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KOCHI Masato
河内 正人
Connect your ORCID iD
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Researcher Number
70178218
Other IDs
External Links
Affiliation (based on the past Project Information)
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2004: 熊本大, 助教授
2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 助教授
1997 – 2002: 熊本大学, 医学部, 助教授
1996 – 1997: Kumamoto University School of Medicine Lecturer, 医学部, 講師
1992 – 1993: 熊本大学, 医学部, 講師
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1987 – 1991: Kumamoto Univ.Med.Sch.Hospital Neurosurg.Instructor, 医学部附属病院, 助手
1990: Kumamoto Univ. Hospital, Instructor Neurosurgery, 医学部・附属病院, 助手
1988: KUMAMOTO UNIVERSITY MEDICAL SCHOOL, NEUROSURGERY,ASSISTANT LECTURER, 医学部付属病院, 助手
1986: 熊本大学, 医学部附付病院, 助手
Less
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery
/
Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
/
Cerebral neurosurgery
/
Biological Sciences
Keywords
Principal Investigator
悪性脳腫瘍 / malignant glioma / MCP-1 / 髄腔内播種 / グリオーマ / IL-12 / 悪性グリオーマ / electro-gene therapy / ニトロソウレア / MALIGNANT GLIOMAS
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/ 電気穿孔法 / 脳腫瘍 / 髄腔内潅流化学療法 / SUBARACHNOID DISSEMINATION / 膜型チロシンキナーゼ / monkey / 遺伝子治療 / アポトーシス / brain tumor / subarachnoid dissemination / radio-chemosensitivity / E1Aプラスミド / EGFレセプター / INTRATHECAL CHEMOTHERAPY / 標的治療 / 髄腔内化学療法 / apoptosis / clinical application / suicide gene / NITROSOUREAS / リボソーム / リポソーム / 髄液腔内潅流療法 / 自殺遺伝子 / BCNU / LIPOSOME / 臨床応用 / 放射線化学療法感受性 / 脳腫瘍モデル / ACNU / 安全性 / 神経膠腫(グリオーマ)
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Except Principal Investigator
グリオーマ / MCP-1 / Glioma / 脳腫瘍 / マクロファージ / ケモカイン / サイトカイン / malignant glioma / glioma / 遺伝子治療 / gene therapy / 電気遺伝子療法 / monocyte / promoter / 生体内電気穿孔法 / Macrophage / 増殖因子 / IL-12 / cloning / CCR2 / 自殺遺伝子 / 悪性脳腫瘍 / 免疫 / luciferase / Growth Factor / combination electro-gene therapy / 単球 / p53 / プロモーター / hypoxia / therapy / p16 / PDGF / ACNU / BiP / cytosine deaminase / C / HS-tk / methylation / growth factor / MCP-1 receptor / 5-FC / classification / 浸潤 / chemotherapy / ischemia / gene regulation / 5-FU / EGFR / Angiogenesis / ADH / 抗癌剤 / gene analysis / ER stress / dissemination / Oct-1 / Chemotherapy / NF2 / chemokine / CHOP / prognosis / gene / HSV1yCD / drug delivery / EBP / DIAGNOSIS / 電気穿孔法 / 海馬 / anti-cancer drug / microsphere / Cytokine / シアル酸 / 癌化学療法 / クローニング / BRAIN TUMOR / Oncolytic virus / TAT-p16 / カルシニュリン / apoptosis / malignant brain tumor / suicide gene / ganglioglioma / 線条体 / GST融合蛋白 / Drug-resistant / 膜表面物質 / 小胞体ストレス / PTEN / CT26 tumor / plasmid DNA / Macro phage / SIALIC ACID / FIBRONECTIN / Invasin / 髄腔内播種 / LOH 10 / 生存日数 / 転写因子 / invasin / ヘルペスウィルスベクター / インターフェロン / ADHESIVE FACTOR / oncolytic virus / neurocytoma / 10番染色体 / Hsv-tk / medulloblastoma / 臨床応用 / スフェロイド培養 / MCP-1遺伝子 / 視床下部腫瘍 / 脳虚血 / LOH10 / 髄液腔 / 遺伝子療法 / Immunity / Trapidil / TAT-GFP / 受容体 / アポトーシス / CSF DISSEMINATION / MCP-1レセプター / electro-genetherapy (EGT) / 核磁気共鳴 / 髄液腔内播種 / 接着分子 / 脳梗塞 / C6グリオーマ細胞 / Fluocytometry / Calcineurin / カルモデュリン / glioblastoma / fractalkine / 遊走因子 / 脳腫瘍転移 / Dissemination / TAT-lacZ / Bip / hMCP1 / lac Z gene / フラクタルカイン / lacZ遺伝子 / electro-gene therapy / LOH / グリコーゲン合成酵素 / 癌細胞凝集因子 / DT-A / in vivo electroporation / 制癌剤 / brain tumor / 薬剤耐性 / 機能的解析 / TATペプチド融合蛋白 / EST / CSF PERFUSION / chemokine gene / ライブラリースクリーニング / 転移 / リンパ球 / プラスミドDNA / GST-fusion protein / human MCP-1遺伝子 / アポ蛋白E / マイクロスフィアー / Herpes virus vector
Less
Research Projects
(
26
results)
Co-Researchers
(
27
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Role of ER-stress on ischemic neuronal cell death
Principal Investigator
YANO Shigetoshi
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
アデノウィルスの遺伝子産物E1A発現プラスミドを用いた悪性脳腫瘍の治療法の開発
Principal Investigator
Principal Investigator
河内 正人
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
Development of the gene therapy for the malignant brain tumor using the oncolytic herpes virus vector
Principal Investigator
NAKAMURA Hideo
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
生体内電気穿孔法を用いた電気遺伝子療法の臨床応用へ向けた安全性に関する研究
Principal Investigator
生塩 之敬
Project Period (FY)
2001
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Kumamoto University
Research for clinical application of electro-gene therapy against malignant brain tumor
Principal Investigator
Principal Investigator
KOCHI Masato
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
固形癌に対する自殺遺伝子とサイトカイン遺伝子群を併用した複合電気遺伝子療法の開発
Principal Investigator
生塩 之敬
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Kumamoto University
悪性脳腫瘍の自殺遺伝子・複数サイトカイン遺伝子を用いた複合電気遺伝子療法の開発
Principal Investigator
西 徹
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
シッピシグ・タグ付加レコンビナント蛋白質の髄液内投与と悪性脳腫瘍治療への応用
Principal Investigator
生塩 之敬
Project Period (FY)
2000
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
Research for pathophysiology of subarachnoid dissemination of malignant brain tumors
Principal Investigator
Principal Investigator
KOCHI Masato
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
CLASSIFICATION OF MALIGNANT GLIOMAS BY MOLECULAR GENETIC ANALYSIS TO DEVELOP RATIONAL THERAPY
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Role of NF2 tumor suppressor gene promoter in the tumorigenesis
Principal Investigator
TAKESHIMA Hideo
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kagoshima University
Kumamoto University
脳腫瘍における模型ケモカインのクローニングと解析
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
Development of a method for combination electro-gene therapy using suicide gene and chemokine gene(s)
Principal Investigator
NISHI Toru
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Developement of a method for cancer treatment using invsin-conjugated microsphere
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Development plan of the new treatment for malignant glioma using Monocyte Chemoattrctant Protein-1
Principal Investigator
KURATSU Jun-ichi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kagoshima University
Kumamoto University
Development of the Gene-missile therapy against human malignant gliomas using monocyte as a carrier.
Principal Investigator
TAKESHIMA Hideo
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
悪性グリオーマにおけるマクロファージ浸潤とその意義および臨床応用に向けて
Principal Investigator
倉津 純一
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
New approach for the treatment of glioblastomas.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
DEVELOPMENT OF GENE TRANSFER METHOD FOR SOLID TUMORS USING IN VIVO ELECTROPORATION.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
グリオーマにおける単球遊走因子の遺伝子発現とその調節機構
Principal Investigator
倉津 純一
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
INTRATHECAL CHEMOTHERAPY AGAINST SUBARACHNOID DISSEMINATION OF MALIGNANT BRAIN TUMORS
Principal Investigator
Principal Investigator
HAMADA Junichiro
, 河内 正人
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
グリオーマにおける単球遊走因子の遺伝子発現とその調節機構
Principal Investigator
KURATSU Jun-ichi
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
A Study for New Approaches in the Treatment of Malignant Gliomas.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Molecular Cell Biology of Drug-resistant Glioma and Treatment.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
BIOLOGICAL SPECIALITY OF THE TUMOR CELL MEMBRANE IN RELATION TO THE MECHANISM OF BRAIN TUMOR INFILTRATION,DISSEMINATION AND METASTASIS- BASIC AND CLINICAL EXPERIMENT-
Principal Investigator
MATSUKADO Yasuhiko
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Role of ADH to Central nervous system Function -With special Reference ot Ca ion-
Principal Investigator
UEMURA Shozaburo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
# of Projects (Dsc)
# of Projects (Asc)
1.
USHIO Yukitaka
(20028583)
# of Collaborated Projects:
17 results
# of Collaborated Products:
0 results
2.
NISHI Toru
(00264309)
# of Collaborated Projects:
15 results
# of Collaborated Products:
0 results
3.
KURATSU Jun-ichi
(20145296)
# of Collaborated Projects:
13 results
# of Collaborated Products:
0 results
4.
TAKESHIMA Hideo
(70244134)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
5.
MIHARA Masaki
(00192352)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
UEMURA Shozaburo
(00128258)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
SETO Hiroshi
(60209848)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
YANO Shigetoshi
(60332871)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
MORIOKA Motohiro
(20295140)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
TAKADA Akira
(10187966)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
NAGAHIRO Shinji
(60145315)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
SAYA Hideyuki
(80264282)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
GOTO Satoshi
(50240916)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
HAMADA Junichiro
(40253752)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
MATSUKADO Yasuhiko
(30037337)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
YOSHIOKA Susumu
(00182725)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
児玉 万典
(60040581)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
NAKANO Masahiro
(40002125)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
HIRANO Hirofumi
(00264416)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
YOKOYAMA Shunichi
(90191519)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
SAITO Yoshiki
(50304994)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
NAKAMURA Hideo
(30359963)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
KAI Yutaka
(30322308)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
MORI Masataka
(40009650)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
和田 伸一
(30094056)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
SUGIMOTO Yoshikazu
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
SAKATA Tsuneaki
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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