Nakajima Koichi 中嶋弘一

… Alternative Names

NAKAJIMA Koichi 中嶋弘一

中島弘一ナカジマコウイチ

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Researcher Number	00227787
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪公立大学, 大学院医学研究科, 特別研究員 2021: 大阪市立大学, 大学院医学研究科, 特別研究員 2020: 大阪市立大学, 大学院医学研究科, 特任教授 2015 – 2019: 大阪市立大学, 大学院医学研究科, 教授 2013 – 2014: 大阪市立大学, 医学(系)研究科(研究院), 教授 … More 2011: 大阪市立大学, 大学院医学研究科, 教授 2007 – 2011: 大阪市立大学, 大学院・医学研究科, 教授 2001: 大阪市立大学, 大学院・医学研究科, 教授 1998 – 2000: 大阪市立大学, 医学部, 教授 1992 – 1997: 大阪大学, 医学部, 助教授 1991: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Immunology / General medical chemistry / Biological Sciences / Hematology Except Principal Investigator General medical chemistry / Basic Section 53010:Gastroenterology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Epidemiology and preventive medicine / Bio-related chemistry / Pathological medical chemistry / Chemistry related to living body
Keywords	Principal Investigator STAT3 / IL-6 / gp130 / IL-6応答領域 / シグナル伝達 / H7-感受性キナーゼ / JAK / pYXXQモチーフ / H7感受性キナーゼ / STAT … More / stat3 gene / stat3遺伝子 / Ras / 転写伸長 / 転写活性 / c-myc遺伝子 / 細胞周期 / 増殖・分化 / CDKインヒビターp19^<INK4D> / Ras伝達路 / SHP-2 / ETSファミリー / プロモーター / junB / 転写活性化 / 細胞内シグナル伝達 / 制御キナーゼ / コンフォメーション / タンパク相互作用 / 構造解析 / CRM1非依存的核外輸送 / pS727-依存的非活性化機序 / pY705-SH2 結合 / 活性化／非活性化サイクル / 核外輸送 / チロシン脱リン酸化 / 非活性化機序 / 核外輸送系 / コンフォメーション変化 / pS727 / pY705-SH2 構造 / knock-in mouse / pYXXQ motif / an H7-sensitive STAT3 kinase / c-myc gene / ノックインマウス / c-myc / IL-6 response element / CDK inhibitor, p19^<INK4D> / Growth and Differentiation / MAP kinase / CDKインヒビター / Stat5 / Jakキナーゼ / Stat3 / 増殖・分化・生存 / MAPキナーゼ / アナログ感受性CDK9変異体 / CDK9 / STAT3修飾 / STAT3リン酸化修飾 / 超転写伸長複合体 / CTDキナーゼ / 転写制御機序 / チロシンフォスファターゼ / キナーゼ / RNAポリメラーゼ / クロマチン免疫沈降法 / 転写制御 / 蛋白複合体 / 転写開始 / H7-感受性キナーゼ群 / リン酸化 / 細胞増殖 / Stat3遺伝子 / 抗アポトーシス / JAKキナーゼ / Stat転写因子群 / 増殖分化生存 / 分化 / 増殖 / 細胞増殖分化 / Stat転写 / etsファミリー / Statファミリー / 転写因子 / IL-6シグナル伝達 / ATFファミリー / CREB / インターロイキン6 / cAMP応答領域(CRE) / Ets結合部位 / ILー6応答領域 / プロモ-タ- / JunB / ILー6 … More Except Principal Investigator シグナル伝達 / がん / 選択的スプライシング / スプライシング制御因子 / S1-1 nuclear body / 活動度の自己調節機構 / 細胞分裂機構とRBM10 / RBM10遺伝子変異と疾病 / splicing regulator / RBM10/S1-1 / サイトカイン / RBM10 / インターロイキン6 / junB / 多発性骨髄腫 / 膵臓ガン患者の延命 / 延命を可能にする遺伝子変異 / RBM10のWikipedia改訂 / RBM10の総説執筆 / Wikipediaの全面改訂 / 当該遺伝子の総説執筆 / Splicing 制御 / 原著論文 IJMSに発表 / RBM10 遺伝子総説 / Wikipedia (英語版)全面改訂 / 総説 RBM10 / 精子形成 / 男性不妊症 / 精子形成不全 / 臨床疫学 / バイオマーカー / エクソソーム / 潜在性結核感染症 / miRNA / 結核感染症 / RBM10異常に由来する疾病群 / RBM10異常と細胞病態 / RBM10標的転写産物の網羅的同定 / X-linked 遺伝子 / 細胞内RBM10レベルの制御機構 / RBM10によるG2/M期arrest / 細胞分裂制御 / RBM10活性の制御機構 / RBM10異常による細胞病態と疾病 / RBM10が関わる細胞内過程 / RBM10標的遺伝子の同定 / RBM10制御下の遺伝子群 / RBM10/ S1-1 / C2H2 Zn finger / 細胞内情報伝達 / 細胞老化 / アイソフォーム1と2 / 抗がん剤 / Fas / スプラーシング制御 / S1-1 nuclear body targeting sequence / 核移行配列 / がん危険遺伝子 / アポトーシス関連遺伝子 / 転写制御 / スプライシング制御 / S1-1 / プロセシング / RNA / 癌 / 分子標的療法 / プロテオーム / 免疫 / 細胞医科学 / 転写因子 / Statファミリー / Jakキナーゼ / チロシンキナーゼ / 受容体 / JunB / ストロ-マ細胞 / インタ-ロイキン6 Less

Elucidation of the pathogenesis of azoospermia caused by deficiency of the RNA-binding protein RBM10 and exploration of treatment methods
- Principal Investigator
  
  Kunimoto Hiroyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Mutations for life lengthening of pancreatic cancer patients: mechanism and proposed theory for practice
- Principal Investigator
  
  INOUE Akira
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Fate determination of nuclear STAT3Principal Investigator
- Principal Investigator
  
  Nakajima Koichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
Identification biomarker of small RNA and its physiological and pathological role in immune response to Tuberculosis and latent TB infection
- Principal Investigator
  
  Zhao Hong
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Osaka City University
Unified elucidation of cell pathology of various diseases stemming from alternative splicing regulator RBM10
- Principal Investigator
  
  Inoue Akira
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka City University
Role of STAT3 in cytokine-induced senescence
- Principal Investigator
  
  Kojima Hirotada
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka City University
The splicing factor and diseases caused by its anomaly
- Principal Investigator
  
  INOUE Akira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka City University
Mechanism of cytokine-induced cellular senescence
- Principal Investigator
  
  KOJIMA Hirotada
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
Study on the mechanisms of STAT3-dependent transcriptional elongationPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
Molecular mechanism for the regulation of NLK
- Principal Investigator
  
  KOJIMA Hirotada
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
細胞質、核内でのSTAT3転写因子活性制御シグナルの解明とがん抑制法開発Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
STAT転写因子活性制御機構の解明とがん抑制法への応用Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
STAT転写因子群による細胞増殖誘導機構の解明Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka City University
STAT3の細胞増殖とがん化における役割の解明Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka City University
Elucidation of the regulation mechanisms of the STAT3 signaling pathway in the immune cellsPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Koichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka City University
Statシグナル伝達系調節機構とStatの癌化における役割の解明Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Stat転写因子群の増殖・分化における役割Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Mechanisms of IL-6 function determining growth and differentiation of lymphocytes and marophagesPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Koichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
シグナル伝達性転写因子群の活性化機序と癌化における役割Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
リンパ球増殖分化におけるIL-6作用機序Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
シグナル伝達性転写因子郡の活性化機序と癌化における役割Principal Investigator
- Principal Investigator
  
  中島弘一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
リンパ球増殖分化におけるIL-6作用機序Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
IL-6による発癌機構の解析
- Principal Investigator
  
  平野俊夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
IL-6による発癌機構の解析
- Principal Investigator
  
  平野俊夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
JunB遺伝子発現に至るIL-6シグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
JunB,TISll遺伝子発現に至るILー6シグナル伝達経路の解明Principal Investigator
- Principal Investigator
  
  中嶋弘一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
ILー6による発癌機構の解析
- Principal Investigator
  
  平野俊夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University

All 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation Book Patent

[Book] Tumor Dormancy and Cellular Quiescence and Senescence, Cancer, and Noncancer Pathologies : Interleukin-6 Induces Premature Senescence Involving the STAT3 and Insulin-Like Growth Factor-Binding Protein 52013
- Author(s)
  Kojima H, Kunimoto H, Inoue T, Nakajima K.Aging
- Publisher
  (in press)
- Data Source
  KAKENHI-PROJECT-21590316
[Book] 医学のあゆみJAK-STATの標準経路と非標準経路モデル2010
- Author(s)
  中嶋弘一、小島裕正
- Data Source
  KAKENHI-PROJECT-21590317
[Journal Article] Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological Significance2021
- Author(s)
  Wang Ling-Yu、Xiao Sheng-Jun、Kunimoto Hiroyuki、Tokunaga Kazuaki、Kojima Hirotada、Kimura Masatsugu、Yamamoto Takahiro、Yamamoto Naoki、Zhao Hong、Nishio Koji、Tani Tokio、Nakajima Koichi、Sunami Kishiko、Inoue Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10526-10526
- DOI
  10.3390/ijms221910526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08327, KAKENHI-PROJECT-19K08378, KAKENHI-PROJECT-21K06174, KAKENHI-PROJECT-21K07557
[Journal Article] RBM10 regulates centriole duplication in HepG2 cells by ectopically assembling PLK4‐STIL complexes in the nucleus2020
- Author(s)
  Kunimoto Hiroyuki、Inoue Akira、Kojima Hirotada、Yang Junhao、Zhao Hong、Tsuruta Daisuke、Nakajima Koichi
- Journal Title
  
  Genes to Cells
  
  Volume: 25(2) Issue: 2 Pages: 100-110
- DOI
  10.1111/gtc.12741
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08327, KAKENHI-PROJECT-19K08378
[Journal Article] Phospho-Ser727 triggers a multistep inactivation of STAT3 by rapid dissociation of pY705?SH2 through C-terminal tail modulation2020
- Author(s)
  Yang Junhao、Kunimoto Hiroyuki、Katayama Bumpei、Zhao Hong、Shiromizu Takashi、Wang Lingyu、Ozawa Toshiyuki、Tomonaga Takeshi、Tsuruta Daisuke、Nakajima Koichi
- Journal Title
  
  International Immunology
  
  Volume: 32(2) Issue: 2 Pages: 73-88
- DOI
  10.1093/intimm/dxz061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08327, KAKENHI-PROJECT-17K08639
[Journal Article] Targeting of RBM10 to S1-1 Nuclear Bodies: Targeting Sequences and its Biological Significance2019
- Author(s)
  L.-Y. Wang, S.-J. Xiao, H. Kunimoto, K. Tokunaga, H. Kojima, M. Kimura, T. Yamamoto, N.Yamamoto, Z. Hong, K. Nishio, H Yamane, T. Tani, K. Nakajima, H. Iguchi, and A. Inoue
- Journal Title
  
  bioRkiv
  
  Volume: -
- DOI
  10.1101/516831
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05569
[Journal Article] The Molecular Basis of Chemical Chaperone Therapy for Oculocutaneous Albinism Type 1A2018
- Author(s)
  Ayako Teramae, Yui Kobayashi, Hiroyuki Kunimoto, Koichi Nakajima, Tamio Suzuki, Daisuke Tsuruta and Kazuyoshi Fukai
- Journal Title
  
  J Invest Dermatol
  
  Volume: 139 Issue: 5 Pages: 1143-1149
- DOI
  10.1016/j.jid.2018.10.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10170, KAKENHI-PROJECT-19K08327
[Journal Article] Deacetylation of the mitotic checkpoint protein BubR1 at lysine 250 by SIRT2 and subsequent effects on BubR1 degradation during the prometaphase/anaphase transition.2014
- Author(s)
  Suematsu T, Li Y, Kojima H, Nakajima K, Oshimura M, Inoue T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 3 Pages: 588-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460392
[Journal Article] IL-6-STAT3 signaling and premature senescence.2013
- Author(s)
  Kojima H, Inoue T, Kunimoto H, Nakajima K.
- Journal Title
  
  JAKSTAT
  
  Volume: 2 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460392
[Journal Article] The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts2012
- Author(s)
  Hirotada Kojima, Hiroyuki Kunimoto, Toshiaki Inoue and Koichi Nakajima
- Journal Title
  
  Cell Cycle
  
  Volume: 11 Pages: 730-739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590317
[Journal Article] Phospho-Ser727 of STAT3 regulates STAT3 activity by enhancing dephosphorylation of phospho-Tyr705 largely through TC452012
- Author(s)
  Ryohei Wakahara, Hiroyuki Kunimoto, Kanae Tanino, Hirotada Kojima, Akira Inoue, Haruo Shintaku and Koichi Nakajima
- Journal Title
  
  Genes Cells
  
  Volume: 17 Pages: 132-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590317
[Journal Article] The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts2012
- Author(s)
  Kojima H, Kunimoto H, Inoue T, Nakajima K
- Journal Title
  
  Cell Cycle
  
  Volume: 11 Issue: 4 Pages: 730-739
- DOI
  10.4161/cc.11.4.19172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590316, KAKENHI-PROJECT-23570005
[Journal Article] Phospho-Ser727 of STAT3 regulates STAT3 activity by enhancing dephosphory-lation of phospho-Tyr705 largely through TC452011
- Author(s)
  Ryohei Wakahara, Hiroyuki Kunimoto, Kanae Tanino, Hirotada Kojima, Akira Inoue, Haruo Shintaku and Koichi Nakajima
- Journal Title
  
  Genes to Cells
  
  Volume: 17 Issue: 2 Pages: 132-145
- DOI
  10.1111/j.1365-2443.2011.01575.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550162, KAKENHI-PROJECT-21590316, KAKENHI-PROJECT-21590317
[Journal Article] Identification of functional domains and novel binding partners of STIM proteins2011
- Author(s)
  Saitoh N, Oritani K, Saito K, Yokota T, Ichii M, Sudo T, Fujita N, Nakajima K, Okada M, Kanakura Y
- Journal Title
  
  J Cell Biochem
  
  Volume: 112 Issue: 1 Pages: 147-156
- DOI
  10.1002/jcb.22910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590316, KAKENHI-PROJECT-21591241, KAKENHI-PROJECT-23591387
[Journal Article] Identification of functional domains and novel binding partners of STIM proteins.2011
- Author(s)
  Saitoh N, Oritani K, Saito K, Yokota T, Ichii M, Sudo T, Fujita N, Nakajima K, Okada M, Kanakura Y.
- Journal Title
  
  J Cell Biochem.
  
  Volume: 112 Pages: 147-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590316
[Journal Article] Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia2010
- Author(s)
  Imanishi H, Tsuruta D, , Tateishi C, Sugawara K, Paus R, Tsuji T, Ishii M, Ikeda K, Kunimoto H, Nakajima K, Jones JC, Kobayashi H
- Journal Title
  
  J Dermatol Sci
  
  Volume: 58 Issue: 1 Pages: 43-54
- DOI
  10.1016/j.jdermsci.2010.02.005
- NAID
  10027400358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590316
[Journal Article] 【サイトカインと疾患 : あらたな病態モデルから治療へ】サイトカインシグナル伝達機構 JAK-STATの標準経路と非標準経路モデル2010
- Author(s)
  中嶋弘一, 小島裕正
- Journal Title
  
  医学のあゆみ
  
  Volume: 234(5) Pages: 325-330
- Data Source
  KAKENHI-PROJECT-21590316
[Journal Article] GANP suppresses the arginine methyltransferase PRMT5 regulating IL-4-mediated STAT6-signaling to IgE production in B cells2009
- Author(s)
  Igarashi H, Kuwahara K, Yoshida M, Xing Y, Maeda K, Nakajima K and Sakaguchi N
- Journal Title
  
  Mol Immunol
  
  Volume: 6 Issue: 6 Pages: 1031-41
- DOI
  10.1016/j.molimm.2008.08.272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590316
[Journal Article] GANP suppresses the arginine methyltransferase PRMT5 regulatingIL-4-mediated STAT6-signaling to IgE production in B cells2009
- Author(s)
  Igarashi H, Kuwahara K, Yoshida M, Xing Y, Maeda K, Nakajima K, Sakaguchi N.
- Journal Title
  
  Molecular Immunology 46 (6)
  
  Pages: 1031-1041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590284
[Patent] ＳＴＡＴ３非活性化促進化合物及びそのスクリーニング方法2019
- Inventor(s)
  中嶋　弘一
- Industrial Property Rights Holder
  中嶋　弘一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-076400
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08639
[Presentation] Tetramer-based model of STAT3 activation-inactivation2019
- Author(s)
  Lingyu Wang, Hong Zhao, Junhao Yang, Hiroyuki Kunimoto, Koichi Nakajima
- Organizer
  第48回　日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08327
[Presentation] Tetramer-based model of STAT3 activation-inactivation2019
- Author(s)
  Wang Lingyu, Zhao Hong, Yang Junhao, Kunimoto Hiroyuki, Nakajima Koichi
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K08639
[Presentation] RBM10はHepG2において中心小体複製に関わる新規の調節因子である2019
- Author(s)
  國本浩之, 井上晃, 趙虹, 中嶋弘一
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08327
[Presentation] RBM10はHepG2において中心小体複製に関わる新規の調節因子である.2019
- Author(s)
  國本浩之, 井上晃, 趙虹, 中嶋弘一
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08378
[Presentation] Dissociation of STAT3 C-terminal tail from its own SH2 is critical for phosphoSer727-dependent STAT3 inactivation2018
- Author(s)
  Yang Junhao, Kunimoto Hiroyuki, Zhao Hong, Wang Lingyu, Nakajima Koichi
- Organizer
  日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K08639
[Presentation] RBM10による中心小体形成の制御機序について2017
- Author(s)
  國本浩之、趙虹、井上晃、中嶋弘一
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K05569
[Presentation] RBM10の活動度を制御する自己調節機構： S1-1 NB-targeting2017
- Author(s)
  井上晃, 國本浩之, 王凌宇, 肖勝軍, 小島裕正, 山本隆博, 山本直樹, 木村政継, 徳永和明, 谷時雄, 中嶋弘一, 井口広義
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K05569
[Presentation] Fate decision of activated STAT3 for nuclear accumulation or export through regulated multiple conformational changes.2017
- Author(s)
  Yang Junhao, Kunimoto Hiroyuki, Katayama Bumpei, Wang Lingyu, Zhao Hong, Ozawa Toshiyuki, Tsuruta Daisuke, Nakajima Koichi
- Organizer
  5th Annual Meeting of the International Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08639
[Presentation] RBM10過剰発現による増殖抑制機序の解析2016
- Author(s)
  國本浩之、趙虹、井上晃、中嶋弘一
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K05569
[Presentation] The role of STAT3 C-terminal region in the regulation of STAT3 stability2014
- Author(s)
  Yang J, Kojima H, Kunimoto H, Nakano S, Nakajima K.
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館 (京都府・京都市)
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25460392
[Presentation] Phospho-Ser727 of STAT3 shortens the duration of STAT3 activity by enhancing the dephosphorylation of pY705 through nuclear TC452011
- Author(s)
  Wakahara R, Kunimoto H, Kojima H, Nakajima K
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉市
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] Phospho-Ser727nof STAT3 shortens the duration of STAT3 by enhancing the dephosphorylation of pY705 through nuclear TC452011
- Author(s)
  Ryouhei Wakahara, Hiroyuki Kunimoto, Hirotada Kojima and Koichi Nakajima
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21590317
[Presentation] Phospho-Ser727 of STAT3 shortens the duration of STAT3 activity by enhancing the dephosphorylation of pY705 through nuclear TC452011
- Author(s)
  Wakahara R, Kunimoto H, Kojima H, Nakajima K
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉市)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] Prolonged stimulation of gp130 leads to premature senescence of human diploid fibroblasts2010
- Author(s)
  Kojima, H., Kunimoto H., Nakajima K.
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21590317
[Presentation] gp130-Stat3 signaling induces premature cellular senescence2010
- Author(s)
  Kojima H, Kunimoto H, Nakajima K
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] Prolonged stimulation of gp130 leads to premature senescence of human diploid fibroblasts2010
- Author(s)
  Kojima H, Kunimoto H, Nakajima K
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] gp130-Stat3 signaling induces premature cellular senescence2010
- Author(s)
  小島裕正, 國本浩之, 中嶋弘一
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] S1-1 nuclear bodyの動態と細胞の遺伝子発現活性の相関2010
- Author(s)
  井上晃、木村成継、山根英雄、中嶋弘一
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590317
[Presentation] Prolonged stimulation of gp130 leads to premature senescence of human diploid fibroblasts2010
- Author(s)
  Kojima H, Kunimoto H, Nakajima K
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] Prolonged stimulation of gp130 leads to premature senescence of human diploid fibroblasts2010
- Author(s)
  Hirotada Kojima, Hiroyuki Kunimoto, and Koichi Nakajima
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21590317
[Presentation] Prolonged stimulation of gp130 leads to premature senescence of human diploid fibroblasts2009
- Author(s)
  Kojima H, Kunimoto H, Nakajima K
- Organizer
  第32回日本分子生物学会年会, パシフィコ横浜
- Place of Presentation
  神奈川県
- Year and Date
  2009-12-17
- Data Source
  KAKENHI-PROJECT-19590284
[Presentation] Prolonged stimulation of gp130 leads to premature senescence of human diploid fibroblasts2009
- Author(s)
  Kojima H, Kunimoto H, Nakajima K
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2009-12-17
- Data Source
  KAKENHI-PROJECT-21590316
[Presentation] gp130を介した細胞老化誘導機構の解析2008
- Author(s)
  Kojima H, Nozawa T, Kunimoto H, Nakajima K
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同年会, 神戸ポートアイランド
- Place of Presentation
  兵庫県
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590284

1. KOJIMA Hirotada (40336772)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
2. 平野俊夫 (40136718)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. INOUE Akira (50109857)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. Kunimoto Hiroyuki (80372853)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
5. 松田正 (20212219)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. Zhao Hong (10596183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 改正恒康 (60224325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 山本直樹 (70312296)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 井上敏昭 (80305573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 村上善基 (00397556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 濱崎考史 (40619798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUKAI Kazuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakajima Koichi 中嶋 弘一

NAKAJIMA Koichi 中嶋 弘一

中島 弘一 ナカジマ コウイチ

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Fate determination of nuclear STAT3Principal Investigator

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Study on the mechanisms of STAT3-dependent transcriptional elongationPrincipal Investigator

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細胞質、核内でのSTAT3転写因子活性制御シグナルの解明とがん抑制法開発Principal Investigator

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STAT転写因子活性制御機構の解明とがん抑制法への応用Principal Investigator

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STAT転写因子群による細胞増殖誘導機構の解明Principal Investigator

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STAT3の細胞増殖とがん化における役割の解明Principal Investigator

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Nakajima Koichi 中嶋弘一

NAKAJIMA Koichi 中嶋弘一

中島弘一ナカジマコウイチ