INAZU Tetsuya 稲津哲也

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Inazu Tetsuya 稲津哲也

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Researcher Number	00242587
Other IDs
Affiliation (Current)	2025: 立命館大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 立命館大学, 薬学部, 教授 1999: Fukui Medical University, Department of Biochemistry, Assistant Professor, 医学部, 助手 1993 – 1997: 福井医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / General medical chemistry / Pathological medical chemistry Except Principal Investigator Endocrinology / General medical chemistry / Pathological medical chemistry
Keywords	Principal Investigator pleckstrin homology / CDKL5 / protein kinase C / チロシンキナーゼ / 機能異常症 / CDKL5欠損症 / 精神神経発達 / 希少疾患 / 病態解析 / ノックインマウス … More / 機能異常 / 漢方薬 / レット症候群 / 細胞内情報伝達 / 神経分化 / cdkl5ノックアウトマウス / Cdkl5ノックアウトマウス / 神経分化誘導作用 / 一味抜き成分 / 抑肝散 / genome DNA cloning / pleckstrin cDNA cloning / リン脂質 / ゲノムDNAクローニング / pleckstrin cDNAクローニング / 会合 / cDNA / 血球系 / syk … More Except Principal Investigator Syk / Lyn / 転写因子 / Shc / チロシンキナーゼ / inducible gene / transcription factor / ゴナドトロピン / トロンビン / p72syk / PLCγ / PI3キナーゼ / ピルビン酸キナーゼ遺伝子 / human homologue / ovary / 遺伝子診断 / 腫瘍 / ホルモン誘導性 / ヒトホモローグ / 卵巣 / gene expression / gonadotropin / 卵胞発育 / 卵巣顆粒膜細胞 / 遺伝子発現 / 誘導性 / Homeobox gene / Hepatocytes / Transcription factor / Pyruvate kinase gene / Transcriptional regulation / ホメオボックス遺伝子 / 肝細胞 / 転写制御 / Thrombin / PI 3 kinase / Interleukin2 / PLCgamma / Tyrosine kinase / 活性化機構 / コンカナバリンA / トロンボキサンA_2 / インターロイキン2 / mast cell / FcgammaRIIIA / IgE receptor / B cell receptor / DT-40 cell / Protein-tyrosine kinase / 血小板 / B細胞受容体 / IgE受容体 / GAP / RBL-2H3細胞 / DT40細胞 / SH2 / 選択的スプライシング / HNF4 / NF1ファミリー / PI3-kinase / GTP結合蛋白質 Less

Fundamental research to propose a novel disease of CDKL5 dysfunctionPrincipal Investigator
- Principal Investigator
  
  稲津哲也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Ritsumeikan University
Creation of therapeutic agent for Rett syndrome (CDKL5 deficiency disorder) using Kampo medicinePrincipal Investigator
- Principal Investigator
  
  Inazu Tetsuya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Ritsumeikan University
Research on the role of a new hormone-inducible transcription factor GIOT for the ovarian function.
- Principal Investigator
  
  MIYAMOTO Kaoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fukui Medical University
  Gunma University
Applied research for the development of gene diagnosis of ovarian dysfunction using a novel ovarian transcription factor GIOT.
- Principal Investigator
  
  MIYAMOTO Kaoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fukui Medical University
  Gunma University
Regulation of transcription and splicing of pyruvate kinase isozyme genes
- Principal Investigator
  
  NOGUCHI Tamio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
  福井医科大学
ピルビン酸キナーゼアイソザイム遺伝子の転写とスプライシングを制御する因子
- Principal Investigator
  
  NOGUCHI Tamio
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  福井医科大学
Functional and physiological analysis of plechstrin homology domain structurePrincipal Investigator
- Principal Investigator
  
  INAZU Tetsuya
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Fukui Medical School
蛋白質チロシンキナーゼp72^<Syk>を介する細胞内情報伝達とG蛋白質
- Principal Investigator
  
  YAMAMURA Hirohei
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  福井医科大学
プレクストリン(血小板47KD蛋白)構造を有する遺伝子の同定とその機能Principal Investigator
- Principal Investigator
  
  稲津哲也
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  福井医科大学
非受容体型蛋白質チロシンキナーゼp72^<syk>のヒト遺伝子並びに関連遺伝子の同定Principal Investigator
- Principal Investigator
  
  稲津哲也
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  福井医科大学
Physiological role of protein-tyrosine kinase p72^<syk>
- Principal Investigator
  
  YAMAMURA Hirohei
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kobe University
  福井医科大学
Physiological function of non-receptor type protein-tyrosine kinase p72^<syk>
- Principal Investigator
  
  YAMAMURA Hirohei
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KOBE UNIBERSITY
  福井医科大学

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Role of plant homeodomain finger protein 8 in P19 embryonic carcinoma cells revealed by genome editing and specific inhibitor2024
- Author(s)
  Doi Shusuke、Suzuki Takayoshi、Soeda Shuhei、Miyata Naoki、Inazu Tetsuya
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 38 Pages: 101670-101670
- DOI
  10.1016/j.bbrep.2024.101670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07235, KAKENHI-PROJECT-21H04795
[Journal Article] Total colectomy for poorly controlled hypokalemia due to Gitelman syndrome2023
- Author(s)
  Tetsuya Kawahara, Tetsuya Inazu, Shingo Ishida
- Journal Title
  
  BMJ Case Reports
  
  Volume: 16(2):e252916. Issue: 2 Pages: e252916-e252916
- DOI
  10.1136/bcr-2022-252916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Comprehensive in silico functional prediction analysis of CDKL5 by single amino acid substitution in the catalytic domain2022
- Author(s)
  Yuri Yoshimura , Atsushi Morii, Yuuki Fujino, Marina Nagase, Arisa Kitano, Shiho Ueno, Kyoka Takeuchi, Riko Yamashita, Tetsuya Inazu
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23(20) Issue: 20 Pages: 12281-12281
- DOI
  10.3390/ijms232012281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population2022
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Tetsuya Inazu, Fumiyoshi Kasagi, Chie Kawahara, Yosuke Okada, Yoshiya Tanaka
- Journal Title
  
  BMJ
  
  Volume: 377 Pages: e066222-e066222
- DOI
  10.1136/bmj-2021-066222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] HDAC8 is implicated in embryoid body formation via canonical Hedgehog signaling and regulates neuronal differentiation2022
- Author(s)
  Atsushi Morii, Tetsuya Inazu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 629 Pages: 78-85
- DOI
  10.1016/j.bbrc.2022.08.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Zinc finger protein 483 (ZNF483) regulates neuronal differentiation and methyl-CpG-binding protein 2 (MeCP2) intracellular localization2021
- Author(s)
  Yasui Gen、Katayama Syouichi、Kubota Yukihiko、Takatsuka Hisashi、Ito Masahiro、Inazu Tetsuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 568 Pages: 68-75
- DOI
  10.1016/j.bbrc.2021.06.066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264, KAKENHI-PROJECT-20K15751
[Journal Article] Establishment of a Simple Method for Inducing Neuronal Differentiation of P19 EC Cells without Embryoid Body Formation and Analysis of the Role of Histone Deacetylase 8 Activity in This Differentiation2020
- Author(s)
  Atsushi Morii, Syouichi Katayama, Tetsuya Inazu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 7 Pages: 1096-1103
- DOI
  10.1248/bpb.b20-00091
- NAID
  130007867918
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] Cyclin-dependent kinase-like 5 (CDKL5): Possible cellular signaling targets and involvement in CDKL5 deficiency disorder2020
- Author(s)
  Syouichi Katayama, Noriyuki Sueyoshi, Tetsuya Inazu, Isamu Kameshita
- Journal Title
  
  Neural Plasticity
  
  Volume: volume 2020 Pages: 6970190-6970190
- DOI
  10.1155/2020/6970190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264, KAKENHI-PROJECT-20K15751
[Journal Article] Yokukansan, a Kampo medicine, enhances the level of neuronal lineage markers in differentiated P19 embryonic carcinoma cells2019
- Author(s)
  Fukui Makoto、Katayama Syouichi、Ikeya Yukinobu、Inazu Tetsuya
- Journal Title
  
  Heliyon
  
  Volume: 5 Issue: 10 Pages: e02662-e02662
- DOI
  10.1016/j.heliyon.2019.e02662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Journal Article] In Silico Study of Rett Syndrome Treatment-Related Genes, MECP2, CDKL5, and FOXG1, by Evolutionary Classification and Disordered Region Assessment2019
- Author(s)
  Fahmi Muhamad、Yasui Gen、Seki Kaito、Katayama Syouichi、Kaneko-Kawano Takako、Inazu Tetsuya、Kubota Yukihiko、Ito Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 22 Pages: 5593-5593
- DOI
  10.3390/ijms20225593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Efficacy of active vitamin D treatment to prevent sarcopenia in adults with prediabetes: randomized controlled trial2024
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Naoki Tominaga, Yoshiya Tanaka, Tetsuya Inazu
- Organizer
  The 21st International Congress of Endocrinology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07235
[Presentation] Active Vitamin D Treatment and Prevention of Sarcopenia in Adults with Prediabetes2023
- Author(s)
  Tetsuya Kawahara, Gen Suzuki, Shoichi Mizuno, Naoki Tominaga, Hideki Yamada, Mikio Toda, Nagahiro Toyama, Chie Kawahara, Yosuke Okada, Yoshiya Tanaka, Tetsuya Inazu
- Organizer
  9th Asian Conference for Frailty and Sarcopenia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07235
[Presentation] P19細胞における神経分化過程でのhistone deacetylase 8の機能解析2023
- Author(s)
  森井篤、稲津哲也
- Organizer
  日本薬学143年会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] CDKL5 ノックインマウスの行動解析2022
- Author(s)
  武内杏夏、鎌田雅之、稲津哲也
- Organizer
  国際稀少疾患シンポジウム　2022 at Ritsumeikan
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] レット症候群原因遺伝子CDKL5の触媒部位内１アミノ酸置換による網羅的in silico 機能予測解析と臨床報告例との相関2022
- Author(s)
  吉村優里、藤野優希、森井篤、武内杏夏、北野有砂、山下莉子、上野支帆、Muhamad Fahmi、伊藤將弘、稲津哲也
- Organizer
  日本薬学会　第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] レット症候群原因遺伝子 CDKL5 の触媒部位内1アミノ酸置換による網羅的 in silico 機能予測解析2022
- Author(s)
  吉村優里、森井篤、藤野優希、武内杏夏、北野有砂、山下莉子、上野支帆、稲津哲也
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] レット症候群原因遺伝子 CDKL5 の触媒部位内1アミノ酸置換による網羅的 in silico 機能予測解析2022
- Author(s)
  吉村優里、森井篤、藤野優希、武内杏夏、北野有砂、山下莉子、上野支帆、稲津哲也
- Organizer
  国際稀少疾患シンポジウム 2022 at Ritsumeikan
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] HDAC8の欠損は神経分化不全を導く2020
- Author(s)
  森井篤、片山将一、稲津哲也
- Organizer
  第70回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Phf8ノックアウトP19胚性腫瘍細胞株の樹立とその解析2020
- Author(s)
  土井秀介、森井篤、片山将一、稲津哲也
- Organizer
  第43回　日本分子生物学会年会　2020/12/3
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Yokukansan, a Japanese traditional medicine, enhances the level of neuronal lineage markers in differentiated wild and cdkl5 knockout P19 embryonic carcinoma cells2020
- Author(s)
  Tetsuya Inazu, Makoto Fukui, Sakino Iwata, Yukinobu Ikeya, Syouichi Katayama
- Organizer
  CDKL5 Forum 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] P19EC細胞における「一味抜き抑肝散」の神経分化への効果検討2020
- Author(s)
  岩田彩生乃、片山将一、池谷幸信、稲津哲也
- Organizer
  第70回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] P19細胞における神経分化過程でのHDAC8の機能解析2020
- Author(s)
  森井篤、片山将一、稲津哲也
- Organizer
  日本薬学会　第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] ドッキングシュミレーションによるCyclin-dependent kinase-like 5の基質タンパク質同定2020
- Author(s)
  高原　亜邪、片山将一、河野貴子、稲津哲也、菊地武司
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Phf8ノックアウトP19胚性腫瘍細胞株を用いたPHF8の機能解析2020
- Author(s)
  土井秀介、森井篤、片山将一、稲津哲也
- Organizer
  第70回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Expression analysis of Rett syndrome-related genetic factors, e.g. CDKL5, in HDAC8 knockout P19 cells2019
- Author(s)
  Atsushi Morii, Mako Saito, Syouichi Katayama, Tetsuya Inazu
- Organizer
  CDKL5 Workshop in Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Hdac8 KO P19細胞におけるRett症候群関連因子の発現変動とその解析2019
- Author(s)
  森井篤、片山将一、斎藤磨子、土井秀介、稲津哲也
- Organizer
  第69回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] PDGFとCDKL5はNeuro2a細胞の神経突起伸長を制御する2019
- Author(s)
  南光貴裕、坂口逸紀、土井秀介、森井篤、片山将一、稲津哲也
- Organizer
  第69回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] A novel CDKL5 mutation in an atypical Rett syndrome patient and development a convenient method for detecting CDKL5 activity2019
- Author(s)
  Syouichi Katayama, Tetsuya Inazu
- Organizer
  CDKL5 Workshop in Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264
[Presentation] Yokukansan, a Kampo medicine, enhances the level of neuronal lineage markers in differentiated P19 embryonic carcinoma cells2019
- Author(s)
  Syouichi Katayama, Makoto Fukui, Sayaka Suzuki , Yukinobu Ikeya , Tetsuya Inazu
- Organizer
  CDKL5 Workshop in Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08264

1. MARUYAMA Shingo (90262633)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. YAMAMURA Hirohei (90030882)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YANAGI Shigeru (60252003)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NOGUCHI Tamio (70135721)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMADA Kazuya (20263238)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TANIGUCHI Takanobu (60217130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIYAMOTO Kaoru (30125877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 峯岸敬 (00209842)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 保坂公平 (70108992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YAMAMOTO Tadashi (40134621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SADA Kiyonao (10273765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MINAMI Yasuhiro (70229772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 竹内郁登 (70262623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中輝幸 (10246647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 片山将一 (60779049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
16. 池田宏輝 (70819911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KUROSAKI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KINET Jean-pierre

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TOMOHIRO Kur

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

INAZU Tetsuya 稲津 哲也

Inazu Tetsuya 稲津 哲也

Research Projects

Research Products

Co-Researchers

Fundamental research to propose a novel disease of CDKL5 dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of therapeutic agent for Rett syndrome (CDKL5 deficiency disorder) using Kampo medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the role of a new hormone-inducible transcription factor GIOT for the ovarian function.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Applied research for the development of gene diagnosis of ovarian dysfunction using a novel ovarian transcription factor GIOT.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of transcription and splicing of pyruvate kinase isozyme genes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ピルビン酸キナーゼアイソザイム遺伝子の転写とスプライシングを制御する因子

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional and physiological analysis of plechstrin homology domain structurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

蛋白質チロシンキナーゼp72^<Syk>を介する細胞内情報伝達とG蛋白質

Principal Investigator

Project Period (FY)

Research Category

Research Institution

プレクストリン(血小板47KD蛋白)構造を有する遺伝子の同定とその機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

非受容体型蛋白質チロシンキナーゼp72^<syk>のヒト遺伝子並びに関連遺伝子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological role of protein-tyrosine kinase p72^<syk>

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Physiological function of non-receptor type protein-tyrosine kinase p72^<syk>

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Role of plant homeodomain finger protein 8 in P19 embryonic carcinoma cells revealed by genome editing and specific inhibitor2024

Author(s)

Journal Title

DOI

Data Source

INAZU Tetsuya 稲津哲也

Inazu Tetsuya 稲津哲也

[Presentation] レット症候群原因遺伝子CDKL5の触媒部位内１アミノ酸置換による網羅的in silico 機能予測解析と臨床報告例との相関2022