Tsugawa Hiroshi 津川裕司

… Alternative Names

Researcher Number	30647235
Other IDs	https://orcid.org/0000-0002-2015-3958
Affiliation (Current)	2021: 東京農工大学, 工学(系)研究科(研究院), 准教授 2021: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員
Affiliation (based on the past Project Information) *help	2021: 国立研究開発法人理化学研究所, その他部局等, 研究員 2016 – 2020: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員 2015: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 特別研究員 2013 – 2014: 独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員
Review Section/Research Field	Principal Investigator Biomolecular chemistry / Medium-sized Section 37:Biomolecular chemistry and related fields / Life / Health / Medical informatics / Basic Section 43060:System genome science-related
Keywords	Principal Investigator メタボロミクス / 化合物同定 / 質量分析 / インフォマティクス / 質量分析インフォマティクス / メタボローム解析 / バイオインフォマティクス / リピドミクス / LC-MS/MS / メタボローム … More

質量分析インフォマティクスの開拓による生薬作用分子メカニズムの解明Principal InvestigatorOngoing
- Principal Investigator
  
  津川裕司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Institute of Physical and Chemical Research
Identifying epimetabolites and its elucidations by computational mass spectrometryPrincipal InvestigatorOngoing
- Principal Investigator
  
  津川裕司
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Institute of Physical and Chemical Research
Illuminating new biological mechanisms by multiomics approach with mass spectrometry cheminformaticsPrincipal InvestigatorOngoing
- Principal Investigator
  
  津川裕司
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Institute of Physical and Chemical Research
Development of next generation untaregeted metabolomics methodologies using LC-MS/MSPrincipal Investigator
- Principal Investigator
  
  Tsugawa Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Institute of Physical and Chemical Research
Development of a data processing system for LC-QqQ/MS based metabolomicsPrincipal Investigator
- Principal Investigator
  
  TSUGAWA Hiroshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Life / Health / Medical informatics
  Biomolecular chemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Metabolomics with 15N Labeling for Characterizing Missing Monoterpene Indole Alkaloids in Plants2020
- Author(s)
  Nakabayashi Ryo、Mori Tetsuya、Takeda Noriko、Toyooka Kiminori、Sudo Hiroshi、Tsugawa Hiroshi、Saito Kazuki
- Journal Title
  
  Analytical Chemistry
  
  Volume: 92 Pages: 5670-5675
- DOI
  10.1021/acs.analchem.9b03860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19155, KAKENHI-PROJECT-18H02432, KAKENHI-PROJECT-17K07477
[Journal Article] Mass spectrometry data repository enhances novel metabolite discoveries with advances in computational metabolomics2019
- Author(s)
  Tsugawa Hiroshi、Satoh Aya、Uchino Haruki、Cajka Tomas、Arita Makoto、Arita Masanori
- Journal Title
  
  Metabolites
  
  Volume: 9 Pages: 119-119
- DOI
  10.3390/metabo9060119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19155, KAKENHI-INTERNATIONAL-15K21738, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-18H02432
[Journal Article] A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms.2019
- Author(s)
  Tsugawa Hiroshi、Nakabayashi Ryo、Mori Tetsuya、Yamada Yutaka、Takahashi Mikiko、Rai Amit、Sugiyama Ryosuke、Yamamoto Hiroyuki、Nakaya Taiki、Yamazaki Mami、Kooke Rik、Bac-Molenaar Johanna A.、Oztolan-Erol Nihal、Keurentjes Joost J. B.、Arita Masanori、Saito Kazuki
- Journal Title
  
  Nat Methods
  
  Volume: 16 Pages: 295-298
- DOI
  10.1038/s41592-019-0358-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14348, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-18K19155, KAKENHI-INTERNATIONAL-15K21738, KAKENHI-PLANNED-16H06454, KAKENHI-PROJECT-18H02432, KAKENHI-PROJECT-17H03621
[Journal Article] Characterization of lipid profiles after dietary intake of polyunsaturated fatty acids using integrated untargeted and targeted lipidomics.2019
- Author(s)
  Naoe Satoko、Tsugawa Hiroshi、Takahashi Mikiko、Ikeda Kazutaka、Arita Makoto
- Journal Title
  
  Metabolites
  
  Volume: 9 Pages: 241-241
- DOI
  10.3390/metabo9100241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19155, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-18H02432
[Journal Article] Creating a Reliable Mass Spectral?Retention Time Library for All Ion Fragmentation-Based Metabolomics2019
- Author(s)
  Tada Ipputa、Tsugawa Hiroshi、Meister Isabel、Zhang Pei、Shu Rie、Katsumi Riho、Wheelock Craig E.、Arita Masanori、Chaleckis Romanas
- Journal Title
  
  Metabolites
  
  Volume: 9 Pages: 251-251
- DOI
  10.3390/metabo9110251
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19155, KAKENHI-PROJECT-19K17662, KAKENHI-INTERNATIONAL-15K21738, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-18H02432, KAKENHI-PROJECT-18F17774, KAKENHI-PROJECT-18J23133, KAKENHI-PROJECT-19K21239
[Journal Article] Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics2018
- Author(s)
  Lai Z, Tsugawa H, Wohlgemuth G, Mehta S, Mueller M, Zheng Y, Ogiwara A, Meissen J, Showalter M, Takeuchi K, Kind T, Beal P, Arita M, Fiehn O
- Journal Title
  
  Nat Methods
  
  Volume: 15 Pages: 53-56
- DOI
  10.1038/nmeth.4512
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21738, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15K01812, KAKENHI-PROJECT-17H03621, KAKENHI-PROJECT-18H02432
[Journal Article] Advances in computational metabolomics and databases deepen the understanding of metabolisms2018
- Author(s)
  Hiroshi Tsugawa
- Journal Title
  
  Current opinion in biotechnology
  
  Volume: 54 Pages: 10-17
- DOI
  10.1016/j.copbio.2018.01.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01812, KAKENHI-PROJECT-18K19155, KAKENHI-PROJECT-18H02432
[Journal Article] Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library2017
- Author(s)
  Tsugawa H, Ikeda K, Tanaka W, Senoo Y, Arita M, Arita M.
- Journal Title
  
  Journal of cheminformatics
  
  Volume: 9 Pages: 19-19
- DOI
  10.1186/s13321-017-0205-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-15K01812, KAKENHI-PROJECT-17H03621
[Journal Article] Integrated strategy for unknown EI-MS identification using quality control calibration curve, multivariate analysis, EI-MS spectral database, and retention index prediction.2017
- Author(s)
  Teruko Matsuo, Hiroshi Tsugawa, Hiromi Miyagawa, Eiichiro Fukusaki
- Journal Title
  
  Analytical Chemistry
  
  Volume: 2017 Pages: 6766-6773
- DOI
  10.1021/acs.analchem.7b01010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01812
[Journal Article] The importance of bioinformatics for connecting data-driven lipidomics and biological insights2017
- Author(s)
  Tsugawa H, Ikeda K, Arita M.
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  
  Volume: 1862 Pages: 762-765
- DOI
  10.1016/j.bbalip.2017.05.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-15K01812
[Journal Article] Hydrogen rearrangement rules: computational MS/MS fragmentation and structure elucidation using MS-FINDER software2016
- Author(s)
  Tsugawa H, Kind T, Nakabayashi R, Yukihira D, Tanaka W, Cajka T, Saito K, Fiehn O, Arita M
- Journal Title
  
  Analytical Chemistry
  
  Volume: 88 Pages: 7946-7958
- DOI
  10.1021/acs.analchem.6b00770
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15K01812
[Journal Article] MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis.2015
- Author(s)
  Hiroshi Tsugawa, Tomas Cajka, Tobias Kind, Yan Ma, Brendan Higgins, Kazutaka Ikeda, Mitsuhiro Kanazawa, Jean VanderGheynst, Oliver Fiehn, Masanori Arita
- Journal Title
  
  Nat Methods
  
  Volume: 12 Pages: 523-526
- DOI
  10.1038/nmeth.3393
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01812, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898
[Journal Article] MRM-DIFF: data processing strategy for differential analysis in large scale MRM-based lipidomics studies.2015
- Author(s)
  Tsugawa H, Ohta E, Izumi Y, Ogiwara A, Yukihira D, Bamba T, Fukusaki E, Arita M.
- Journal Title
  
  Front Genet.
  
  Volume: 5 Pages: 471-471
- DOI
  10.3389/fgene.2014.00471
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24700455, KAKENHI-PROJECT-25871136, KAKENHI-PROJECT-26505007, KAKENHI-PROJECT-15K06557
[Journal Article] MRMPROBS suite for metabolomics using large-scale MRM assays2014
- Author(s)
  Hiroshi Tsugawa, Mitsuhiro Kanazawa, Atsushi Ogiwara, Masanori Arita
- Journal Title
  
  Bioinformatics
  
  Volume: 30 Pages: 2379-2380
- DOI
  10.1093/bioinformatics/btu203
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] Different-batch metabolome analysis of Saccharomyces cerevisiae based on gas chromatography/mass spectrometry2014
- Author(s)
  Naoki Kawase, Hiroshi Tsugawa, Takeshi Bamba, Eiichiro Fukusaki
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 117 Issue: 2 Pages: 248-255
- DOI
  10.1016/j.jbiosc.2013.07.008
- NAID
  110009804081
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry2014
- Author(s)
  Hiroshi Tsugawa, Yuki Tsujimoto, Kuniyo Sugitate, Norihiro Sakui, Shin Nishiumi, Takeshi Bamba, Eiichiro Fukusaki
- Journal Title
  
  Journal of bioscience and bioengineering
  
  Volume: 117 Pages: 122-128
- NAID
  110009766615
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry2014
- Author(s)
  Hiroshi Tsugawa, Yuki Tsujimoto, Kuniyo Sugitate, Norihiro Sakui, Shin Nishiumi, Takeshi Bamba, Eiichiro Fukusaki
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 117 Issue: 1 Pages: 122-128
- DOI
  10.1016/j.jbiosc.2013.06.009
- NAID
  110009766615
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] MRMPROBS: A Data Assessment and Metabolite Identification Tool for Large-Scale Multiple Reaction Monitoring Based Widely Targeted Metabolomics2013
- Author(s)
  Tsugawa, H., Arita, M., Kanazawa, M., Ogiwara, A., Bamba, T., Fukusaki, E
- Journal Title
  
  Analytical Chemistry
  
  Volume: 85(10) Pages: 5191-5199
- DOI
  10.1021/ac400515s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23686120, KAKENHI-PROJECT-24656503, KAKENHI-PROJECT-25871136
[Journal Article] Method for Assessing the Statistical Significance of Mass Spectral Similarities Using Basic Local Alignment Search Tool Statistics2013
- Author(s)
  松田史生、福崎英一郎
- Journal Title
  
  Analytical Chemistry
  
  Volume: 85 Pages: 8291-8217
- DOI
  10.1021/ac401564v
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25820400, KAKENHI-PROJECT-25871136
[Presentation] PlaSMA: decoding plant specialized metabolome by the suite of mass spectrometry cheminformatics2018
- Author(s)
  Hiroshi Tsugawa, Ryo Nakabayashi, Amit Rai, Tetsuya Mori, Yutaka Yamada, Hiroyuki Yamamoto, Makoto Arita, Masanori Arita, Kazuki Saito
- Organizer
  Metabolomics conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19155
[Presentation] MRMPROBS: Multiple reaction monitoringを用いた定量メタボロミクス研究に資するピーク評価方法ならびにデータ解析ソフトウェアの開発2013
- Author(s)
  津川裕司
- Organizer
  第８回メタボロームシンポジウム
- Place of Presentation
  九州大学, 福岡市東区馬出３丁目１番１号
- Data Source
  KAKENHI-PROJECT-25871136
[Presentation] MRMPROBS: Data Assessment and Metabolite Identification Tool for Large-scale MRM-based Widely Targeted Metabolomics2013
- Author(s)
  Hiroshi Tsugawa
- Organizer
  American Society for Mass Spectrometry Annual Conference
- Place of Presentation
  ミネアポリス，USA
- Data Source
  KAKENHI-PROJECT-25871136
[Presentation] MRMPROBS：Multiple reaction monitoringを用いたワイドターゲットメタボローム解析のためのピーク評価法ならびにデータ解析ソフトウェアの開発2013
- Author(s)
  津川裕司
- Organizer
  第61回質量分析討論会
- Place of Presentation
  つくば国際会議場, 茨城県つくば市竹園２丁目２０－３
- Data Source
  KAKENHI-PROJECT-25871136

1. NAKABAYSHI Ryo (30586160)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. ARITA Masanori (10356389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. SAITO Kazuki (00146705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. ARITA Makoto (80292952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. IKEDA Kazutaka (10466732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. FIEHN Oliver

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. LAI Zijuan

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. KIND Tobias

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. CAJKA Tomas

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. WOHLGEMUTH Gert

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MEHTA Sajjan

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. MUELLER Matthew

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. Fukusaki Eiichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. IZUMI Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 福崎英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 馬場健史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 田中謙

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 杉山龍介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 山崎真巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. CHALECKIS ROMANA

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. MEISTER ISABEL

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. ZHANG PEI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 松田史生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 豊岡公徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsugawa Hiroshi 津川 裕司

TSUGAWA Hiroshi 津川 裕司

Research Projects

Research Products

Co-Researchers

質量分析インフォマティクスの開拓による生薬作用分子メカニズムの解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying epimetabolites and its elucidations by computational mass spectrometryPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Illuminating new biological mechanisms by multiomics approach with mass spectrometry cheminformaticsPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of next generation untaregeted metabolomics methodologies using LC-MS/MSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a data processing system for LC-QqQ/MS based metabolomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Metabolomics with 15N Labeling for Characterizing Missing Monoterpene Indole Alkaloids in Plants2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mass spectrometry data repository enhances novel metabolite discoveries with advances in computational metabolomics2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of lipid profiles after dietary intake of polyunsaturated fatty acids using integrated untargeted and targeted lipidomics.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Creating a Reliable Mass Spectral?Retention Time Library for All Ion Fragmentation-Based Metabolomics2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Advances in computational metabolomics and databases deepen the understanding of metabolisms2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrated strategy for unknown EI-MS identification using quality control calibration curve, multivariate analysis, EI-MS spectral database, and retention index prediction.2017

Author(s)

Journal Title

DOI

Data Source

Tsugawa Hiroshi 津川裕司

TSUGAWA Hiroshi 津川裕司

[Presentation] MRMPROBS: Multiple reaction monitoringを用いた定量メタボロミクス研究に資するピーク評価方法ならびにデータ解析ソフトウェアの開発2013

[Presentation] MRMPROBS：Multiple reaction monitoringを用いたワイドターゲットメタボローム解析のためのピーク評価法ならびにデータ解析ソフトウェアの開発2013