SHIMIZU Hiroshi 清水浩

… Alternative Names

SHIMIZU Hioroshi 清水浩

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Researcher Number	00226250
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院情報科学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 大阪大学, 大学院情報科学研究科, 教授 2011 – 2021: 大阪大学, 情報科学研究科, 教授 2009 – 2011: Osaka University, 大学院・情報科学研究科, 教授 2007: Osaka University, Graduate School of Information Science and Technology, Professor 2006: 大阪大学, 大学院情報科学研究科, 教授 … More 2003 – 2005: 大阪大学, 大学院・情報科学研究科, 教授 2004: 大阪大学, 情報科学研究科, 教授 1998 – 2001: 大阪大学, 大学院・工学研究科, 助教授 1995 – 1997: Department of Biotechnology, Faculty of Engineering. Osaka University, Associate, 工学部, 助教授 1990 – 1994: Faculty of Engineering, Osaka University, Assistant Professor, 工学部, 助手 Less
Review Section/Research Field	Principal Investigator Biofunction/Bioprocess / 生物・生体工学 / Basic Section 27040:Biofunction and bioprocess engineering-related / Medium-sized Section 62:Applied informatics and related fields / Medium-sized Section 27:Chemical engineering and related fields / Broad Section D / Chemical engineering and related fields / Biofunction/Bioprocess / Biological Sciences / Bioinformatics/Life informatics … More Except Principal Investigator … More 生物・生体工学 / 化学工学 / Broad Section D / Biological Sciences / Biofunction/Bioprocess Less
Keywords	Principal Investigator 代謝フラックス / 代謝フラックス解析 / ゲノムスケールモデル / シミュレーション / 光合成 / 指向性進化 / 生物情報工学 / ゲノムスケール代謝モデル / 代謝工学 / 物質生産 … More / 進化工学 / ストレス耐性 / DNAマイクロアレイ / 代謝反応モデル / 代謝評価 / RBS / 変動光 / 有用物質生産 / マイクロリアクタ / ロボット / 代謝解析 / がん細胞 / インシリコデザイン / 反応速度論 / システムバイオロジー / システムバイオテクノロジー / システム生物学 / microbial production / Genome scale model / isotope trace experiment / metabolic flux analysis / in silica prediction / 微生物生産 / 同位体標識トレース実験 / インシリコ代謝変動予測 / Model Predictive Controller / Multivariable Controller / Block Copolymer / Random Copolymer / Mole Fraction of Monomer Units / Metabolic Engineering / Biodegradable polymer / 分解特性 / モデル予測制御 / 多変数制御 / ブロック共重合 / ランダム共重合 / モル分率 / 生分解性ポリマー / maltose / dissolved oxygen concentration / bacteriocin / cascade controller / nisin / mixed culture / yeasts / lactic acid bacteria / ラクトース / マルトース / 溶存酸素濃度 / バクテリオシン / カスケード制御 / ナイシン / 混合培養 / 酵母 / 乳酸菌 / マルチオミクス / 強光条件 / 微細藻類 / 比増殖速度 / 発現プロファイル / バイオプロダクション / 変異解析 / ゲノム / ダイナミクス解析 / フローサイトメータ / 細胞集団 / 生物ネットワーク / ダイナミクス / GFP / 連続培養系 / フローサイトメトリー / 適応 / 細胞間相互作用 / 生命体情報ネットワーク / 大腸菌 / 形態変化 / 抗生物質生産 / オートレギュレータ / 糸状菌 / 画像解析 / エラーベクトル / 代謝反応モルフラックス / ファジィメンバシップ関数 / 状態認識 / ファジィ理論 … More Except Principal Investigator Enterococcus faecium / 乳酸菌 / Lactobacillus kefiranofaciens / E.faecium / シャトルベクター / バクテリオシン / エンテロシンA / Lactic acid bacteria / 酵母 / NMR / PHB / Specific growth rate / モデル化 / PF System / 比増殖速度 / バイオものづくり / 育種 / 代謝解析 / 気相反応 / 微生物 / エネルギー / 電子伝達 / 葉緑体 / 光合成 / kefiran / mathematical modeling / co-culture / yeast / ケフィラン / 共培養 / Structure of sugar moiety / Shuttle vector / Bacteriocin / EnterocinA / 糖鎖構造 / immunity for enterocin A / E. faecium / shuttle vector / bacteriocin / enterocin A / Lactobacillus plantarum / 発酵食品 / バクテリオシン耐性遺伝子 / wavelet filter / fault diagnosis / autoassociative neural network / temperature controllable gene expression / ウェーブレット変換 / 状態認識 / ウェーブレットフィルタ / 自己想起型ニューラルネットワーク / 異常診断 / 温度感受性組換え酵母 / Antibiotic nisin / Mixed culture / Flowcytometry / Propionic acid bacteria / Synergic interaction / Yeast / フローサイトメータ / マルトオリゴ糖 / ウィスキー醸造 / 抗菌物質ナイシン / 混合培養 / フローサイトメトリー / プロピオン酸菌 / Two-stage production / Acidic phosphatase / Rice-alpha-amylase / Temperature-sensitive / Recombinant yeast / 酸性ホスファタ-ゼ / ∂ーアミラ-ゼ / 2段培養 / 酸性ホスファターゼ / α-アミラーゼ / 温度感受性 / 遺伝子組み換え酵母 / control of substrate concentration / mole fraction in copolymer / molecular weight distribution / P(HB-co-HV) / biodegradable polymer / GPC / 高分子重合度 / 残存生物量 / ポリヒドロキシ酪酸 / 生分解性ポリマ- / 一次マルコフ鎖過程 / P(HB-HV)共重合物 / 基質濃度制御 / 共重合分率 / 分子量分布 / P(HB-co-HV)共重合物 / 生分解性ポリマー / Optimal profile of mu / Maximum principle / Specific production rate of glutathione / Extended Kalman filter / Estimation and control system / Glutathione / 最適化 / PFystem / 最適バタ-ン / 拡張カルマンフイルタ- / グルタチオン比生産速度 / 最適パタ-ン / 最大原理 / 拡張カルマンフィルタ- / 推定制御系 / グルタチオン化生産速度 / グルタチオン Less

リボゾーム結合部位配列の改変による大腸菌代謝フラックスの制御と物質生産への応用Principal Investigator
- Principal Investigator
  
  清水浩
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  The University of Osaka
A Study of Science and Process Construction of Microbial Gas-phase Reaction
- Principal Investigator
  
  堀克敏
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section D
- Research Institution
  Nagoya University
Systems analysis of photosynthesis and metabolism of cyanobacteria under fluctuation light conditionPrincipal Investigator
- Principal Investigator
  
  Shimizu Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Osaka University
High performance microbial cell factories development by model based metabolic design and adaptive laboratory evolutionPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section D
- Research Institution
  Osaka University
Identification of rate limiting step in metabolic pathway for bioproductions based on genome scale modelPrincipal Investigator
- Principal Investigator
  
  清水浩
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Osaka University
Development of Simulation System of Cancer MetabolismPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Chemical engineering and related fields
- Research Institution
  Osaka University
Intracellular metabolism control of the proton motive forcePrincipal Investigator
- Principal Investigator
  
  Shimizu Hiroshi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Identification of Limiting Step and Optimization of Metabolism based on Analysis of Dynamic Behaviors of Multilayers Omics DataPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
New Photosynthesis : Re-optimization of the solar energy conversion system
- Principal Investigator
  
  Minagawa Jun
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Basic Biology
Creation of Stress Tolerant Microbial Cell Factories based on Multiomics Analysis of Laboratory Evolution ProcessPrincipal Investigator
- Principal Investigator
  
  SHIMIZU HIROSHI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
Study on inhibitory effect of high light on the cell growth and adaptation mechanism of cyanobacteriaPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
Creation of stress tolerant strain based on single nucleotide mutational analysis of in whole genomePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
In silica Design of Metabolic Pathway of Yet for Bio-ProductionofEnvironmental-Conscious Chemical ProductsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
大腸菌細胞間相互作用をとおしてみた生命体情報ネットワークPrincipal Investigator
- Principal Investigator
  
  清水浩
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Osaka University
Development of Strategy for Fermentative Production Based on Symbiosis of Microorganisms
- Principal Investigator
  
  SHIOYA Suteaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Osaka University
Analysis of sugar moiety of enterocin from Enterococcus faecium N15
- Principal Investigator
  
  SHIOYA Suteaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
Quality Control of a Biodegradable Polymer using A Multivariable Controller, based on Metabolic Pathway InformaionPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
Isolation of a novel bacteriocin-producing lactic acid bacteria and its use in food preservation
- Principal Investigator
  
  SHIOYA Suteaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
Development of a novel controller for antimicrobial nisin production, using interaction of microorganismsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
Development of an on-line fault diagnosis and operation system for an optimal rice-alphaamylase production process of temperature-sensitive mutant of Saccharomyces cerevisiae by autoassociative neural network
- Principal Investigator
  
  SHIOYA Suteaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
画像処理装置を用いた放線菌の形態解析と抗生物質最大生産への応用Principal Investigator
- Principal Investigator
  
  清水浩
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
ファジィ理論と代謝反応モデルを用いた培養状態認識法の開発Principal Investigator
- Principal Investigator
  
  清水浩
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
The Role of Lactic Acid Bacteria and its Application to Fermentation Processes by Ecosystem Engineering Approach.
- Principal Investigator
  
  SHIOYA Suteaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
Computer Control of Biodegradable Polymer Production Process by Alcaligenes eutrophus
- Principal Investigator
  
  SUGA Ken-ichi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  化学工学
- Research Institution
  Osaka University
Construction of Useful Temperature-dependent Gene Expresssion System in S. cerevisiae and It's Application to a Cultivation Process
- Principal Investigator
  
  SHIOYA Suteaki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  化学工学
- Research Institution
  Osaka University
Computer Control of Glutathione Production Process by Saccharomycescerevisiae
- Principal Investigator
  
  SHIOYA Suetaki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  化学工学
- Research Institution
  Osaka University

[Book] 微生物を活用した有用物質の製造技術第3章化成品原料の生産、13C代謝フラックス解析を利用したイソプロピルアルコール生産大腸菌の代謝改良2023
- Author(s)
  清水浩
- Total Pages
  8
- Publisher
  CMC出版
- ISBN
  9784781317403
- Data Source
  KAKENHI-PROJECT-19H05626
[Book] 光合成第Ⅳ部、3. 光合成のカギとなる段階を探せ2021
- Author(s)
  清水浩、豊島正和
- Total Pages
  224
- Publisher
  朝倉書店
- ISBN
  9784254171761
- Data Source
  KAKENHI-PROJECT-21K19825
[Book] 代謝センシング　-健康,食,美容,薬,そして脳の代謝を知る-　第25章　動物培養細胞の13C代謝フラックス解析2018
- Author(s)
  岡橋伸幸、松田史生、清水浩
- Publisher
  シーエムシー出版
- ISBN
  9784781313504
- Data Source
  KAKENHI-PROJECT-17K19012
[Book] BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 4: Indsutrial Biotechnology Products and Processes, Chapter 11. Glutamic acid fermentation: Discovery of glutamic acid-producing microorganisms, analysis of the production mechanism, metabolic engineering and industrial production process2017
- Author(s)
  Takashi Hirasawa and Hiroshi Shimizu
- Total Pages
  22
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-16H04576
[Book] BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 5: Applied Bioengineering: Innovations and Future Directions, Chapter 8, Control of Microbial Processes2017
- Author(s)
  Kazuyuki Shimizu, Hiroshi Shimizu, Toshiomi Yoshida,
- Total Pages
  22
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-16H04576
[Book] BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 5: Applied Bioengineering: Innovations and Future Directions, Chapter 7, Omics integrations for the state analysis of microbial processes2017
- Author(s)
  Hiroshi Shimizu, Chikara Fursawa, Takashi Hirasawa, KatsunoriYoshikawa, Yoshihiro Toya, Tomokazu Shirai, and Fumio Matsuda
- Total Pages
  36
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-16H04576
[Book] BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 5: Applied Bioengineering: Innovations and Future Directions, Chapter 7, Omics integrations for the state analysis of microbial processes2017
- Author(s)
  Hiroshi Shimizu, Chikara Fursawa, Takashi Hirasawa, Katsunori Yoshikawa, Yoshihiro Toya, Tomokazu Shirai, and Fumio Matsuda
- Total Pages
  36
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PLANNED-16H06559
[Book] Chapter 17 Glutamic Acid2014
- Author(s)
  Takashi Hirasawa and Hiroshi Shimizu
- Total Pages
  22
- Publisher
  Weiley
- Data Source
  KAKENHI-PROJECT-24246134
[Book] 合成生物工学の隆起 ―有用物質の新たな生産法構築をめざして― 第3章　オミクス解析の視点2012
- Author(s)
  清水　浩
- Total Pages
  10
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-24246134
[Book] バイオにもコンピュータが役立つってホント？ひらく、ひらく「バイオの世界」、14歳からの生物工学入門2012
- Author(s)
  清水　浩
- Total Pages
  2
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24246134
[Book] バイオ素材から樹脂原料2012
- Author(s)
  清水　浩
- Total Pages
  14
- Publisher
  日経新聞
- Data Source
  KAKENHI-PROJECT-24246134
[Book] 日経新聞2012
- Author(s)
  清水浩
- Total Pages
  14
- Publisher
  日本経済新聞社
- Data Source
  KAKENHI-PROJECT-23656526
[Book] 高等研報告書1005生物進化の持続性と転移(研究代表者津田一郎)2011
- Author(s)
  古澤力, 堀之内貴明, 清水浩
- Publisher
  第2章大腸菌の長期植え継ぎ培養における表現型・遺伝子型の網羅的解析
- Data Source
  KAKENHI-PROJECT-21360401
[Book] 高等研報告書1005,生物進化の持続性と転移,第2章大腸菌の長期植え継ぎ培養における表現型・遺伝子型の網羅的解析2011
- Author(s)
  古澤力, 堀之内貴明, 清水浩
- Publisher
  財団法人国際高等研究所
- URL
  http://www-shimizu.ist.osaka-u.ac.jp/
- Data Source
  KAKENHI-PROJECT-21360401
[Book] メタボロミクスの先端技術と応用第14章メタボロームデータを用いた代謝フラックス解析2008
- Author(s)
  清水浩、古澤力、白井智量
- Publisher
  シーエムシー出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Book] バイオプロダクション第4章 : メタボリックエンジニアリング2006
- Author(s)
  清水浩
- Total Pages
  195
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-18360395
[Book] Bioproduction Chapter 4 Metabolic Engineering2006
- Author(s)
  Hiroshi, ShimizuS (H., Chtake, ed.)
- Total Pages
  195
- Publisher
  Corona Inc
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Coupling and uncoupling growth and product formation for producing chemicals2024
- Author(s)
  Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume: - Pages: 103133-103133
- DOI
  10.1016/j.copbio.2024.103133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Multicolor optogenetics for regulating flux ratio of three glycolytic pathways using EL222 and CcaSR in Escherichia coli2023
- Author(s)
 Akagi Hayato、Shimizu Hiroshi、Toya Yoshihiro
- Journal Title
 
 Biotechnology and Bioengineering
 
 Volume: 121 Issue: 3 Pages: 1016-1025
- DOI
 10.1002/bit.28628
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19H05626
[Journal Article] Effects of n-butanol production on metabolism and the photosystem in Synechococcus elongatus PCC 7942 based on metabolic flux and target proteome analyses2023
- Author(s)
 Wada Keisuke、Uebayashi Kiyoka、Toya Yoshihiro、Putri Sastia Prama、Matsuda Fumio、Fukusaki Eiichiro、C. Liao James、Shimizu Hiroshi
- Journal Title
 
 J. Gen. Appl. Microbiol.
 
 Volume: 69 Issue: 4 Pages: 185-195
- DOI
 10.2323/jgam.2023.03.002
- ISSN
 0022-1260, 1349-8037
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K19825
[Journal Article] Functional evaluation of non-oxidative glycolysis in Escherichia coli in the stationary phase under microaerobic conditions2023
- Author(s)
  Miyoshi Kenta、Kawai Ryutaro、Niide Teppei、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 135 Issue: 4 Pages: 291-297
- DOI
  10.1016/j.jbiosc.2023.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Effect of light fluctuations on photosynthesis and metabolic flux in Synechocystis sp. PCC 68032023
- Author(s)
  Imada Tatsumi、Yamamoto Chiaki、Toyoshima Masakazu、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Biotechnology Progress
  
  Volume: - Issue: 3
- DOI
  10.1002/btpr.3326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19825
[Journal Article] Metabolic pathway design for growth-associated phenylalanine production using synthetically designed mutualism2022
- Author(s)
  Kawai Ryutaro、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Bioprocess and Biosystems Engineering
  
  Volume: 45 Issue: 9 Pages: 1539-1546
- DOI
  10.1007/s00449-022-02762-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Logistic Regression-Guided Identification of Cofactor Specificity-Contributing Residues in Enzyme with Sequence Datasets Partitioned by Catalytic Properties2022
- Author(s)
  Sugiki Sou、Niide Teppei、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  ACS Synthetic Biology
  
  Volume: 11 Issue: 12 Pages: 3973-3985
- DOI
  10.1021/acssynbio.2c00315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K04841, KAKENHI-PROJECT-19H05626
[Journal Article] バイオによるものづくりに貢献する機械学習・深層学習技術2022
- Author(s)
  徳山健斗、清水浩
- Journal Title
  
  化学工学
  
  Volume: 86 Pages: 161-164
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Metabolic pathway engineering for the non-growth-associated succinate production in Escherichia coli based on flux solution space2022
- Author(s)
  Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 134 Issue: 1 Pages: 29-33
- DOI
  10.1016/j.jbiosc.2022.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] 発酵生産プロセスにおけるDX：データ駆動型のリジン発酵自律制御システムの開発2022
- Author(s)
  徳山健斗、清水浩
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 80 Pages: 26-30
- NAID
  40022815673
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Recent advances in metabolic engineering?integration of in silico design and experimental analysis of metabolic pathways2021
- Author(s)
  Shimizu Hiroshi、Toya Yoshihiro
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 132 Issue: 5 Pages: 429-436
- DOI
  10.1016/j.jbiosc.2021.08.002
- NAID
  40022744384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Identification of a rate-limiting step in a metabolic pathway using the kinetic model and in?vitro experiment2021
- Author(s)
  Kitamura Sayaka、Shimizu Hiroshi、Toya Yoshihiro
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 131 Issue: 3 Pages: 271-276
- DOI
  10.1016/j.jbiosc.2020.10.008
- NAID
  40022515098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626, KAKENHI-PROJECT-18K04850
[Journal Article] Estimation of linear and cyclic electron flows in photosynthesis based on 13C-metabolic flux analysis2021
- Author(s)
  Yamamoto Chiaki、Toyoshima Masakazu、Kitamura Sayaka、Ueno Yoshifumi、Akimoto Seiji、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 131 Issue: 3 Pages: 277-282
- DOI
  10.1016/j.jbiosc.2020.11.002
- NAID
  40022515104
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Role of type I NADH dehydrogenase in Synechocystis sp. PCC 6803 under phycobilisome excited red light2021
- Author(s)
  Toyoshima Masakazu、Yamamoto Chiaki、Ueno Yoshifumi、Toya Yoshihiro、Akimoto Seiji、Shimizu Hiroshi
- Journal Title
  
  Plant Science
  
  Volume: 304 Pages: 110798-110798
- DOI
  10.1016/j.plantsci.2020.110798
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Acceleration of target production in co‐culture by enhancing intermediate consumption through adaptive laboratory evolution2021
- Author(s)
  Kawai Ryutaro、Toya Yoshihiro、Miyoshi Kenta、Murakami Manami、Niide Teppei、Horinouchi Takaaki、Maeda Tomoya、Shibai Atsushi、Furusawa Chikara、Shimizu Hiroshi
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 119 Issue: 3 Pages: 936-945
- DOI
  10.1002/bit.28007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15096, KAKENHI-PROJECT-19H05626
[Journal Article] Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC68032021
- Author(s)
  Yoshikawa Katsunori、Ogawa Kenichi、Toya Yoshihiro、Akimoto Seiji、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1
- DOI
  10.1038/s42003-021-01875-y
- NAID
  120007028956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06559, KAKENHI-PROJECT-19H05626
[Journal Article] Reactor control system in bacterial co‐culture based on fluorescent proteins using an Arduino‐based home‐made device2021
- Author(s)
  Kusuda Minori、Shimizu Hiroshi、Toya Yoshihiro
- Journal Title
  
  Biotechnology Journal
  
  Volume: 16 Issue: 12 Pages: 2100169-2100169
- DOI
  10.1002/biot.202100169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Thioredoxin pathway in Anabaena sp. PCC 7120: activity of NADPH-thioredoxin reductase C2021
- Author(s)
  Deschoenmaeker Frederic、Mihara Shoko、Niwa Tatsuya、Taguchi Hideki、Wakabayashi Ken-Ichi、Toyoshima Masakazu、Shimizu Hiroshi、Hisabori Toru
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: － Issue: 6 Pages: 709-719
- DOI
  10.1093/jb/mvab014
- NAID
  40022687787
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559, KAKENHI-PROJECT-18H03984, KAKENHI-PROJECT-20K21420, KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-19H03242, KAKENHI-PUBLICLY-21H00420
[Journal Article] Transcription Factor ArcA is a Flux Sensor for the Oxygen Consumption Rate inEscherichia coli2020
- Author(s)
  Nochino Naoya、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Biotechnology Journal
  
  Volume: 15 Issue: 6 Pages: 1900353-1900353
- DOI
  10.1002/biot.201900353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626, KAKENHI-PROJECT-18K04850
[Journal Article] Flux balance analysis of cyanobacteria reveals selective use of photosynthetic electron transport components under different spectral light conditions2020
- Author(s)
  Toyoshima Masakazu、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Photosynthesis Research
  
  Volume: 143 Issue: 1 Pages: 31-43
- DOI
  10.1007/s11120-019-00678-x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Flux controlling technology for central carbon metabolism for efficient microbial bio-production2020
- Author(s)
  Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume: 64 Pages: 169-174
- DOI
  10.1016/j.copbio.2020.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] 光照射により代謝フラックスをコントロールする技術の開発2020
- Author(s)
  戸谷吉博、清水浩
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 78 Pages: 31-32
- Data Source
  KAKENHI-PROJECT-19H05626
[Journal Article] Novel allosteric inhibition of phosphoribulokinase identified by ensemble kinetic modeling of Synechocystis sp. PCC 6803 metabolism2020
- Author(s)
  Nishiguchi Hiroki、Liao James、Shimizu Hiroshi、Matsuda Fumio
- Journal Title
  
  Metabolic Engineering Communications
  
  Volume: 11 Pages: e00153-e00153
- DOI
  10.1016/j.mec.2020.e00153
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559, KAKENHI-PLANNED-17H06303
[Journal Article] Assessment of Protein Content and Phosphorylation Level in Synechocystis sp. PCC 6803 under Various Growth Conditions Using Quantitative Phosphoproteomic Analysis2020
- Author(s)
  Toyoshima Masakazu、Tokumaru Yuma、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 16 Pages: 3582-3582
- DOI
  10.3390/molecules25163582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Prediction of Rate‐Limiting Reactions for Growth‐Associated Production Using a Constraint‐Based Approach2019
- Author(s)
  Tokuyama Kento、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Biotechnology Journal
  
  Volume: 14 Issue: 9 Pages: 1800431-1800431
- DOI
  10.1002/biot.201800431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00839
[Journal Article] Targeted proteome analysis of microalgae under high-light conditions by optimized protein extraction of photosynthetic organisms.2019
- Author(s)
  Toyoshima, M., Sakata, M., Ohnishi, K., Tokumaru, Y., Kato, Y., Tokutsu, R., Sakamoto, W., Minagawa, J., Matsuda, F., Shimizu, H.
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 127 Issue: 3 Pages: 394-402
- DOI
  10.1016/j.jbiosc.2018.09.001
- NAID
  40021846292
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06290, KAKENHI-PLANNED-16H06559, KAKENHI-PLANNED-16H06553
[Journal Article] High-yielding rice Takanari has superior photosynthetic response to a commercial rice Koshihikari under fluctuating light2019
- Author(s)
  Adachi Shunsuke、Tanaka Yu、Miyagi Atsuko、Kashima Makoto、Tezuka Ayumi、Toya Yoshihiro、Kobayashi Shunzo、Ohkubo Satoshi、Shimizu Hiroshi、Kawai-Yamada Maki、Sage Rowan F、Nagano Atsushi J、Yamori Wataru
- Journal Title
  
  Journal of Experimental Botany
  
  Volume: 70 Issue: 19 Pages: 5287-5297
- DOI
  10.1093/jxb/erz304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19164, KAKENHI-PROJECT-18K14386, KAKENHI-PROJECT-18KK0170, KAKENHI-PLANNED-16H06556, KAKENHI-PLANNED-16H06559, KAKENHI-PUBLICLY-19H04715, KAKENHI-PROJECT-18H02165, KAKENHI-PROJECT-18H02185
[Journal Article] 計算機工学に基づく代謝設計とその有効性の実証に関する研究2019
- Author(s)
  清水浩
- Journal Title
  
  生物工学誌
  
  Volume: 97 Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04576
[Journal Article] Time-resolved analysis of short term metabolic adaptation at dark transition in Synechocystis sp. PCC68032019
- Author(s)
  Maruyama Masaharu、Nishiguchi Hiroki、Toyohima Masakazu、Okahashi Nobuyuki、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience Bioengineering
  
  Volume: -
- NAID
  40022037144
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Transomics data-driven, ensemble kinetic modeling for system-level understanding and engineering of the cyanobacteria central metabolism2019
- Author(s)
  Nishiguchi Hiroki、Hiasa Natsuki、Uebayashi Kiyoka、Liao James、Shimizu Hiroshi、Matsuda Fumio
- Journal Title
  
  Metabolic Engineering
  
  Volume: 52 Pages: 273-283
- DOI
  10.1016/j.ymben.2019.01.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559, KAKENHI-PLANNED-17H06303
[Journal Article] Magnesium starvation improves production of malonyl-CoA-derived metabolites in Escherichia coli2019
- Author(s)
  Tokuyama Kento、Toya Yoshihiro、Matsuda Fumio、Cress Brady F.、Koffas Mattheos A.G.、Shimizu Hiroshi
- Journal Title
  
  Metabolic Engineering
  
  Volume: 52 Pages: 215-223
- DOI
  10.1016/j.ymben.2018.12.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04576
[Journal Article] Optimal 13 C-labeling of glycerol carbon source for precise flux estimation in Escherichia coli2018
- Author(s)
  Toya Yoshihiro、Ohashi Shugo、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 125 Issue: 3 Pages: 301-305
- DOI
  10.1016/j.jbiosc.2017.09.009
- NAID
  210000005652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04576
[Journal Article] Mass Spectrometry-Based Method to Study Inhibitor-Induced Metabolic Redirection in the Central Metabolism of Cancer Cells2018
- Author(s)
  Araki Chie、Okahashi Nobuyuki、Maeda Kousuke、Shimizu Hiroshi、Matsuda Fumio
- Journal Title
  
  Mass Spectrometry
  
  Volume: 7 Issue: 1 Pages: A0067-A0067
- DOI
  10.5702/massspectrometry.A0067
- NAID
  130007396785
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2018-06-14
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-17K19012
[Journal Article] Transcriptome analysis of the cyanobacterium Synechocystis sp. PCC 6803 and mechanisms of photoinhibition tolerance under extreme high light conditions2018
- Author(s)
  Ogawa Kenichi、Yoshikawa Katsunori、Matsuda Fumio、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 126 Issue: 5 Pages: 596-602
- DOI
  10.1016/j.jbiosc.2018.05.015
- NAID
  40021726334
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Metabolic engineering of mevalonate-producing Escherichia coli strains based on thermodynamic analysis2018
- Author(s)
  Nagai Hikaru、Masuda Ami、Toya Yoshihiro、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  Metabolic Engineering
  
  Volume: 47 Pages: 1-9
- DOI
  10.1016/j.ymben.2018.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06303, KAKENHI-PROJECT-16H04576
[Journal Article] Application of adaptive laboratory evolution to overcome a flux limitation in an Escherichia coli production strain2018
- Author(s)
  Tokuyama Kento、Toya Yoshihiro、Horinouchi Takaaki、Furusawa Chikara、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 115 Issue: 6 Pages: 1542-1551
- DOI
  10.1002/bit.26568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15052, KAKENHI-PROJECT-16H04576, KAKENHI-PROJECT-15J06350
[Journal Article] Comparative Targeted Proteomics of the Central Metabolism and Photosystems in SigE Mutant Strains of Synechocystis sp. PCC 68032018
- Author(s)
  Tokumaru Yuma、Uebayashi Kiyoka、Toyoshima Masakazu、Osanai Takashi、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 5 Pages: 1051-1051
- DOI
  10.3390/molecules23051051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Metabolic flux of the oxidative pentose phosphate pathway under low light conditions in Synechocystis sp. PCC 68032018
- Author(s)
  Ueda Kentaro、Nakajima Tsubasa、Yoshikawa Katsunori、Toya Yoshihiro、Matsuda Fumio、Shimizu Hiroshi
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: - Issue: 1 Pages: 38-43
- DOI
  10.1016/j.jbiosc.2018.01.020
- NAID
  40021601004
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Identification of alcohol stress tolerance genes of Synechocystis sp. PCC 6803 using adaptive laboratory evolution2017
- Author(s)
  Matsusako Takuya、Toya Yoshihiro、Yoshikawa Katsunori、Shimizu Hiroshi
- Journal Title
  
  Biotechnology for Biofuels
  
  Volume: 10 Issue: 1 Pages: 307-307
- DOI
  10.1186/s13068-017-0996-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Metabolic engineering of isopropyl alcohol-producing Escherichia coli strains with 13C-metabolic flux analysis2017
- Author(s)
  Okahashi Nobuyuki、Matsuda Fumio、Yoshikawa Katsunori、Shirai Tomokazu、Matsumoto Yoshiko、Wada Mitsufumi、Shimizu Hiroshi
- Journal Title
  
  Biotechnolgy and Bioengineering
  
  Volume: 114 Issue: 12 Pages: 2782-2793
- DOI
  10.1002/bit.26390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04576
[Journal Article] Metabolic engineering of Synechocystis sp. PCC 6803 for enhanced ethanol production based on flux balance analysis2017
- Author(s)
  Katsunori Yoshikawa, Yoshihiro Toya, Hiroshi Shimizu
- Journal Title
  
  Bioprocess and Biosystems Engineering
  
  Volume: 40 Issue: 5 Pages: 1-6
- DOI
  10.1007/s00449-017-1744-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Learning from quantitative data to understand central carbon metabolism2017
- Author(s)
  Matsuda Fumio、Toya Yoshihiro、Shimizu Hiroshi
- Journal Title
  
  Biotechnology Advances
  
  Volume: 35 Issue: 8 Pages: 971-980
- DOI
  10.1016/j.biotechadv.2017.09.006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06303, KAKENHI-PROJECT-16H04576
[Journal Article] 13C-metabolic flux analysis for mevalonate producing Escherichia coli2016
- Author(s)
  Keisuke Wada, Yoshihiro Toya, Satomi Banno, Katsunori Yoshikawa, Fumio Matsuda, Hiroshi Shimizu
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 123 Issue: 2 Pages: 177-182
- DOI
  10.1016/j.jbiosc.2016.08.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H04576
[Journal Article] Recent advances in amino acid production by microbial cells2016
- Author(s)
  Takashi Hirasawa and Hiroshi Shimizu
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume: 42 Pages: 133-146
- DOI
  10.1016/j.copbio.2016.04.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04576, KAKENHI-PROJECT-16K14881
[Journal Article] Combinatorial deletions of glgC and phaCE enhance ethanol production in Synechocystis sp. PCC 68032016
- Author(s)
  Katsunori Namakoshi, Tubasa Nakajima, Katsunori Yoshikawa, Yoshihiro Toya, Hiroshi Shimizu
- Journal Title
  
  Journal of Biotechnology
  
  Volume: 239 Pages: 13-19
- DOI
  10.1016/j.jbiotec.2016.09.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Metabolic flux analysis of Synechocystis sp. PCC6803 ΔnrtABCD mutant reveals a mechanism for metabolic adaptation to nitrogen-limited conditions2016
- Author(s)
  Tsubasa Nakajima, Katsunori Yoshikawa, Yoshihiro Toya, Fumio Matsuda, and Hiroshi Shimizu
- Journal Title
  
  Plant and Cell Physiology
  
  Volume: 58 Issue: 5 Pages: 537-545
- DOI
  10.1093/pcp/pcx047
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06559
[Journal Article] Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition2016
- Author(s)
 Yuta Matsushima, Takashi Hirasawa, Hiroshi Shimizu
- Journal Title
 
 J. Gen. Appl. Microbiol.
 
 Volume: 62 Issue: 1 Pages: 42-45
- DOI
 10.2323/jgam.62.42
- NAID
 130005127286
- ISSN
 0022-1260, 1349-8037
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-24246134
[Journal Article] Metabolomic analysis of acid stress response in Saccharomyces cerevisiae2015
- Author(s)
  Riyanto Heru Nugroho, Katsunori Yoshikawa, Hiroshi Shimizu
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 120 Issue: 4 Pages: 396-404
- DOI
  10.1016/j.jbiosc.2015.02.011
- NAID
  110010010221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] Phenotypic convergence in bacterial adaptive evolution to ethanol stress2015
- Author(s)
  Takaaki Horinouchi, Shingo Suzuki, Takashi Hirasawa, Naoaki Ono, Tetsuya Yomo, Hiroshi Shizmiu, Chikara Furusawa
- Journal Title
  
  BMC Evo. Biol.
  
  Volume: 15 Issue: 1 Pages: 180-180
- DOI
  10.1186/s12862-015-0454-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05746, KAKENHI-PROJECT-24246134, KAKENHI-PROJECT-26640135, KAKENHI-PROJECT-26290071
[Journal Article] 13C-based metabolic flux analysis of Saccharomyces cerevisiae with a reduced Crabtree effect2015
- Author(s)
  Shuichi Kajihata, Fumio Matsuda, Mika Yoshimi, Kenshi Hayakawa, Chikara Furusawa, Akihisa Kanda, Hiroshi Shimizu
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 120 Issue: 2 Pages: 140-144
- DOI
  10.1016/j.jbiosc.2014.12.014
- NAID
  210000005080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli2014
- Author(s)
  Kento Tokuyama, Satoshi Ohno, Katsunori Yoshikawa, Takashi Hirasawa, Shotaro Tanaka, Chikara Furusawa and Hiroshi Shimizu
- Journal Title
  
  Microbial Cell Factories
  
  Volume: 13 Issue: 1 Pages: 64-64
- DOI
  10.1186/1475-2859-13-64
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23680030, KAKENHI-PROJECT-24246134
[Journal Article] Enhanced acetic acid and succinic acid production under microaerobic conditions by Corynebacterium glutamicum harboring Escherichia coli transhydrogenase gene pntAB2014
- Author(s)
 Yuto Yamauchi, Takashi Hiraswa, Msato Nishii, Chikara Furuasawa, Hiroshi Shimizu
- Journal Title
 
 J. Gen. Appl. Microbiol.
 
 Volume: 60 Issue: 3 Pages: 112-118
- DOI
 10.2323/jgam.60.112
- NAID
 130004449385
- ISSN
 0022-1260, 1349-8037
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-24246134
[Journal Article] Metabolic engineering of Saccharomyces cerevisiae for improving succinic acid production based on metabolic profiling2014
- Author(s)
  Yuma Ito, Takashi Hirasawa, Hiroshi Shimizu
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] FastPros : screening of reaction knockout strategies for metabolic engineering2014
- Author(s)
  Satoshi Ohno, Chikara Furusawa and Hiroshi Shimizu
- Journal Title
  
  Bioinformatics
  
  Volume: 30(7) Issue: 7 Pages: 981-7
- DOI
  10.1093/bioinformatics/btt672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680030, KAKENHI-PROJECT-24246134, KAKENHI-PUBLICLY-25128715
[Journal Article] Development of an automated culture system for laboratory evolution2014
- Author(s)
  Takaaki Horinouchi, Teruaki Minamoto, Shingo Suzuki, Hiroshi Shimizu, Chikara Furusawa
- Journal Title
  
  Journal of Laborarory Automation
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] Addendum, Potential of a Saccharomyces cerevisiae recombinant strain lacking ethanol and glycerol biosynthesis pathways in efficient anaerobic bioproduction2014
- Author(s)
  Takashi Hirasawa, Yoshihiro Ida, Chikara Furusawa, Hiroshi Shimizu
- Journal Title
  
  Bioengineered
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] In silico screening of triple reaction knockout Escherichia coli strains for overproduction of useful metabolites2013
- Author(s)
  Satoshi Ohno, Chikara Furusawa, Hiroshi Shimizu
- Journal Title
  
  J. Biosci. Bioeng
  
  Volume: 115 Pages: 221-228
- NAID
  110009592575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions2013
- Author(s)
  Katsunori Yoshikawa
- Journal Title
  
  Biotechnology Journal
  
  Volume: 印刷中 Issue: 5 Pages: 571-580
- DOI
  10.1002/biot.201200235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23656526
[Journal Article] 代謝工学の創成と発展、-代謝解析とオミクス研究との融合2012
- Author(s)
  清水浩
- Journal Title
  
  生物工学会誌
  
  Volume: 90 Pages: 619-620
- NAID
  110009553229
- Data Source
  KAKENHI-PROJECT-24246134
[Journal Article] Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp2011
- Author(s)
  Katsunori Yoshikawa, Yuta Kojima, Tsubasa Nakajima, Chikara Furusawa, Takashi Hirasawa and Hiroshi Shimizu
- Journal Title
  
  PCC6803, Applied Microbiology and Biotechnology
  
  Volume: 92:2 Issue: 2 Pages: 347-358
- DOI
  10.1007/s00253-011-3559-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23656526
[Journal Article] Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress2010
- Author(s)
  Takaaki Horinouchi, Hiroshi Shimizu
- Journal Title
  
  BMC Genomics
  
  Volume: Vol.11 Pages: 579-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360401
[Journal Article] Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress2010
- Author(s)
  Takaaki Horinouchi, Kuniyasu Tamaoka, Chikara Furusawa, Naoaki Ono, Shingo Suzuki, Takashi Hirasawa, Tetsuya Yomo, Hiroshi Shimizu.
- Journal Title
  
  BMC Genomics
  
  Volume: 11 Issue: 1 Pages: 579-579
- DOI
  10.1186/1471-2164-11-579
- Data Source
  KAKENHI-PROJECT-21360401
[Journal Article] Dynamic change in promoter activation in lysine biosynthesis of Escherichia coli cell2008
- Author(s)
  J. Ou, H. Shimizu, ら7名
- Journal Title
  
  Molecular Bio Systems 4巻
  
  Pages: 128-134
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Dynamic change in promoter activation in lysine biosynthesis of Escherichia coli cell2008
- Author(s)
  J. Ou, H. Shimizuら7名
- Journal Title
  
  Molecular BioSystems 4巻
  
  Pages: 128-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Advanced Technology of Metabolomics and its Application, Chapter 14, Metabolic flux analysis based on metabolomics data2008
- Author(s)
  H., Shimizu, C., Furusawa, T., Shirai
- Journal Title
  
  CMC Publisher Inc
  
  Pages: 171-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Dynamic change in promoter activation in lysine biosynthesis of Escherichia coli cell2008
- Author(s)
  J., Cu, H. Shimizu, et. al.
- Journal Title
  
  Molecular BioSystems 4
  
  Pages: 128-134
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Identification of target genes for conferring ethanol stress-tolerance to yeast Saccharomyces cerevisiae based on DNA microarray data analysis2007
- Author(s)
  T., Hirasawa, H., Shimizu, et. al.
- Journal Title
  
  Journal of Biotechnology 131
  
  Pages: 33-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Extracting hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA micro array data using Self Organizing Map2007
- Author(s)
  G.Pandey, H.Shimizuら全8名
- Journal Title
  
  Applied Microbiology and Biotechnology (In press)(印刷中)
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Analysis of fluctuation in protein abundance without promoter regulation based on Eschrichia coli continuous culture2007
- Author(s)
  T. Yamada, H. Shimizuら6名
- Journal Title
  
  BioSystems 90巻
  
  Pages: 614-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Metabolic pathway rerouting through genomic data analysis for industrial application of Saccharomyces cerevisiae2007
- Author(s)
  S. Shioya, H. Shimizu, ら8名
- Journal Title
  
  Biochemical Engineering Journal 36巻
  
  Pages: 28-37
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis2007
- Author(s)
  T. Shirai, H. Shimizu, ら6名
- Journal Title
  
  Microbial Cell Factory 6巻
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Metabolic pathway rerouting through genomic data analysis for industrial application of Saccharomyces cerevisiae2007
- Author(s)
  S. Shioya, H. Shimizuら8名
- Journal Title
  
  Biochemical Engineering Journal 36巻
  
  Pages: 28-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis2007
- Author(s)
  T. Shirai, H. Shimizuら6名
- Journal Title
  
  Microbial Cell Factory 6巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Identification of target genes for conferring ethanol stress-tolerance to yeast Saccharomyces cerevisiae based on DNA microarray data analysis2007
- Author(s)
  T. Hirasawa, H. Shimizu, ら8名
- Journal Title
  
  Journal of Biotechnology 131巻
  
  Pages: 33-44
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Metabolic pathway rerouting through genomic data analysis for industrial application of Saccharomyces cerevisiae2007
- Author(s)
  S., Shioya, H., Shimizu, et. al.
- Journal Title
  
  Biochemical Engineering Journal 36(1)
  
  Pages: 28-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Extracting hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA micro array data using self organizing map: biosynthesis of amino acids2007
- Author(s)
  G. Pandey, H. Shimizuら8名
- Journal Title
  
  Applied Microbiology Biotechnology 75巻
  
  Pages: 415-426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Extracting hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA micro array data using self organizing map : biosynthesis of amino acids2007
- Author(s)
  G., Pandey, H., Shimizu
- Journal Title
  
  Applied Microbiology and Biotechnology 75
  
  Pages: 415-426
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Extracting hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA micro array data using self organizing map: biosynthesis of amino acids2007
- Author(s)
  G. Pandey, H. Shimizu, ら8名
- Journal Title
  
  Applied Microbiology Biotechnology 75巻
  
  Pages: 415-426
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Identification of target genes for conferring ethanol stress-tolerance to yeast Saccharomyces cerevisiae based on DNA microarray data analysis2007
- Author(s)
  T. Hirasawa, H. Shimizuら8名
- Journal Title
  
  Journal of Biotechnology 131巻
  
  Pages: 33-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Analysis of fluctuation in protein abundance without promoter regulation based on Eschrichia coli continuous culture2007
- Author(s)
  T., Yamada, H., Shimizu
- Journal Title
  
  BioSystems 90
  
  Pages: 614-622
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Metabolic pathway rerouting through genomic data analysis for industrial application of Saccharomyces cerevisiae2007
- Author(s)
  S.Shioya, H.Shimizuら全8名
- Journal Title
  
  Biochemical Engineering Journal (In press)(印刷中)
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis2007
- Author(s)
  T., Shirai, H., Shimizu, et. al.
- Journal Title
  
  Microbial Cell Factory 6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Analysis of fluctuation in protein abundance without promoter regulati on based on Eschrichia coli continuous culture2007
- Author(s)
  T. Yamada, H. Shimizu, ら6名
- Journal Title
  
  Bio Systems 90巻
  
  Pages: 614-622
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Precise metabolic flux analysis of coryneform bacteria with gas spectrometry -mass spectrometry and verification of nuclear magnetic resonance2006
- Author(s)
  T., Shirai, H., Shimizu, et. al.
- Journal Title
  
  Journal of Bioscience and Bioengineering 102(5)
  
  Pages: 413-424
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Comparison of transcriptional responses to osmotic stresses induced by NaCl and sorbitol additions in Saccharomyces cerevisiae using DNA microarray2006
- Author(s)
  H.Hirasawa, H.Shimizuら全8名
- Journal Title
  
  Journal of Bioscience and Bioengineering 102巻6号
  
  Pages: 568-571
- NAID
  110006196953
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Analysis of fluctuation in gene expression based on continuous culture system2006
- Author(s)
  T.Yamada, H.Shimizu et al.
- Journal Title
  
  Proceedings of The 2nd International Workshop on Biologically Inspired Approaches to Advanced Information Technology LNCS 3853
  
  Pages: 113-127
- Data Source
  KAKENHI-PROJECT-16650063
[Journal Article] Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray2006
- Author(s)
  H., Hirasawa, H., Shimizu, et. al.
- Journal Title
  
  Applied Microbiology and Biotechnology 70(3)
  
  Pages: 346-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray2006
- Author(s)
  H.Hirasawa, H.Shimizuら全9名
- Journal Title
  
  Applied Microbiology and Biotechnology 70巻3号
  
  Pages: 346-357
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Comparison of transcriptional responses to osmotic stresses induced by NaCI and sorbitol additions in Saccharomyces cerevisiae using DNAmicroarray2006
- Author(s)
  H., Hirasawa, H., Shimizu, et. al.
- Journal Title
  
  Journal of Bioscience and Bioengineering 102(6)
  
  Pages: 568-571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Precise metabolic flux analysis of coryneform bacteria with gas spectrometry-mass spectrometry and verification of nuclear magnetic resonance2006
- Author(s)
  T.Shirai, H.Shimizuら全7名
- Journal Title
  
  Journal of Bioscience and Bioengineering 102巻5号
  
  Pages: 413-424
- Data Source
  KAKENHI-PROJECT-18360395
[Journal Article] Dynamic Behavior of Cell Distribution in Continuous Culture of Escherichia coli2005
- Author(s)
  T.Yamdada, H.Shimizu et al.
- Journal Title
  
  ソフトウエアバイオロジー 4
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-16650063
[Journal Article] Dynamic Behavior of Cell Distribution in Continuous Culture of Escherichia coli2005
- Author(s)
  T.Yamdada, H.Shimizu et al.
- Journal Title
  
  ソフトウエアバイオロジー 4巻(印刷中)
- Data Source
  KAKENHI-PROJECT-16650063
[Journal Article] Analysis of Cell Population Dynamics in Continuous Culture of Escherichia coli2004
- Author(s)
  T.yamdada, H.Shimizu et al.
- Journal Title
  
  Proceedings of 10th The Asia Pacific Confederations on Chemical Engineering (APCChE04), Kitakyushu, 6 Pages, Oct 17-21(2004) (CD-ROM)
- NAID
  130005052895
- Data Source
  KAKENHI-PROJECT-16650063
[Journal Article] Analysis of Cell Population Dynamics in Continuous Culture of Escherichia coli2004
- Author(s)
  T.Yamdada, H.Shimizu et al.
- Journal Title
  
  Proceedings of 10th The Asia Pacific Confederation on Chemical Engineering (APCChE04), Kitakyushu, 6 pages, Oct 17-21(2004) (CD-ROM)
- NAID
  130005052895
- Data Source
  KAKENHI-PROJECT-16650063
[Journal Article] Enhanced kefiran production by mixed culture of Lactobacillus kefiranofaciens and Saccharomyces cerevisiae2003
- Author(s)
  B.Cheirsilp, H.Shimizu, S.Shioya
- Journal Title
  
  Journal of Biotechnology 100
  
  Pages: 45-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15360441
[Journal Article] Interactions between Lactobacillus kefiranofaciens and Saccharomyce scerevisiae in mixed culture of kefiran production2003
- Author(s)
  B.Cheirsilp, H.Shoji, H.Shimizu, S.Shioya
- Journal Title
  
  Journal of Bioscience and Bioengineering 96
  
  Pages: 278-284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15360441
[Journal Article] Interactions between Lactobacillus kefiranofaciens and Saccharomyce scerevisiae in mixed culture of kefiran production.2003
- Author(s)
  B.Cheirsilp, H.Shoji, H.Shimizu, S.Shioya
- Journal Title
  
  Journal of Bioscience and Bioengineering 96
  
  Pages: 278-284
- Data Source
  KAKENHI-PROJECT-15360441
[Patent] ホスホエノールピルビン酸カルボキシラーゼを活性化することができるポリペプチド2023
- Inventor(s)
  松村浩由、戸谷吉博、清水浩　他７名
- Industrial Property Rights Holder
  松村浩由、戸谷吉博、清水浩　他７名
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 計算機工学を基盤とするバイオテクノロジーの高度化2024
- Author(s)
  清水浩
- Organizer
  化学工学会バイオプロセス講演会「生物機能を利用したモノづくり」に貢献するプロセス強化
- Invited
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] マルチカラー光による大腸菌代謝経路のフラックス制御技術の開発2024
- Author(s)
  赤木駿斗、清水浩、戸谷吉博
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 大腸菌におけるメバロン酸生産のための光遺伝学技術を利用した代謝工学2024
- Author(s)
  櫻井翔太、清水浩、戸谷吉博
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] グリコールアルデヒドがシアノバクテリアの代謝に与える影響の解析2024
- Author(s)
  今田辰海，戸谷吉博，清水浩
- Organizer
  化学工学会第89年会
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] 機械学習を活用した酵素の分子認識特性の変換2023
- Author(s)
  二井手哲平、杉木創、森聖也、戸谷吉博、清水浩
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Metabolic Engineering Based on in Silico Design and Experimental Analysis for Bioproduction2023
- Author(s)
  Hiroshi Shimizu
- Organizer
  ASBA2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 光駆動プロトンポンプを利用した大腸菌の酸耐性の強化と有用物質生産への応用2023
- Author(s)
  小林祐摩、佐野海瑚人、弘埜陽子、松田史生、石井純、原清敬、清水浩、戸谷吉博
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 進化と構造の情報を組み込んだ酵素の耐熱化デザイン2023
- Author(s)
  宮脇佳汰、二井手哲平、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 光遺伝学による複数酵素を対象とした代謝フラックス抑制技術の開発2023
- Author(s)
  櫻井翔太、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] EL222-based optogenetic flux control on the glycolytic pathways in Escherichia coli2023
- Author(s)
  Hayto Akagi、 Hiroshi Shimizu、 Yoshihiro Toya
- Organizer
  Metabolic Engineering 15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Light-driven ATP regeneration for enhancing 3-hydroxypropionic acid and isoprenol productions in Escherichia coli2023
- Author(s)
  Yoshihiro Toya、Mikoto Sano、Ryo Tanaka、 Kentaro Kamata、Fumio Matsuda、Jun Ishii、 Yoko Hirono-Hara、 Kiyotaka Y. Hara、 Hiroshi Shimizu
- Organizer
  Metabolic Engineering 15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] モデル基盤代謝デザインと指向性進化による微生物創製2023
- Author(s)
  清水浩、戸谷吉博、古澤力、芝井厚、堀之内貴明、鈴木宏明、徳山健斗、二井手哲平
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] エレメンタリーモード解析による非酸化的解糖経路を導入したブチロラクタム生産大腸菌の代謝デザイン2023
- Author(s)
  三吉健太、二井手哲平、戸谷吉博、清水浩
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 酵素の基質特異性決定残基の同定におけるロジステック回帰モデルの有用性2023
- Author(s)
  二井手哲平、杉木創、森聖也、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Optimal production of mevalonate by modification of ribosome-binding sequences of Escherichia coli chromosome2023
- Author(s)
  Shogo Sawada、Yoshihiro Toya、Hiroshi Shimizu
- Organizer
  Metabolic Engineering 15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] モデルベース指向性進化による中枢代謝の各経路における律速の解放2023
- Author(s)
  戸谷吉博、三吉健太、川本優一、芝井厚、古澤力、清水浩
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] リボソーム結合配列の改変による幅広い解糖系のフラックス比を持つ大腸菌ライブラリの構築2023
- Author(s)
  下谷朋輝、澤田将吾、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 大腸菌におけるギ酸資化経路を稼働させるための培養条件の探索2023
- Author(s)
  巽慶太郎、小林祐摩、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Machine learning-guided cofactor specificity conversion of a malic enzyme using sequence datasets divided by catalytic properties2023
- Author(s)
  Teppei Niide、 Sou Sugiki、 Yoshihiro Toya、 Hiroshi Shimizu
- Organizer
  Metabolic Engineering 15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 非酸化的解糖経路を導入した大腸菌によるブチロラクタム生産のための代謝経路改変2023
- Author(s)
  三吉健太、一色衣香、二井手哲平、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 光遺伝学技術を利用した代謝フラックス制御とその応用2023
- Author(s)
  戸谷吉博、赤木駿斗、櫻井翔太、川西寿和、塚本雅士、清水浩
- Organizer
  化学工学会第54回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 光遺伝学代謝フラックス制御を利用した大腸菌の1,3-プロパンジオール生産2023
- Author(s)
  川西寿和、櫻井翔太、清水浩、戸谷吉博
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 機械学習を用いた代謝酵素の基質特異性決定残基の推定と変換2023
- Author(s)
  森聖也、二井手哲平、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] マルチカラー光による大腸菌の代謝フラックス分布の光遺伝学的制御2023
- Author(s)
  赤木駿斗、清水浩、戸谷吉博
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Metabolic design of butyrolactam-producing Escherichia coli introducing non-oxidative glycolysis by elementary mode analysis2023
- Author(s)
  Kenta Miyoshi、 Teppei Niide、 Yoshihiro Toya、 Hiroshi Shimizu
- Organizer
  Metabolic Engineering 15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 蛍光タンパク質センサを利用した大腸菌の新規NADPH再生反応の同定2023
- Author(s)
  上野航一郎、澤田将吾、石橋真衣、神田義貴、戸谷吉博、清水浩
- Organizer
  第75回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Effect of fluctuating light condition on photosynthesis and central carbon metabolism in Synechosystis sp. PCC 68032022
- Author(s)
  Tatsumi Imada, Chiaki Yamamoto, Yoshihiro Toya, and Hiroshi Shimizu
- Organizer
  International Symposium on Photosynthesis and Chloroplast Regulation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] マイクロドロップレットを用いた大腸菌指向進化実験のとりくみ2022
- Author(s)
  佐藤玲子、大竹理寛、高昱偲、戸谷吉博、清水浩、鈴木宏明
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 指向性進化を目的としたマイクロ流路細胞培養システムの開発2022
- Author(s)
  大竹理寛、佐藤玲子、戸谷吉博、清水浩、鈴木宏明
- Organizer
  日本機械学会2022年度年次大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] シアノバクテリアにおけるEntner-Doudoroff経路の生理学的役割2022
- Author(s)
  今田辰海、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] ロドプシンによる光駆動プロトンポンプが大腸菌の弱酸耐性に及ぼす影響2022
- Author(s)
  小林祐摩、佐野海瑚人、弘埜陽子、松田史生、石井純、原清敬、戸谷吉博、清水浩
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] シアノバクテリアにおけるエントナードウドロフ経路の生理学的影響の解析2022
- Author(s)
  今田辰海，戸谷吉博，清水浩
- Organizer
  第63回日本植物生理学会
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] 微生物共培養のための精製タグ付きタンパク質を利用した13C代謝フラックス比解析技術の開発2022
- Author(s)
  川本優一、二井手哲平、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] In silico and Experimental Metabolic Flux Analyses and their Applications to Fermentation Processes2022
- Author(s)
  Hiroshi Shimizu
- Organizer
  2022 Agricultural Biotechnology Symposium, Metabolomics for Food and Human Health, Center for Food and Bioconvergence,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 異なる炭素源を消費する2種類の大腸菌株を用いた共培養によるイソプレノール生産2022
- Author(s)
  村上茉奈美、川井隆太郎、三吉健太、芝井厚、前田智也、堀之内貴明、古澤力、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 非酸化的解糖経路の有望な目的化合物の検討とin silico代謝デザイン2022
- Author(s)
  三吉健太、一色衣香、二井手哲平、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 微生物共培養のための精製タンパク質を利用した13C代謝フラックス比解析技術の開発2022
- Author(s)
  川本優一、清水浩、戸谷吉博
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] マルチカラー光による代謝経路のフラックス制御に向けた検討2022
- Author(s)
  赤木駿斗、清水浩、戸谷吉博
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] In silico代謝デザインプラットフォームと代謝フラックス解析による微生物発酵の育種とプロセス開発の高度化2022
- Author(s)
  清水浩
- Organizer
  生物工学会中部支部第9回CHUBU懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 人工的な相利共生関係を利用した指向性進化による有用物質生産菌の開発2022
- Author(s)
  川井隆太郎、戸谷吉博、清水浩
- Organizer
  化学工学会第53回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] アンチセンスRNAを利用した光照射による代謝フラックス制御技術の開発2022
- Author(s)
  櫻井翔太、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 青色光応答タンパク質を利用した中枢代謝フラックスの制御技術の開発2022
- Author(s)
  赤木駿斗、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 大腸菌における非酸化的解糖系の機能評価と有用物質生産への応用可能性の検討2022
- Author(s)
  三吉健太、川井隆太郎、二井手哲平、戸谷吉博、清水浩
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] CO2排出を抑制した物質生産に向けた大腸菌における逆グリオキシル酸経路の利用2022
- Author(s)
  田中恒作、戸谷吉博、清水浩
- Organizer
  化学工学会第53回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 大腸菌の染色体上リボゾーム結合部位改変を利用した中枢炭素代謝フラックスの精密制御2022
- Author(s)
  澤田将吾、松田史生、戸谷吉博、清水浩
- Organizer
  化学工学会第53回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] In silico and Experimental Metabolic Flux Analyses and their Applications to Fermentation Processes2022
- Author(s)
  Hiroshi Shimizu
- Organizer
  International Symposium on Photosynthesis and Chloroplast Regulation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] 共培養代謝工学のための経路分断方法の検討2022
- Author(s)
  多田一紀、清水浩、戸谷吉博
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 大腸菌におけるロドプシンの光駆動プロトンポンプが弱酸耐性に及ぼす影響2022
- Author(s)
  小林祐摩、佐野海瑚人、弘埜陽子、松田史生、石井純、原清敬、戸谷吉博、清水浩
- Organizer
  第74回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 共培養チロシン生産に適した代謝改変の検討2022
- Author(s)
  多田一紀、戸谷吉博、清水浩
- Organizer
  化学工学会第53回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] mBFPセンサーを使った栄養飢餓大腸菌における細胞内NADPHレベルの摂動解析2021
- Author(s)
  上野航一郎、戸谷吉博、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] FBA シミュレーションによるシアノバクテリアにおける PSI/PSII励起比と光合成電子伝達フラックスの関係ならびに NDH-1 の機能解析2021
- Author(s)
  豊島正和、山本千晶、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  第6回光合成細菌ワークショップ
- Invited
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 逆グリオキシル酸経路を導入した大腸菌の開発と代謝評価2021
- Author(s)
  田中恒作、戸谷吉博、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 大腸菌染色体上のリボソーム結合配列改変による中枢代謝フラックスの調節2021
- Author(s)
  澤田将吾、松田史生、戸谷吉博、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 機械学習を利用した代謝酵素の補酵素特異性の設計と活性測定による検証2021
- Author(s)
  杉木創、二井手哲平、戸谷吉博、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 動的代謝モデルを用いたシアノバクテリアのカルビン回路における制御機構の解析2021
- Author(s)
  田島遼太郎，池原万由，戸谷吉博，清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] メバロン酸取り込み能力が強化された進化株のゲノム変異解析2021
- Author(s)
  村上茉奈美、川井隆太郎、前田智也、堀之内貴明、古澤力、戸谷吉博、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] NAD(P)H dehydrogenase deletion enhances accumulation of polyhydroxybutyrate in Synechocystis sp. PCC 68032021
- Author(s)
  Masakazu Yajima, Masakazu Toyoshima, Yoshihiro Toya, Hiroshi Shimizu
- Organizer
  第62回日本植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 環境調和型ものづくり-発酵技術の高度化-2021
- Author(s)
  清水浩
- Organizer
  第73回日本生物工学会大会　ランチタイムセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] モデル基盤代謝デザインと指向性進化による高効率細胞工場の創製2021
- Author(s)
  清水浩
- Organizer
  日本化学会第101春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 指向性進化を目的とした細胞長期培養マイクロデバイスの開発2021
- Author(s)
  大竹理寛、佐藤玲子、戸谷吉博、清水浩、鈴木宏明
- Organizer
  日本機械学会第12回マイクロ・ナノ工学シンポジウム
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 代謝シミュレーションと指向性進化に基づく有用物質生産微生物の開発2021
- Author(s)
  戸谷吉博，川井隆太郎，三吉健太，村上茉奈美，一色衣香，堀之内貴明，前田智也，古澤力，清水浩
- Organizer
  化学工学会第52回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 青色光による遺伝子発現制御系を用いた大腸菌代謝制御の検討2021
- Author(s)
  赤木駿斗、塚本雅士、戸谷吉博、清水浩
- Organizer
  化学工学会第52回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] Synechocystis sp. PCC 6803のΔndhD1/D2株を用いたレドックスバランス感知フィコビリソーム分解制御機構の解析2021
- Author(s)
  豊島正和、阪田真澄、山本千晶、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  第62回日本植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シアノバクテリアの代謝工学2021
- Author(s)
  清水浩，戸谷吉博，豊島正和，山本千晶
- Organizer
  化学工学会第52回秋季大会
- Data Source
  KAKENHI-PROJECT-21K19825
[Presentation] 連続培養を用いた指向性進化実験による大腸菌のメバロン酸取り込み能力の強化2021
- Author(s)
  村上茉奈美、川井隆太郎、前田智也、堀之内貴明、古澤力、戸谷吉博、清水浩
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 機械学習を用いたリンゴ酸酵素の補酵素特異性の予測2021
- Author(s)
  杉木創、二井手哲平、戸谷吉博、清水浩
- Organizer
  化学工学会第52回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 光合成生物のシステムバイオロジー2021
- Author(s)
  清水浩
- Organizer
  第62回日本植物生理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 動的代謝モデルを用いたカルビン回路の代謝制御機構の解析2021
- Author(s)
  田島遼太郎、池原万由、戸谷吉博、清水浩
- Organizer
  第62回日本植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 大腸菌生体内における非酸化的解糖系経路の代謝フラックスの評価2021
- Author(s)
  三吉健太、川井隆太郎、二井手哲平、戸谷吉博、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 蛍光タンパク質を利用した共培養のための菌体比率制御技術の開発2021
- Author(s)
  楠田みのり、戸谷吉博、清水浩
- Organizer
  化学工学会第86年会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 目的物質生産フラックス強化のためのシミュレーションに基づく増殖連動型の代謝設計2021
- Author(s)
  戸谷吉博、一色衣香、施欣馳、清水浩
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] In silico代謝デザインに基づく非酸化的解糖系依存の大腸菌株の創出2020
- Author(s)
  三吉健太、川井隆太郎、堀之内貴明、戸谷吉博、清水浩
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 13C-metabolic flux analysis reveals photosynthetic cofactor production rates in cyanobacteria2020
- Author(s)
  Chiaki Yamamoto、 Sayaka Kitamura、Masakazu Toyoshima、Yoshihiro Toya、 Hiroshi Shimizu
- Organizer
  上海交通大学学術交流セミナー
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 13C代謝フラックス解析を用いたシアノバクテリアにおける光化学系からのATP/NADPH生産速度の推定2020
- Author(s)
  山本千晶、北村さや香、豊島正和、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  日本植物生理学会2020年度大阪年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 実験室進化実験による大腸菌の非酸化的解糖経路のフラックス増強2020
- Author(s)
  三吉健太、川井隆太郎、堀之内貴明、前田智也、古澤力、戸谷吉博、清水浩
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 異なる波長の光照射下におけるシアノバクテリアの光合成と代謝のシミュレーション予測による適応機構の解析2020
- Author(s)
  豊島正和、山本千晶、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  日本植物学会第84回大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 光誘導スイッチを利用した代謝フラックスの動的な調節技術の開発2020
- Author(s)
  塚本雅士、戸谷吉博、清水浩
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 微生物物質生産の代謝デザインと細胞性能評価2020
- Author(s)
  清水浩　戸谷吉博
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 化学量論モデルを用いたFBAシミュレーションによるシアノバクテリアの光合成電子伝達の解析2020
- Author(s)
  豊島正和、山本千晶、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  第5回光合成細菌ワークショップ
- Invited
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝モデルを利用した指向性進化による大腸菌イソプレノール合成のボトルネック解消2020
- Author(s)
  川井隆太郎、三吉健太、堀之内貴明、前田智也、古澤力、戸谷吉博、清水浩
- Organizer
  日本生物工学会【関西支部】2020年度学生オンライン発表会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 相利共生関係を利用した増殖連動型の有用物質生産株の代謝設計2020
- Author(s)
  川井隆太郎、戸谷吉博、清水浩
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] FBAシミュレーションによる異なる波長の光照射下におけるSynechocystis sp. PCC 6803の光合成電子伝達経路の選択的使用の解明2020
- Author(s)
  豊島正和、山本千晶、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  日本植物生理学会2020年度大阪年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シアノバクテリアのカルビン回路の反応速度論モデルの開発2020
- Author(s)
  田島遼太郎、池原万由、戸谷吉博、清水浩
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 試験管内反応系を利用した代謝経路の律速段階の同定2020
- Author(s)
  北村さや香、戸谷吉博、清水浩
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] 13C代謝フラックス解析によるシアノバクテリアにおける光化学反応の補酵素生産速度の推定2019
- Author(s)
  山本千晶、北村さや香、豊島正和、戸谷吉博、清水浩
- Organizer
  令和元年度秋季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] In silico Design of Metabolic Pathways and Adaptive Laboratory Evolution for Improvement of Valuable Compounds Production2019
- Author(s)
  Shimizu Hiroshi
- Organizer
  2019 KSBB Sprilng Meeting and International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00839
[Presentation] FBAシミュレーションによる異なるPSI/PSII励起比におけるシアノバクテリアの光合成電子伝達の解析2019
- Author(s)
  豊島正和、山本千晶、戸谷吉博、清水浩
- Organizer
  2019年度ラン藻ゲノム交流会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Metabolic Engineering to Create Microbial Cell Factories2019
- Author(s)
  Shimizu Hiroshi
- Organizer
  The 21st Academic Exchange Seminar Between Shanghai Jiao Tong University And Osaka University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] FBAによるシアノバクテリアの光合成電子伝達フラックス状態の解析2019
- Author(s)
  豊島正和、山本千晶、植野嘉文、戸谷吉博、秋本誠志、清水浩
- Organizer
  令和元年度秋季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] QconCAT法を用いたシアノバクテリア光合成装置の絶対定量に関する研究2019
- Author(s)
  豊島正和、大西一輝、阪田真澄、戸谷吉博、清水浩
- Organizer
  新光合成、光合成若手の会ジョイント若手ワークショップ
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] FBAシミュレーションによる単波長光照射下におけるシアノバクテリアの光合成電子伝達経路のフラックス状態の解析2019
- Author(s)
  豊島正和、山本千晶、戸谷吉博、清水浩
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 異なる波長の光照射下におけるSynechocystis sp. PCC 6803の網羅的定量プロテオーム解析2019
- Author(s)
  豊島正和、阪田真澄、戸谷吉博、松田史生、清水浩
- Organizer
  第60回植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 異なる波長の光照射下におけるシアノバクテリアの中心代謝の13C代謝フラックス解析2019
- Author(s)
  山本千晶、北村さやか、豊島正和、戸谷吉博、清水浩
- Organizer
  第61回植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 大腸菌の共培養によるイソプレノール合成経路のボトルネックの解消2019
- Author(s)
  川井隆太郎、戸谷吉博、清水浩
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] プロトン駆動力による細胞内代謝制御2019
- Author(s)
  清水浩
- Organizer
  令和元年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 異なるPSI/PSII励起比における光合成電子伝達並びに呼吸鎖のフラックスバランス解析2019
- Author(s)
  豊島正和、戸谷吉博、清水浩
- Organizer
  令和元年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Metabolic Engineering of Synechocystis sp. PCC68032019
- Author(s)
  Shimizu Hiroshi、Toyoshima Masakazu、Toya Yoshihiro、Matsuda Fumio
- Organizer
  APCChE 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 異なる波長の光照射下におけるSynechocystis sp. PCC 6803の網羅的定量プロテオームと絶対定量2019
- Author(s)
  豊島正和、阪田真澄、大西一輝、戸谷吉博、松田史生、清水浩
- Organizer
  藍藻の分子生物学2019
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 異なる波長の光照射下におけるシアノバクテリアの中心代謝の13C代謝フラックス解析2019
- Author(s)
  山本千晶、北村さやか、豊島正和、戸谷吉博、清水浩
- Organizer
  令和元年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] FBA simulation of photosynthetic electron flow of Synechocystis sp. PCC 6803 under different spectral light condition2019
- Author(s)
  Toyoshima Masakazu、Yamamoto Chiaki 、Ueno Yoshifumi、Toya Yoshihiro 、Akimoto Seiji,、Shimizu Hiroshi
- Organizer
  日米二国間セミナー
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] in silico analysis and design of photosynthesis and metabolic pathways of Synechocystis sp. PCC68032019
- Author(s)
  Shimizu Hiroshi
- Organizer
  日米二国間セミナー
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] FBAによる単波長光照射下におけるシアノバクテリアの光合成電子伝達と代謝のシミュレーション2019
- Author(s)
  豊島正和、戸谷吉博、清水浩
- Organizer
  第10回日本光合成学会年会およびシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Integration of in silico Genetic Modification Design and Adaptive Laboratory Evolution to Increase in Productivity of Target Compounds2019
- Author(s)
  Shimizu Hiroshi
- Organizer
  International Conference on Metabolic Science 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05626
[Presentation] In silico Metabolic Pathway Design and Experimental Flux Analysis for Creation of Microbial Cell Factory2019
- Author(s)
  Shimizu Hiroshi
- Organizer
  KMB 2019 46th Annual Meeting & International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00839
[Presentation] 13C代謝フラックス解析に基づくシアノバクテリアの単波長光照射下に対する応答解析2019
- Author(s)
  山本千晶、北村さや香、豊島正和、戸谷吉博、清水浩
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] フェノールが大腸菌の中枢代謝に及ぼす影響の解析2018
- Author(s)
  北村さや香、戸谷吉博、清水浩
- Organizer
  第70回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 様々な波長の光照射下におけるシアノバクテリアの解析2018
- Author(s)
  豊島正和、阪田真澄、戸谷吉博、松田史生、清水浩
- Organizer
  第70回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 動的代謝モデルアンサンブルを用いたエタノール生産シアノバクテリアの代謝工学2018
- Author(s)
  西口大貴、永井暉、松田史生、清水浩
- Organizer
  第70回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Expanding the space of actual metabolic network in Escherichia coli by adaptive laboratory evolution2018
- Author(s)
  Tokuyama Kento、Toya Yoshihiro、 Horinouchi Takaaki,、Furusawa Chikara、Matsuda Fumio、Shimizu Hiroshi
- Organizer
  Metabolic Engineering 12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] シアノバクテリアの代謝モデルを利用した動的解析に向けて2018
- Author(s)
  戸谷吉博、豊島正和、清水浩
- Organizer
  平成30年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 13C-Metabolic flux analysis of the central carbon metabolism in three cancer cell lines2018
- Author(s)
  Uehara Hikaru,、Araki Chie、Maeda Kousuke、Okahashi Nobuyuki、Matsuda Fumio、Shimizu Hiroshi
- Organizer
  YABEC2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19012
[Presentation] 13C代謝フラックス解析を用いたSynechocystis sp. PCC 6803のndhF遺伝子破壊株におけるNADPH消費機構の寄与率の解明2018
- Author(s)
  和田圭介、戸谷吉博、松田史生、清水浩
- Organizer
  第59回日本植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Rational metabolic engineering of central metabolism in cyanobacteria using kinetic model ensemble2018
- Author(s)
  Nishiguchi Hiroki、Nagai Hikaru、Matsuda Fumio、Shimizu Hiroshi
- Organizer
  International Symposium on Photosynthesis and Chloroplast Biogenesis 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 安定同位体非定常の13C代謝フラックス解析およびプロテオーム解析によるn-ブタノールを生産するSynechococcus elongatus PCC 7942の代謝状態の推定2018
- Author(s)
  和田圭介、植林希代加、戸谷吉博、傳寶雄大、Putri Sastia、松田史生、福崎英一郎、James C Liao、清水浩
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Target phosphoproteome analysis of Synchocystis sp PCC 6803 using nano liquid chromatography- triple quadrupole mass spectrometry2018
- Author(s)
  Tokumaru Yuma、Toyoshima Masakazu、Matsuda Fumio、Shimizu Hiroshi
- Organizer
  International Symposium on Photosynthesis and Chloroplast Biogenesis 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] FBAを用いた様々な波長の光照射下におけるSynechocystis sp. PCC 6803の野生株とNDH-1欠損株の代謝シミュレーション2018
- Author(s)
  豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  平成30年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] FBAシミュレーションによる単波長光照射下におけるPSI/PSII励起比とサイクリック電子伝達の解析2018
- Author(s)
  豊島正和、戸谷吉博、清水浩
- Organizer
  平成30年度秋季領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝工学に基づく大腸菌フェノール生産株の育種2018
- Author(s)
  北村さや香, 戸谷吉博, 清水浩
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] Target phosphoproteome analysis of Synchocystis sp PCC 6803 using nano liquid chromatography- triple quadrupole mass spectrometry2018
- Author(s)
  Tokumaru Yuma、Toyoshima Masakazu、Matsuda Fumio、Shimizu Hiroshi
- Organizer
  13th KAIST-OSAKA U Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Dynamic modeling of central metabolism in cyanobacteria for improving ethanol production2018
- Author(s)
  Nishiguchi Hiroki、Nagai Hikaru、Matsuda Fumio、Shimizu Hiroshi
- Organizer
  13th KAIST-OSAKA U Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] FBAを用いた様々な波長の光条件下におけるSynechocystis sp. PCC 6803の代謝シミュレーション2018
- Author(s)
  豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  第59回日本植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 増殖連動型物質生産のin silico解析における反応律速点の同定法の開発と実験検証2018
- Author(s)
  清水浩、徳山健斗、戸谷吉博、松田史生
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] Systems Biology and Metabolic Engineering of Photosynthetic Organisms2018
- Author(s)
  Shimizu Hiroshi
- Organizer
  International Symposium on Photosynthesis and Chloroplast Biogenesis 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] プロトン駆動力による細胞内代謝制御2018
- Author(s)
  清水浩
- Organizer
  平成30年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 四重極タンデム質量分析装置を用いたSynechocystis sp. PCC 6803のターゲットリン酸化プロテオーム解析2018
- Author(s)
  徳丸雄磨・豊島正和、松田史生、清水浩
- Organizer
  第59回日本植物生理学会年会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 様々な波長の光照射下のSynechocystis sp. PCC 6803 の野生株とNDH-1欠損株の生育を代謝シミュレーションする2018
- Author(s)
  豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  第9回日本光合成学会年会およびシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 適応進化実験によるシアノバクテリア強光耐性株の獲得とその解析2018
- Author(s)
  吉川勝徳、小川健一、戸谷吉博、秋本誠志、松田史生、清水浩
- Organizer
  第9回日本光合成学会年会およびシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝工学による光合成の統合解析と工学応用2018
- Author(s)
  清水浩
- Organizer
  第70回日本生物工学会大会　シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] クラミドモナス光化学系の定量プロテオミクス法の開発2018
- Author(s)
  大西一輝、徳丸雄磨、得津隆太郎、皆川純、豊島正和、松田史生、清水浩
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] がん種の異なる細胞間での中心代謝における13C代謝フラックス解析2018
- Author(s)
  上原ひかる、荒木千絵、前田昂亮、岡橋伸幸、松田史生、高橋智聡、清水浩
- Organizer
  第70回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-17K19012
[Presentation] 計算機工学に基づく代謝設計とその有効性の実証に関する研究2018
- Author(s)
  清水浩
- Organizer
  第70回日本生物工学会大会　生物工学功績賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 光量変化に対するシアノバクテリア代謝応答の解析2018
- Author(s)
  丸山正晴、西口大貴、豊島正和、松田史生、清水浩
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 計算機工学に基づく代謝設計とその有効性の実証に関する研究2018
- Author(s)
  清水浩
- Organizer
  第70回日本生物工学会大会　生物工学功績賞受賞講演
- Invited
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] クラミドモナス光化学系の定量プロテオーム解析とQconCAT法による絶対定量2018
- Author(s)
  大西一輝、徳丸雄磨、得津隆太郎、皆川純、豊島正和、松田史生、清水浩
- Organizer
  平成30年度春季新光合成領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シアノバクテリア中心炭素代謝における光量変化時の短期応答の解析2018
- Author(s)
  丸山正晴、西口大貴、豊島正和、松田史生、清水浩
- Organizer
  第70回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シアノバクテリアのゲノムスケール代謝モデルを用いたFBAシミュレーションによる解析2018
- Author(s)
  豊島正和、戸谷吉博、清水浩
- Organizer
  第5回分子珪藻研究会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] クラミドモナス光化学系の定量プロテオミクス法の検討と利用2018
- Author(s)
  大西一輝, 徳丸雄磨, 得津隆太郎, 皆川純, 豊島正和, 松田史生, 清水浩
- Organizer
  第9回日本光合成学会年会およびシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 微生物バイオプロセスにおける計測と育種・プロセス開発への展開2018
- Author(s)
  清水浩
- Organizer
  日本生物工学会バイオ計測サイエンス研究部会第一回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] Relationship between PSI/PSII excitation ratio and photosynthetic electron transport of Synechocystis sp. PCC 6803 by FBA simulation2018
- Author(s)
  Toyoshima Masakazu、Toya Yoshihiro、Shimizu Hiroshi
- Organizer
  International Symposium on Photosynthesis and Chloroplast Biogenesis 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] QconCAT法を用いたシアノバクテリア光化学装置の定量プロテオミクス2017
- Author(s)
  徳丸雄磨、植林希代加、徳山健斗、和田圭介、松田史生、清水浩
- Organizer
  第65回質量分析総合討論会 2017 つくば
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 光合成微生物の代謝モデルの開発と応用2017
- Author(s)
  豊島正和、戸谷吉博、吉川勝徳、松田史生、清水浩
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シアノバクテリアSynechocystis sp. PCC 6803の光化学反応を精緻化したゲノムスケールモデルを用いた様々な光条件における代謝シミュレーション2017
- Author(s)
  豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  第69回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] nanoLC-MSを用いた網羅的定量プロテオーム解析に向けたタンパク質抽出方法の検討2017
- Author(s)
  豊島正和、阪田真澄、大西一輝、徳丸雄磨、松田史生、清水浩
- Organizer
  科研費新学術領域研究平成29年度秋期領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Synechocystis sp. PCC 6803の精緻化した代謝モデルを用いた光合成研究への応用2017
- Author(s)
  豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  第10回日本光合成学会年会およびシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 実験室進化実験に基づく大腸菌の高コハク酸生産に有効な変異同定2017
- Author(s)
  徳山健斗,　戸谷吉博, 堀之内貴明, 古澤力, 清水浩,
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 代謝物濃度絶対定量値を用いたエタノール生産シアノバクテリア代謝律速点の解析2017
- Author(s)
  西口大貴、永井暉、松田史生、清水浩
- Organizer
  第69回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シグマ因子SigEによるシアノバクテリア代謝制御の定量プロテオーム解析2017
- Author(s)
  徳丸雄磨、植林希代加、小山内崇、松田史生、清水浩
- Organizer
  第69回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝物絶対定量データを用いたシアノバクテリア動的代謝モデル構築2017
- Author(s)
  西口大貴、永井暉、松田史生、清水浩
- Organizer
  第１１回メタボロームシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シアノバクテリアのシステムバイオロジーによる統合理解と工学応用2017
- Author(s)
  清水浩、豊島正和、戸谷吉博、松田史生
- Organizer
  藍藻の分子生物学2017
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝物濃度の絶対定量値を用いたエタノール生産シアノバクテリア代謝律速点の解析2017
- Author(s)
  西口大貴, 永井暉, 松田史生, 清水浩
- Organizer
  第58回日本植物生理学会年会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 13C代謝フラックス解析による細胞の生理状態の理解と工学応用2017
- Author(s)
  清水浩, 松田史生, 戸谷吉博, 岡橋伸幸, 前田昂亮
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] シアノバクテリアのSigEの代謝制御解明に向けた定量プロテオーム解析 "2017
- Author(s)
  徳丸雄磨、植林希代加、豊島正和、小山内崇、松田史生、清水浩
- Organizer
  科研費新学術領域研究平成29年度秋期領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Chlamydomonas reinhardtiiの定量プロテオミクスのための膜タンパク質可溶化手法の検討2017
- Author(s)
  大西一輝、徳丸雄磨、阪田真澄、豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  科研費新学術領域研究平成29年度秋期領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 13C代謝フラックス解析およびプロテオーム解析を用いたn-ブタノール生産シアノバクテリア株の代謝解析2017
- Author(s)
  和田圭介、植林希代加、戸谷吉博、傳寶雄大、Putri Sastia、松田史生、福崎英一郎、Liao James、清水浩
- Organizer
  第69回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝物濃度絶対定量値を用いたエタノール生産シアノバクテリア代謝律速点の解析2017
- Author(s)
  西口大貴、永井暉、松田史生、清水浩
- Organizer
  第65回質量分析総合討論会 2017 つくば
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Synechocystis sp. PCC 6803の中心代謝経路と光化学系の制御メカニズムの解析2017
- Author(s)
  和田圭介、戸谷吉博、吉川勝徳、松田史生、清水浩
- Organizer
  化学工学会第49回秋季大会
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 光合成微生物の化学量論モデルを利用したシミュレーションとその応用2017
- Author(s)
  戸谷吉博，吉川勝徳，松田史生，清水浩
- Organizer
  第58回日本植物生理学会年会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Quantitative proteome analysis of microalgae under high light stress2017
- Author(s)
  Masakazu Toyoshima, Masumi Sakata, Kazuki Ohnishi, Yuma Tokumaru, Fumio Matsuda, Hiroshi Shimizu
- Organizer
  I-Bios2017
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] nanoLC-MSを用いたシアノバクテリアの網羅的定量プロテオーム解析2017
- Author(s)
  豊島正和、阪田真澄、松田史生、清水浩
- Organizer
  藍藻の分子生物学2017
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 光量条件がシアノバクテリアの代謝フラックスに及ぼす影響の解析2017
- Author(s)
  上田賢太朗、仲嶋翼、吉川勝徳、戸谷吉博、松田史生、清水浩
- Organizer
  第9回日本光合成学会年会およびシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] シグマ因子SigEによるSynechocystis sp. PCC 6803のプロテオームの制御2017
- Author(s)
  徳丸雄磨,　植林希代加,　小山内崇,　松田史生,　清水浩
- Organizer
  第58回日本植物生理学会年会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Synechocystis sp. PCC 6803における多様な波長の光環境下での代謝シミュレーション2017
- Author(s)
  豊島正和、戸谷吉博、松田史生、清水浩
- Organizer
  科研費新学術領域研究平成29年度秋期領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 定常期における大腸菌メバロン酸生産株の13C代謝フラックス解析2017
- Author(s)
  増田亜美、徳山健斗、戸谷吉博、清水浩
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都江東区）
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] ブタノール生産シアノバクテリアの代謝解析2017
- Author(s)
  和田圭介、植林希代加、戸谷吉博、傳寶雄大、Putri Sastia 、松田史生、福崎英一郎、 Liao James C ,、清水浩
- Organizer
  科研費新学術領域研究平成29年度秋期領域会議
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 光量変化に対するシアノバクテリア代謝適応機構の解析2017
- Author(s)
  丸山正晴・西口大貴、松田史生、清水浩
- Organizer
  第１１回メタボロームシンポジウム
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] Integration of in silico design and experimental evaluation of metabolic pathways for creation of microbial cell factories,2016
- Author(s)
  Hiroshi Shimizu
- Organizer
  International Conference on the Metabolic Science,
- Place of Presentation
  Nanjiao Hotel, Shanghai China,
- Year and Date
  2016-10-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] In silico代謝デザインと13C代謝フラックス解析による微生物細胞工場の創製2016
- Author(s)
  清水浩
- Organizer
  第６回合成生物工学シンポジウム
- Place of Presentation
  神戸大学百年記念館六甲ホール（兵庫県神戸市灘区）
- Invited
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] メバロン酸生産大腸菌の細胞内代謝状態の定量的な評価2016
- Author(s)
  永井暉, 戸谷吉博, 松田史生, 清水浩
- Organizer
  第68回日本生物工学会大会（2016）
- Place of Presentation
  冨山国際会議場　ANAクラウンプラザホテル富山（富山県富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 13C-metabolic flux analysis for rational design of metabolic pathway modification of the industrially useful microorganisms2016
- Author(s)
  Hiroshi Shimizu
- Organizer
  The 13th International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  East Lake Hotel, Wuhan, China
- Year and Date
  2016-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] #in silico#代謝設計と実験室進化実験の統合によるコハク酸高生産大腸菌の構築2016
- Author(s)
  徳山健斗、戸谷吉博、清水浩
- Organizer
  化学工学会第48回秋季大会
- Place of Presentation
  徳島大学　常三島キャンパス（徳島県徳島市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] Integration of in silico design and experimental evaluation of metabolic pathways for creation of microbial cell factories,2016
- Author(s)
  Hiroshi Shimizu
- Organizer
  International Conference on the Metabolic Science,
- Place of Presentation
  Nanjiao Hotel, Shanghai China,
- Year and Date
  2016-10-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 大腸菌による効率的なメバロン酸生産のための代謝解析2016
- Author(s)
  戸谷吉博、和田圭介、増田亜美、徳山健斗、坂野聡美、吉川勝徳、松田史生、清水浩
- Organizer
  化学工学会第48回秋季大会
- Place of Presentation
  徳島大学　常三島キャンパス（徳島県徳島市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] メバロン酸生産大腸菌株の定常期における代謝状態の解明2016
- Author(s)
  増田亜美,戸谷　吉博、徳山健斗、坂野　聡美、吉川　勝徳、清水　浩
- Organizer
  第68回日本生物工学会大会（2016）
- Place of Presentation
  冨山国際会議場　ANAクラウンプラザホテル富山（富山県富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 13C-Metabolic Flux Analysis for Mevalonate-Producing Strain of Escherichia coli.2016
- Author(s)
  Wada, K., Toya, Y., Matsuda, F. and Shimizu, H.
- Organizer
  Metabolic Engineering 11
- Place of Presentation
  Awaji Yumebutai（兵庫県淡路市）
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] グリセロールからのコハク酸生産に向けたin silico代謝設計と実験評価2016
- Author(s)
  徳山健斗、戸谷吉博、清水浩
- Organizer
  2016年度生物工学若手研究者の集い（若手会）夏のセミナー
- Place of Presentation
  ホテルコンチネンタル府中（東京都府中市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] Metabolic flux measurement for efficient mevalonate production in Escherichia coli2016
- Author(s)
  Yoshihiro Toya, Keisuke Wada, Ami Masuda, Kento Tokuyama, Satomi Banno, Katsunori Yoshikawa, Fumio Matsuda, Hiroshi Shimizu
- Organizer
  i-BioP2016
- Place of Presentation
  Haeundae Grand Hotel , Busan, South Korea
- Year and Date
  2016-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04576
[Presentation] 13C-metabolic flux analysis for rational design of metabolic pathway modification of the industrially useful microorganisms2016
- Author(s)
  Hiroshi Shimizu
- Organizer
  The 13th International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  East Lake Hotel, Wuhan, China
- Year and Date
  2016-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 代謝フラックスを基盤とする物質生産法の開発2016
- Author(s)
  清水　浩、松田　史生、戸谷　吉博
- Organizer
  2016年農芸化学会
- Place of Presentation
  札幌教育文化会館大ホール（北海道札幌市）
- Year and Date
  2016-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 代謝物濃度絶対定量によるシアノバクテリア代謝律速点の解析2016
- Author(s)
  西口大貴, 永井暉, 松田史生, 清水浩
- Organizer
  第10回メタボロームシンポジウム
- Place of Presentation
  鶴岡メタボロームキャンパス（山形県鶴岡市）
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PLANNED-16H06559
[Presentation] 全自動実験室進化システムを用いた多系列・多種ストレス環境の実験室進化による大腸菌のストレス適応戦略の解析2015
- Author(s)
  堀之内貴明、鈴木真吾、清水浩、古澤力
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸公債会議場（兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Synechocystis sp. PCC 6803光化学系の定量プロテオーム分析系の構築2015
- Author(s)
  植林希代加、松田史生、日浅夏希、小倉泰郎、平野一郎、清水浩
- Organizer
  ラン藻の分子生物学2015
- Place of Presentation
  かずさアカデミアホール（千葉県木更津市）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 全自動実験室進化による様々な化合物ストレスに対する耐性大腸菌の創生と耐性化機構の解析2015
- Author(s)
  堀之内貴明、鈴木真吾、清水浩、古澤力
- Organizer
  第６７回日本生物工学大会
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 微生物による物質生産のための代謝デザインと細胞評価2015
- Author(s)
  清水浩
- Organizer
  近畿バイオインダストリー振興会議第31回バイオマス研究会講演会
- Place of Presentation
  大阪科学技術センター，大阪
- Year and Date
  2015-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 13C代謝フラックス解析に用いる13C標識炭素源の最適化2015
- Author(s)
 前田昂亮、岡橋伸幸、松田史生、清水浩
- Organizer
 日本質量分析学会第63回質量分析総合討論会 2015
- Place of Presentation
 つくば国際会議場エポカルつくば（茨城県つくば市）
- Year and Date
 2015-06-17
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] 大腸菌代謝フラックス解析の実験デザインの最適化2015
- Author(s)
  前田昂亮、岡橋伸幸、松田史生、清水浩
- Organizer
  第67回日本生物工学会大会（2015）
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 光合成微生物Synechocystis sp. PCC 6803中心代謝酵素の定量プロテオミクス2015
- Author(s)
 日浅夏希、松田史生、小倉泰郎、平野一郎、清水浩
- Organizer
 日本質量分析学会第63回質量分析総合討論会 2015
- Place of Presentation
 つくば国際会議場エポカルつくば（茨城県つくば市）
- Year and Date
 2015-06-17
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] 物質生産のための代謝デザインと細胞評価2014
- Author(s)
  清水浩
- Organizer
  新化学技術推進協会（JACI）
- Place of Presentation
  新化学技術推進協会（JACI），東京
- Year and Date
  2014-12-09
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Synechocystis sp. PCC 6803の強光耐性株の解析2014
- Author(s)
 吉川勝徳、小川健一、秋本誠志、清水浩
- Organizer
 第55回日本植物生理学会年会
- Place of Presentation
 富山大学(富山)
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] 代謝シミュレーションを用いた、微生物によるものづくりのための多重遺伝子破壊探索手法の開発2014
- Author(s)
  大野聡, 清水浩、古澤力
- Organizer
  生命情報若手の会　第5回研究会
- Place of Presentation
  東京大学検見川セミナーハウス（千葉）
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 微細藻細胞工場の創製のための代謝工学基盤技術開発2014
- Author(s)
  清水浩
- Organizer
  "未来へのバイオ技術"勉強会「藻類が拓くグリーンバイオ成長戦略のラストステージ」
- Place of Presentation
  バイオインダストリー協会，東京
- Year and Date
  2014-08-18
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 人工進化実験によるSynechocystis sp. PCC 6803へのイソブタノール耐性の賦与2014
- Author(s)
 松迫卓也、仲嶋翼、吉川勝徳、清水浩
- Organizer
 日本農芸化学大会2014大会
- Place of Presentation
 明治大学（東京）
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] 全自動実験室進化システムの構築と大腸菌の多系列・多種ストレス環境下での実験室進化2014
- Author(s)
  堀之内貴明，源晃明，鈴木真吾，清水浩，古澤力
- Organizer
  生命情報科学若手の会第5回研究会
- Place of Presentation
  東京大学　検見川セミナーハウス(千葉)
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Systems metabolic engineering - Rational design of microbial cell factories2013
- Author(s)
  Hiroshi Shimizu
- Organizer
  Asian Congress on Biotechnology 2013
- Place of Presentation
  Indian Institute of Technology Delhi（India）
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] International collaborative research on systems metablic engineering for low carbon society2013
- Author(s)
  Hiroshi Shimizu
- Organizer
  Biochemical and Molecular engineering XVIII
- Place of Presentation
  Beijing Pharma and Biotech Center, Beijing（China）
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] ラボオートメーションによる全自動多系列実験室進化システムの構築2013
- Author(s)
  堀之内貴明, 源晃明, 鈴木真吾, 清水浩, 古澤力
- Organizer
  第65回日本生物工学会大会
- Place of Presentation
  広島国際会議場(広島)
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 代謝シミュレーションに基づいた3HP高生産大腸菌の構築2013
- Author(s)
  徳山健斗、大野聡、吉川勝徳、古澤力、清水浩
- Organizer
  生物工学会
- Place of Presentation
  広島国際会議場(広島)
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] in silicoスクリーニングにより代謝物質生産が予測された大腸菌多重遺伝子破壊株の特徴解析2013
- Author(s)
 大野聡, 古澤力、清水浩
- Organizer
 生物工学会
- Place of Presentation
 広島国際会議場(広島)
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] 全自動実験室進化システムによる大腸菌の多系列・多種ストレス環境の実験室進化2013
- Author(s)
  堀之内貴明，源晃明，鈴木真吾，清水浩，古澤力
- Organizer
  第36回日本分子生物学会年会（MBSJ2013)
- Place of Presentation
  神戸国際会議場(兵庫)
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Systems metabolic engineering for creation of superior microbial cell factories2012
- Author(s)
  Hiroshi Shimizu
- Organizer
  Systems Biotechnology of Microalgae for Bioproduction, International Symposium and Exhibition
- Place of Presentation
  EXCO, Daegu, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Application of Genome Scale Models to Design of Microbial Cell Factories2012
- Author(s)
  Hiroshi Shimizu
- Organizer
  2nd Conference on Constraint-based Reconstruction and Analysis (COBRA 2012)
- Place of Presentation
  Hotel Marienlyst, Helsingør, Denmark
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Integration of in silico and experimental approaches for creation of microbial cell factories2012
- Author(s)
  Hiroshi Shimizu
- Organizer
  14th Asia Pacific Confederation of Chemical Engineering(APCChE 2012)
- Place of Presentation
  Suntec Singapore International Convention & Exhibition Center, Singapore
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Systems Metabolic Engineering -Rational Design of Microbial Cell Factories2012
- Author(s)
  Hiroshi Shimizu
- Organizer
  第64回日本生物工学会大会
- Place of Presentation
  神戸国際会議場,兵庫
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Genome-wide multi-omics analysis of ethanol stress tolerant strain of Escherichia2012
- Author(s)
  Hiroshi Shimizu
- Organizer
  Metabolic Engineering IX
- Place of Presentation
  Le Bellevue Congress and Exhibition centre in Biarritz, France
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] Integration of in silico and experimental approaches for creation of microbial cell factories2012
- Author(s)
  Hiroshi Shimizu
- Organizer
  14th Asia Pacific Confederation of Chemical Engineering (APCChE 2012)
- Place of Presentation
  Suntec Singapore International Convention & Exhibition Center (Singapore)(招待講演)
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Systems Metabolic Engineering for Bioproduction Development2011
- Author(s)
  Hiroshi Shimizu
- Organizer
  International Union of Microbiological Societies 2011 Congress(IUMS2011)
- Place of Presentation
  Sapporo Convention Center
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-23656526
[Presentation] Genome Scale Metabolic Flux Design and Experimental Evaluation of Cellular Performance2011
- Author(s)
  Hiroshi Shimizu
- Organizer
  The 2nd iBioP Asian Symposium (iBioP2011)
- Place of Presentation
  POSTECH (Pohang University of Science and Technology), Pohang, (South Korea)
- Data Source
  KAKENHI-PROJECT-23656526
[Presentation] 大腸菌エタノール耐性進化株の次世代シーケンサを用いた全ゲノム解析2011
- Author(s)
  小野直亮, 堀之内貴明, 玉岡邦康, 鈴木真吾, 平沢敬, 古澤力, 四方哲也, 清水浩
- Organizer
  第64回日本生物工学会大会
- Place of Presentation
  東京農工大学
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] エタノールストレス環境下の進化実験により得られた大腸菌のゲノムワイドな変異解析と遺伝子発現解析2011
- Author(s)
  清水浩
- Organizer
  化学工学会第43回秋季大会
- Place of Presentation
  名古屋工業大学(愛知県)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Systems Metabolic Engineering for Bioproduction Development2011
- Author(s)
  Hiroshi Shimizu
- Organizer
  International Union of Microbiological Societies 2011 Congress(IUMS2011)
- Place of Presentation
  Sapporo Convention Center, Hokkaido (Japan)
- Data Source
  KAKENHI-PROJECT-23656526
[Presentation] Genome-Wide Mutational and Expression Analyses of Evolved Escherichia Coli Strains under Ethanol Stress2011
- Author(s)
  Naoaki Ono, Chikara Furusawa, Takaaki Horinouchi, Kuniyasu Tamaoka, Shingo Suzuki, Takashi Hirasawa, Tetsuya Yomo Hiroshi Shimizu
- Organizer
  Asian Congress on Biotechnology(ACB-2011)
- Place of Presentation
  Shanghai, China
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Whole genome resequencing of experimentally evolved Escherichia coli using a next generation sequencer2011
- Author(s)
  小野直亮, 堀之内貴明, 玉岡邦康, 鈴木真吾, 平沢敬, 古澤力, 四方哲也, 清水浩
- Organizer
  日本生物物理学会第49回年会
- Place of Presentation
  兵庫県立大学
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 人工進化工学と網羅的遺伝子発現情報解析によるストレス耐性細胞の創製2011
- Author(s)
  清水浩
- Organizer
  化学工学会第76年会
- Place of Presentation
  東京農工大学小金井キャンパス、東京都
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Genome Scale Metabolic Flux Design and Experimental Evaluation of Cellular Performance2011
- Author(s)
  Hiroshi Shimizu
- Organizer
  The 2nd iBioP Asian Symposium (iBioP2011)
- Place of Presentation
  POSTECH (Pohang University of Science and Technology), Pohang, South Korea
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23656526
[Presentation] エタノールストレス環境下の進化実験により得られた大腸菌のゲノムワイドな変異解析と遺伝子発現解2011
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 小野直亮, 鈴木真吾, 平沢敬, 四方哲也, 清水浩
- Organizer
  化学工学会第43回秋季大会
- Place of Presentation
  名古屋工業大学
- Year and Date
  2011-09-05
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 人工進化工学と網羅的遺伝子発現情報解析によるストレス耐性細胞の創製2011
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 小野直亮, 鈴木真吾, 平沢敬, 四方哲也, 清水浩
- Organizer
  化学工学会第76年会
- Place of Presentation
  東京農工大学
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Systems Biotechnology for Creation of Microbial Cell Factory2010
- Author(s)
  清水浩
- Organizer
  2010 International Symposium on Advanced Biological Engineering (ISABE'2010)
- Place of Presentation
  Beijing Friendship Hotel, Beijing (China)(招待講演)
- Year and Date
  2010-07-25
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 大腸菌エタノールストレス人工進化株の全ゲノム変異解析・遺伝子発現解析2010
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 平沢敬, 小野直亮, 鈴木真吾, 四方哲也, 清水浩
- Organizer
  定量生物学の会第二回年会
- Place of Presentation
  大阪大学
- Year and Date
  2010-01-09
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 複数時間スケールを持つ環境適応ダイナミクス:エタノールストレス環境下での大腸菌人工進化実験における網羅的表現型/遺伝子型解析2010
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 小野直亮, 鈴木真吾, 平沢敬, 四方哲也, 清水浩
- Organizer
  第48回生物物理学会年会
- Place of Presentation
  東北大学
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Systems Biotechnology for Creation of Microbial Cell Factroy2010
- Author(s)
  HiroshiShimizu
- Organizer
  2010 International Symposium on Advanced Biological Engineering(ISABE' 2010)
- Place of Presentation
  Beijing, China
- Year and Date
  2010-07-25
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 人工進化実験における発現制御ダイナミクスの進化的シミュレーション2010
- Author(s)
  堀之内貴明, 古澤力, 清水浩, 四方哲也, 小野直亮
- Organizer
  定量生物学の会第三回年会
- Place of Presentation
  東京大学生産技術研究所
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 大腸菌エタノールストレス人工進化株の網羅的解析によるエタノール耐性付与2010
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 平沢敬, 小野直亮, 鈴木真吾, 四方哲也, 清水浩
- Organizer
  定量生物学の会第三回年会
- Place of Presentation
  東京大学生産技術研究所
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] エタノール環境下での長期植え継ぎ培養によって得られた耐性大腸菌株の遺伝子発現・ゲノム変異解析2010
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 小野直亮, 鈴木真吾, 平沢敬, 四方哲也, 清水浩
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸ポートピアアイランド,兵庫県
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 次世代シーケンサを用いた大腸菌DH1株の全ゲノム解析2010
- Author(s)
  小野直亮, 鈴木真吾, 古澤力, 清水浩, 四方哲也
- Organizer
  第62回日本生物工学会大会
- Place of Presentation
  宮崎シーガイアワールドコンベンションセンターサミット
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 大腸菌エタノールストレス人工進化株の網羅的解析によるエタノール耐性付与2010
- Author(s)
  堀之内貴明、清水浩
- Organizer
  定量生物学の会第三回年会
- Place of Presentation
  東京大学生産技術研究所、東京都
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 人工進化実験によって得られたエタノール耐性大腸菌株の網羅的遺伝子発現解析とゲノム異変解析2010
- Author(s)
  堀之内貴明, 玉岡邦康, 古澤力, 小野直亮, 鈴木真吾, 平沢敬, 四方哲也, 清水浩
- Organizer
  宮崎シーガイアワールドコンベンションセンターサミット
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] タイリングアレイを用いたエタノール耐性大腸菌株のゲノム変異解析2009
- Author(s)
  玉岡邦康, 堀之内貴明, 古澤力, 平沢敬, 小野直亮, 鈴木真吾, 四方哲也, 清水浩
- Organizer
  第61回日本生物工学会大会
- Place of Presentation
  名古屋大学
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] Genome-Wide Mutational and Expression Analyses of Evolved Escherichia Coli Strains Under Ethanol Stress2009
- Author(s)
  Takaaki Horinouchi, Kuniyasu Tamaoka, Chikara Furusawa, Takashi Hirasawa, Naoaki Ono, Shingo Suzuki, Tetsuya Yomo, Hiroshi Shimizu
- Organizer
  The 20th International Conference on Genome Informatics(GIW 2009)
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2009-12-14
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] システムバイオテクノロジーによる生物生産2009
- Author(s)
  清水浩
- Organizer
  日本生物工学会第61回大会
- Place of Presentation
  名古屋大学
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] A model-based analysis method for detection of single-base substitution using resequencing microarrays2009
- Author(s)
  Naoaki Ono, Shingo Suzuki, Chikara Furusawa, Hiroshi Shimizu, Tetsuya Yomo
- Organizer
  Asia Pacific Biochemical Engineering Conference 2009(APBioChEC' 09)
- Place of Presentation
  Kobe, Japan
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] システムバイオテクノロジーによる生物生産2009
- Author(s)
  清水浩
- Organizer
  第61回日本生物工学会大会
- Place of Presentation
  名古屋大学
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] メイトペア情報に基づいた次世代シーケンサによるresequencing解析アルゴリズムの開発2009
- Author(s)
  小野直亮, 鈴木真吾, 古澤力, 清水浩, 四方哲也
- Organizer
  第61回日本生物工学会大会
- Place of Presentation
  名古屋大学
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] 次世代シーケンサにおけるメイトペアの距離情報を利用した配列解析アルゴリズムの開発2009
- Author(s)
  小野直亮, 鈴木真吾, 古澤力, 清水浩, 四方哲也
- Organizer
  第47回生物物理学会年会
- Place of Presentation
  徳島文理大学
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21360401
[Presentation] コリネ型細菌のグルタミン酸生産期における代謝フラックス解析法の確立と補充経路の役割の解明2007
- Author(s)
  白井、清水, ら6名
- Organizer
  日本生物工学会平成19年度大会
- Place of Presentation
  広島大学
- Year and Date
  2007-09-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Development of genome-scale metabolic analysis system of Corynebacterium glutamicum2007
- Author(s)
  Y., Shinfuku, H., Shimizu, et. al.
- Organizer
  Annual meeting of Society of the Society for Biotechnology Japan
- Place of Presentation
  Hiroshima University
- Year and Date
  2007-09-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Corynebacterium glutamicumのゲノムスケール代謝解析システムの開発2007
- Author(s)
  新福、清水, ら4名
- Organizer
  日本生物工学会平成19年度大会
- Place of Presentation
  広島大学
- Year and Date
  2007-09-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] ストレス環境下における酵母の遺伝子破壊株の網羅的解析2007
- Author(s)
  吉川、清水, ら6名
- Organizer
  日本生物工学会平成19年度大会
- Place of Presentation
  広島大学
- Year and Date
  2007-09-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Genome-wide analysis of yeast deletion mutants under stress conditions2007
- Author(s)
  K., Yoshikawa, H., Shimizu, et. al.
- Organizer
  Annual meeting of Society of the Society for Biotechnology Japan
- Place of Presentation
  Hiroshima University
- Year and Date
  2007-09-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Genetic engineering of the central metabolic pathway for succinate production in Saccharomyces cerevisiae2007
- Author(s)
  Yun Hee Jeong, H. Shimizu, ら4名
- Organizer
  ユネスコバイオテクノロジー国際大学院研修講座発表会
- Place of Presentation
  大阪大学
- Year and Date
  2007-09-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Inverse metabolic engineering by integration of multiple omics analyses2007
- Author(s)
  Hiroshi, Shimizu, et. al.
- Organizer
  10th Computer Application for Biotechnology (CABO8)
- Place of Presentation
  Cancun Mexico
- Year and Date
  2007-06-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Molecular Breeding based on Multi-Omics Analyses2007
- Author(s)
  H. Shimizu, ら8名
- Organizer
  Asia Pacific Biochemical Engineering 2007
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2007-11-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] 生物生産のためのシステムバイオテクノロジー2007
- Author(s)
  清水浩
- Organizer
  バイオインフォマティクス学会第17回システムバイオロジー研究会
- Place of Presentation
  奈良先端科学技術大学院大学
- Year and Date
  2007-11-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis2007
- Author(s)
  T., Shirai, H., Shimizu, et. al.
- Organizer
  Annual meeting of Society of the Society for Biotechnology Japan
- Place of Presentation
  Hiroshima University
- Year and Date
  2007-09-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Genome-wide analysis of yeast single gene deletion strains under osmotic and ethanol stress conditions2007
- Author(s)
  K., Yoshikawa, H., Shimizu, et. al.
- Organizer
  Annual Meeting of The Molecular Biology Society of Japan
- Place of Presentation
  Pacifico Yokohama
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Inverse metabolic engineering by integration of multiple omics analyses2007
- Author(s)
  H. Shimizu, ら8名
- Organizer
  10th Computer Applications in Biotechnology(CAB10), June 4-6, Vol. 1, 15-20,
- Place of Presentation
  Cancun Mexico
- Year and Date
  2007-06-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Genetic engineering if central carbon metabolic pathway for suucinate production in Saccharomyces cerevisiae2007
- Author(s)
  Y.H., Jeong, H., Shimizu, et. al.
- Organizer
  Final Presentation of The 3b UNESCO Postgraduate Inter-University Course in Biotechnology 2006. 2007
- Place of Presentation
  Osaka University
- Year and Date
  2007-09-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] 浸透圧・エタノールストレス環境下における酵母1遺伝子破壊株の網羅的解析2007
- Author(s)
  吉川、清水, ら6名
- Organizer
  日本分子生物学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Systems Biotechnology for Bio-Production2007
- Author(s)
  Hiroshi, Shimizu
- Organizer
  Japanese Society for Bioinformatics, the 17th meeting of division of Systems Biology
- Place of Presentation
  NAIST
- Year and Date
  2007-11-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Molecular breeding based on multi-omics analyses2007
- Author(s)
  Hiroshi, Shimizu, et. al.
- Organizer
  Asia Pacific Biochemical Engineering 2007
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2007-11-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Inverse metabolic engineering by integration of multiple omics analyses2007
- Author(s)
  H. Shimizu, ら8名
- Organizer
  10th Computer Applications in Biotechnology (CAB10), June 4-6, Vol. 1, 15-20,
- Place of Presentation
  Cancun Mexico
- Year and Date
  2007-06-05
- Data Source
  KAKENHI-PROJECT-18360395
[Presentation] Integration of in silico Design and Experimental Evaluation for Creation of Microbial Cell Factories
- Author(s)
  Hiroshi Shimizu
- Organizer
  Metabolic Engineering X
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-15 – 2014-06-19
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 人工進化実験によるSynechocystis sp. PCC 6803のイソブタノール耐性株の取得と変異解析
- Author(s)
  松迫卓也、　仲嶋翼、　吉川勝徳、清水浩
- Organizer
  第5回日本光合成学会年会
- Place of Presentation
  近畿大学農学部，奈良
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 大腸菌を用いた定常期におけるメバロン酸生産
- Author(s)
  増田亜美、戸谷吉博、徳山健斗、坂野聡美、吉川勝徳、清水浩
- Organizer
  日本農芸化学会大会2015
- Place of Presentation
  岡山大学津島キャンパス，岡山
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] in silico代謝予測に基づいた3-ヒドロキシプロピオン酸高生産大腸菌の構築
- Author(s)
  徳山健斗、大野聡、吉川勝徳、古澤力、清水浩
- Organizer
  生物工学若手の会　夏のセミナー2014
- Place of Presentation
  神戸セミナーハウス，兵庫
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 細胞内遊離代謝物質の13C標識情報に基づくフラックス解析法の構築
- Author(s)
  岡橋　伸幸、梶畠　秀一、古澤　力、清水　浩
- Organizer
  生物工学若手の会　夏のセミナー2014
- Place of Presentation
  神戸セミナーハウス，兵庫
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] 人工進化実験によるSynechocystis sp. PCC 6803 のイソブタノール耐性株の獲得と変異解析
- Author(s)
 松迫卓也、仲嶋翼、吉川勝徳、清水浩
- Organizer
 第66回日本生物工学会大会（2014）
- Place of Presentation
 札幌コンベンションセンター，北海道
- Year and Date
 2014-09-09 – 2014-09-11
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] Integration of in silico and Experimental Approaches for Creation of Microbial Cell Factories
- Author(s)
  Hiroshi Shimizu
- Organizer
  2014 KSBB Spring Meeting and International
- Place of Presentation
  Gyeongju, Korea
- Year and Date
  2014-04-09 – 2014-04-11
- Invited
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] グリセロール単一炭素源における正確な代謝フラックス推定のための13C標識条件の検討
- Author(s)
 大橋秀伍、戸谷吉博、清水浩
- Organizer
 第66回日本生物工学会大会（2014）
- Place of Presentation
 札幌コンベンションセンター，北海道
- Year and Date
 2014-09-09 – 2014-09-11
- Data Source
 KAKENHI-PROJECT-24246134
[Presentation] 微生物育種に向けた多重遺伝子破壊のin silicoスクリーニング
- Author(s)
  大野　聡、古澤　力、清水　浩
- Organizer
  生物工学若手の会　夏のセミナー2014
- Place of Presentation
  神戸セミナーハウス，兵庫
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24246134
[Presentation] フラックスバランス解析に基づく有用物質生産微生物の構築
- Author(s)
  清水　浩、吉川　勝徳、古澤力、平沢　敬、戸谷　吉博、松田　史生
- Organizer
  第46回化学工学会秋季大会
- Place of Presentation
  九州大学　伊都キャンパス，福岡
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-24246134

1. SHIOYA Suetaki (50026259)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
2. TOYA YOSHIHIRO (70582162)

# of Collaborated Projects: 8 results

# of Collaborated Products: 102 results
3. FURUSAWA Chikara (00372631)

# of Collaborated Projects: 6 results

# of Collaborated Products: 50 results
4. NAGAHISA Keisuke (00324806)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. HIRASAWA Takashi (20407125)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
6. SUGA Ken-ichi (20029250)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. MATSUDA FUMIO (50462734)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
8. OMASA Takeshi (00252586)

# of Collaborated Projects: 3 results

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9. UCHIYAMA Keiji (60294039)

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10. 二井手哲平 (20802705)

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# of Collaborated Products: 2 results
11. NAKAJIMA Mikio (00273590)

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12. 堀之内貴明 (60610988)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
13. ONO Naoaki (60395118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
14. YOSHIKAWA KATSUNORI (20599279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
15. KATAKURA Yoshio (50263207)

# of Collaborated Projects: 1 results

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16. NINOMIYA Kazuaki (10379125)

# of Collaborated Projects: 1 results

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17. Minagawa Jun (80280725)

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18. 江夏敏郎 (20029010)

# of Collaborated Projects: 1 results

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19. 小山内崇 (60512316)

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# of Collaborated Products: 4 results
20. 坂本亘 (20222002)

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21. 園池公毅 (30226716)

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22. 宗景ゆり (30423247)

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23. 久堀徹 (40181094)

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24. 魚住信之 (40223515)

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25. 高橋裕一郎 (50183447)

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26. 鹿内利治 (70273852)

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27. 栗栖源嗣 (90294131)

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28. 矢守航 (90638363)

# of Collaborated Projects: 1 results

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29. 鈴木宏明 (20372427)

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# of Collaborated Products: 4 results
30. 堀克敏 (50302956)

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31. 津川裕司 (30647235)

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32. 吉本将悟 (90806291)

# of Collaborated Projects: 1 results

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33. Takahashi Chihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. KATO Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 山田真紀

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36. 長野稔

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# of Collaborated Products: 1 results

SHIMIZU Hiroshi 清水 浩

SHIMIZU Hioroshi 清水 浩

Research Projects

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Co-Researchers

リボゾーム結合部位配列の改変による大腸菌代謝フラックスの制御と物質生産への応用Principal Investigator

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Systems analysis of photosynthesis and metabolism of cyanobacteria under fluctuation light conditionPrincipal Investigator

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High performance microbial cell factories development by model based metabolic design and adaptive laboratory evolutionPrincipal Investigator

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Identification of rate limiting step in metabolic pathway for bioproductions based on genome scale modelPrincipal Investigator

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Development of Simulation System of Cancer MetabolismPrincipal Investigator

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Intracellular metabolism control of the proton motive forcePrincipal Investigator

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Identification of Limiting Step and Optimization of Metabolism based on Analysis of Dynamic Behaviors of Multilayers Omics DataPrincipal Investigator

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Creation of Stress Tolerant Microbial Cell Factories based on Multiomics Analysis of Laboratory Evolution ProcessPrincipal Investigator

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Study on inhibitory effect of high light on the cell growth and adaptation mechanism of cyanobacteriaPrincipal Investigator

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Creation of stress tolerant strain based on single nucleotide mutational analysis of in whole genomePrincipal Investigator

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In silica Design of Metabolic Pathway of Yet for Bio-ProductionofEnvironmental-Conscious Chemical ProductsPrincipal Investigator

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SHIMIZU Hiroshi 清水浩

SHIMIZU Hioroshi 清水浩