HASHIMOTO Shuichi 橋本修一

Researcher Number	00243931
Affiliation *help	2014 – 2015 : 福岡歯科大学, 歯学部, 教授 2013 : 熊本大学, 大学院生命科学研究部(医), 准教授 2012 : 熊本大学, 大学院生命科学研究部機能病理学分野, 准教授 2011 : Kumamoto University, 准教授 2011 : 熊本大学, 生命科学研究部, 准教授 … More
Research Field	Principal Investigator Human pathology / Human pathology Except Principal Investigator Human pathology / Experimental pathology / Respiratory organ internal medicine / Human pathology / Experimental pathology
Keywords	Principal Investigator 肺癌 / 予後因子 / Lgr6 / SP-B / 発生母細胞 / クララ細胞 / SP-A / 幹細胞 / 肺腺癌 / Wnt … More Except Principal Investigator 血管新生 / 遺伝子治療 / p53 / VEGF / 遺伝子導入 / SP-A / CC10 / Gene Transfer / Endothelial Cell / 血管内皮細胞 / Angiogenesis / 血管リモデリング / Piperonylbutoxide (PIP) / マイクロディセクション / Vascular Remodeling / Lung tumor / RAT / atherosclerosis / Gene Therapy / 転写因子 / NO / 血栓症 / MCP-1 / 肺腺がん / 肺腺癌 / 動脈硬化 / Sev / PCNA / proSP-C / FGF-2 / N-Nitrosodiethylamine (DEN) / angiogenesis / N-nitrosodiethylamine / Sevベクター / TIMP-2 / Airway epithelium / 導入効率 / apoptosis / Ki-67 (MIB-1) / Stem Cell / Sox9 / HVJ・liposome法 / Sox2 / 病理標本 / 培養肺腫瘍細胞 / gene transfer vector / Decoy / 異型腺腫様過形成(AAH) / Microdissection / 発癌 / 肺線がん / 肝 / Stem cell / Lung Cancer / 末梢型肺腺がん / HVJ-catinic liposome / アンチセンス / HVJ-lipsome method / 浸潤能 / ラット / エンドペプチダーゼ / 遺伝子導入ベクター / Differentiation / Transcription Factor / Epithelium / beta-catenin / 基質膜抗原 / vascular remodeling / 一酸化窒素 / レーザーマイクロディセクション / 肺扁平上皮癌 / Notch / アポトーシス / cross-talk sianal / Liposome / 血管新生病 / HVJ-liposome / 異型線腫様過形成 / シグナル伝達 / II型肺胞上皮細胞 / デコイ / プロテオミクス / 血管 / リポソーム / Cancer / MMP / Lung / プロテオーム解析 / 肺腫瘍 / p63 / Antisense / デコイオリゴ / PTCA / Atypical Adenomatous Hyperplasia (AAH) / gene therapy / EP-24.16 / Ki-67(MIB-1) / TGFβ^1 / PCR-SSCP / サーファクタント・アポ蛋白 / 転移 / 遺伝子解析 / 肺異型腺腫様過形成 Less

肺癌におけるR-spondin-Lgr6シグナル系の発現・機能解析Principal InvestigatorOngoing
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Fukuoka Dental College
Analysis of beta-Catenin/Sox2/p63 Signal Pathway in Lung Epithelial Differentiation and TumorigenesisPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Shuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kumamoto University
肺癌におけるFGFs、FGFRsおよびSproutysの発現・機能解析Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
病理標本におけるタンパク質発現動態からの分子病態解析の試み
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic process.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
ヒト肺腺癌と前癌病変(AAH)における発癌関与遺伝子のDNAマイクロアレイ解析Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
ディファレンシャルディスプレイを利用した病理標本の分子病態学的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Patho-physiological studies on cellular interaction in vascular injury and vascular remodeling
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
Trial research for practical use of the reagent for gene expression control by Decoy oligo nucleotide.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
腫瘍増殖におけるメタロエンドペプチダーゼEP-24.16の分子病態学的解析
- Principal Investigator
  
  中川和憲
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Molecular pathobiological Study on Endothelial Function Ocurring during Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
Gene Abberation Analysis in Precancerous Lesion of the Lung Adenocarcinoma by Laser Microdissection SystemPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Shuichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
遺伝子導入ベクターの開発とin vivo応用
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Endothelial Modulation of Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Histogenesis of Rat Lung Tumors induced by N-Nitrosodiethylamine (DEN)Principal Investigator
- Principal Investigator
  
  HASHIMOTO Shuichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyushu University
末梢性肺腺癌の発生病理ならびに組織亜型分類に関する分子病理学的研究Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
肺癌発生における環境要因に関する日米中国の比較研究
- Principal Investigator
  
  重松信昭
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Overseas Scientific Research
- Research Institution
  Kyushu University

All 2013 2003

All Journal Article

[Journal Article] 免疫組織化学的染色法;講座研究手法入門:生化学的・免疫学的実験法2013
- Author(s)
  橋本修一、中川和憲、Barry R Stripp
- Journal Title
  
  呼吸
  
  Volume : 32巻12号 Pages : 1162-1175
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 発達肺および傷害再生肺における肺上皮分化制御機構-肺幹細胞生物学の進歩と肺再生医療への礎–日本肺サーファクタント2013
- Author(s)
  橋本修一
- Journal Title
  
  界面医学会雑誌
  
  Volume : 44巻 Pages : 2-15
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 発達肺および傷害再生肺における肺上皮分化制御機構 - 肺幹細胞生物学の進歩と肺再生医療への礎 -2013
- Author(s)
  橋本　修一
- Journal Title
  
  日本肺サーファクタント・界面医学会雑誌
  
  Volume : 44 Pages : 2-15
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 免疫組織化学的染色法2013
- Author(s)
  橋本　修一、中川　和憲、Barry R. Stripp
- Journal Title
  
  呼吸
  
  Volume : 32 Pages : 1162-1175
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 免疫組織化学的染色法;講座研究手法入門:生化学的・免疫学的実験法2013
- Author(s)
  橋本修一、中川和憲、Barry R Stripp
- Journal Title
  
  呼吸
  
  Volume : 32巻12号 Pages : 1162-1175
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 発達肺および傷害再生肺における肺上皮分化制御機構-肺幹細胞生物学の進歩と肺再生医療への礎–日本肺サーファクタント2013
- Author(s)
  橋本修一
- Journal Title
  
  界面医学会雑誌
  
  Volume : 44巻 Pages : 2-15
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 発達肺および傷害再生肺における肺上皮分化制御機構 - 肺幹細胞生物学の進歩と肺再生医療への礎 -2013
- Author(s)
  橋本　修一
- Journal Title
  
  日本肺サーファクタント・界面医学会雑誌
  
  Volume : 44 Pages : 2-15
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 免疫組織化学的染色法2013
- Author(s)
  橋本　修一、中川　和憲、Barry R. Stripp
- Journal Title
  
  呼吸
  
  Volume : 32 Pages : 1162-1175
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] Recombinant Sendai virus vectors for activated T lymphocytes.2003
- Author(s)
  Okano S, Yonemitsu Y, Nagata S, Sata S, Onimaru M, Nakagawa K, Tomita Y, Kishihara K, Hashimoto S, Nakashima Y, Sugimachi K, Hasegawa M, Sueishi K
- Journal Title
  
  Gene Ther 10(16)
  
  Pages : 1381-1391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Journal Article] Recombinant Sendai virus vectors for activated T lymphocytes.2003
- Author(s)
  Okano S, Yonemitsu Y, Nagata S, Sata S, Onimaru M, Nakagawa K, Tomita Y, Kishihara K, Hashimoto S, Nakashima Y, Sugimachi K, Hasegawa M, Sueishi K
- Journal Title
  
  Gene Ther 10(16)
  
  Pages : 1381-1391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078

1. SUEISHI Katsuo (70108710)

# of Collaborated Projects : 11results

# of Collaborated Products : 2results
2. NAKAGAWA Kazunori (50217668)

# of Collaborated Projects : 9results

# of Collaborated Products : 2results
3. NAKASHIMA Yutaka (50135349)

# of Collaborated Projects : 6results

# of Collaborated Products : 2results
4. KONO Shinji (20225379)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
5. TASHIRO Yoshihiko (10188237)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. YONEMITSU Yoshikazu (40315065)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
7. ISHIBASHI Hiroaki (90254630)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. ITO Takaaki (70168392)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. HARA Nobuyuki (90038802)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. SAKAMOTO Taiji (10235179)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 重松信昭 (40038683)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 信友浩一 (90037424)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 光山孝志 (00253419)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 矢川克郎 (90183665)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. 広畑富雄 (50102075)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. STEVEN Piant

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 冨安幸博

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

HASHIMOTO Shuichi 橋本 修一

Research Projects

Research Products

Co-Researchers

肺癌におけるR-spondin-Lgr6シグナル系の発現・機能解析Principal InvestigatorOngoing

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Analysis of beta-Catenin/Sox2/p63 Signal Pathway in Lung Epithelial Differentiation and TumorigenesisPrincipal Investigator

Principal Investigator

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肺癌におけるFGFs、FGFRsおよびSproutysの発現・機能解析Principal Investigator

Principal Investigator

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Principal Investigator

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Principal Investigator

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ヒト肺腺癌と前癌病変(AAH)における発癌関与遺伝子のDNAマイクロアレイ解析Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

Project Period (FY)

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Principal Investigator

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Gene Abberation Analysis in Precancerous Lesion of the Lung Adenocarcinoma by Laser Microdissection SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

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Histogenesis of Rat Lung Tumors induced by N-Nitrosodiethylamine (DEN)Principal Investigator

HASHIMOTO Shuichi 橋本修一