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Shimokawa Hiroaki  下川 宏明

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SHIMOKAWA Hiroaki  下川 宏明

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Researcher Number 00235681
Other IDs
Affiliation (Current) 2025: 国際医療福祉大学, 大学院, 副学長
Affiliation (based on the past Project Information) *help 2020 – 2021: 東北大学, 医学系研究科, 客員教授
2015 – 2019: 東北大学, 医学系研究科, 教授
2013 – 2015: 東北大学, 大学院医学系研究科, 教授
2011 – 2015: 東北大学, 医学(系)研究科(研究院), 教授
2012: 東北大学, 医学系研究科, 教授 … More
2012: 東北大学, 医学部, 教授
2007 – 2012: Tohoku University, Deparment of Cardiovascular Medicine, Professor
2007: 東北大学, 医学系研究科, 教授
2006: 東北大学, 大学院医学研究科, 教授
2006: Tohoku University, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授
2005 – 2006: 東北大学, 医学研究科, 教授
2005: Tohoku University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2000 – 2005: Kyushu Univ, Dept of Cardiovasc Med, Assoc Prof, 大学院・医学研究院, 助教授
2004: Kyushu Unviersity, faculty of Medical Sciences, Associate Professor, 大学院医学研究院, 助教授
2003 – 2004: Kyushu University, Associate professor, 医学研究院, 助教授
2002 – 2003: 九州大学, 大学院・医学研究院・循環器内科学, 助教授
2001: 九州大学, 医学研究院, 助教授
2001: Graduate school, Faculty of Pharmaceutical Sciences, Kyushu University, Associate Professor, 大学院・医学系研究院, 助教授
1999: Kyushu Univ. Graduate Sch., Dept. of Cardiovasc Med., Asso. Pro., 大学院・医学系研究科, 助教授
1994 – 1999: Kyushu University Assoc.Prof., 医学部, 助教授
1992 – 1994: 九州大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine / Cardiovascular medicine / Cardiovascular medicine / Basic Section 53020:Cardiology-related / General pharmacology / Medical pharmacy / Biological Sciences
Except Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine … More / Cardiovascular medicine / Biomedical engineering/Biological material science / General pharmacology / Medical and hospital managemen / Ophthalmology / Thoracic surgery / General pharmacology / Thoracic surgery / 応用薬理学・医療系薬学 / Biomedical engineering/Biological material science / Biological Sciences / Anesthesiology/Resuscitation studies / Hematology / Bioinformatics/Life informatics / Biological Sciences Less
Keywords
Principal Investigator
Rho-kinase / 動脈硬化 / 冠動脈攣縮 / 血管内皮 / サイトカイン / 炎症性サイトカイン / 虚血性心疾患 / 血管リモデリング / 一酸化窒素 / 炎症 … More / 肺高血圧症 / 内皮由来弛緩因子 / シグナル伝達 / 内皮由来過分極因子(EDHF) / 循環器・高血圧 / 心筋梗塞 / 低分子量G蛋白 / 過酸化水素 / superoxide anion / 大動脈瘤 / 臨床応用研究 / 分子血管学 / 循環器内科学 / 内科系臨床医学 / 医歯薬学 / Atherosclerosis / 再狭窄 / 冠攣縮性狭心症 / 虚血性心臓病 / マクロファージ / Rho-Kinase / nitric oxide / 心不全 / peroxynitrite / inflammatory cytokine / myocardial infarction / coronary thrombosis / coronary artery spasm / arteriosclerosis / ischemic heart disease / 冠動脈硬化 / 細胞増殖因子 / 冠動脈血栓 / バイオマーカー / スタチン / 酸化ストレス / 活性酸素 / 一酸化窒素合成酵素 / 免疫 / OX40L / 冠動脈 / 一酸化窒素(NO) / 血管外膜 / 遺伝子治療 / 胸部大動脈瘤 / 心血管・血液 / 薬理学一般 / 基礎医学 / ハイスループットスクリーニング / 基礎研究の臨床応用 / 創薬 / Microcirculation / Cardiovascular diseases / Nitric oxide / Hydrogen peroxide / Endothelium-derived hyperpolarizing factor / Endothelium-derived relaxing factors / eNOS欠損マウス / NOS欠損マウス / 内皮型NO合成酵素(eNOS) / 微小循環 / Rho-キナーゼ / 心血管病 / 一酸化水素 / 内皮由来過分極因子 / 内皮由来池緩因子 / international collaboration / genetic analysis / vasospastic angina / coronary vasospasm / 国際共同研究 / 遺伝子解析 / Nanodiagnosis / Functioning contrast medium / Nanomedicine / Nanocapsule / Nanotechnology / 冠動脈インターベンション / ナノカプセル(粒子) / バルーン傷害 / ナノ診断 / 機能化造影剤 / ナノ治療 / ナノカプセル / ナノテクノロジー / Pulmonary hypertension / Heart failure / Myocardial infarction / Restenosis / Cardiac hypertrophy / Vasospastic angina / 高血圧 / 狭心症 / Rho / 心肥大 / Oxidative stress / Angiotensin II / Arteriosclerosis / Inflammation / アンジオテンシンII / gene therapy / small G proteins / vascular remodeling / atherosclerosis. / cytokines / 冠攣縮 / adhesion molecules / パーオキシナイトライト / 好中球 / NO / 一酸化炭素 / 接着因子 / coronary spasm / 冠動撃縮 / inflammatory cytokines / 冠□縮 / 冠等縮 / Xa阻害薬 / 新規抗凝固薬 / Rhoキナーゼ / 平滑筋増殖 / 心血管疾患 / サイクロフィリンA / T細胞 / OX40L系 / OX40 / 免疫系細胞 / 一酸化窒素合成酵素(NOS) / 活性酵素 / Rho/Rho-kinase / 血管平滑筋 / 臓器関連 / メタボリックシンドローム / Rho/Rho-Kinase / 低酸素 / 骨髄置換 / CD4陽性T細胞 / 骨髄細胞 / catalase / 内皮型一酸化窒素合成酵素 / 退縮 / 内皮由来弛緩物質 / C型Na利尿ペプチド / 増殖因子 / チロシンキナーゼ / 魚油(fish oil) / エイコサペンタエン酸(EPA) … More
Except Principal Investigator
Rho-kinase / 一酸化窒素 / Rhoキナーゼ / 動脈硬化 / 循環器・高血圧 / 冠攣縮 / nitric oxide / 虚血性心疾患 / 血管新生 / 狭心症 / 血管内皮 / 心不全 / EDHF / 心筋梗塞 / 一酸化窒素合成酵素 / 活性酸素 / 遺伝子 / endothelial cell / セロトニン / 酸化ストレス / シグナル伝達 / 慢性心不全 / CTGF / TGF-beta / VEGF / 対外衝撃波 / PON1 / sympathetic nervous system / blood pressure / brain / 高血圧 / 脳 / Rho / 交感神経系 / 心拍数 / 血圧 / NF-kB / reactive oxygen species / 活性酸素種 / stent / 微細加工 / ステント / coronary vasospasm / サイトカイン / 冠動脈攣縮 / arteriosclerosis / gene transfer / Protein S / Gas6 / 組織因子 / アンジオテンシンII / アンジオテンシン変換酵素 / Nitric oxide / angina pectoris / 心筋虚血 / 血管内皮細胞 / アンギオテンシン変換酵素 / 冠循環 / 内皮細胞 / 冠攣縮性狭心症 / 薬剤溶出性ステント / 内科 / 循環器 / 急性心筋梗塞 / 内皮由来過分極因子 / 過酸化水素 / 低出力体外衝撃波治療 / 冠動脈ステント / 血栓 / 炎症 / 血管平滑筋 / トランスレーショナルリサーチ / メタボリック症候群 / 再生医療 / 冠微小血管 / 冠動脈 / 社会医学 / 臨床心臓病学 / 医療の質評価 / 後ろ向き観察研究 / 倫理委員会申請 / 血管機能異常 / 論文執筆 / 後ろ向き研究 / ポリマー / Vasa vassorum / 冠動脈過収縮反応 / 微小血管抵抗指数 / 血漿セロトニン / 冠微小循環障害 / バイオマーカー / 微小血管型狭心症 / non-pharmacological therapy / tachyarrhythmias / shock wave / 非薬物療法 / 不整脈 / Neovascularization / Hyalocytes / macular edema / Diabetic retinopathy / PDGF / 糖尿病網膜硝子体症 / 硝子体細胞 / 黄斑浮腫 / 糖尿病網膜症 / Cross-circulated system / Extracorporeal shock wave / Cardioplegia / 血液交叉灌流モデル / 血液交差灌流装置 / 体外衝撃波 / 心筋保護液 / metabolic syndrome / myocardial infarction / genetically engineered mice / nitric oxide synthase / 尿崩症 / 遺伝子改変 / マウス / 骨 / ノックアウト / メタボリックシンドローム / 遺伝子改変マウス / ROCK2 / Single nucleotide polymorphisms / Genetic analysis / Coronary vasospasm / Ischemic heart disease / SNP / 冠動脈縮攣 / SNPs / 遺伝解析 / norepinephrine / gene / heart rate / Reactive oxygen species / ノルエピネフリン / 交感神経活動 / scaffold / 光化学 / 内皮前駆細胞 / 生体適合化 / myocardial ischemia / coronary microvessel / 微小血管狭心症 / 微小循環 / Induction / Smooth muscle cell / Expression / Gene / Arteriosclerosis / Blood vessel / Nitric oxide synthase / 発言 / 誘導 / 平滑筋 / 発現 / 血管 / Chronic myocardial ischemia / Bone marrow cell / 慢性心筋虚血 / 骨髄細胞 / Hydrogen peroxide / EDRFs / Vascular endothelial cells / ギャップジャンクション / カタラーゼ / ブラジキニン / 内皮依存性過分極因子 / 内皮由来弛緩因子 / hypertension / signal transmission / 遺伝子導入 / transgenic mice / cytokine / heart failure / 活性酵素種 / 酸化窒素 / トランスジェニックマウス / failing myocardium / redox balance / reactive nitrogen species / spin-probe / free-radical / in vivo ESR-CT / 拡張型心筋症 / スピンプローブ / 病態解析 / 活性窒素 / スピントラップ / フリーラジカル / 生体ESR-CT / covered stent / 光加工 / エキシマ・レーザ / エキシマレーザー / genetic association / genetic linkage / genetic polymorphism / genome / schizophrenia / atopy / seasonal rhinitis / bronchial asthma / 連鎖解析 / 罹患同胞対法 / かもがや花粉症 / 精神分裂病 / 関連遺伝子 / 血清脂質異常 / 総合失調症 / 血清脂質 / 関連 / 連鎖 / 多型 / ゲノム / 統合失調症 / 花粉症 / アトピー / 気管支喘息 / regression / signal transduction / ischemic heart disease / coronary artery / arteriosclerossis / 動脈硬化の退縮 / Rhoーkinase / 退縮 / fibrosis / inflammation / MCP-1 / NF-κB / ケモカイン / monocyte chemoattractant protein-1 / 転写因子 / nitroglycerin / risk factor / vasopressors / epidural block / anesthesia / perioperative / coronany spasm / 麻酔薬 / プロポフォール / 交感神経 / 手術 / 昇圧薬 / ニトログリセリン / 周術期 / リスクファクター / 硬膜外麻酔 / 麻酔 / Vascular smooth muscle cells / Receptor tyrosine kinase / 血管平滑筋細胞 / Gas 6 / 動脈平滑筋細胞 / 受容体型チロシンキナーゼ / ProteinS / ENDOTHELIUM DERIVED NITRIC OXIDE / ENDOTHELIUM DEPENDENT VASODILATION / SEROTONIN / LUCIGENIN / (内皮由来)一酸化窒素 / 内皮由来一酸化窒素 / 内皮依存性血管弛緩反応 / ルシゲニン / xanthine dehydrogenase / superoxide dismutase / atherosclerosis / thrombosis / angiotensin II / angiotensin-converting enzyme / トロンビン / プラスミノーゲンアクチヴェーター阻害剤 / プラスミノーゲンアクチヴェーター / 一酸化窒素、 / 急性心筋梗塞症 / 冠動脈血栓症 / Microvessels / K channels / 内皮依存性弛緩反応 / 一酸化窒素(NO) / 内皮由来過分極因子(EDHF) / 微小血管 / NO / Kチャネル / angiotensin-converting enzyme inhibitor / papaverine / serotonin / coronary circulation / 内皮細胞由来一酸化窒素 / アンギオテンシン変換酵素阻害薬 / パパベリン / Thermal Balloon Catheter / Percutaneous Transvenous Coronary Angioplasty(PTCA) / Ischemic Heart Disease / 虚血清心臓病 / 加温式バルーンカテーテル / 経皮的冠動脈形成術 / 虚血性心臓病 / 内皮型一酸化窒素合成酵素 / コラーゲン代謝 / 内皮型一酸化合成酵素 / 右室線維化 / 右心不全 / 抗炎症作用 / 左室リモデリング / Rho-kinase活性 / 日内変動 / 血管過収縮反応 / 冠動脈疾患 / Vaso Vasorum / Vaso vasorum / 異常血管反応 / 薬剤溶出ステント / 心内心電図 / 導出心電図 / 12誘導心電図 / 導出18誘導心電図 / dominant frenquency / 周波数解析 / カテーテル治療 / 導出18誘導心電図 / 心電図 / 心房細動 / ストレス / 循器・高血圧 / 臨床 / 血管内皮機能 / アンジオテンシン受容体拮抗薬 / 内因性過酸化水素 / 冠血管予備能 / 冠微小循環 / 糖尿病 / 急性心不全 / 心血管病 / 急性冠症候群 / 肺高血圧症 / Rhoキナーゼ活性 / 血管反応性 / カルシウム拮抗薬 / 冠動脈スラント / 老化 / 心肥大 / 腎臓病 / 脂質代謝 / 高脂血症 / ノックアウトマウス / 生体分子 / 生理活性 / ケミカルバイオロジー / Rho-キナーゼ / 心室線維化 / 心筋拡張障害 / 拡張不全 / 再生医学 / 心機能 / 心臓発生 / FGF受容体 / 細胞タカルシウム濃度 / レトロウイルス / 細胞増殖因子 / 心筋細胞 / L-NMMA / L-NAME / ブタ / 内皮由来血管弛緩物質 / メチレンブルー / ヘモグロビン / NMMA / スライス標本 / L-arginine / nitnic oxide / サブスタンス-P / L-アルジニン / No Less
  • Research Projects

    (73 results)
  • Research Products

    (469 results)
  • Co-Researchers

    (129 People)
  •  Discovery of new etiologic molecules for thoracic aortic aneurysm and development of therapeutic strategies (early diagnosis / drug discovery)Principal Investigator

    • Principal Investigator
      Shimokawa Hiroaki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Tohoku University
  •  Explorateive research of biomarkers for coronary microvascular dysfunction in the patients with vasospastic angina

    • Principal Investigator
      Takahashi Jun
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  The effect of new generation drug-eluting stent on coronary vasomotion

    • Principal Investigator
      Tsuburaya Ryuji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  Functional analysis of novel cardiovascular protective factorPrincipal Investigator

    • Principal Investigator
      Shimokawa Hiroaki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Tohoku University
  •  Basic and clinical research on novel targets of pulmonary arterial hypertensionPrincipal Investigator

    • Principal Investigator
      Shimokawa Hiroaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  Nationwide database platform of cardiovascular diseases to measure quality indicator and develop predicting model

    • Principal Investigator
      Yasuda Satoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical and hospital managemen
    • Research Institution
      National Cardiovascular Center Research Institute
  •  新しいRho-kinase阻害薬による肺高血圧治療効果の検討Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  Circadian variation of Rho-kinase activity in circulating leukocytes of patients with vasospastic angina.

    • Principal Investigator
      Takahashi Jun
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  Extracorporeal low-energy shock wave therapy exerts anti-inflammatory effects in a rat model of acute myocardial infarction

    • Principal Investigator
      Ito Kenta
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  Right ventricular fibrosis/ Rho-kinase pathway in the development of right heart failure

    • Principal Investigator
      Fukumoto Yoshihiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kurume University
      Tohoku University
  •  The possibility of pleiotropic effects of Novel Oral Anticoagulants (NOAC) on Rho-kinase-cyclophilin A SystemPrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tohoku University
  •  Feasibility of Clininical Application of Synthesized 18-lead ECG in Atrial Fibrillation

    • Principal Investigator
      WEI DAMING
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      Tohoku University
  •  Impact of new generation drug-eluting stent on coronary vasomotion

    • Principal Investigator
      TSUBURAYA Ryuji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Rho-kinase activity in circulating neutrophils as a useful biomarker for diagnosis and disease activity assessment of vasospastic angina

    • Principal Investigator
      YASUDA Satoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      National Cardiovascular Center Research Institute
      Tohoku University
  •  The role of SmgGDS in the pleiotropic effects by statinsPrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Mechanism of Manifestation for Disturbance of Endocardial CoronaryMicrocirculation in Diabetes Mellitus by Measurements of Myocardial Radical Molecules

    • Principal Investigator
      YADA Toyotaka
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kawasaki Medical School
  •  Molecular mechanisms for NOSs-mediated responses in microvesselsPrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Establishment of the therapy of diastolic heart failure

    • Principal Investigator
      TAKAHASHI Jun
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Development of Novel Biomarker to Predict Cardiovascular Diseases

    • Principal Investigator
      FUKUMOTO Yoshihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Low-energy shock wave therapy for chronic heart failure

    • Principal Investigator
      ITO Kenta
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Signaling Functions of Reactive Oxygen Species

    • Principal Investigator
      AKAIKE Takaaki
    • Project Period (FY)
      2008 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      Kumamoto University
  •  The roleof H_20_2as an endothelium-derived relaxing factors (EDRFs)Principal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Elucidation of the significance of the nitric oxide synthase system in vivo by the use of mice lacking all nitric oxide synthases

    • Principal Investigator
      TSUTSUI Masato
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Molecular Mechanisms of Hyper-contraction of Drug-eluting Stent Implanted Coronary Arteries

    • Principal Investigator
      YASUDA Satoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  動脈硬化病変の進展および破綻における免疫系細胞活性化分子の役割の解明Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Molecular mechanisms for beneficial effects of low-energy shock wave therapy on myocardial ischemia

    • Principal Investigator
      ITO Kenta
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Long-term Inhibition of Rho-kinase Ameliorates Diastolic Heart Failure in Hypertensive Rats

    • Principal Investigator
      FUKUMOTO Yoshihiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  肺高血圧症の分子機構における免疫系細胞活性化分子の役割の解明Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  The shock wave as a new energy source of therapy for tachyarrhytmias

    • Principal Investigator
      KUMAGAI Koji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  Elucidation of roles of the nitric oxide synthase system on the basis of the development of mice lacing all nitric oxide synthase isoforms

    • Principal Investigator
      TSUTSUI Masato
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Improvement for myocardial preservation using extracorporeal shock wave

    • Principal Investigator
      TANOUE Yoshihisa
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      KYUSHU UNIVERCITY
  •  Investigation of the mechanisms of diabetic vitreoretinopathy and its pharmaceutical regulation

    • Principal Investigator
      HATA Yasuaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      KYUSHU UNIVERCITY
  •  冠攣縮性狭心症におけるRho-kinase活性化の機序の解明

    • Principal Investigator
      ITO Akira
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Experimental and Clinical Studies on the Significance of Endothelium-Derived Hyperpolarizing Factor (EDHF)Principal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
      Kyushu University
  •  Identification of genetic factors responsible for the pathogenesis of coronary vasospasm, that is more prevalent in the Japanese, resulting in ischemic heart disease, and characterization of its molecular mechanism.

    • Principal Investigator
      KOIKE George
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  High-performance Stent Technology

    • Principal Investigator
      MATSUDA Takehisa
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      KYUSHU UNIVERSITY
  •  International Collaboration Study on the Racial Difference in Coronary VasospasmPrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
      Kyushu University
  •  Role of reactive oxygen species within the vasomotor center of the brain in hypertension

    • Principal Investigator
      HIROOKA Yoshitaka
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  The development of bone marrow injection therapy for chronic myocardial ischemia

    • Principal Investigator
      HARADA Mine, 安井 久喬
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kyushu University
  •  Clarification of the mechanisms for vascular neuronal nitric oxide synthase expression

    • Principal Investigator
      TSUTSUI Masato
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Occupational and Environmental Health
  •  The Role of RhoA/Rho-kinase System in the Deterioration of Coronary Microcirculation in Ischemic Heart Disease

    • Principal Investigator
      ITO Akira, 毛利 正博
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Role of Rho/Rho-kinase-mediated pathway in the pathogenesls of atherosclerosisPrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki, 竹下 彰
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Development of Nanomedicine for the Treatment of Cardiovascular DiseasesPrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Elucidating the mechanism of heart failure using mouse model of dilated cardiomyopathy

    • Principal Investigator
      KUBOTA Toru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Role of Rho-kinase within the brain in abnormality of regulation of sympathetic nervous system in hypertension

    • Principal Investigator
      HIROOKA Yoshitaka
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Identification of endothelium-derived hyperpolarizing factor (EDHF) in human arteries.

    • Principal Investigator
      HIRAKAWA Yoji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  動脈硬化の分子機構におけるRho/Rho-kinase系の役割Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  内皮由来過分極因子(EDHF)は過酸化水素(H_2O_2)である可能性Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Identification of genes associated with bronchial asthtima, atopy, schizophrenia, and abnormal serum lipid profile

    • Principal Investigator
      ARINAMI Tadao
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Develop of High Performance Stents

    • Principal Investigator
      MATSUDA Takehisa
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kyushu University
  •  Basic and clinical studies on the role of inflammatory mechanisms in the pathogenesis ischemic heart diseasePrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Non-invasive evaluation of free radical reactions accompanied with induction and development of heart failure by in vivo ESR-CT

    • Principal Investigator
      UTSUMI Hideo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      KYUSHU UNIVERSITY
  •  血管リモデリングの成因における外膜の炎症性・増殖性機序の役割 遺伝子導入法を用いた検討Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  内皮由来過分極因子(EDHF)は内皮型一酸化窒素合成酵素由来である可能性-ノックアウトマウスを用いた検討-Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  MOLECULAR MECHANISMS OF CARDIOVASCULAR REMODELING INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE SYNTHESIS : ROLE OF NF-κB AND MCP-1

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  Development of intracellular therapy to induce a regression of coronary arteriosclerotic lesions

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  サイトカインによる血管リモデリングの分子機構におけるチロシンキナーゼの役割Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Experimental and Clinical Studies on the Role of Inflammatory Mechanisms in the Pathogenesis of Ischemic Heart DiseasePrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Horoaki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  Pathogenesis and treatment for anesthesia-related coronary arterial spasm

    • Principal Investigator
      HOKA Sumio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      KITASATO UNIVERSITY
  •  Development of Chronic Heart Failure Model Caused by Inflammatory Cytokines and Establishment of Prophylactic and Therapeutic Strategies for the Heart FailurePrincipal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  THE REGULATION OF ENDOTHELIAL CONSTITUTIVE NITRIC OXIDE SYNTHASE IN REGENERATED ENDOTHLIAL CELLS

    • Principal Investigator
      OHARA Yuichi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  Analysis of the effects of Gla-containing proteins and their receptors on the proliferation of vascular smooth muscle cells.

    • Principal Investigator
      TSUDA Hiroko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      KYUSHU UNIVERSITY
  •  Physiological and pathophysiological roles of endothelium-derived hyperpotarizing factor in the control of organ perfusion.

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY FACULTY OF MEDICINE
  •  The role of inflammatory mechanisms in the pathogenesis of ischemic heart disease. Basic and clinical studies.Principal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  molecular mechanisms of vascular thrombosis

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  ROLE OF MICROVASCULAR DISORDERS IN THE PATHOGENESIS OF MYOCARDIAL ISCHEMIA

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY FACULTY OF MEDICINE
  •  心不全における内皮依存性血管拡張能異常に関する研究

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  心臓発生過程および成熟心臓機能における線維芽細胞成長因子の役割の解明

    • Principal Investigator
      UENO Hikaru
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Role of Inflammatory Cytokines in the Development and Progression of Ischemic Heart Diseases-Experimental and Clinical Studies-Principal Investigator

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  心不全における内皮依存性血勘拡張能異常に関する研究

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  孤束核ニューロンのシナプス伝達における酸化窒素の役割に関する研究:特に逆行性精報伝達物質としての可能性について

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  エイコサペンタエン酸のサイトカイン動態に及ぼす影響に関する臨床的及び実験的研究Principal Investigator

    • Principal Investigator
      下川 宏明
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  A development and A basic research of New Thermal Balloon Catheter for Percutaneous Transvenous Coronary Angioplasty

    • Principal Investigator
      URABE Yoshitoshi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY

All 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent Other

  • [Book] 特集/SGLT2心腎連関 解説 Cyclophilin A  VoL.82 No.4, p.391~397.(2017年10月号)2017

    • Author(s)
      佐藤 公雄、下川 宏明.
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Book] Diagnosis and Treatment of Pulmonary Hypertension. From Bench to Bedside2017

    • Author(s)
      Satoh K, Sugimura K, Shimokawa H.
    • Total Pages
      236
    • Publisher
      Springer Nature, Singapore
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Book] Diagnosis and Treatment of Pulmonary Hypertension. From Bench to Bedside2017

    • Author(s)
      Satoh K, Sugimura K, Shimokawa H.
    • Total Pages
      236
    • Publisher
      Springer Nature, Singapore
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Book] 特集/SGLT2心腎連関 解説 Cyclophilin A(2017年10月号)2017

    • Author(s)
      佐藤 公雄、下川 宏明.
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Book] 「循環器内科」特集/循環器疾患と分子遺伝学 肺高血圧症の分子基盤2015

    • Author(s)
      佐藤 公雄、下川 宏明.
    • Total Pages
      8
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Book] 『酸化ストレスの医学 改訂第2版』(2014年8月) 心疾患と酸化ストレス2014

    • Author(s)
      佐藤 公雄、下川 宏明.
    • Total Pages
      7
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Book] The Pathogenesis of Vasospastic Angina. In : Kaski JC, Eslick GD, Bairey Merz CN (eds.), Chest Pain with Normal Coronary Arteries2013

    • Author(s)
      Yasuda S, Shimokawa H.
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Book] エリスロポエチンの血管内皮保護作用と血管恒常性維持機構2013

    • Author(s)
      佐藤公雄、下川宏明
    • Total Pages
      452
    • Publisher
      BIO Clinica.
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] 日本人の虚血性心疾患に関する基礎的・臨床的研究2013

    • Author(s)
      下川宏明
    • Publisher
      日本医師会雑誌141
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] The Pathogenesis of Vasospastic Angina. In: Kaski JC, Eslick GD, Bairey Merz CN (eds.)2013

    • Author(s)
      2.Yasuda S, Shimokawa H.
    • Total Pages
      12
    • Publisher
      Springer-Verlag, London, UK
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Book] エリスロポエチンの血管内皮保護作用と血管恒常性維持機構2013

    • Author(s)
      佐藤公雄、下川宏明
    • Publisher
      BIO Clinica.
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] エリスロポエチンの血管内皮保護作用と血管恒常性維持機構2013

    • Author(s)
      佐藤公雄、下川宏明
    • Publisher
      BIO Clinica.
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] Handb Exp Pharmacol2013

    • Author(s)
      Fukumoto Y, Shimokawa H
    • Total Pages
      576
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Book] 日本医師会雑誌 1412013

    • Author(s)
      下川宏明
    • Publisher
      日本医師会
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Book] 日本人の虚血性心疾患に関する基礎的・臨床的研究2013

    • Author(s)
      下川宏明
    • Publisher
      日本医師会雑誌
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] 日本人の虚血性心疾患に関 する基礎的・臨床的研究 (日本医師会医 学賞受賞記念総説)2013

    • Author(s)
      下川宏明
    • Publisher
      日本医師会雑 誌
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] H_2O_2が制御する血管弛緩反応2012

    • Author(s)
      下川宏明
    • Publisher
      日本薬理学雑誌.(日本薬理学会)
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] 肺高血圧診療の進歩をみる.特集にあたって2012

    • Author(s)
      下川宏明
    • Publisher
      Vascular Medicine
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] H2O2が制御する血管弛緩反応.2012

    • Author(s)
      下川宏明
    • Total Pages
      139
    • Publisher
      日本薬理学雑誌
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] 薬物治療無効、血行再建不適当患者に残された治療は何か?2012

    • Author(s)
      伊藤健太、下川宏明
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Book] H2O2が制御する血管弛緩反応.2012

    • Author(s)
      下川宏明
    • Total Pages
      232
    • Publisher
      日本薬理学雑誌
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] H2O2が制御する血管弛緩反応2012

    • Author(s)
      下川宏明
    • Total Pages
      232
    • Publisher
      日本薬理学雑誌
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] 内皮由来過分極因子の医学的意義.血栓と循環2012

    • Author(s)
      下川宏明、神戸茂雄
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] 大震災と循環器・呼吸器疾患(序文).呼吸と循環2012

    • Author(s)
      下川宏明
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] 肺高血圧診療の進歩をみる. 特集にあたって.Vascular Medicine2012

    • Author(s)
      下川宏明
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] 内皮由来過分極因子の医学的意義2012

    • Author(s)
      下川宏明、神戸茂雄
    • Publisher
      血栓と循環(メディカルレビュー社)
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] 大震災と循環器・呼吸器疾患(序文).呼吸と循環2012

    • Author(s)
      下川宏明
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] 内皮由来過分極因子の医学的意義.血栓と循環2012

    • Author(s)
      下川宏明、神戸茂雄
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] H_2O_2が制御する血管弛緩反応2012

    • Author(s)
      下川宏明
    • Publisher
      日本薬理学雑誌
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] 大震災と循環器・呼吸器疾患(序文)2012

    • Author(s)
      下川宏明
    • Publisher
      呼吸と循環(医学書院)
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] H_20_2が制御する血管弛緩反応.日本薬理学雑誌2012

    • Author(s)
      下川宏明
    • Publisher
      日本薬理学会
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] 肺高血圧症に対するRhoキナーゼ阻害薬の治療効果2011

    • Author(s)
      福本義弘、下川宏明
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Book] Annual Review 循環器2011

    • Author(s)
      福本義弘、下川宏明
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] 医学論文の書き方-Circulation Journal編集長からのアドバイス-心臓2011

    • Author(s)
      下川宏明
    • Publisher
      日本心臓財団・日本循環器学会
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] 医学論文の書き方.Circulation Journal編集長からのアドバイス-心臓2011

    • Author(s)
      下川宏明
    • Publisher
      日本心臓財団
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Book] Annual Review循環器2011

    • Author(s)
      福本義弘、下川宏明
    • Publisher
      肺高血圧症に対するRhoキナーゼ阻害薬の治療効果
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] Annual Review循環器2011

    • Author(s)
      福本義弘、下川宏明
    • Publisher
      肺高血圧症に対するRhoキナーゼ阻害薬の治療効果
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] 冠循環・心筋虚血の発生機序2010

    • Author(s)
      安田聡、下川宏明
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] 循環器疾患のサイエンス.東京(冠攣縮性狭心症)(小室一成編)2010

    • Author(s)
      安田聡, 下川宏明
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Book] 冠攣縮性狭心症(小室一成編)(循環器疾患のサイエンス)2010

    • Author(s)
      安田聡, 下川宏明
    • Total Pages
      236
    • Publisher
      東京:南山堂
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Book] 薬効群別副作用脂質異常症治療薬, 医薬品副作用ハンドブック第2版2010

    • Author(s)
      福本義弘、下川宏明
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Book] 冠循環・心筋虚血発生機序2010

    • Author(s)
      安田聡、下川宏明
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Book] 5章重症心不全を予防する10.メタボリックシンドロームを治す。重症心不全の予防と治療2009

    • Author(s)
      福本義弘、下川宏明
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Book] 冠攣縮性狭心症診療の現状と問題点2009

    • Author(s)
      安田聡, 小川久雄, 下川宏明
    • Total Pages
      6
    • Publisher
      日本循環器学会・循環器専門医
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Book] H2O2が制御する血管弛緩反応の分子機構(谷口直之(編))2009

    • Author(s)
      佐藤公雄、下川宏明
    • Publisher
      実験医学
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] Acta Physiologica(Endothelial dysfunction and vascular disease)2009

    • Author(s)
      Vanhoutte PM, Shimokawa H, et al.
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Book] Annual Review循環器2007(山口 徹、高本真一、中沢 誠、小室一成(編))(EDHF.)2007

    • Author(s)
      高木文, 下川宏明
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Book] 内科学(第9版) 欠陥の収縮弛緩と血圧調節機構2006

    • Author(s)
      下川宏明
    • Publisher
      朝倉書店(印刷中)
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Book] EBM循環器疾患の治療、冠攣縮性狭心症2005

    • Author(s)
      伊藤昭, 下川宏明
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Book] Rho・Rhoキナーゼ2004

    • Author(s)
      東みどり子, 下川宏明
    • Publisher
      メディカルレビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] PIM1 (Provirus Integration Site For Moloney Murine Leukemia Virus) as a Novel Biomarker and Therapeutic Target in Pulmonary Arterial Hypertension2020

    • Author(s)
      Satoh K, Kikuchi N, Shimokawa H.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology

      Volume: 40 Issue: 3 Pages: 500-502

    • DOI

      10.1161/atvbaha.120.313975

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-18K08094
  • [Journal Article] Beneficial effects of riociguat on hemodynamic responses to exercise in CTEPH patients after balloon pulmonary angioplasty - A randomized controlled study2020

    • Author(s)
      Aoki T, Tatebe S, Shimokawa H et al.
    • Journal Title

      Int J Cardiol Heart Vasc .

      Volume: 29 Pages: 100579-100579

    • DOI

      10.1016/j.ijcha.2020.100579

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08531, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-20K07776, KAKENHI-PROJECT-19H03646
  • [Journal Article] Identification of the Novel Variants in Patients With Chronic Thromboembolic Pulmonary Hypertension2020

    • Author(s)
      Yaoita N, Satoh K, Tatebe S, Yasuda S, Shimokawa H et al.
    • Journal Title

      J Am Heart Assoc .

      Volume: 9 Issue: 21 Pages: 1-12

    • DOI

      10.1161/jaha.120.015902

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08531, KAKENHI-PROJECT-19K11847, KAKENHI-PROJECT-19H03646, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-18K08094, KAKENHI-PROJECT-19H03647, KAKENHI-PROJECT-21K19469
  • [Journal Article] Sex differences in hemodynamic responses and long-term survival to optimal medical therapy in patients with pulmonary arterial hypertension.2018

    • Author(s)
      Kozu K, Sugimura K, Aoki T, Tatebe S, Yamamoto S, Yaoita N, Shimizu T, Nochioka K, Sato H, Konno R, Satoh K, Miyata S, Shimokawa H.
    • Journal Title

      Heart Vessels.

      Volume: in press Issue: 8 Pages: 939-947

    • DOI

      10.1007/s00380-018-1140-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-14F04902, KAKENHI-PROJECT-16K15198, KAKENHI-PROJECT-16K00039, KAKENHI-PROJECT-16K09414, KAKENHI-PROJECT-17K15982
  • [Journal Article] Selenoprotein P promotes vascular smooth muscle cell proliferation and pulmonary hypertension -A possible novel therapeutic target-2018

    • Author(s)
      Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Md. Elias Al-Mamun, Mohammad Abdul Hai Siddique, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Shimokawa H.
    • Journal Title

      Circulation

      Volume: ―

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Journal Article] Selenoprotein P promotes vascular smooth muscle cell proliferation and pulmonary hypertension -A possible novel therapeutic target-2018

    • Author(s)
      Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Md. Elias Al-Mamun, Mohammad Abdul Hai Siddique, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Shimokawa H.
    • Journal Title

      Circulation

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Journal Article] Prognostic impacts of Rho-kinase activity in circulating leucocytes in patients with vasospastic angina.2018

    • Author(s)
      Nihei T, Takahashi J, Hao K, Kikuchi Y, Odaka Y, Tsuburaya R, Nishimiya K, Matsumoto Y, Ito K, Miyata S, Sakata Y, Shimokawa H.
    • Journal Title

      European Heart Journal

      Volume: 39 Issue: 11 Pages: 952-959

    • DOI

      10.1093/eurheartj/ehx657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09413
  • [Journal Article] Selenoprotein P promotes vascular smooth muscle cell proliferation and pulmonary hypertension -A possible novel therapeutic target-2018

    • Author(s)
      Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Md. Elias Al-Mamun, Mohammad Abdul Hai Siddique, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Shimokawa H.
    • Journal Title

      Circulation

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Journal Article] Activated TAFI promotes the development of chronic thromboembolic pulmonary hypertension -A possible novel therapeutic target-2017

    • Author(s)
      Satoh T, Satoh K, Yaoita N, Kikuchi N, Omura J, Kurosawa R, Numano K, Md. Elias-Al-Mamun, Mohammad Abdul Hai Siddique, Sunamura S, Nogi M, Suzuki K, Miyata S, Morser J, Shimokawa H.
    • Journal Title

      Circ Res.

      Volume: 120 Issue: 8 Pages: 1246-1262

    • DOI

      10.1161/circresaha.117.310640

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-14F04902, KAKENHI-PROJECT-15K15046
  • [Journal Article] Shrinking basic cardiovascular research in Japan: A tip of the iceberg.2017

    • Author(s)
      Shimokawa H, Kikuchi N, Satoh K.
    • Journal Title

      Circ Res.

      Volume: 121 Issue: 4 Pages: 331-334

    • DOI

      10.1161/circresaha.117.310845

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-14F04902, KAKENHI-PROJECT-16K15198
  • [Journal Article] European Society of Cardiology (ESC) Annual Congress Report From Barcelona 20172017

    • Author(s)
      Satoh K, Takahashi J, Matsumoto Y, Tatebe S, Aoki T, Kikuchi Y, Hao K, Ohyama K, Nogi M, Suda A, Kasahara S, Sato K, Ichijo S, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 81 Issue: 12 Pages: 1758-1763

    • DOI

      10.1253/circj.CJ-17-1103

    • NAID

      130006219237

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-16K15198
  • [Journal Article] The Efficacy of a Genetic Analysis of the <i>BMPR2</i> Gene in a Patient with Severe Pulmonary Arterial Hypertension and an Atrial Septal Defect Treated with Bilateral Lung Transplantation2017

    • Author(s)
      Tatebe S, Sugimura K, Aoki T, Yamamoto S, Yaoita N, Suzuki H, Sato H, Kozu K, Konno R, Satoh K, Fukuda K, Adachi O, Saito R, Nakanishi N, Morisaki H, Oyama K, Saiki Y, Okada Y, Shimokawa H.
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 23 Pages: 3193-3197

    • DOI

      10.2169/internalmedicine.8686-16

    • NAID

      130006235510

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-16K15198
  • [Journal Article] Novel therapeutic targets of pulmonary hypertension.2016

    • Author(s)
      Yaoita N, Satoh K, Shimokawa H.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 36 Issue: 12

    • DOI

      10.1161/atvbaha.116.308263

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-14F04902, KAKENHI-PROJECT-15K15046
  • [Journal Article] RhoA/Rho-kinase in the cardiovascular system.2016

    • Author(s)
      Shimokawa H, Sunamura S, Satoh K.
    • Journal Title

      Circ Res.

      Volume: 118 Issue: 2 Pages: 352-366

    • DOI

      10.1161/circresaha.115.306532

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-14F04902, KAKENHI-PROJECT-15K15046, KAKENHI-PROJECT-15K01678, KAKENHI-PROJECT-16K15198
  • [Journal Article] Thrombin-activatable fibrinolysis inhibitor in chronic thromboembolic pulmonary hypertension.2016

    • Author(s)
      Yaoita N, Satoh K, Satoh T, Sugimura K, Tatebe S, Miyamichi-Yamamoto S, Aoki T, Miura M, Miyata S, Kawamura T, Horiuchi H, Fukumoto Y, Shimokawa H.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: in press

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Multiple Beneficial Effects of Balloon Pulmonary Angioplasty in Patients With Chronic Thromboembolic Pulmonary Hypertension2016

    • Author(s)
      Tatebe S, Sugimura K, Aoki T, Miura M, Nochioka K, Miyamichi-Yamamoto S, Yaoita N, Suzuki H, Sato H, Satoh K, Fukumoto Y, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 80 Issue: 4 Pages: 980-988

    • DOI

      10.1253/circj.CJ-15-1212

    • NAID

      130005139581

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01678, KAKENHI-PROJECT-15K09116, KAKENHI-PROJECT-15K15046, KAKENHI-PROJECT-15K19360, KAKENHI-PROJECT-15K19361, KAKENHI-PROJECT-25461037, KAKENHI-PROJECT-25461100, KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-15H04816
  • [Journal Article] Thrombin-activatable fibrinolysis inhibitor in chronic thromboembolic pulmonary hypertension.2016

    • Author(s)
      Yaoita N, Satoh K, Satoh T, Sugimura K, Tatebe S, Yamamoto S, Aoki T, Miura M, Miyata S, Kawamura T, Horiuchi H, Fukumoto Y, Shimokawa H.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 36 Issue: 6 Pages: 1293-1301

    • DOI

      10.1161/atvbaha.115.306845

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01678, KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-15H02535, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-14F04902, KAKENHI-PROJECT-15K15046, KAKENHI-PROJECT-15K09116
  • [Journal Article] Accuracy of Optical Frequency Domain Imaging for Evaluation of Coronary Adventitial Vasa Vasorum Formation After Stent Implantation in Pigs and Humans - A Validation Study.2015

    • Author(s)
      Nishimiya K, Matsumoto Y, Uzuka H, Oyama K, Tanaka A, Taruya A, Ogata T, Hirano M, Shindo T, Hanawa K, Hasebe Y, Hao K, Tsuburaya R, Takahashi J, Miyata S, Ito K, Akasaka T, Shimokawa H
    • Journal Title

      Circulation Journal

      Volume: E pub

    • NAID

      130005073155

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24790732
  • [Journal Article] The Future of Non-Invasive Angiogenic Therapy Using Acoustic Waves2015

    • Author(s)
      Ito K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 79 Issue: 9 Pages: 1906-1907

    • DOI

      10.1253/circj.CJ-15-0809

    • NAID

      130005095289

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Journal Article] Ventricular fibrillation mechanisms and cardiac restitutions: An investigation by simulation study on whole-heart model2015

    • Author(s)
      Yi Zheng,Daming Wei,Xin Zhu, Wenxi Chen, Koji Fukuda, and Hiroaki Shimokawa
    • Journal Title

      Computers in Biology and Medicine

      Volume: in press Pages: 261-268

    • DOI

      10.1016/j.compbiomed.2014.06.014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24500369, KAKENHI-PROJECT-15H04678
  • [Journal Article] PDE1C negatively regulates growth factor receptor degradation and promotes vascular smooth muscle cell proliferation.2015

    • Author(s)
      Satoh K, Kikuchi N, Kurosawa R, Shimokawa H.
    • Journal Title

      Circ Res.

      Volume: 116 Issue: 7 Pages: 1098-1100

    • DOI

      10.1161/circresaha.115.306139

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670379, KAKENHI-PROJECT-15K01678, KAKENHI-PROJECT-15K15046, KAKENHI-PROJECT-15H04816, KAKENHI-PROJECT-24390193
  • [Journal Article] Circadian Variation of Rho-Kinase Activity in Circulating Leukocytes of Patients With Vasospastic Angina2014

    • Author(s)
      Nihei T, Takahashi J, Tsuburaya R, Ito Y, Shiroto T, Hao K, Takagi Y, Matsumoto Y, Nakayama M, Miyata S, Sakata Y, Ito K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 78 Issue: 5 Pages: 1183-1190

    • DOI

      10.1253/circj.CJ-13-1458

    • NAID

      130003391088

    • ISSN
      1346-9843, 1347-4820
    • URL

      https://pure.teikyo.jp/en/publications/d81c0b38-602d-4bfe-9a04-fbe6734b44b7

    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461038
  • [Journal Article] OCT imaging for the management of pulmonary hypertension.2014

    • Author(s)
      Dai Z, Fukumoto Y, Tatebe S, Sugimura K, Miura Y, Nochioka K, Aoki T, Miyamichi-Yamamoto S, Yaoita N, Satoh K, Shimokawa H.
    • Journal Title

      JACC-Cardiovasc Imaging.

      Volume: 7 Issue: 8 Pages: 843-845

    • DOI

      10.1016/j.jcmg.2014.01.020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-24591032, KAKENHI-PROJECT-25461037, KAKENHI-PROJECT-25670379
  • [Journal Article] Different Characteristics of Postoperative Atrial Tachyarrhythmias between Congenital and Non-Congenital Heart Disease2014

    • Author(s)
      Masateru Kondo, Koji Fukuda, Yuji Wakayama, Makoto Nakano, Yuhi Hasebe, Hiroyuki Satake, Hiroaki Shimokawa
    • Journal Title

      Circulation Journal

      Volume: 78(Suppl. I)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Journal Article] Endothelial AMPK regulates blood pressure and coronary flow responses through hyperpolarization mechanism in mice.2014

    • Author(s)
      Enkhjargal B, Godo S, Sawada A, Nergui S, Saito H, Noda K, Satoh K, Shimokawa H.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 34 Issue: 7 Pages: 1505-1513

    • DOI

      10.1161/atvbaha.114.303735

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25670379
  • [Journal Article] Vascular function.2014

    • Author(s)
      Shimokawa H, Satoh K.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 34 Issue: 11 Pages: 2359-2362

    • DOI

      10.1161/atvbaha.114.304119

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25670379
  • [Journal Article] Histopathological examination by lung biopsy for the evaluation of operability and postoperative prognosis in patients with chronic thromboembolic pulmonary hypertension.2014

    • Author(s)
      Yamaki S, Ando M, Fukumoto Y, Higuchi Y, Kaneko K, Maeda K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 78 Pages: 476-482

    • NAID

      130003382220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats.2014

    • Author(s)
      Elias-Al-Mamun M, Satoh K, Tanaka SI, Shimizu T, Nergui S, Miyata S, Fukumoto Y, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 78 Pages: 967-976

    • NAID

      130003391036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Extracorporeal low-energy shock wave therapy exerts anti-inflammatory effects in acute myocardial infarction in rats in vivo.2014

    • Author(s)
      Abe Y, Ito K, Hao K, Shindo T, Ogata T, Kagaya Y, Kurosawa R, Nishimiya K, Satoh K, Miyata S, Kawakami K, Shimokawa H.
    • Journal Title

      Circ J.

      Volume: 78 Pages: 2915-2925

    • Data Source
      KAKENHI-PROJECT-25670379
  • [Journal Article] Circadian Variation of Rho-Kinase Activity in Circulating Leukocytes of Patients With Vasospastic Angina2014

    • Author(s)
      Nihei T, Takahashi J, Tsuburaya R, Ito Y, Shiroto T, Hao K, Takagi Y, Matsumoto Y, Nakayama M, Miyata S, Sakata Y, Ito K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: Mar 27(Epub ahead of print)

    • NAID

      130003391088

    • Data Source
      KAKENHI-PROJECT-23591026
  • [Journal Article] Dual roles of vascular-derived reactive oxygen species-With a special reference to hydrogen peroxide and cyclophilin A2014

    • Author(s)
      Kimio Satoh, Shigeo Godo, Hiroki Saito, Budbazar Enkhjargal, Hiroaki Shimokawa
    • Journal Title

      Journal of molecular and cellular cardiology

      Volume: (In press) Pages: 50-56

    • DOI

      10.1016/j.yjmcc.2013.12.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11F01417, KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25670379
  • [Journal Article] 2014 Williams Harvey Lecture: importance of coronary vasomotion abnormalities-from bench to bedside.2014

    • Author(s)
      Shimokawa H.
    • Journal Title

      Eur Heart J.

      Volume: 35 Issue: 45 Pages: 3180-3193

    • DOI

      10.1093/eurheartj/ehu427

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Journal Article] Visualization of Complete Regression of Pulmonary Arterial Remodeling on Optical Coherence Tomography in a Patient With Pulmonary Arterial Hypertension.2014

    • Author(s)
      Dai Z, Sugimura K, Fukumoto Y, Tatebe S, Miura Y, Nochioka K, Aoki T, Miyamichi-Yamamoto S, Yaoita N, Satoh K, Shimokawa H.
    • Journal Title

      Circ J.

      Volume: 78 Pages: 2771-2773

    • NAID

      130004700253

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Journal Article] High-sensitivity C-reactive protein: still need for next-generation biomarkers for remote future cardiovascular events.2014

    • Author(s)
      Satoh K, Shimokawa H.
    • Journal Title

      Eur Heart J.

      Volume: 35 Issue: 27 Pages: 1776-1778

    • DOI

      10.1093/eurheartj/ehu115

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25670379
  • [Journal Article] Light and dark of reactive oxygen species for vascular function.2014

    • Author(s)
      Shimokawa H, Satoh K.
    • Journal Title

      J Cardiovasc Pharmacol.

      Volume: 65

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Journal Article] Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats.2014

    • Author(s)
      Elias-Al-Mamun M, Satoh K, Tanaka S, Shimizu T, Nergui S, Miyata S, Fukumoto Y, Shimokawa H.
    • Journal Title

      Circ J.

      Volume: 78 Pages: 967-976

    • NAID

      130003391036

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Journal Article] Circadian Variation of Rho-Kinase Activity in Circulating Leukocytes of Patients With Vasospastic Angina.2014

    • Author(s)
      Nihei T, Takahashi J, Tsuburaya R, Ito Y, Shiroto T, Hao K, Takagi Y, Matsumoto Y, Nakayama M, Miyata S, Sakata Y, Ito K, Shimokawa H.
    • Journal Title

      Circ J.

      Volume: in press

    • NAID

      130003391088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Journal Article] Enhanced [18F]fluorodeoxyglucose accumulation in the right ventricular free wall predicts long-term prognosis of patients with pulmonary hypertension: a preliminary observational study.2014

    • Author(s)
      Tatebe S, Fukumoto Y, Oikawa-Wakayama M, Sugimura K, Satoh K, Miura Y, Aoki T, Nochioka K, Miura M, Yamamoto S, Tashiro M, Kagaya Y, Shimokawa H.
    • Journal Title

      Eur Heart J Cardiovasc Imaging

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Crucial role of Rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice.2014

    • Author(s)
      Ikeda S, Satoh K, Kikuchi N, Miyata S, Suzuki K, Omura J, Shimizu T, Kobayashi K, Kobayashi K, Fukumoto Y, Sakata Y, Shimokawa H.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Enhanced [18F]fluorodeoxyglucose accumulation in the right ventricular free wall predicts long-term prognosis of patients with pulmonary hypertension: a preliminary observational study.2014

    • Author(s)
      Tatebe S, Fukumoto Y, Oikawa-Wakayama M, Sugimura K, Satoh K, Miura Y, Aoki T, Nochioka K, Miura M, Yamamoto S, Tashiro M, Kagaya Y, Shimokawa H.
    • Journal Title

      Eur Heart J Cardiovasc Imaging.

      Volume: 15 Issue: 6 Pages: 666-672

    • DOI

      10.1093/ehjci/jet276

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25460608, KAKENHI-PROJECT-25461037, KAKENHI-PROJECT-25670379, KAKENHI-PROJECT-25670525
  • [Journal Article] Statins exert pleiotropic effects through SmgGD S up-regulation with a resultant Rac l degradation2013

    • Author(s)
      Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H
    • Journal Title

      Arterioscter Thromz Vasc Biol

      Volume: (in press) Issue: 7 Pages: 1591-1600

    • DOI

      10.1161/atvbaha.112.300922

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PROJECT-25461100, KAKENHI-PROJECT-25670379
  • [Journal Article] Three-dimensional-optical coherence tomography imaging of chronic thromboembolic pulmonary hypertension.2013

    • Author(s)
      Koichiro Sugimura
    • Journal Title

      European Heart Journal.

      Volume: Jul;34(28) Issue: 28 Pages: 2121-2121

    • DOI

      10.1093/eurheartj/eht203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790827, KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25461100
  • [Journal Article] Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications and prognostic impact -Multicenter registrystudy of the Japanese Coronary Spasm Association-2013

    • Author(s)
      Takagi Y, Yasuda S, Takahashi J, TsunodaR, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Goto T, Tanabe Y, Sueda S, Sato T, Ogawa S, Kubo N, Momomura S, Ogawa H, Shimokawa H
    • Journal Title

      Eur Heart J

      Volume: 34 Issue: 4 Pages: 258-267

    • DOI

      10.1093/eurheartj/ehs199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PROJECT-25670379, KAKENHI-PLANNED-20117009
  • [Journal Article] Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications and prognostic impact-Multicenter registry study of the Japanese Coronary Spasm Association-2013

    • Author(s)
      Takagi Y, Yasuda S, Takahashi J, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Goto T, Tanabe Y, Sueda S, Sato T, Ogawa S, Kubo N, Momomura S, Ogawa H, Shimokawa H
    • Journal Title

      Eur Heart J

      Volume: 34 Pages: 258-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Plasma Cyclophilin A Is a Novel Biomarker for Coronary Artery Disease2013

    • Author(s)
      Satoh K, Fukumoto Y, Sugimura K, Miura Y, Aoki T, Nochioka K, Tatebe S, Miyamichi-Yamamoto S, Shimizu T, Osaki S,Takagi Y, Tsuburaya R, Ito Y, Matsumoto Y, Nakayama M, Takeda M, Takahashi J, Ito K, Yasuda S, Shimokawa H
    • Journal Title

      Circ J

      Volume: 77 Issue: 2 Pages: 447-455

    • DOI

      10.1253/circj.CJ-12-0805

    • NAID

      10031138924

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PROJECT-23659408, KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25670379
  • [Journal Article] A double-blind, placebo-controlled clinical trial with a Rho-kinase inhibitor in pulmonary arterial hypertension; a pilot efficacy trial.2013

    • Author(s)
      Fukumoto Y, Yamada N, Matsubara H, Mizoguchi M, Uchino K, Yao A, Kihara Y, Kawano M, Watanabe H, Takeda Y, Adachi T, Osanai S, Tanabe N, Inoue T, Nakano T, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 77 Pages: 2619-2625

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Role of Endogenous Hydro gen Peroxide during Angiotensin Type 1 Receptor Blockers Administrationin Pacing-induced Metabolic Coronary Vasodilatation in Dogs in Vivo2013

    • Author(s)
      Yada T, Shimokawa H,Ogasawara Y , Kajiya F
    • Journal Title

      35th Annual InternationalIEEE EMBS Conference

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300162
  • [Journal Article] Impact of physical activity on cardiovascular events in patients with chronic heart failure2013

    • Author(s)
      Miura Y, Fukumoto Y, Miura T, Shimada K, Asakura M, Kadokami T, Ando SI, Miyata S, Sakata Y, Daida H, Matsuzaki M, Yasuda S, Kitakaze M, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 77 Pages: 2963-2972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Rho-kinase activation in patients with heart failure.2013

    • Author(s)
      Do E Z, Fukumoto Y, Sugimura K, Miura Y, Tatebe S, Yamamoto S, Aoki T, Nochioka K, Nergui S, Yaoita N, Satoh K, Kondo M, Nakano M, Wakayama Y, Fukuda K, Nihei T, Kikuchi Y, Takahashi J, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 77 Pages: 2542-2550

    • NAID

      10031191794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications and prognostic impact -Multicenter registry study of the Japanese Coronary Spasm Association-2013

    • Author(s)
      Takagi Y, Yasuda S, Takahashi J, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Goto T, Tanabe Y, Sueda S, Sato T, Ogawa S, Kubo N, Momomura S, Ogawa H, Shimokawa H.
    • Journal Title

      Eur Heart J

      Volume: 34 Pages: 258-267

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Effect of the Great East Japan Earthquake Disaster on cardiovascular diseases - A report from the 10 hospitals in the Disaster area-2013

    • Author(s)
      Aoki T, Takahashi J, Fukumoto Y, Yasuda S, Ito K, Miyata S, Shinozaki T, Inoue K, Yagi T, Komaru T, Katahira Y, Obata A, Hiramoto T, Sukegawa H, Ogata K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 77 Pages: 490-493

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Crucial Role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice.2013

    • Author(s)
      Shimizu T, Fukumoto Y, Tanaka S, Satoh K, Ikeda S, Shimokawa H.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 33 Issue: 12 Pages: 2780-2791

    • DOI

      10.1161/atvbaha.113.301357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390193, KAKENHI-PROJECT-25461100
  • [Journal Article] Optical coherence tomography is superior to intravascular ultrasound for diagnosis ofdistal-type chronic thromboembolic pulmonary hypertension.2013

    • Author(s)
      Tatebe S, Fukumoto Y, Sugimura K, Miura Y, Nochioka K, Aoki T, Miura M, Yamamoto S, Yaoita N, Satoh K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 77 Pages: 1081-1083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461100
  • [Journal Article] Plasma cyclophilin A is a novel biomarker for coronary artery disease2013

    • Author(s)
      Satoh K, Fukumoto Y, Sugimura K, Miura Y, Aoki T, Nochioka K, Tatebe S, Miyamichi-Yamamoto S, Shimizu T, Osaki S,Takagi Y, Tsuburaya R, Ito Y, Matsumoto Y, Nakayama M, Takeda M, Takahashi J, Ito K, Yasuda S, Shimokawa H
    • Journal Title

      Circ J

      Volume: 77 Pages: 447-455

    • NAID

      10031138924

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] The Great East Japan Earthquake Disaster and cardiovascular diseases2012

    • Author(s)
      Aoki T, Fukumoto Y, Yasuda S, Sakata Y, Ito K, Takahashi J, Miyata S, Tsuji I, Shimokawa H.
    • Journal Title

      Eur Heart J

      Volume: 33 Pages: 2796-2803

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice2012

    • Author(s)
      Ohashi J, Shimokawa H, et al
    • Journal Title

      Circulation Journal

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] onbehalf of the CHART-2 Investigators. Urinary albumin excretion in heart failure with preserved ejection fraction - An interim analysis of the CHART-2 Study-2012

    • Author(s)
      Miura M, Shiba N, Nochioka K, TakadaT, Takahashi J, Kohno H, Shimokawa H
    • Journal Title

      Eur J Heart Fail

      Volume: 14 Pages: 367-376

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Usefulness of the non-contact mapping system to elucidate the conduction property for the treatment of common atrial flutter2012

    • Author(s)
      Kondo M, Fukuda K, Wakayama Y, Nakano M, Hasebe Y, Shimokawa H
    • Journal Title

      PACE

      Volume: 35. Issue: 6 Pages: 1464-1471

    • DOI

      10.1111/j.1540-8159.2012.03379.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Journal Article] Long-term treatment with nifedipine suppresses coronary yperconstrcting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: Possible involvement of Rho- kinase pathway-2012

    • Author(s)
      Tsuburaya R, Yasuda S, Shiroto T, Ito Y, Gao JY, Aizawa K, Kikuchi Y, Ito K, Takahashi J, Ishibashi-Ueda H, Shimokawa H
    • Journal Title

      Eur Heart J

      Volume: 33 Pages: 791-799

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Enhanced Rho-kinase activity in patients with vasospastic angina after the Great EastJapan Earthquake.2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Takagi Y, Hao K, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 76 Pages: 2892-2894

    • NAID

      10031126063

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Involvement of Rho-kinase activation in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stents in patientswith coronary artery disease2012

    • Author(s)
      Aizawa K, Yasuda S, Takahashi J, Takii T, Kikuchi Y, Tsuburaya R, Ito Y, Nakayama M, Takeda M, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 76 Pages: 2552-2560

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Long-term treatment with nifedipine suppresses coronary hyperconstrcting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: Possible involvement of Rho-kinase pathway-2012

    • Author(s)
      Tsuburaya R, Yasuda S, Shiroto T, Ito Y, Gao JY, Aizawa K, Kikuchi Y, Ito K, Takahashi J, Ishibashi-Ueda H, Shimokawa H.
    • Journal Title

      Eur Heart J

      Volume: 33 Issue: 6 Pages: 791-799

    • DOI

      10.1093/eurheartj/ehr145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PLANNED-20117009
  • [Journal Article] Enhanced Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake.2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Takagi Y, Hao K, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 76 Pages: 2892-4

    • NAID

      10031126063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Journal Article] Mechanisms for Enhanced Endothelium-Derived Hyperpolarizing Factor-Mediated Responses in Microvessels in Mice2012

    • Author(s)
      Ohashi J, Sawada A, Nakjiima S, Noda K, Takaki A, Shimokawa H
    • Journal Title

      Circ J

      Volume: 76 Issue: 7 Pages: 1768-1779

    • DOI

      10.1253/circj.CJ-12-0197

    • NAID

      10030503846

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071
  • [Journal Article] Essential role of the bone marrow for microvascular endothelial and metabolic functions in mice2012

    • Author(s)
      Nakaj ima S, Ohashi J, Sawada A, Noda K, Fukumoto Y, Shimokawa H
    • Journal Title

      Circ Res

      Volume: 111 Issue: 1 Pages: 87-96

    • DOI

      10.1161/circresaha.112.270215

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071
  • [Journal Article] Enhanced Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Takagi Y, Hao K, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 76 Pages: 2892-4

    • NAID

      10031126063

    • Data Source
      KAKENHI-PROJECT-23591026
  • [Journal Article] Urbanization, life-style changes and incidence andin-hospital mortality from acute myocardial infarction in Japan - Report from the MIYAGI-AMI Registry-2012

    • Author(s)
      Hao K, Yasuda S, Takii T, Ito Y, Takahashi J, Ito K, Nakayama M, Shiba N, Fukumoto Y, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 76 Pages: 1136-1144

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Mechanisms for enhanced endothelium-derived hyperpolarizing factor-medited responses in microvessels in mice.2012

    • Author(s)
      Ohashi J, Sawada A, Shimokawa H, et al.
    • Journal Title

      Circulation Journal

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Journal Article] Long-term treatment with nifedipine suppresses coronary hyperconstrcting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: Possible involvement of Rho-kinase pathway-2012

    • Author(s)
      Tsuburaya R, Yasuda S, Shiroto T, Ito Y, Gao JY, Aizawa K, Kikuchi Y, Ito K, Takahashi J, Ishibashi-Ueda H, Shimokawa H.
    • Journal Title

      Eur Heart J

      Volume: 33 Pages: 791-799

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice2012

    • Author(s)
      Ohashi J, Shimokawa H, et al
    • Journal Title

      Circulation Journal

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Journal Article] EnhancedRho-kinase activity in circulating neutrophils of patients with vasospastic angina -Possible biomarker for diagnosis and disease activity assessment-2011

    • Author(s)
      Kikuchi Y, Yasuda S, Aizawa K, Tsuburaya R, Ito Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol

      Volume: 58 Pages: 1231-1237

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Eocosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potentials.2011

    • Author(s)
      Tsuburaya R, Yasuda S, Shimokawa H, et al.
    • Journal Title

      European Heart Journal.

      Volume: 51 Pages: 329-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Journal Article] Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina.2011

    • Author(s)
      Kikuchi Y, Yasuda S, Aiazawa K, Tsuburaya R, Ito Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H.
    • Journal Title

      -possible biomarker for diagnosis and disease activity assessment-J Am Coll Cardiol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] 狭心症に対する低出力体外衝撃波を用いた血管新生療法2011

    • Author(s)
      伊藤健太, 下川宏明
    • Journal Title

      日本医事新報

      Volume: 4549 Pages: 48-49

    • Data Source
      KAKENHI-PROJECT-21590922
  • [Journal Article] Long-Term Treatment with Eicosapentaenoic Acid Ameliorates Myocardial Ischemia-Reperfusion Injury in Pigs in Vivo-Involvement of Rho-kinase Pathway Inhibition-.2011

    • Author(s)
      Gao JY, Yasuda S, Tsuburaya R, Ito Y, Shiroto T, Hao K, Aizawa K, Kikuchi Y, Ito K, Shimokawa H.
    • Journal Title

      Circ J. in press

    • NAID

      10029127641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Rho-kinase : Important new therapeutic target in cardiovascular disease2011

    • Author(s)
      Satoh K, Fukumoto Y, Shimokawa H
    • Journal Title

      American Journal of Physiology

      Volume: 301 Pages: 287-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Rho-kinase:Important new therapeutic target in cardiovascular diseases2011

    • Author(s)
      Satoh K, Fukumoto Y, Shimokawa H
    • Journal Title

      Am J Physiol

      Volume: 301 Issue: 2 Pages: 287-296

    • DOI

      10.1152/ajpheart.00327.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PROJECT-23659408
  • [Journal Article] Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina : a possible biomarker for diagnosis and disease activity assessment2011

    • Author(s)
      Kikuchi Y, Yasuda S, Aizawa K, Tsuburaya R, Ito Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol

      Volume: 58 Pages: 1231-7

    • Data Source
      KAKENHI-PROJECT-23591026
  • [Journal Article] Prognostic impact of myocardial interstitial fibrosis in non-ischemic heart failure2011

    • Author(s)
      Aoki T, Fukumoto Y, Sugimura K, Oikawa M, Satoh K, Nakano M, Nakayama M, Shimokawa H
    • Journal Title

      Circ J

      Volume: 75 Pages: 2605-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Eicosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potential in pigs.2011

    • Author(s)
      Tsuburaya R, Yasuda S, Ito Y, Shiroto T, Gao YJ, Ito K, Shimokawa H.
    • Journal Title

      J Moll Cell Cardiol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Long-term treatment with nifedipine suppresses coronary hypercon- stricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo -Possible involve- ment of Rho-kinase pathway-2011

    • Author(s)
      Tsuburaya R, Yasuda S, Shimokawa H., et al.
    • Journal Title

      Eur Heart J. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] 低出力体外衝撃波治療2011

    • Author(s)
      伊藤健太, 下川宏明
    • Journal Title

      臨床と研究

      Volume: 88 Pages: 69-73

    • NAID

      130004698649

    • Data Source
      KAKENHI-PROJECT-21590922
  • [Journal Article] Rho-kinase : Important new therapeutic target in cardiovascular diseases2011

    • Author(s)
      Satoh K, Fukumoto Y, Shimokawa H
    • Journal Title

      American Journal of Physiology

      Volume: 301 Pages: 287-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Journal Article] Extracorporeal shock wave therapy for ischemic cardiovascular disorders2011

    • Author(s)
      Ito K, Fukumoto Y, Shimokawa H.
    • Journal Title

      Am J Cardiovasc Drugs

      Volume: 11 Pages: 295-302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Journal Article] Long-term treatment with nifedipine suppresses coronary hyperconstrcting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo-Possible involvement of Rho-kinase pathway-2011

    • Author(s)
      Tsuburaya R, Yasuda S,…, Shimokawa H.
    • Journal Title

      European Heart Journal

      Volume: (未定 In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina: a possible biomarker for diagnosis and disease activity assessment.2011

    • Author(s)
      Kikuchi Y, Yasuda S, Aizawa K, Tsuburaya R, Ito Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol.

      Volume: 58 Pages: 1231-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Journal Article] Vascular-derived reactive oxygen species for homeostasis and diseases2011

    • Author(s)
      Satoh K, Shimokawa H
    • Journal Title

      Nitric Oxide

      Volume: 25 Issue: 2 Pages: 211-215

    • DOI

      10.1016/j.niox.2011.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PROJECT-23659408
  • [Journal Article] Treatment with nifedipine suppresses coronary hyperconstricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo-Possible involvement of Rho-kinase pathway-2011

    • Author(s)
      Tsuburaya R, Yasuda S, Shiroto T, Ito Y, Gao JY, Aizawa K, Kikuchi Y, Ito K, Takahashi J, Ishibashi-Ueda H, Shimokawa H.
    • Journal Title

      Eur Heart J. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Intensive Intensive immunosuppressive therapy improves pulmonary hemodynamics and long-term prognosis in patients with pulmonary arterial hypertension associated with connective tissue disease2011

    • Author(s)
      Miyamichi-Yamamoto S, Fukumoto Y, Sugimura K, Ishii T, Satoh K, Miura Y, Tatebe S, Nochioka K, Aoki T, Do E Z, Shimokawa H
    • Journal Title

      Circ J

      Volume: 75 Pages: 2668-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Long-term treatment with nifedipine suppresses coronary hyperconstrcting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo-Possible involvement of Rho-kinase pathway-2011

    • Author(s)
      Tsuburaya R, Yasuda S, Shimokawa H.
    • Journal Title

      European Heart Journal

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Journal Article] Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.2011

    • Author(s)
      Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T.
    • Journal Title

      Cell Metabolism 13

      Pages: 294-307

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] 体外衝撃波を用いた非侵襲性血管新生治療2010

    • Author(s)
      伊藤健太、下川宏明
    • Journal Title

      日本内科学会雑誌

      Volume: 99 Pages: 188-194

    • NAID

      10027509204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Journal Article] Complete disruption of all nitric oxide synthase genes causes markedly accelerated renal lesion formation following unilateral ureteral obstruction in mice in vivo.2010

    • Author(s)
      Morisada N, Nomura M, Nishii H, Furuno Y, Sakanashi M, Sabanai K, Toyohira Y, Ueno S, Watanabe S, Tamura M, Matsumoto T, Tanimoto A, Sasaguri Y, Shimokawa H, Kusuhara K, Yanagihara N, Shirahata A, Tsutsui M.
    • Journal Title

      J Pharmacol Sci. 114

      Pages: 379-389

    • NAID

      10029890896

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Optical coherence tomography as a novel diagnostic tool for distal type chronic thromboembolic pulmonary hypertension2010

    • Author(s)
      Tatebe S, Fukumoto Y, Sugimura K, Nakano M, Miyamichi S, Satoh K, Oikawa M, Shimokawa H
    • Journal Title

      Circ J

      Volume: 74 Pages: 1742-4

    • NAID

      10026566233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Erythropoietin enhances hydrogen peroxide-mediated dilatation of canine coronary collateral arterioles during myocardial ischemia in dogs in vivo.2010

    • Author(s)
      Yada T, Shimokawa H, Hiramatsu O, et al.
    • Journal Title

      American Journal of Physiology

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Journal Article] Pathophysiological relevance of NO signaling in cardiovascular system : novel insight form mice lacking all NO synthases.2010

    • Author(s)
      Tsutsui M, Shimokawa H, Otsuji Y, Yanagihara N.
    • Journal Title

      Pharmacology & Therapeutics 128(Review)

      Pages: 499-508

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Authors' reply.2010

    • Author(s)
      Yasuda S, Shiroto T, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol. 55

      Pages: 1399-1400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Reply2010

    • Author(s)
      Yasuda S, Shiroto T, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] 体外衝撃波を用いた非侵襲性血管新生治療2010

    • Author(s)
      伊藤健太, 下川宏明
    • Journal Title

      日内学雑誌

      Volume: 99 Pages: 188-194

    • NAID

      10027509204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Journal Article] Combination therapy with olmesartan and azelnidipine improves EDHF-mediated responses in diabetic Apolipoprotein E-deficient mice.2010

    • Author(s)
      Hosoya M, Ohashi J, Shimokawa H.
    • Journal Title

      Circ J. 74

      Pages: 798-806

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Erythropoietin enhances hydrogen peroxide-mediated dilatation of canine coronary collateral arterioles during myocardial ischemia in dogs in vivo.2010

    • Author(s)
      Yada T, Shimokawa H, Hiramatsu O, et al.
    • Journal Title

      American Journal of Physiology

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Prognostic effects of calcium channel blockers in patients with vasospastic angina2010

    • Author(s)
      Nishigaki K, Inoue Y, Yamanouchi Y, Fukumoto Y, Yasuda S, Sueda S, Urata H, Shimokawa H, Minatoguchi S
    • Journal Title

      Circ J

      Volume: 74 Pages: 1943-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Erythropoietin Enhances Hydrogen Peroxide-mediated Dilatation of Canine Coronary Collateral Arterioles during Myocardial Ischemia in Dogs in Vivo.2010

    • Author(s)
      Yada T, Shimokawa H, Ogasawara Y , Kajiya F
    • Journal Title

      American Journal of Physiology-Heart and Circulatory Physiology

      Volume: 299巻 Issue: 6 Pages: H1928-H1935

    • DOI

      10.1152/ajpheart.00331.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300162
  • [Journal Article] Authors' reply.2010

    • Author(s)
      Yasuda S, Shiroto T, Shimokawa H
    • Journal Title

      J Am Coll Cardiol.

      Volume: 55 Pages: 1399-1400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Hydrogen peroxide as an endothelium-delived hyperpolarizing factor2010

    • Author(s)
      Shimokawa H
    • Journal Title

      Pflugers Arch (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-20117001
  • [Journal Article] Cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs in vivo2010

    • Author(s)
      Ito Y, Ito K, Shiroto T, Tsuburaya R, Yi GJ, Takeda M, Fukumoto Y, Yasuda S, Shimokawa H
    • Journal Title

      Coron Artery Dis

      Volume: 21 Pages: 304-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Severe dyslipidemia, atherosclerosis, and sudden cardiac death in mice lacking all NO synthases fed a high-fat diet.2010

    • Author(s)
      Yatera Y, Shibata K, Furuno Y, Sabanai K, Morisada N, Nakata S, Morishita T, Toyohira Y, Wang KY, Tanimoto A, Sasaguri Y, Tasaki H, Nakashima Y, Shimokawa H, Yanagihara N, Otsuji Y, Tsutsui M.
    • Journal Title

      Cardiovasc Res. 87

      Pages: 675-682

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Erythropoietin enhances hydrogen peroxide- mediated dilatation of canine coronary collateral arterioles during myocardial ischemia in dogs in invio.2010

    • Author(s)
      Yada T, Shimokawa H, Hiramatsu O, et al.
    • Journal Title

      Am J Physiol. 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Hydrogen peroxide as an endothelium-derived hyperpolarizing factor.2010

    • Author(s)
      Shimokawa H.
    • Journal Title

      European Journal of Physiology

      Volume: 459 Pages: 915-922

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Trends in acute myocardial infarction and mortality over 30 years in Japan: Report from the MIYAGI-AMI Registry Study2010

    • Author(s)
      Takii T, Yasuda S, Takahashi J, Ito K, Shiba N, Shirato K, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 74 Pages: 93-100

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris2010

    • Author(s)
      Kikuchi Y, Ito K, Ito Y, Shiroto T, Tsuburaya R, Aizawa K, Hao K, Fukumoto Y, Takahashi J, Takeda M, Nakayama M, YasudaS, Kuriyama S, Tsuji I, Shimokawa H.
    • Journal Title

      Circ J

      Volume: 74 Pages: 589-591

    • NAID

      10025943921

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension2010

    • Author(s)
      Fujita H, Fukumoto Y, Saji K, Sugimura K, Demachi J, Nawata J, Shimokawa H
    • Journal Title

      Heart Vessels

      Volume: 25 Pages: 144-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Double-blind and placebo-controlled study of the effectiveness and safety of extra corporeal cardiac shock wave therapy for severe angina pectoris.2010

    • Author(s)
      Kikuchi Y, Shimokawa H, et al.
    • Journal Title

      Circulation Journal 74

      Pages: 589-591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Nitric oxide synthases in the pathogenesis of cardiovascular disease -Lessons form genetically modified mice-2010

    • Author(s)
      Shimokawa H
    • Journal Title

      Pflugers Arch -Eur J Physiol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Hypertension promotes phosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 in rats-Implication for the pathogenesis of hypertensive vascular disease-2010

    • Author(s)
      Sugimura K, Fukumoto Y, Nawata J, Wang H, Onoue N, Tada T, Shirato K, Shimokawa H
    • Journal Title

      Tohoku J Exp Med

      Volume: 222 Pages: 201-210

    • NAID

      10027459508

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Prevalence and clinical implication of metabolic syndrome in chronic heart failure2010

    • Author(s)
      Miura Y, Fukumoto Y, Shiba N, Miura T, Shimada K, Iwama Y, Takagi A, Matsusaka H, Tsutsumi T, Yamada A, Kinugawa S, Asakura M, Okamatsu S, Tsutsui H, Daida H, Matsuzaki M, Tomoike H, Shimokawa H
    • Journal Title

      Circ J

      Volume: 74 Pages: 2612-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] OX40 ligand plays an important role in the development of atherosclerosis through vasa vasorum neovascularization2010

    • Author(s)
      Nakano M, Fukumoto Y, Satoh K, Ito Y, Kagaya Y, Ishii N, Sugamura K, Shimokawa H
    • Journal Title

      Cardiovasc Res

      Volume: 88 Pages: 539-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Spontaneous development of left ventricular hypertrophy and diastolic dysfunction in mice lacking all nitric oxide synthases.2010

    • Author(s)
      Shibata K, Yatera Y, Furuno Y, Sabanai K, Morisada N, Nakata S, Morishita T, Yamazaki F, Tanimoto A, Sasaguri Y, Tasaki H, Nakashima Y, Shimokawa H, Yanagihara N, Otsuji Y, Tsutsui M.
    • Journal Title

      Circ J. 74

      Pages: 2681-2692

    • NAID

      10027424618

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Double-blind and placebo-controlled study of the effectiveness and safety of extra corporeal cardiac shock wave therapy for severe angina pectoris2010

    • Author(s)
      Kikuchi Y, Shimokawa H, et al.
    • Journal Title

      Circulation Journal 74

      Pages: 589-591

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Nitric oxide synthases in the pathogenesis of cardiovascular disease.2010

    • Author(s)
      Shimokawa H, Tsutsui M.
    • Journal Title

      European Journal of Physiology

      Volume: 459 Pages: 959-967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Journal Article] Nitric oxide synthases in the pathogenesis of cardiovascular disease-Lessons form genetically modified mice-2010

    • Author(s)
      Shimokawa H, Tsutsui M.
    • Journal Title

      Pflugers Arch 459(Review)

      Pages: 959-967

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Nitric oxide synthases in the pathogenesis of cardiovascular disease-Lessons form genetically modified mice-2010

    • Author(s)
      Shimokawa H, et al
    • Journal Title

      Pflusers Arch

      Volume: 459 Pages: 959-967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris2010

    • Author(s)
      Kikuchi Y, Ito K, Ito Y, Shiroto T, Tsuburaya R, Aizawa K, Hao K, Fukumoto Y, Takahashi J, Takeda M, Nakayama M, Yasuda S, Kuriyama S, Tsuji I, Shimokawa H
    • Journal Title

      Circ J

      Volume: 74 Pages: 589-91

    • NAID

      10025943921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Identification of new prognostic factors of pulmonary hypertension2010

    • Author(s)
      Miura Y, Fukumoto Y, Sugimura K, Oikawa M, Nakano M, Tatebe S, Miyamichi S, Satoh K, Shimokawa H
    • Journal Title

      Circ J

      Volume: 74 Pages: 1965-71

    • NAID

      10026971784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation2009

    • Author(s)
      Toyohara T, Suzuki T, Morimoto R, Akiyama Y, Souma T, Shiwaku HO, Takeuchi Y, Mishima E, Abe M, Tanemoto M, Masuda S, Kawano H, Maemura K, Nakayama M, Sato H, Mikkaichi T, Yamaguchi H, Fukui S, Fukumoto Y, Shimokawa H, Inui K, Terasaki T, Goto J, Ito S, Hishinuma T, Rubera I, Tauc M, Fujii-Kuriyama Y, Yabuuchi H, Moriyama Y, Soga T, Abe T
    • Journal Title

      J Am Soc Nephrol

      Volume: 20 Pages: 2546-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.2009

    • Author(s)
      Rashid M, Tawara S, Shimokawa H.
    • Journal Title

      Circ J. 73

      Pages: 361-370

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Statin ameliorates hypoxia-induced pulmonary hypertension associated with down-regulated stromal cell-derived factor-12009

    • Author(s)
      Satoh K, Fukumoto Y, Nakano M, Sugimura K, Nawata J, Demachi J, Karibe A, Kagaya Y, Ishii N, Sugamura K, Shimokawa H
    • Journal Title

      Cardiovasc Res

      Volume: 81 Pages: 226-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Role of Rho-kinase in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stent in pies in vivo2009

    • Author(s)
      Shiroto T, Shimokawa H, et al.
    • Journal Title

      Journal of American College Cardiology 54

      Pages: 2321-2329

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Role of Rho-kinase in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stent in pigs in vivo.2009

    • Author(s)
      Shiroto T, Yasuda S, Tsuburaya R, Ito Y, Takahashi J, Ito K, Ishibashi-Ueda H, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol. 54

      Pages: 2321-2329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Statin Ameliorates Hypoxia-Induced Pulmonary Hypertension Associated with Down-regulated Stromal Cell-Derived Factor-12009

    • Author(s)
      Satoh K, Shimokawa H, et.al.
    • Journal Title

      Cardiovascular Research 81

      Pages: 226-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Diabetes Mellitus Accelerates Left Ventricular Diastolic Dysfunction through Activation of Renin-Angiotensin System in Hypertensive2009

    • Author(s)
      Fukui S, Fukumoto Y, Suzuki J, Saji K, Nawata J, Shinozaki T, Kagaya Y, Watanabe J, Shimokawa H
    • Journal Title

      Hypertension Research (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Journal Article] Diabetes mellitus accelerates left ventricular diastolic dysfunction through activation of the renin-angiotensin system in hypertensive rats2009

    • Author(s)
      Fukui S, Fukumoto Y, Suzuki J, Saji K, Nawata J, Shinozaki T, Kagaya Y, Watanabe J, Shimokawa H
    • Journal Title

      Hypertens Res

      Volume: 32 Pages: 472-80

    • NAID

      10024831111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors2009

    • Author(s)
      Rashid M, Tawara S, Fukumoto Y, Seto M, Yano K, Shimokawa H
    • Journal Title

      Circ J

      Volume: 73 Pages: 361-70

    • NAID

      110007042186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Endothelial dysfunction and vascular disease.2009

    • Author(s)
      Vanhoutte PM, Shimokawa H, et al.
    • Journal Title

      Acta Physiologica

      Pages: 193-222

    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Evidence for Rho-Kinase Activation in Patients With Pulmonary Arterial Hypertension2009

    • Author(s)
      Do E Z, Fukumoto Y, Takaki A, Tawara S, Ohashi J, Nakano M, Tada T, Saji K, Sugimura K, Fujita H, Hoshikawa Y, Nawata J, Kondo T, Shimokawa H
    • Journal Title

      Circ J

      Volume: 73 Pages: 1731-9

    • NAID

      10025935263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Journal Article] Nitric oxide synthases and cardiovascular diseases-Insights form genetically modified mice-2009

    • Author(s)
      Tsutsui M, Shimokawa H, Otsuji Y, Ueta Y, Sasaguri Y, Yanagihara N.
    • Journal Title

      Circ J 73(Review)

      Pages: 986-993

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Role of Rho-kinase in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stent in pigs in vivo.2009

    • Author(s)
      Shiroto T, Shimokawa H, et al.
    • Journal Title

      Journal of American College Cardiology 54

      Pages: 2321-2329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Evidence for Rho-Kinase Activation in Patients With Pulmonary Arterial Hypertension2009

    • Author(s)
      Zhulanqiqige Do., Shimokawa H, et al.
    • Journal Title

      Circulation Journal 73

      Pages: 1731-1739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Role of Rho-kinase in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stents in pigs in vivo.2009

    • Author(s)
      Shiroto T, Yasuda S, Tsuburaya R, Ito Y, Takahashi J, Ito K, Ishibashi-Ueda H, Shimokawa H.
    • Journal Title

      J Am Coll Cardiol. 54(24)

      Pages: 2321-2329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Journal Article] Evidence for Rho-Kinase Activation in Patients With Pulmonary Arterial Hypertension2009

    • Author(s)
      Zhulanqiqige Do., Shimokawa H, et al.
    • Journal Title

      Circulation Journal 73

      Pages: 1731-1739

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Enhanced pulsatile pressure accelerates vascular smooth muscle migration. -Implications for atherogenesis of hypertension-2008

    • Author(s)
      Tada T, Shimokawa H, et.al.
    • Journal Title

      Cardiovascular Research 80

      Pages: 346-353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice2008

    • Author(s)
      Takaki A, Shimokawa H, et.al.
    • Journal Title

      J Exp Med 205

      Pages: 2053-2063

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-20117001
  • [Journal Article] Spatial Non-uniformity of Excitation-Contraction Coupling Can Enhanc e Arrhythmogenic Delayed Afterdepolarizations in Rat Cardiac Muscle2008

    • Author(s)
      Miura M, Shimokawa H, et.al.
    • Journal Title

      Cardiovascular Research 80

      Pages: 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase.2008

    • Author(s)
      Ulrich M, Petre A, Youhnovski N, Promm F, Schirle M, Schumm M, Pero R, Doyle A, Checkel J, Kita H, Thiyagarajan N, Ravi Acharya K, Schmid-Grendelmeier P, Simon HU, Schwarz H, Tsutsui M, Shimokawa H, Bellon G, Lee JJ, Przybylski M, Doering G.
    • Journal Title

      J Biol Chem. 283(42)

      Pages: 28629-28640

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Extracorporeal shock wave therapy ameliorates hindlimb ischemia in rabbits2008

    • Author(s)
      Oi K, Fukumoto Y, Ito K, Uwatoku T, Abe K, Hizume T, Shimokawa H
    • Journal Title

      Tohoku J Exp Med 214

      Pages: 151-158

    • NAID

      10024166862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] Genetic disruption of all nitric oxide synthase isoforms enhances bone mineral density and bone turnover in mice in vivo : Involvement of the renin-angiotensin system.2008

    • Author(s)
      Sabanai K, Tsutsui M, Sakai A, Hirasawa H, Tanaka S, Nakamura E, Tanimoto A, Sasaguri Y, Ito M, Shimokawa H, Nakamura T, Yanagihara N.
    • Journal Title

      J Bone Miner Res. 23(5)

      Pages: 633-643

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Crucial role of endothelial nitric oxide syntahses systen in endothelium- dependent hyperpolarization in mice.2008

    • Author(s)
      Takaki A, Morikawa K, Shimokawa H.
    • Journal Title

      J Exp Med. 205

      Pages: 2053-2063

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Long-term Inhibition of Rho-kinase Ameliorates Diastolic Heart Failure in Hypertensive Rats2008

    • Author(s)
      Fukui S, Fukumoto Y, Suzuki J, Saji K, Nawata J, Tawara S, Shinozaki T, Kagaya Y, Shimokawa H
    • Journal Title

      J Cardiovasc Pharmacol 51(3)

      Pages: 317-326

    • NAID

      10024857674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Journal Article] Extracorporeal cardiac shock wave therapy for ischemic heart disease2008

    • Author(s)
      Shimokawa H, Ito K, Fukumoto Y, Yasuda S
    • Journal Title

      Shock Waves 8

      Pages: 449-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] Extracorporeal cardiac shock wave therapy for ischemic heart disease2008

    • Author(s)
      Shimokawa H, Ito K, et.al.
    • Journal Title

      Shock Waves 17

      Pages: 449-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] 低出力体外衝撃波を用いた血管新生療法2008

    • Author(s)
      伊藤健太、下川宏明
    • Journal Title

      Vascular Medicine 4

      Pages: 189-191

    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice2008

    • Author(s)
      Takaki A, Morikawa K, Murayama Y, Yamagishi H, Hosoya M, Ohashi J, Shimokawa H
    • Journal Title

      Journal of cardiovascular pharmacology 52(6)

      Pages: 510-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] 現代医学の焦点 : 衝撃波による狭心症治療2008

    • Author(s)
      伊藤健太、下川宏明
    • Journal Title

      日本臨床 66

      Pages: 2019-2026

    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] Spontaneous myocardial infarction in mice lacking all nitric oxide synthase isoforms.2008

    • Author(s)
      Nakata S, Tsutsui M, Shimokawa H, Suda O, Morishita T, Shibata K, Yatera Y, Sabanai K, Tanimoto A, Nagasaki M, Tasaki H, Sasaguri Y, Nakashima Y, Otsuji Y, Yanagihara N.
    • Journal Title

      Circulation. 117

      Pages: 2211-2223

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] Extracorporeal cardiac shock wave therapy for ischemic heart disease.2008

    • Author(s)
      Shimokawa H, Ito K, et. al.
    • Journal Title

      Shock Waves (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] Spontaneous myocardial infarction and nitric oxide synthase.2008

    • Author(s)
      Tsutsui M, Nakata S, Shimokawa H, Otsuji Y, Yanagihara N.
    • Journal Title

      Trends Cardiovasc Med 18(Review)

      Pages: 275-279

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] 綜説シリーズ現代医学の焦点 : 衝撃波による狭心症治療2008

    • Author(s)
      伊藤健太、下川宏明
    • Journal Title

      日本臨床 66

      Pages: 2019-2026

    • Data Source
      KAKENHI-PROJECT-19590801
  • [Journal Article] Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in rats2008

    • Author(s)
      Fukui S, Shimokawa H, et.al.
    • Journal Title

      J Cardiovasc Pharmacol 51

      Pages: 317-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice.2008

    • Author(s)
      Takaki A, Morikawa K, Tsutsui M, Murayama Y, Tekes E, Yamagishi H, Yanagihara N, Shimokawa H.
    • Journal Title

      J Exp Med. 205

      Pages: 2053-2063

    • Data Source
      KAKENHI-PROJECT-20390074
  • [Journal Article] ncreased static pressure promotes migration of vascular smooth muscle cells -Involvement of Rho-kinase pathway-2008

    • Author(s)
      Onoue N, Shimokawa H, et.al.
    • Journal Title

      J Cardiovasc Pharmacol 51

      Pages: 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Journal Article] Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice2008

    • Author(s)
      Takaki A, Morikawa K, Tsutsui M, Murayama Y, Tekes E, Yamagishi H, Ohashi J, Yada T, Yanagihara N, Shimokawa H
    • Journal Title

      The Journal of experimental medicine 205(9)

      Pages: 2053-2063

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Bone-marrow-derived matrix metalloproteinase-14 : a novel target for plague stability2008

    • Author(s)
      Shimokawa H
    • Journal Title

      Circulation 117(9)

      Pages: 863-865

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Journal Article] Development of Rho-kinase inhibitors for cardiovascular medicine.2007

    • Author(s)
      Shimokawa H, et. al.
    • Journal Title

      Trends Pharmacol Sci. 28

      Pages: 296-302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659218
  • [Journal Article] Important role of hydrogen peroxide in pacing-induced metabolic coronary vasodilatation in dogs in vivo.2007

    • Author(s)
      Yada T, Shimokawa H, Hiramatsu O, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F.
    • Journal Title

      J Am Coll Cardiol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Important role of hydrogen peroxide in pacing-induced metabolic coronary vasodilatation in dogs in vivo.2007

    • Author(s)
      Yada T, Shimokawa H, et al.
    • Journal Title

      Journal of the American College of Cardiolgy (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] 内皮由来過分極因子と内皮機能障害2006

    • Author(s)
      高木文, 下川宏明
    • Journal Title

      日本臨床 64

      Pages: 240-243

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Cardioprotective role of hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo.2006

    • Author(s)
      Yada T, Shimokawa H, et al.
    • Journal Title

      American Journal of Physiology 291

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] NO/活性酸素による血管シグナル伝達機構2006

    • Author(s)
      森川敬子, 下川宏明
    • Journal Title

      細胞工学 25

      Pages: 166-169

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Cardioprotective role of hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo.2006

    • Author(s)
      Yada T, Shimokawa H, Hiramatsu O, Shinozaki Y, Mori H, Kiyooka T, Goto M, Ogasawara Y, Kajiya F.
    • Journal Title

      Am J Physiol. 291

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in animals and humans. (Review)2005

    • Author(s)
      Shimokawa H, Morikawa K.
    • Journal Title

      Journal of Molecular and Cellular Cardiology. 39

      Pages: 725-732

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Rho-kinase is an important therapeutic target in cardiovascular medicine.2005

    • Author(s)
      Shimokawa H, Takeshita A.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 25

      Pages: 1767-1775

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin converting enzyme inhibitor on EDHF-mediated responses in mice.2005

    • Author(s)
      Fujiki T, Shimokawa H, et al.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology 25

      Pages: 766-771

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Beneficial effects of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia-reperfusion injury in canine coronary microcirculation in vivo.2005

    • Author(s)
      Yada T, Shimokawa H, et al.
    • Journal Title

      Journal of American College of Cardiology 45

      Pages: 599-607

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin converting enzyme inhibitor on EDHF-mediated responses in mice.2005

    • Author(s)
      Fujiki T, Shimokawa H, et al.
    • Journal Title

      Arteriosclrosis, Thrombosis, and Vascular Biology (in press)

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Beneficial effects of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia-reperfusion injury in canine coronary microcirculation in vivo.2005

    • Author(s)
      Yada T, Shimokawa H, et al.
    • Journal Title

      J Am Coll Cardiol. 45

      Pages: 599-607

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Rho-kinase is an important therapeutic target in cardiovascular medicine.2005

    • Author(s)
      Shimokawa H, Takeshita A.
    • Journal Title

      Arterioscler Thromb vase Biol. 25

      Pages: 1767-1775

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in animals and humans. (Review)2005

    • Author(s)
      Shimokawa H, Morikawa K
    • Journal Title

      Journal of Molecular and Cellular Cardiology 39

      Pages: 725-732

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Influence of diabetes, hypercholesterolemia, and their combination on EDHF-mediated responses in mice.2005

    • Author(s)
      Morikawa K, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology (in press)

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin converting enzyme inhibitor on EDHF-mediated responses in mice.2005

    • Author(s)
      Fujiki T, Shimokawa H, et al.
    • Journal Title

      Arteriosclrosis, Thrombosis, and Vascular Biology 25

      Pages: 766-771

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Rho-kinase is an important therapeutic target in cardiovascular medicine. (Review)2005

    • Author(s)
      Shimokawa H, Takeshita A.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology 25

      Pages: 1767-1775

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms.2005

    • Author(s)
      Morishita T, Tsutsui M, Shimokawa H, et al.
    • Journal Title

      Proceedings of National Academy Science USA 102

      Pages: 10616-10621

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in animals and humans.2005

    • Author(s)
      Shimokawa H, Morikawa K.
    • Journal Title

      J Mol Cell Cardiol.(Review) 3 9

      Pages: 725-732

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Prostacyclin does not inhibit Rho-kinase : An implication for the treatment of pulmonary hypertension.2005

    • Author(s)
      Abe K, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology 45

      Pages: 120-124

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms.2005

    • Author(s)
      Morishita T, Tsutsui M, Shimokawa H, Sabanai K, Tasaki H, Suda 0, Nakata S, Tanimoto A, Wang K-Y, Ueta Y, Sasaguri Y, Nakashima Y, Yanagihara N.
    • Journal Title

      Proc Nat'l Acad Sci USA. 102

      Pages: 10616-10621

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms.2005

    • Author(s)
      Morishita T, Tsutsui M, Shimokawa H. et al.
    • Journal Title

      Proceedings of the National Academy of Sciences, USA 102

      Pages: 10616-10621

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin converting enzyme inhibitor on EDHF-mediated responses in mice.2005

    • Author(s)
      Fujiki T, Shimokawa H, Morikawa K, Kubota H, Hatanakla M, Talukder MAH, Matoba T, Takleshita A, Sunagawa K.
    • Journal Title

      Arterioscler Thromb Vase Biol. 25

      Pages: 766-771

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension.2005

    • Author(s)
      Fukumoto Y, Shimokawa H, et al.
    • Journal Title

      Heart 91

      Pages: 391-392

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Rho-kinase inhibitor improves increased vascular resistance and impaired vasodilation of the forearm in patients with heart failure.2005

    • Author(s)
      Kishi T, Hirooka Y, Shimokawa H, et al.
    • Journal Title

      Circulation 111

      Pages: 2741-2747

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Influence of diabetes, hypercholesterolemia, and their combination on EDHF-mediated responses in mice.2005

    • Author(s)
      Morikawa K, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology 45

      Pages: 485-490

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice.2004

    • Author(s)
      Hattori T, Shimokawa H, et al.
    • Journal Title

      Circulation 109

      Pages: 2234-2239

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Usefulness of fasudil, a Rho-kinase inhibitor, to treat intractable severe coronary spasm after coronary artery bypass surgery.2004

    • Author(s)
      Inokuchi K, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 437-445

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats.2004

    • Author(s)
      Abe K, Shimokawa H, et al.
    • Journal Title

      Circulation Research 94

      Pages: 385-393

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.2004

    • Author(s)
      Oi K, Shimokawa H, et al.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 24

      Pages: 918-922

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Important role of superoxide dismutase in EDHF-mediated responses of human mesenteric arteries.2004

    • Author(s)
      Morikawa K, Shimokawa H.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 552-556

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Important role of superoxide dismutase in EDHF-mediated responses of human mesenteric arteries.2004

    • Author(s)
      Morikawa K, Matoba T, Kubota H, Hatanaka M, Fujiki T, Takahashi S, Shimokawa H.
    • Journal Title

      J Cardiovasc Pharmacol. 44

      Pages: 552-556

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries -Involvement of multiple mechanism2004

    • Author(s)
      Matsumoto Y, Shimokawa H, et al.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology 24

      Pages: 181-186

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Important role of superoxide dismutase in EDHF-mediated responses of human mesenteric arteries2004

    • Author(s)
      Morikawa K, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 552-556

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Divergent effects of estrogen and nicotine on Rho-kinase expression in human coronary vascular smooth muscle cells.2004

    • Author(s)
      Hiroki J, Shimokawa H, et al.
    • Journal Title

      Biophys Biochem Res Commun. 326

      Pages: 154-159

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.2004

    • Author(s)
      Oi K, Shimokawa H, et al.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology 24

      Pages: 918-922

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Endothelial nitric oxide synthase-independent effect of an ACE inhibitor on coronary flow response to bradykinin in mice.2004

    • Author(s)
      Talukder MAH, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 557-563

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice.2004

    • Author(s)
      Hattori T, Shimokawa H, et al.
    • Journal Title

      Circulation Research 94

      Pages: 46-52

    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Upregulated neuronal nitric oxide synthase compensates coronary flow response to bradykinin in endothelial nitric oxide-deficient mice.2004

    • Author(s)
      Talukder MAH, Shimokawa H, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 437-445

    • Data Source
      KAKENHI-PROJECT-16209027
  • [Journal Article] Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.2004

    • Author(s)
      Oi K, Shimokawa H, et al.
    • Journal Title

      Arterioscler Thromb Yasc Biol. 24

      Pages: 918-922

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Rho-kinase inhibition with intracoronary fasudil prevents myocardial ischemia in patients with angina and normal coronary angiograms.2003

    • Author(s)
      Mohri M, Shimokawa H, et al.
    • Journal Title

      J Am Coll Cardiol. 41

      Pages: 15-19

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] Gender differences in clinical characteristics and outcomes of patients with vasospastic angina -A report from the Japanese Coronary SpasmAssociation-

    • Author(s)
      Kawana A, Takahashi J, Takagi Y, Yasuda S, Sakata Y, Tsunoda R, Ogata Y,Seki A, Sumiyoshi T, Matsui M, Goto T, Tanabe Y, Sueda S, Kubo N, Momomura S, Ogawa H, Shimokawa H.
    • Journal Title

      Circ J

      Volume: (in press)

    • NAID

      10031151390

    • URL

      http://dx.doi.org/10.1253/circj.CJ-12-1486

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] Prognostic impact of blood ureanitrogen changes during hospitalization in patients with acute heart failure syndrome

    • Author(s)
      Miura M, Sakata Y, Nochioka K, Takahashi J, Takada T, Miyata S, Hiramoto T, Inoue K, Tamaki K, Shiba N, Shimokawa H.
    • Journal Title

      Circ J

      Volume: (in press)

    • NAID

      10031151384

    • URL

      http://dx.doi.org/10.1253/circj.CJ-12-1390

    • Data Source
      KAKENHI-PROJECT-22590766
  • [Journal Article] A comprehensive analysis of a missense mutation in the Rho-kinase gene that potentially causes coronary vasospastic ischemic heart disease in Japanese.

    • Author(s)
      Kamiunten H, Shimokawa H, et al.
    • Journal Title

      Circulation. (Publication is in preparation)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Journal Article] A comprehensive analysis of a missense mutation in the Rho-kinase gene that potentially causes coronary vasospastic ischemic heart disease in Japanese.

    • Author(s)
      Kamiunten H, Shimokawa H, et al.
    • Journal Title

      Circulation. (Publication is in preparation)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15256003
  • [Patent] PPARαアゴニストを含有する、肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明、佐藤公雄、佐藤大樹
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、佐藤大樹
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Patent] 生薬成分を含む肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Patent] セレノプロテインP活性阻害作用を有する成分を含有する、肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Patent] PPARαアゴニストを含有する、肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明、佐藤公雄、佐藤大樹
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、佐藤大樹
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 生薬成分を含む肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] セレノプロテインP活性阻害作用を有する成分を含有する、肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 不飽和複素5員環含有化合物を含有する肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Patent] 不飽和複素5員環含有化合物を含有する肺高血圧症の予防又は治療剤2017

    • Inventor(s)
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 生薬成分を含む肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明、佐藤公雄、黒澤亮
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、黒澤亮
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-160588
    • Filing Date
      2016-08-18
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] セレノプロテインP活性阻害作用を有する成分を含有する、肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-121034
    • Filing Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 不飽和複素5員環含有化合物を含有する肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-140474
    • Filing Date
      2016-07-15
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 肺高血圧症の検査方法2016

    • Inventor(s)
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 生薬成分を含む肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明, 徳山英利, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 徳山英利, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-120901
    • Filing Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 不飽和複素5員環含有化合物を含有する肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明, 大島吉輝, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 大島吉輝, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-140474
    • Filing Date
      2016-07-15
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] PPARαアゴニストを含有する、肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明、佐藤公雄、佐藤大樹
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、佐藤大樹
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-141942
    • Filing Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] 肺高血圧症の検査方法2016

    • Inventor(s)
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄、菊地順裕
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Patent] サイクロフィリンAによる心血管疾患の検査方法2016

    • Inventor(s)
      下川宏明、佐藤公雄
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Patent] 生薬成分を含む肺高血圧症の予防又は治療剤2016

    • Inventor(s)
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Holder
      下川宏明, 佐藤公雄, 黒澤亮
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-120901
    • Filing Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] サイクロフィリンAによる心血管疾患の検査方法2016

    • Inventor(s)
      下川宏明、佐藤公雄
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Patent] サイクロフィリンAによる心血管疾患の検査方法2014

    • Inventor(s)
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-239615
    • Filing Date
      2014-10-30
    • Acquisition Date
      2015-02-10
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Patent] 「サイクロフィリンAによる心血管疾患の検査方法」2013

    • Inventor(s)
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-10-29
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Patent] サイクロフィリンAによる心血管疾患の検査方法2013

    • Inventor(s)
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-10-29
    • Acquisition Date
      2015-02-10
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Patent] 「スタチンの用法、用量を決定する方法」2012

    • Inventor(s)
      下川宏明、田中眞一(国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、田中眞一(国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-12-19
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Patent] 「サイクロフィリンAによる心血管疾患の検査方法」2012

    • Inventor(s)
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-239615
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Patent] サイクロフィリンAによる心血管疾患の検査方法2012

    • Inventor(s)
      下川宏明、佐藤公雄
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄(国立大学法人東北大学)
    • Industrial Property Number
      2012-239615
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Patent] 「スタチンの用法、用量を決定する方法」2012

    • Inventor(s)
      下川宏明、田中眞一(国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、田中眞一(国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2011-197906
    • Filing Date
      2012-09-12
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Patent] 「サイクロフィリンAによる心血管疾患の検査方法」2012

    • Inventor(s)
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-239615
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Patent] サイクロフィリンAによる心血管疾患 の検査方法2012

    • Inventor(s)
      下川宏 明 、 佐 藤公雄
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄(国立大学法人 東北大学)
    • Industrial Property Number
      2012-239615
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Patent] 「サイクロフィリンAによる心血管疾患の検査方法」2012

    • Inventor(s)
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Holder
      下川宏明、佐藤公雄 (国立大学法人東北大学)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-239615
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Patent] スタチンの用法、用量を決定する方法2011

    • Inventor(s)
      下川宏明、田中眞一
    • Industrial Property Rights Holder
      下川宏明、田中眞一
    • Industrial Property Number
      2011-197906
    • Filing Date
      2011-09-12
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Patent] スタチンの用法・用量を決定する方法2011

    • Inventor(s)
      下川宏明・田中眞一
    • Industrial Property Rights Holder
      下川宏明・田中眞一
    • Filing Date
      2011
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Patent] スタチンの用法、用量を決定する方法2011

    • Inventor(s)
      下川宏 明 、田中眞一
    • Industrial Property Rights Holder
      下川宏 明 、田中眞一
    • Industrial Property Number
      2011-197906
    • Filing Date
      2011-09-12
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Patent] スタチンの用法、用量を決定する方法2011

    • Inventor(s)
      下川宏明、田中眞一
    • Industrial Property Rights Holder
      下川宏明、田中眞一
    • Industrial Property Number
      2011-197906
    • Filing Date
      2011-09-12
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Patent] 発明の名称 : 肺高血圧症のモデル動物作成法、肺高血圧症治療法、および治療薬物2006

    • Inventor(s)
      下川宏明, 小野栄夫, 菅村和夫, 石井直人, 佐藤公雄
    • Industrial Property Rights Holder
      下川宏明, 小野栄夫, 菅村和夫, 石井直人, 佐藤公雄
    • Industrial Property Number
      2006-008242
    • Filing Date
      2006-11-07
    • Acquisition Date
      2006-12-15
    • Data Source
      KAKENHI-PROJECT-18659218
  • [Presentation] Identification of celastramycin as a novel therapeutic agent for pulmonary arterial hypertension -High-throughput screening of 5,562 compounds-2018

    • Author(s)
      Kurosawa R, Satoh K, Kikuchi N, Satoh T, Omura J, Nogi M, Sunamura S, Ohtsuki T, Yaoita N, Abdul Hai Siddique M, Elias-Al-Mamun M, Shimizu T, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Presentation] Identification of celastramycin as a novel therapeutic agent for pulmonary arterial hypertension -High-throughput screening of 5,562 compounds-2018

    • Author(s)
      Kurosawa R, Satoh K, Kikuchi N, Satoh T, Omura J, Nogi M, Sunamura S, Ohtsuki T, Yaoita N, Abdul Hai Siddique M, Elias-Al-Mamun M, Shimizu T, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Presentation] Selenoprotein P promotes the development of pulmonary arterial hypertension-A Possible Novel Therapeutic Target-2018

    • Author(s)
      Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Elias-Al-Mamun M, Abdul Hai Siddique M, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Saito Y, Hoshikawa Y, Okada Y, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Presentation] Different roles of myocardial ROCK1 and ROCK2 in response to chronic pressure-overload in mice.2018

    • Author(s)
      Sunamura S, Satoh K, Shimizu T, Suzuki K, Ikeda S, Kudo S, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Ohtsuki T, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Presentation] Different roles of myocardial ROCK1 and ROCK2 in response to chronic pressure-overload in mice.2018

    • Author(s)
      Sunamura S, Satoh K, Shimizu T, Suzuki K, Ikeda S, Kudo S, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Ohtsuki T, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Presentation] Prognostic impacts of impaired coronary vasodilatation and enhanced coronary vasoconstricting responses in patients with angina and unobstructive coronary arteries.2018

    • Author(s)
      28.Suda A, Takahashi J, Hao K, Kikuchi Y, Shindo T, Sato K, Sugisawa J, Matsumoto Y, Miyata S, Sakata Y, Shimokawa H.
    • Organizer
      ESC Congress 2018 (Munich, Germany)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09413
  • [Presentation] Selenoprotein P promotes the development of pulmonary arterial hypertension-A Possible Novel Therapeutic Target-2018

    • Author(s)
      Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Elias-Al-Mamun M, Abdul Hai Siddique M, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Saito Y, Hoshikawa Y, Okada Y, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Presentation] Identification of Emetine as a Novel Therapeutic Agent for Pulmonary Hypertension in Rats -High-throughput Screening of 5,562 Compounds-2018

    • Author(s)
      Abdul Hai Siddique M, Satoh K, Kurosawa R, Elias-Al-Mamun M, Kikuchi N, Omura J, Satoh T, Nogi M, Sunamura S, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Presentation] Identification of Emetine as a Novel Therapeutic Agent for Pulmonary Hypertension in Rats -High-throughput Screening of 5,562 Compounds-2018

    • Author(s)
      Abdul Hai Siddique M, Satoh K, Kurosawa R, Elias-Al-Mamun M, Kikuchi N, Omura J, Satoh T, Nogi M, Sunamura S, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Presentation] ADAMTS8 Promotes the Development of pulmonary arterial hypertension and right ventricular failure-A possible novel therapeutic target-2018

    • Author(s)
      Satoh K, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Sunamura S, Ohtsuki T, Elias-Al-Mamun M, Abdul Hai Siddique M, Yaoita N, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Presentation] Identification of Emetine as a Novel Therapeutic Agent for Pulmonary Hypertension in Rats -High-throughput Screening of 5,562 Compounds-2018

    • Author(s)
      Abdul Hai Siddique M, Satoh K, Kurosawa R, Elias-Al-Mamun M, Kikuchi N, Omura J, Satoh T, Nogi M, Sunamura S, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15198
  • [Presentation] Selenoprotein P promotes the development of pulmonary arterial hypertension-A Possible Novel Therapeutic Target-2018

    • Author(s)
      Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Elias-Al-Mamun M, Abdul Hai Siddique M, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Saito Y, Hoshikawa Y, Okada Y, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Presentation] ADAMTS8 Promotes the Development of pulmonary arterial hypertension and right ventricular failure-A possible novel therapeutic target-2018

    • Author(s)
      Satoh K, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Sunamura S, Ohtsuki T, Elias-Al-Mamun M, Abdul Hai Siddique M, Yaoita N, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Presentation] ADAMTS8 Promotes the Development of pulmonary arterial hypertension and right ventricular failure-A possible novel therapeutic target-2018

    • Author(s)
      Satoh K, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Sunamura S, Ohtsuki T, Elias-Al-Mamun M, Abdul Hai Siddique M, Yaoita N, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Presentation] Identification of celastramycin as a novel therapeutic agent for pulmonary arterial hypertension -High-throughput screening of 5,562 compounds-2018

    • Author(s)
      Kurosawa R, Satoh K, Kikuchi N, Satoh T, Omura J, Nogi M, Sunamura S, Ohtsuki T, Yaoita N, Abdul Hai Siddique M, Elias-Al-Mamun M, Shimizu T, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Presentation] Different roles of myocardial ROCK1 and ROCK2 in response to chronic pressure-overload in mice.2018

    • Author(s)
      Sunamura S, Satoh K, Shimizu T, Suzuki K, Ikeda S, Kudo S, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Ohtsuki T, Shimokawa H.
    • Organizer
      World Symposium on Pulmonary Hypertension (2018年2月27~3月1日, Nice, France)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Presentation] Recent progress in vascular biology on pulmonary hypertension.2016

    • Author(s)
      Shimokawa H.
    • Organizer
      7th Scientific Meeting of the Asian Society of Vascular Biology
    • Place of Presentation
      Taiwan, Republic of China
    • Year and Date
      2016-10-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14F04902
  • [Presentation] Non-invasive Angiogenic Therapies with Acoustic Waves for Cardiovascular Diseases - Promising Approaches for the Future -2016

    • Author(s)
      伊藤健太、進藤智彦、畠中和明、尾形剛、黒澤亮、江口久美子、加賀谷裕太、西宮健介、圓谷隆治、羽尾清貴、瀧宏文、松本泰治、高橋潤、金井浩、下川宏明
    • Organizer
      第80回 日本循環器学会学術集会
    • Place of Presentation
      仙台(仙台国際センター)
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Molecular Mechanisms of Angiogenic Effects of Low-energy Shock Wave Therapy: Potential Involvement of Mechanotransduction Pathways2016

    • Author(s)
      畠中和明、伊藤健太、進藤智彦、尾形剛、黒澤亮、加賀谷裕太、江口久美子、下川宏明
    • Organizer
      第80回 日本循環器学会学術集会
    • Place of Presentation
      仙台(仙台国際センター)
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Recent progress in vascular biology on pulmonary hypertension.2016

    • Author(s)
      Shimokawa H.
    • Organizer
      7th Scientific Meeting of the Asian Society of Vascular Biology
    • Place of Presentation
      Taiwan, Republic of China
    • Year and Date
      2016-10-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02535
  • [Presentation] Low-energy Cardiac Shock Wave Therapy Ameliorates Left Ventricular Remodeling in Patients with Acute Myocardial Infarction2016

    • Author(s)
      加賀谷裕太、伊藤健太、高橋潤、松本泰治、白戸崇、圓谷隆治、羽尾清貴、西宮健介、進藤智彦、尾形剛、黒澤亮、江口久美子、畠中和明、宮田敏、下川宏明
    • Organizer
      第80回 日本循環器学会学術集会
    • Place of Presentation
      仙台(仙台国際センター)
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Low-energy cardiac shock wave therapy suppresses left ventricular remodeling after acute myocardial infarction―From bench to bedside―2015

    • Author(s)
      伊藤健太、高橋潤、松本泰治、圓谷隆治、羽尾清貴、西宮健介、加賀谷裕太、進藤智彦、尾形剛、黒澤亮、下川宏明
    • Organizer
      第79回 日本循環器学会学術集会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Circadian Variation of Rho-kinase Activity in Circulating Leukocytes in Patients with Vasospastic Angina2014

    • Author(s)
      Taro Nihei,Jun Takahashi, Yoku Kikuchi, Kiyotaka Hao, Yusuke Takagi, Ryuji Tsuburaya, Takashi Shirato, Yoshitaka Itoh, Yasuharu Matsumoto, Masaharu Nakayama, Kenta Ito, Hiroaki Shimokawa
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京、日本
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Extracorporeal Low-Energy Shock Wave Therapy Improves Left Ventricular Remodeling and Reduces Inflammatory Responses after Acute Myocardial Infarction in Rats2014

    • Author(s)
      Yuzuru Abe, Kenta Ito, Kiyotaka Hao, Kenichiro Hanawa, Tomohiko Shindo, Kensuke Nishimiya, Yuhi Hasebe, Hiroaki Yamamoto, Kimio Satoh, Kazuyoshi Kawakami, Hiroaki Shimokawa
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] 成熟期を迎えた心房細動アブレーション治療.2014

    • Author(s)
      福田浩二、下川宏明
    • Organizer
      第62回日本心臓病学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2014-09-28
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Presentation] DOES SYNTHESIZED LEAD V9 REFLECT LEFT ATRIAL ACTIVITY DURING ATRIAL FIBRILLATION?2014

    • Author(s)
      Xin Zhu, Yuki Yoshida, Daming Wei, Koji Fukuda, and Hiroaki Shimokawa
    • Organizer
      41st International Congress on Electrocardiology
    • Place of Presentation
      Bratislava, Slovakia
    • Year and Date
      2014-06-05
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Presentation] 重症心不全を呈した頻拍誘発性心筋症の2例2014

    • Author(s)
      瀬川将人、福田浩二、中野 誠、近藤正輝、長谷部雄飛、佐竹洋之、平野道基、下川宏明
    • Organizer
      第62回日本心臓病学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Presentation] 動に対するCTIブロックライン作成および房室結節アブレーションが奏功したCRT-D移植後のDCMの一例2014

    • Author(s)
      平野道基、福田浩二、中野 誠、近藤正輝、長谷部雄飛、佐竹洋之、下川宏明
    • Organizer
      第158回日本循環器学会東北地方会
    • Place of Presentation
      岩手医科大学附属循環器医療センター(岩手県盛岡市)
    • Year and Date
      2014-06-07
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Presentation] Circadian Variation of Rho-kinase Activity in Circulating Leukocytes in Patients with Vasospastic Angina Circulation Journal 2014, 78(Suppl. I) : I-5972014

    • Author(s)
      Taro Nihei, Jun Takahashi, Yoku Kikuchi, Kiyotaka Hao, Yusuke Takagi, Ryuji Tsuburaya, Takashi Shirato, Yoshitaka Itoh, Yasuharu Matsumoto, Masaharu Nakayama, Kenta Ito, Hiroaki Shimokawa
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Circadian Variation of Rho-kinase Activity Associated with Enhanced Coronary Reactivity in Patients with Vasospastic Angina2014

    • Author(s)
      Taro Nihei, Jun Takahashi, Yoku Kikuchi, Ryuji Tsuburaya, Takashi Shiroto, Yoshitaka Ito, Yasuharu Matsumoto, Masaharu Nakayama, Kenta Ito, Hiroaki Shimokawa
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25461038
  • [Presentation] Beneficial Effects of a Single Prophylactic Hemodialysis on Renal Function Worsening after Percutaneous Coronary Intervention in Patients with Severe CKD.2013

    • Author(s)
      Tsuburaya R, Takahashi J, Itoh Y, Shirato T, Yasuharu Matsumoto , Kenta Ito , Masaharu Nakayama , Hiroaki Shimokawa
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 急性心筋梗塞患者における冠動脈インターベンション未施行例の性差に関する検討-宮城県心筋梗塞対策協議会からの報告-2013

    • Author(s)
      羽尾清貴、高橋潤、二瓶太郎、円谷隆治、白戸崇、伊藤愛剛、松本泰治、中山雅晴、伊藤健太、安田聡、下川宏明
    • Organizer
      第6回日本性差医学・医療学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Prognostic impact of coronary revascularization therapy in patients with ischemic heart failure.2013

    • Author(s)
      (SY01: Progress in Coronary Revascularization: CABG andPCI for Severe Coronary Artery Disease) Takahashi J, Sakata Y, Nochioka K, Miura M, Takada T, Miyata S, Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 急性心筋梗塞の院内死亡率の性差に関する因子の検討-宮城県心筋梗塞対策協議会からの報告-2013

    • Author(s)
      伊藤愛剛、高橋潤、羽尾清貴、円谷隆治、白戸崇、松本泰治、二瓶太郎、中山雅晴、伊藤健太、安田聡、下川宏明
    • Organizer
      第6回日本性差医学・医療学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Circadian Variation of Rho-kinase Activity Associated with Enhanced Coronary Reactivity in Patients with Vasospastic Angina2013

    • Author(s)
      Taro Nihei, Jun Takahashi, Yoku Kikuchi, Ryuji Tsuburaya, Takashi Shiroto, Yoshitaka Ito, Yasuharu Matsumoto, Masaharu Nakayama, Kenta Ito, Hiroaki Shimokawa
    • Organizer
      ESC 2013
    • Place of Presentation
      Amsterdam - Netherlands
    • Data Source
      KAKENHI-PROJECT-25461038
  • [Presentation] Update on coronary spasm2013

    • Author(s)
      Shimokawa H
    • Organizer
      Rome Cardiology Forum 2012
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Chronic nitrate therapy in patients with vasospastic angina -Multicenter registry study of theJapanese Coronary Spasm Association-2013

    • Author(s)
      Takagi Y, Takahashi J, Yasuda S, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Gotoh T, Tanabe Y, Ogawa H, Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Improved emergency care of acute myocardial infarction during the Great East Japan Earthquake Disaster -The Miyagi AMI Registry Study-2013

    • Author(s)
      Hao K, Takahashi J, Nihei T, Tsuburaya R, Shirato T, Itoh Y, Matsumoto Y, Nakayama M, Kenta Ito,Yasuda S, Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Circadian variationof Rho-kinase activity in patients with vasospastic angina.2013

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Hao K, Takagi Y, Tsuburaya R, Shirato T, Itoh Y, Matsumoto Y, Nakayama M, Ito K, Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Recent progress in endothelial research2013

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at Royal Adelaide Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2013-04-30
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] 冠攣縮性狭心症患者における性別・年代別の臨床像と予後の違い2013

    • Author(s)
      川名暁子、高橋潤、高木祐介、安田聡、角田隆輔、緒方康博、関敦、住吉徹哉、松井幹之、後藤敏和、田辺恭彦、末田章三、久保典史、百村伸一、小川久雄、下川宏明
    • Organizer
      第6回日本性差医学・医療学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Important Role of Adventitial Vasa Vasorum in the Pathogensis of Coronary Hyperconstricting Responses After Drug-Eluting Stent Implantation in Pigs in Vivo2013

    • Author(s)
      Kensuke Nishimiya, Yasuharu Matsumoto, Jun Takahashi, Tomohiko Shindo, Kenichiro Hanawa, Yuhi Hasebe, Ryuji Tsuburaya, Takashi Shiroto, Kenta Ito, Hatsue Ishibashi-Ueda, Satoshi Yasuda, and Hiroaki Shimokawa
    • Organizer
      ESC Congress 2013
    • Place of Presentation
      Amsterdam, Nederland
    • Data Source
      KAKENHI-PROJECT-24790732
  • [Presentation] Derived 18-lead ECG in analysis of left-to-right atrial dominant frequency gradient during atrial fibrillation2013

    • Author(s)
      朱 欣、魏大名、福田浩二、下川宏明
    • Organizer
      第29回心電情報処理ワークショップ
    • Place of Presentation
      越後湯沢・ナスパニューオータニ
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Presentation] A SIMPLE ATRIAL FIBRILLATORY WAVE RECONSTRUCTION METHOD FOR FREQUENCY ANALYSIS OF ATRIAL FIBRILLATION USING SINGLE-LEAD ECG2013

    • Author(s)
      Zhu X, Wei D, Fukuda K, Shimokawa H
    • Organizer
      IASTED International Conference on Biomedical Engineering
    • Place of Presentation
      Innsbruck Congress, Innsbruck, Austria
    • Data Source
      KAKENHI-PROJECT-24500369
  • [Presentation] 低出力体外衝撃波治療2013

    • Author(s)
      伊藤健太、下川宏明
    • Organizer
      第19回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Nitrates as a concomitant therapy in patients with vasospastic angina -A report from the Japanese Coronary Spasm Association-2013

    • Author(s)
      (RT12: How to Manage Intractable Coronary Artery Spasm)Takagi Y, Takahashi J, Yasuda S, Ogata Y, Sumiyoshi T, Goto T, Ogawa H,Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Characteristics of patients with acute myocardial infarction who did not receive primary PCI -A report from the Miyagi AMI Study-2013

    • Author(s)
      Hao K, TakahashiJ, Nihei T, Tsuburaya R, Shirato T, ItohY, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Age-dependent differences in clinical characteristics and outcomes of female patients withvasospastic angina.2013

    • Author(s)
      Kawana A, TakahashiJ, Takagi Y, Yasuda S, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Gotoh T, Tanabe Y, Sueda S, Kubo N, Momomura S, Ogawa H, Shimokawa H.
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Circadian variation of Rho-kinase activity associated with enhanced coronary reactivity in patients with vasospastic angina2013

    • Author(s)
      .Nihei T, Takahashi J, Kikuchi Y, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama Y, Ito K, Shimokawa H.
    • Organizer
      uropean Society of Cardiology 2013
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Important Role of Adventitial Vasa Vasorum in the Pathogensis of Coronary Hyperconstricting Responses After Drug-Eluting Stent Implantation in Pigs in Vivo2013

    • Author(s)
      Kensuke Nishimiya, Yasuharu Matsumoto, Jun Takahashi, Tomohiko Shindo, Kenichiro Hanawa, Yuhi Hasebe, Ryuji Tsuburaya, Takashi Shiroto, Kenta Ito, Hatsue Ishibashi-Ueda, Satoshi Yasuda, and Hiroaki Shimokawa
    • Organizer
      American heart association scientific session 2013
    • Place of Presentation
      Dallas, USA
    • Data Source
      KAKENHI-PROJECT-24790732
  • [Presentation] 冠微小循環と内皮由来過分極因子としての過酸化水素2013

    • Author(s)
      矢田豊隆、下川宏明
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PROJECT-22300162
  • [Presentation] Rho-kinase as an important new therapeutic target in cardiovascular medicine2013

    • Author(s)
      Shimokawa H.
    • Organizer
      Invited lecture at the San Raffaele University
    • Place of Presentation
      Milano, Italy
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Circadian variation of Rho-kinase activity associated with enhanced coronary reactivity in patients with vasospastic angina2013

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama Y, Ito K, Shimokawa H.
    • Organizer
      European Society of Cardiology 2013
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] European Society of Cardiology Congress2012

    • Author(s)
      Shimokawa H.
    • Organizer
      The Great East Japan Earthquake Disaster and cardiovascular diseases
    • Place of Presentation
      Munich, Germany<Hotline Session>
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] The Great East Japan Earthquake Disaster and cardiovascular diseases2012

    • Author(s)
      Shimokawa H
    • Organizer
      European Society of Cardiology Congress
    • Place of Presentation
      Munich, Germany
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Present status & future perspectives of heart failure in Japan2012

    • Author(s)
      Shimokawa H.
    • Organizer
      Invited lecture at the Flinders Medical Center
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-02
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Rho-kinase Activity in Circulating Leukocytes as a Novel Biomarker in Patients with Chronic Heart Failure2012

    • Author(s)
      YZhulanqiqige Do. e, Yoshihiro Fukumoto, Koichiro Sugimura, Yutaka Miura, Saori Yamamoto, Shunsuke Tatebe, Tatsuo Aoki, Kotaro Nochioka, Kimio Satoh, Hiroaki Shimokawa
    • Organizer
      第76回日本循環器学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Presentation] <Symposium: Update on coronary vasomotion>Update on coronary spasm2012

    • Author(s)
      Shimokawa H.
    • Organizer
      Rome Cardiology Forum 2012
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Acute heart failure caused by biventricular involvement of Takotsubo cardiomyopathy.2012

    • Author(s)
      Tsuburaya R, Takahashi J, Ito Y, Takagi Y, Matsumoto Y, Nakayama M, Ito K, Shimokawa H.
    • Organizer
      第16回日本心不全学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Recent progress in endothelial research2012

    • Author(s)
      Shimokawa H.
    • Organizer
      Invited lecture at Royal Adelaide Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-04-30
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Rho-kinase as an important new therapeutic target in cardiovascular medicine.2012

    • Author(s)
      Shimokawa H.
    • Organizer
      Invited lecture at the San Raffaele University
    • Place of Presentation
      Milano, Italy
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Symposium: Update on coronary vasomotion2012

    • Author(s)
      Hiroaki Shimokawa
    • Organizer
      Rome Cardiology Forum 2012
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2012-04-01
    • Invited
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] The Great East Japan Earthquake Disaster and cardiovascular diseases2012

    • Author(s)
      Shimokawa H
    • Organizer
      European Society of Cardiology Congress 2012 <Hotline Session>
    • Place of Presentation
      Munich, Germany
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Present status & future perspectives of heart failure in Japan2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the Flinders Medical Center
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-02
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Coronary spasm in 2012: Mechanisms and treatment2012

    • Author(s)
      Shimokawa H
    • Organizer
      Australia & New Zealand Meeting
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] <Main Session: Rho/Rho-kinase Signaling in Health and Diseases>Role of Rho/Rho-kinase pathway in the cardiovascular system2012

    • Author(s)
      Shimokawa H.
    • Organizer
      6th European Congress of Pharmacology
    • Place of Presentation
      Granada, Spain
    • Year and Date
      2012-07-19
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Increased Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake disaster2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Ito Y, Tsuburaya R, Takagi Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      European Society of Cardiology Congress 2012
    • Place of Presentation
      Munich, Germany
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Role ofRho/Rho-kinase pathway in the cardiovascular system2012

    • Author(s)
      Shimokawa H
    • Organizer
      6th European Congress of Pharmacology <Main Session:Rho/Rho-kinase Signaling in Health and Diseases>
    • Place of Presentation
      Granada, Spain
    • Year and Date
      2012-07-19
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Recent progress in endothelial research2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at Royal Adelaide Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-04-30
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Controlling Nutritional Status Score (CONUTS) is a Useful Prognostic Marker in Stage B Heart Failure Patients ; Interim Analysis of the CHART-2 Study2012

    • Author(s)
      後岡広太郎、柴信行、高橋潤、三浦正暢、高田剛、下川宏明
    • Organizer
      第76回日本循環器学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Update on coronary spasm2012

    • Author(s)
      Shimokawa H
    • Organizer
      Rome Cardiology Forum 2012, <Symposium:Update on coronary vasomotlon>
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2012-05-30
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Rho-kinase as an important CV therapeutic target2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at Medical Grand Round of the Queen Elizabeth Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Clinical implications of coronary spasm provocation tests -multicenter registry study of the Japanese Coronary Spasm Association-.2012

    • Author(s)
      Takagi Y, Takahashi J, Nihei T, Yasuda S, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Gotoh T,Tanbae Y, Ogawa H, Shimokawa H.
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Recent progress in endothelial research2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the CardiologyAcademic Meeting of the QueenElizabeth Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Novel clinical risk score for prediction of cardiac events in VSA patients -a report from the Japanese Coronary Spasm Association-.2012

    • Author(s)
      Takagi Y, Takahashi J, Nihei T, Yasuda S, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Gotoh T,Tanbae Y, Ogawa H, Shimokawa H.
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Present status & future perspectives ofheart failure in Japan2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the Flinders Medical Center
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-02
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Enhanced rho-kinase activity in circulating neutrophils of patients with vasospasticangina after the Great East Japan Earthquake. (#9574)2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Hao K, Takagi Y, Tsuburaya R, Shiroto T, ItoY, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      American Heart Association (AHA) Scientific Sessions
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Influence of coexisting heart failure on non-performance of primary percutaneous coronary intervention in patients with acutemyocardial infarction.2012

    • Author(s)
      Hao K, Takahashi J, Tsuburaya R, Shiroto T, Ito Y, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      第16回日本心不全学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 虚血性心血管疾患に対する低出力体外衝撃波治療2012

    • Author(s)
      伊藤健太、伊藤愛剛、福本義弘、下川宏明
    • Organizer
      H23年度衝撃波シンポジウム
    • Place of Presentation
      柏
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Presentation] Increased rho-kinase activity in patients with vasospastic angina after the East Japan EarthquakeDisaster.2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Itoh Y, Nakayama M, Tsuburaya R, Ohhashi J, Takagi Y, Itoh K, Yasuda S, Shimokawa H.
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Recent progress in endothelial research2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the Cardiology Academic Meeting of the Queen Elizabeth Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Recent progress in endothelial research2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the Cardiology Academic Meeting of the Queen Elizabeth Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Coronary spasm in 2012: Mechanisms and treatment.2012

    • Author(s)
      Hiroaki Shimokawa
    • Organizer
      Invited lecture at the Cardiac Society of Australia & New Zealand Meeting
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-04-30
    • Invited
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Rho-kinase as an important CV therapeutic target2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at Medical Grand Round of the Queen Elizabeth Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Rho-kinase as an important new therapeutic target in cardiovascular medicine2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited Lecture at the San Raffaele University
    • Place of Presentation
      Milano, Italy
    • Year and Date
      2012-05-30
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Prognostic impact of long-acting nitrate therapy in patients with vasospastic angina -a report from the Japanese Coronary Spasm Association-.2012

    • Author(s)
      Takagi Y, TakahashiJ, Nihei T, Yasuda S, Tsunoda R, Ogata Y, Seki A, Sumiyoshi T, Matsui M, Gotoh T,Tanbae Y, Ogawa H, Shimokawa H.
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Cessasion of spironolactone worsens long-term prognosis of heartfailure patients.2012

    • Author(s)
      Nakayama M, Takahashi J, Ito K, Matsumoto Y, Ito Y, Tsuburaya R, Shiroto T, Takagi Y, Hao K, Shimokawa H.
    • Organizer
      第16回日本心不全学会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 冠攣縮性狭心症における性差:冠攣縮研究会における知見2012

    • Author(s)
      川名暁子、高橋潤、安田聡、高木祐介、角田康夫、緒方康博、関敦、住吉徹哉、松井幹之、後藤敏和、田辺恭彦、末田章三、久保典史、百村伸一、小川久雄、下川宏明
    • Organizer
      第5回日本性差医学・医療学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Rho-kinase as an important CV therapeutic target2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at Medical Grand Round of the Queen Elizabeth Hospital
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Coronary spasm in 2012: Mechanisms and treatment2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the Cardiac Society of Australia & New Zealand Meeting
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Coronary spasm in 2012: Mechanisms and treatment2012

    • Author(s)
      Shimokawa H
    • Organizer
      Invited lecture at the Cardiac Society of Australia & New Zealand Meeting
    • Place of Presentation
      Adelaide, Australia
    • Year and Date
      2012-05-01
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Role of Rho/Rho-kinase pathway in the cardiovascular system2012

    • Author(s)
      Shimokawa H.
    • Organizer
      6th European Congress of Pharmacology
    • Place of Presentation
      Granada, Spain
    • Year and Date
      2012-07-19
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Increased Rho-kinase activity in patients with vasospastic angina after the Great East Japan Earthquake disaster.2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Ito Y, Tsuburaya R, Takagi Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      European Society of Cardiology Congress
    • Place of Presentation
      Munich, Germany
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Enhanced rho-kinase activity in circulating neutrophils of patients with vasospasticangina after the Great East Japan Earthquake.2012

    • Author(s)
      Nihei T, Takahashi J, Kikuchi Y, Hao K, Takagi Y, Tsuburaya R, Shiroto T, ItoY, Matsumoto Y, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      American Heart Association
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Beneficial effects of a single prophylactic hemodialysis onrenal function worsening after percutaneous coronary intervention in patients with severe CKD.2012

    • Author(s)
      Tsuburaya R, Takahashi J, Takagi Y, Ohhashi J, Itoh Y, Matsumoto Y, Takeda M, Nakayama M, Itoh K, Yasuda S, Shimokawa H.
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Involvement of Rho-kinase Activation in the Pathogenesis of coronary hyperconstricting responses by drug-eluting stents in patients with coronary artery disease.2011

    • Author(s)
      Aizawa K, Yasuda S, Takahashi J, Takii T, Kikuchi Y, Tsuburaya R, Ito Y, Ito K, Nakayama M, Takeda M, Shimokawa H.
    • Organizer
      日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Usefulness of Rho-kinase activity in circulating neutrophils for disease activity assessment of vasospastic angina.2011

    • Author(s)
      9.Kikuchi Y, Aizawa K, Yasuda S, Tsuburaya R, Ito Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H.
    • Organizer
      American Heart Association (AHA) Scientific Sessions
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23591026
  • [Presentation] Morphological analysis of the coronary arterial wall of patients withvasospastic angina pectoris with optical coherence tomography.2011

    • Author(s)
      Takeda M, Takahashi J, Nakayama M, Ito K, Yasuda S, Shimokawa H.
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 虚血性心血管疾患に対する新しい非侵襲的血管新生療法:低出力体外衝撃波治療2011

    • Author(s)
      羽尾清貴, 伊藤健太, 芹澤玄, 福本義弘, 佐藤成, 下川宏明
    • Organizer
      第59回日本心臓病学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Presentation] 心腎症候群を合併した心不全症例における持続腎代替療法の有用性.2011

    • Author(s)
      高橋潤、安田聡、柴信行、下川宏明
    • Organizer
      第59回日本心臓病学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Rho-kinase activity in circulating neutrophils for diagnosis and disease activity assessment of vasospastic angina.2011

    • Author(s)
      Kikuchi Y, Aizawa K, Yasuda S, Tsuburaya R, Ito Y, Matsumoto Y, Takeda M, Nakayama M, Ito K, Takahashi J, Shimokawa H.
    • Organizer
      日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Crucial role of SmgGDS in the molecular mechanisms of the pleiotropic effects of HMG-CoA reductase inhibitors.2011

    • Author(s)
      Tanaka S, Nochioka K, Shimokawa H, et al.
    • Organizer
      American Heart Association (AHA)
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Continuous renal replacement therapy in patients with acute decompensated heart failure and cardio-renal syndrome.2011

    • Author(s)
      Takahashi J, YasudaS, Shiba N, Nakayama M, Shimokawa H.
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Multiple mechanisms are involved in enhanced endothelium-derived hyperpolarizing factor (EDHF)-mediated responses in microvessels in mice-A clue for novel strategy for vascular protection-2011

    • Author(s)
      Ohashi J, Shimokawa H, et al
    • Organizer
      American Heart Association
    • Place of Presentation
      Orlando, USA
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲性血管新生療法2011

    • Author(s)
      伊藤健太、伊藤愛剛、菊地翼、羽尾清貴、円谷隆治、相澤健太郎、高橋潤、武田守彦、中山雅晴、松本泰治、高木祐介、福本義弘、安田聡、下川宏明
    • Organizer
      第20回日本心血管インターベンション治療学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Presentation] Low-energy extracorporeal shock wave therapy as a new and non-invasive angiogenic strategy for cardiovascular diseases2011

    • Author(s)
      Ito K, Kikuchi Y, Ito Y, Tsuburaya R, Aizawa K, Hao K, Takahashi J, Takeda M, Nakayama M, Fukumoto Y, Yasuda S, Shimokawa H.
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Presentation] Increased incidence of heart failure in the Tohoku Earthquake - Initial report from the Tohoku University Hospital-2011

    • Author(s)
      Takahashi J, Yasuda S, nakayama M, Ito Y, Ito K, Fukuda K, Fukumoto Y, Shiba N, Shimokawa H.
    • Organizer
      第15回日本心不全学会
    • Place of Presentation
      鹿児島市
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲性血管新生療法2011

    • Author(s)
      伊藤愛剛, 伊藤健太, 菊地翼, 羽尾清貴, 円谷隆治, 相澤健太郎, 高橋潤, 武田守彦, 中山雅晴, 松本泰治, 高木祐介, 福本義弘, 安田聡, 下川宏明
    • Organizer
      第17回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590922
  • [Presentation] Long-term treatment with eicosapentaenoic acid ameliorates myocardial ischemia-reperfusion injury in pigs in vivo -Potential involvement of Rho-kinase pathway-2011

    • Author(s)
      Gao JY, Yasuda S, Tsuburaya R, Ito Y, Aizawa K, Kikuchi Y, Ito K, Shimokawa H.
    • Organizer
      日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Optical Coherence Tomographyを用いた攣縮を生じる冠動脈の微細構造の解析:局所性冠攣縮とびまん性冠攣縮の差異.2011

    • Author(s)
      武田守彦、高橋潤、伊藤健太、中山雅晴、安田聡、下川宏明
    • Organizer
      第59回日本心臓病学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Long-term treatment with nifedipine suppresses coronary hyperconstricting responses induced by paclitaxel-eluting stent in pigs in vivo -Possible involvement of Rho-kinase.2011

    • Author(s)
      Tuburaya R, Yasuda S, Aizawa K, Gao JY, Ito Y, Shiroto T, Ito K, Ishibashi-Ueda H, Shimokawa H.
    • Organizer
      日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Multiple mechanisms are involved in enhanced endothelium-derived hyperpolarizing factor (EDHF)-mediated responses in microvessels in mice-A clue for novel strategy for vascular protection-2011

    • Author(s)
      Ohashi J, Shimokawa H, et al
    • Organizer
      American Heart Association
    • Place of Presentation
      Orlando, USA
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Current Status and Future Perspectives of Diastolic Heart Failure in Japan-Rho-kinase as a Possible Therapeutic Target-2010

    • Author(s)
      Yoshihiro Fukumoto, Yutaka Miura, Shigefumi Fukui, Tatsuo Aoki, Toshiro Miura, Masunori Matsuzaki, Kazunori Shimada, Yoshitaka Iwama, atsutoshi Takagi, Hiroyuki Daida, Takaki Tsutsumi, Akira Yamada, Shintaro Kinugawa, Hiroyuki Tsutsui, Masanori Asakura, Hitonobu Tomoike, 1Nobuyuki Shiba, Hiroaki Shimokawa
    • Organizer
      第74回日本循環器学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-05
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Presentation] Long-term treatment with nifedipine suppresses coronary hyperconstricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo : possible involvement of rho-kinase pathway.2010

    • Author(s)
      Tsuburaya R, Yasuda S, Aizawa K, Gao J, Ito Y, Shiroto T, Ito K, Ishibashi-Ueda H, Shimokawa H.
    • Organizer
      Annual Scientific Meeting of the American Heart Association
    • Place of Presentation
      Chicago, USA.
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] 心腎症候群を合併した急性心不全症例における持続腎代替療法の検討.2010

    • Author(s)
      高橋潤、安田聡、柴信行、中山雅晴、下川宏明
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Endothelial research for 25 years : From regenerated endothelium to trinle NOSs-deficient mice. (invited lecture)2010

    • Author(s)
      Shimokawa H.
    • Organizer
      4^<th> Asian Society of Vascular Biology
    • Place of Presentation
      Hong Kong China.
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] Long-term treatment with eicosapentaenoic acid ameliorates myocardial ischemia-reperfusion injury in pigs in vivo -A potential role of Rho-kinase pathway-.2010

    • Author(s)
      Gao JY, Yasuda S, Tsuburaya R, Ito Y, Aizawa K, Kikuchi Y, Ito K, Shimokawa H.
    • Organizer
      Annual Scientific Meeting of the American Heart Association;
    • Place of Presentation
      Chicago, USA.
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Enhanced Rho-kinase activity in circulating neutrophils in patients with vasospastic angina-Possible usefulness for diagnosis and disease activity assessment-.2010

    • Author(s)
      Kikuchi Y, Aizawa K, Yasuda S, Tsuburaya R, Ito Y, Nakayama M, Takeda M, Ito K, Takahashi J, Shimokawa H.
    • Organizer
      Annual Scientific Meeting of the American Heart Association;
    • Place of Presentation
      Chicago, USA.
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] A hybrid strategy with percutaneous coil embolization and re-CABG for giantcoronary aneurysm in a patient undergoneDor procedure.2010

    • Author(s)
      Takahashi J, Yasuda S, Takeda M, Ito Y, Tsuburaya R, Takagi Y, Oda K, Kawamoto S, takase B, Tabayashi K, Shimokawa H.
    • Organizer
      第19回日本心血管インターベンション治療学会(CVIT2010)
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] 腹部大動脈瘤患者における術前冠動脈造影及び冠血行再建術の有用性.2010

    • Author(s)
      武田守彦、高橋潤、伊藤健太、中山雅晴、安田聡、下川宏明
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] Endothelial research for 25 years : From regenerated endothelium to triple NOSs-deficient mice.2010

    • Author(s)
      Shimokawa H.
    • Organizer
      4^<th> Scientific Meeting of the Asian Society for Vascular Biology
    • Place of Presentation
      HK(Invited lecture)
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Rho-kinase as a new therapeutic target in cardiovascular medicine.2010

    • Author(s)
      Shimokawa H.
    • Organizer
      The 54^<th> Annual Scientific Meeting of the Korean Society of Cardiology (October 7-9, 2010, Seoul, Korea)
    • Place of Presentation
      韓国、ソウル
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] 心腎症候群を合併した急性心不全症例における持続腎代替療法の検討2010

    • Author(s)
      高橋潤、安田聡、柴信行、中山昌明、下川宏明
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] (東北大学病院循環器内科)肺高血圧症における新たな分子治療標的 : Rhoキナーゼの重要性2010

    • Author(s)
      福本義弘下川宏明
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Presentation] 肺高血圧症における新たな分子治療標的:Rh0キナーゼの重要性2010

    • Author(s)
      福本義弘、下川宏明
    • Organizer
      第58回 日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Presentation] Life-threatening complications after sirolimus-eluting stent implantation.2010

    • Author(s)
      Takeda M, Takahashi J, Ito K, Nakayama M, Yasuda S, Shimokawa H.
    • Organizer
      第19回日本心血管インターベンション 治療学会(CVIT2010)
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22590766
  • [Presentation] (東北大学病院循環器内科)三浦俊郎、松崎益徳(山口大学)島田和典、岩間義孝、高木篤俊、代田浩之(順天堂大学)朝倉正紀、友池仁暢(国立循環器病センター)堤孝樹、山田明(飯塚病院)絹川真太郎、筒井裕之(北海道大学)わが国の慢性心不全の成因における糖尿病の意義2010

    • Author(s)
      福本義弘、三浦裕、福井重文、柴信行、下川宏明
    • Organizer
      第58回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-18
    • Data Source
      KAKENHI-PROJECT-21590884
  • [Presentation] Rho-kinase is an important therapeutic target in cardiovascular medicine.2009

    • Author(s)
      Shimokawa H
    • Organizer
      International Symposium on Atherosclerosis
    • Place of Presentation
      アメリカボストン
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Presentation] Rho-kinase pathway plays an important role in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stent.2009

    • Author(s)
      Shiroto T, Yasuda S, Tsuburaya R, Ito Y, Ishibashi-Ueda H, Ito K, Takahashi J, Shimokawa H.
    • Organizer
      Annual Scientific Meeting of the American Heart Association
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Current Status and Future Perspectives of Diastolic Heart Failure in Japan-Possible Importance of Metabolic Syndrome-2009

    • Author(s)
      Yoshihiro Fukumoto, Yutaka Miura, Shigefumi Fukui, Toshiro Miura, Masunori Matsuzaki, Kazunori Shimada, Yoshitaka Iwama, Atsutoshi Takagi, Hiroyuki Daida, Takaki Tsutsumi, Akira Yamada, Shintaro Kinugawa, Hiroyuki Tsutsui, Masanori Asakura, Hitonobu Tomoike, Hiroaki Shimokawa
    • Organizer
      第73回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-21
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] ブタ心筋虚血再灌流傷害後の左室リモデリングに対する体外衝撃波治療の抑制効果2009

    • Author(s)
      伊藤愛剛、伊藤健太、白戸崇、円谷隆治、高軍毅、武田守彦、福本義弘、安田聡、下川宏明
    • Organizer
      第147回日本循環器学会東北地方会
    • Place of Presentation
      仙台
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Presentation] Evidence for Rho-kinase Activation in Patients with Pulmonary Arterial Hypertension2009

    • Author(s)
      Doe Zhulanqiqige, Yoshihiro Fukumoto, Aya Takaki, Shunsuke Tawara, Junko Ohashi, Makoto Nakano, Tomohiro Tada, Kenya Saji, Kohichiro Sugimura, Hiroshi Fujita, Yasushi Hoshikawa, Jun Nawata, Takashi Kondo, Hiroaki Shimokawa
    • Organizer
      第73回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-20
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Rho-kinase is an important therapeutic target in cardiovascular medicine2009

    • Author(s)
      Shimokawa H
    • Organizer
      International Symposium on Atherosclerosis
    • Place of Presentation
      アメリカ ボストン
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Genetic Deletion of OX40 Ligand Suppresses the Development of Atherosclerosis in Apolipoprotein E-Deficient Mice2009

    • Author(s)
      中野誠, 下川宏明, 他
    • Organizer
      日本循環器学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2009-03-20
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Presentation] Genetic Deletion of OX40 Ligand Suppresses the Development of Atherosclerosis in Anolipoprotein E-Deficient Mice2009

    • Author(s)
      中野誠、下川宏明, 他
    • Organizer
      日本心脈管作動物質学会
    • Place of Presentation
      岡山大学50周年記念講堂
    • Year and Date
      2009-02-06
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Presentation] Non-invasive-revascularization by CSWT in chronic ischemia ; animal and clinical studies.2009

    • Author(s)
      Shimokawa H
    • Organizer
      European Society of Cardiology Congress 2009
    • Place of Presentation
      スペインバルセロナ
    • Year and Date
      2009-08-29
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Presentation] Non-invasive revascularization by CSWT in chronic ischemia ; animal and clinical studies2009

    • Author(s)
      Shimokawa H
    • Organizer
      European Society of Cardiology Congress 2009
    • Place of Presentation
      スペイン バルセロナ
    • Year and Date
      2009-08-29
    • Data Source
      KAKENHI-PLANNED-20117009
  • [Presentation] Differential Roles of Progenitor Cells in Cardiovascular Disease2009

    • Author(s)
      中野誠、下川宏明, 他
    • Organizer
      日本循環器学会
    • Place of Presentation
      リーガロイヤルホテル大阪
    • Year and Date
      2009-03-20
    • Data Source
      KAKENHI-PROJECT-20659122
  • [Presentation] Diabetes Mellitus Accelerates Left Ventricular Diastolic Dysfunction through Activation of Renin-Angiotensin System in Hypertensive Rats2009

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Kenya Saji, Jun Nawata, Kohichiro Sugimura, Yutaka Miura, Yutaka Kagaya, Hiroaki Shimokawa
    • Organizer
      第73回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-22
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Rho-kinase pathway plays an important role in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stent.2009

    • Author(s)
      Shiroto T, Yasuda S, Tsuburaya R, Ito Y, Ishibashi-Ueda H, Ito K, Takahashi J, Shimokawa H.
    • Organizer
      Annual Scientific Meeting of the American Heart Association;
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PROJECT-20590875
  • [Presentation] Extracorporeal cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs in vivo2009

    • Author(s)
      Ito Y, Ito K, Shiroto T, Tsuburaya R, Gao JY, Kikuchi Y, Aizawa K, Takeda M, Yasuda H, Shimokawa H
    • Organizer
      第73回日本循環器学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-21
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Presentation] Diabetes mellitus exacerbates left ventricular diastolic dysfunction through activation of rennin-angiotensin system in hypertensive rats2008

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Jun Nawata, Koichiro Sugimura, Tsuyoshi Shinozaki, Yutaka Kagaya, Hiroaki Shimokawa
    • Organizer
      ESC Congress 2008
    • Place of Presentation
      Munich
    • Year and Date
      2008-09-01
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] 肺高血圧症における新たな分子治療標的 : Rhoキナーゼの重要性2008

    • Author(s)
      福本義弘、下川宏明
    • Organizer
      第56回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-08
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Diabetes Mellitus Accelerates Left Ventricular Diastolic Dysfunction through Activation of Renin-Angiotensin System in Hypertensive Rats2008

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Kenya Saji, Jun Nawata, Kohichiro Sugimura, Yutaka Miura, Yutaka Kagaya, Hiroaki Shimokawa
    • Organizer
      Scientific Sessions of the American Heart Association 2008
    • Place of Presentation
      New Orleans
    • Year and Date
      2008-11-11
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Extracorporeal cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs2008

    • Author(s)
      Ito Y, Ito K, Shiroto T, Tsuburaya R, Gao J, Kikuchi Y, Aizawa K, Takeda M, Yasuda S, Shimokawa H
    • Organizer
      American Heart Association Scientific Session 2008
    • Place of Presentation
      米国ニューオーリンズ
    • Year and Date
      2008-11-09
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Presentation] 低出力体外衝撃波を用いた非侵襲性血管新生療法の開発2008

    • Author(s)
      伊藤健太、福本義弘、安田聡、下川宏明
    • Organizer
      第56回日本心臓病学会学術集会シンポジウム「心血管再生医療の現状と展望」
    • Place of Presentation
      東京
    • Year and Date
      2008-09-11
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Presentation] パネルディスカッション2肺高血圧の診断と治療の進歩肺高血圧症における新たな分子治療標的Rhoキナーゼの重要性2008

    • Author(s)
      福本義弘、下川宏明
    • Organizer
      第56回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-08
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] 肺高血圧症患者におけるRhoキナーゼ活性の亢進2008

    • Author(s)
      道額珠蘭其其格、福本義弘、縄田淳、田原俊介、中野誠、多田智洋、佐治賢哉、藤田央、星川康、近藤丘、下川宏明
    • Organizer
      第56回日本心臓病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-10
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Diabetes Mellitus Accelerates Left Ventricular Diastolic Dysfunction through Activation of Renin-angiotensin System in Hypertensive Rats2008

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Kenya Saji, Jun Nawata, Yutaka Kagaya, Hiroaki Shimokawa
    • Organizer
      第72回日本循環器学会総会・学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Evidence for Rho-kinase Activation in Patients with Pulmonary Hypertension2008

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Kenya Saji, Jun Nawata, Zhulanqiqige Do.e, Yoshihiro Fukumoto, Aya Takaki, Shunsuke Tawara, Junko Ohashi, Makoto Nakano, Tomohiro Tada, Kenya Saji, Kohichiro Sugimura, Hiroshi Fujita, Jun Nawata, Yasushi Hoshikawa, Takashi Kondo, Hiroaki Shimokawa
    • Organizer
      Scientific Sessions of the American Heart Association 2008
    • Place of Presentation
      New Orleans
    • Year and Date
      2008-11-11
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Inhibition of Rho-kinase Ameliorates Diastolic Heart Failure in Hypertensive Rats2008

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Kenya Saji, Jun Nawata, Shunsuke Tawara, Yutaka Kagaya, Hiroaki Shimokawa
    • Organizer
      第72回日本循環器学会総会・学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2008-03-29
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] Extracorporeal cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs in vivo2008

    • Author(s)
      Ito Y, Ito K, Shiroto T, Tsuburaya R, Gao JY, Yasuda H, Shimokawa H
    • Organizer
      The European Society of Cardiology Congress 2008
    • Place of Presentation
      ドイツミュンヘン
    • Year and Date
      2008-08-31
    • Data Source
      KAKENHI-PROJECT-19590801
  • [Presentation] Long-Term Inhibition of Rho-kinase Ameliorates Diastolic Heart Failure in Hypertensive Rats2007

    • Author(s)
      Shigefumi Fukui, Yoshihiro Fukumoto, Jun Suzuki, Kenya Saji, Jun Nawata, Shunsuke Tawara, Tsuyoshi Shinozaki, Yutaka Kagaya, Hiroaki Shimokawa
    • Organizer
      Scientific Sessions of the American Heart Association 2007
    • Place of Presentation
      Orlando
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19590803
  • [Presentation] 低出力体外衝撃波治療と心臓リハビリテーション.

    • Author(s)
      伊藤健太、松本泰治、高橋 潤、下川宏明
    • Organizer
      第20回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-19 – 2014-07-20
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Symposium: Update on coronary vasomotion

    • Author(s)
      Hiroaki Shimokawa
    • Organizer
      Rome Cardiology Forum 2012
    • Place of Presentation
      Rome, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] William Harvey Lecture: Importance of coronary vasomotion abnormalities –From bench to bedside-

    • Author(s)
      Shimokawa H.
    • Organizer
      European Society Congress 2014
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2014-08-30 – 2014-09-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Presentation] Enhanced adventitial vasa vasorum formation in patients with vasospastic angina -Assessment with optical frequency domain imaging-

    • Author(s)
      Nishimiya K, Matsumoto Y, Takahashi J, Kato T, Oyama K, Uzuka H, Odaka Y, Nihei T, Hao K, Tsuburaya R, Ito K, Shimokawa H.
    • Organizer
      American Heart Association (AHA) Scientific Sessions
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-24790732
  • [Presentation] Coronary spasm in 2012: Mechanisms and treatment.

    • Author(s)
      Hiroaki Shimokawa
    • Organizer
      Invited lecture at the Cardiac Society of Australia & New Zealand Meeting
    • Place of Presentation
      Adelaide, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] 低出力体外衝撃波治療は抗炎症作用を介して左室リモデリングを抑制する -ラット急性心筋梗塞モデルにおける検討-

    • Author(s)
      進藤智彦, 伊藤健太, 阿部譲, 尾形剛, 羽尾清貴, 西宮健介, 宮田敏, 川上和義, 下川宏明
    • Organizer
      第53回日本生体医工学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-24 – 2014-06-26
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Coronary spasm in 2012: Mechanisms and treatment.

    • Author(s)
      Hiroaki Shimokawa
    • Organizer
      Invited lecture at the Cardiac Society of Australia & New Zealand Meeting
    • Place of Presentation
      Adelaide, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390154
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲性血管新生療法

    • Author(s)
      藤健太、高橋 潤、松本泰治、円谷隆治、羽尾清貴、西宮健介、二瓶太郎、下川宏明
    • Organizer
      第55回日本脈管学会総会
    • Place of Presentation
      倉敷
    • Year and Date
      2014-10-30 – 2014-11-01
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Asian Lecture in Vascular Biology: Light and dark of reactive oxygen species for vascular function.

    • Author(s)
      Shimokawa H.
    • Organizer
      Pharmacology & Pgysiology International Scientific Congress 2014/Asian Society of Vascular Bilogy Meeting
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2014-08-22 – 2014-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Presentation] Prognostic Impact of Rho-kinase Activity in Circulating Leukocytes of Patients with Vasospastic Angina

    • Author(s)
      Taro Nihei, Jun Takahashi, Ryuji Tsuburaya, Kiyotaka Hao, Yuji Odaka, Kensuke Nishimiya, Yasuharu Matsumoto, Kenta Ito, Hiroaki Shimokawa
    • Organizer
      AHA Scientific Sessions 2014
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-25461038
  • [Presentation] Symposium: Update on coronary vasomotion

    • Author(s)
      Hiroaki Shimokawa
    • Organizer
      Rome Cardiology Forum 2012
    • Place of Presentation
      Rome, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659071
  • [Presentation] Symposium: Coronary vasospasm: what do we know and why is it important?: Pathogenesis of vasospastic angina.

    • Author(s)
      Shimokawa H.
    • Organizer
      2014 World Congress of Cardiology
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-05-04 – 2014-05-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670379
  • [Presentation] 心血管疾患に対する非侵襲性再生医療の開発:低出力体外衝撃波治療

    • Author(s)
      伊藤健太, 進藤智彦, 尾形剛, 畠中和明, 芹澤玄, 河村圭一郎, 高橋潤, 松本泰治, 圓谷隆治, 羽尾清貴, 西宮健介, 二瓶太郎, 小鷹悠二, 塙健一郎, 長谷部雄飛, 宇塚裕紀, 平野道基, 後藤均, 下川宏明
    • Organizer
      第53回日本生体医工学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-24 – 2014-06-26
    • Data Source
      KAKENHI-PROJECT-25461099
  • [Presentation] Enhanced adventitial vasa vasorum formation in patients with vasospastic angina - Assessment with optical frequency domain imaging-

    • Author(s)
      Nishimiya K, Matsumoto Y, Takahashi J, Kato T, Odaka Y, Nihei T, Hao K, Tsuburaya R, Ito K, Shimokawa H.
    • Organizer
      European Society Congress 2014
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2014-08-30 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-24790732
  • []

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  • 1.  TAKESHITA Akira (30038814)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  SUEISHI Katsuo (70108710)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  ICHKI Toshihiro (80311843)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  SATOH Kimio (80436120)
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  • 18.  ITO Kenta (50375086)
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  • 21.  MATSUDA Takehisa (60142189)
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  • 25.  SUMIMOTO Hideki (30179303)
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  • 26.  YANAGIHARA Nobuyuki (80140896)
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  • 27.  TAKEDA Morihiko (30375084)
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  • 28.  FUKUDA Koji (20375083)
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  • 29.  TSUBURAYA Ryuji (30599882)
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  • 30.  NISHIMIYA Kensuke (10734238)
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  • 31.  MATSUMOTO Yasuharu (90600528)
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  • 32.  TSUDA Hiroko (30180003)
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  • 33.  HARADA Mine (00019621)
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  • 34.  宮田 敏 (60360343)
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  • 35.  市來 俊弘
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  • 36.  UCHIDA Koji (40203533)
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  • 37.  MATSUMOTO Akio (60437308)
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  • 38.  URANO Yasuteru (20292956)
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  • 39.  ARIMOTO Hirokazu (60262789)
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  • 40.  ITOH Ken (10323289)
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  • 41.  UEHARA Takashi (00261321)
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  • 42.  KAMATA Hideaki (10233925)
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  • 43.  NISHIDA Motohiro (90342641)
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  • 44.  SASAGURI Yasuyuki (60140646)
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  • 45.  YADA Toyotaka (00210279)
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  • 46.  NAKAMOTO Hiroshi (10299183)
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  • 47.  MORITA Yoshitaka (50346441)
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  • 48.  OGASAWARA Yasuo (10152365)
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  • 49.  KAJIYA Fumihiko (70029114)
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  • 50.  WEI DAMING (20306434)
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  • 51.  ZHU Xin (70448645)
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  • 52.  SAKAI Motoki (50597094)
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  • 53.  Kawakami Kazuyoshi (10253973)
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  • 54.  URABE Yoshitoshi (10240904)
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  • 55.  NAKASHIMA Mikio (80159061)
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  • 56.  ITOU Takeo (70159888)
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  • 57.  SUZUKI Hikaru (80037548)
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  • 66.  NAGAI Ryozo (60207975)
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  • 114.  Odaka Yuji
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  • 115.  Nihei Taro
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  • 116.  Hao Kiyotaka
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  • 117.  Uzuka Hironori
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  • 118.  Ohyama Kazuma
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  • 119.  Amamizu Hirokazu
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  • 120.  Tuchiya Satoshi
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  • 121.  Kikuchi Yoku
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  • 123.  AL-MAMUN MD. ELI
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  • 124.  AL-MAMUN M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 125.  菊地 順裕
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    # of Collaborated Products: 1 results
  • 126.  建部 俊介
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    # of Collaborated Products: 2 results
  • 127.  BUDBAZAR Enkhjargal
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 128.  BUDBAZAR E.
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 129.  山本 沙織
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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