volume: N/A Pages: 3126-3135

    • DOI

      10.1111/febs.13216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] ミトコンドリアと老化2015

    • Author(s)
      宮川拓也、染谷慎一、田之倉優
    • Journal Title

      医学のあゆみ

      Volume: 253 Pages: 733-738

    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein2015

    • Author(s)
      Nishi K, Takahashi T, Suzawa M, Miyakawa T, Nagasawa T, Ming Y, Tanokura M, Ui-Tei K.
    • Journal Title

      Nucleic Acids Res.

      Volume: 43 Pages: 9856-9873

    • DOI

      10.1093/nar/gkv1026

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19124, KAKENHI-PUBLICLY-26102713, KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-15H04319
  • [Journal Article] Structure and reaction mechanism of a novel enone reductase.2015

    • Author(s)
      Feng, H., T. Miyakawa, N. Kitamura, M. Takeuchi, S.B. Park, S. Kishino, J. Ogawa, M. Tanokura
    • Journal Title

      FEBS J.

      Volume: 未定 Pages: 1526-1537

    • DOI

      10.1111/febs.13239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J00686, KAKENHI-PROJECT-23228003
  • [Journal Article] Yam tuber storage protein reduces plant oxidants using the coupled reactions as carbonic anhydrase and dehydroascorbate reductase2015

    • Author(s)
      You-Lin Xue, Takuya Miyakawa, Akira Nakamura, Ken-ichi Hatano, Yoriko Sawano, Masaru Tanokura
    • Journal Title

      Molecular Plant

      Volume: N/A Pages: 1115-1118

    • DOI

      10.1016/j.molp.2015.02.015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-26340069
  • [Journal Article] Electron microscopic recording of myosin head power stroke in hydrated myosin filaments2015

    • Author(s)
      Haruo sugi, Shigeru Chaen, Tsuyoshi Akimoto, Hiroki Minoda, Takuya Miyakawa, Yumiko Miyauchi, Masaru Tanokura, Seiryo Sugiura
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 15700-15700

    • DOI

      10.1038/srep15700

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Structural basis for action of the external chaperone for a propeptide-deficient serine protease from Aeromonas sobria2015

    • Author(s)
      Hidetomo Kobayashi, Toru Yoshida, Takuya Miyakawa, Mitsuru Tashiro, Keinosuke Okamoto, Hiroyasu Yamanaka, Masaru Tanokura and Hideaki Tsuge
    • Journal Title

      J. Biol. Chem.

      Volume: 290(17) Pages: 11130-11143

    • DOI

      10.1074/jbc.m114.622852

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K05550, KAKENHI-PROJECT-23228003
  • [Journal Article] A new target region for changing the substrate specificity of amine transaminases2015

    • Author(s)
      Li-Jun Guan, Jun Ohtsuka, Masahiko Okai, Takuya Miyakawa, Tomoko Mase, Yuehua Zhi, Feng Hou, Noriyuki Ito, Akira Iwasaki, Yoshihiko Yasohara, Masaru Tanokura
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 10753-10753

    • DOI

      10.1038/srep10753

    • NAID

      120006348500

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Splenic stromal cells from aged mice produce higher levels of IL-6 compared to young mice.2014

    • Author(s)
      Jihyun Park, Takuya Miyakawa, Aya Shiokawa, Haruyo Nakajima-Adachi, Masaru Tanokura, Satoshi Hachimura
    • Journal Title

      Mediator. Inflamm.

      Volume: 2014 Pages: 826987-826987

    • DOI

      10.1155/2014/826987

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Calcium-dependent structural changes in human reticulocalbin-1.2014

    • Author(s)
      Nanao Suzuki, Syoko Ban, Eriko Itoh, Sisi chen, Fabiana L. Imai, Yoriko Sawano, Takuya Miyakawa, Masaru Tanokura, Naoto Yonezawa
    • Journal Title

      J. Biochem.

      Volume: N/A

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] A pilot study of NMR-based sensory prediction of roasted coffee bean extracts.2014

    • Author(s)
      Feifei Wei, Kazuo Furihata, Takuya Miyakawa, Masaru Tanokura
    • Journal Title

      Food Chem.

      Volume: 152 Pages: 363-369

    • DOI

      10.1016/j.foodchem.2013.11.161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02090, KAKENHI-PROJECT-23228003
  • [Journal Article] Structural basis of stereospecific reduction by quinuclidinone reductase.2014

    • Author(s)
      Daijiro Takeshita, Michihiko Kataoka, Takuya Miyakawa, Ken-ichi Miyazono, Shoko Kumashiro, Takahiro Nagai, Nobuyuki Urano, Atsuko Uzura, Koji Nagata, Sakayu Shimizu, Masaru Tanokura
    • Journal Title

      AMB Express

      Volume: 4 Pages: 6-6

    • DOI

      10.1186/2191-0855-4-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Attenuation of migration properties of CD4+ T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid and RALDH expression compared to young mice.2014

    • Author(s)
      Jihyun Park, Takuya Miyakawa, Aya Shiokawa, Haruyo Nakajima-Adachi, Masaru Tanokura, Satoshi Hachimura
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 78 Pages: 976-980

    • DOI

      10.1080/09168451.2014.910099

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] A novel mode of ferric ion coordination by the periplasmic ferric ion-binding subunit FbpA of an ABC-type iron transporter from Thermus thermophilus HB8.2014

    • Author(s)
      Shipeng Wang, Misaki Ogata, Shoichiro Horita, Jun Ohtsuka, Koji Nagata, Masaru Tanokura
    • Journal Title

      Acta Crystallogr. D Biol. Crystallogr.

      Volume: 70 Pages: 196-202

    • DOI

      10.1107/s1399004713026333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] A sequence-specific DNA glycosylase mediates restriction-modification in Pyrococcus abysii2014

    • Author(s)
      Ken-ichi Miyazono, Yoshikazu Furuta, Miki Watanabe-Matsui, Takuya Miyakawa, Tomoko Ito, Ichizo Kobayashi, Masaru Tanokura
    • Journal Title

      Nature Communications

      Volume: 5 Pages: 3178-3178

    • DOI

      10.1038/ncomms4178

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PUBLICLY-24113506, KAKENHI-PROJECT-25291080, KAKENHI-PROJECT-25860203, KAKENHI-PROJECT-26650123
  • [Journal Article] Calcium-dependent structural changes in human reticulocalbin-12014

    • Author(s)
      Nanao Suzuki, Shoko Ban, Eriko Itoh, Sisi Chen, Lica Fabiana Imai, Yoriko Sawano, Takuya Miyakawa, Masaru Tanokura, Naoto Yonezawa
    • Journal Title

      Journal of Biochemistry

      Volume: in press

    • DOI

      10.1093/jb/mvu003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570125
  • [Journal Article] Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding.2014

    • Author(s)
      Hui-Min Qin, Akihiro Yamamura, Takuya Miyakawa, Michihiko Kataoka, Takahiro Nagai, Nahoko Kitamura, Nobuyuki Urano, Shintaro Maruoka, Jun Ohtsuka, Koji Nagata, Sakayu Shimizu, Masaru Tanokura
    • Journal Title

      Appl. Microbiol. Biotechnol.

      Volume: 98 Pages: 273-249

    • DOI

      10.1007/s00253-013-5073-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] NMRプロファイリングによる食品の加工・品質・機能性の総合評価.2014

    • Author(s)
      小谷良徳、宮川拓也、田之倉優
    • Journal Title

      BIOINDUSTRY

      Volume: 31 Pages: 15-22

    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Molecular mechanism of strigolactone perception by DWARF14.2013

    • Author(s)
      Hidemitsu Nakamura, Yau-Lin Xue, Takuya Miyakawa, Feng Hou, Hui-Min Qin, Kosuke Fukui, Xuan Shi, Emi Ito, Shinsaku Ito, Seung-Hyun Park, Yumiko Miyauchi, Atsuko Asano, Naoya Totsuka, Takashi Ueda, Masaru Tanakura & Tadao Asami
    • Journal Title

      Nature Comm

      Volume: 4 Pages: 2613-2613

    • DOI

      10.1038/ncomms3613

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-12J04840, KAKENHI-PROJECT-20001009, KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23248018, KAKENHI-PLANNED-24114003, KAKENHI-PROJECT-24370019
  • [Journal Article] Infrared study of synthetic peptide analogues of the calcium-binding site III of troponin C: The role of helix F of an EF-hand motif2013

    • Author(s)
      Masayuki Nara, Hisayuki Morii, Masaru Tanokura
    • Journal Title

      Biopolymers

      Volume: 99 Pages: 342-347

    • DOI

      10.1002/bip.22176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Complex structure of the DNA-binding domain of AdpA, the global transcription factor in Streptomyces griseus, and a target duplex DNA reveals the structural basis of its tolerant DNA sequence specificity.2013

    • Author(s)
      Ming Dong Yao, Jun Ohtsuka, Koji Nagata, Ken-ichi Miyazono, Yuehua Zhi, Yasuo Ohnishi, Masaru Tanokura
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Pages: 31019-31029

    • DOI

      10.1074/jbc.m113.473611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Crystallization and preliminary X-ray analysis of human leukocyte cell-derived chemotaxin 2 (LECT2).2013

    • Author(s)
      Zheng H, Miyakawa T, Sawano Y, Yamagoe S, Tanokura M
    • Journal Title

      Acta Crystallographica Section F

      Volume: 69 Pages: 316-319

    • DOI

      10.1107/s1744309113003758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23590275
  • [Journal Article] Ototoxic model of oxaliplatin and protection from nicotinamide adenine dinucleotide.2013

    • Author(s)
      Dalian Ding, Haiyan Jiang, Yong Fu, Yonggi Li, Richard Salvi, Shinichi Someya, Masaru Tanokura
    • Journal Title

      J. Otol.

      Volume: 8 Pages: 22-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Structural Units Important for Activity of a Novel-type Phosphoserine Phosphatase from Hydrogenobacter thermophilus TK-6 Revealed by Crystal Structure Analysis2013

    • Author(s)
      Yoko Chiba (千葉 洋子)
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Pages: 11448-11458

    • DOI

      10.1074/jbc.m112.449561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J03030, KAKENHI-PROJECT-21248010, KAKENHI-PROJECT-23228003
  • [Journal Article] Expression, high-pressure refolding and purification of human leukocyte cell-derived chemotaxin 2 (LECT2)2013

    • Author(s)
      Hai Zheng, Takuya Miyakawa, Yoriko Sawano, Satoshi Yamagoe, Masaru Tanokura
    • Journal Title

      Protein expression and purification

      Volume: 88 Pages: 221-229

    • DOI

      10.1016/j.pep.2013.01.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23590275
  • [Journal Article] Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD2013

    • Author(s)
      Hui-Min Qin, Takuya Miyakawa, Min Ze Jia, Akira Nakamura, Jun Ohtsuka, You-Lin Xue, Takashi Kawashima, Takuya Kasahara, Makoto Hibi, Jun Ogawa, Masaru Tanokura
    • Journal Title

      PLOS ONE

      Volume: 8

    • DOI

      10.1371/journal.pone.0063996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23248014, KAKENHI-PROJECT-24688010
  • [Journal Article] The flavoenzyme azobenzene reductase AzoR from Escherichia coli binds roseoflavin mononucleotide (RoFMN) with high affinity and is less active in its RoFMN form.2013

    • Author(s)
      Simone Langer, Shinobu Nakanishi, Tilo Mathes, Tanja Knaus, Alexandra Binter, Peter Macheroux, Tomoko Mase, Takuya Miyakawa, Masaru Tanokura, Matthias Mack
    • Journal Title

      Biochemistry

      Volume: 52 Pages: 4288-4295

    • DOI

      10.1021/bi400348d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Evaluation of nonionic adsorption resins for removal of inhibitorycompounds from corncob hydrolysate for ethanol fermentation2013

    • Author(s)
      Ken-ichi Hatano, Naokazu Aoyagi, Takuya Miyakawa, Masaru Tanokura, Kenji Kubota
    • Journal Title

      Bioresurce Technology

      Volume: 149 Pages: 541-545

    • DOI

      10.1016/j.biortech.2013.08.166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-24550245
  • [Journal Article] Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: A single amino acid substitution reverses their cyclization specificity.2013

    • Author(s)
      Ryutaro Satou, Akimasa Miyanaga, Hiroki Ozawa, Nobutaka Funa, Yohei Katsuyama, Ken-ichi Miyazono, Masaru Tanokura, Yasuo Ohnishi, Sueharu Horinouchi
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Pages: 34146-34157

    • DOI

      10.1074/jbc.m113.487272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Structure and function of abscisic acid receptors2013

    • Author(s)
      Takuya Miyakawa, Yasunari Fujita, Kazuko Yamaguchi-Shinozaki, Masaru Tanokura
    • Journal Title

      Trends Plant Sci

      Volume: 18 Pages: 259-266

    • DOI

      10.1016/j.tplants.2012.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23770104
  • [Journal Article] ミトコンドリアと老化2013

    • Author(s)
      染谷慎一, 田之倉優
    • Journal Title

      実験医学 増刊

      Volume: 31 Pages: 141-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Development of a peptide antagonist against fsr quorum sensing of Enterococcus faecalis2013

    • Author(s)
      Jiro Nakayama, Ryoji Yokohata, Mami Sato, Takashi Suzuki, Takahisa Matsufuji, Kenzo Nishiguchi, Takeshi Kawai, Yosuke Yamanaka, Koji Nagata, Masaru Tanokura, Kenji Sonomoto
    • Journal Title

      ACS Chem Biol

      Volume: 8 Pages: 804-811

    • DOI

      10.1021/cb300717f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-24380050
  • [Journal Article] Coordination to divalent cations by calcium-binding proteins studied by FTIR spectroscopy.2013

    • Author(s)
      Masayuki Nara, Hisayuki Morii, Masaru Tanokura
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1828 Pages: 2319-2327

    • DOI

      10.1016/j.bbamem.2012.11.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Crystal structure and site-directed mutagenesis analysis of haloalkane dehalogenase LinB from Sphingobium sp. MI12052013

    • Author(s)
      Masahiko Okai, Jun Ohtsuka, Fabiana L. Imai, Tomoko Mase, Ryota Moriuchi, Masataka Tsuda, Koji Nagata, Yuji Nagata, Masaru Tanokura
    • Journal Title

      J. Bacteriol.

      Volume: 195 Pages: 2642-2651

    • DOI

      10.1128/jb.02020-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-24658068, KAKENHI-PROJECT-25292043
  • [Journal Article] Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA.2013

    • Author(s)
      Takahashi T, Miyakawa T, Zenno S, Nishi K, Tanokura M, Ui-Tei
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0063434

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23228003
  • [Journal Article] A thermoacidophile-specific protein family, DUF3211, functions as a fatty acid carrier with novel binding mode.2013

    • Author(s)
      Takuya Miyakawa, Yoriko Sawano, Ken-ichi Miyazono, Yumiko Miyauchi, Ken-ichi Hatano, Masaru Tanokura
    • Journal Title

      J. Bacteriol.

      Volume: 195 Pages: 4005-4012

    • DOI

      10.1128/jb.00432-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] The effect of acyclic retinoid on the metabolomic profiles of hepatocytes and hepatocellular carcinoma cells.2013

    • Author(s)
      Xian-Yang Qin, Feifei Wei, Masaru Tanokura, Naoto Ishibashi, Masahito Shimizu, Hisataka Moriwaki, Soichi Kojima
    • Journal Title

      PloS one

      Volume: 8

    • DOI

      10.1371/journal.pone.0082860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02090, KAKENHI-PROJECT-13F03217, KAKENHI-PROJECT-23228003, KAKENHI-PUBLICLY-24102533, KAKENHI-PROJECT-25460987, KAKENHI-PROJECT-25460988, KAKENHI-PROJECT-221S0001
  • [Journal Article] Crystal structure of conjugated polyketone reductase (CPR-C1) from Candida parapsilosis IFO 0708 complexed with NADPH.2013

    • Author(s)
      Hui-Min Qin, Akihiro Yamamura, Takuya Miyakawa, Michihiko Kataoka, Shintaro Maruoka, Jun Ohtsuka, Koji Nagata, Sakayu Shimizu, Masaru Tanokura
    • Journal Title

      Proteins

      Volume: 81 Pages: 2059-2063

    • DOI

      10.1002/prot.24363

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein.2013

    • Author(s)
      Okumura A, Suzuki T, Miyatake H, Okabe T, Hashimoto Y, Miyakawa T, Zheng H, Unoki-Kubota H, Ohno H, Dohmae N, Kaburagi Y, Miyazaki Y, Tanokura M, Yamagoe S
    • Journal Title

      FEBS Letters

      Volume: 587 Pages: 404-409

    • DOI

      10.1016/j.febslet.2013.01.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23500870, KAKENHI-PROJECT-23590275, KAKENHI-PROJECT-24790938, KAKENHI-PROJECT-25461370
  • [Journal Article] Addition of exogenous NAD+ prevents mefloquine-induced neuroaxonal and hair cell degeneration through reduction of caspase-3-mediated apoptosis in cochlear organotypic cultures.2013

    • Author(s)
      Dalian Ding, Weidong Qi, Dongzhen Yu, Haiyan Jiang, Chul Han, Mi-Jung Kim, Kana Katsuno, Yun Hua Hsieh, Takuya Miyakawa, Richard Salvi, Masaru Tanokura, Shinichi Someya
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0079817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Structure of the Ca2+-saturated C-terminal domain of scallop troponin C in complex with a troponin I fragment.2013

    • Author(s)
      Kato YS, Yumoto F, Tanaka H, Miyakawa T, Miyauchi Y, Takeshita D, Sawano Y, Ojima T, Ohtsuki I, Tanokura M
    • Journal Title

      Biol Chem.

      Volume: 394 Pages: 55-68

    • DOI

      10.1515/hsz-2012-0152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-24659268
  • [Journal Article] Experimental evidence for the thermophilicity of ancestral life2013

    • Author(s)
      Satoshi Akanuma, Yoshiki Nakajima, Shin-ichi Yokobori, Mitsuo Kimura, Naoki Nemoto, Tomoko Mase, Ken-ichi Miyazono, Masaru Tanokura, Akihiko Yamagishi
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 110 Pages: 11067-11072

    • DOI

      10.1073/pnas.1308215110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23370097, KAKENHI-PROJECT-24560966
  • [Journal Article] Coordination structures of Mg2+ and Ca2+ in three types of tobacco calmodulins in solution: Fourier-transform infrared spectroscopic studies of side-chain COO- groups.2013

    • Author(s)
      N. Suzuki, L. F. Imai, Y. Kato, K. Nagata, Y. Ohashi, K. Kuchitsu, M. Tanokura, A. Sakamoto, M. Nara, M. Nakano, and N. Yonezawa
    • Journal Title

      Biopolymers.

      Volume: 99 Pages: 472-483

    • DOI

      10.1002/bip.22203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22550005, KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23380027, KAKENHI-PROJECT-23658061, KAKENHI-PROJECT-24570125, KAKENHI-PROJECT-24659268, KAKENHI-PUBLICLY-25114515, KAKENHI-PROJECT-25660049, KAKENHI-PUBLICLY-23117718
  • [Journal Article] Substrate recognition mechanism and substrate-dependent conformational changes of an ROK family glucokinase from Streptomyces griseus2012

    • Author(s)
      K.Miyazono, N.Tabei, 他3名, M.Tanokura
    • Journal Title

      J Bacteriol

      Volume: 194 Pages: 607-616

    • DOI

      10.1128/jb.06173-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Cloning of genes and enzymatic characterizations of novel dioscorin isoforms from Dioscorea japonica2012

    • Author(s)
      YL.Xue, T.Miyakawa, Y.Sawano, M.Tanokura
    • Journal Title

      Plant Sci

      Volume: 183 Pages: 14-19

    • DOI

      10.1016/j.plantsci.2011.10.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Roasting process of coffee beans as studied by nuclear magnetic resonance : time course of changes in composition2012

    • Author(s)
      F.Wei, K.Furihata, M.Koda, F.Hu, T.Miyakawa, M.Tanokura
    • Journal Title

      J Agric Food Chem

      Volume: 60 Pages: 1005-1012

    • DOI

      10.1021/jf205315r

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Calaxin drives sperm chemotaxis by Ca2+-mediated direct modulation of a dynein motor.2012

    • Author(s)
      Mizuno K, Shiba K, Okai M, Takahashi Y, Shitaka Y, Oiwa K, Tanokura M, Inaba K.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 109 Pages: 20497-20502

    • DOI

      10.1073/pnas.1217018109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21112004, KAKENHI-PROJECT-22370023, KAKENHI-PROJECT-23228003
  • [Journal Article] High pressure refolding, purification, and crystallization of flavin reductase from Sulfolobus tokodaii strain 72012

    • Author(s)
      Okai M, Ohtsuka J, Asano A, Guo L, Miyakawa T, Miyazono K, Nakamura A, Okada A, Zheng H, Kimura K, Nagata K, Tanokura M
    • Journal Title

      Protein Expr Purif

      Volume: 84 Pages: 214-218

    • DOI

      10.1016/j.pep.2012.06.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Effect of low-dose thalidomide on dopaminergic neuronal differentiation of human neural progenitor cells: A combined study of metabolomics and morphological analysis.2012

    • Author(s)
      Qin XY, Akanuma H, Wei F, Nagano R, Zeng Q, Imanishi S, Ohsako S, Yoshinaga J, Yonemoto J, Tanokura M, Sone H
    • Journal Title

      Neurotoxicology

      Volume: 33 Pages: 1375-1380

    • DOI

      10.1016/j.neuro.2012.08.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-23310044, KAKENHI-PROJECT-23658237
  • [Journal Article] Metabolic discrimination of mango juice from various cultivars by band-selective NMR spectroscopy2012

    • Author(s)
      M.Koda, K.Furihata, F.Wei, T.Miyakawa, M.Tanokura
    • Journal Title

      J Agric Food Chem

      Volume: 60 Pages: 1158-1166

    • DOI

      10.1021/jf2041438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] The crystal structure of an intermediate dimer of aspergilloglutamic peptidase that mimics the enzyme-activation product complex produced upon autoproteolysis.2012

    • Author(s)
      Sasaki H, Kubota K, Lee WC, Ohtsuka J, Kojima M, Iwata S, Nakagawa A, Takahashi K, Tanokura M
    • Journal Title

      The Journal of Biochemistry

      Volume: 152 Pages: 45-52

    • DOI

      10.1093/jb/mvs050

    • NAID

      10031166113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003, KAKENHI-PROJECT-24770089
  • [Journal Article] Crystallization and preliminary X-ray crystallographic analysis of dioscorin from Dioscorea japonica2012

    • Author(s)
      YL.Xue, T.Miyakawa, Y.Sawano, M.Tanokura
    • Journal Title

      Ada Crystallogr Sect F Struct Biol Cryst Commun

      Volume: 68 Pages: 193-195

    • DOI

      10.1107/s1744309111053723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] NMR-based metabolic profiling of rice wines by F(2)-selective total correlation spectra2012

    • Author(s)
      Koda M, Furihata K, Wei F, Miyakawa T, Tanokura M
    • Journal Title

      J Agric Food Chem

      Volume: 60 Pages: 4818-4825

    • DOI

      10.1021/jf3008647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Different Ca(2+)-sensitivities between the EF-hands of T- and L-plastins2012

    • Author(s)
      Miyakawa T, Shinomiya H, Yumoto F, Miyauchi Y, Tanaka H, Ojima T, Kato YS, Tanokura M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 429 Pages: 137-141

    • DOI

      10.1016/j.bbrc.2012.10.126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Two-dimensional 1H-13C nuclear magnetic resonance (NMR)-based comprehensive analysis of roasted coffee bean extract2011

    • Author(s)
      F.Wei, K.Furihata, F.Hu, T.Miyakawa, M.Tanokura
    • Journal Title

      J Agric Food Chem

      Volume: 59 Pages: 9065-9073

    • DOI

      10.1021/jf201716w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Solution structure of a short-chain insecticidal toxin LaIT1 from the venom of scorpion Liocheles australasiae2011

    • Author(s)
      S.Horita, N.Matsushita, 他7名, M.Tanokura
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 411 Pages: 738-744

    • DOI

      10.1016/j.bbrc.2011.07.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Journal Article] Up-to-date of medicine for otolaryngology and head and neck surgery.2005

    • Author(s)
      Someya S, Yamasoba T, Tanokura M
    • Journal Title

      Prevention of presbycusis. (Kaga K & Komune S (Eds).)(Sentan-iryogijutsu-kenkyusyo, Tokyo)(in Japanese)

      Pages: 110-113

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] 老人性難聴の予防.2005

    • Author(s)
      染谷慎一, 山岨達也, 田之倉優
    • Journal Title

      耳鼻咽喉科・頭頚部外科学の最新医療(加我君孝・小宗静男編)

      Pages: 110-113

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging.2005

    • Author(s)
      Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth S, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C, Prolla TA
    • Journal Title

      Science 309

      Pages: 481-484

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Purification and gene cloning of Fundulus heteroclitus hatching enzyme : A hatching enzyme system composed of high choriolytic enzyme (HCE) and low choriolytic enzyme (LCE) is conserved between two different teleosts, F. heteroclitus and medaka Oryzias latipes.2005

    • Author(s)
      Kawaguchi M., Yasumasu S., Shimizu S., Hiroi J., Yoshizak N., Nagata K., Tanokura M, Iuchi I.
    • Journal Title

      Eur.J.Biochem.

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570102
  • [Journal Article] Purification and gene cloning of Fundulus heteroclitus hatching enzyme : A hatching enzyme system composed of high choriolytic enzyme (HCE) and low choriolytic enzyme (LCE) is conserved between two different teleosts, F.heteroclitus and medaka Oryzias Latipes.2005

    • Author(s)
      Kawaguchi M., Yasumasu S., Shimizu S., Hiroi J., Yoshizaki N., Nagata K., Tanokura M., Iuchi I.
    • Journal Title

      FEBES J. 272

      Pages: 4315-4326

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570102
  • [Journal Article] Mitochondrial DNA mutations, oxidative stress and apoptosis in mammalian aging.2005

    • Author(s)
      Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth S, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C, Prolla TA.
    • Journal Title

      Science 309

      Pages: 481-484

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Crystallization and preliminary X-ray analyses of desulfurization enzyme DszB and its C27S mutant complexed with biphenyl-2-sulfinic acid2004

    • Author(s)
      W.C.Lee, T.Ohshiro, T.Matsubara, Y.Izumi, M.Tanokura
    • Journal Title

      Acta.Crystallogr D 60

      Pages: 1636-1638

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15580063
  • [Journal Article] Crystallization and preliminary X-ray analysis of HCE-1, a hatching enzyme of medaka fish, Oryzias latipes.2004

    • Author(s)
      Kudo, N., Yasumasu, S., Iuchi, I., Tanokura, M.
    • Journal Title

      Acta Cryst. D60

      Pages: 725-726

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570102
  • [Journal Article] Cloning, purification, crystallization and preliminary crystallographic analysis of acylphosphatase from Pyrococcus horikoshii.2004

    • Author(s)
      Miyazono K, Kudo N, Tanokura M
    • Journal Title

      Acta Crystal 60

      Pages: 1135-1136

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Purification and characterization of an aminopeptidase from Lactobacillus helveticus JCM 1004.2004

    • Author(s)
      Pan D, Tanokura M
    • Journal Title

      Food Chem 88

      Pages: 511-516

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Crystallization and preliminary X-ray analysis of HCE-1, a hatching enzyme of medaka fish, Oryzias latipes.2004

    • Author(s)
      Kudo, N., Yasumasu S., Iuchi, I., Tanokura, M.
    • Journal Title

      Acta Cryst. D60

      Pages: 725-726

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570102
  • [Journal Article] Crystallization and preliminary X-ray analyses of desulfurization enzyme DszB and its C27S mutant complexed with biphenyl-2-sulfinic acid2004

    • Author(s)
      W.C.Lee, T.Ohshiro, T.Matsubara, Y.Izumi, M.Tanokura
    • Journal Title

      Acta.Cryst.allogr D60

      Pages: 1-3

    • Data Source
      KAKENHI-PROJECT-15580063
  • [Journal Article] Crystallization and preliminary X-ray analyses of desulfurization enzyme DszB and its C27S mutant complexed with biphenyl-2-sulfinic acid2004

    • Author(s)
      W.C.Lee, T.Ohshiro, T.Matsubara, Y.Izumi, M.Tanokura
    • Journal Title

      Acta.Crystallogr D60

      Pages: 1636-1638

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15580063
  • [Journal Article] Backbone ^1H, ^<13>C, and ^<15>N resonance assignment of the N-terminal domain of human eRF12004

    • Author(s)
      Oda Y, Muramatsu T, Yumoto F, Ito M, Tanokura M
    • Journal Title

      J Biomol NMR 30

      Pages: 109-110

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Crystal structure of the terminal oxygenase component of biphenyl dioxygenase derived from Rhodococcus sp. strain.2004

    • Author(s)
      Furusawa Y, Nagarajan V, Tanokura M et al.
    • Journal Title

      J Mol Biol 342

      Pages: 1041-1052

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss.

    • Author(s)
      Yamasoba T, Someya S, Yamada C, Weindruch R, Prolla TA, Tanokura M
    • Journal Title

      Hearing Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ.

    • Author(s)
      Someya S, Yamasoba T, Kujoth GC, Pugh TD, Weindruch R, Tanokura M, Prolla TA
    • Journal Title

      Neurobiology of Aging (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis.

    • Author(s)
      Someya S, Yamasoba T, Weindruch R, Prolla TA, Tanokura M
    • Journal Title

      Neurobiology of Aging (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ.

    • Author(s)
      Someya S, Yamasoba T, Kujoth GC, Pugh TD, Weindruch R, Tanokura M, Prolla TA
    • Journal Title

      Neurobiology of Aging (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis.

    • Author(s)
      Someya S, Yamasoba T, Weindruch R, Prolla TA, Tanokura M
    • Journal Title

      Neurobiology of Aging (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss.

    • Author(s)
      Yamasoba T, Someya S, Yamada C, Weindruch R, Prolla TA, Tanokura M
    • Journal Title

      Hearing Research (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] The role of mtDNA mutations in the pathogenesis of age-related hearing loss in nmice carrying a mutator DNA polymerase γ.

    • Author(s)
      Someya S, Yamasoba T, Kujoth GC, Pugh TD, Weindruch R, Tanokura M, Prolla TA
    • Journal Title

      Neurobiology of Aging (in press)

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis.

    • Author(s)
      Someya S, Yamasoba T, Weindruch R, Prolla TA, Tanokura M
    • Journal Title

      Neurobiology of Aging (in press)

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Journal Article] Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss.

    • Author(s)
      Yamasoba T, Someya S, Yamada C, Weindruch R, Prolla TA, Tanokura M
    • Journal Title

      Hearing Research (in press)

    • Data Source
      KAKENHI-PROJECT-16390486
  • [Presentation] 皮膚由来間葉系幹細胞を用いた脳梗塞/認知症に対する神経再生医療の研究2017

    • Author(s)
      菅野 洋, 篠永正道,永山正雄, 宮川拓也, 田之倉優
    • Organizer
      第16回日本再生医療学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-07
    • Data Source
      KAKENHI-PROJECT-15K10366
  • [Presentation] 幹細胞を用いた脳梗塞/認知症に対する再生医療の研究..国際医療福祉大学、大田原、2017.8.27 .2017

    • Author(s)
      菅野 洋, 永山正雄, 宮川拓也, 田之倉 優
    • Organizer
      第7回国際医療福祉大学学術大会
    • Data Source
      KAKENHI-PROJECT-15K10366
  • [Presentation] 分子栄養.Productive Aging-分子生物学・食品科学・生物物理化学を基盤とした医食同源の実現を目指して2016

    • Author(s)
      田之倉 優
    • Organizer
      JST-CRDS ライフサイエンス・臨床医学分野ワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2016-04-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04702
  • [Presentation] Structural biology of phytohormone receptors for plant regulation2016

    • Author(s)
      Masaru Tanokura
    • Organizer
      RCAST-AICT Joint Workshop 「Research Activity Today ~Thinking of Industry-Acdemia-Government Collaboration and Social Contribution~」
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2016-01-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] M23メタロペプチダーゼフォールドをもつヘパトカインLECT2の機能進化の構造基盤2016

    • Author(s)
      宮川拓也、鄭海、澤野頼子、山越智、田之倉優
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 腸間膜リンパ節樹状細胞のRALDH活性および腸管指向性ホーミングレセプター誘導能の加齢による変化2016

    • Author(s)
      高野智弘、上滝隆太郎、宮川拓也、朴知賢、塩河亜弥、好田正、足立(中嶋)はるよ、田之倉優、八村 敏志
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 体性幹細胞を用いた脳梗塞/認知症に対する神経再生医療の研究2016

    • Author(s)
      菅野 洋, 篠永正道, 永山正雄, 徐 玉群, 宮川拓也, 田之倉優
    • Organizer
      第75回日本脳神経外科学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-28
    • Data Source
      KAKENHI-PROJECT-15K10366
  • [Presentation] Productive Agingと食-分子生物学・食品科学・生物物理化学を基盤とした医食同源の実現を目指して-2016

    • Author(s)
      田之倉優
    • Organizer
      第2回Geroscience Initiative Japan
    • Place of Presentation
      グランフロント大阪 ナレッジキャピタル コングレコンベンションセンター(大阪)
    • Year and Date
      2016-03-12
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] NMR-based metabolomics in foods2015

    • Author(s)
      Masaru Tanokura
    • Organizer
      Seminar in Liaoning University
    • Place of Presentation
      Shenyang, China
    • Year and Date
      2015-06-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Age-related hearing loss (AHL): Molecular mechanism and suppression2015

    • Author(s)
      Masaru Tanokura
    • Organizer
      Lithuania-Japan Joint Life Science Symposium
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2015-10-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] A sequence-specific DNA glycosylase mediates restriction-modification in Pyrococcus abyssi2015

    • Author(s)
      Kenichi Miyakazono, Yoshikazu Furuta, Miki Watanabe-Matui, Takuya Miyakawa, Tomoko Ito, Ichizo Kobayashi, Masaru Tanokura
    • Organizer
      The 29th European Crystallographic Meeting
    • Place of Presentation
      Rovinj, Croatia
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] NMR-based metabolomics of elm skins as classical seasonings2015

    • Author(s)
      Anh Hong Phan, Ei-ichiro Suzuki, Yoshinori Kodani, Takuya Miyakawa, Masaru Tanokura
    • Organizer
      第54回NMR討論会
    • Place of Presentation
      千葉工業大学(千葉)
    • Year and Date
      2015-11-06
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 加齢性炎症と食品による抑制2015

    • Author(s)
      八村敏志、宮川拓也、片倉喜範、田之倉優
    • Organizer
      日本食品免疫学会2015年度大会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2015-10-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 制限DNAグリコシラーゼR.PabIによる認識配列探索機構2015

    • Author(s)
      王徳龍、宮園健一、田之倉優
    • Organizer
      日本結晶学会平成27年度年会
    • Place of Presentation
      大阪府立大学(大阪)
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 文献情報に基づいた老化関連遺伝子研究の潮流:過去・現在・未来2015

    • Author(s)
      權娟大、永田宏次、宮川拓也、由良敬、田之倉優
    • Organizer
      BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Structural biology of enzymes for industrial usage2015

    • Author(s)
      Masaru Tanokura
    • Organizer
      Seminar in Tianjin Universtiyr of Science and Technology
    • Place of Presentation
      Tianjin, China
    • Year and Date
      2015-09-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 腸間膜リンパ節樹状細胞におけるRALDH2発現のサブセット間比較および加齢による影響2015

    • Author(s)
      高野智弘、上滝隆太郎、宮川拓也、好田正、牧野聖也、狩野宏、足立(中嶋)はるよ、田之倉優、八村敏志
    • Organizer
      日本食品免疫学会2015年度大会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2015-10-15
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] NMR-based metabolomics of foods2015

    • Author(s)
      Masaru Tanokura
    • Organizer
      The 6th International Conference on Food Factors - ICoFF 2015
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-12-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] NMRを用いた食品成分による黒ニンニクの熟成過程の解析.2015

    • Author(s)
      梁庭輔、小谷良徳、魏菲菲、盧翌、中田光彦、宮川拓也、田之倉優
    • Organizer
      日本農芸化学会2015年度大会
    • Place of Presentation
      岡山大学(岡山)
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] グリオーマ幹細胞における幹細胞マーカーの転写制御機構2015

    • Author(s)
      菅野 洋, 篠永正道, 宮川拓也, 田之倉優
    • Organizer
      第33回日本脳腫瘍学会
    • Place of Presentation
      京都グランドプリンスホテル(京都府、京都市)
    • Year and Date
      2015-12-06
    • Data Source
      KAKENHI-PROJECT-15K10366
  • [Presentation] Aeromonas sobria由来プロペプチド欠損セリンプロテアーゼの外部シャペロンによるフォールディング機構2015

    • Author(s)
      吉田徹、小林秀丈、宮川拓也、田代充、岡本敬の介、山中浩泰、田之倉優、津下英明
    • Organizer
      BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 幹細胞分化の制御を担う転写因子複合体の構造機能解析2015

    • Author(s)
      宮園健一、栗崎晃、浅島誠、田之倉優
    • Organizer
      日本結晶学会平成27年度年会
    • Place of Presentation
      大阪府立大学(大阪)
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 哺乳類細胞における、アポトーシス誘導によるRNAサイレンシング調節因子TRBPの機能変換2015

    • Author(s)
      高橋朋子、宮川拓也、善野修平、田之倉優、程久美子
    • Organizer
      BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 腸間膜リンパ節樹状細胞におけるRALDH2発現の低下と乳酸菌による調節.2014

    • Author(s)
      高野智弘、宮川拓也、上滝隆太郎、牧野聖也、狩野宏、浅見幸夫、足立(中嶋)はるよ、田之倉優、八村敏志
    • Organizer
      日本食品免疫学会2014年度大会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] NMRプロファイリングによる食品の加工・品質・機能性の総合評価.2014

    • Author(s)
      田之倉優
    • Organizer
      よこはまNMR研究会第51回ワークショップ「メタボロミクス」
    • Place of Presentation
      横浜市立大学(神奈川)
    • Year and Date
      2014-12-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] ヒトReticulocalbin-1のカルシウム依存的構造変化2014

    • Author(s)
      鈴木 七緒、陳 思思、今井 ファビアナ リカ、澤野 頼子、宮川 拓也、田之倉 優、米澤 直人
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      横浜産貿易ホール マリネリア
    • Year and Date
      2014-06-26
    • Data Source
      KAKENHI-PROJECT-24570125
  • [Presentation] コーヒーのNMRプロファイリングと官能評価への応用2014

    • Author(s)
      宮川拓也、魏菲菲、田之倉優
    • Organizer
      平成25年度低温センター研究交流会
    • Place of Presentation
      東京大学(東京)
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 加齢による免疫機能変化と食品による調節2014

    • Author(s)
      八村敏志、田之倉優
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      明治大学(神奈川)
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Crystal structure of human leukocyte cell-derived chemotaxin 2 (LECT2)2013

    • Author(s)
      Hai Zheng, Takuya Miyakawa, Yoriko Sawano, Satoshi Yamagoe, Masaru Tanokura
    • Organizer
      The 12th Conference of the Asian Crystallographic Association
    • Place of Presentation
      香港
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Comprehensive analysis of coffee bean extracts by NMR spectroscopy2012

    • Author(s)
      Wei F, Furihata K, Miyakawa T, Koda M, Hu F, Tanokura M
    • Organizer
      The 53rd Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      Miami, Florida, USA
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] カロリー制限による加齢性難聴の抑制はSirt3が媒介する2012

    • Author(s)
      染谷慎一、田之倉優
    • Organizer
      第28回臨床フリーラジカル会議
    • Place of Presentation
      烟河(京都)(招待講演)
    • Year and Date
      2012-01-20
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] ヒトReticulocalbin-1のカルシウム依存的構造変化2012

    • Author(s)
      鈴木七緒、陳思思、坂象子、今井ファビアナリカ、永田宏次、田之倉優、中野實、米澤直人
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-24570125
  • [Presentation] Structure based mechanism of a novel enone reductase CLA-ER.

    • Author(s)
      Takuya Miyakawa, Feng Hou, Shigenobu Kishino, Jun Ogawa, Masaru Tanokura
    • Organizer
      18th International Symposium on Flavins and Flavoproteins
    • Place of Presentation
      Phechaburi, Thailand
    • Year and Date
      2014-07-27 – 2014-08-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] The composition changes of black garlic during thermal process as studied by nuclear magnetic resonance.

    • Author(s)
      Ting-Fu Liang, Feifei Wei, Takuya Miyakawa, Masaru Tanokura
    • Organizer
      FoodMR 2014
    • Place of Presentation
      Cesena, Italy
    • Year and Date
      2014-05-20 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Comprehensive analysis of coffee bean extracts by NMR spectroscopy

    • Author(s)
      Wei F, Furihata K, Hu F, Miyakawa T, Koda M, Tanokura M
    • Organizer
      11th International Conference on the Application of Magnetic Resonance in Food
    • Place of Presentation
      Wageningen, Netherlands
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] ヤム塊茎貯蔵タンパク質dioscorinにおける炭酸脱水-デヒドロアスコルビン酸還元の共役反応を可能にする構造基盤.

    • Author(s)
      宮川拓也、薛友林、中村顕、秦野賢一、澤野頼子、田之倉優
    • Organizer
      平成26年度日本結晶学会年会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2014-11-01 – 2014-11-03
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] 食品中の微量成分の同定および定量のためのBroad Band WET法

    • Author(s)
      張 晶, 降旗 一夫, 甲田 政則, 魏 菲菲, 宮川 拓也, 田之倉 優
    • Organizer
      日本農芸化学会2013年度大会
    • Place of Presentation
      東北大学(宮城)
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Recent study in structural biology.

    • Author(s)
      Masaru Tanokura
    • Organizer
      Summer School of Zhengzhou University-the forum of Structural biology
    • Place of Presentation
      Zhengzhou, China
    • Year and Date
      2014-07-15 – 2014-07-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Calcium-dependent structural changes in human reticulocalbin-1

    • Author(s)
      Nanao Suzuki, Syoko Ban, Eriko Itoh, Sisi Chen, Fabiana L. Imai, Yoriko Sawano, Masaru Tanokura, Naoto Yonezawa
    • Organizer
      The 27th Annual Symposium of the Protein Society
    • Place of Presentation
      Boston Marriott Copley Place, USA
    • Data Source
      KAKENHI-PROJECT-24570125
  • [Presentation] Crystal structures of apo and FMN-bound DszC from Rhodococcus erythropolis: FMN-dependent monooxygenase for the first step in desulfurization.

    • Author(s)
      Lijun Guan, Shipeng Wang, Woo Cheol Lee, Takashi Ohshiro, Yoshikazu Izumi, Jun Ohtsuka, Masaru Tanokura
    • Organizer
      18th International Symposium on Flavins and Flavoproteins
    • Place of Presentation
      Phechaburi, Thailand
    • Year and Date
      2014-07-27 – 2014-08-01
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] ヤム塊茎貯蔵タンパク質dioscorinの炭酸脱水-デヒドロアスコルビン酸還元共役反応の解析.

    • Author(s)
      宮川拓也、薛友林、中村顕、秦野賢一、澤野頼子、田之倉優
    • Organizer
      日本バイオイメージング学会 第23回学術集会
    • Place of Presentation
      大阪大学(大阪)
    • Year and Date
      2014-09-04 – 2014-09-06
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Flavin binding preference of flavin reductase HpaC from Sulfolobus tokodaii strain 7.

    • Author(s)
      Masahiko Okai, Yuqun Xu, Keita Kuroki, Jun Ohtsuka, Takuya Miyakawa, Masaru Tanokura
    • Organizer
      18th International Symposium on Flavins and Flavoproteins
    • Place of Presentation
      Phechaburi, Thailand
    • Year and Date
      2014-07-27 – 2014-08-01
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] ヒトReticulocalbin-1のカルシウム依存的構造変化

    • Author(s)
      鈴木七緒,陳思思,宮川拓也,永田宏次,田之倉優,中野實,米澤直人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24570125
  • [Presentation] A pilot study of NMR-based sensory prediction of roasted coffee bean extracts.

    • Author(s)
      Takuya Miyakawa, Feifei Wei, Masaru Tanokura
    • Organizer
      FoodMR 2014
    • Place of Presentation
      Cesena, Italy
    • Year and Date
      2014-05-20 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] NMRによるヨーグルトの非破壊分析

    • Author(s)
      盧 翌, 魏 菲菲, 降旗 一夫, 宮川 拓也, 田之倉 優
    • Organizer
      日本農芸化学会2013年度大会
    • Place of Presentation
      東北大学(宮城)
    • Data Source
      KAKENHI-PROJECT-23228003
  • [Presentation] Coordination structures of Mg(2+) and Ca(2+) in three types of tobacco calmodulins in solution: Fourier-transform infrared spectroscopic studies of side-chain COO- groups

    • Author(s)
      Nanao Suzuki, Lica Fabiana Imai, Yusuke Kato, Koji Nagata, Yuko Ohashi, Kazuyuki Kuchitsu, Masaru Tanokura, Akira Sakamoto, Masayuki Nara, Minoru Nakano, Naoto Yonezawa
    • Organizer
      7th International Conference on Advanced Vibrational Spectroscopy
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-24570125
  • 1.  TAKAHASHI Kenji (70011533)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  MITSUI Yukio (40012637)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  MURAMATSU Tomonari (70212256)
    # of Collaborated Projects: 3 results
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  • 4.  SASAKI Hiroshi (80272467)
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  • 5.  YONEZAWA Naoto (80212314)
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    # of Collaborated Products: 7 results
  • 6.  YANAGIDA Mitsuaki (80365569)
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  • 7.  MIYAKAWA Takuya (50596559)
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  • 12.  TAKAHASHI Takayuki (80197152)
    # of Collaborated Projects: 1 results
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  • 13.  SAKABE Noriyoshi (30022601)
    # of Collaborated Projects: 1 results
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  • 14.  YAMANE Takashi (80030055)
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  • 15.  NISHIYAMA Makoto (00208240)
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  • 19.  MIKI Kunio (10116105)
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  • 20.  ISHIKAWA Hiromichi (20051667)
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  • 21.  SUEMATSU Makoto (00206385)
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  • 22.  KOYASU Shigeo (90153684)
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  • 23.  OHTEKI Toshiaki (50233200)
    # of Collaborated Projects: 1 results
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  • 24.  WATANABE Mamoru (10175127)
    # of Collaborated Projects: 1 results
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  • 25.  YASUMASU Shigeki (00222357)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 26.  IUCHI Ichiro (10011694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 27.  IZUMI Yoshikazu (40026555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 28.  OHSHIRO Takashi (00233106)
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  • 29.  FURIHATA Kazuo (20219091)
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  • 30.  OKUBO Akira (20111479)
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  • 31.  YAMASOBA Tatsuya (60251302)
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  • 99.  森 満
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  • 110.  山岸 明彦
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  • 111.  坂本 章
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  • 112.  朽津 和幸
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  • 113.  鈴木 和男
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