Hosokawa Nobuko 細川暢子

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HOSOKAWA Nobuko 細川暢子

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Researcher Number	00263153
Other IDs
Affiliation (Current)	2025: 京都大学, 医生物学研究所, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 京都大学, ウイルス・再生医科学研究所, 准教授 2016: 京都大学, ウイルス・再生医科学研究所, 准教授 2014 – 2015: 京都大学, 再生医科学研究所, 准教授 2006 – 2012: Kyoto University, Institute for Frontier Medical Sciences, Assoc. Professor 2001 – 2006: 京都大学, 再生医科学研究所, 助教授 1999 – 2000: 京都大学, 再生医科学研究所, 助手 1995 – 1996: 京都大学, 胸部疾患研究所, 助手
Review Section/Research Field	Principal Investigator Cell biology / Biological Sciences / Cell biology / Basic Section 44010:Cell biology-related Except Principal Investigator Cell biology / Biological Sciences / Cell biology
Keywords	Principal Investigator 小胞体 / 小胞体関連分解 / 糖タンパク質 / α-マンノシダーゼ / 小胞体品質管理 / タンパク質品質管理 / 細胞内輸送 / ER quality control / 品質管理機構 / 分子シャペロン … More / 糖蛋白質 / タンパク質分解 / レクチン / 小胞体シャペロンタンパク質 / ユビキチンリガーゼ / N結合型糖鎖 / 哺乳類細胞 / ライブイメージング / ライブセルイメージング / 小胞輸送 / 蛍光タンパク質 / ゴルジ装置 / コラーゲン / molecular chaperone / glycoprotein / intracellular transport / ER quality control (ERQC) / ER-associated protein degradation (ERAD) / endoplasmic reticulum (ER) / 糖タンパク / 品質管理 / α-mannosidase / ER stress / ER chaperone proteins / glycoproteins / ER(endoplasmic reticulum) / ERAD(ER associated degradation) / 小胞体マンノシターゼI / 小胞体ストレス / ER(endoplasmicreticulun) / ER marnosidase I / Glyooprotein / ERAD(ER associated degadation) / 小胞体マンノンダーゼ / 小胞体マンノシダーゼ / Glycoprotein / Quality Control of the Endoplasmic Reticulum / d-Mannosidase / ERADC Endoplasmic reticulum associated degradation / Endoplasmic Reticulum / 小胞体関連蛋白質分解 / 小胞体関係連分解 / 小胞体の品質管理機構 / ユビキチンリガーゼ複合体 / マンノシダーゼ / 動物細胞 / シャペロンタンパク質 / HRD1-SEL1L / 分子細胞生物学 / 糖鎖 / ユビキチンプロテアソーム系 / タンパク質 / HRD1-SEL1L複合体 / 分子シャペロンタンパク質 / 小胞体タンパク質分解 / 小胞体マンノシダーゼI / N型糖鎖 / 小胞体関連分野 … More Except Principal Investigator 分子シャペロン / EDEM / HSP47 / 品質管理 / ER associated degradation / Quality control / Molecular Chaperone / 小胞体関連分解 / コラーゲン / プロコラーゲン / ストレス蛋白質 / 分子シヤペロン / 小胞体関連分野 / molecular chaperone / procollagen / stress protein / 細胞内輸送 / ERdj5 / ジスルフィド結合 / 小胞体品質管理 / 小胞体 / レドックス / フォールディング / 結晶解析 / ノックアウトマウス / semi-permeabilized cell Less

Study on the intracellular transsport mechanism of collagensPrincipal Investigator
- Principal Investigator
  
  Hosokawa Nobuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kyoto University
Study on the protein quality control mechanism in the endoplasmic reticulumPrincipal Investigator
- Principal Investigator
  
  Hosokawa Nobuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
レクチンとシャペロンを介した小胞体タンパク質の品質管理Principal Investigator
- Principal Investigator
  
  細川暢子
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Analysis of the ubiquitin-ligase complex in the endoplasmic reticulum membrane that regulates endoplasmic reticulum-associated degradation in mammalsPrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Nobuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
ユビキチンリガーゼ複合体による小胞体関連タンパク質分解機構の研究Principal Investigator
- Principal Investigator
  
  細川暢子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Quality control mechanism of misfolded proteins
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyoto Sangyo University
  Kyoto University
糖タンパク質の小胞体品質管理機構Principal Investigator
- Principal Investigator
  
  細川暢子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Analysis of the molecular mechanism ofendoplasmic reticulum-associated protein degradation (ERAD)Principal Investigator
- Principal Investigator
  
  HOSOKAWA Nobuko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Quality control mechanism for positive and negative
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
糖鎖による蛋白質の小胞体品質管理機構の解析Principal Investigator
- Principal Investigator
  
  細川暢子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Functional analysis of EDEM which accelerates glycoprotein ERADPrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Nobuko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
Molecular mechanism of ER-related degradation
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Funcioal analysis of mouse EDEM, which eaocelerales gyocprotein ERADPrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Nobuko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
コラーゲン特異的分予シャペロンHSP47の構造と機能
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
A Search for a new chaperone proteins on the endoplasmic reticalPrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Nobuko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
コラーゲン特異的分子シャペロンによる癌細胞の浸潤転移制御
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
The role of collagen-specific molecular chaperone HSP47
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY

[Book] Sugar Chains (Eds. Suzuki T, Hotusbo K, Taniguchi N)2015
- Author(s)
  Nobuko Hosokawa and Tadashi Suzuki
- Total Pages
  288
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26440096
[Book] Methods in Enzymology Vol.480 (Ed.M.Fukuda)分担執筆2010
- Author(s)
  Hosokawa N, Kato K, Kamiya Y.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PUBLICLY-22020020
[Book] Methods in Enzymology Vol.480(Ed.M.Fukuda)分担執筆2010
- Author(s)
  Hosokawa N, Kato K, Kamiya Y.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] SEL1L degradation intermediates stimulate cytosolic aggregation of polyglutamine‐expanded protein2021
- Author(s)
  Hattori Tokuya、Hanafusa Ken、Wada Ikuo、Hosokawa Nobuko
- Journal Title
  
  The FEBS Journal
  
  Volume: - Issue: 15 Pages: 4637-4654
- DOI
  10.1111/febs.15761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06214
[Journal Article] Visualization of Procollagen IV Reveals ER-to-Golgi Transport by ERGIC-independent Carriers2020
- Author(s)
  Yuto Matsui, Yukihiro Hirata, Ikuo Wada, Nobuko Hosokawa
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 45 Issue: 2 Pages: 107-119
- DOI
  10.1247/csf.20025
- NAID
  130007879591
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07311, KAKENHI-PROJECT-18K06214
[Journal Article] SDF2-like protein 1 (SDF2L1) regulates the endoplasmic reticulum localization and chaperone activity of ERdj3 protein.2019
- Author(s)
  Hanafusa K, Wada I, Hosokawa N
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 294 Issue: 50 Pages: 19335-19348
- DOI
  10.1074/jbc.ra119.009603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07311, KAKENHI-PROJECT-18K06214
[Journal Article] ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing α-mannosidase-like protein 3 (EDEM3)2018
- Author(s)
  Yu S, Ito S, Wada I, Hosokawa N
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 27 Pages: 10663-10674
- DOI
  10.1074/jbc.ra118.003129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07311, KAKENHI-PROJECT-18K06214
[Journal Article] Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L2016
- Author(s)
  Hoshikawa N, Wada I
- Journal Title
  
  FEBS Journal
  
  Volume: 283 Issue: 1 Pages: 157-172
- DOI
  10.1111/febs.13564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10340, KAKENHI-PROJECT-26440096, KAKENHI-PROJECT-15K14462
[Journal Article] Endoplasmic reticulum lectinXTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsinvariant2013
- Author(s)
  T. Fujimori, Y. Kamiya, K. Nagata, K. Kato &N. Hosokawa
- Journal Title
  
  FEBS J
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Endoplasmic reticulum lectin XTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsin variant2013
- Author(s)
  Fujimori T, Kamiya Y, Nagata K, Kato K, Hosokawa N*
- Journal Title
  
  FEBS J
  
  Volume: Vol. 280 Issue: 6 Pages: 1563-1575
- DOI
  10.1111/febs.12157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183, KAKENHI-PROJECT-24249002
[Journal Article] SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates2011
- Author(s)
  Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 16929-16939
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020020
[Journal Article] SEL1L critically determines the stability of the HRD1-SEL1L ERAD complex to optimize the degradation kinetics of ERAD substrates.2011
- Author(s)
  Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020020
[Journal Article] SEL1L critically determines the stability of the HRD1-SEL1L ERAD complex to optimize the degradation kinetics of ERAD substrates.2011
- Author(s)
  Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates2011
- Author(s)
  Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, and Hosokawa N*
- Journal Title
  
  J. Biol. Chem
  
  Volume: Vol. 286 Issue: 19 Pages: 16929-16939
- DOI
  10.1074/jbc.m110.215871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] ERAD(小胞体関連分解)を制御するレクチンOS-9とXTP3-B2011
- Author(s)
  細川暢子
- Journal Title
  
  生化学
  
  Volume: Vol. 83, No.1 Pages: 44-49
- NAID
  10029067257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates2011
- Author(s)
  Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 16929-16939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] The role of MRH domain-containing lectins in ERAD.2010
- Author(s)
  Hosokawa N*, Kamiya Y, Kato K
- Journal Title
  
  Glycobiology
  
  Volume: Vol. 20 Issue: 6 Pages: 651-660
- DOI
  10.1093/glycob/cwq013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] EDEM1 accelerates the trimming of α1, 2-linked mannose on the C branch of N-glycans.2010
- Author(s)
  Hosokawa N, Tremblay LO, Sleno B, Kamiya Y, Wada I, Kato K, Nagata K, Herscovics A.
- Journal Title
  
  Glycobiology
  
  Volume: 20 Pages: 567-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] EDEM1 accelerates the trimming of α1, 2-linked mannose on the C branch of N-glycans.2010
- Author(s)
  Hosokawa N, Tremblay LO, Sleno B, Kamiya Y, Wada I, Kato K, Nagata K, Herscovics A.
- Journal Title
  
  Glycobiology
  
  Volume: 20 Pages: 567-575
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020020
[Journal Article] EDEM1 accelerates the trimming of α1,2-linked mannose on the C branch of N-glycans2010
- Author(s)
  Hosokawa N*, Tremblay LO, Sleno B, Kamiya Y, Wada I, Kato K, Nagata K, and Herscovics A
- Journal Title
  
  Glycobiology
  
  Volume: Vol. 20 Issue: 5 Pages: 567-575
- DOI
  10.1093/glycob/cwq001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] The role of MRH domain-containing lectins in ERAD.2010
- Author(s)
  Hosokawa N, Kamiya Y, Kato K.
- Journal Title
  
  Glycobiology
  
  Volume: 20 Pages: 651-660
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020020
[Journal Article] Mannose 6-phosphate receptor homology domain-containing lectins in mammalian endoplasmic reticulum-associated degradation2010
- Author(s)
  Hosokawa N*, Kato K, Kamiya Y
- Journal Title
  
  Methods in Enzymology
  
  Volume: Vol.480 Pages: 181-197
- DOI
  10.1016/s0076-6879(10)80010-2
- ISBN
  9780123809995
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] The role of MRH domain-containing lectins in ERAD.2010
- Author(s)
  Hosokawa N, Kamiya Y, Kato K.
- Journal Title
  
  Glycobiology
  
  Volume: 20 Pages: 651-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570183
[Journal Article] Human 0S-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans2009
- Author(s)
  N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato, K. Nagata
- Journal Title
  
  J. Biol. Chem. 284(25)
  
  Pages: 17061-17068
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans2009
- Author(s)
  N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato & K. Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 284(25) Issue: 25 Pages: 17061-17068
- DOI
  10.1074/jbc.m809725200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PLANNED-20107004
[Journal Article] Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans2009
- Author(s)
  N.Hosokawa, et al.
- Journal Title
  
  J.Biol.Chem. 284(25)
  
  Pages: 17061-17068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF5082008
- Author(s)
  D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D. M. Cyr, K. Tanaka, K. Iwai and K. Nagata
- Journal Title
  
  Mol. Biol. Cell.
  
  Volume: 19 Issue: 4 Pages: 1328-1336
- DOI
  10.1091/mbc.e07-06-0601
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP.2008
- Author(s)
  N. HOSOKAWA, et al.
- Journal Title
  
  Biol J. Chem. 283(30)
  
  Pages: 20914-20924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L uhiouitin ligase complex and BiP2008
- Author(s)
  Hosokawa N, Wada I, Nagasawa K, Moriyama T, Okawa K, and Nagata K.
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 20914-20924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044022
[Journal Article] Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP2008
- Author(s)
  N.Hosokawa, I.Wada, K.Nagasawa, T.Moriyama, K.Okawa, and K.Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 283(30) Issue: 30 Pages: 20914-20924
- DOI
  10.1074/jbc.m709336200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF5082008
- Author(s)
  D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D. M. Cyr, K. Tanaka, K. Iwai, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 19
  
  Pages: 1328-1336
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Targeted disruption of Hsp110/105 gene protects against ischemic stress2008
- Author(s)
  Nakamura J, Fujimoto M, Yasuda K, Takeda.K, Akira. S, Hatayama T, Takagi Y, Nozaki K, Hosokawa N, Nagata K.
- Journal Title
  
  Stroke 39
  
  Pages: 2853-2859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044022
[Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTR ΔF508.2008
- Author(s)
  Morito D, Hirao K, Oda Y, Hosokawa N, Tokunaga F, Cyr D M, Tanaka K, 〓 K 〓 K
- Journal Title
  
  Molecular Biology of the Cell (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044022
[Journal Article] Gp78 cooperatps with RMA1 in ER-associated degradation of CFTR AF5082008
- Author(s)
  Morito D, Hirao K, Oda Y, Hosokawa N, Tokunaga F, Cyr D M, Tanaka K, Iwai K, Nagata K.
- Journal Title
  
  Molecular Biology of the Cell 19
  
  Pages: 1328-1336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044022
[Journal Article] M-type lectins as novel components of secretory pathways.2007
- Author(s)
  Hosokawa N, Nagata K
- Journal Title
  
  in "Animal Lectins : A Funcional View" (in press)
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] M-type lectins as novel components of secretory pathways.2007
- Author(s)
  Hosokawa N, Nagata K
- Journal Title
  
  Animal Lectins : A Funcional View (in press)
- Data Source
  KAKENHI-PROJECT-17046009
[Journal Article] Stimulation of ERAD of misfolded null Hong Kong α 1-antitrypsin by Golgi α 1,2-mannosidases.2007
- Author(s)
  Hosokawa N, You Z, Tremblay L O, Nagata K, Herscovics A.
- Journal Title
  
  Biochemical and Biophysical Research Communications 362
  
  Pages: 626-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044022
[Journal Article] Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation.2007
- Author(s)
  Nagasawa K, Higashi T, Hosokawa N, Kaufman RJ, Nagata K
- Journal Title
  
  EMBO Reports (in press)
- Data Source
  KAKENHI-PROJECT-17046009
[Journal Article] M-type lectins as novel components of secretory pathways.2007
- Author(s)
  Hosokawa N et al.
- Journal Title
  
  in "Animal Lectins : A Funcional View" (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] Simultaneous induction of the four subunits of TRAP complex by ER stress accelerates ER degradation.2007
- Author(s)
  Nagasawa K, Higashi T, Hosokawa N, Kaufman R J, Nagata K.
- Journal Title
  
  EMBO Reports 8
  
  Pages: 483-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044022
[Journal Article] Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation.2007
- Author(s)
  Nagasawa K, Higashi T, Hosokawa N, Kaufman RJ, Nagata K
- Journal Title
  
  EMBO Reports (in press)
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  N. Hosokawa
- Journal Title
  
  Genes Cells. 11(5)
  
  Pages: 465-476
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded a 1-antitrypsin.2006
- Author(s)
  N.Hosokawa
- Journal Title
  
  Genes Cells. 11(15)
  
  Pages: 465-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16207013
[Journal Article] EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.2006
- Author(s)
  Hirao K, Natsuka Y, Tamara T, Wada I, Morito D, Natsuka S, Romero P, Sleno B, Tremblay LO, Herscovics A, Nagata K, Hosokawa N
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 9650-9658
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.2006
- Author(s)
  Hirao K, Natsuka Y, Tamura T, Wada I, Morito D, Natsuka S, Romero P, Sleno B, Tremblay LO, Herscovics A, Nagata K, Hosokawa N
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 9650-9658
- Data Source
  KAKENHI-PROJECT-17046009
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  N.HOSOKAWA et al.
- Journal Title
  
  Genes Cells. 11.15
  
  Pages: 465-476
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  Hosokawa N, Wada I, Natsuka Y, Nagata K
- Journal Title
  
  Genes to Cells 11
  
  Pages: 465-476
- Data Source
  KAKENHI-PROJECT-17046009
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  N. Hosokawa
- Journal Title
  
  Genes Cells. 11 (15)
  
  Pages: 465-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  Hosokawa N, et al.
- Journal Title
  
  Genes to Cells 11
  
  Pages: 465-476
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  Hosokawa.N., et al.
- Journal Title
  
  Genes to Cells (in press)
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  Hosokawa.N., et al.
- Journal Title
  
  Genes to Cells (in press)
- Data Source
  KAKENHI-PROJECT-17046009
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α 1-antitrypsin.2006
- Author(s)
  N.Hosokawa
- Journal Title
  
  Genes Cells. 11(15)
  
  Pages: 465-476
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16207013
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin.2006
- Author(s)
  Hosokawa N, Wada I, Natsuka Y, Nagata K
- Journal Title
  
  Genes to Cells 11
  
  Pages: 465-476
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α 1-antitrypsin.2006
- Author(s)
  N.HOSOKAWA et al.
- Journal Title
  
  Genes Cells. 11.15
  
  Pages: 465-476
- Data Source
  KAKENHI-PROJECT-16207013
[Journal Article] Enhancement of endoplasmic reticulum (ER) degradation of misfolded null Hong Kong α1-antitrypsin by human ER Mannosidase I.2003
- Author(s)
  Hosokawa, N. et al.
- Journal Title
  
  Journal of Biological Chemistry 278
  
  Pages: 26287-26294
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570157
[Journal Article] Enhancement of endoplasmic reticulum(ER) degradation of misfolded null Hong Kong α1-antitrypsin by human ER mannosidase l.2003
- Author(s)
  N. Hosokawa
- Journal Title
  
  J. Biol. Chem. 278 (28)
  
  Pages: 26287-26294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] Enhancement of endoplasmic reticulum(ER) degradation of misfolded null Hong Kong α1-antitrypsin by human ER mannosidase I.2003
- Author(s)
  Hosokawa N, et al.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 26287-26294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570157
[Journal Article] Enhancement of endoplasmic reticulum(ER) degradation of misfolded null Hong Kong α 1-antitrypsin by human ER mannosidase I.2003
- Author(s)
  N. Hosokawa
- Journal Title
  
  J. Biol. Chen. 278(28)
  
  Pages: 26287-26294
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin has been accepted for publication.
- Author(s)
  N.HOSOKAWA et al.
- Journal Title
  
  Genes Cells. (in press)
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] Degradation of misfolded glycoproteins in the endoplasmic reticulum.
- Author(s)
  Hosokawa N.
- Journal Title
  
  In "Glycoscience Lab Manual" (Ed. N. Taniguchi, A. Suzuki, Y. Ito) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] M-type lectins as novel components of secretory pathways.
- Author(s)
  Hosokawa N, et al.
- Journal Title
  
  In "Animal Lectins : A Functional View"(Ed.) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570161
[Journal Article] EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded α1-antitrypsin has been accepted for publication.
- Author(s)
  N.HOSOKAWA et al.
- Journal Title
  
  Genes Cells. in press
- Data Source
  KAKENHI-PROJECT-16207013
[Presentation] Photon counting multiple histograms (PCMH) analysis of the ERdj3-SDF2L1 complex2020
- Author(s)
  Kuiper BP, Hanafusa K, Hosokawa N, Wada I
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06214
[Presentation] 小胞体膜タンパク質SEL1L分解産物は細胞質におけるタンパク質凝集体形成に関与する2020
- Author(s)
  細川暢子、和田郁夫
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18K06214
[Presentation] SDF2L1はERdj3の小胞体局在に必須であり、ERdj3のシャペロン活性を増幅する.2019
- Author(s)
  花房賢、細川暢子
- Organizer
  第19回日本蛋白質科学会年会、第71回日本細胞生物学会大会　合同年次大会
- Data Source
  KAKENHI-PROJECT-18K06214
[Presentation] ライブイメージング法を用いたIII型コラーゲン細胞内輸送メカニズムの解析.2019
- Author(s)
  平田幸大、松井優人、和田郁夫、細川暢子
- Organizer
  第19回日本蛋白質科学会年会、第71回日本細胞生物学会大会　合同年次大会
- Data Source
  KAKENHI-PROJECT-18K06214
[Presentation] EDEM3による小胞体マンノーストリミング活性はERp46によって制御される.2018
- Author(s)
  細川暢子、于尚誉、和田郁夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06214
[Presentation] SEL1Lタンパク質の分解機構2016
- Author(s)
  細川暢子、和田郁夫
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-26440096
[Presentation] 小胞体シャペロンタンパク質SDF2L1の機能解析.2015
- Author(s)
  田中雄大、藤森力、宮﨑恵理、花房賢、寿野良二、山﨑正幸、細川暢子
- Organizer
  BMB2015（第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会）
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440096
[Presentation] 小胞体膜に存在するHRD1-SEL1Lユビキチンリガーゼ複合体の機能解析.2015
- Author(s)
  細川暢子、和田郁夫
- Organizer
  BMB2015（第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会）
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440096
[Presentation] 新規小胞体シャペロンタンパク質の機能解析2014
- Author(s)
  細川暢子、藤森力
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良市
- Year and Date
  2014-06-01
- Data Source
  KAKENHI-PROJECT-26440096
[Presentation] Homeostasis and quality control of proteins in cells2012
- Author(s)
  Hosokawa N
- Organizer
  The Joint Symposium of the 7th International Symposium of the Institute Network and the 45th IDAC Symposium, the 2nd Symposium for Joint Usage/Research Center of Aging. "Research Frontiers for Smart Aging
- Place of Presentation
  仙台市
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Homeostasis and quality control of proteins in cells.2012
- Author(s)
  Hosokawa N
- Organizer
  The Joint Symposium of the 7th International Symposium of the Institute Network “Research Frontiers for Smart Aging”
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] 小胞体における糖鎖修飾とタンパク質品質管理機構2011
- Author(s)
  細川暢子
- Organizer
  第84回日本生化学会大会シンポジウム「糖鎖修飾:システムズバイオロジーへの展望」
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Roles of N-glycans in the regulation of mammalian glycoprotein quality control2011
- Author(s)
  Hosokawa, N.
- Organizer
  第34回日本分子生物学会年会シンポジウム"Glycoprotein quality control : Biosynthesis, molecular recognition and physiological roles of N-glycans"
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] 小胞体における糖鎖修飾とタンパク質品質管理機構2011
- Author(s)
  細川暢子
- Organizer
  第84回日本生化学会大会シンポジウム「糖鎖修飾:システムズバイオロジーへの展望」
- Place of Presentation
  京都市
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Lectins and enzymes that regulate the mammalian glycoprotein quality control.:2011
- Author(s)
  Hosokawa N
- Organizer
  The 31st Naito Conference on Glycan Expression and Regulation [II] Metabolites, Stress response, Microdomains, and Beyond
- Place of Presentation
  Sapporo (Japan)
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Functional analysis of MRH domain-containing lectin XTP3-B in the endoplasmic reticulum quality control2011
- Author(s)
  Fujimori, T., Kamiya, Y., Kato, K., Nagata, K., Hosokawa, N.
- Organizer
  The 31st Naito Conference on Glycan Expression and Regulation [II] Metabolites, Stress response, Microdomains, and Beyond
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Lectins and enzymes that regulate the mammalian glycoprotein quality control2011
- Author(s)
  Hosokawa, N.
- Organizer
  The 31st Naito Conference on Glycan Expression and Regulation [II] Metabolites, Stress response, Microdomains, and Beyond
- Place of Presentation
  Sapporo(招待講演)
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] The novel role of MRH domain-containing lectin XTP3-B in endoplasmic reticulum quality control2011
- Author(s)
  Fujimori, T., Kamiya, Y., Kato, K., Nagata, K., Hosokawa, N.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] 小胞体における糖鎖修飾とタンパク質品質管理機構2011
- Author(s)
  細川暢子
- Organizer
  第84回日本生化学会大会シンポジウム「糖鎖修飾:システムズバイオロジーへの展望」
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] The novel role of MRH domain-containing lectin XTP3-B in endoplasmic reticulum quality control.2011
- Author(s)
  Fujimori T, Kamiya Y, Kato K, Nagata K, Hosokawa N
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市)
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Roles of N-glycans in the regulation of mammalian glycoprotein quality control2011
- Author(s)
  Hosokawa, N.
- Organizer
  第34回日本分子生物学会年会シンポジウム"Glycoprotein quality control : Biosynthesis, molecular recognition and physiological roles of N-glycans"
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Lectins and enzymes that regulate the mammalian glycoprotein quality control2011
- Author(s)
  Hosokawa, N.
- Organizer
  The 31st Naito Conference on Glycan Expression and Regulation [II] Metabolites, Stress response, Microdomains, and Beyond
- Place of Presentation
  Sapporo(招待講演)
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Functional analysis of MRH domain-containing lectin XTP3-B in the endoplasmic reticulum quality control2011
- Author(s)
  Fujimori, T., Kamiya, Y., Kato, K., Nagata, K., Hosokawa, N.
- Organizer
  The 31st Naito Conference on Glycan Expression and Regulation [II] Metabolites, Stress response, Microdomains, and Beyond
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] Roles of N-glycans in the regulation of mammalian glycoprotein quality control.2011
- Author(s)
  Hosokawa N
- Organizer
  第34回日本分子生物学会年会シンポジウム"Glycoprotein quality control: Biosynthesis, molecular recognition and physiological roles of N-glycans"
- Place of Presentation
  横浜市
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Functional analysis of MRH domain-containing lectin XTP3-B in the endoplasmic reticulum quality control.2011
- Author(s)
  Fujimori T, Kamiya Y, Kato K, Nagata K, Hosokawa N
- Organizer
  The 31st Naito Conference on Glycan Expression and Regulation [II] Metabolites, Stress response, Microdomains, and Beyond
- Place of Presentation
  Sapporo (Japan)
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] The novel role of MRH domain-containing lectin XTP3-B in endoplasmic reticulum quality control2011
- Author(s)
  Fujimori, T., Kamiya, Y., Kato, K., Nagata, K., Hosokawa, N.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] Functional analysis of a mammalian lectin XTP3-B in the endoplasmic reticulum quality control.2010
- Author(s)
  藤森力、神谷由紀子、加藤晃一、永田和宏、細川暢子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Functional analysis of a mammalian lectin XTP3-B in the endoplasmic reticulum quality control.2010
- Author(s)
  藤森力、神谷由紀子、加藤晃一、永田和宏、細川暢子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] Functional analysis of a mammalian lectin XTP3-B in the endoplasmic reticulum quality control.2010
- Author(s)
  Fujimori T, Kamiya Y, Kato K, Nagata K, Hosokawa N
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  Nara (Japan)
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Formation of HRD1-SEL1L ubiquitin ligase complex that regulates the mammalian ERAD.2010
- Author(s)
  Hosokawa N, Iida Y, Okawa K, Nagata K.
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Functional analysis of a mammalian lectin XTP3-B in the endoplasmic reticulum quality control.2010
- Author(s)
  Fujimori T, Kamiya Y, Kato K, Nagata K, Hosokawa N.
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] Functional analysis of a mammalian lectin XTP3-B in the endoplasmic reticulum quality control.2010
- Author(s)
  Fujimori T, Kamiya Y, Kato K, Nagata K, Hosokawa N.
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Formation of HRD1-SEL1L ubiquitin ligase complex that regulates the mammalian ERAD2010
- Author(s)
  Hosokawa N, Iida K, Okawa K, Nagata K
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  Nara (Japan)
- Data Source
  KAKENHI-PROJECT-22570183
[Presentation] Formation of HRD1-SEL1L ubiquitin ligase complex that regulates the mammalian ERAD.2010
- Author(s)
  Hosokawa N, Iida Y, Okawa K, Nagata K.
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PUBLICLY-22020020
[Presentation] 新規レクチンによる小胞体タンパク質品質管理機構2008
- Author(s)
  細川暢子、和田郁夫、長澤孝治、森山達哉、大川克也、永田和宏
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19044022
[Presentation] Molecular and genetic analyses of a QTL for increased home-cage activity exclude Edem1 from the candidate genes（高自発活動マウスの分子遺伝学的解析によりEdem1は候補遺伝子より除外される）
- Author(s)
  Koide T, Ishii A, Hosokawa N, Nishi A（小出剛、石井亜矢子、細川暢子、西明紀）
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26440096

1. NAGATA Kazuhiro (50127114)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. INABA Kenji (10423039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HOSEKI Jun (40423058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAKAI Akira (60252516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 平芳一法 (80199108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. WALSH David A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. GREENSPAN Daniels

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUHN Klaus

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KLAUS Kuhn

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WALSH D.A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. GREENSPAN D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUHN K

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 和田郁夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 岩味健一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hosokawa Nobuko 細川 暢子

HOSOKAWA Nobuko 細川 暢子

Research Projects

Research Products

Co-Researchers

Study on the intracellular transsport mechanism of collagensPrincipal Investigator

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Study on the protein quality control mechanism in the endoplasmic reticulumPrincipal Investigator

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レクチンとシャペロンを介した小胞体タンパク質の品質管理Principal Investigator

Principal Investigator

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Research Institution

Analysis of the ubiquitin-ligase complex in the endoplasmic reticulum membrane that regulates endoplasmic reticulum-associated degradation in mammalsPrincipal Investigator

Principal Investigator

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Research Institution

ユビキチンリガーゼ複合体による小胞体関連タンパク質分解機構の研究Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Quality control mechanism of misfolded proteins

Principal Investigator

Project Period (FY)

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Research Institution

糖タンパク質の小胞体品質管理機構Principal Investigator

Principal Investigator

Project Period (FY)

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Analysis of the molecular mechanism ofendoplasmic reticulum-associated protein degradation (ERAD)Principal Investigator

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Quality control mechanism for positive and negative

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糖鎖による蛋白質の小胞体品質管理機構の解析Principal Investigator

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Functional analysis of EDEM which accelerates glycoprotein ERADPrincipal Investigator

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Molecular mechanism of ER-related degradation

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Funcioal analysis of mouse EDEM, which eaocelerales gyocprotein ERADPrincipal Investigator

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Hosokawa Nobuko 細川暢子

HOSOKAWA Nobuko 細川暢子