YASUDA Kunihiko 安田邦彦

… Alternative Names

安田邦彦ヤスダクニヒコ

KUNIHIKO Yasuda 安田邦彦

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Researcher Number	50278446
Other IDs
External Links
Affiliation (Current)	2022: 帝京大学, 公私立大学の部局等, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 帝京大学, 公私立大学の部局等, 教授 2017: 東海学院大学, 健康福祉学部, 准教授(移行) 2016: 東海学院大学, 健康福祉学部, 講師 2015: 東海学院大学, 公私立大学の部局等, 講師 2014: 長崎大学, 医歯薬学総合研究科(医学系), 助教 … More 2013: 長崎大学, 医歯薬学総合研究科, 助教 2012: 長崎大学, 医歯(薬)学総合研究科, 助教 2010 – 2011: 長崎大学, 大学院・医歯薬学総合研究科, 助教 1997 – 1998: 京都薬科大学, 薬学部, 助手 1995: 京都薬科大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Neurochemistry/Neuropharmacology / General medical chemistry
Keywords	Principal Investigator HDAC6 / 分子シャペロン / オートファジー / mTOR / アセチル化修飾 / 老化 / アセチル化 / インスリンシグナル / 神経老化 / Mdm20 … More / Akt / ｍTORC2 / Rictor / アクチンリモデリング / ホメオスタシス / 老化制御因子 / mTORシグナル / 細胞老化 / マイクロRNA / 精子形成 / Akt/PKB / シャペロン介在性オートファジー / 健康長寿 / 老化シグナル / タンパク質の品質管理 … More Except Principal Investigator HSP105 / ストレス蛋白質 / 熱ショック蛋白質 / cDNAクローニング / FM3A細胞 / 老化 / 寿命 / 脳 / 神経可塑性 / シグナル伝達 / 蛋白質凝集 / アセチル化 / 神経 / 可塑性 / オートファジー / 微小管 / 蛋白凝集 / HSP105遺伝子 / アポトーシス / 胎児発生 / マウス / Stress protein / HSP105 gene / Apoptosis / Embryo developement / Heat shock protein / Mouse Less

アセチル化修飾によるmTORシグナルの陰陽制御機構と老化制御Principal Investigator
- Principal Investigator
  
  安田邦彦
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Teikyo University
Regulation of neuronal ageing through the mTOR signaling by acetylationPrincipal Investigator
- Principal Investigator
  
  YASUDA KUNIHIKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokai Gakuin University
  Nagasaki University
Positive and negative regulations of cytoskeletal dynamism and neuronal lifespan
- Principal Investigator
  
  MORI Nozomu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagasaki University
Roles of stress protein hsp105 during mouse embryo development.
- Principal Investigator
  
  HATAYAMA Takumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Pharmaceutical University
高分子量ストレス蛋白質の構造と機能
- Principal Investigator
  
  HATAYAMA Takumi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University

All 2020 2017 2015 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Mdm20 modulates action remodeling through the mTORC2 pathway via its effect on Rictor expression2015
- Author(s)
  Kunihiko Yasuda, Mayumi Takahashi, Nozomu Mori
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0142943
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430072, KAKENHI-PROJECT-15K14352
[Journal Article] Mdm20 stimulates PolyQ aggregation via inhibiting autophagy through Akt-Ser473 phosphorylation2013
- Author(s)
  Yasuda K, Ohyama K, Onga K, Kakizuka A, Mori N
- Journal Title
  
  PLoS One
  
  Volume: 16;8(12)
- NAID
  120006986747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121
[Journal Article] Mdm20 Stimulates PolyQ Aggregation via Inhibiting Autophagy Through Akt-Ser473 Phosphorylation.2013
- Author(s)
  Yasuda K, Ohyama K, Onga K, Kakizuka A, Mori N
- Journal Title
  
  PLoS One.
  
  Volume: 16;8(12):e82523 Pages: 1-15
- DOI
  10.1371/journal.pone.0082523
- NAID
  120006986747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121, KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-24650200
[Journal Article] Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain: Implications for co-operative versus non-co-operative actions of Mdm20 and Nat52012
- Author(s)
  Ohyama K, Yasuda K, Onga K, Kakizuka A, Mori N
- Journal Title
  
  Gene Expression Patterns
  
  Volume: 12 Pages: 36-45
- DOI
  10.1016/j.gep.2011.11.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121, KAKENHI-PROJECT-24650200
[Journal Article] Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain : Implications for co-operative versus non-co-operative actions of Mdm20 and Nat52012
- Author(s)
  Ohyama K, Yasuda K, Onga K, Kakizuka A, Mori N
- Journal Title
  
  Gene Expr Patterns
  
  Volume: 12 Pages: 36-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121
[Journal Article] Characterization of stress sensitivity and chaperone activity of Hsp105 in mammalian cells2011
- Author(s)
  Yamagishi N, Yokota M, Yasuda K, Saito Y, Nagata K, Hatayama T
- Journal Title
  
  Biochem Biophys Kes Commun
  
  Volume: 409(1) Pages: 90-95
- DOI
  10.1016/j.bbrc.2011.04.114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121
[Journal Article] Maintaining ATP levels via the suppression of PERK-mediated rRNA synthesis at ER stress2010
- Author(s)
  Okamoto A, Koike M, Yasuda K, Kakizuka A
- Journal Title
  
  Biochem.Biophys.Res.Commun
  
  Volume: 394(1) Pages: 42-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] アセチル化修飾による老化シグナルの統括的制御機構の構築2020
- Author(s)
  安田　邦彦
- Organizer
  第3回帝京大学研究交流シンポジウム
- Data Source
  KAKENHI-PROJECT-19K11726
[Presentation] HDAC6によるHSP105との結合を介したHSP70の機能制御2017
- Author(s)
  安田邦彦、廣瀬翔、斎藤洋平、森望、中山祐治
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26430072
[Presentation] Mdm20によるmTORC2シグナル制御機構2015
- Author(s)
  安田邦彦、　森　望
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26430072
[Presentation] Mdm20, a potential regulator for neuronal proteostasis controls mTORC2 activity.2015
- Author(s)
  Kunihiko Yasuda
- Organizer
  The 5th Nagasaki-Pusan Joint Seminar on Aging Research
- Place of Presentation
  長崎大学・ポンペ会館（長崎県）
- Year and Date
  2015-02-06
- Invited
- Data Source
  KAKENHI-PROJECT-26430072
[Presentation] Mdm20によるmTORC2を介した老化作用への効果について2015
- Author(s)
  安田邦彦、　森　望
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-26430072
[Presentation] 初代培養神経細胞におけるHDAC6によるmTORを介したオートファジー誘導について2013
- Author(s)
  安田邦彦、大山恭司、田口祥身、森望
- Organizer
  日本基礎老化学会第36回大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] Mdm20, an auxiliary subunit of the N-terminal acetyltransferase complex NatB, involves in polyQ aggregate clearance2013
- Author(s)
  Yasuda K., Ohyama K. and Mori N
- Organizer
  The 20th IAGG world congress of gerontology and geriatrics
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] N-アセチル化制御関連分子Mdm20はmTORC2活性を介して細胞運動を制御する2013
- Author(s)
  安田邦彦、森望
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] Ageing-dependent TGF beta1 signalling in the neuroprotection against an oxidative stress2013
- Author(s)
  Ohyama K., Yasuda K., Onga K. and Mori N
- Organizer
  The 20th IAGG world congress of gerontology and geriatrics
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] Ageing-dependent adaptive response of primary hippocampal neurons to an oxidative stress by TGF beta12013
- Author(s)
  Ohyama K., Yasuda K., Onga K., and Mori N
- Organizer
  Cold Spring Harbor Conferences Asia
- Place of Presentation
  Suzhou, China
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] Mdm20, an Auxiliary Subunit of the N-terminal Acetyltransferase Complex NatB, Involves in Protein Aggregate Clearance2012
- Author(s)
  安田邦彦
- Organizer
  The 2^<nd> Pusan-Nagasaki Joint Seminar on Aging Research
- Place of Presentation
  Seacloud Hotel, Busan, Korea
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] N-アセチル化制御関連分子Mdm20によるAktのリン酸化制御及びオートファジーを介したpolyQタンパク質排除機構2012
- Author(s)
  安田邦彦、大山恭司、大神和子、垣塚彰、森望
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] Effect of acetyl-modification enzymes on polyQ aggregates formation in primary cultured neurons2011
- Author(s)
  安田邦彦
- Organizer
  The 1^<st> Nagasaki-Pusan Joint Seminar on Aging Research
- Place of Presentation
  福岡ガーデンパレス(福岡県)
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] N-アセチル化酵素によるKAT活性を介したタンパク質品質管理2010
- Author(s)
  安田邦彦、垣塚彰、森望
- Organizer
  第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] N-アセチル化酵素によるKAT活性を介したタンパク質品質管理2010
- Author(s)
  安田邦彦
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] Ageing-Dependent Tgf Beta1 Signalling in the Neuroprotection Against an Oxidative Stress.
- Author(s)
  Ohyama K, Yasuda K, Onga K, Mori N
- Organizer
  第２０回国際老年学会
- Place of Presentation
  ソウル COEX国際会議場(韓国)
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] N-アセチル化制御関連分子Mdm20によるmTORC2活性制御機構
- Author(s)
  安田邦彦、森望
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26430072
[Presentation] 初代培養海馬神経細胞におけるHDAC6によるmTORを介したオートファジー誘導シグナル制御機構について
- Author(s)
  安田邦彦、森望
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26430072
[Presentation] Age-Dependent Adaptive Response of Primary Hippocampal Neurons to an Oxidative Stress by TGF beta1.
- Author(s)
  Ohyama K, Yasuda K, Onga K, Mori N
- Organizer
  Cold Spring Harbor -Asia symposium: Molecular Basis of Aging and Disease
- Place of Presentation
  CSH-Asia, Suzhou（中国・蘇州）
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] MDM20, an Auxiliary Subunit of the N-Terminal Acetyltransferase Coplex NATB, Involves in Polyq Aggregate Clearance.
- Author(s)
  Yasuda K, Ohyama K, Mori N
- Organizer
  第２０回国際老年学会
- Place of Presentation
  ソウル COEX国際会議場(韓国)
- Data Source
  KAKENHI-PROJECT-22300121
[Presentation] The poly-glutamine aggregates clearance by acetyl-modification molecules through the pAkt signaling.
- Author(s)
  Kunihiko Yasuda and Nozomu Mori
- Organizer
  Asian Aging 2015: International Symposium　“Asian Aging Core for Longevity (AACL) 2006-2015, 10 years and Beyond”
- Place of Presentation
  大阪大学中之島センター（大阪府）
- Year and Date
  2015-03-10 – 2015-03-13
- Invited
- Data Source
  KAKENHI-PROJECT-26430072

1. KYOJI Ohyama (00255423)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. HATAYAMA Takumi (10094484)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MORI Nozomu (00130394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
4. MASAHIKO Sibazaki (20445109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SHO Kakizawa (40291059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOKO Hiraishi-yamaguchi (50311345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAGATA Kazuhiro (50127114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAYAMA Yuji (10280918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. SAITO Yohei (90411032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAGISHI Nobuyuki (60298685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 若槻徹 (20121577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 垣塚彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 白石陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YASUDA Kunihiko 安田 邦彦

安田 邦彦 ヤスダ クニヒコ

KUNIHIKO Yasuda 安田 邦彦

Research Projects

Research Products

Co-Researchers

アセチル化修飾によるmTORシグナルの陰陽制御機構と老化制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of neuronal ageing through the mTOR signaling by acetylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Positive and negative regulations of cytoskeletal dynamism and neuronal lifespan

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of stress protein hsp105 during mouse embryo development.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高分子量ストレス蛋白質の構造と機能

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Mdm20 modulates action remodeling through the mTORC2 pathway via its effect on Rictor expression2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mdm20 stimulates PolyQ aggregation via inhibiting autophagy through Akt-Ser473 phosphorylation2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Mdm20 Stimulates PolyQ Aggregation via Inhibiting Autophagy Through Akt-Ser473 Phosphorylation.2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain: Implications for co-operative versus non-co-operative actions of Mdm20 and Nat52012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain : Implications for co-operative versus non-co-operative actions of Mdm20 and Nat52012

Author(s)

Journal Title

Data Source

[Journal Article] Characterization of stress sensitivity and chaperone activity of Hsp105 in mammalian cells2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Maintaining ATP levels via the suppression of PERK-mediated rRNA synthesis at ER stress2010

Author(s)

Journal Title

Data Source

[Presentation] アセチル化修飾による老化シグナルの統括的制御機構の構築2020

Author(s)

Organizer

Data Source

[Presentation] HDAC6によるHSP105との結合を介したHSP70の機能制御2017

Author(s)

Organizer

Data Source

[Presentation] Mdm20によるmTORC2シグナル制御機構2015

Author(s)

Organizer

YASUDA Kunihiko 安田邦彦

安田邦彦ヤスダクニヒコ

KUNIHIKO Yasuda 安田邦彦