TSUGAWA Hiroshi 津川裕司

Researcher Number	30647235
Affiliation *help	2016 – 2018 : 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員 2015 – 2016 : 国立研究開発法人理化学研究所, 環境資源科学研究センター, 特別研究員 2013 – 2014 : 独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員
Review Section/Research Field	Principal Investigator Biomolecular chemistry / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 43060:System genome science-related / Life / Health / Medical informatics
Keywords	Principal Investigator 化合物同定 / 質量分析 / メタボロミクス / インフォマティクス / ノンターゲット解析 / エピメタボライト / 質量分析インフォマティクス / LC/QqQ/MS / ワイドターゲット解析 / メタボローム解析 … More

Illuminating new biological mechanisms by multiomics approach with mass spectrometry cheminformaticsPrincipal InvestigatorOngoing
- Principal Investigator
  
  津川裕司
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Institute of Physical and Chemical Research
Identifying epimetabolites and its elucidations by computational mass spectrometryPrincipal InvestigatorOngoing
- Principal Investigator
  
  津川裕司
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Institute of Physical and Chemical Research
Development of next generation untaregeted metabolomics methodologies using LC-MS/MSPrincipal Investigator
- Principal Investigator
  
  津川裕司
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Institute of Physical and Chemical Research
Development of a data processing system for LC-QqQ/MS based metabolomicsPrincipal Investigator
- Principal Investigator
  
  TSUGAWA Hiroshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Life / Health / Medical informatics
  Biomolecular chemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2018 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics2018
- Author(s)
  Lai Zijuan、Tsugawa Hiroshi、Wohlgemuth Gert、Mehta Sajjan、Mueller Matthew、Zheng Yuxuan、Ogiwara Atsushi、Meissen John、Showalter Megan、Takeuchi Kohei、Kind Tobias、Beal Peter、Arita Masanori、Fiehn Oliver
- Journal Title
  
  Nature Methods
  
  Volume : 15 Pages : 53-56
- DOI
  10.1038/nmeth.4512
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15K01812, KAKENHI-INTERNATIONAL-15K21738
[Journal Article] Advances in computational metabolomics and databases deepen the understanding of metabolisms2018
- Author(s)
  Hiroshi Tsugawa
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume : 54 Pages : 10-17
- DOI
  10.1016/j.copbio.2018.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01812
[Journal Article] Integrated strategy for unknown EI-MS identification using quality control calibration curve, multivariate analysis, EI-MS spectral database, and retention index prediction.2017
- Author(s)
  Teruko Matsuo, Hiroshi Tsugawa, Hiromi Miyagawa, Eiichiro Fukusaki
- Journal Title
  
  Analytical Chemistry
  
  Volume : 2017 Pages : 6766-6773
- DOI
  10.1021/acs.analchem.7b01010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01812
[Journal Article] Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library2017
- Author(s)
  Tsugawa H, Ikeda K, Tanaka W, Senoo Y, Arita M, Arita M.
- Journal Title
  
  Journal of cheminformatics
  
  Volume : 9 Pages : 19-19
- DOI
  10.1186/s13321-017-0205-3
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-15K01812
[Journal Article] The importance of bioinformatics for connecting data-driven lipidomics and biological insights2017
- Author(s)
  Tsugawa H, Ikeda K, Arita M.
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  
  Volume : 1862 Pages : 762-765
- DOI
  10.1016/j.bbalip.2017.05.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-15K01812
[Journal Article] Hydrogen rearrangement rules: computational MS/MS fragmentation and structure elucidation using MS-FINDER software2016
- Author(s)
  Tsugawa H, Kind T, Nakabayashi R, Yukihira D, Tanaka W, Cajka T, Saito K, Fiehn O, Arita M
- Journal Title
  
  Analytical Chemistry
  
  Volume : 88 Pages : 7946-7958
- DOI
  10.1021/acs.analchem.6b00770
- Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15K01812
[Journal Article] MRM-DIFF: data processing strategy for differential analysis in large scale MRM-based lipidomics studies2015
- Author(s)
  Tsugawa H, Ohta E, Izumi Y, Ogiwara A, Yukihira D, Bamba T, Fukusaki E, Arita M.
- Journal Title
  
  Frontiers in Genetics
  
  Volume : 63(18) Pages : 471-471
- DOI
  10.3389/fgene.2014.00471
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06557, KAKENHI-PROJECT-25871136
[Journal Article] MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis.2015
- Author(s)
  Hiroshi Tsugawa, Tomas Cajka, Tobias Kind, Yan Ma, Brendan Higgins, Kazutaka Ikeda, Mitsuhiro Kanazawa, Jean VanderGheynst, Oliver Fiehn, Masanori Arita
- Journal Title
  
  Nat Methods
  
  Volume : 12 Pages : 523-526
- DOI
  10.1038/nmeth.3393
- Peer Reviewed / Int'l Joint Research / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01812, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898
[Journal Article] Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry2014
- Author(s)
  Hiroshi Tsugawa, Yuki Tsujimoto, Kuniyo Sugitate, Norihiro Sakui, Shin Nishiumi, Takeshi Bamba, Eiichiro Fukusaki
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume : 117 Pages : 122-128
- DOI
  10.1016/j.jbiosc.2013.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] Different-batch metabolome analysis of Saccharomyces cerevisiae based on gas chromatography/mass spectrometry2014
- Author(s)
  Naoki Kawase, Hiroshi Tsugawa, Takeshi Bamba, Eiichiro Fukusaki
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume : 117 Pages : 248-255
- DOI
  10.1016/j.jbiosc.2013.07.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] MRMPROBS suite for metabolomics using large-scale MRM assays2014
- Author(s)
  Hiroshi Tsugawa, Mitsuhiro Kanazawa, Atsushi Ogiwara, Masanori Arita
- Journal Title
  
  Bioinformatics
  
  Volume : 30 Pages : 2379-2380
- DOI
  10.1093/bioinformatics/btu203
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry2014
- Author(s)
  Hiroshi Tsugawa, Yuki Tsujimoto, Kuniyo Sugitate, Norihiro Sakui, Shin Nishiumi, Takeshi Bamba, Eiichiro Fukusaki
- Journal Title
  
  Journal of bioscience and bioengineering
  
  Volume : 117 Pages : 122-128
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25871136
[Journal Article] Method for Assessing the Statistical Significance of Mass Spectral Similarities Using Basic Local Alignment Search Tool Statistics2013
- Author(s)
  松田史生、福崎英一郎
- Journal Title
  
  Analytical Chemistry
  
  Volume : 85 Pages : 8291-8217
- DOI
  10.1021/ac401564v
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25820400, KAKENHI-PROJECT-25871136
[Journal Article] MRMPROBS: Data Assessment and Metabolite Identification Tool for Large-scale MRM-based Widely Targeted Metabolomics2013
- Author(s)
  Tsugawa, H., Arita, M., Kanazawa, M., Ogiwara, A., Bamba, T., Fukusaki, E
- Journal Title
  
  Anal. Chem.
  
  Volume : 85(10) Pages : 5191-5199
- DOI
  10.1021/ac400515s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23686120, KAKENHI-PROJECT-24656503, KAKENHI-PROJECT-25871136
[Presentation] MRMPROBS: Data Assessment and Metabolite Identification Tool for Large-scale MRM-based Widely Targeted Metabolomics2013
- Author(s)
  Hiroshi Tsugawa
- Organizer
  American Society for Mass Spectrometry Annual Conference
- Place of Presentation
  ミネアポリス，USA
- Data Source
  KAKENHI-PROJECT-25871136
[Presentation] MRMPROBS: Multiple reaction monitoringを用いた定量メタボロミクス研究に資するピーク評価方法ならびにデータ解析ソフトウェアの開発2013
- Author(s)
  津川裕司
- Organizer
  第８回メタボロームシンポジウム
- Place of Presentation
  九州大学, 福岡市東区馬出３丁目１番１号
- Data Source
  KAKENHI-PROJECT-25871136
[Presentation] MRMPROBS：Multiple reaction monitoringを用いたワイドターゲットメタボローム解析のためのピーク評価法ならびにデータ解析ソフトウェアの開発2013
- Author(s)
  津川裕司
- Organizer
  第61回質量分析討論会
- Place of Presentation
  つくば国際会議場, 茨城県つくば市竹園２丁目２０－３
- Data Source
  KAKENHI-PROJECT-25871136

1. 中林亮 (30586160)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
2. MATSUDA Fumio

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
3. BAMBA Takeshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
4. FUKUSAKI Eiichiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
5. 有田正規

# of Collaborated Projects : 0results

# of Collaborated Products : 5results
6. 有田誠

# of Collaborated Projects : 0results

# of Collaborated Products : 5results
7. 和泉自泰

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

TSUGAWA Hiroshi 津川 裕司

Research Projects

Research Products

Co-Researchers

Illuminating new biological mechanisms by multiomics approach with mass spectrometry cheminformaticsPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying epimetabolites and its elucidations by computational mass spectrometryPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of next generation untaregeted metabolomics methodologies using LC-MS/MSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a data processing system for LC-QqQ/MS based metabolomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Advances in computational metabolomics and databases deepen the understanding of metabolisms2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrated strategy for unknown EI-MS identification using quality control calibration curve, multivariate analysis, EI-MS spectral database, and retention index prediction.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The importance of bioinformatics for connecting data-driven lipidomics and biological insights2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrogen rearrangement rules: computational MS/MS fragmentation and structure elucidation using MS-FINDER software2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MRM-DIFF: data processing strategy for differential analysis in large scale MRM-based lipidomics studies2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Different-batch metabolome analysis of Saccharomyces cerevisiae based on gas chromatography/mass spectrometry2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MRMPROBS suite for metabolomics using large-scale MRM assays2014

Author(s)

TSUGAWA Hiroshi 津川裕司

[Presentation] MRMPROBS: Multiple reaction monitoringを用いた定量メタボロミクス研究に資するピーク評価方法ならびにデータ解析ソフトウェアの開発2013

[Presentation] MRMPROBS：Multiple reaction monitoringを用いたワイドターゲットメタボローム解析のためのピーク評価法ならびにデータ解析ソフトウェアの開発2013