Tada Shusuke 多田周右

… Alternative Names

TADA Shusuke 多田周右

多田周右タダシュウスケ

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Researcher Number	00216970
Affiliation (Current)	2023: 東邦大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2017: 東邦大学, 薬学部, 教授 2010 – 2013: 帝京平成大学, 薬学部, 教授 2007 – 2009: Tohoku University, 大学院・薬学研究科, 助教 2006: Tohoku University, Graduate School of Pharmaceutical Sciences, Research associate., 大学院薬学研究科, 助手 2002 – 2005: 東北大学, 大学院・薬学研究科, 助手 1994 – 1995: 東京大学, 薬学部, 助手 1992: 東京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / Functional biochemistry Except Principal Investigator Biological pharmacy / 代謝生物化学 / Biological pharmacy
Keywords	Principal Investigator DNA複製 / RecQL4 / DNA修復 / Cdt1 / Xenopus卵抽出液無細胞実験系 / Rothmund-Thomson症候群 / 非相同末端結合修復 / DNA二本鎖切断 / Cdc6 / DNA組換え修復 … More / geminin / RecQヘリカーゼ / ゲノム安定性維持 / BLM / DNAヘリカーゼ / 細胞周期チェックポイント / RecQファミリーDNAヘリカーゼ / checkpoint機構 / 遺伝情報安定性維持機構 / DNA二本鎖切断修復 / non-homologous end-joining / Xenopus egg extract cell-free system / WRN / 温度感受性変異株 / DNAプライマーゼ / がん / DNA複製タンパク質A / Rad51 / Dpb11 / Sgs1 / ロスムンド・トムソン症候群 / 紫外線感受性 / DNA組換え / Tip60複合体 / Tad54α / Tap54α-K76R / DNA複製ライセンス化反応 / MCM複合体 / クロマチン / ライセンス化 / 新生DNA鎖伸長反応 / Blm症候群 / Blm / DNA複製フォーク停止 / DNA複製前複合体 / Mcm複合体 / Cdc7 / 生化学 / DNA組え修復 / ポリADPリボシルポリメラーゼ / 遺伝子構造安定性維持 / 質量分析 / ユビキチン化 / ニワトリDT40細胞 / ゲノム安定性 / RECQL4 / CDT1 / Bloom症候群 / Werner症候群 / DNA Topoisomerase IIIα / 相同組み換え修復 / RecQ helicases / Bloom syndrome / Werner syndrome / Rothmund-Thomson syndrome / DNA topoisomerase IIIα / homologous recombination repair / 遺伝子構造安定性維持機構 / RecQファミリー / DNA-PK / maintenance of genomic integrity / RecQ-family DNA helicases / DNA double strand break repair / RecQ4 / 新生鎖伸長反応 / ゲノム安定性維持機構 / gemnin / DNA鎖伸長反応 … More Except Principal Investigator NAD / RecQ / SGS1 / DNA修復 / RecQホモローグ / アルキル化剤 / ブルーム症候群 / TPS1 / 遺伝子破壊株 / 胞子形成 / ウェルナー症候群 / 早期老化 / WRN / WRNIP1 / RAD18 / DNA損傷回避 / 複製フォーク / ユビキチン化 / WPN / RAK18 / WRNTP1 / 中心体 / 細胞周期 / 中心体複製 / 分裂期 / セパレース / 複製ライセンシング / 肝臓細胞 / 食細胞 / GTP結合蛋白質 / 細胞増殖 / PI-3-キナーゼ / ワ-トマニン / チロシンキナーゼ / 細胞接着 / 3量体G蛋白質 / 肝臓初代培養 / betaアドレナリン受容体 / alpha_1アドレナリン受容体 / Gs / Gq / G蛋白質 / Caチャネル / 肝蔵細胞 / 細胞分化 / HL-60細胞 / 3T3細胞 / 百日咳毒素 / heterotrimeric G proteins / cell differentiation / cell adhesion / wortmannin / PI 3-kinase / protein tyrosine phosphorylation / pertussis toxin / adrenergic receptor / 環状ADPリボース / NAD代謝酵素 / ADPリボース環化酵素 / ヒトリンパ球表面抗原CD38 / ラジオイムノアッセイ / 情報伝達 / カルシウムイオン / cyclic ADP-ribose / NAD-cleavage enzyme / ADP-ribosyl cyclase / CD38 / radioimmunoassay / signal transduction / DNA修復・組み換え / DNAヘリカーゼQ1 / トランスジェニックフライ / メチルメタンスルホン酸 / 減数分裂 / 精子形成 / Two-hybrid system / Rch1 / DNA repair-recombination / DNA helicae Q1 / Transgenic fly / Methyl methanesulfonate / Spermatogenesis / Meiosis Less

Study on the degeneration of genome structure caused by dyscontrol of DNA replication initiation and the mechanisms to defense itPrincipal Investigator
- Principal Investigator
  
  TADA Shusuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Mechanisms for the maintenance of genome stability that involves proteins for the initiation of DNA replication.Principal Investigator
- Principal Investigator
  
  TADA Shusuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
  Teikyo Heisei University
Functional analysis of separase and its novel substrate in the licensing of centrosome duplication
- Principal Investigator
  
  TAKAHASHI Mikiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo Heisei University
Analysis on the function and coalition of RecQL4, a product of a gene mutated in a progeria syndrome, in the DNA transactions.Principal Investigator
- Principal Investigator
  
  TADA Shusuke
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo Heisei University
  Tohoku University
Study on the functions of WRN and WRNIP1 that interacts with WRN
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Involvement of RecQL4, a progeria syndrome responsible gene product, into the mechanism to maintain stability of genome structure.Principal Investigator
- Principal Investigator
  
  TADA Shusuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
DNA複製前複合体構築の分子的機序とその異常に応じたクロマチン動態の変化Principal Investigator
- Principal Investigator
  
  多田周右
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Integrated analysis of proteins functioning in response to abnormalities in genomic structure.Principal Investigator
- Principal Investigator
  
  TASA Shusuke
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
染色体安定性維持に機能するヒストンアセチル化酵素Tip60複合体の生化学的解析Principal Investigator
- Principal Investigator
  
  多田周右
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
DNA複製過程の異常に起因するDNA構造異常とその解消・修復機構Principal Investigator
- Principal Investigator
  
  多田周右
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Analysis of the contribution of RecQ family proteins to a maintenance system of genetic information using cell-free experiment system.Principal Investigator
- Principal Investigator
  
  TADA Shusuke
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
DNA二本鎖切断による発がん機構に関する無細胞実験系による解析Principal Investigator
- Principal Investigator
  
  多田周右
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
「DNA複製」と「異常DNA構造の認識・修復」の共役機構に関する研究Principal Investigator
- Principal Investigator
  
  多田周右
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
真核細胞の新規DNA修復系の検出と修復機構の解析
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Novel Mechanism & Developmental Roles of Repair・Recombination
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tohoku University
哺乳類細胞のDNA複製に関与するDNAヘリカーゼの同定と機能の解析Principal Investigator
- Principal Investigator
  
  多田周右
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Development of Assay Methods for a Novel Intracellular Messenger, Cyclic ADP-ribose
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo (Faculty of Pharmaceutical Sciences)
Signal Transduction Systems for Cell Proliferation, Differentiation and Adhesion with Emphasis upon the Role of GTP-binding Proteins
- Principal Investigator
  
  UI Michio
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  代謝生物化学
- Research Institution
  The Institute of Physical and Chemical Chemical Research (RIKEN)
  The University of Tokyo

[Book] 分子生物学イラストレイテッド改訂第3版(DNAの複製)2009
- Author(s)
  多田周右、榎本武美
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Mutant analysis of Cdt1's function in suppressing nascent strand elongation during DNA replication in Xenopus egg extracts2017
- Author(s)
  Nakazaki Yuta、Tsuyama Takashi、Azuma Yutaro、Takahashi Mikiko、Tada Shusuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 490 Pages: 1375-1380
- DOI
  10.1016/j.bbrc.2017.07.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07948
[Journal Article] Excess Cdt1 inhibits nascent strand elongation by repressing the progression of replication forks in Xenopus egg extracts2016
- Author(s)
  Nakazaki Y, Tsuyama T, Seki M, Takahashi M, Enomoto T, Tada S.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 470 Pages: 405-410
- DOI
  10.1016/j.bbrc.2016.01.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07009, KAKENHI-PROJECT-15K07948, KAKENHI-PROJECT-26440065, KAKENHI-PROJECT-15H06638
[Journal Article] Wrnip1 functions upstream of DNA polymerase h in the UV-induced DNA damage response2014
- Author(s)
  Yoshimura, A., Kobayashi, Y., Tada, S., Seki, M., Enomoto, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 452 Pages: 48-52
- DOI
  10.1016/j.bbrc.2014.08.043
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590089, KAKENHI-PROJECT-26440065, KAKENHI-PLANNED-22131002
[Journal Article] Tipin functions in the protection against topoisomerase I inhibitor2014
- Author(s)
  Yoshifumi Hosono, Takuya Abe, Masato Higuchi, Kosa Kajii, Shuichi Sakuraba, Shusuke Tada, Takemi Enomoto, Masayuki Seki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Pages: 11374-11384
- DOI
  10.1074/jbc.m113.531707
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J07075, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-24590089, KAKENHI-PLANNED-22131002
[Journal Article] WRNIP1 accumulates at laser light irradiated sites rapidly via its ubiquitin-binding zinc finger domain and independently from its ATPase domain2012
- Author(s)
  Nomura, H., Yoshimura, A., Edo, T., Kanno, S.I., Tada, S., Seki, M., Yasui, A., and Enomoto, T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 417 Pages: 1145-1150
- DOI
  10.1016/j.bbrc.2011.12.080
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-24590089, KAKENHI-PLANNED-22131005
[Journal Article] Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc1.2012
- Author(s)
  Lai, M.S., *Seki, M., Tada, S., and Enomoto T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 417 Pages: 1145-1150
- DOI
  10.1016/j.bbrc.2012.09.124
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-24590089
[Journal Article] The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells. Role of the N-terminal region of RECQL4 in cells2011
- Author(s)
  Abe, T., Yoshimura, A., Hosono, Y., Tada, S., Seki, M., Enomoto. T
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1813 Pages: 473-479
- DOI
  10.1016/j.bbamcr.2011.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PROJECT-23370065
[Journal Article] Biphasic chromatin binding of FACT during DNA replication.2011
- Author(s)
  Kundu L.R., Seki M., Watanabe N., Murofusi H, Furukohri A., Waga S., Score A.J., Blow J.J., Horikoshi M., Enomoto T., Tada S.
- Journal Title
  
  Biochim.Biophys.Acta 1813
  
  Pages: 1129-1136
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library2011
- Author(s)
  K.Ishikawa, T.Ohsumi, S.Tada, R.Natsume, L.R.Kundu, N.Nozaki, T.Senda, T.Enomoto, M.Horikoshi & M.Seki
- Journal Title
  
  Genes Cells 16
  
  Volume: 16 Pages: 1050-1062
- DOI
  10.1111/j.1365-2443.2011.01549.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21590059, KAKENHI-PUBLICLY-22113502, KAKENHI-PLANNED-22121005, KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065
[Journal Article] Werner Interacting Protein 1 Promotes Binding of Werner Protein to Template-Primer DNA2011
- Author(s)
  Kanamori M, Seki, M, Yoshimura A, Tsurimoto T, Tada S, Enomoto T
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Issue: 8 Pages: 1314-1318
- DOI
  10.1248/bpb.34.1314
- NAID
  130000936605
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059
[Journal Article] The histone chaperone FACT maintains normal replication fork rates2011
- Author(s)
  T.Abe, K.Sugimura, Y.Hosono, Y.Takami, M.Akita, A.Yoshimura, S.Tada, T.Nakayama, H.Murofushi, K.Okumura, S.Takeda, M.Horikoshi, M.Seki & T.Enomoto
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 30504-30512
- DOI
  10.1074/jbc.m111.264721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PUBLICLY-22113502, KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-22380188, KAKENHI-PROJECT-22790281, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23370065
[Journal Article] Functional relationshipbetween Claspin and Rad172011
- Author(s)
  Yoshimura, A., Akita, M., Hosono, Y., Abe, T., Kobayashi, M., Yamamoto, K.I., Tada, S., Seki, M., Enomoto, T.
- Journal Title
  
  Biophys. Res. Commun
  
  Volume: 414 Pages: 298-303
- DOI
  10.1016/j.bbrc.2011.09.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PROJECT-22710052, KAKENHI-PROJECT-23370065
[Journal Article] Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication2011
- Author(s)
  Kundu L. R., Seki M., Watanabe N., Murofushi H., Furukohri A., Waga S., Score A. J., Blow J. J., Horikoshi M., Enomoto T., Tada S.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1813 Pages: 1129-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells.2011
- Author(s)
  Abe T., Yoshimura A., Hosono Y., Tada S., Seki M., Enomoto T.
- Journal Title
  
  Biochim.Biophys.Acta 1813
  
  Pages: 473-479
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA2010
- Author(s)
  Inoue E., Tano K., Yoshii H., Nakamura J., Tada S., Watanabe M., Seki M., Enomoto T.
- Journal Title
  
  J Nucleic Acids
  
  Volume: 2010 Pages: 795946-795946
- DOI
  10.4061/2010/795946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex.2010
- Author(s)
  Kundu L.R., Kumata Y., Kakusho N., Watanabe S., Furukohri A., Waga S., Seki M., Masai H., Enomoto T., Tada S.
- Journal Title
  
  Nucleic Acids Res. 38
  
  Pages: 5409-5418
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] SOD1 is essential for the viability of DT40 cells and nuclear SOD1 functions as a guardian of genomic DNA.2010
- Author(s)
  Inoue E., Tano K., Yoshii H., Nakamura J., Tada S., Watanabe M., Seki M., Enomoto T.
- Journal Title
  
  J.Nuc.Acids (in press)
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex2010
- Author(s)
  Kundu L. R., Kumata Y., Kakusho N., Watanabe S., Furukohri A., Waga S., Seki M., Masai H., Enomoto T., Tada S.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38 Pages: 5409-5418
- DOI
  10.1093/nar/gkq262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2.2009
- Author(s)
  Takada S., Inoue E., Tano K., Yoshii H., Abe T., Yoshimura A., Akita M., Tada S., Watanabe M., Seki M., Enomoto T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 379
  
  Pages: 233-238
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Physical and functional interaction between WRNIP1 and RAD182009
- Author(s)
  Yoshimura, A., Seki, M., Kanamori, M., Tateishi, S., Tsurimoto, T., Tada, S. and Enomoto, T.
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 84 Issue: 2 Pages: 171-178
- DOI
  10.1266/ggs.84.171
- NAID
  10024791852
- ISSN
  1341-7568, 1880-5779
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication2009
- Author(s)
  Ohuchi, T., Seki, M., Kugou, K., Tada, S., Ohta, K. and Enomoto, T.
- Journal Title
  
  DNA Repair
  
  Volume: 8 Pages: 690-696
- DOI
  10.1016/j.dnarep.2009.01.018
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts2009
- Author(s)
  Tsuyama, T., Watanabe, S., Aoki, A., Cho, Y., Seki, M., Enomoto, T., Tada, S.
- Journal Title
  
  Mol. Biol. Cell. 20
  
  Pages: 937-947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2. Biochem.2009
- Author(s)
  Takada, S., Inoue, E., Tano, K., Yoshii, H., Abe, T., Yoshimura, A., Akita, M., Tada, S., Watanabe, M., Seki, M., Enomoto, T.
- Journal Title
  
  Biophys. Res. Commun 379
  
  Pages: 233-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Structure of the Cdt1 C-terminal domain : Conservation of the winged helix fold in replication licensing factors2009
- Author(s)
  Khayrutdinov, B. I., Bae, W. J., Yun, Y. M., Lee, J. H., Tsuyama, T., Kim, J. J., Hwang, E., Ryu, K. S., Cheong, H. K., Cheong, C., Ko, J. S., Enomoto, T., Karplus, P. A., Guntert, P., Tada, S., Jeon, Y. H., and Cho, Y.
- Journal Title
  
  Protein Sci
  
  Volume: 18 Pages: 2252-2264
- DOI
  10.1002/pro.236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication.2009
- Author(s)
  Ohuchi T., Seki M., Kugou K., Tada S., Ohta K., Enomoto T.
- Journal Title
  
  DNA Repair 8
  
  Pages: 690-696
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication2009
- Author(s)
  Ohuchi, T., Seki, M., Kugou, K., Tada, S., Ohta, K., Enomoto, T.
- Journal Title
  
  DNA Repair (Amst) (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Repression of nascent strandelongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts2009
- Author(s)
  Tsuyama, T., Watanabe, S., Aoki, A., Cho, Y., Seki, M., Enomoto, T. and Tada, S.
- Journal Title
  
  Mol. Biol
  
  Volume: 20 Pages: 937-947
- DOI
  10.1091/mbc.e08-06-0613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590059
[Journal Article] Physical and functional interaction between WRNIP1 and RAD18.2009
- Author(s)
  Yoshimura A., Seki M., Kanamori M., Tateishi S., Tsurimoto T., Tada S., Enomoto T.
- Journal Title
  
  Genes Genet.System 84
  
  Pages: 171-178
- NAID
  10024791852
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.2009
- Author(s)
  Tsuyama T., Watanabe S., Aoki A., Cho Y., Seki M., Enomoto T., Tada S.
- Journal Title
  
  Mol.Bio.Cell 20
  
  Pages: 937-947
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Insight into initiator-DNA interactions : a lesson from the archaeal ORC2008
- Author(s)
  Shusuke Tada, et.al.
- Journal Title
  
  Bioessays 30
  
  Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Insight into initiator-DNA interactions: a lesson from the archaeal ORC.2008
- Author(s)
  Shusuke Tada, et. al.
- Journal Title
  
  Bioessays 30
  
  Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIa.2008
- Author(s)
  Otsuki M., Seki M., Inoue E., Abe T., Narita Y., Yoshimura A., Tada S., Ishii Y., Enomoto T.
- Journal Title
  
  Biochim.Biophys.Acta 1782
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] A novel role for Rad17 in homologous recombination2008
- Author(s)
  Nishino, K., Inoue, E., Takada, S., Abe, T., Akita, M., Yoshimura, A., Tada, S., Kobayashi, M., Yamamoto, K., Seki, M., Enomoto, T.
- Journal Title
  
  Genes. Genet. Syst 83
  
  Pages: 427-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Vertebrate WRNIP1 and BLM are required for efficient maintenance of genome stability.2008
- Author(s)
  Hayashi T., Seki M., Yoshimura A., Inoue E., Kusa Y., Tada S., Enomoto T.
- Journal Title
  
  Genes Genet.Syst. 83
  
  Pages: 95-100
- NAID
  10024395708
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase III2008
- Author(s)
  Otsuki, M., Seki, M., Inoue, E., Abe, T., Narita, Y., Yoshimura, A., Tada, S., Ishii, Y., Enomoto, T.
- Journal Title
  
  Biochim. Biophys. Acta 1782
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation2008
- Author(s)
  Abe, T., Ishiai, M., Hosono, Y., Yoshimura, A., Tada, S., Adachi, N., Koyama, H., Takata, M., Takeda, S., Enomoto, T., Seki, M.
- Journal Title
  
  Cell Signal 20
  
  Pages: 1978-1985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Insight into initiator-DNA interactions : a lesson from the archaeal ORC2008
- Author(s)
  Tada, S., Kundu, L. R., Enomoto, T.
- Journal Title
  
  Bioessays 30 30
  
  Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Insight into initiator-DNA interactions: a lesson from the archaeal ORC.2008
- Author(s)
  Shusuke Tada, et. al.
- Journal Title
  
  Bioessays 30
  
  Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18058002
[Journal Article] Rad52 sumoylation and its involvement in the efficient induction of homologous recombination2008
- Author(s)
  Ohuchi, T., Seki, M., Branzei, D., Maeda, D., Ui, A., Ogiwara, H., Tada, S., Enomoto, T.
- Journal Title
  
  DNA Repair (Amst) 7
  
  Pages: 879-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Vertebrate WRNIP1 and BLM are required for efficient maintenance of genome stability. Genes2008
- Author(s)
  Hayashi, T., Seki, M., Inoue, E., Yoshimura, A., Kusa, Y., Tada, S., Enomoto, T.
- Journal Title
  
  Genet. Syst 83
  
  Pages: 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] RecQ family helicases in genome stability : lessons from gene disruption studies in DT40 cells2008
- Author(s)
  Seki, M., Otsuki, M., Ishii, Y., Tada, S., Enomoto, T.
- Journal Title
  
  Cell Cycle 7
  
  Pages: 2472-2478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation.2008
- Author(s)
  Abe T., Ishiai M., Hosono Y., Yoshimura A., Tsuji H., Tada S., Adachi N., Koyama H., Takata M., Takeda S., Enomoto T., Seki M.
- Journal Title
  
  Cell Signal. 20
  
  Pages: 1978-1985
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Rad52 sumoylation and its involvement in the efficient induction of homologous recombination.2008
- Author(s)
  Ohuchi T., Seki M., Branzei D., Maeda D., Ui A., Ogiwara H., Tada S., Enomoto T.
- Journal Title
  
  DNA Repair 7
  
  Pages: 879-889
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Cdt1 and geminin : role during cell cycle progression and DNA damage in higher eukaryotes2007
- Author(s)
  Tada, S.
- Journal Title
  
  Front. Biosci 12
  
  Pages: 1629-1641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] The INO80 complex is required for damage-induced recombination2007
- Author(s)
  Kawashima, S., Ogiwara, H., Tada, S., Harata, M., Wintersberger, U., Enomoto, T., Seki, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun 355
  
  Pages: 835-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Rad50 is involved in MMS-induced recombination between homologous chromosomes in mitotic cells2007
- Author(s)
  Tomizawa, Y., Ui, A., Onoda, F., Ogiwara, H., Tada, S., Enomoto, T., Seki, M.
- Journal Title
  
  Genes. Genet. Syst 82
  
  Pages: 157-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Cdtl and geminin : role during cell cycle progression and DNA damage in higher eukaryotes.2007
- Author(s)
  Shusuke Tada
- Journal Title
  
  Frontiers in Bioscience 12
  
  Pages: 1629-1641
- Data Source
  KAKENHI-PROJECT-18058002
[Journal Article] Functional interactions between BLM and XRCC3 in the cell2007
- Author(s)
  Otsuki, M., Seki, M., Inoue, E., Yoshimura, A., Kato, G., Yamanouchi, S., Kawabe, Y., Tada, S., Shinohara, A. Komura, J., Ono, T., Takeda, S., Ishii, Y., Enomoto, T.
- Journal Title
  
  J. Cell Biol 179
  
  Pages: 53-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Ctf18 is required for homologous recombination-mediated double-strand break repair2007
- Author(s)
  Ogiwara, H., Ohuchi, T., Ui, A., Tada, S., Enomoto, T., Seki, M.
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 4989-5000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] WRN counteracts the NHEJ pathway upon camptothecin exposure2007
- Author(s)
  Otsuki, M., Seki, M., Kawabe, Y., Inoue, E., Dong, Y. P., Abe, T., Kato, G., Yoshimura, A., Tada, S., Enomoto, T.
- Journal Title
  
  Biochem. Biophys. Res. 355
  
  Pages: 477-482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Activation of a novel pathway involving Mms1 and Rad59 in sgs1 cells2007
- Author(s)
  Ui, A., Seki, M., Ogiwara, H., Lai, M. S., Yamamoto, K., Tada, S., Enomoto, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 356
  
  Pages: 1031-1037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Cdt1 and geminin : role during cell cycle progression and DNA damage in higher eukaryotes.2007
- Author(s)
  Shusuke Tada
- Journal Title
  
  Frontiers in Bioscience 12
  
  Pages: 1629-1641
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts2007
- Author(s)
  Kumata, Y., Tada, S., Yamanada, Y., Tsuyama, T., Kobayashi, T., Dong, Y. P., Ikegami, K., Murofushi, H., Seki, M., Enomoto, T.
- Journal Title
  
  Biochim. Biophys. Acta 1773
  
  Pages: 556-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] WRN functions in a RAD18-dependent damage avoidance pathway2007
- Author(s)
  Dong, Y. P., Seki, M., Yoshimura, A., Inoue, E., Furukawa, S., Tada, S., Enomoto, T.
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 1080-1108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590053
[Journal Article] Cdtl and geminin : role during cell cycle progression and DNA damage in higher eukaryotes.2007
- Author(s)
  Shusuke Tada
- Journal Title
  
  Frontiers in Bioscience 12
  
  Pages: 1629-1641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] DNA helicases and progeroid syndromes (in Japanese).2006
- Author(s)
  Shusuke Tada, et al.
- Journal Title
  
  Seikagaku 78
  
  Pages: 221-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] DNAヘリカーゼと早老症.2006
- Author(s)
  多田周右ほか
- Journal Title
  
  生化学 78
  
  Pages: 221-229
- NAID
  10018120071
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] Cdt1 and geminin : role during cell cycle progression and DNA damage in higher eukaryotes.2006
- Author(s)
  Shusuke Tada
- Journal Title
  
  Frontiers in Biosciences (印刷中)
- Data Source
  KAKENHI-PROJECT-16026204
[Journal Article] ヘリカーゼと早老症2006
- Author(s)
  多田周右
- Journal Title
  
  生化学 78(3)(印刷中)
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] 細胞レベルで見たヒトRecQヘリカーゼ病(Werner症候群など).2006
- Author(s)
  多田周右ほか
- Journal Title
  
  病理と臨床 24
  
  Pages: 1299-1302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] ヘリカーゼと早老症2006
- Author(s)
  多田周右
- Journal Title
  
  生化学 78(3)(印刷中)
- Data Source
  KAKENHI-PROJECT-16026204
[Journal Article] Cellular feature of human syndromes defective in RecQ helicases (in Japanese).2006
- Author(s)
  Shusuke Tada, et al.
- Journal Title
  
  Pathology and Clinical Medicine (Byori to Rinsho) 24
  
  Pages: 1299-1302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] Cdt1 and geminin : role during cell cycle progression and DNA damage in higher eukaryotes.2006
- Author(s)
  Shusuke Tada
- Journal Title
  
  Frontiers in Biosciences (印刷中)
- Data Source
  KAKENHI-PROJECT-17590051
[Journal Article] Caenorhabditis elegans geminin homologue particpates in cell cycle regulation and germline development.2005
- Author(s)
  Yanagi, K.-I., Mizuno, T., Tsuyama, T., Tada, S., Iida, Y., Sugimoto, A., Eki, T., Enomoto, T., Hanaoka, F.
- Journal Title
  
  J.Biol.Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts.2005
- Author(s)
  Tsuyama, T., Tada, S., Watanabe, S., Seki, M., Enomoto, T.
- Journal Title
  
  Nucleic Acids Res. 33
  
  Pages: 765-775
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] Bloom症候群原因遺伝子産物の機能2004
- Author(s)
  多田周右
- Journal Title
  
  医学のあゆみ 208
  
  Pages: 863-869
- Data Source
  KAKENHI-PROJECT-16026204
[Journal Article] Bloom症候群原因遺伝子産物の機能2004
- Author(s)
  多田周右
- Journal Title
  
  医学のあゆみ 208
  
  Pages: 863-869
- Data Source
  KAKENHI-PROJECT-16021204
[Journal Article] Structural basis for inhibition of the replication licensing factor Cdt1 by geminin.2004
- Author(s)
  Lee, C., Hong, B., Choi, J.M., Kim, Y., Watanabe, S., Ishimi, Y., Enomoto, T., Tada, S., Kim, Y., Cho, Y.
- Journal Title
  
  Nature 430
  
  Pages: 913-917
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] Bloom症候群原因遺伝子産物の機能2004
- Author(s)
  多田周右
- Journal Title
  
  医学のあゆみ 208
  
  Pages: 863-869
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] Bloom症候群原因遺伝子産物の機能2004
- Author(s)
  多田周右, 榎本武美
- Journal Title
  
  医学のあゆみ 208
  
  Pages: 863-869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] Function of Bloom syndrome gene product2004
- Author(s)
  Tada, S., Enomoto, T.
- Journal Title
  
  Journal of Clinical and Experimental Medicine 208
  
  Pages: 863-869
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] The absence of a functional relationship between ATM and BLM, the components of BASC, in DT40 cells.2004
- Author(s)
  Wang, W., Seki, M., Otsuki, M., Tada, S., Takao, N., Yamamoto, K., Hayashi, M., Honma, M., Enomoto, T.
- Journal Title
  
  Biochim.Biophys.Acta. 1688
  
  Pages: 137-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Journal Article] Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation.2003
- Author(s)
  Wang, W., Seki, M., Narita, Y., Nakagawa, T., Yoshimura, A., Otsuki, M., Kawabe, Y., Tada, S., Yagi, H., Ishii, Y., Enomoto, T.
- Journal Title
  
  Mol Cell Biol. 23
  
  Pages: 3527-3535
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590054
[Presentation] 非相同末端結合修復における RecQ4 の機能の解析2018
- Author(s)
  濱中汐里, 外山雄基, 佐々木良輔, 津山崇, 東祐太郎, 多田周右
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] アポトーシス誘発により増加するLewis型糖鎖の細胞貪食における役割とホスファチジルセリンとの関係2018
- Author(s)
  高畠史帆, 木村沙織, 東祐太郎, 津山崇, 多田周右
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] DNA複製阻害タンパク質Gemininの構造と機能に関する解析2017
- Author(s)
  後藤勇貴、井堀康太、山内直之、森洋介、中崎祐太、津山崇、東祐太郎、多田周右
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] アフリカツメガエル卵抽出液を用いたDNA複製におけるCdt1の新生鎖伸長抑制作用のメカニズムの解析2016
- Author(s)
  中崎祐太、津山崇、東祐太郎、高橋美樹子、多田周右
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] DNA複製ライセンス化機構におけるタンパク質間相互作用の生化学的解析2016
- Author(s)
  津山崇、中崎祐太、東祐太郎、多田周右
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 新生鎖伸長反応の抑制に関与するCdt1の機能領域とその作用機序に関する検討2016
- Author(s)
  中崎祐太, 津山崇, 東祐太郎, 高橋美樹子, 多田周右
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 細胞内タンパク質のO-GlcNAc 修飾によるbcl-2、bax の変化とアポトーシスへの影響2016
- Author(s)
  伊藤篤志、東祐太郎、大岩靖、秋谷美江、津山崇、多田周右
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] Cdt1によるDNA複製時の新生鎖伸長抑制作用に関するXenopus卵抽出液無細胞実験系を用いた解析2015
- Author(s)
  中崎祐太, 津山崇, 牛田磨理, 関政幸, 榎本武美, 高橋美樹子, 多田周右
- Organizer
  日本細胞生物学会第67回大会
- Place of Presentation
  タワーホール船堀（東京都・江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 抗がん剤によるCRTの細胞膜への移行とアポトーシスに関する解析2015
- Author(s)
  笹沼拓也、鈴木賢一、東祐太郎、多田周右
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 細胞内タンパク質のO-GlcNAc修飾によるアポトーシスの亢進とその機構の解析2015
- Author(s)
  秋谷美江、桜井美杏、東祐太郎、多田周右
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 抗がん剤により細胞表面CRTが増加した細胞に対するTSP1結合の解析2015
- Author(s)
  道工怜子、東祐太郎、多田周右
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] Cdt1の新生鎖伸長抑制作用に関与する機能領域の検討2015
- Author(s)
  中崎祐太, 牛田磨理, 津山崇, 関政幸, 榎本武美, 多田周右
- Organizer
  日本薬学会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（兵庫県神戸市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] WRNIP1のC末領域がPolη破壊株のUV感受性の制御に関与する2015
- Author(s)
  吉村明, 榊原達也, 多田周右, 関政幸, 榎本武美
- Organizer
  日本薬学会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（兵庫県神戸市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] 高濃度グルコース培養によるbcl2を介したアポトーシスの亢進とその機構の解析2015
- Author(s)
  大岩靖、君塚舜、東祐太郎、多田周右
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 5-FU による肝線維化増悪因子 TGFβ1 の発現制御と Sorafenib の効果2015
- Author(s)
  松井睦, 和田美希, 桧貝孝慈, 松尾和廣, 柳内和幸, 多田周右, 永井英成
- Organizer
  日本薬学会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（兵庫県神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] HIF-1α誘導刺激によるDPYD遺伝子発現上昇に対するSorafenibの効果2015
- Author(s)
  桧貝孝慈, 加藤由紀, 松本洸希, 松尾和廣, 多田周右, 永井英成
- Organizer
  日本薬学会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（兵庫県神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] アポトーシスを誘発したがん細胞株の貪食解析法の検討2015
- Author(s)
  高石慶吾、木内章人、東祐太郎、小林芳郎、多田周右
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 抗がん剤による小胞体タンパク質CRTの細胞膜への移行2015
- Author(s)
  佐藤達人、鈴木賢一、東祐太郎、多田周右
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K07948
[Presentation] 5-FUによる肝線維化増悪因子TGFβ1の発現制御とSorafenibの効果2015
- Author(s)
  和田美希、松井睦、桧貝孝慈、松尾和廣、柳内和幸、多田周右、永井英成
- Organizer
  日本肝がん分子標的治療研究会
- Place of Presentation
  海運クラブ（東京都千代田区）
- Year and Date
  2015-01-31
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] HIF-1α誘導刺激によるDPYD遺伝子発現調節とSorafenibの効果2014
- Author(s)
  加藤由紀、桧貝孝慈、松尾和廣、永井英成、多田周右
- Organizer
  日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学（東京都町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] NK細胞におけるNCR2遺伝子の転写調節制御2014
- Author(s)
  川名真代、伊藤健一郎、桧貝孝慈、松本宏治郎、多田周右
- Organizer
  日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学（東京都町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] 甘草由来化合物LicoagroauroneのNFkB阻害作用の解析2014
- Author(s)
  根本梨瑛、檜貝孝慈、李巍、小池一男、多田周右
- Organizer
  日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学（東京都町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] Cdt1によるDNA複製抑制作用に関する各種欠失変異体を用いた解析2014
- Author(s)
  中崎祐太, 牛田磨理, 津山崇, 関政幸, 榎本武美, 多田周右
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] The initiation of DNA replication is suppressed by Cdc6, a protein essential for the pre-replicative complex formation2009
- Author(s)
  多田周右, ほか
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590059
[Presentation] The initiation of DNA replication is suppressed by Cdc6, a proteinessential for the pre-replicative complex formation.2009
- Author(s)
  多田周右, ほか
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市・パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590059
[Presentation] WRNIP1のRAD18-RAD6複合体への結合と複合体のDNA結合に及ぼす影響2009
- Author(s)
  吉村明、金森允、多田周右、立石智、関政幸、榎本武美
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場(京都市)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] Cdc6によるDNA複製開始過程の抑制2008
- Author(s)
  Lena R. Kundu、熊田祐司、津山崇、関政幸、榎本武美、多田周右
- Organizer
  第19回DNA複製・分配ワークショップ2007年度組換え・染色体再編ワークショップ合同ワークショップ
- Place of Presentation
  伊豆市
- Year and Date
  2008-03-06
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Effects of deregulating Cdc6 during the initiation of DNA replication2008
- Author(s)
  Kundu, L. R., Kumata, Y., Tsuyama, T., Seki, M., Enomoto, T., Tada, S.
- Organizer
  The 6th 3R Symposium
- Place of Presentation
  The 6th 3R Symposium
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Significance of regulating Cdc6 during the initiation of DNA replication2008
- Author(s)
  Kundu, L. R., Kumata, Y., Tsuyama, T., Seki, M., Enomoto, T., Tada, S.
- Organizer
  NCRI Cancer Conference 2008
- Place of Presentation
  Birmingham, UK
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Nascent DNA elongation is repressed by deregulated Cdt1 in Xenopus egg extracts2008
- Author(s)
  津山崇、渡辺沙里、青木彩子、関政幸、榎本武美、多田周右
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Functional analysis of RecQL4 using RecQL4 mutated cells2008
- Author(s)
  Abe, T., Seki, M., Ikegami, K., Yoshimura, A., Tada, S., Enomoto, T.
- Organizer
  The 6th 3R Symposium
- Place of Presentation
  嬬恋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] 高等動物細胞におけるチェックポイント因子Claspinの機能の解析2008
- Author(s)
  秋田玄武、関政幸、吉村明、阿部拓也、多田周右、榎本武美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] RecQL4のDNA二本鎖切断誘発時における挙動の解析2008
- Author(s)
  池上京子、多田周右、Li Lan、安井明、関政幸、榎本武美
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] 異所的なCdt1活性に伴うDNA複製抑制機構の解析2008
- Author(s)
  津山崇、渡辺沙里、青木彩子、関政幸、榎本武美、多田周右
- Organizer
  第19回DNA複製・分配ワークショップ2007年度組換え・染色体再編ワークショップ合同ワークショップ
- Place of Presentation
  伊豆市
- Year and Date
  2008-03-06
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Inhibition of DNA Replication by the Replication Licensing Factor Cdc62008
- Author(s)
  Kundu, L. R., Tada, S., Kumata, Y., Tsuyama, T., Seki, M., Enomoto, T.
- Organizer
  Second JCA-AACR Special Joint Conference
- Place of Presentation
  淡路市
- Year and Date
  2008-07-15
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] WRNIP1はRAD18-RAD6に結合し、RAD18-RAD6のもつ複製フォーク様構造への結合を阻害する2008
- Author(s)
  吉村明、金森允、多田周右、立石智、関政幸、榎本武美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] SOD1枯渇によるゲノムの不安定化と細胞死はアスコルビン酸で抑制される2008
- Author(s)
  井上絵里、田野恵三、吉居華子、多田周右、渡邉正巳、関政幸、榎本武美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] DNA傷害に応じたRecQL4の動態と相互作用タンパク質の機能解明2008
- Author(s)
  池上京子、多田周右、Li Lan、菅野新一郎、安井明、関政幸、榎本武美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Repression of nascent strand elongation of DNA replication by deregulated Cdt1 in Xenopus egg extracts2008
- Author(s)
  Tsuyama, T., Watanabe, S., Aoki, A., Cho, Y., Seki, M., Enomoto, T., Tada, S.
- Organizer
  The 6th 3R Symposium
- Place of Presentation
  嬬恋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] WRNIP1はRAD18-RAD6に結合し、RAD18-RAD6のもつ複製フォーク様構造への結合を阻害する2008
- Author(s)
  吉村明、金森允、多田周右、立石智、関政幸、榎本武美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] ニワトリDT40細胞を用いた抗酸化酵素遺伝子破壊株の解析2007
- Author(s)
  井上絵里、関政幸、吉村明、櫻場秀一、多田周右、榎本武美
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] WRNIP1とRAD18の機能的連携の解明2007
- Author(s)
  吉村明、関政幸、多田周右、榎本武美
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Gemininは再複製時における複製フォークの停止を抑制する2007
- Author(s)
  津山崇、渡辺沙里、青木彩子、関政幸、榎本武美、多田周右
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡市
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Illegitimate activation of Cdt1 at S-phase possibly leads to a halt of nascent strand elongation in DNA re-replication.2007
- Author(s)
  Shusuke Tada, ほか
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Cdc6 inhibits the initiation of DNA replication by modulating Cdc7-dependent hyperphosphorylation of Mcm42007
- Author(s)
  Kundu, L. R., Kumata, Y., Tsuyama, T., Seki, M., Enomoto, T., Tada, S.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Eukaryotic DNA Replication and Genome Maintenance
- Place of Presentation
  New York, USA
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Illegitimate activation of Cdt1 at S-phase possibly leads to a halt of nascent strand elongation in DNA re-replication2007
- Author(s)
  多田周右、関政幸、榎本武美
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] 出芽酵母DNA polymerase δ Pol31サブユニットの機能ドメインの解析2007
- Author(s)
  井坂弘道、前田大介、Davoodi Vijeh Motlagh Niloofar、多田周右、関政幸、榎本武美
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] Illegitimate activation of Cdt1 at S-phase possibly leads to a halt of nascent strand elongation in DNA re-replication.2007
- Author(s)
  Shusuke Tadaほか
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18058002
[Presentation] DNA複製ライセンス化因子Cdt1の機能ドメインに関する生化学的解析2007
- Author(s)
  川端亮介、津山崇、多田周右、関政幸、榎本武美
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19590053
[Presentation] 遺伝子破壊細胞を用いたDNA複製フォーク構成因子Tipinのカンプトテシン毒性防御機構における機能の解析.
- Author(s)
  細野嘉史、梶井孔左、阿部拓也、樋口優人、多田周右、榎本武美、関政幸
- Organizer
  第２２回DNA複製・組換え・修復ワークショップ
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] DNA複製フォーク構成因子TipinのTop1阻害剤カンプトテシン処理時における役割.
- Author(s)
  梶井孔左、細野嘉史、阿部拓也、樋口優人、多田周右、榎本武美、関政幸
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] Pol η破壊株のUV感受性にWRNIP1の欠損が及ぼす影響の解析.
- Author(s)
  吉村明、多田周右、関政幸、榎本武美
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] WRNIP1欠損による Polη破壊株の UV 感受性抑制機構の解析.
- Author(s)
  吉村明、多田周右、関政幸、榎本武美
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] カンプトテシン存在下における DNA 複製フォーク構成因子 Tipin の機能解析.
- Author(s)
  梶井孔左、細野嘉史、阿部拓也、樋口優人、多田周右、榎本武美、関政幸
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590089
[Presentation] DNA複製ライセンス化因子 Cdt1 による DNA複製抑制作用に関与する機能領域についての検討.
- Author(s)
  中崎祐太、牛田磨理、津山崇、関政幸、榎本武美、多田周右
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590089

1. ENOMOTO Takemi (80107383)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
2. ISH-HOROWICZ David

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. HOSHINO Shin-ichi (40219168)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HAZEKI Osamu (80142751)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAHASHI Mikiko (90324938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MUKAI Hideyuki (80252758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUO Kazuhiko (70599753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UI Michio (50001037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HAZEKI Kaoru (50146007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KATADA Toshiaki (10088859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SEKI Masayuki (70202140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. TSUYAMA Takashi (70436096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. NAKAZAKI Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. GOTO Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. SUGIMURA Kazuto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. KANNO Shinichirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 堀越正美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 奥村克純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 武田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 小林昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tada Shusuke 多田 周右

TADA Shusuke 多田 周右

多田 周右 タダ シュウスケ

Research Projects

Research Products

Co-Researchers

Study on the degeneration of genome structure caused by dyscontrol of DNA replication initiation and the mechanisms to defense itPrincipal Investigator

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Mechanisms for the maintenance of genome stability that involves proteins for the initiation of DNA replication.Principal Investigator

Principal Investigator

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Functional analysis of separase and its novel substrate in the licensing of centrosome duplication

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Analysis on the function and coalition of RecQL4, a product of a gene mutated in a progeria syndrome, in the DNA transactions.Principal Investigator

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Study on the functions of WRN and WRNIP1 that interacts with WRN

Principal Investigator

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Involvement of RecQL4, a progeria syndrome responsible gene product, into the mechanism to maintain stability of genome structure.Principal Investigator

Principal Investigator

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DNA複製前複合体構築の分子的機序とその異常に応じたクロマチン動態の変化Principal Investigator

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Integrated analysis of proteins functioning in response to abnormalities in genomic structure.Principal Investigator

Principal Investigator

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染色体安定性維持に機能するヒストンアセチル化酵素Tip60複合体の生化学的解析Principal Investigator

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DNA複製過程の異常に起因するDNA構造異常とその解消・修復機構Principal Investigator

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Analysis of the contribution of RecQ family proteins to a maintenance system of genetic information using cell-free experiment system.Principal Investigator

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DNA二本鎖切断による発がん機構に関する無細胞実験系による解析Principal Investigator

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「DNA複製」と「異常DNA構造の認識・修復」の共役機構に関する研究Principal Investigator

Principal Investigator

Tada Shusuke 多田周右

TADA Shusuke 多田周右

多田周右タダシュウスケ