MORI Masataka 森正敬

… Alternative Names

森政敬モリマサタカ

森正敞モリマサタカ

森生敬

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Researcher Number	40009650
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004 – 2005: 熊本大学, 大学院医学薬学研究部, 教授 2003 – 2005: Kumamoto University, Grad.Sch.Med.Sci., Professor, 大学院・医学薬学研究部, 教授 1986 – 2002: 熊本大学, 医学部, 教授 1990: 熊本大学, 遺伝研究所, 教授 1986: 熊本大, 医学部, 教授 1985: 千葉大学, 医, 助教授
Review Section/Research Field	Principal Investigator Pathological medical chemistry / General medical chemistry / Pathological medical chemistry / Biological Sciences Except Principal Investigator Pathological medical chemistry / Human genetics / Hematology / Cerebral neurosurgery / Pediatrics
Keywords	Principal Investigator オルニチントランスカルバミラーゼ / 一酸化窒素 / ミトコンドリア / CHOP / 分子シャペロン / アポトーシス / Ornithine transcarbamylase / 尿素サイクル / アルギニノコハク酸リアーゼ / Hsp70 … More / アルギナーゼ / 前駆体タンパク質 / hsp70 / マクロファージ / 一酸化窒素合成酵素 / アルギニン / アルギニノコハク酸合成酵素 / 糖尿病 / cDNAクローニング / 延長ペプチド / サイトソル因子 / Tom20 / オルニチントランスカルバミラ-ゼ / NO合成酵素 / 3-ケトアシルCoAチオラーゼ / ミトコンドリア蛋白質前駆体 / Presequence / PBF / Hsc70 / apoptosis / 小胞体ストレス / ER stress / 分子進化 / トランスジェニックマウス / ミトコンドリアインポート / hsc70 / リポポリサッカライド / GFP / アミロイド形成 / シトルリン / 脾腫 / β細胞 / ストレプトゾトシン / B細胞 / ミトコンドリア形成 / 遺伝子クローニング / 遺伝子の構造 / cDNAの構造 / 内在性ミトコンドリア識別シグナル / 尿素サイクル酵素 / Mitochondrial biogenesis / Precursor protein / Cytosolic factor / オルニチンカルバモイルトランスフェラーゼ / 酵素免疫測定法 / 肝疾患 / 肝機能検査 / Urea cycle / Mitochondria / Zonation / DnaJホモログ / nitric oxide / UPR / 膜透過 / Tom22 / mitochondria / Omi / Bcl-2 / t-Bid / Bim / XBP-1 / LPS / 神経細胞死 / IL-1β / 3-oxoacyl-CoA thiolase / RFLP / アルギニノコハク酸リア-ゼ / δ1-クリスタリン / δ2-クリスタリン / 酵素サイクル / アルギニン合成 / アミノ酸配列の比較 / 遺伝子構造の比較 / 尿素サイクル酵素異常症 / アルギナ-ゼ / エンハンサ- / プロモ-タ- / 窒素排出 / アンモニア排出型動物 / 尿素排出型動物 / 尿酸排出型動物 / プロモーター / アルギナーゼII / アルギナーゼI / 蛍光タンパク質 / 細胞内輸送 / グリオーマ細胞 / 神経細胞 / 免疫システム / MHC / ミトコンドリア識別と膜透過 / プロセシングプロテアーゼ / δクリスタリン / アルギニン合成酵素 / レンズ蛋白質 / 先天性酵素欠損症 / 転写調節 / 組織特異的遺伝子発現 / 蛋白質の膜透過 / PBF(presequence binding factor / プレシ-クエンス / PBF(presequence binding factor) / Presequence binding factor(PBF) / Precursor proteins / Intracellular transport / Cytosolic factors / PBF (presequence binding factor) / プレシークエンス / 肝障害マーカー / ELISA法 / トランスアミナーゼ / カルバミリン酸合成酵素 / Ornithinecarbamoyltransferase / ELISA / Liver disease / Liver funcion test / タンパク質前駆体 / Mitochondrial import / Molecular chaperon / カルバミルリン酸合成酵素 / アルギノコハク酸合成酵素 / 肝小葉内分布 / ゾウネーション / Carbamylphosphate synthetase / Argininosuccinate synthetase / Argininosuccinate lyase / Arginase / アスパラギン酸アミノトランスフェラーゼ / セリン:ビルビン酸アミノランスフェラーゼ / セリン:ピルビン酸アミノトランスフェラーゼ / HSDJ / Protein import / Aspartate aminotransferase / Serine : pyruvate aminotransferase / 中枢神経系 / アストロサイト / リポ多糖 / 免疫染色法 / 遺伝子発現 / 細胞分化 / 肝臓 / 可塑性 / 海馬 / 長期増強 / 長期抑圧 / サブトラクション / nitric oxide synthase / central nervous system / astrocyte / lipopolysaccharide / Immunostaining method / 熱ショックタンパク質 / フォールディング / ミトコンドリア輸送 / タンパク質分泌 / アミロイドーシス / 小胞体 / 葉緑体 / 折り畳み / 品質管理 / アミロイド / タンパク質の細胞内輸送 / カルネキシン / Hsp47 / 小胞輸送 / hsp47 / molecular chaperone / heat shock protein / folding / mitochondria import / secretory protein / amyloidosis / プレ配列 / 前駆体 / Tom34 / インポートレセプター / タンパク質輸送 / precequence / preprotein / translocation / molecular chaperon / arginase / NO / macrophage / NO synthase / arginine / Hsp40 / 熱耐性 / カスパーゼ / 精子形成 / アンドロジェン受容体 / Akiraマウス / Bax / ノックアウトマウス / 分子シヤペロン / diabetes / カスパーゼ11 / 炎症 / グルタミン酸 / 神経栄養因子 / BiP / 骨髄腫 / caspase-11 / inflammation / glutamic acid / neuronal cell death / neurotrophic factor / 遊離ポリソーム / 膜結合ポリソーム / ポリソーム免疫沈降 / 3-ケトアシル-CoAチオラーゼ / Free and membrane-bound polysomes / polysome immunoprecipitation / cDNA clonong / ornithine transcarbamylase / オルニチントランスカルバミナーゼ / オルニテントランスカルバミラーゼ / 3ーケトアシルCoAチオラーゼ / ミトコンドリア蛋白質遺伝子 / ヒドロキシアシルCoAデヒドロゲナーゼ / 蛋白質のミトコンドリア局在化 / mitochondrial protein import / presequence / non-cleavable signal,cDNA sequence / 先天性尿素サイクル病 / 先天性高アンモニア血症 / インスリン受容体異常型糖尿病 / DNA診断 / 尿素サイクル酵素群 / インスリンレセプター / Urea cycle diseases / Hereditary hyperammonemia / Diabetes mellitus / 蛋白質のミトコンドリア移行 / 活性化実験 / 大腸菌での大量発現 / オキソアシルCoAチオラーゼ / 精製前駆体 / 非切断性ミトコンドリア識別シグナル / Mitichondrial protein import / Mitochondrial protein precursor / Ornithine trans-carbamylase / Presequence binding factor / Reactivation experiments / High expression in E. coli … More Except Principal Investigator 遺伝子治療 / 遺伝子発現 / 分子生物学 / 遺伝子解析 / 高脂血症 / トランスジェニックマウス / 転写調節因子 / 単一遺伝病 / 細胞生物学 / ミトコンドリア / 遺伝子単離 / 病因変異 / 生物機能モデル / ヒト疾患モデル / 尿素サイクル / 転写調節 / 核 / 液胞 / プラスチド / 前駆体蛋白質 / 膜透過 / Genetic disease / mitochondrial myopathy / 単一遺伝子病 / 遺伝子診断 / ペルオキシソーム / 海馬 / シトルリン血症 / アルギナーゼ / プロリダーゼ / 色素性乾皮症 / β-サラセミア / 高アンモニア血症 / ストレス蛋白質 / 熱ショック蛋白質 / 分子シャペロン / stress proteins / heat shock proteins / CHOP / ER stress / ischemia / hypoxia / BiP / ステロイドホルモン / グルカゴン / インスリン / サイクリックAMP / 活性型ビタミンD / 糖新生 / 家族性アミロイドニュ-ロパシ- / 高血圧症モデル / ジ-ンタ-ゲッティング法 / ホルモン / 遺伝子 / 調節領域 / 転写因子 / クロマチン / モデル動物 / ジ-ンタ-ゲッティング / 標的遺伝子置換法 / キメラマウス / 高血圧 / ペルオキシソ-ム / positionalcloning / fluoresent in situ hybridization / nonketotic hyperglycinemia / RFLP marker / Prader‐Willi syndrome / colon cancer / ジーンターゲッティング / 胚幹細胞 / 遺伝子欠損モデル / トランスサイレチン / HTLVI / 液泡 / Positional Cloning / Machado-Joseph Disease / Fragile X Syndrome / Amyloid Polyneuropathy / Propionidc acidemia / mitochondrial / Colon Calncer myopathy / Positional cloning / in situ hybridization / nonretotic / P^0cells / aronatase doficienuy / breast cancer / レトロウイルスベクター / アデノウイルスベクター / リポソーム / ジーンターゲッテイング / 遺伝名 / ミトコンドリア病 / 白血病 / 可塑性 / CA1 / 長期増強 / 長期抑圧 / サブトラクション / オルガネラ形成 / プロセシング / リソゾーム / ペルオキシゾーム / 先天性代謝異常症 / 無アルブミン血症 / アルギニノコハク酸リアーゼ / 葉緑体DNAの全構造 / 葉緑体の起源 / オルガネラのイントロン / オルガネラへの輸送シグナル / 多発性骨髄腫 / 高アンモニウム血症 / アミノ酸 / アルギニン / 細胞株 / 形質細胞 / アンモニア / アミノ酸代謝 / 酵素 / グルタミン / オルニチンサイクル / Multiple myeloma / hyperammonemia / amino acid / arginine / cell line / plasma cell / ストレス応答 / モルテングロビュール / HSP47 / HSP70 / 核輸送 / molecular / chaperones / stress response / フォールディング / 品質管理 / シャペロニン / 蛋白質輸送 / プリオン / 細胞内輸送 / 細胞機能制御 / Quality Control / molecular chaperone / protein folding / quality control / chaperonin / transport / prion / 脳梗塞 / 小胞体ストレス / アポトーシス / 線条体 / 脳虚血 / Bip / apoptosis / 先天性高アンモニア血症 / 尿素サイクル異常症 / 有機酸血症 / 全国調査 / 変異酵素 / DNA解析 / 変異遺伝子 / カルニチン代謝 / 尿素サイクル酵素のcDNA / ゲノムDNA / DNA診断 / Congenital hyperammonemia / Urea cycle disorders / Organic acidemia / Retrospective survey / Mutant enzyme / DNA analysis / Mutant gene Less

Basic research for the ER stress-related diseasesPrincipal Investigator
- Principal Investigator
  
  ENDO Motoyoshi, 森正敬
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
糖尿病誘発剤でCHOP破壊マウスに生じた巨大脾腫の解析Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Role of ER-stress on ischemic neuronal cell death
- Principal Investigator
  
  YANO Shigetoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
CHOP遺伝子破壊によりストレプトゾトシン糖尿病モデルで生じた巨大脾腫の謎Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Functional analysis of chaperones in mammalsPrincipal Investigator
- Principal Investigator
  
  TERADA Kazutoyo, 森正敬
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Regulation of nitric oxide (NO) synthesis and NO-induced apoptosisPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
中枢神経系でのアルギニン代謝酵素によるNO産生とアポトーシスの制御Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
中枢神経系でのアルギニン代謝酵素によるNO産生の制御Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
アルギナーゼはNO産生を抑制するか?Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Studies of mitochondrial protein import factors in mammalsPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Regulation of NO synthesis by the urea cycle enzymesPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
タンパク質のミトコンドリア移行:単一細胞レベルでのリアルタイム解析Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Gene cascades in cell differentiation and plasticityPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Regulation of cellular Function by molecular chaperones
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1997 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  KYOTO UNIVERSITY
Roles of molecular chaperones in cell functionPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1997 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
神経活動を制御する階層性遺伝子支配の解析
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
"シトルリン-NOサイクル"は存在するか?Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Molecular Mechanism of Mitoshondrial Protein Import in Higher AnimalsPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
ミトコンドリア蛋白質の移行過程におけるストレス蛋白質の機能Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Structure and function of stress proteins
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University, Chest Disease Research Institute
Development of Enzyme-Linked Immunosorbent Assays for Diagnosis of Liver DiseasesPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
単一遺伝子病の分子・細胞生物学的研究
- Principal Investigator
  
  多田啓也, 勝木元也
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
  Kyushu University
窒素排出の分子進化Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Protein import into mitochondria and its disordersPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
単一遺伝子病の分子・細胞生物学的研究
- Principal Investigator
  
  多田啓也
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
遺伝子治療の基礎研究
- Principal Investigator
  
  松田一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Kumamoto University
核、ミトコンドリア、ペルオキシソーム蛋白質局在化の分子機構
- Principal Investigator
  
  吉田匡
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
病因遺伝子の単離と解析
- Principal Investigator
  
  香川靖雄
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
Protein import into mitochondria and its disordersPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Development of enzyme-linked immunosorbent assay as a liver function testPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
尿素サイクル酵素遺伝子の肝特異的発現を制御する因子
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
核・ミトコンドリア・ペルオキシソ-ム蛋白質局在化の分子機構
- Principal Investigator
  
  斧秀勇
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
単一遺伝子病の分子・細胞生物学的研究
- Principal Investigator
  
  多田啓也
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
単一遺伝子病の分子・細胞生物学的研究
- Principal Investigator
  
  香川靖雄
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
Studies on the hyperammonemia and amino acid disturbances in multiple myeloma
- Principal Investigator
  
  MATSUZAKI Hiromitsu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
尿素サイクル酸素遺伝子の肝特異的発現を制御する因子
- Principal Investigator
  
  滝口正樹
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
ホルモンによる遺伝子発現調節および病態に関する研究
- Principal Investigator
  
  市原明
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
単一遺伝子病の分子・細胞生物学的研究
- Principal Investigator
  
  多田啓也
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Tohoku University
Transport of Proteins into MitochondriaPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
ホルモンによる遺伝子発現調節および病態に関する研究
- Principal Investigator
  
  市原明
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
アルギニノコハク酸リア-ゼからδ-クノスタリンへの分子進化Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
トランスジェニックマウスを用いた尿素サイクル酵素異常症の研究Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
カルバミルリン酸をとりまく代謝酵素系遺伝子の分子進化Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
トランスジェニックマウスを用いた尿素サイクル酵素異常症の研究Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Molecular mechanism of protein import into mitochondriaPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  KUMAMOTO UNIVERSITY
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
先天性代謝異常症の分子遺伝学的研究
- Principal Investigator
  
  佐伯武頼
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kagoshima University
核支配ミトコンドリア蛋白質遺伝子の構造と発現Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kumamoto University
Epidemic and genetic analysis of congenital hyperammonemia
- Principal Investigator
  
  MATSUDA Ichiro
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Kumamoto University
細胞内オルガネラ形成においてのタンパク質のプロセシング
- Principal Investigator
  
  大村恒雄
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
先天性代謝異常症の分子遺伝学的研究
- Principal Investigator
  
  佐伯武頼
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kagoshima University
核支配ミトコンドリア蛋白質遺伝子の構造と発現Principal Investigator
- Principal Investigator
  
  森正敬
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kumamoto University
オルガネラの遺伝的制御
- Principal Investigator
  
  小関治男
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
Structures, Expression and their Desorders of the Genes for Mitochondrial ProteinsPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kumamoto University
Development of DNA diagnosis of urea cycle diseases and diabetes due to insulin receptor abnormalityPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University Medical School
Purification of low-abundance mRNAs by polysome immunoprecipitation and its use for cDNA cloningPrincipal Investigator
- Principal Investigator
  
  MORI Masataka
- Project Period (FY)
  1984 – 1985
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba University

All 2007 2006 2005 2004 Other

All Journal Article Book

[Book] Mammalian HSP40/DnaJ chaperone proteins in cytosol., In Cell Stress Proteins, Protein Reviews, Vol. 7 (ISBN : 978-0-387-39714-6)2007
- Author(s)
  Terada, K. & Mori, M.
- Total Pages
  459
- Publisher
  Springer Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Book] Mammalian HSP40/DnaJ chaperone proteins in cytosol, In Cell Stress Proteins, Protein Reviews Vol. 7 (ISBN : 978-0-387-39714-6)
- Author(s)
  Terada, K., Mori, M.
- Publisher
  Springer Press.(in press)
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] In vitro analysis of Bc1-2 proteins inmitochondria and endoplasmic reticulum : Similarities in anti-apoptotic functions and differences in regulation.2007
- Author(s)
  M. Yano. K. Terada. T. Gotoh. & M. Mori
- Journal Title
  
  Exp. CellRes. 313(17)
  
  Pages: 3767-3778
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] Mammalian HSP40/DnaJ chaperone proteins in cytosol., In Cell Stress Proteins, Ed. S.K. Calderwood, 459pp., Springer Press2007
- Author(s)
  K. Terada & M. Mori
- Journal Title
  
  Protein Reviews Vol. 7
  
  Pages: 255-277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] Mitochondrial import of Omi : The definitive role of the putative transmembrane region and multiple processing sites in the amino-terminal segment.2007
- Author(s)
  T. Kadomatsu, M. Mori, & K. Terada
- Journal Title
  
  Biochem. Biophys. Res. Commun. 361(2)
  
  Pages: 516-521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells.2006
- Author(s)
  M.Nakamura, T.Gotoh, Y.Okuno, H.Tatetsu, T.Sonoki, S.Uneda, M.Mori, H.Mitsuya, H.Hata.
- Journal Title
  
  Leuk. Lymphoma 47
  
  Pages: 531-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats.2006
- Author(s)
  Hasegawa Y, Morioka M, Yano S. et al.
- Journal Title
  
  J Pharmacol Exp ther. 317(2)
  
  Pages: 875-881
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] Nitric oxide and endoplasmic reticulum stress.2006
- Author(s)
  T.Gotoh, M.Mori.
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol. 26
  
  Pages: 1439-1446
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation.2006
- Author(s)
  M.Endo, S.Akira, M.Mori, T.Gotoh*.
- Journal Title
  
  J. Immunol. 176
  
  Pages: 6245-6253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats.2006
- Author(s)
  Hasegawa Y, Morioka M, Yano S. et al.
- Journal Title
  
  J Pharmacol Exp Ther. (In press)
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] CHOP is crucial for the induction of caspase-II and the pathogenesis of LPS-induced inflamation2006
- Author(s)
  Endo M, Mori M, et al.
- Journal Title
  
  J.Immunol. (印刷中)
- Data Source
  KAKENHI-PROJECT-16659087
[Journal Article] CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Regulates Osteoblast Differentiation.2006
- Author(s)
  K.Shirakawa, S.Maeda, T.Gotoh, M.Hayashi, K Shinomiya, S.Ehata, R.Nishimura, M.Mori, K.Onozaki, H.Hayashi, S.Uematsu, S.Akira, E.Ogata, K.Miyazono, T.Imamura.
- Journal Title
  
  Mol. Cell. Biol. 26
  
  Pages: 6105-6116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] Nitric oxide and endoplasmic reticulum stress.2006
- Author(s)
  Gotoh, T, Mori, M.
- Journal Title
  
  Arterioscler. Thromb. Vasc Biol. 26(7)
  
  Pages: 1439-1446
- Data Source
  KAKENHI-PROJECT-14037257
[Journal Article] CHOP is involved in neuronal apoptosis induced by neurotrophic factor deprivation.2006
- Author(s)
  S.Tajiri, S.Yano, M.Moriok, J-I.Kuratsu, M.Mori, T.Gotoh.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 3462-3468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] NMDA-induced retinal injury is mediated by an endoplasmic reticulum stress-related protein, CHOP/ GADD153.2006
- Author(s)
  M.Awai, T.Koga, Y.Inomata, S.Oyadomari, T.Gotoh, M.Mori, H.Tanihara.
- Journal Title
  
  J. Neurochem. 96
  
  Pages: 43-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] The endoplasmic reticulum stress pathway involving CHOP is activated in the lung of the septic shock model mouse.2005
- Author(s)
  M.Endo, S.Oyadomari, M.Suga, M.Mori, T.Gotoh.
- Journal Title
  
  J. Biocem. 138
  
  Pages: 501-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] Functional proteins involved in regulation of intracellular Ca(2+) for drug development : role of calcium/calmodulin-dependent protein kinases in ischemic neuronal death.2005
- Author(s)
  Yano S, Morioka M, Kuratsu J, Fukunaga K.
- Journal Title
  
  J Pharmacol Sci. 2005 97(3)
  
  Pages: 351-354
- NAID
  10025726712
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] Expression of a chondroitin sulfate proteoglycan, versican (PG- M), during development of rat cornea.2005
- Author(s)
  T.Koga, M.Inatani, A.Hirata, Y.Inomata, M.Zako, K.Kimata, A.Oohira, T.Gotoh, M.Mori, H.Tanihara.
- Journal Title
  
  Curr. Eye Res. 30
  
  Pages: 455-463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] Functional proteins involved in regulation of intracellular Ca(2+) for drug development : role of calcium/calmodulin-dependent protein kinases in ischemic neuronal death.2005
- Author(s)
  Yano S, Morioka M, Kuratsu J, Fukunaga K.
- Journal Title
  
  J Pharmacol Sci.2005 97(3)
  
  Pages: 351-354
- NAID
  10025726712
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] 小胞体ストレスと糖尿病2004
- Author(s)
  森正敬
- Journal Title
  
  (蛋白質核酸酵素増刊)細胞における蛋白質の一生
  
  Pages: 1131-1132
- Data Source
  KAKENHI-PROJECT-16659087
[Journal Article] Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus2004
- Author(s)
  Hashiguchi A, Yano S, Morioka M et al.
- Journal Title
  
  J Cereb Blood flow Metab. 24(3)
  
  Pages: 271-279
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus2004
- Author(s)
  Hashiguchi A, Yano S, Morioka M et al.
- Journal Title
  
  J Cereb Blood Flow Metab. 24(3)
  
  Pages: 271-279
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] Roles of CHOP/GADD153 in endoplasmic reticulum stress2004
- Author(s)
  Oyadomari, S., Mori, M.
- Journal Title
  
  Cell Death Differ. 11
  
  Pages: 381-389
- Data Source
  KAKENHI-PROJECT-16659087
[Journal Article] Contribution of angiotensin-converting enzyme and angiotensin II to ischemic stroke : their role in the formation of stable and unstable carotid atherosclerotic plaques.2004
- Author(s)
  Morioka M, Hamada J et al.
- Journal Title
  
  Surg Neurol 62(4)
  
  Pages: 301-303
- Data Source
  KAKENHI-PROJECT-16591448

1. TAKIGUCHI Masaki (40179578)

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2. GOTOH Tomomi (20264286)

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3. TERADA Kazutoyo (00253724)

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MORI Masataka 森 正敬

森 政敬 モリ マサタカ

森 正敞 モリ マサタカ

森 生敬

Research Projects

Research Products

Co-Researchers

Basic research for the ER stress-related diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糖尿病誘発剤でCHOP破壊マウスに生じた巨大脾腫の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of ER-stress on ischemic neuronal cell death

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CHOP遺伝子破壊によりストレプトゾトシン糖尿病モデルで生じた巨大脾腫の謎Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of chaperones in mammalsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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Regulation of nitric oxide (NO) synthesis and NO-induced apoptosisPrincipal Investigator

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中枢神経系でのアルギニン代謝酵素によるNO産生とアポトーシスの制御Principal Investigator

Principal Investigator

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中枢神経系でのアルギニン代謝酵素によるNO産生の制御Principal Investigator

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アルギナーゼはNO産生を抑制するか?Principal Investigator

Principal Investigator

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Studies of mitochondrial protein import factors in mammalsPrincipal Investigator

Principal Investigator

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Regulation of NO synthesis by the urea cycle enzymesPrincipal Investigator

Principal Investigator

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タンパク質のミトコンドリア移行:単一細胞レベルでのリアルタイム解析Principal Investigator

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Gene cascades in cell differentiation and plasticityPrincipal Investigator

MORI Masataka 森正敬

森政敬モリマサタカ

森正敞モリマサタカ

森生敬