YAMAGUCHI TORU 山口徹

… Alternative Names

山口徹ヤマグチトオル

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Researcher Number	00239899
Affiliation (based on the past Project Information) *help	2013 – 2014: 島根大学, 医学部, 准教授 2007 – 2010: Shimane University, Department of Medicine, Associate Professor 2006: 島根大学, 医学部, 助教授 2002: 神戸大, 医学(系)研究科(研究院), 助手 2001: 神戸大学, 大学院・医学系研究科, 助手 1993: 神戸大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) / Endocrinology / Pathological medical chemistry Except Principal Investigator Endocrinology
Keywords	Principal Investigator 骨粗鬆症 / 糖尿病 / 骨芽細胞 / 骨髄間質細胞 / TGF-beta / 骨脆弱性 / 骨代謝回転 / 終末糖化産物 / 骨細胞 / Bone morphogenetic protein-2 … More / Rho-kinase / AMP Kinase / adiponectin / 動脈硬化 / osteoclcin / osteocalcin / IGF-I / 2型糖尿病 / メバロン酸経路 / 椎体骨折 / 老年医学 / オステオカルチン / アルカリファスターゼ / 石灰化 / カルシウム感知受容体 / 微絨毛 / メプリン / プロテアーゼ / 腎近位尿細管 / 腎臓 / 副甲状腺ホルモン … More Except Principal Investigator Wnt / Smart / Bone formation / Osteoblast / strontium / Stalin / Bisohosohonate / Parathyroid hormone / アポトーシス / TGFβ / グルココルチコイド / Lunt / Smad3 / Smad / ストロンチウム / smad / 骨形成 / 骨芽細胞 / スタチン / ビスフォスフォネート / 副甲状腺ホルモン Less

２型糖尿病における骨質劣化および骨折リスクに関する研究Principal Investigator
- Principal Investigator
  
  山口徹
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Shimane University
The pathogenesis of osteoporosis associated with diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI TORU
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Shimane University
Research for the elucidation of bone formation signals applied to the development of bone-forming agents
- Principal Investigator
  
  SUGIMOTO Toshitsugu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Shimane University
骨代謝・骨粗鬆症治療における骨芽細胞カルシウム感知受容体とその作動薬の役割の解明Principal Investigator
- Principal Investigator
  
  山口徹
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kobe University
ラット腎膜結合性副甲状腺ホルモン分解酵素の全一次構造の決定とその機能Principal Investigator
- Principal Investigator
  
  山口徹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University

All 2015 2014 2013 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 骨粗鬆症と生活習慣病(Annual Review 2011糖尿病・代謝・内分泌)(寺内康夫、伊藤裕、石橋俊編)2011
- Author(s)
  山口徹、杉本利嗣(分担執筆)
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590699
[Book] 生活習慣病骨折リスクに関する診療ガイド2011
- Author(s)
  分担執筆山口徹
- Total Pages
  11
- Publisher
  ライフサイエンス出版
- Data Source
  KAKENHI-PROJECT-20590699
[Book] Annual Review 2011糖尿病・代謝・内分泌2011
- Author(s)
  分担執筆山口徹、杉本利嗣
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590699
[Book] (第2章骨折リスクに関連する生活習慣病:1.糖尿病、3.メタボリック症候群;第4章生活習慣病の治療と骨折リスク:2.生活習慣病の治療による骨代謝の改善効果とその予測)(杉本利嗣編)2011
- Author(s)
  山口徹(分担執筆)
- Publisher
  生活習慣病骨折リスクに関する診療ガイドライフサイエンス出版
- Data Source
  KAKENHI-PROJECT-20590699
[Book] かかりつけ医でみる骨粗鬆症Q&A2010
- Author(s)
  分担執筆山口徹
- Total Pages
  4
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-20590699
[Book] Q.5糖尿病と骨粗鬆症発症に関連性はありますか?糖尿病が骨代謝に与える影響について教えて下さい。(かかりつけ医でみる骨粗鬆症Q&A)(西沢良記、中村利孝編)2010
- Author(s)
  山口徹(分担執筆)
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-20590699
[Book] Serum levels of Insulin-like growth factor-I, pentosidine, and adiponectin as markers for assessing bone condition in women with type 2 diabetes.2010
- Author(s)
  Kanazawa I, Yamaguchi T.
- Total Pages
  30
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-20590699
[Book] 各論:各種マーカーとその特徴C.その他のマーカー1.ucOCこれだけは知っておきたい骨代謝マーカー(西沢良記、三浦雅一、稲葉雅章編)2010
- Author(s)
  山口徹(分担執筆)
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590699
[Book] これだけは知っておきたい骨代謝マーカー2010
- Author(s)
  分担執筆山口徹
- Total Pages
  5
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590699
[Book] Serum levels of Insulin-like growth factor-I, pentosidine, and adiponectin as markers for assessing bone condition in women with type 2 diabetes.
- Author(s)
  Kanazawa I, Yamaguchi T
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Effects of high glucose and advanced glycation end products on the expressions of sclerostin and RANKL as well as apoptosis in osteocyte-like MLO-Y4-A2 cells.2015
- Author(s)
  Tanaka KI, Yamaguchi T, Kanazawa I, Sugimoto T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 451 Issue: 2 Pages: 1-5
- DOI
  10.1016/j.bbrc.2015.02.091
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460898
[Journal Article] Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion2014
- Author(s)
  Masakazu Notsu, Toru Yamaguchi, Kyoko Okazaki, Ken-ichiro Tanaka, Noriko Ogawa, Ippei Kanazawa, and Toshitsugu Sugimoto
- Journal Title
  
  Endocrinology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460898
[Journal Article] Involvement of the Osteoinductive Factors, Tmem119 and BMP-2, and the ER Stress Response PERK-eIF2α-ATF4 Pathway in the Commitment of Myoblastic into Osteoblastic Cells.2014
- Author(s)
  Tanaka KI, Kaji H, Yamaguchi T, Kanazawa I, Canaff L, Hendy GN, Sugimoto T.
- Journal Title
  
  Calcif. Tissue Int.
  
  Volume: 94 Pages: 454-464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460898
[Journal Article] Advanced glycation end products suppress osteoblastic differentiation of stromal cells by activating endoplasmic reticulum stress.2013
- Author(s)
  Tanaka K, Yamaguchi T, Kaji H, Kanazawa I, Sugimoto T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 438 Pages: 463-467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460898
[Journal Article] Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus.2011
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Kurioka S, Yano S, Sugimoto T.
- Journal Title
  
  Osteoporos.Int. 22
  
  Pages: 187-194
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus.2011
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Osteoporos.Int.
  
  Volume: 22 Pages: 187-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum osteocalcin level is positively associated with insulin sensitivity and secretion in patients with type 2 diabetes.2011
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Bone
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum Insulin-like growth factor-I is a maker far assessing the severity of vertebral fractures in postmenopausal women with type 2 diabetes mellitus.2011
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Osteoporos.Int.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Quantitative ultrasound and vertebral fractures in patients with type 2 diabetes.2011
- Author(s)
  Yamaguchi T, Yamamoto M, et al.
- Journal Title
  
  J.Bone.Miner.Metab.
  
  Volume: (印刷中)
- NAID
  10030894840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Baseline serum total adiponectin level is positively associated with changes in bone mineral density after 1 year treatment of type 2 diabetes.2010
- Author(s)
  Kanazawa I, Yamaguchi T, Sugimoto T.
- Journal Title
  
  Metabolism 59
  
  Pages: 1252-1256
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Baseline serum total adiponectin level is positively associated with changes in bone mineral density after 1 year treatment of type 2 diabetes.2010
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Metabolism
  
  Volume: 59 Pages: 1252-1256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Fasudil hydrochloride induces osteoblastic differentiation of stromal cell lines, C3H10T1/2 and ST2, via bone morphogenetic protein-2 expression.2010
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T.
- Journal Title
  
  Endocr.J. 57
  
  Pages: 415-421
- NAID
  10029584777
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Baseline atherosclerosis parameters could assess the risk of bone loss in type 2 diabetes mellitus during pioglitazone treatment.2010
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Osteoporos.Int.
  
  Volume: 21 Pages: 2013-2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Effects of treatment with risedronate and alfacalcidol on progression of atherosclerosis in postmenopausal women with type 2 diabetes mellitus accompanied with osteoporosis.2010
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Am J Med Sci.
  
  Volume: 339 Pages: 519-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Effects of treatment with risedronate and alfacalcidol on progression of atherosclerosis in postmenopausal women with type 2 diabetes mellitus accompanied with osteoporosis.2010
- Author(s)
  Kanazawa I, Yamaguchi T, Hayashi K, Takase H, Shimizu T, Sugimoto T.
- Journal Title
  
  Am J Med Sci. 339
  
  Pages: 519-524
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Baseline atherosclerosis parameters could assess the risk of bone loss in type 2 diabetes mellitus during pioglitazone treatment.2010
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Yamamoto M, Yamauchi M, Kurioka S, Sugimoto T.
- Journal Title
  
  Osteoporos.Int. 21
  
  Pages: 2013-2018
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Relationships between treatments with insulin and oral hypoglycemic agents versus the presence of vertebral fractures in type 2 diabetes mellitus.2010
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  J.Bone Miner.Metab.
  
  Volume: 28 Pages: 554-560
- NAID
  10027684019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Relationships between treatments with insulin and oral hypoglycemic agents versus the presence of vertebral fractures in type 2 diabetes mellitus.2010
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Sugimoto T.
- Journal Title
  
  J.Bone Miner.Metab. 28
  
  Pages: 554-60
- NAID
  10027684019
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Fasudil hydrochloride induces osteoblastic differentiation of stromal cell lines, C3H10T1/2 and ST2, via bone morphogenetic protein-2 expression.2010
- Author(s)
  Kanazawa I, Yamaguchi T, et al.
- Journal Title
  
  Endocr.J.
  
  Volume: 57 Pages: 415-421
- NAID
  10029584777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Relationships between dimethylarginine and the presence of vertebral fractures in type 2 diabetes mellitus.2010
- Author(s)
  Kanazawa I, Yano S, Yamaguchi T, Notsu Y, Nabika T, Sugimoto T.
- Journal Title
  
  Clin.Endocrinol. 73
  
  Pages: 463-468
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Inhibition of the mevalonate pathway rescues the dexamethasone-induced suppression of the mineralization in osteoblasts via enhancing bone morphogenetic protein-2 signal.2009
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Hayashi K, Yamauchi M, Sugimoto T.
- Journal Title
  
  Horm.Metab.Res. 41
  
  Pages: 612-616
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus.2009
- Author(s)
  Kanazawa I,Yamaguchi T, Yamamoto M, Yamauchi M, Kurioka S, Yano S, Sugimoto T.
- Journal Title
  
  J.Clin.Endocrinol.Metab. 94
  
  Pages: 45-49
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Relationships between serum adiponectin levels versus bone mineral density, bone metabolic markers, and ertebral fractures in type 2 diabetes mellitus.2009
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  Eur.J.Endocrinol. 160
  
  Pages: 265-273
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Low serum level of the endogenous secretory receptor for advanced glycation end-products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes.2009
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Sugimoto T.
- Journal Title
  
  Diabetes Care 32
  
  Pages: 2263-2268
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Adiponectin is associated with changes in bone markers during glycemic control in type 2 diabetes mellitus.2009
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  J.Clin.Endocrinol.Metab. 94
  
  Pages: 3031-3037
- NAID
  40016591700
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum osteocalcin/bone specific alkaline phosphatase ratio is a predictor for the presence of vertebral fractures in men with type 2 diabetes.2009
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  Calcif.Tissue Int. 85
  
  Pages: 228-234
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes.2009
- Author(s)
  Yamaguchi T
- Journal Title
  
  Bone 45
  
  Pages: 174-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Diabetic patients have an increased risk of vertebral fractures independent of bone mineral density or diabetic complications.2009
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Kaji H, Sugimoto T.
- Journal Title
  
  J.Bone Miner.Res. 24
  
  Pages: 702-709
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes.2009
- Author(s)
  Yamaguchi T, Kanazawa I, Yamamoto M, Kurioka S, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  Bone 45
  
  Pages: 174-179
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Rosuvastatin increased serum osteocalcin levels independent of its serum cholesterol- lowering effect in patients with type 2 diabetes and hypercholesterolemia.2009
- Author(s)
  Kanazawa I, Yamaguchi T, Yamauchi M, Sugimoto T.
- Journal Title
  
  Intern.Med. 48
  
  Pages: 1869-1873
- NAID
  130000122199
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Activation of AMP-kinase and inhibition of Rho-kinase induce the mineralization of osteoblastic MC3T3-E1 cells through endothelial NOS and BMP-2 expression.2009
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T.
- Journal Title
  
  Am.J.Physiol.Endocrinol.Metab. 296
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum DHEA-S level is associated with the presence of atherosclerosis in postmenopausal women with type 2 iabetes mellitus.2008
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Kurioka S, Yano S, Sugimoto T.
- Journal Title
  
  Endocr.J. 55
  
  Pages: 667-676
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes.2008
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  J.Clin.Endocrinol.Metab. 93
  
  Pages: 1013-1019
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Metformin enhances the differentiation and mineralization of osteoblastic MC3T3-E1 cells via AMP kinase activation as well as eNOS and BMP-2 expression.2008
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 375
  
  Pages: 414-419
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Combination of obesity with hyperglycemia is a risk factor for the presence of vertebral fractures in type 2 diabetic men.2008
- Author(s)
  Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  Calcif.Tissue Int. 83
  
  Pages: 324-331
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] The combination of high glucose and advanced glycation end-products (AGEs) unhibit the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs2007
- Author(s)
  Ogawa, N., Yamaguchi, N., Yano, S., Yamauchi, M., Yamamoto, M., Sugimoto, T
- Journal Title
  
  Horm Metab Res 39
  
  Pages: 871-875
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Journal Article] Serum calcium is positively correlated with fasting plasma glucose and insulin resistance, independent of parathyroid hormone, in male patients with type 2 diabetes mellitus.
- Author(s)
  Yamaguchi T, Kanazawa I, Takaoka S, Sugimoto T.
- Journal Title
  
  Metabolism in press
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Quantitative ultrasound and vertebral fractures in patients with type 2 diabetes.
- Author(s)
  Yamaguchi T, Yamamoto M, Kanazawa I, Yamauchi M, Yano S, Tanaka N, Nitta E, Fukuma A, Uno S, Sho-no T, Sugimoto T.
- Journal Title
  
  J.Bone.Miner.Metab. in press
- NAID
  10030894840
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Effects of metformin and pioglitazone on serum pentosidine levels in type 2 diabetes mellitus.
- Author(s)
  Kanazawa I, Yamamoto M, Yamaguchi T, Sugimoto T.
- Journal Title
  
  Exp.Clin.Endocrinol.Diab in press
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients type 2 diabetes mellitus.
- Author(s)
  Kanazawa I, Yano S, Notsu Y, Yamaguchi T,Nabika T, Sugimoto T.
- Journal Title
  
  Clin.Endocrinol.Epub ahead of print
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Serum osteocalcin level is positively associated with insulin sensitivity and secretion in patients with type 2 diabetes.
- Author(s)
  Kanazawa I,Yamaguchi T, Tada Y, Yamauchi M, Yano S, Sugimoto T.
- Journal Title
  
  Bone in press
- Data Source
  KAKENHI-PROJECT-20590699
[Journal Article] Adiponectin and AMP kinase activator stimulates proliferation, differtentiation and mineralization of osteonlastic MC3T3-E1 cells
- Author(s)
  Kanazawa, I., Yamaguchi, T., Yano, S., Yamauchi, M., Yamamoto, M., Sugimolto, T
- Journal Title
  
  BMC Cell Biol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Journal Article] Serum Insulin-like growth factor-I is a maker for assessing the severity of vertebral fractures in ostmenopausal women with type 2 diabetes mellitus.
- Author(s)
  Kanazawa I, Yamaguchi T, Sugimoto T.
- Journal Title
  
  Osteoporos.Int. in press
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 日韓合同シンポジウムInterplay between osteoporosis and diabetes mellitus.2010
- Author(s)
  山口徹
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] パネルディスカッション:骨粗鬆症診療の動向と今後生活習慣病を合併した骨粗鬆症治療戦略2010
- Author(s)
  山口徹
- Organizer
  第6回SERM学術研究会学術集会
- Place of Presentation
  東京都・東京ステーションコンファレンス(招待講演)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] シンポジウム:生活習慣病と骨粗鬆症:糖尿病・メタボリック症候群と骨折リスク2010
- Author(s)
  山口徹、杉本利嗣
- Organizer
  第12回日本骨粗鬆症学会
- Place of Presentation
  大阪市・大阪国際会議場(招待講演)
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Quantitative ultrasound of the calcaneus is not useful for assessing the risk of vertebral fractures in patients with tune 2 diabetes.2010
- Author(s)
  Yamaguchi T, Yamamoto M, et al.
- Organizer
  IOF Regionals Singapore '10 1st Asia-Pacific Osteoporosis Meeting
- Place of Presentation
  Singapore・Raffle's City Convention Center
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Serum level of an endogenous secretary receptor for advanced glycation end-products (esRAGE) is useful for assessing the risk of prevalent vertebral fractures independent of BMD in patients with type 2 diabetes.2010
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Decreased PTH secretion is associated with low bone formation and vertebral fracture risk in postmenopausal women with type 2 diabetes.2010
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Nawata K, Sugimoto T
- Organizer
  The 32th American Society for Bone and Mineral Research
- Place of Presentation
  Toronto, Ontario, Canada
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 日韓合同シンポジウム Interplay between osteoporosis and diabetes mellitus.2010
- Author(s)
  Yamaguchi T
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京都・京王プリンスホテル(招待講演)
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 生活習慣病と骨粗鬆症:糖尿病・メタボリック症候群と骨折リスク2010
- Author(s)
  山口徹、杉本利嗣シンポジウム
- Organizer
  第12回日本骨粗鬆症学会
- Place of Presentation
  大阪
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Quantitative ultrasound of the calcaneus is not useful for assessing the risk of vertebral fractures in patients with type 2 diabetes.2010
- Author(s)
  Yamaguchi T, Yamamoto M, Kanazawa I, Yamauchi M, Kurioka S, Yano S, Sugimoto T
- Organizer
  IOF Regionals Singapore' 10 1st Asia-Pacific Osteoporosis Meeting
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 骨粗鬆症診療の動向と今後生活習慣病を合併した骨粗鬆症治療戦略2010
- Author(s)
  山口徹パネルディスカッション
- Organizer
  第6回SERM学術研究会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] シンポジウム:骨芽細胞におけるAMP-kinaseおよびメバロン酸経路の役割2009
- Author(s)
  山口徹
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 糖・脂質代謝と骨2009
- Author(s)
  山口徹、杉本利嗣ミニシンポジウム
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] ミニシンポジウム:糖・脂質代謝と骨2009
- Author(s)
  山口徹
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in patients with type 2 diabetes.2009
- Author(s)
  Yamaguchi T, Kanazawa I, Yamamoto M, Yamauchi M, Kurioka S, Yano S, Sugimoto T
- Organizer
  2nd Joint Meeting of the International Bone & Mineral Society and the Australian and New Zealand Bone and Mineral Society.
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Serum Level of an Endogenous Secretory Receptor for Advanced Glycation End-products (esRAGE) Is Useful for Assessing the Risk of Prevalent Vertebral Fractures Independent of BMD in Patients with Type 2 Diabetes.2009
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T
- Organizer
  The 31th American Society for Bone and Mineral Research
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 骨芽細胞におけるAMP-kinaseおよびメバロン酸経路の役割2009
- Author(s)
  山口徹、金沢一平、林公美、矢野彰三、山内美香、山本昌弘、杉本利嗣シンポジウム
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes.2009
- Author(s)
  Yamaguchi T, Kanazawa I, Yamamoto M, Yamauchi M, Yano S, Sugimoto T
- Organizer
  The 31th American Society for Bone and Mineral Research
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Undercarboxylated osteocalcin/osteocalcin ratio is negatively associated with hyperglycemic conditions, but not with the presence of vertebral fractures, in patients with type 2 diabetes.2009
- Author(s)
  Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T
- Organizer
  2nd Joint Meeting of the International Bone & Mineral Society and the Australian and New Zealand Bone and Mineral Society.
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] メタボリック症候群が骨密度、椎体骨折に与える影響の検討2008
- Author(s)
  山口徹, ほか
- Organizer
  第10回日本骨粗鬆症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] BMP/wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH : Potential therapeutic targets for glucocorticoid -induced osteoporosis.2008
- Author(s)
  Yamaguchi T, et al.
- Organizer
  The 30^<th> American Society for Bone and Mineral Research
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Inhibition of the mevalonate pathway rescues the dexamethasoneinducedsuppression of the mineralization of osteoblastic ells.2008
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Hayashi K, Yamauchi M, Sugimoto
- Organizer
  The 30^<th> American Society for Bone and Mineral Research, Montreal
- Place of Presentation
  Canada
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] 骨芽細胞様細胞MC3T3-E1においてDexamethasoneによるBMP/Wnt antagonists, inhibitorの発現増強およびRunx2の低下、石灰化抑制はAlendronateやParathyroid hormone 添加により解除される2008
- Author(s)
  山口徹, ほか
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590699
[Presentation] Glucocorticoid suppresses the differentiation of osteoblasts by enhancing the expression of BMP antagonists, follistatin and danm and pretreatment with alendronate and PTH abolish this process2007
- Author(s)
  Hayashi, K., Yamaguchi, T., Yano, S., Yamauchi, M., Yamamoito, M., The, Sugimoto, T
- Organizer
  The American Society for Bone Mineral Research
- Place of Presentation
  Hawaii USA
- Year and Date
  2007-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Presentation] AMP kinase activator (AICAR) and Rho-kinasse inhibitor (hydroxyfasudil) induce the differentiation and mineralization of osteoblastic MC3T3-E1 cells via inhibiting the mavalonate pathway and enhancing BMP-2 expression2007
- Author(s)
  Kanazawa, I., Yamaguchi, T., Yano, S., yamauchi, M., Yamamoto, M., Sugimoto, T
- Organizer
  The American Society for Bone Mineral Research
- Place of Presentation
  Hawaii USA
- Year and Date
  2007-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Presentation] Adiponectin stimulates the proliferation, differentiation and mineralization of osteoblastic MC3T3-E1 cells via the adiponectin receptor typel and AMMP signaling pathway2006
- Author(s)
  Kanazawa, I., Yamaguchi, T., Yano, S., Yamauchi, M., Yamamoto, M., Sugimoto, T
- Organizer
  3rd International Osteoporosis Foundation Asia-Pacific Regional Conference onn Osteoporosis & 16th Annual Meeting of the Australian and New Zealand Bone and Mineral Society
- Place of Presentation
  Port Douglas, Australia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Presentation] AGE2,3が骨細胞のsclerostin、RANKL発現及びアポトーシスに及ぼす影響
- Author(s)
  田中　賢一郎、山口　徹、金沢　一平　、杉本　利嗣
- Organizer
  第３２回日本骨代謝学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25460898

1. SUGIMOTO Toshitsugu (00226458)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. YAMAMOTO Masahiro (50346392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
3. KANAZAWA Ippei (50452553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 39 results
4. YANO Shozo (80403450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. YAMAUCHI Mika (40379681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

YAMAGUCHI TORU 山口 徹

山口 徹 ヤマグチ トオル

Research Projects

Research Products

Co-Researchers

２型糖尿病における骨質劣化および骨折リスクに関する研究Principal Investigator

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The pathogenesis of osteoporosis associated with diabetes mellitusPrincipal Investigator

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Research for the elucidation of bone formation signals applied to the development of bone-forming agents

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骨代謝・骨粗鬆症治療における骨芽細胞カルシウム感知受容体とその作動薬の役割の解明Principal Investigator

Principal Investigator

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ラット腎膜結合性副甲状腺ホルモン分解酵素の全一次構造の決定とその機能Principal Investigator

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[Book] 骨粗鬆症と生活習慣病(Annual Review 2011糖尿病・代謝・内分泌)(寺内康夫、伊藤裕、石橋俊編)2011

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[Book] 生活習慣病骨折リスクに関する診療ガイド2011

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[Book] Annual Review 2011糖尿病・代謝・内分泌2011

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[Book] (第2章骨折リスクに関連する生活習慣病:1.糖尿病、3.メタボリック症候群;第4章生活習慣病の治療と骨折リスク:2.生活習慣病の治療による骨代謝の改善効果とその予測)(杉本利嗣編)2011

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[Book] かかりつけ医でみる骨粗鬆症Q&A2010

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[Book] Q.5糖尿病と骨粗鬆症発症に関連性はありますか?糖尿病が骨代謝に与える影響について教えて下さい。(かかりつけ医でみる骨粗鬆症Q&A)(西沢良記、中村利孝編)2010

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[Book] Serum levels of Insulin-like growth factor-I, pentosidine, and adiponectin as markers for assessing bone condition in women with type 2 diabetes.2010

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[Book] 各論:各種マーカーとその特徴C.その他のマーカー1.ucOCこれだけは知っておきたい骨代謝マーカー(西沢良記、三浦雅一、稲葉雅章編)2010

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[Book] これだけは知っておきたい骨代謝マーカー2010

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[Book] Serum levels of Insulin-like growth factor-I, pentosidine, and adiponectin as markers for assessing bone condition in women with type 2 diabetes.

Author(s)

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YAMAGUCHI TORU 山口徹

山口徹ヤマグチトオル