NAKASHIMA Yutaka 中島豊

Researcher Number	50135349
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External Links
Affiliation (based on the past Project Information) *help	1999 – 2003: Graduate School of Med.Sci.KYUSHU UNIVERSITY Assoc.Prof., 大学院・医学研究院, 助教授 2000: KYUSHU UNIVERSITY, Graduate School of Medical Science, Associate Professor, 大学院・医学系研究院, 助教授 1999: 九州大学, 大学院・医学系研究科, 助教授 1991 – 1998: 九州大学, 医学部, 助教授 1989 – 1990: 九州大学, 医学部, 講師 1988: 九州大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Human pathology / Experimental pathology Except Principal Investigator Human pathology / Experimental pathology / Experimental pathology / Circulatory organs internal medicine / Public health/Health science
Keywords	Principal Investigator 高血圧 / 動脈硬化 / VCAM-1 / ICAM-1 / PECAM-1 / shear stress / atherosclerosis / 解離性大動脈癌 / ラット / βーaminopropionitrile … More / 弾性線維 / 透過電顕 / 走査電顕 / ラチリズム / 解離性大動脈瘤 / β-aminopropionitrile / apolipoprotein E 欠損マウス / in situ 免疫染色 / 単球 / apollipoproteinE欠損マウス / E-selectin / P-selectin / in situ免疫染色 / 接着因子 / 遺伝子欠損マウス / in situ免疫法 / ApoE-deficient mouse / in situ immnocytochemistry / monocyte / 疫学調査 / 危険因子 / 高脂血症 / 肥満 / 冠状動脈 / 久山町 / 肥満 / epidemiology / risk factors / hyperlipidemia / obesity / hypertension / coronary artery / Hisayama study … More Except Principal Investigator 動脈硬化 / VEGF / 血管新生 / 遺伝子導入 / FGF-2 / 遺伝子治療 / 血管内皮細胞 / Angiogenesis / 血管リモデリング / MCP-1 / SeV / atherosclerosis / gene therapy / angiogenesis / Endothelial Cell / Gene Transfer / p53 / 内皮細胞 / PTCA / 血栓症 / Sev / 血管新生病 / HGF / 組織因子 / 平滑筋細胞 / 増殖因子 / 血管平滑筋細胞 / 血栓 / サイトカイン / 接着蛋白 / デコイオリゴ / Sevベクター / センダイウイルス / マクロファージ / IL-1 / Endothelial cells / Macrophages / Gene transfer / NO / 転写因子 / vascular remodeling / Gene Therapy / Vascular Remodeling / gene transfer / センダイウイルスベクター / 重症虚血肢 / プラスミノゲン・アクチベ-タ- / 免疫組織化学 / 接着斑 / 低酸素 / HVJ-catinic liposome / HVJ-liposome / 血管 / 肝 / 導入効率 / 動脈リモデリング / サイトメガロウイルス / Tie-2 / p53遺伝子 / HVJ-リポゾーム / 炎症 / PTCA後再狭窄 / TGFβ_1 / ecNOS / 下肢虚血 / 関節リウマチ / Sprouty-2 / SIV / IL-17 / 転移 / 擬固 / 線溶 / プラスミノゲン / プラスミノゲン・アクチベーター / 腫瘍間質 / コラゲナーゼ / 冠動脈狭窄 / 冠動脈攣縮 / 再狭窄 / 血小板 / セロトニン / X線照射 / 内膜肥厚 / PTcA / 内皮細胞依存性血管弛緩反応 / 心筋虚血 / 冠動脈硬化 / 冠血行再建術 / ミニ豚 / 冠動脈造影法 / coronary artery stenosis / coronary artery spasm / restenosis / platelet / serotonin / X-ray irradiation / IL-1レセプターアンタゴニスト / IL‐1 / IL‐1レセプターアンタゴニスト / Thrombus / Atherosclerosis / Tissue factor / IL-1ra / 血管内皮増殖因子 / 動脈内膜障害・修復 / HVJ・リポゾーム / ヒトCMV・IE遺伝子 / Smooth muscle cells / Athero-and arteriosclerpsis / Thrombosis / Angiogensis / Vascular endothelial growth facator / HVJ・liposome法 / アポトーシス / HVJ-lipsome method / apoptosis / 血管内皮細胞増殖因子 / 血栓形成 / Atheroscrelosis / 遺伝子導入ベクター / TGFβ^1 / gene transfer vector / 高インスリン血症 / インスリン抵抗性 / 高血圧 / 耐糖能異常 / 脂質代謝異常 / アルコール / 虚血性心疾患 / 腎機能 / インスリン抵抗性症候群 / アルコール摂取 / 前向き追跡研究 / 一般住民 / 危険因子 / 疫学研究 / 血清脂質 / 脳梗塞 / 予後 / 食事性因子 / 疫学調査 / 飽和脂肪酸 / hyperinsulinemia / insulin resistance / hypertension / glucose intolerance / dyslipidemia / alcohol / coronary heart disease / renal function / 一酸化窒素 / 安全性 / 血管新生療法 / SeVベクター / 移植 / safety / therapeutic angiogenesis / アンチセンス / リポソーム / デコイ / Antisense / Liposome / Transcription Factor / Decoy / ヒトサイトメガロウイルス / 血管炎 / 炎症性腹部大動脈瘤 / 前初期遺伝子 / Human cytomegalovirus / Vasculitis / レンチウイルスベクター / 肺高血圧症 / 網膜色素変性症 / 慢性関節リウマチ / 嚢胞性線維症 / recombinant Seiidai virus vector / critical limb ischemia / 血管新生因子の階層性 / 組織幹細胞 / ウイルスベクター / angiogenic hierarchy / tissue stem cell / 線維芽細胞増殖因子(FGF-2) / 血管・リンパ管新生 / VEGFファミリー / PDGFファミリー / PEDF / 血管新生遺伝子治療 / 抗血管新生療法 / センダイウイルスペクター / シグナル伝達 / cross-talk sianal Less

新規遺伝子導入ベクターを用いた慢性関節リウマチの治療法の開発
- Principal Investigator
  
  中川和憲
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
Hierarchical Regulation of Multiple Angiogenic Growth Factors During 'Functional' Angiogenesis In Vivo
- Principal Investigator
  
  YONEMITSU Yoshikazu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Moleculo-Pathological studies on intracellular cross-talk signal in angiogenic process.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
Molecular Pathophysiological Study on Endothelial Function Occurring during Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
動脈硬化発生・進展における血管内皮細胞機能に関する分子病理学的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Role of human cytomegalovirus infection and the expression of immediate early gene products (CMV-IE) in the pathogenesis of vascular lesion formations
- Principal Investigator
  
  YONEMITSU Yoshikazu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
Deveelopment of Novel Gene Theray Strategies Using Recombinant Sendai Virus.
- Principal Investigator
  
  YONEMITSU Yoshikazu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
動脈硬化発生・進展における血管内皮細胞機構に関する分子病理学的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Patho-physiological studies on cellular interaction in vascular injury and vascular remodeling
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
Regulation of Vascular Remodeling by Gene Transfer and Its Clinical Application : Exploration of Novel Gene Transfer Vector and Gene Therapy for Atherosclerosis, Angiogenic Diseases and Organ Infarction
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
Trial research for practical use of the reagent for gene expression control by Decoy oligo nucleotide.
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
動脈硬化発生・進展における血管内皮細胞機能に関する分子病理学的研究
- Principal Investigator
  
  据石克夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Molecular pathobiological Study on Endothelial Function Ocurring during Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
Pathological and Epidemiological Study of Coronary Atherosclerosis in Autopsy Subjects of Hisayama TownPrincipal Investigator
- Principal Investigator
  
  NAKASHIMA Yutaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KYUSHU UNIVERSITY
Actual state and prognosis of insulin resistanse syndrome in a general Japanese population : the Hisayama study
- Principal Investigator
  
  KIYOHARA Yutaka
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Kyushu University
動脈硬化発生・進展における血管内皮細胞機能に関する分子病理学的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Molecular pathological studies on physiological function of VEGF in atherosclerotic Vessels
- Principal Investigator
  
  NAKAGAWA Kazunori
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYUSHU UNIVERSITY
遺伝子導入ベクターの開発とin vivo応用
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Endothelial Modulation of Vascular Remodeling
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
in situ immunocytochemical study of adhesion molecules expressed on endothelium in atherosclerosis-prone mousePrincipal Investigator
- Principal Investigator
  
  NAKASHIMA Yutaka
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Molecular Pathology of Endothelial Function in the Regulation of Vascular Response to Injuries
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
Molecular Pathological Study on Endothelial Regulation of Blood-Vascular Wall Interaction
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
血管内血管新生における内皮細胞・平滑筋細胞相互反応に関する分子病理学的研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Mechanisms of Restenosis Following Coronary Angioplasty and its Prevention
- Principal Investigator
  
  TOMOIKE Hitonobu
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamagata University School of Medicine
  Kyushu University
血管壁凝固、線溶の活性化ならびに制御機構に関する分子病理学的研究
- Principal Investigator
  
  SUEISHI Katsuo
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
解離性大動脈瘤の発生機序に関する実験的研究Principal Investigator
- Principal Investigator
  
  中島豊
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
癌細胞表面の擬固、線溶系活性化機構と転移形成における意義に関する研究
- Principal Investigator
  
  居石克夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University

All 2005 2004 2003 2002

All Journal Article

[Journal Article] Angiogenesis/lymphangiogenesis and expression of lymphangiogenic factors in atherosclerotic intima of human coronary arteries.2005
- Author(s)
  Nakano T, Nakashima Y, Yonemitsu Y, Sumiyoshi S, Chen YX, Akishima Y, Ishii T, Iida M, Sueishi K
- Journal Title
  
  Hum Pathol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Journal Article] Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats.2004
- Author(s)
  Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, Hattori T, Nakashima Y, Kaibuchi K, Sueishi K, Takeshit A
- Journal Title
  
  Circ Res 94(3)
  
  Pages: 385-393
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Journal Article] Recombinant Sendai virus vectors for activated T lymphocytes.2003
- Author(s)
  Okano S, Yonemitsu Y, Nagata S, Sata S, Onimaru M, Nakagawa K, Tomita Y, Kishihara K, Hashimoto S, Nakashima Y, Sugimachi K, Hasegawa M, Sueishi K
- Journal Title
  
  Gene Ther 10(16)
  
  Pages: 1381-1391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Journal Article] Airway-directed gene transfer of interleukin-10 using recombinant Sendai virus effectively prevents post-transplant fibrous airway obliteration in mice.2003
- Author(s)
  Shoji F, Yonemitsu Y, Okano S, Yoshino I, Nakagawa K, Nakashima Y, Hasegawa M, Sugimachi K, Sueishi K
- Journal Title
  
  Gene Ther 10(3)
  
  Pages: 213-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Journal Article] Distributions of diffuse intimal thickening in human arteries : preferential expression in atherosclerosis-prone arteries from an early age.2002
- Author(s)
  Nakashima Y, et al.
- Journal Title
  
  Virchows Arch 441(3)
  
  Pages: 279-288
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370078
[Journal Article] Distributions of diffuse intimal thickening in human arteries: preferential expression in atherosclerosis-prone arteries from an early age.2002
- Author(s)
  Nakashima Y, Chen YX, Kinukawa N, Sueishi K
- Journal Title
  
  Virchows Arch. 441(3)
  
  Pages: 279-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370078

1. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 25 results

# of Collaborated Products: 5 results
2. NAKAGAWA Kazunori (50217668)

# of Collaborated Projects: 21 results

# of Collaborated Products: 2 results
3. YONEMITSU Yoshikazu (40315065)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
4. KONO Shinji (20225379)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
5. HASHIMOTO Shuichi (00243931)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
6. 石井寛 (10150400)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. TASHIRO Yoshihiko (10188237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KIYOHARA Yutaka (80161602)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ISHIBASHI Hiroaki (90254630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TOMOIKE Hitonobu (90112333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAKI Michiyasu (40191217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IKEDA Kozue (30184419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TONOOKA Ichiro (70164001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KUBOTA Isao (30161673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHIROTA Tomoko (80069781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KANEDA Yasufumi (10177537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KOMORI Kimihiro (40225587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SAKAMOTO Taiji (10235179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TSUZUKI Teruhisa (40155429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ISHIBASHI Tatsuro (30150428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. EGASHIRA Kensuke (60260379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 岡村孝 (30136436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 楢林英樹 (90208083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 稲生哲治 (10159965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 岡部靖彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKASHIMA Yutaka 中島 豊

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Pathological and Epidemiological Study of Coronary Atherosclerosis in Autopsy Subjects of Hisayama TownPrincipal Investigator

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NAKASHIMA Yutaka 中島豊