SASAMURA Hiroyuki 篠村裕之

Researcher Number	00235293
Other IDs
Affiliation (based on the past Project Information) *help	2013: 慶應義塾大学, 医学部, 特任准教授 2012 – 2013: 慶應義塾大学, 医学部, 准教授 2011: 慶應義塾大学, 医学部, 特任准教授 2009 – 2010: Keio University, 医学部, 准教授 2003 – 2008: 慶應義塾大学, 医学部, 講師 1998 – 2002: 慶應義塾大学, 医学部, 助手 1999: 慶応義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine Except Principal Investigator Endocrinology / Kidney internal medicine
Keywords	Principal Investigator 腎障害 / 受容体 / アンジオテンシン / 高血圧 / Nephrotic syndrome / Renal iniury / Gelatinase / Collagenase / ネフローゼ症候群 / ゲラチナーゼ … More / コラゲナーゼ / Fibrosis / Kidney / Proteoglycan / Biglycan / リモデリング / 線維化 / 腎臓 / プロテオグリカン / バイグリカン / Extracellular Matrix / Receptor / Angiotensin / 細胞外基質 / G PROTEIN / RECEPTOR / ANGIOTENSIN / G蛋白質 / 食塩 / 塩分 / 糸球体硬化 / レニンーアンジオテンシン系 / 退行 … More Except Principal Investigator FoxO1 / Fox01 / iPS細胞 / 胆汁酸 / FOXO1 / メタボリックシンドローム / 心血管ホルモン / 細胞代謝 / 抗加齢医学 / 内分泌学 / 腎臓病 / 高血圧 Less

Analysis of salt memory in hypertension and its molecular mechanismPrincipal Investigator
- Principal Investigator
  
  SASAMURA Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Regulation of cell-metabolism by cardiovascular hormones and the comprehensive application to metabolic syndrome.
- Principal Investigator
  
  ITOH Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Keio University
Regression of hypertension : molecular analysis and epigenetic assessmentPrincipal Investigator
- Principal Investigator
  
  SASAMURA Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Transient treatment with ARB can suppress the development of hypertension and nephropathy
- Principal Investigator
  
  ISHIGURO Kimiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Role of collagenases and gelatinases in renal injury and their, therapeutic applicationsPrincipal Investigator
- Principal Investigator
  
  SASAMURA Hiroyuki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Mechanisms of attenuation of renal injury in biglycan transgenic micePrincipal Investigator
- Principal Investigator
  
  SASAMURA Hiroyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Investigation of effects of angiotensin type 2 receptors on extracellular matrix synthesis for renal therapyPrincipal Investigator
- Principal Investigator
  
  SASAMURA Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
INVESTIGATION OF SIGNAL TRANSDUCTION AND ANTI-PROLIPERATIVE ACTIONS OF ANGIOTENSIN II TYPE 2 PECEPTORPrincipal Investigator
- Principal Investigator
  
  SASAMURA Hiroyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation Patent

[Journal Article] Comparison between angiotensin-converting enzyme inhibitors andangiotensin receptor blockers on the risk of stroke recurrence and longitudinal progression of white matter lesions and silent brain infarcts on MRI (CEREBRAL study): rationale design and methodology2013
- Author(s)
  S. Yamano, H. Sasamura et al.
- Journal Title
  
  International Journal of Stroke
  
  Volume: 7 Pages: 1499-1501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591225
[Journal Article] Feasibility of regression of hypertension using contemporary antihypertensive agents2013
- Author(s)
  H. Sasamura, H. Nakaya, S. Julius, N Tomotusugu, Y Satoh, F Takahashi, M Takeuchi, M Murakami, M Ryuzaki , H. Itoh
- Journal Title
  
  Am J Hypertension
  
  Volume: 26 Pages: 1381-1383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591225
[Journal Article] Feasibility of regression of hypertension using contemporary antihypertensive agents2013
- Author(s)
  H. Sasamura, H. Nakaya et al.
- Journal Title
  
  American Journal of Hypertension
  
  Volume: 26 Pages: 1381-1388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591225
[Journal Article] Regression of atherosclerosis in apolipoprotein E-deficient mice is feasible using high-dose angiotensin receptor blocker candesartan2012
- Author(s)
  K. Hayashi, H. Sasamura, T. Azegami, H. Itoh
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 19 Pages: 736-746
- NAID
  130004444629
- URL
  https://www.jstage.jst.go.jp/article/jat/19/8/19_12534/_article:
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591225
[Journal Article] Vaccination against the angiotensin type I receptor for the prevention of L-NAME induced nephropathy2012
- Author(s)
  Tatsuhiko Azegami, Hiroyuki Sasamura, Kaori Hayashi, Hiroshi Itoh
- Journal Title
  
  Hyertension Research
  
  Volume: (印刷中) Issue: 5 Pages: 492-499
- DOI
  10.1038/hr.2011.212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890205, KAKENHI-PROJECT-23591225
[Journal Article] Management of prehypertension (review)2011
- Author(s)
  H. Sasamura
- Journal Title
  
  Current Hypertension Reviews
  
  Volume: 7 Pages: 118-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591225
[Journal Article] Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-induced albuminuria and glomerulosclerosis.2010
- Author(s)
  Y.Sakamaki, H.Sasamura, et al.
- Journal Title
  
  Nephron
  
  Volume: 115 Pages: 22-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2.2010
- Author(s)
  K.Hayashi, H.Sasamura, et al.
- Journal Title
  
  Kidney International
  
  Volume: 78 Pages: 69-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-induced albuminuria and glomerulosclerosis.2010
- Author(s)
  Y.Sakamaki, H.Sasamura, K.Hayashi, K.Ishiguro, H.Takaishi, H.Okada, J.M.D'Armiento, T.Saruta, H.Itoh
- Journal Title
  
  Nephron 115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2.2010
- Author(s)
  K.Hayashi, H.Sasamura, K.Ishiguro, Y.Sakamaki, T.Azegami, H.Itoh
- Journal Title
  
  Kidney International 78
  
  Pages: 69-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Prevention and regression of hypertension: role of renal microvascular protection.2009
- Author(s)
  H.Sasamura, K.Hayashi, K.Ishiguro, H.Nakaya, T.Saruta, H.Itoh
- Journal Title
  
  Hypertension Research 32
  
  Pages: 658-664
- NAID
  10025164652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] 'Pulse' treatment with angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension2009
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sakamaki, Hiroshi Itoh
- Journal Title
  
  Hypertension Jan
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] 'Pulse' treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension2009
- Author(s)
  K.Ishiguro, H.Sasamura, et al.
- Journal Title
  
  Hypertension 53
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Prevention and regression of hypertension : role of renal microvascular protection2009
- Author(s)
  H.Sasamura, K.Hayashi, et al.
- Journal Title
  
  Hypertension Research 32
  
  Pages: 658-664
- NAID
  10025164652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Pulse treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.2009
- Author(s)
  K.Ishiguro, K.Hayashi, H.Sasamura, Y.Sakamaki, H.Itoh
- Journal Title
  
  Hypertension 53
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] 'Pulse' treatment with angiotensin blocker reverses renal arteriolar ypertrophy and regresses hypertension.2009
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sakamaki, Hiroshi Itoh.
- Journal Title
  
  Hypertension
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] Pulse treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension2009
- Author(s)
  K. Ishiguro, K. Hayashi, H. Sasamura, Y. Sakamaki, H Itoh
- Journal Title
  
  Hypertension
  
  Volume: 53 Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390286
[Journal Article] Short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study : rationale and studydesign2008
- Author(s)
  H. Sasamura, H. Nakaya, et al.
- Journal Title
  
  Hypertension Research 31
  
  Pages: 1843-1849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy2008
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, and Hiroshi Itoh
- Journal Title
  
  Nephron 109
  
  Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] Short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study : rationale and study design.2008
- Author(s)
  H.Sasamura, H.Nakaya, T.Takebayashi, Y.Sato, K.Ishiguro, M.Ryuzaki, M.Murakami, S.Julius, H.Itoh
- Journal Title
  
  Hypertension Research 31
  
  Pages: 1843-1849
- NAID
  10024827357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy.2008
- Author(s)
  K.Ishiguro, H.Sasamura, Y.Sakamaki, K.Hayashi, H.Itoh
- Journal Title
  
  Nephron 109
  
  Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Differential effects of transient treatment of spontaneously hyperten sive rats with various antihypertensive agents on the subsequent de velopment of diabetic nephropathy2008
- Author(s)
  K. Ishiguro, H, Sasamura, et al.
- Journal Title
  
  Nephron 109
  
  Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590984
[Journal Article] Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy2008
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, and Hiroshi Itoh.
- Journal Title
  
  Nephron 109
  
  Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] Developmental activity of the renin-angiotensin system during the 'critical period' modulates later L-NAME-induced hypertension and renal injury2007
- Author(s)
  K., Ishiguro, H., Sasamura, et. al.
- Journal Title
  
  Hypertens Res 30
  
  Pages: 63-75
- NAID
  10018831485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Developmental activity of the renin-angiotensin system during the"critical period"modulates later L-NAME induced hypertension and renal injury2007
- Author(s)
  K. Ishiguro, H. Sasamura, et. al.
- Journal Title
  
  Hypertension Research 30
  
  Pages: 63-75
- NAID
  10018831485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Hiroshi Itoh, and Takao Saruta
- Journal Title
  
  Hypertens. Res. 30
  
  Pages: 63-75
- NAID
  10018831485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] Developmental activity of the renin-angiotensin system during the"critical period"modulates later L-NAME-induced hypertension and renal injury2007
- Author(s)
  K.Ishiguro, H.Sasamura, et. al.
- Journal Title
  
  Hypertension Research 30
  
  Pages: 63-75
- NAID
  10018831485
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Comparison of health costs associated with treatment of hypertension with a calcium channel blocker and angiotensin-converting enzyme inhibitor in the United States and Japan2006
- Author(s)
  Y.Sakamaki, H.Sasamura, et. al.
- Journal Title
  
  Hypertension Research 29
  
  Pages: 333-338
- NAID
  10018399317
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Effects of the angiotensin receptor blocker candesartan on arterial stiffness and markers of extracellular matrix metabolism in patients with essential hypertension2006
- Author(s)
  H.Sasamura et al.
- Journal Title
  
  Clinical and Experimental Hypertension 28(5)
  
  Pages: 511-520
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Comparison of health costs associated with treatment of hypertension with a calcium channel blocker and angiotensin-converting enzyme inhibitor in the United States and Japan2006
- Author(s)
  Y.Sakamaki, H.Sasamura et al.
- Journal Title
  
  Hypertension Research 29(5)
  
  Pages: 333-338
- NAID
  10018399317
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Comparison of health costs associated with treatment of hypertension with a calcium channel blocker and angiotensin-converting enzyme inhibitor in the United States and Japan2006
- Author(s)
  Y., Sakamaki, H., Sasamura, et. al.
- Journal Title
  
  Hypertens Res 29
  
  Pages: 333-338
- NAID
  10018399317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Effects of the angiotensin receptor blocker candesartan on arterial stiffness and markers of extracellular matrix metabolism in patients with essential hypertension2006
- Author(s)
  H., Sasamura, et. al.
- Journal Title
  
  Clin Exp Hypertens 28
  
  Pages: 511-520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Matrix metalloproteinase(MMP) inhibition exacerbates albuminuria, renal dysfunction, and glomerular injury in adriamycin-induced experimental focal segmental glomerulosclerosis.2006
- Author(s)
  Y.Sakamaki, H.Sasamura et al.
- Journal Title
  
  Journal of the American Society of Nephrology 17
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Effects of the angiotensin receptor blocker candesartan on arterial stiffness and markers of extracellular matrix metabolism in patients with essential hypertension2006
- Author(s)
  H.Sasamura, et. al.
- Journal Title
  
  Clinical and Experimental Hypertension 28
  
  Pages: 511-520
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Extracellular matrix remodeling in hypertension2005
- Author(s)
  H.Sasamura et al.
- Journal Title
  
  Current Hypertension Reviews 1
  
  Pages: 51-60
- Data Source
  KAKENHI-PROJECT-17590844
[Journal Article] Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration.2004
- Author(s)
  Shimizu-Hirota R, Sasamura H et al.
- Journal Title
  
  Circulation Research 94
  
  Pages: 1067-1074
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration.2004
- Author(s)
  R.Shimizu-Hirota, H.Sasamura, M.Kuroda, B.Kobayashi, M.Hayashi, T.Saruta.
- Journal Title
  
  Circulation Research 94
  
  Pages: 1067-1074
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family.2004
- Author(s)
  R.Shimizu-Hirota, H.Sasamura, M.Kuroda, E.Kobayashi, T.Saruta.
- Journal Title
  
  FEBS Letters 563(1-3)
  
  Pages: 69-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family2004
- Author(s)
  Shimizu-Hirota R, Sasamura H et al.
- Journal Title
  
  FEBS Letters 563(1)
  
  Pages: 69-74
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Glomerular expression of biglycan and decorin and urinary levels of decorin in primary glomerular disease.2004
- Author(s)
  M.Kuroda, H.Sasamura, E.Kobayashi, R.Shimizu-Hirota, Y.Nakazato, M.Hayashi, T.Saruta.
- Journal Title
  
  Clinical Nephrology 61(1)
  
  Pages: 7-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Glomerular expression of biglycan and decorin and urinary levels of decorin in primary glomerular disease.2004
- Author(s)
  Kuroda M, Sasamura H et al.
- Journal Title
  
  Clinical Nephrology 61
  
  Pages: 7-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family.2004
- Author(s)
  Shimizu-Hirota R, Sasamura H et al.
- Journal Title
  
  FEBS Letters 563
  
  Pages: 69-74
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration2004
- Author(s)
  Shimizu-Hirota R, Sasamura H et al.
- Journal Title
  
  Circulation Research 94(8)
  
  Pages: 1067-1074
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Hepatocyte growth factor regulates proteoglycan synthesis in interstitial fibroblasts.2003
- Author(s)
  Kobayashi E, Sasamura H et al.
- Journal Title
  
  Kidney International 64
  
  Pages: 1179-1188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Hepatocyte growth factor regulates proteoglycan synthesis in interstitial fibroblasts.2003
- Author(s)
  E.Kobayashi, H.Sasamura, M.Mifune, R.Shimizu-Hirota, M.Kuroda, M.Hayashi, T.Saruta.
- Journal Title
  
  Kidney International 64
  
  Pages: 1179-1188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Glucocorticoid regulation of proteoglycan synthesis in mesangial cells.2002
- Author(s)
  Kuroda M, Sasamura H et al.
- Journal Title
  
  Kidney International 62
  
  Pages: 780-789
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Glucocorticoid regulation of proteoglycan synthesis in mesangial cells.2002
- Author(s)
  M.Kuroda, H.Sasamura, R.Shimizu-Hirota, M.Mifune, H.Nakaya, E.Kobayashi, M.Hayashi, T.Saruta.
- Journal Title
  
  Kidney International 62
  
  Pages: 780-789
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Prepubertal treatment with angiotensin receptor blocker causes partial attenuation of hypertension and renal damage in adult Dahl salt-sensitive rats.2002
- Author(s)
  H.Nakaya, H.Sasamura, M.Mifune, R.Shimizu-Hirota, M.Kuroda, M.Hayashi, T.Saruta.
- Journal Title
  
  Nephron 91
  
  Pages: 710-718
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Journal Article] Prepubertal treatment with angiotensin receptor blocker causes partial attenuation of hypertension and renal damage in adult Dahl salt-sensitive rats.2002
- Author(s)
  Nakaya H, Sasamura H et al.
- Journal Title
  
  Nephron 91
  
  Pages: 710-718
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571036
[Patent] 慢性腎臓病判定用血清マーカーおよびその検出方法、装置2009
- Inventor(s)
  篠村裕之、林香、伊藤裕、末松誠、曽我朋義
- Industrial Property Rights Holder
  篠村裕之、林香、伊藤裕、末松誠、曽我朋義
- Filing Date
  2009-08-17
- Data Source
  KAKENHI-PROJECT-21390286
[Presentation] Feasibility of regression of hypertension using an angiotensin receptor blocker2013
- Author(s)
  Hiroyuki Sasamura et al.
- Organizer
  23rd Scientific Meeting, European Society of Hypertension
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Studies on regression of hypertension2013
- Author(s)
  H. Sasamura
- Organizer
  2nd International conference on prehypertension and cardiometabolic syndrome
- Place of Presentation
  Barcelona
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Feasibility of regression of hypertension with an angiotensin receptor blocker2013
- Author(s)
  H. Sasamura, H. Nakaya, S. Julius, H. Itoh
- Organizer
  23^<rd> Scientific Meeting, European Society of Hypertension
- Place of Presentation
  Milan
- Year and Date
  2013-06-15
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] 高血圧発症における「塩分メモリー」の証明とその機序の検討2013
- Author(s)
  小口　英世、篠村　裕之,ら
- Organizer
  日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Cost-effectiveness analysis of amlodipine/atorvastatin single-pill therapy for patients with hypertension and hyperlipidemia2012
- Author(s)
  H. Nakaya, H. Sasamura, I. Saito, Y. Inoue, S. Kobayashi, T. Saruta, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Regression of atherosclerosis in apolipoprotein E-deficient mice is feasible using high-dose angiotensin receptor blocker2012
- Author(s)
  K. Hayashi, H. Sasamura, T. Azegami, H. Oguchi, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Effects of brief exposure to a high-salt diet in Dahl salt-sensitive rats : evidence for'salt memory'during hypertension development2012
- Author(s)
  K. Ishiguro, H. Sasamura, H. Oguchi, M. Nakamura, K. Hayashi, T. Azegami, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Vaccination against the angiotensin II type 1 receptor prevents L-NAME-induced nephropathy in SHR2012
- Author(s)
  T. Azegami, H. Sasamura, K. Hayashi, H. Oguchi, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] 高血圧モデル動物における「塩分メモリー」の検討2012
- Author(s)
  小口英世、篠村裕之、石黒喜美子、中村真理、林　香、畔上達彦、伊藤裕
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Effects of brief exposure to a high-salt diet in Dahl salt-sensitive rats: evidence for ‘salt memory’ during hypertension development2012
- Author(s)
  K. Ishiguro, H. Sasamura, H. Oguchi, M. Nakamura, K. Hayashi, T. Azegami, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Efficacy of vaccination against the angiotensin II type 1 receptor and ApoB 100 for the prevention of atherosclerosis2012
- Author(s)
  T. Azegami, H. Sasamura, K. Hayashi, H. Oguchi, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Salt memory of hypertension in spontaneously hypertensive rats (SHR) requires both sodium and chloride ions2012
- Author(s)
  H. Oguchi, H. Sasamura, K. Ishiguro, M. Nakamura, K. Hayashi, T. Azegami, H. Itoh
- Organizer
  24th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Dahl食塩感受性高血圧ラットに対する一過性塩分負荷の効果の検討2011
- Author(s)
  石黒　喜美子、篠村　裕之、他
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  栃木県総合文化センター（栃木県）
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] アンジオテンシン受容体拮抗薬(ARB)高用量投与による動脈硬化の退縮とその機序の検討2011
- Author(s)
  林　香、篠村裕之、他
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  栃木県総合文化センター（栃木県）
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Is regression of hypertension feasible? The rationale and design of the STAR CAST study2011
- Author(s)
  H. Sasamura
- Organizer
  1^<st> International conference on prehypertension and cardiometabolic syndrome
- Place of Presentation
  Vienna
- Year and Date
  2011-02-26
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] レニンーアンジオテンシン系ワクチンの高血圧、蛋白尿予防効果とその機序の検討2011
- Author(s)
  畔上　達彦、篠村　裕之、他
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  栃木県総合文化センター（栃木県）
- Data Source
  KAKENHI-PROJECT-23591225
[Presentation] Prevention of hypertension and renal injury by a renin-angiotensin system (RAS) vaccine in L-NAME-treated spontaneously hypertensive rats (SHR).2010
- Author(s)
  T.Azegami, H.Sasamura, K.Hayashi, K.Ishiguro, H.Itoh
- Organizer
  23^<rd> Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] The short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study : rationale and interim report.2010
- Author(s)
  H.Sasamura, H.Nakaya, S.Julius, Y.Sato, H.Itoh
- Organizer
  20^<th> European Meeting of Hypertension
- Place of Presentation
  Oslo
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] 'Pulse' treatment with high-dose angiotensin receptor blocker (ARB) causes regression of hypertension in SHRmcr-cp rats with metabolic syndrome.2010
- Author(s)
  K.Ishiguro, H.Sasamura, Y.Sakamaki, K.Hayashi, H.Itoh
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Transient treatment with high-dose angiotensin receptor blocker (ARB) causes regression of hypertension in a rat model of metabolic syndrome (SHRmcr-cp).2010
- Author(s)
  K.Ishiguro, H.Sasamura, et al.
- Organizer
  23rd International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Short-term treatment with high-dose angiotensin blocker (ARB) induces sustained regression of adriamycin-induced glomerulosclerosis and albuminuria.2010
- Author(s)
  K.Hayashi, H.Sasamura, K.Ishiguro, Y.Sakamaki, T.Azegami, H.Itoh
- Organizer
  23^<rd> Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Role of extracellular matrix (ECM) remodeling in high-dose angiotensin blocker-induced regression of hypertension and glomerulosclerosis.2010
- Author(s)
  K.Hayashi, H.Sasamura, K.Ishiguro, Y.Sakamaki, T.Azegami, H.Itoh
- Organizer
  6^<th> International Congress of Pathophysiology
- Place of Presentation
  Montreal
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Metabolomic profiling as a tool for the assessment of patients with chronic kidney disease.2010
- Author(s)
  K.Hayashi, H.Sasamura, T.Hishiki, M.Suematsu, S.Ikeda, T.Soga, H.Itoh
- Organizer
  International Society of Nephrology Nexus Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Treatment with high-dose angiotensin blocker regresses adriamycin-induced glomerulosclerosis and albuminuria.2010
- Author(s)
  K.Hayashi, H.Sasamura, K.Ishiguro, Y.Sakamaki, T.Azegami, H.Itoh
- Organizer
  International Society of Nephrology Nexus Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Efficacy of renin-angiotensin system (RAS) vaccine for prevention of proteinuria and renal injury in spontaneously hypertensive rats (SHR).2010
- Author(s)
  T.Azegami, H.Sasamura, K.Hayashi, K.Ishiguro, H.Itoh
- Organizer
  6^<th> International Congress of Pathophysiology
- Place of Presentation
  Montreal
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Prevention of proteinuria and renal injury by a renin-angiotensin system (RAS) vaccine in spontaneously hypertensive rats (SHR).2010
- Author(s)
  T.Azegami, H.Sasamura, K.Hayashi, K.Ishiguro, H.Itoh
- Organizer
  International Society of Nephrology Nexus Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Assessment of potential risk factors for cardiovascular disease in patients with chronic kidney disease (CKD) by metabolome analysis.2010
- Author(s)
  K.Hayashi, H.Sasamura, T.Hishiki, M.Suematsu, S.Ikeda, T.Soga, H.Itoh
- Organizer
  23^<rd> Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Microarray analysis of mechanisms involved in the prevention and regression of hypertension by angiotensin receptor blocker (ARB) in spontaneously hypertensive rats.2010
- Author(s)
  H.Sasamura, K.Hayashi, K.Ishiguro, Y.Sakamaki, T.Azegami, H.Itoh
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Short-term treatment with high-dose angiotensin blocker (ARB) induces sustained regression of adriamycin-induced glomerulosclerosis and albuminuria.2010
- Author(s)
  K.Hayashi, H.Sasamura, et al.
- Organizer
  23rd International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] The short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study : design and preliminary report.2010
- Author(s)
  H.Sasamura, H.Nakaya, S.Julius, Y.Sato, H.Itoh
- Organizer
  23^<rd> Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Transient treatment with high-dose angiotensin receptor blocker (ARB) causes regression of hypertension in a rat model of metabolic syndrome (SHRmcr-cp).2010
- Author(s)
  K.Ishiguro, H.Sasamura, Y.Sakamaki, K.Hayashi, T Azegami, H.Itoh
- Organizer
  23^<rd> Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] メタボリックシンドローム(MetS)モデル動物に対する「ARB高用量パルス投与」の効果の検討2009
- Author(s)
  石黒喜美子、篠村裕之, 他
- Organizer
  第32回日本高血圧学会総会
- Place of Presentation
  大津
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] ARB高用量一過性投与は高血圧モデル動物において高血圧の退行(regression)と心血管肥大の抑制をもたらず2009
- Author(s)
  石黒喜美子、篠村裕之, 他
- Organizer
  第45回高血圧関連疾患モデル学会
- Place of Presentation
  東京
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] 'Pulse' treatment with high-dose angiotensin receptor blocker (ARB) causes prominent regression of established glomerulosclerotic lesions in mice.2008
- Author(s)
  K.Hayashi, H.Sasamura, K.Ishiguro, Y.Sakamaki, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Effects of 'pulse' treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and microvascular remodeling in spontaneously hypertensive rats (SHR).2008
- Author(s)
  K.Ishiguro, K.Hayashi, H.Sasamura, Y.Sakamaki, T.Saruta, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] 高血圧発症抑制とのアンジオテンシン抑制薬の「一過性パルス投与」による高血圧の退行(regression)の検討2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、伊藤裕
- Organizer
  アンジオテンシンカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Effects of' pulse 'treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and renal microvascular remodeling in spontaneously hypertensive rats (SHR)2008
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sakamaki, and Hiroshi Itoh
- Organizer
  Effects of' pulse 'treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and renal microvascular remodeling in spontaneously hypertensive rats (SHR)
- Place of Presentation
  Berlin
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] ARB'一過性高用量パルス投与'による高血圧の退行(regression)療法の開発2008
- Author(s)
  石黒喜美子,林香,篠村裕之,坂巻裕介,伊藤裕
- Organizer
  第44回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  出雲
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Matrix metalloproteinase-9 (MMP-9) deletion suppresses the development of glomerulosclerosis in mice by a blood pressureand oxidative stress-independent mechanism.2008
- Author(s)
  Y.Sakamaki, H.Sasamura, K.Kshiguro, K.Hayashi, Y.Okada, T.Saruta, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Transient prepubertal exposure to an ARB or aldosterone antagonist suppresses the subsequent development of diabetic nephropathy2008
- Author(s)
  K. Ishiguro, H. Sasamura, et al.
- Organizer
  22^n International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Microarray analysis of vascular and renal mechanisms involved in suppression of hypertension development by prehypertensive treatment in spontaneously hypertensive rats (SHR).2008
- Author(s)
  K.Hayashi, K.Ishiguro, H.Sasamura, Y.Sakamaki, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] ARB高用量パルス投与は高血圧モデル動物において高血圧の著明な退行(regression)とともに心血管肥大の抑制をもたらす2008
- Author(s)
  石黒喜美子,林香,篠村裕之,坂巻裕介,伊藤裕
- Organizer
  第12回心血管内分泌学会学術総会
- Place of Presentation
  熊本
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] 高血圧発症後のACE阻害薬・ARB「一過性パルス療法」による高血圧の退行(regression)の検討2008
- Author(s)
  石黒喜美子,篠村裕之,坂巻裕介,林香,伊藤裕,
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] メタボリックシンドローム(MetS)モデルラットにおける'アンジオテンシン受容体拮抗薬(ARB)一過性パルス投与'による血圧・肥満・インスリ抵抗性体質の退行(regression)2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] メタボリックシンドローム(MetS)モデルラットにおける'アンジオテンシン受容体拮抗薬(ARB)一過性パルス投与'による血圧・肥満・インスリン抵抗性体質の退行(regression)2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study : rationale and study design2008
- Author(s)
  H. Sasamura, H. Nakaya, et al.
- Organizer
  22^n International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Comparison of costs between angiotensin receptor blocker (ARB) and calcium channel blocker (CCB) in hypertensive patients with high cardiovascular risks and analysis of the effects of new-onset diabetes, from the CASE-J Trial.2008
- Author(s)
  H.Nakaya, H.Sasamura, Y.Sakamaki, S.Ikeda, Y.Sato, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Effects of 'pulse' treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and renal microvascular remodeling in spontaneously hypertensive rats (SHR)2008
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sa kamaki, and Hiroshi Itoh
- Organizer
  The 22nd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] アンジオテンシン受容体拮抗薬およびアルドステロン拮抗薬の早期一過性投与による糖尿病性腎症発症抑制効果の比較検討2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study : rationale and study design.2008
- Author(s)
  H.Sasamura, H.Nakaya, T.Takebayashi, Y.Sato, K.Ishiguro, M.Ryuzaki, M.Murakami, S.Julius, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] Transient prepubertal exposure to an angiotensin receptor blocker or aldosterone antagonist suppresses the development of nephropathy in streptozotocin-induced diabetic hypertensive rats.2008
- Author(s)
  K.Ishiguro, H.Sasamura, Y.Sakamaki, K.Hayashi, T.Saruta, H.Itoh
- Organizer
  22nd Scientific Meeting, International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20590984
[Presentation] 高血圧発症後のACE阻害薬・ARB 「一過性パルス療法」による高血圧の退行(regression)の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、猿田享男、伊藤裕
- Organizer
  日本腎臓学会
- Place of Presentation
  浜松
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] レニンーアンジオテンシン系阻害薬「一過性パルス療法」による高血圧の退行(regression)の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、伊藤裕
- Organizer
  日本内分泌学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] レニンーアンジオテンシン系抑制薬の「一過性パルス投与」による高血圧退行療法(regression therapy)の開発とカルシウム桔抗薬との比較検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、伊藤裕
- Organizer
  日本高血圧学会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Transient exposure to angiotensin receptor blocker (ARB) during the 'critical period'inhibits the later development of nephropathy in streptozotocin-induced diabetic hypertensive rats2007
- Author(s)
  K. Ishiguro, H. Sasamura, et. al.
- Organizer
  40th Annual Meeting, American Society of Nephrology
- Place of Presentation
  San Francisco
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-17590844
[Presentation] Hiroshi Itoh Effects of Transient Exposure to Angiotensin or Aldosterone Antagonist During the 'Critical Period' on the Later Development of Nephropathy in Streptozotocin-induced Diabetic Rats2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, Takao Saruta
- Organizer
  Hiroshi Itoh Effects of Transient Exposure to Angiotensin or Aldosterone Antagonist During the 'Critical Period' on the Later Development of Nephropathy in Streptozotocin-induced Diabetic Rats
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Hiroshi Itoh Use ofTransient 'Pulse' Therapy with High-Dose Antihypertensive Agents to Induce Regression of Established Hypertension in Spontaneously Hypertensive Rats2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, Takao Saruta
- Organizer
  American Society of Nephrology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Effects of matrix metalloproteinase-9(MMP-9)deletion on progression of albuminuria and glomerular injury in adriamycin-induced experimental focal segmental glomerulosclerosis2007
- Author(s)
  Y.Sakamaki, H.Sasamura, et. al.
- Organizer
  40th Annual Meeting, American Society of Nephrology
- Place of Presentation
  San Francisco
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590844
[Presentation] レニンーアンジオテンシン系抑制薬の「一過性パルス投与」による高血圧退行療法(regression therapy)の開発とカルシウム拮抗薬との比較検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、伊藤裕
- Organizer
  日本高血圧学会学術総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] se of transient'pulse'therapy with high-dose antihypertensive agents to induceregression of established hypertension in spontaneously hypertensive rats2007
- Author(s)
  K. Ishiguro, H. Sasamura, et. al.
- Organizer
  40th Annual Meeting, American Society of Nephrology
- Place of Presentation
  San Francisco
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-17590844
[Presentation] アンジオテンシン受容体拮抗薬の早期一過性投与による糖尿病性腎症発症抑制効果の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  心血管内分泌学会学術総会
- Place of Presentation
  品川
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] レニンーアンジオテンシン系阻害薬「一過性パルス療法」による高血圧の退行(regression)の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、伊藤裕
- Organizer
  日本内分泌学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Effects of Transient Exposure to Angiotensin or Aldosterone Ant agonist During the 'Critical Period'on the Later Development of Nephropathy in Streptozotocin-induced Diabetic Rats2007
- Author(s)
  Kimiko Ishiguro, Hirojmki Sasamura, Yusiike Sakamaki, Kaori Hayashi, Takao Saruta, Hiroshi Itoh
- Organizer
  Americaa Society of Nephrology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] 高血圧発症後のACE阻害薬・ARB「一過性パルス療法」による高血圧の退行(regression)の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、猿田享男、伊藤裕
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] アンジオテンシン受容体措抗薬の早期一過性投与による糖尿病性腎症発症抑制効果の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  心血管内分泌学会
- Place of Presentation
  品川
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] VEffects of matrix metalloproteinase-9(MMP-9)deletion on progression of albuminuria and glomerular injury in adriamycin-induced experimental focal segmental glomerulosclerosis2007
- Author(s)
  Y., Sakamaki, H., Sasamura, et. al.
- Organizer
  40th Annual Meeting ASN
- Place of Presentation
  San Francisco
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590844
[Presentation] Use of TVaimient 'Pulse' Therapy with High-Dose Antihypertensi ve Agents to Induce Regression of Established Hypertension in Spontaneously HTOertensive Rats。2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, Takao Saruta, Hiroshi Itoh
- Organizer
  American Society of Nephrology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578

1. ITOH Hiroshi (40252457)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
2. HAYASHI Matsuhiko (60129608)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. ISHIGURO Kimiko (20424161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
4. HAYASHI Kaori (60445294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
5. NAKAE Jun (00344573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. WATANABE Mitsuhiro (10450842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SONE Masakatsu (40437207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ICHIHARA Atsuhiro (60203105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIBATA Hirotaka (20245484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WAKINO Shu (50265823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MIYASHITA Kazutoshi (50378759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NISHIMOTO Ikuo (80180652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OKADA Yasunori (00115221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小林絵美 (00317116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 黒田真理 (40306692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAMURA Hiroyuki 篠村 裕之

Research Projects

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Co-Researchers

Analysis of salt memory in hypertension and its molecular mechanismPrincipal Investigator

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Regulation of cell-metabolism by cardiovascular hormones and the comprehensive application to metabolic syndrome.

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Regression of hypertension : molecular analysis and epigenetic assessmentPrincipal Investigator

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Transient treatment with ARB can suppress the development of hypertension and nephropathy

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Role of collagenases and gelatinases in renal injury and their, therapeutic applicationsPrincipal Investigator

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Mechanisms of attenuation of renal injury in biglycan transgenic micePrincipal Investigator

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Investigation of effects of angiotensin type 2 receptors on extracellular matrix synthesis for renal therapyPrincipal Investigator

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INVESTIGATION OF SIGNAL TRANSDUCTION AND ANTI-PROLIPERATIVE ACTIONS OF ANGIOTENSIN II TYPE 2 PECEPTORPrincipal Investigator

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[Journal Article] Comparison between angiotensin-converting enzyme inhibitors andangiotensin receptor blockers on the risk of stroke recurrence and longitudinal progression of white matter lesions and silent brain infarcts on MRI (CEREBRAL study): rationale design and methodology2013

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[Journal Article] Feasibility of regression of hypertension using contemporary antihypertensive agents2013

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[Journal Article] Feasibility of regression of hypertension using contemporary antihypertensive agents2013

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[Journal Article] Regression of atherosclerosis in apolipoprotein E-deficient mice is feasible using high-dose angiotensin receptor blocker candesartan2012

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NAID

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[Journal Article] Vaccination against the angiotensin type I receptor for the prevention of L-NAME induced nephropathy2012

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[Journal Article] Management of prehypertension (review)2011

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[Journal Article] Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-induced albuminuria and glomerulosclerosis.2010

SASAMURA Hiroyuki 篠村裕之