Nagata Kazuhiro 永田和宏

… Alternative Names

Researcher Number	50127114
Other IDs
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Affiliation (Current)	2021: 株式会社生命誌研究館, その他部局等, 館長・顧問
Affiliation (based on the past Project Information) *help	2020 – 2021: 株式会社生命誌研究館, その他部局等, 館長・顧問 2018 – 2019: 京都産業大学, 生命科学部, 教授 2017: 京都産業大学, 総合生命科学部生命システム学科, 客員教授 2010 – 2017: 京都産業大学, 総合生命科学部, 教授 2011: 京都大学, 再生医学研究所, 教授 … More
Review Section/Research Field	Principal Investigator Cell biology / Biological Sciences / Cell biology / Structural biochemistry / Experimental pathology / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields Except Principal Investigator Biological Sciences / Cerebral neurosurgery / Plastic surgery / 物質生物化学 … More
Keywords	Principal Investigator 分子シャペロン / ストレス蛋白質 / HSP47 / 熱ショック蛋白質 / コラーゲン / 小胞体 / EDEM / 品質管理 / 温熱療法 / プロコラーゲン … More Except Principal Investigator 分子シャペロン / アクチン / 細胞骨格 / 細胞接着 / ストレス蛋白質 / MMP / ストレス応答 / フィブロネクチン / チロシンリン酸化 / ビメンチン / 蛋白質のフォールディング / コラーゲン / タンパク質 / 品質管理 / UPR / ERAD / 脳動脈瘤 / TIMP / フォールディング / チューブリン / 細胞外マトリックス / インテグリン / プロテオグリカン / 熱ショック蛋白質 / molecular chaperone / 熱ショックタンパク質 / がん細胞の分化 / 微小管 / 中間フィラメント / 熱ショック応答 / 酸化ストレス / SOS応答 / 構造解析 / ATP / レセプター / アミロイド / ケロイド / 創傷治癒 / リン酸化 / 白血病細胞の分化 / ビトロネクチン / テネイシン / Fibronectin / stress response / シャペロン / stress protein / heat shock protein / タンパク質分泌 / ミトコンドリア / 小胞体 / iNOS / 動物モデル / IL-1β / TNF-α / 細胞生物学 / 現状分析 / 動向調査 / 細胞生物学と関連領域 / トリ肉腫ウィルス / HSP90 / カドヘリン / MAPキナ-ゼ / ポリホスホイノシタイド / 細胞周期 / 蛋白質・蛋白質相互作用 / 心筋虚血 / 再灌流 / 熱ショック転写因子 / 摘出潅流心 / ABC蛋白質 / 生活習慣病 / コレステロール / 糖尿病 / 癌 / トランスポーター / ABCタンパク質 / チャネル / 動脈硬化 / 膜タンパク質 / 遺伝病 / 胃癌 / スキルス / HSP47 / 線維芽細胞 / 間質制御 / 機能発現 / トランスロケータ / 脳血管障害学(脳動脈瘤クモ膜下出血炎症) / 脳神経疾患 / 脳血管障害 / クモ膜下出血 / NF-kB / 炎症 / 生体分子 / 予防医学 / 遺伝疫学 / 社会医学 / 衛生学 / 医歯薬学 / 複合体形成 / ATPase / CCT / HSP60 / 反応サイクル / タンパク質相互作用 / 構造変化 / 機能制御 / 基質特異性 / 核内タンパク質 / 有系分裂異常 / 有系分列の異常 / フォールボールエステルの作用 / 熱感受性 / 熱耐性 / Heat ShocR Protein / MRスペクトロスコピー / タンパク質のリン酸化 / 転移 / 微小管結合タンパク質 / 関節軟骨の修復 / 軟骨細胞の分化 / フィブロネクチンリセプタ- / コラ-ゲンゲル内培養 / フィブロンネクチン / フィブロンネクチンリセプタ- / Repair of Articular Cartilage / Differentiation of chondrocytes / Fibronectin receptor / Culture embedded in Collagen gel / ストレスタンパク質 / 転写調節 / ドメイン構造 / 温度感受性変異株 / 環境適応機構 / 生体防御機構 / 翻訳調節 / 蛋白質の分泌 / 転写制御 / 突然変異 / タンパク質間相互作用 / タンパク質キナ-ゼ / 分泌 / stress proteins / transcriptional control / domain structure / temperature-sensitive mutants / environmental adaptation / cell defense mechanism / ラミニン / サイトカイン / コンドロイチン硫酸 / コラ-ゲン / CELL ADHESION / EXTRACELLULAR MATRIX / COLLAGEN / LAMININ / FIBRONECTIN / PROTEOGLYCAN / INTEGRIN / CYTOKINE / 細胞内輸送 / 分子間結合 / 分子生物学 / Heat Shock Protein / Stress Protein / Molecular Chaperone / Structual Analysis / Collagen / Molecular Biology / Intracellnlar transport / Intermolecular Association / 蛋白質の細胞内輸送 / oxidative stress / SOS response / protein folding / intracellular transport of proteins / 抗-接着 / 細胞基質相互作用 / 接着シグナル / キナーゼ / 抗一接着 / Cell adhesion / Anti-adhesion / Integrin / Extracellular matrix / Cell-substratum inteaction / Proteoglycans / Adhesion signal / kinases / ミトコンドリア輸送 / アミロイドーシス / 葉緑体 / 膜透過 / 折り畳み / タンパク質の細胞内輸送 / Hsp70 / DnaJホモログ / カルネキシン / Hsp47 / アミロイド形成 / hsp70 / 小胞輸送 / hsp47 / folding / mitochondria import / secretory protein / amyloidosis / タンパク質分解 / 小胞体ストレス / 蛋白質の膜透過 / プリオン / 外膜リポタンパク質 / ジスルフィド形成 / ATP依存性プロテアーゼ / ストレス / 成熟 / 輸送 / 生物物理 / 蛋白質 / シャペロニン / タンパク質の膜透過 / molecular chperone / ER stress / translocation / prion / lipoprobin / disulfidebond formation / ATP dependent protease / endothelin / 遺伝子 / 血行力学的ストレス / 高血圧 / ラット / マウス / hemodynamic stress / cerebral aneurysmal / endothelium / gene / 顎関節症 / ストレス蛋白 / TMD / アポトーシス / 連鎖解析 / cerebral aneurysm / animal model / apoptosis / linkage analysis / 幹細胞 / リプログラミング / 組織幹細胞 / 多能性幹細胞 / Keloid / Wound Healing / Stem Cell / Reprogramming / 細胞伸展 / 糖タンパク質 / 血漿タンパク質 / 接着性糖タンパク質 / 細胞表面 / 細胞間マトリックス / 血液 / Cell attachment / Cell spreading / Glycoprotein / 神経老化 / HDAC6 / Mdm20 / オートファジー / mTOR / Akt / アセチル化修飾 / 老化 / アセチル化 / インスリンシグナル / ｍTORC2 / Rictor / アクチンリモデリング / ホメオスタシス / 老化制御因子 Less

Novel mechanism of the removal of reactive oxygen species in the ERPrincipal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  JT Biohistory Research Hall
  Kyoto Sangyo University
Regulation of neuronal ageing through the mTOR signaling by acetylation
- Principal Investigator
  
  YASUDA KUNIHIKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokai Gakuin University
  Nagasaki University
Mechanism of the maintenance of ER homeostasis by redox regulationPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto Sangyo University
Regulation of cellular functions by highly evolved two chaperonins
- Principal Investigator
  
  KUBOTA HIROSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Akita University
The elucidation of mechanisms for myseterin and its susceptibility variant and development of prevention program for moyamoya disease.
- Principal Investigator
  
  KOIZUMI Akio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto University
Integrated promotion of the researches in protein community
- Principal Investigator
  
  ENDO Toshiya
- Project Period (FY)
  2007 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Quality control mechanism of misfolded proteins in the ERPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Sangyo University
  Kyoto University
productive foldingと品質管理によるタンパク質の動態制御Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Clarification of mechanisms and role of inflammation cascade during cerebral aneurysm formation and development
- Principal Investigator
  
  HASHIMOTO Nobuo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  National Cardiovascular Center Research Institute
  Kyoto University
Analysis of the molecular function of HtrAl in keloid pathogenesis
- Principal Investigator
  
  NAITOH Motoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kyoto University
Quality control mechanism of misfolded proteinsPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyoto Sangyo University
  Kyoto University
Study on stroma of scirrhous gastric carcinoma Down reguration of collagen synthesis by siRNA in tumor tissue
- Principal Investigator
  
  KIKUCHI Shiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kitasato University
The molecular mechanisms of initiation, progression, rupture of cerebral aneurysms and development of a preventive treatment for it
- Principal Investigator
  
  HASHIMOTO Nobuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Investigation of keloid derived "stem-like" cells to clarify keloid pathogenesis.
- Principal Investigator
  
  NAITOH Motoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kyoto University
Quality control mechanism for positive and negativePrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Research for the role of stress protein in TMD
- Principal Investigator
  
  YAMAMURA Isao
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Osaka University
  Kyoto University
ABC蛋白の多機能性と生命維持機構
- Principal Investigator
  
  植田和光
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular mechanism of ER-related degradationPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
分子シャペロンによる基底膜分子構築の操作と癌細胞の浸潤・転移機能の解析Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Life of proteins: maturation, translocation, quality control in the cell
- Principal Investigator
  
  YOSHIDA Masasuke
- Project Period (FY)
  2001 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
Molecular mechanisms of cerebral aneurysmal formation
- Principal Investigator
  
  HASHIMOTO Nobuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyoto University
Two novel chaperone-like proteins involved in ER quality control mechanismPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
コラーゲン特異的分予シャペロンHSP47の構造と機能Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Regulation of cellular Function by molecular chaperonesPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1997 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  KYOTO UNIVERSITY
Roles of molecular chaperones in cell function
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1997 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
熱ショック転写因子群による分子シャペロンの転写制御機構Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
コラーゲン特異的分子シャペロンによる癌細胞の浸潤転移制御Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
セルピンファミリー蛋白質の分子シャペロン機能Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
分子シャペロンによる細胞機能制御Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
心筋虚血及び再灌流時におけるストレス応答とストレス蛋白質
- Principal Investigator
  
  野本慎一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University
Structure and function of stress proteinsPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University, Chest Disease Research Institute
STUDIES ON MOLECULAR MECHANISMS AND PHYSIOLOGICAL FUNCTIONS OF ANTI-CELL ADHESION
- Principal Investigator
  
  KIMATA Koji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  INSTITUTE FOR MOLECULAR SCIENCE OF MEDICINE,AICHI MEDICAL UNIVERSITY
The role of substrate-specific molecular chaperone in the trimerization of procollagen.Principal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
The role of collagen-specific molecular chaperone HSP47Principal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY
熱ショック・ストレス蛋白質の機能、発現機構とその制御Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Studies on the molecular mechanism of heat shock protein 47.
- Principal Investigator
  
  NAKAI Akira
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Institution
  Kyoto University
Molecular Mechanism of Stress Response
- Principal Investigator
  
  YAHARA Ichiro
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Regulatory mechanism of the expression of vimentin gene during the differentiation of leukemic cells.Principal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
熱ショック・ストレス蛋白質の機能、発現制御とその制御Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
がん細胞の特性を決定する細胞骨格異常の生化学的解析
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
白血病細胞の分化形質を支配するビメンチン遺伝子の発現調節Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
コラーゲンの小胞体・ゴルジ間輸送におけるHSP47の役割Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ストレス応答の分子機構
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
The role of stress proteins in the protein biosynthesis.Principal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
がん細胞の特性を決定する細胞骨格異常の生化学的解析
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
コラ-ゲンの小胞体・ゴルジ間輸送におけるHSP47の役割Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Stress response and stress protein
- Principal Investigator
  
  YAHARA Ichiro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  物質生物化学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
THE ANALYSIS OF CELL ADHESION SIGNALS : POSSIBLE CLINICAL APPLICATIONS
- Principal Investigator
  
  HAYASHI Toshikiko
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  広領域
- Research Institution
  UNIVERSITY OF TOKYO
癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
がん細胞の特性を決定する細胞骨格異常の生化学的解析
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
細胞生物学研究推進のための調査研究
- Principal Investigator
  
  田代裕
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  Kansai Medical University
Development of "Hybrid Type" Artificial Articular Cartilage
- Principal Investigator
  
  OKA Masanori
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kytot University
温熱耐性の発現機構の解明とその修飾に関する研究
- Principal Investigator
  
  田中敬正
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kansai Medical University
細胞がん化に伴う細胞骨格異常の分子生物学的解析
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
温熱耐性克服のための熱ショック蛋白質の基礎的研究Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
細胞接着因子と細胞機能調節
- Principal Investigator
  
  MASAO Hayashi
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Ochanomizu University
細胞がん化に伴なう細胞骨格異常の分子生物学的解析
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
がん細胞の温熱耐性における熱ショック蛋白質の役割Principal Investigator
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
細胞がん化に伴なう細胞骨格異常の分子生物学的解析
- Principal Investigator
  
  矢原一郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Physiology and Biochemistry of Fibronectin; Comprehensive Approaches from Basic to Clinical Studies.
- Principal Investigator
  
  MASAO Hayashi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  広領域
- Research Institution
  Ochanomizu University
Biochemical and molecular biological research for the function and regultion of a collagen receptorPrincipal Investigator
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University

[Book] Redox-dependent protein quality control in the ER : folding to degrasation2012
- Author(s)
  M. Hagiwara and K. Nagata
- Publisher
  Antioxidants & Redox Signaling
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] ER stress proteins in autoimmune and inflammatory diseases2012
- Author(s)
  D. Morito and K. Nagata
- Total Pages
  48
- Publisher
  Frontiers in Inflammation
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] Autophagy2012
- Author(s)
  D.J. Klionsky, F. C. AbdallaK, H. Abeliovich,R. T. Abraham, K. Nagata et al
- Total Pages
  100
- Publisher
  LANDES BIOSCIENCE
- Data Source
  KAKENHI-PROJECT-24227009
[Book] Cold Spring Harbor Perspectives in Biology "Protein Homeostasis"2011
- Author(s)
  K. Araki, K. Nagata, 他分担執筆
- Total Pages
  349
- Publisher
  Cold Spring Harbor Laboratory press(分担執筆)
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] Protein Folding and Quality Control in the ER Cold Spring Harbor Perspectives inBiology"Protein Homeostasis"2011
- Author(s)
  K. Araki and K. Nagata
- Publisher
  Cold SpringHarbor Laboratory press
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] Cold Spring Harbor Perspectives in Biology" Protein Homeostasis"2011
- Author(s)
  K.Araki, K.Nagata, 他分担執筆
- Total Pages
  349
- Publisher
  Cold Spring Harbor Laboratory press
- Data Source
  KAKENHI-PLANNED-19058008
[Book] Protein Folding and Quality Control in the ER, Cold Spring Harbor Perspectives in Biology "Protein Homeostasis"2011
- Author(s)
  K. Araki and K. Nagata
- Publisher
  Cold Spring Harbor Laboratory press
- Data Source
  KAKENHI-PLANNED-19058008
[Book] 医学のための細胞生物学2009
- Author(s)
  永田和宏、塩田浩平(編)
- Total Pages
  315
- Publisher
  南由堂
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] ルーイン細胞生物学2009
- Author(s)
  永田和宏, 他(訳)
- Total Pages
  681
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PLANNED-19058008
[Book] 医学のための細胞生物学2009
- Author(s)
  永田和宏、塩田浩平(編)
- Total Pages
  315
- Publisher
  南山堂
- Data Source
  KAKENHI-PLANNED-19058008
[Book] 医学のための細胞生物学2009
- Author(s)
  永田和宏、塩田浩平
- Total Pages
  315
- Publisher
  南山堂
- Data Source
  KAKENHI-PLANNED-19058008
[Book] 医学のための細胞生物学、315ページ2009
- Author(s)
  永田和宏, 塩田浩平, 編
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] ルーイン細胞生物学2008
- Author(s)
  永田和宏, 他(訳)
- Total Pages
  681
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] ルーイン細胞生物学、681ページ2008
- Author(s)
  永田和宏, 中野明彦, 米田悦啓, 須藤和夫, 室伏擴, 榎森康文, 伊藤維昭, 訳
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] 蛋白質核酸酵素増刊キーワード:蛋白質の一生2008
- Author(s)
  遠藤斗志也, 小椋光, 永田和宏, 森和俊, 田口英樹, 吉田賢右(編)
- Total Pages
  1114
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-19GS0314
[Book] ルーイン細胞生物学2008
- Author(s)
  永田和宏、中野明彦、米田悦啓、須藤和夫、室伏擴、榎森康文、伊藤維昭(訳)
- Total Pages
  681
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PLANNED-19058008
[Book] Topics in Current Chemistry : Collagen 2472005
- Author(s)
  T.KOIDE, K.NAGATA
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-16207013
[Book] Topics in Current Chemistry : Collagen 2472005
- Author(s)
  T.KOIDE, K.NAGATA
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets.2019
- Author(s)
  Munechika Sugihara, Daisuke Morito, Shiori Ainuki, Yoshinobu Hirano, Kazutoyo Ogino, Akira Kitamura, Hiromi Hirata, Kazuhiro Nagata
- Journal Title
  
  J. Cell. Biol.
  
  Volume: 218 Pages: 949-960
- DOI
  10.1083/jcb.201712120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06201, KAKENHI-PUBLICLY-17H05578, KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-16H04657
[Journal Article] A BRET-based assay reveals collagen-Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction2019
- Author(s)
  S. Ito, M. Saito, M. Yoshida, K. Takeuchi, T. Doi & K. Nagata
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294(44) Pages: 15962-15972
- DOI
  10.1074/jbc.ra119.010567
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-18K14393
[Journal Article] Roles of the endoplasmic reticulum-resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease.2019
- Author(s)
  Ito S, Nagata K.
- Journal Title
  
  J Biol. Chem.
  
  Volume: 294(6) Pages: 2133-2141
- DOI
  10.1074/jbc.tm118.002812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04002
[Journal Article] Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.2018
- Author(s)
  D. Sepulveda, D. Rojas-Rivera, DA. Rodriguez ,J. Groenendyk, A. Kohler,C. Lebeaupin,S. Ito, H. Urra, A. Carreras-Sureda, Y. Hazari, M. Vasseur-Cognet, MMU. Ali,E. Chevet,G. Campos, P. Godoy,T. Vaisar, B. Bailly-Maitre, K. Nagata,M. Michalak,J. Sierralta,C. Hetz.
- Journal Title
  
  Mol Cell.
  
  Volume: 69 Pages: 238-252
- DOI
  10.1016/j.molcel.2017.12.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Journal Article] Detection of substrate binding of a collagen-specific molecular chaperone HSP47 in solution using fluorescence correlation spectroscopy.2018
- Author(s)
  A. Kitamura, Y. Ishida, H. Kubota, CG. Pack, T. Homma, S. Ito, K. Araki, M. Kinjo, K. Nagata
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 497 Pages: 279-284
- DOI
  10.1016/j.bbrc.2018.02.069
- NAID
  120006558991
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Journal Article] Nuclear export of ubiquitinated proteins via the UBIN-POST system.2018
- Author(s)
  Hirayama S, Sugihara M, Morito D, Iemura SI, Natsume T, Murata S, Nagata K
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: in press
- DOI
  10.1073/pnas.1711017115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-16K20998, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-26000014
[Journal Article] A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis.2017
- Author(s)
  S. Ito, K. Ogawa, K. Takeuchi, M. Takagi, M. Yoshida, T. Hirokawa, S. Hirayama, K. Shin-Ya, I. Shimada, T. Doi, N. Goshima, T. Natsume, K. Nagata
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Pages: 20076-20085
- DOI
  10.1074/jbc.m117.815936
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-16K20998
[Journal Article] Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by ERdj52016
- Author(s)
  R. Ushioda, A. Miyamotod, M. Inoue, S. Watanabe, M. Okumurae, K. Maegawa, K. Uegaki, S. Fujii, Y. Fukuda, M. Umitsu, J. Takagi, K. Inaba, K. Mikoshibad, and K. Nagata
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 113(41) Pages: 6055-6063
- DOI
  10.1073/pnas.1605818113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01545, KAKENHI-PUBLICLY-15H01626, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-24227009
[Journal Article] Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF2132015
- Author(s)
  Kotani Y, Morito D, Yamazaki S, Ogino K, Kawakami K, Takashima S, Hirata H, Nagata K.
- Journal Title
  
  Scientific reports
  
  Volume: 5 Pages: 16161-16161
- DOI
  10.1038/srep16161
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07062, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K14373, KAKENHI-PUBLICLY-15H01546, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-25290008, KAKENHI-PROJECT-15H02370
[Journal Article] Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen2015
- Author(s)
  S. Ito , K. Nagata
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Pages: 437-442
- DOI
  10.1016/j.bbrc.2015.12.028
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24227009
[Journal Article] Deletion of the Collagen-specific Molecular Chaperone Hsp47 Causes Endoplasmic Reticulum Stress-mediated Apoptosis of Hepatic Stellate Cells.2015
- Author(s)
  Kawasaki K, Ushioda R, Ito S, Ikeda K, Masago Y, Nagata K
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Pages: 3639-3646
- DOI
  10.1074/jbc.m114.592139
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25840079, KAKENHI-PUBLICLY-26111521, KAKENHI-PUBLICLY-15H01545, KAKENHI-PROJECT-24227009
[Journal Article] Conformational analysis of misfolded protein aggregation by FRET and live-cell imaging techniques.2015
- Author(s)
  Akira Kitamura, Kazuhiro Nagata, Masataka Kinjo
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 16 Pages: 6076-6092
- DOI
  10.3390/ijms16036076
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-24227009
[Journal Article] Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible ?2015
- Author(s)
  Morito D, Nagata K.
- Journal Title
  
  Mol Cell.
  
  Volume: 59 Pages: 335-344
- DOI
  10.1016/j.molcel.2015.06.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07062, KAKENHI-PUBLICLY-15H01546, KAKENHI-PROJECT-24227009
[Journal Article] Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments2015
- Author(s)
  Kirstein J, Morito D, Kakihana T, Sugihara M, Minnen A, Hipp MS, Nussbaum-Krammer C, Kasturi P, Hartl FU, Nagata K, Morimoto RI.
- Journal Title
  
  EMBO J.
  
  Volume: 34 Pages: 2334-2349
- DOI
  10.15252/embj.201591711
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07062, KAKENHI-PROJECT-15K18489, KAKENHI-PUBLICLY-15H01546, KAKENHI-PROJECT-24227009
[Journal Article] Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state.2014
- Author(s)
  Daisuke Morito, Kouki Nishikawa, Jun Houseki, Akira Kitamura, Yuri Kotani, Kazumi Kiso, Masataka Kinjo, Yoshimori Fujiyoshi & Kazuhiro Nagata
- Journal Title
  
  Sci Rep.
  
  Volume: Vol. 4 Pages: 4442-4442
- DOI
  10.1038/srep04442
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J07825, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24227009, KAKENHI-PUBLICLY-25122717, KAKENHI-PROJECT-25840024
[Journal Article] Dysregulation of the proteasome increases the toxicity of ALS-linked mutant SOD1.2014
- Author(s)
  Kitamura, A., Inada, N., Kubota, H., Matsumoto, G., Kinjo, M., Morimoto, R.I., Nagata, K
- Journal Title
  
  Genes to Cells
  
  Volume: 3 Pages: 209-224
- DOI
  10.1111/gtc.12125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500434, KAKENHI-PROJECT-23770215, KAKENHI-PUBLICLY-24111554, KAKENHI-PROJECT-24227009
[Journal Article] Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia2014
- Author(s)
  Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi, T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  BMC Pulmonary Medicine
  
  Volume: 14 Pages: 48-48
- DOI
  10.1186/1471-2466-14-48
- NAID
  120005438974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-25860649
[Journal Article] Endoplasmic reticulum lectinXTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsinvariant2013
- Author(s)
  T. Fujimori, Y. Kamiya, K. Nagata, K. Kato &N. Hosokawa
- Journal Title
  
  FEBS J
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis.2013
- Author(s)
  Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi. T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  CELL STRESS & CHAPERONES
  
  Volume: 18 Pages: 581-590
- DOI
  10.1007/s12192-013-0411-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-23790913, KAKENHI-PROJECT-25860649
[Journal Article] Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis.2013
- Author(s)
  Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi. T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  Cell Stress Chaperones
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220
[Journal Article] Glycosylation-independent ERAD pathway serves as a backup system under ER stress2013
- Author(s)
  R.Ushioda, J.Hoseki & K. Nagata
- Journal Title
  
  Mol. Biol. Cell.
  
  Volume: 24(6) Pages: 3155-3163
- DOI
  10.1091/mbc.e13-03-0138
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-24121725, KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-25840079
[Journal Article] Serum heat shock protein 47 levels in patients with drug-induced lung disease.2013
- Author(s)
  Kakugawa, T., Yokota, S., Ishimatsu, Y., Hayashi, T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Y., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  Respiratory Research
  
  Volume: 14 Pages: 133-133
- DOI
  10.1186/1465-9921-14-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-25860649
[Journal Article] Dynamic Regulation of Ero1α and Peroxiredoxin 4 Localization in the Secretory Pathway2013
- Author(s)
  Taichi Kakihana, Kazutaka Araki, Stefano Vavassori, Shun-ichiro Iemura, Margherita Cortini, Claudio Fagioli, Tohru Natsume, Roberto Sitia and Kazuhiro Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 2958629594-2958629594
- DOI
  10.1074/jbc.m113.467845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02049, KAKENHI-PROJECT-12J04142, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24227009
[Journal Article] Molecular chaperone Hsp47 isessential for cartilage and endochondral boneformation2012
- Author(s)
  Y. Masago, A. Hosoya, S. Kawano, A. Nasu, J. Toguchida, K. Fujita, H. Nakamura, G. Kondoh and K. Nagata
- Journal Title
  
  J Cell Sci
  
  Volume: 125(5) Pages: 1118-1128
- DOI
  10.1242/jcs.089748
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-21240049, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592785
[Journal Article] Pirfenidone inhibits TGF-ß1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells2012
- Author(s)
  Hisatomi, K., Mukae, H., Sakamoto, N., Ishimatsu, Y., Kakugawa, T., Hara, S., Fujita, H., Nakamichi, S., Oku, H., Urata, Y., Kubota, H., Nagata, K. and Kohno, S.
- Journal Title
  
  BMC Pulm. Med.
  
  Volume: 12
- DOI
  10.1186/1471-2466-12-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220
[Journal Article] The mutation in cyclophilin B that causes hyperelastosis cutis in the American Quarter Horse does not affect peptidyl-prolyl cis-trans isomerase activity, but shows altered cyclophilin B-protein interactions and affects collagen folding.2012
- Author(s)
  Y. Ishikawa, J. A. Vranka, S. P. Boudko, E.Pokidysheva, K. Mizuno, K. Zientek, D. R.Keene, A. M. Rashmir-Raven, K. Nagata, N. J.Winand and H. P. Bachinger
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287(26) Pages: 22253-22265
- DOI
  10.1074/jbc.m111.333336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-24227009
[Journal Article] NMR and mutational identification of the collagen-binding site of the chaperone Hsp47.2012
- Author(s)
  M.Yagi-Utsumi, S.Yoshikawa, Y.Yamaguchi, Y.Nishi, E.Kurimoto, Y.Ishida, T.Homma, J.Hoseki, Y.Nishikawa, T.Koide, K.Nagata and K. Kato
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- DOI
  10.1371/journal.pone.0045930.s001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24227009
[Journal Article] Direct in vitro and in vivo evidencefor interaction between Hsp47 protein andcollagen triple helix2012
- Author(s)
  T. Ono, T. Miyazaki, Y. Ishida, M. Uehata and K. Nagata
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287(9) Pages: 6810-6818
- DOI
  10.1074/jbc.m111.280248
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Functional in vitroanalysis of ERO1 and protein-disulfide isomerase(PDI) pathway2011
- Author(s)
  K. Araki and K. Nagata
- Journal Title
  
  J. Biol Chem.
  
  Volume: 286(37) Pages: 32705-32712
- DOI
  10.1074/jbc.m111.227181
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj52011
- Author(s)
  M.Hagiwara, K.Nagata, et al
- Journal Title
  
  Mol.Cell
  
  Volume: 41 Pages: 432-444
- NAID
  120003836694
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Structural basis of an ERADpathway mediated by the ER-resident proteindisulfide reductase ERdj52011
- Author(s)
  M. Hagiwara, K. Maegawa, M. Suzuki, R. Ushioda, K. Araki, Y. Matsumoto, J. Hoseki, K. Nagata and K. Inaba
- Journal Title
  
  Molecular Cell
  
  Volume: 41(4) Pages: 432-444
- DOI
  10.1016/j.molcel.2011.01.021
- NAID
  120003836694
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-23770158
[Journal Article] Identification of RNF213as a Susceptibility Gene for Moyamoya Disease and Its Possible Role in Vascular Development.2011
- Author(s)
  Wanyang Liu, et al
- Journal Title
  
  PLos one
  
  Volume: 6(7)
- DOI
  10.1371/journal.pone.0022542
- NAID
  120003204018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10F00427, KAKENHI-PROJECT-10J05192, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-22249020, KAKENHI-PROJECT-22590817, KAKENHI-PROJECT-22710193, KAKENHI-PUBLICLY-23122520, KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-23659329
[Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010
- Author(s)
  Y. Sugiura, K. Araki, 1 S. Iemura, T. Natsume,. J. Hoseki., K. Nagata
- Journal Title
  
  J. Biol. Chem 285(10)
  
  Pages: 7135-7142
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity.2010
- Author(s)
  Y. Sugiura, K. Araki, 1 S. Iemura, T. Natsume,. J. Hoseki, K. Nagata
- Journal Title
  
  J. Biol. Chem. 285(10)
  
  Pages: 7135-7142
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] The novelthioredoxin-related transmembrane protein TMX4 has reductase activity2010
- Author(s)
  Y. Sugiura, K. Araki, S. Iemura, T. Natsume, J. Hoseki1 and K. Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 285(10) Pages: 7135-7142
- DOI
  10.1074/jbc.m109.082545
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010
- Author(s)
  Y.Sugiura, K.Nagata, et al
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 7135-7142
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Solution structure and dynamics of mouse ARMET2010
- Author(s)
  J.Hoseki, K.Nagata, et al
- Journal Title
  
  FEBS.Letters.
  
  Volume: 584 Pages: 1536-1542
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Solution structure and dynamics of mouse ARMET2010
- Author(s)
  J. Hoseki, H.Sasakawa, Y. Yamaguchi, M. Maeda, H. Kubota, K. Kato and K. Nagata
- Journal Title
  
  FEBS. Letters
  
  Volume: 584 Pages: 1536-1542
- DOI
  10.1016/j.febslet.2010.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Human 0S-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans2009
- Author(s)
  N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato, K. Nagata
- Journal Title
  
  J. Biol. Chem. 284(25)
  
  Pages: 17061-17068
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection2009
- Author(s)
  Y. Ishida, A. Yamamoto, A. Kitamura, S. R. Lamande, T. YoshimorI, F. B. John, H. Kubota, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 20
  
  Pages: 2744-2754
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans.2009
- Author(s)
  N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato, K. Nagata
- Journal Title
  
  J. Biol. Chem. 284(25)
  
  Pages: 17061-17068
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Autophagic elimination of misfolded procollagenaggregates in the endoplasmic reticulum as ameans of cell protection2009
- Author(s)
  Y.Ishida, A.Yamamoto, A.Kitamura,S.R.Lamande, T.YoshimorI, F.B.John, H.Kubota and K.Nagata
- Journal Title
  
  Mol. Biol. Cell.
  
  Volume: 20 Pages: 2744-2754
- DOI
  10.1091/mbc.e08-11-1092
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.2009
- Author(s)
  Y. Ishida, A. Yamamoto, A. Kitamura, S.R. Lamande, T. YoshimorI, F.B. John, H. Kubota, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 20
  
  Pages: 2744-2754
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Human OS-9, a lectin required forglycoprotein endoplasmic reticulum-associateddegradation, recognizes mannose-trimmedN-Glycans2009
- Author(s)
  N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato & K. Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 284(25) Pages: 17061-17068
- DOI
  10.1074/jbc.m809725200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PLANNED-20107004
[Journal Article] ERdj5 is required asa disulfide reductase for degradation of misfoldedproteins in the ER2008
- Author(s)
  R.Ushioda, J.Hoseki, K.Araki, G.Jansen, D.Y.Thomas and K.Nagata
- Journal Title
  
  Science
  
  Volume: 321(5888) Pages: 569-572
- DOI
  10.1126/science.1159293
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.2008
- Author(s)
  R. Ushioda, J. Hoseki, K. Araki, G. Jansen, D. Y. Thomas, K. Nagata
- Journal Title
  
  Science 321(5888)
  
  Pages: 569-572
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Gp78 cooperates with RMA1 in ER-associateddegradation of CFTRΔF5082008
- Author(s)
  D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D. M. Cyr, K. Tanaka, K. Iwai and K. Nagata
- Journal Title
  
  Mol. Biol. Cell.
  
  Volume: 19 Pages: 1328-1336
- DOI
  10.1091/mbc.e07-06-0601
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.2008
- Author(s)
  R. Ushioda, J. Hoseki, K. Araki, G. Jansen, D.Y. Thomas, K. Nagata
- Journal Title
  
  Science 321(5888)
  
  Pages: 569-572
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination.2008
- Author(s)
  S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D.M. Cyr, H. Kubota, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 19
  
  Pages: 899-911
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF508.2008
- Author(s)
  D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D.M. Cyr, K. Tanaka, K. Iwai, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 19
  
  Pages: 1328-1336
- Data Source
  KAKENHI-PLANNED-19058008
[Journal Article] Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP2008
- Author(s)
  N.Hosokawa, I.Wada, K.Nagasawa, T.Moriyama, K.Okawa, and K.Nagata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 283(30) Pages: 20914-20924
- DOI
  10.1074/jbc.m709336200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF5082008
- Author(s)
  D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D. M. Cyr, K. Tanaka, K. Iwai, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 19
  
  Pages: 1328-1336
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] MKKS is acentrosome-shuttling protein degraded bydisease-causing mutations via CHIP-mediatedubiquitination2008
- Author(s)
  S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D. M. Cyr, H. Kubota and K. Nagata
- Journal Title
  
  Mol. Biol. Cell.
  
  Volume: 19 Pages: 899-911
- DOI
  10.1091/mbc.e07-07-0631
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
[Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination2008
- Author(s)
  S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D. M. Cyr, H. Kubota, K. Nagata
- Journal Title
  
  Mol. Biol. Cell. 19
  
  Pages: 899-911
- Data Source
  KAKENHI-PROJECT-19GS0314
[Journal Article] Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.2006
- Author(s)
  A.Kitamura, H.Kubota, C.Pack, G.Matsumoto, S.Hirayama, Y.Takahashi, H.Kimura, M.Kinjo, R.Morimoto, K.Nagata
- Journal Title
  
  Nature Cell Biol. 8(10)
  
  Pages: 1163-1169
- NAID
  120005549596
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] Specific recognition of the collagen triple helix by chaperone HSP47 : minimal structural requirement and spatial molecular orientation.2006
- Author(s)
  Koide, T., Asada, S., Takahara, Y., Nishikawa, Y., Nagata, K., Kitagawa, K.
- Journal Title
  
  J.Biol.Chem. 281(6)
  
  Pages: 3432-3438
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.2006
- Author(s)
  Oda, Y., Okada, T., Yoshida, H., Kaufman, R.J., Nagata, K., Mori, K.
- Journal Title
  
  J.Cell Biol. 172(3)
  
  Pages: 383-393
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] Crytosolic chaperonin protects folding intermediates of Gβ from aggregation by recognizing hydrophobic β-strands2006
- Author(s)
  S.Kubota, H.Kubota, K.Nagata
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103(22)
  
  Pages: 8360-8365
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.2006
- Author(s)
  Y.Oda, T.Okada, H.Yoshida, R.J.Kaufman, K.Nagata, K.Mori
- Journal Title
  
  J. Cell Biol. 172
  
  Pages: 383-393
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] The maintenance of the endoplasmic reticulum network is regulated by p47, a cofactor of p97, through phosphorylation by cdc2 kinase.2005
- Author(s)
  Kano, F., Kondo, H., Yamamoto, A., Tanaka, A.R., Hosokawa, N., Nagata, K., Murata, M.
- Journal Title
  
  Genes Cells 10(4)
  
  Pages: 333-344
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage.2005
- Author(s)
  Naitoh M, Kubota H, Ikeda M, Tanaka T, Shirane H, Suzuki S, Nagata K.
- Journal Title
  
  Genes. Cells. 10(11)
  
  Pages: 1081-91
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591874
[Journal Article] ene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage.2005
- Author(s)
  NAITOH, H.KUBOTA, M.IKEDA, T.TANAKA, H.SIRANE, S.SUZUKI., K.NAGATA.
- Journal Title
  
  Genes Cells 10(10)
  
  Pages: 1081-1091
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] pecific recognition of the collagen triple helix by chaperone HSP47.Minimal structural requirement and spatial molecular orientation.2005
- Author(s)
  T, KOIDE, S.ASADA, Y.TAKAHARA, Y.NISHIKAWA, K.NAGATA., K.KITAGAWA.
- Journal Title
  
  J.Biol.Chem 281(6)
  
  Pages: 3432-3438
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] 2005, Retropharyngeal lymph node metastasis from oral cancer : A report of two patients2005
- Author(s)
  M.Nishida, S.Yasuda, K.Murakami, I.Yamamura, Y.Nagata, T.Iizuka
- Journal Title
  
  J Oral Maxillofac Surg 63(3)
  
  Pages: 410-412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle-dependent reformation of the ER network.2005
- Author(s)
  KANO, H.KONDO, A.YAMAMOTO, Y.KANEKO, K.UCHIYAMA, N.HOSOKAWA, K.NAGATA, M.MURATA.
- Journal Title
  
  Genes Cells 10(10)
  
  Pages: 989-999
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Proinsulin lacking the A7-B7 disulfide bond, Ins2 Akita, tends to aggregate due to the exposed hydrophobic surface.2005
- Author(s)
  Yoshinaga T, Nakatome K, Nozaki J, Naitoh M, Hoseki J. Kubota H, Nagata K, Koizumi A.
- Journal Title
  
  Biological Chemistry. 386(11)
  
  Pages: 1077-85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591874
[Journal Article] The maintenance of the endoplasmic reticulum network is regulated by p47, a cofactor of p97, through phosphorylation by cdc2 kinase.2005
- Author(s)
  KANO, H.KONDO, A.YAMAMOTO, AR.TANAKA, N.HOSOKAWA, K.NAGATA., M.MURATA.
- Journal Title
  
  Genes Cells 10(4)
  
  Pages: 333-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy.2004
- Author(s)
  OHASHI, H.ABE, T.TAKAHASHI, Y.YAMAMOTO, M.TAKEUCHI, H.ARAI, K.NAGATA, T.KITA, H.OKAMOTO, H.YAMAMOTO, T.DOI.
- Journal Title
  
  J.Biol.Chem. 279(19)
  
  Pages: 19816-19823
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Accumulation of type IV collagen in dilated endoplasmic reticulum leads to apoptosis HSP47-Knockout mouse embryos2004
- Author(s)
  K.NAGATA et al.
- Journal Title
  
  J.Cell.Sci. 117
  
  Pages: 5913-5922
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] CHOP induces death by promoting protein synthesis and oxidation in thestressed endoplasmic reticulum2004
- Author(s)
  S.J.MARCINIAK, C.Y.YUN, S.OYADOMARI, I.NOVOA, Y.ZHANG, R.JUNGREIS, K.NAGATA, H.P.HARDING., D.RON.
- Journal Title
  
  Genes Develop. 18(24)
  
  Pages: 3066-77
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy2004
- Author(s)
  K.NAGATA et al.
- Journal Title
  
  J.Biol.Chem 279・19
  
  Pages: 19816-19823
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Characterization of multiple members of the HSP70-family in platytish culture cells2004
- Author(s)
  K.NAGATA et al.
- Journal Title
  
  Gene 336
  
  Pages: 207-218
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Accumulation of type IV collagen in dilated endoplasmic reticulum leads to apoptosis HSP47-knockout mouse embryos through the induction of CHOP.2004
- Author(s)
  T.MARUTANI, A.YAMAMOTO, N.NAGAI, H.KUBOTA, K.NAGATA
- Journal Title
  
  J.Cell.Sci. 117
  
  Pages: 5913-5922
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] Insufficient folding of type IV collagen nad formation of abnormal basement membrane-like structure in embryoid bodies derived from HSP47-null ES cells.2004
- Author(s)
  MATSUOKA, H.KUBOTA, E.ADACHI, N.NAGAI, T.MARUTANI, N.HOSOKAWA., K.NAGATA.
- Journal Title
  
  Mol.Biol.Cell. 15
  
  Pages: 4467-4475
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] haracterization of multiple members of the HSP70 family in platyfishculture cells : molecular evolution of stress protein HSP70 in vertebrates.2004
- Author(s)
  YAMASHITA, K.HIRAYOSHI., K.NAGATA.
- Journal Title
  
  Gene 336
  
  Pages: 207-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] ccumulation of type IV collagen in dilated endoplasmic reticulum leads to apoptosis HSP47-knockout mouse embryos through the induction of CHOP.2004
- Author(s)
  MARUTANI, A.YAMAMOTO, N.NAGAI, H.KUBOTA., K.NAGATA.
- Journal Title
  
  J.Cell.Sci. 117
  
  Pages: 5913-5922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.2004
- Author(s)
  NOZAKI, H.KUBOTA, H.YOSHIDA, M.NAITOH, J.GOJO, T.YOSHINAGA, K.MORI, A.KOIZUMI., K.NAGATA.
- Journal Title
  
  Genes Cells 9
  
  Pages: 261-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] Insufficient folding of type IV collagen and formation of abnormal basement membrane-like structure in embryoid bodies derived from HSP47-null ES cells.2004
- Author(s)
  Y.MATSUOKA, H.KUBOTA, E.ADACHI, N.NAGAI, T.MARUTANI, N.HOSOKAWA, K.NAGATA
- Journal Title
  
  Mol.Biol.Cell. 15
  
  Pages: 4467-4475
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] The ER stress response in stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells2004
- Author(s)
  K.NAGATA et al.
- Journal Title
  
  Genes Cells 9
  
  Pages: 261-270
- Data Source
  KAKENHI-PROJECT-16591992
[Journal Article] EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin.2003
- Author(s)
  Y. ODA, N. HOSOKAWA, I. WADA & K. NAGATA
- Journal Title
  
  Science 299(5611)
  
  Pages: 1394-1397
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin.2003
- Author(s)
  Y. ODA, N. HOSOKAWA, I. WADA & K. NAGATA
- Journal Title
  
  Science 299 (5611)
  
  Pages: 1394-1397
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13053101
[Journal Article] HSP47 as a collagen-specific molecular chaperone : function and expression in normal mouse development.2003
- Author(s)
  K. Nagata
- Journal Title
  
  Seminars in Cell and Developmental Biology 14
  
  Pages: 275-282
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14037230
[Journal Article] HSP47 as a collagen-specific molecular chaperone : function and expression in normal mouse development.2003
- Author(s)
  K. Nagata
- Journal Title
  
  Seminars In Cell and Developmental Biology 14
  
  Pages: 275-282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Patent] 細胞内の異常物質蓄積を伴う疾患の治療薬、バイオマーカー、診断薬、並びに、スクリーニング方法2015
- Inventor(s)
  永田和宏、山本洋平
- Industrial Property Rights Holder
  京都産業大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-174597
- Filing Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-24227009
[Patent] 2-ヒドロキシベンズアルデヒド化合物、これを含有するコラーゲン細胞外分泌阻害剤及び医薬品組成物2012
- Inventor(s)
  夏目徹、永田和宏、伊藤進也、土井隆行、吉田将人
- Industrial Property Rights Holder
  夏目徹、永田和宏、伊藤進也、土井隆行、吉田将人
- Industrial Property Number
  2012-163835
- Filing Date
  2012-07-24
- Data Source
  KAKENHI-PROJECT-19GS0314
[Patent] カルシウムポンプ制御物質のスクリーニング方法、メラニン色素合成阻害物質のスクリーニング方法、ベクター、並びに、細胞2012
- Inventor(s)
  潮田亮、永田和宏
- Industrial Property Rights Holder
  潮田亮、永田和宏
- Industrial Property Number
  2012-176344
- Filing Date
  2012-08-08
- Data Source
  KAKENHI-PROJECT-19GS0314
[Patent] モヤモヤ病関連遺伝子及びその利用2010
- Inventor(s)
  小泉昭夫、永田和宏、森戸大介、高島成二、山崎悟、橋本信夫、松浦範夫、人見敏明
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2010-10-22
- Overseas
- Data Source
  KAKENHI-PROJECT-22249020
[Presentation] Maintenaice of ER homeostasis through disulfide reductase2019
- Author(s)
  Ryo Ushioda, Kaiku Uegaki and Kazuhiro Nagata
- Organizer
  Gordon Research Conference"2019 Stress Proteins in Growth, Development and Desease"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Presentation] Protein folding and misfolding in the Endoplasmic Reticulum2019
- Author(s)
  Kazuhiro Nagata
- Organizer
  EMBO workshop “Protein quality control: From mechanisms to disease”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Presentation] Nascent polypeptide as a souse of reductive power in the ER2018
- Author(s)
  Kazuhiro Nagata
- Organizer
  International Symposium "Proteins:from the Cradle to the Grave"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Presentation] Role of ER J protein for the maintenance of ER homeostasis2018
- Author(s)
  Kazuhiro Nagata
- Organizer
  International workshop of CSSI
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Presentation] ERdj5 as a master regulator of the ER homeostasis: crosstalk of Ca2+ and redox homeostasis2018
- Author(s)
  Kazuhiro Nagata
- Organizer
  FASEB Meeting "Protein Research Conferences"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Presentation] Redox-mediated regulation of ER homeostasis2018
- Author(s)
  Kazuhiro Nagata
- Organizer
  Cold Spring Harbor Meeting “Protein Homeostasis in Health and Disease”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04002
[Presentation] Protein Quality Control in the Endoplasmic Reticulum2017
- Author(s)
  Kazuhiro Nagata
- Organizer
  Protein Society Annual Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227009
[Presentation] Crosstalk among protein, redox and calcium homeostasis in the ER2015
- Author(s)
  Kazuhio Nagata
- Organizer
  JSCB Presympojium”Cutting-edge of stress-response and protein homeostasis”
- Place of Presentation
  Ｎａｒａ（Ｊａｐａｎ）
- Year and Date
  2015-06-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227009
[Presentation] ERdj5, an ER-resident reductase, regulates the activity of SERCA2, a calcium ATPase, in a [Ca2+]-dependent manner2015
- Author(s)
  Kazuhio Nagata
- Organizer
  EMBO conference”Molecular chaperones : From molecules to cells and misfolding deseases”
- Place of Presentation
  Crete(Greece)
- Year and Date
  2015-05-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227009
[Presentation] Regulation of collagen synthesis by Hsp47 and P4H in combination with specific inhibitors2013
- Author(s)
  K.Nagata
- Organizer
  Gordon Research Conferences”Collagen”
- Place of Presentation
  New London(USA)
- Year and Date
  2013-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-24227009
[Presentation] Two distinct ERAD pathways formisfolded glycoproteins and non-glycoproteins SFB5942012
- Author(s)
  K. Nagata
- Organizer
  3^<rd>International Symposium on Molecular Machines in Protein Folding and Protein Transport
- Place of Presentation
  Munich(Germany)
- Year and Date
  2012-07-24
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Two distinct ERAD pathways for misfolded glycoproteins and non‐glycoproteins2012
- Author(s)
  Kazuhiro Nagata
- Organizer
  SFB594 3rd International Symposium on Molecular Machines in Protein Folding and Protein Transport
- Place of Presentation
  Munich(Germany)
- Invited
- Data Source
  KAKENHI-PROJECT-24227009
[Presentation] Regulation and structure of a novelAAA+/ubiquitin ligase protein2012
- Author(s)
  K. Nagata
- Organizer
  mysterin EMBO/EMBL Symposium"QualityControl-From Molesules to Organelles"
- Place of Presentation
  Heiderberg(Germany)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Regulation of redox homeostasisin the ER2012
- Author(s)
  K. Nagata
- Organizer
  Cold Spring Harbor Meeting,Molecular Chaperones & Stress Responses
- Place of Presentation
  Cold Spring Harbor(USA)
- Year and Date
  2012-05-02
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] もやもや病感受性遺伝子であるATPase/ユビキチンリガーゼMysterinの生化学的検討2012
- Author(s)
  人見敏明、森戸大介、劉万洋、小林果、原田浩二、永田和宏、小泉昭夫
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-22249020
[Presentation] Protein quality control and proteostasis in the ER2011
- Author(s)
  K.Nagata
- Organizer
  Cold Spring Harbor Asia Conference
- Place of Presentation
  Suzhou (China)(招待講演)
- Year and Date
  2011-09-29
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Two distinct ERAD pathways contribute for maintaining the protein homeostasis in the EREMBO Conference2011
- Author(s)
  K. Nagata
- Organizer
  The biology of Molecular Chaperones
- Place of Presentation
  Grundlsee(Austria)
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Regulation of redoxhomeostasis in the ER2011
- Author(s)
  K. Nagata and R. Sitia
- Organizer
  Conference on QualityControl: Folding and Degradation of Proteins inthe Endoplasmic Reticulum
- Place of Presentation
  Ascona(Switzerland)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Protein quality control andproteostasis in the ER2011
- Author(s)
  K. Nagata
- Organizer
  Cold Spring Harbor Asia Conference,"Protein Homeostasis in Health &Disease"
- Place of Presentation
  Suzhou(China)
- Year and Date
  2011-09-29
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Regulation of redox homeostasis in the ER2011
- Author(s)
  K. Nagata and R. Sitia
- Organizer
  Conference on Quality Control: Folding and Degradation of Proteins in the Endoplasmic Reticulum
- Place of Presentation
  Ascona(Switzerland)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Protein quality control in the ER and the nucleus2011
- Author(s)
  K. Nagata
- Organizer
  Gordon Research Conference
- Place of Presentation
  Lucca (Italy)(招待講演)
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Protein quality control and proteostasis in the ER2011
- Author(s)
  K. Nagata
- Organizer
  Cold Spring Harbor Asia Conference, "Protein Homeostasis in Health & Disease"
- Place of Presentation
  Suzhou(China)
- Year and Date
  2011-09-29
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Two distinct ERAD pathways contribute for maintaining the protein homeostasis in the ER2011
- Author(s)
  K. Nagata
- Organizer
  EMBO Conference "The biology of Molecular Chaperones"
- Place of Presentation
  Grundlsee(Austria)
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] 新規巨大ATP アーゼ/ ユビキチンリガーゼMysterin は血管新生を制御し,モヤモヤ病(ウイリス動脈輪閉塞症)に関与する2010
- Author(s)
  森戸大介、劉万洋、山崎悟、人見敏明、小林果、松浦範夫、箸方宏州、原田浩二、高島成二、宮本享、橋本信夫、小泉昭夫、永田和宏
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-22249020
[Presentation] Regulation in the electron transfer cascade among the oxidoreductases in the endoplasmic reticulum2010
- Author(s)
  K. Nagata
- Organizer
  The 3^<rd> International Symposium on Protein Community
- Place of Presentation
  Nara
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Quality control & Redox regulatory network2010
- Author(s)
  K. Araki,R. Ushioda,J. Hoseki and K.Nagata
- Organizer
  Gordon Research Conference
- Place of Presentation
  Lucca (Italy)
- Year and Date
  2010-05-11
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Quality control & Redox regulatory network2010
- Author(s)
  K. Araki, R. Ushioda, J. Hoseki and K. Nagata
- Organizer
  Gordon Research Conference
- Place of Presentation
  Lucca (Italy)
- Year and Date
  2010-05-11
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Regulation in the electron transfer cascade among the oxidoreductases in the endoplasmic reticulum2010
- Author(s)
  K. Nagata
- Organizer
  The 3^<rd> International Symposium on Protein Community
- Place of Presentation
  Nara
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Regulation in the electron transfer cascade among the oxidor eductases in the endoplasmic reticulum2010
- Author(s)
  Kazuhiro Nagata
- Organizer
  The 3^<rd> International Symposium on Protein Community
- Place of Presentation
  Nara (Japan)
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Revisiting of collagen-specificmolecular chaperone Hsp47:Fate of procollagenwith or without Hsp472009
- Author(s)
  K. Nagata
- Organizer
  Yokosuka Science Festa 2009 8th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Opening Lecture, Shonan
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Quality control of misfolded proteins in the endoplasmic reticulum2009
- Author(s)
  Kazuhiro Nagata
- Organizer
  21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai(China)
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Revisiting of collagen-specific molecular chaperone Hsp47:Fate of procollagen with or without Hsp472009
- Author(s)
  K. Nagata
- Organizer
  Yokosuka Science Festa 2009 8th Pan-Pacific Connective Tissue Societies Symposium. Opening Lecture
- Place of Presentation
  Shonan
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Two distinct ERAD pathways for misfolded glycoprotein and non-glycoprotein2009
- Author(s)
  K. Nagata
- Organizer
  4^<th> International Congress on Stress Responses in Biology and Medicine.Plenary lecture
- Place of Presentation
  Sapporo
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Quality control of misfoldedproteins in the endoplasmic reticulum2009
- Author(s)
  K. Nagata
- Organizer
  21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai(China)
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Quality control of misfolded proteins in the endoplasmic reticulum.2009
- Author(s)
  Kazuhiro Nagata
- Organizer
  21th IUBMB International Congress and 12^th FAOBMB Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai (China)
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Two distinct ERAD pathways for misfolded glycoprotein and non-glycoprotein2009
- Author(s)
  K. Nagata
- Organizer
  4^<th> International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Plenary lecture, Sapporo
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Quality control of misfolded proteins in the endoplasmic reticulum2009
- Author(s)
  K. Nagata
- Organizer
  21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai(China)
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Quality control of misfolded proteins in the endoplasmic reticulum.2009
- Author(s)
  Kazuhiro Nagata
- Organizer
  21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai(China)
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47:Alternative degradation pathway of misfolded procollagen in the ER;ERAD and autophagy2008
- Author(s)
  K. Nagata, Y. Masago, Y. Ishida
- Organizer
  Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold Spring Harbor(USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] ケロイドにおける弾性線維欠損のメカニズム2008
- Author(s)
  石河利広、内藤素子、久保田広志、池田実香、吉川勝宇、山脇聖子、永田和宏、中邨智之、鈴木茂彦
- Organizer
  第40回結合組織学会
- Place of Presentation
  東京
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19592073
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : alternative degradation pathway of misfolded procollagen in the ER ; ERAD and autophagy2008
- Author(s)
  K. NAGATA
- Organizer
  Cold Sring Harbor Meeting
- Place of Presentation
  Cold Sring Harbor(USA)
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47:Alternative degradation pathway of misfolded procollagen in the ER2008
- Author(s)
  Kazuhiro Nagata, Yusaku Masago, Yoshihito Ishida
- Organizer
  ERAD and autophagy Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold Spring Harbor(USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : Alternative degradation pathway of misfolded procollagen in the ER ; ERAD and autophagy2008
- Author(s)
  Kazuhiro Nagata, Yusaku Masago, Yoshihito Ishida
- Organizer
  Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold Spring Harbor (USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : Alternative degradation pathway of misfolded procollagen in the ER ; ERAD and autophagy2008
- Author(s)
  Kazuhiro Nagata, et al.
- Organizer
  Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold Spring Harbor (USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] 大腸菌多機能プロテアーゼ/シャペロンHtrA/DegPのヒトホモローグの一つHtrA1の発現はケロイドの病期と予後に相関する2008
- Author(s)
  内藤素子、久保田広志、石河利広、吉川勝宇、山脇聖子、鈴木茂彦、永田和宏
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-19592073
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47: Alternative degradation pathway of misfolded procollagen in the ER; ERAD and autophagy2008
- Author(s)
  Kazuhiro Nagata
- Organizer
  Cold Spring Harbor Meeting
- Place of Presentation
  Cold Spring Harbor (USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : Alternative degradation pathway of misfolded procollagen in the ER : ERAD and autophagy2008
- Author(s)
  Kazuhiro Nagata, et al.
- Organizer
  Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold Spring Harbor(USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Revisiting of collagen-specific molecular chaperone HSP47:Alternative degradation pathway of misfolded procollagen in the ER;ERAD andautophagy2008
- Author(s)
  K. Nagata,Y. Masago, Y. Ishida
- Organizer
  Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold SpringHarbor(USA)
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Thiol reductase ERdj5 accelerates the ER-associated degradation by cleaving intermolecular disulfide bonds of misfolded proteis2007
- Author(s)
  K.Nagata
- Organizer
  Gordon Research Conference, Stress Proteins in Growth
- Place of Presentation
  Development & Desease, Oxford(UK)
- Year and Date
  2007-08-21
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Collagen-specific molecular chaperone HSP472007
- Author(s)
  K.Nagata
- Organizer
  7th Pan Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Cairns(Australia)
- Year and Date
  2007-10-30
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Collagen-specific molecular chaperone HSP472007
- Author(s)
  K.Nagata
- Organizer
  7th Pan Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Cairns(Australia)
- Year and Date
  2007-10-30
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] A novel thiol reductase ERdj5 accelerates ER-associated degradation by cleaving the intermolecular disulfide bonds of misfolded proteins2007
- Author(s)
  K. Nagata
- Organizer
  FASEB Summer Research Conference, Proteins Folding in the Cell
- Place of Presentation
  Palm Springs(USA)
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] Thiol reductase ERdj5 accelerates the ER-associated degradation by cleaving intermolecular disulfide bonds of misfolded proteis2007
- Author(s)
  K.Nagata
- Organizer
  Gordon Research Conference, Stress Proteins in Growth,Development & Desease
- Place of Presentation
  Oxford(UK)
- Year and Date
  2007-08-21
- Data Source
  KAKENHI-PLANNED-19058008
[Presentation] A novel thiol reductase ERdj5 accelerates ER-associated degradation by cleaving the intermolecular disulfide bonds of misfolded proteins2007
- Author(s)
  K. Nagata
- Organizer
  FASEB Summer Research Conference, Proteins Folding in the Cell
- Place of Presentation
  Palm Springs(USA)
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-19GS0314
[Presentation] Cytosolic Chaperonin CCT : substrate recognition and the role in protein quality control.2006
- Author(s)
  K. Nagata
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto (Japan)
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Cytosolic chaperonin CCT/TRiC prevents the aggregation of β-sheet-containing proteins2006
- Author(s)
  K. Nagata
- Organizer
  2006 FASEB Summer Research Conferences Protein FoIding in the Cell
- Place of Presentation
  Vermont (USA)
- Year and Date
  2006-08-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Cytosolic Chaperonin CCT : substrate recognition and the role in protein quality control.2006
- Author(s)
  K. Nagata
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto(Japan)
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Cytosolic chaperonin CCT/TRiC prevents the aggregation of β-sheet-containing proteins2006
- Author(s)
  K. Nagata
- Organizer
  2006 FASEB Summer Research Conferences Protein Folding in the Cell
- Place of Presentation
  Vermont(USA)
- Year and Date
  2006-08-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Several components involved in ER-associated degradation of misfolded glycoproteins2005
- Author(s)
  K. Nagata
- Organizer
  International Symposium on Life of Proteins
- Place of Presentation
  Awaji (Japan)
- Year and Date
  2005-11-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Different mechanisms of the acceleration of ER-associated degradationby EDEM family proteins.2005
- Author(s)
  K. Nagata
- Organizer
  EMBO-FEBS WORKSHOP on Biology of Molecular Chaperones
- Place of Presentation
  Zakopane (Poland)
- Year and Date
  2005-05-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER-associated degradation of misfolded proteins by EDEM and EDEM familyproteins.2005
- Author(s)
  K. Nagata
- Organizer
  Second International Congress on stress Responses in Biology and Medicine
- Place of Presentation
  Tomar(Portugal)
- Year and Date
  2005-09-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Different mechanisms of the acceleration of ER-associated degradation by EDEM family proteins.2005
- Author(s)
  K. Nagata
- Organizer
  EMBO-FEBS WORKSHOP on Biology of Molecular Chaperones
- Place of Presentation
  Zakopane (Poland)
- Year and Date
  2005-05-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER-associated degradation of misfolded proteins by EDEM and EDEM familyproteins.2005
- Author(s)
  K. Nagata
- Organizer
  Second International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Tomar (Portugal)
- Year and Date
  2005-09-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER stress and ER-Associated degradation of misfolded proteins2005
- Author(s)
  K. Nagata
- Organizer
  The 18th Naitoh Conference
- Place of Presentation
  Shonan (Japan)
- Year and Date
  2005-10-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER stress and ER-Associated degradation of misfolded proteins2005
- Author(s)
  K. Nagata
- Organizer
  The 18th Naitoh Conference
- Place of Presentation
  Shonan(Japan)
- Year and Date
  2005-10-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Role of collagen-specific molecular chaperone HSP47 in the correct foldingand fibrilformation of procollagens ; lessons from mice and cells disrupted with hsp47 gene.2005
- Author(s)
  K. Nagata
- Organizer
  Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Hawaii (USA)
- Year and Date
  2005-12-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Role of collagen-specific molecular chaperone HSP47 in the correct folding and fibril formation of procollagens ; lessons from mice and cells disrupted with hsp47 gene.2005
- Author(s)
  K. Nagata
- Organizer
  Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Hawaii (USA)
- Year and Date
  2005-12-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Substrate recognition by HSP47, a collagen-specific molecular chaperone, as amember of serpin superfamily.2005
- Author(s)
  K. Nagata
- Organizer
  The 4th International Symposium on Serpin
- Place of Presentation
  Cairns (Australia)
- Year and Date
  2005-06-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Substrate recognition by HSP47, a colagen-specific molecular chaperone, as amember of serpin superfamily.2005
- Author(s)
  K. Nagata
- Organizer
  The 4th International Symposium on Serpin
- Place of Presentation
  Cairns(Australia)
- Year and Date
  2005-06-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER-associate degradation : EDEM, soluble EDEM and more. . .2004
- Author(s)
  K. Nagata
- Organizer
  The 1st Pacific-Rim International Conference on Protein Science
- Place of Presentation
  Yokohama(Japan)
- Year and Date
  2004-04-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Is EDEM a lectin-like chaperone involved in ERAD? --EDEM, soluble EDEM and more...2004
- Author(s)
  K. Nagata
- Organizer
  Cold Spring Harbor Meeting" Molecular Chaperones and the Heat Shock Response" Cold Spring Harbor
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER-associate degradation EDEM, soluble EDEM and more...2004
- Author(s)
  K. Nagata
- Organizer
  The 1st Pacific-Rim International Conference on Protein Science
- Place of Presentation
  Yokohama (Japan)
- Year and Date
  2004-04-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Is EDEM a lectin-like chaperone involved in ERAD? -EDEM, soluble EDEM and more…2004
- Author(s)
  K. Nagata
- Organizer
  Cold Spring Harbor Meeting"Molecular Chaperones and the Heat Shock Response"
- Place of Presentation
  Cold Spring Harbor (USA)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] HSP47 : as a key molecule for molecular maturation of procollagen.2003
- Author(s)
  K. Nagata
- Organizer
  5th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Ube (Japan)
- Year and Date
  2003-06-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER-associated degradation : Possible function of EDEM.2003
- Author(s)
  K. Nagata
- Organizer
  10th Congress of the Federation of Asian and Oceanic Biochemists and Molecular Biologists
- Place of Presentation
  Bangalore(lndia)
- Year and Date
  2003-12-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] HSP47 : as a key molecule for molecular maturation of procollagen.2003
- Author(s)
  K. Nagata
- Organizer
  5th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Ube
- Year and Date
  2003-06-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] HSP47 is essential for the molecular maturation of collagens and the formation of basement membranes.2003
- Author(s)
  K. Nagata
- Organizer
  Gordon Research Conferences(Callagen)
- Place of Presentation
  New London (USA)
- Year and Date
  2003-07-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] EDEM cooperates with calnexin in the ER associated degradation of unfolded proteins.2003
- Author(s)
  K. Nagata
- Organizer
  EURESCO Conferences
- Place of Presentation
  Tomar(Portugal)
- Year and Date
  2003-09-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] ER-associated degradation : Possible function of EDEM.2003
- Author(s)
  K. Nagata
- Organizer
  10th Congress of the Federation of Asian and Oceanic Biochemists and Molecular Biologists
- Place of Presentation
  Bangalore(India)
- Year and Date
  2003-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Possible functions od EDEM in the ERAD of terminally misfolded proteins.2003
- Author(s)
  K. Nagata
- Organizer
  1st International Congress on stress Responses in Biology and Medicine
- Place of Presentation
  Quebec(Canada)
- Year and Date
  2003-09-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Quality Control Mechanism of the Unfolded Proteins in ER.2003
- Author(s)
  K. Nagata
- Organizer
  The 7th International Congress(Genes, Gene Families and Isozymes)
- Place of Presentation
  Berlin (Germany)
- Year and Date
  2003-07-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] EDEM cooperates with calnexin in the ER associated degradation of unfolded proteins2003
- Author(s)
  K. Nagata
- Organizer
  EURESCO Conferences
- Place of Presentation
  Tomar(Portugal)
- Year and Date
  2003-09-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Possible functions od EDEM in the ERAD of terminally misfolded proteins.2003
- Author(s)
  K. Nagata
- Organizer
  1st International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Quebec (Canada)
- Year and Date
  2003-09-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Quality Control Mechanism of the Unfolded Proteins in ER2003
- Author(s)
  K. Nagata
- Organizer
  The 7th International Congress(Genes, Gene Families and lsozymes)
- Place of Presentation
  Berlin (Germany)
- Year and Date
  2003-07-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] HSP47 is essential for the molecular maturation of collagens and the formation of basement membranes.2003
- Author(s)
  K. Nagata
- Organizer
  Gordon Research Conferences(Collagen)
- Place of Presentation
  New London(USA)
- Year and Date
  2003-07-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230
[Presentation] Quality control of the nascent proteins in the endoplasmic reticulum.2002
- Author(s)
  K. Nagata
- Organizer
  The 4th APOCB for Cell Biology Congress
- Place of Presentation
  Taipei (Taiwan)
- Year and Date
  2002-11-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037230

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# of Collaborated Products: 1 results
161. LIU Wangyang

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
162. 北風政史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagata Kazuhiro 永田 和宏

NAGATA Kazuhiro 永田 和宏

永田 和広 ナガタ カズヒロ

永田 和弘 ナガタ カズヒロ

長田 和宏 ナガタ カズヒロ

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Novel mechanism of the removal of reactive oxygen species in the ERPrincipal Investigator

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Mechanism of the maintenance of ER homeostasis by redox regulationPrincipal Investigator

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Quality control mechanism of misfolded proteins in the ERPrincipal Investigator

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productive foldingと品質管理によるタンパク質の動態制御Principal Investigator

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Quality control mechanism of misfolded proteinsPrincipal Investigator

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Nagata Kazuhiro 永田和宏

NAGATA Kazuhiro 永田和宏

永田和広ナガタカズヒロ

永田和弘ナガタカズヒロ

長田和宏ナガタカズヒロ