HASHIMOTO Shuichi 橋本修一

… Alternative Names

橋本修一ハシモトシュウイチ

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Researcher Number	00243931
Affiliation (based on the past Project Information) *help	2018 – 2021: 福岡歯科大学, 口腔歯学部, 教授 2016: 福岡歯科大学, 口腔歯学部, 教授 2014 – 2015: 福岡歯科大学, 歯学部, 教授 2013: 熊本大学, 大学院生命科学研究部(医), 准教授 2012: 熊本大学, 大学院生命科学研究部機能病理学分野, 准教授 … More 2011: 熊本大学, 生命科学研究部, 准教授 2004: 九大, 医学(系)研究科(研究院), 助手 2002 – 2003: 九州大学, 大学院・医学研究院, 助手 2000: 九大, 医学(系)研究科, 助手 1999: Kyushu University, Graduate School of Medicine, Assistant, 大学院・医学系研究科, 助手 1998: 九州大学, 医学部, 助手 1993 – 1996: 九州大学, 医学部, 助手 1987: 九州大学, 医学部, 医員 Less
Review Section/Research Field	Principal Investigator Human pathology / Human pathology / Experimental pathology / Respiratory organ internal medicine / Basic Section 49020:Human pathology-related / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Human pathology / Experimental pathology / Human pathology
Keywords	Principal Investigator CC10 / SP-A / 肺腺癌 / beta-catenin / N-Nitrosodiethylamine (DEN) / Piperonylbutoxide (PIP) / Lung tumor / PCNA / RAT / proSP-C … More / p53 / クララ細胞 / SP-B / 発生母細胞 / 免疫組織化学 / 予後因子 / Lung / Cancer / Epithelium / Differentiation / Stem Cell / Sox2 / p63 / Sox9 / Notch / Stem cell / Airway epithelium / 肺癌 / 幹細胞 / Lgr6 / R-spondin / Wnt / N-nitrosodiethylamine / 肺腫瘍 / ラット / サーファクタント・アポ蛋白 / 異型腺腫様過形成(AAH) / Ki-67(MIB-1) / マイクロディセクション / レーザーマイクロディセクション / Lung Cancer / Atypical Adenomatous Hyperplasia (AAH) / Ki-67 (MIB-1) / Microdissection / PKM2 / TGIF2 / EMT / Warburg effect / 口腔上皮性異型性 / 口腔扁平上皮癌 / 口腔上皮性異形成 / Oral SCC / Oral cancer / Immunologic dormancy / Cancer stemness / IDO1 / Kynurenine … More Except Principal Investigator 遺伝子治療 / 血管新生 / VEGF / 遺伝子導入 / p53 / 血管リモデリング / 血管内皮細胞 / Endothelial Cell / Gene Transfer / Angiogenesis / 肺腺がん / 動脈硬化 / NO / atherosclerosis / angiogenesis / Sev / FGF-2 / MCP-1 / 血栓症 / 転写因子 / Gene Therapy / Vascular Remodeling / HVJ-catinic liposome / HVJ-liposome / 血管 / 肝 / 導入効率 / EP-24.16 / 肺腺癌 / 肺扁平上皮癌 / エンドペプチダーゼ / 転移 / マイクロディセクション / 肺線がん / 肺異型腺腫様過形成 / PCR-SSCP / 末梢型肺腺がん / MMP / TIMP-2 / 浸潤能 / プロテオミクス / 基質膜抗原 / 病理標本 / プロテオーム解析 / 遺伝子解析 / 発癌 / 異型線腫様過形成 / II型肺胞上皮細胞 / 培養肺腫瘍細胞 / HVJ・liposome法 / アポトーシス / gene therapy / HVJ-lipsome method / apoptosis / 遺伝子導入ベクター / Sevベクター / PTCA / TGFβ^1 / 血管新生病 / デコイオリゴ / gene transfer vector / vascular remodeling / 一酸化窒素 / アンチセンス / リポソーム / デコイ / Antisense / Liposome / Transcription Factor / Decoy / シグナル伝達 / cross-talk sianal Less

Clarification of the immune mechanism for the entry of oral carcinomas into dormancyPrincipal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Fukuoka Dental College
口腔悪性腫瘍におけるPKM2の機能および関連因子間制御機構の解明Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Fukuoka Dental College
Expression and functional analyses of R-spondin-Lgr6 signaling pathway in lung cancerPrincipal Investigator
- Principal Investigator
  
  Hashimoto Shuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Fukuoka Dental College
Analysis of beta-Catenin/Sox2/p63 Signal Pathway in Lung Epithelial Differentiation and TumorigenesisPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Shuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kumamoto University
肺癌におけるFGFs、FGFRsおよびSproutysの発現・機能解析Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
病理標本におけるタンパク質発現動態からの分子病態解析の試み
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic process.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
ヒト肺腺癌と前癌病変(AAH)における発癌関与遺伝子のDNAマイクロアレイ解析Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
ディファレンシャルディスプレイを利用した病理標本の分子病態学的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Patho-physiological studies on cellular interaction in vascular injury and vascular remodeling
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
Trial research for practical use of the reagent for gene expression control by Decoy oligo nucleotide.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
腫瘍増殖におけるメタロエンドペプチダーゼEP-24.16の分子病態学的解析
- Principal Investigator
  
  中川和憲
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Molecular pathobiological Study on Endothelial Function Ocurring during Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
Gene Abberation Analysis in Precancerous Lesion of the Lung Adenocarcinoma by Laser Microdissection SystemPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Shuichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
遺伝子導入ベクターの開発とin vivo応用
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Endothelial Modulation of Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Histogenesis of Rat Lung Tumors induced by N-Nitrosodiethylamine (DEN)Principal Investigator
- Principal Investigator
  
  HASHIMOTO Shuichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyushu University
末梢性肺腺癌の発生病理ならびに組織亜型分類に関する分子病理学的研究Principal Investigator
- Principal Investigator
  
  橋本修一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
肺癌発生における環境要因に関する日米中国の比較研究
- Principal Investigator
  
  重松信昭
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Overseas Scientific Research
- Research Institution
  Kyushu University

All 2021 2020 2019 2018 2016 2013 2003

All Journal Article Presentation

[Journal Article] NFAT5 promotes oral squamous cell carcinoma progression in hyper-osmotic environment2021
- Author(s)
  Yoshimoto Shohei、Morita Hiromitsu、Matsuda Miho、Katakura Yoshinori、Hirata Masato、Hashimoto Shuichi
- Journal Title
  
  Laboratory Investigation
  
  Volume: 101 Pages: 38-50
- DOI
  10.1038/s41374-020-00486-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-20K18490, KAKENHI-PROJECT-20H03854, KAKENHI-PROJECT-17K11645, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17K18301
[Journal Article] Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids2020
- Author(s)
  Yoshimoto Shohei、Yoshizumi Junko、Anzai Hiromasa、Morishita Koichiro、Okamura Kazuhiko、Hiraki Akimitsu、Hashimoto Shuichi
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 13 Pages: 1-9
- DOI
  10.1242/dmm.045054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-20K10129, KAKENHI-PROJECT-20K18490, KAKENHI-PROJECT-17K18301
[Journal Article] Hypoxia-induced HIF-1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF-β-dependent EMT.2019
- Author(s)
  Shohei Yoshimoto, Fumie Tanaka, Hiromitsu Morita, Akimitsu Hiraki, Shuichi Hashimoto
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Pages: 7822-7832
- DOI
  10.1002/cam4.2667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-17K18301, KAKENHI-PROJECT-16K11713
[Journal Article] Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT and post-translationally repressing TGIF2.2018
- Author(s)
  Tanaka Fumie、Yoshimoto Shohei、Okamura Kazuhiko、Ikebe Tetsuro、Hashimoto Shuichi
- Journal Title
  
  oncotarget
  
  Volume: 9 Pages: 33745-33761
- DOI
  10.18632/oncotarget.25850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07033, KAKENHI-PROJECT-17K18301
[Journal Article] 免疫組織化学的染色法2013
- Author(s)
  橋本　修一、中川　和憲、Barry R. Stripp
- Journal Title
  
  呼吸
  
  Volume: 32 Pages: 1162-1175
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 免疫組織化学的染色法;講座研究手法入門:生化学的・免疫学的実験法2013
- Author(s)
  橋本修一、中川和憲、Barry R Stripp
- Journal Title
  
  呼吸
  
  Volume: 32巻12号 Pages: 1162-1175
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 発達肺および傷害再生肺における肺上皮分化制御機構-肺幹細胞生物学の進歩と肺再生医療への礎–日本肺サーファクタント2013
- Author(s)
  橋本修一
- Journal Title
  
  界面医学会雑誌
  
  Volume: 44巻 Pages: 2-15
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] 発達肺および傷害再生肺における肺上皮分化制御機構 - 肺幹細胞生物学の進歩と肺再生医療への礎 -2013
- Author(s)
  橋本　修一
- Journal Title
  
  日本肺サーファクタント・界面医学会雑誌
  
  Volume: 44 Pages: 2-15
- Data Source
  KAKENHI-PROJECT-23590466
[Journal Article] Recombinant Sendai virus vectors for activated T lymphocytes.2003
- Author(s)
  Okano S, Yonemitsu Y, Nagata S, Sata S, Onimaru M, Nakagawa K, Tomita Y, Kishihara K, Hashimoto S, Nakashima Y, Sugimachi K, Hasegawa M, Sueishi K
- Journal Title
  
  Gene Ther 10(16)
  
  Pages: 1381-1391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Presentation] NFAT5 enhances the oral squamous cell carcinoma progression in the hyper-osmotic condition through the EGFR activation2020
- Author(s)
  Shohei Yoshimoto, Shuichi Hashimoto
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] HIF‐1α and ZEB1 are critical for the malignant transformation of ameloblastoma2020
- Author(s)
  Shohei Yoshimoto, Fumie Tanaka, Hiromitsu Morita, Akimitsu Hiraki, Shuichi Hashimoto
- Organizer
  第109回日本病理学会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] IFN-γ-triggered triptophan-IDO1-kynurenine-AhR signal activation induces immunologic tumor dormancy in OSCC2020
- Author(s)
  Hiromasa Anzai, Shohei Yoshimoto, Kenichiro Hashimoto, Akimitsu Hiraki, Shuichi Hashimoto
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] IFN-γ-triggered triptophan-IDO1-kynurenine-AhR signal activation induces immunologic tumor dormancy in human oral squamous cell carcinomas2020
- Author(s)
  Hiromasa Anzai, Shohei Yoshimoto, Akimitsu Hiraki, Shuichi Hashimoto
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT2019
- Author(s)
  吉本尚平、田中文恵、岡村和彦、池邉哲郎、橋本修一
- Organizer
  第108回日本病理学会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT2019
- Author(s)
  Fumie Tanaka1, Shohei Yoshimoto, Kazuhiko Okamura, Tetsuro Ikebe, Shuichi Hashimoto
- Organizer
  第108回日本病理学会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] Hypoxia induced HIF-1α and ZEB1 are critical for the malignant transformation of ameloblastoma2019
- Author(s)
  吉本尚平, 森田浩光, 橋本修一
- Organizer
  第61回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18K07033
[Presentation] Stem Cell Marker Lgr6 Expression Analysis in Lung and Oral Cancers2016
- Author(s)
  橋本修一, 白羽英則, 高山浩一, 中川和憲, 中西洋一
- Organizer
  第23回日本歯科医学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-26460436

1. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 11 results

# of Collaborated Products: 1 results
2. NAKAGAWA Kazunori (50217668)

# of Collaborated Projects: 10 results

# of Collaborated Products: 2 results
3. NAKASHIMA Yutaka (50135349)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
4. KONO Shinji (20225379)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. TASHIRO Yoshihiko (10188237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YONEMITSU Yoshikazu (40315065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. ISHIBASHI Hiroaki (90254630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ITO Takaaki (70168392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKANISHI Yoichi (20172356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TAKAYAMA Koichi (50274444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SHIRAHA Hidenori (40379748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. HARA Nobuyuki (90038802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SAKAMOTO Taiji (10235179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 重松信昭 (40038683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 信友浩一 (90037424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 光山孝志 (00253419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 矢川克郎 (90183665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 広畑富雄 (50102075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. STEVEN Piant

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 冨安幸博

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HIRAKI Akimitsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 吉本尚平

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
23. 平田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 松田美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 森田浩光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HASHIMOTO Shuichi 橋本 修一

橋本 修一 ハシモト シュウイチ

Research Projects

Research Products

Co-Researchers

Clarification of the immune mechanism for the entry of oral carcinomas into dormancyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔悪性腫瘍におけるPKM2の機能および関連因子間制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expression and functional analyses of R-spondin-Lgr6 signaling pathway in lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of beta-Catenin/Sox2/p63 Signal Pathway in Lung Epithelial Differentiation and TumorigenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

肺癌におけるFGFs、FGFRsおよびSproutysの発現・機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Principal Investigator

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ヒト肺腺癌と前癌病変(AAH)における発癌関与遺伝子のDNAマイクロアレイ解析Principal Investigator

Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Gene Abberation Analysis in Precancerous Lesion of the Lung Adenocarcinoma by Laser Microdissection SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

HASHIMOTO Shuichi 橋本修一

橋本修一ハシモトシュウイチ