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KOCHI Masato
河内 正人
Connect your ORCID iD
*help
Researcher Number
70178218
Other IDs
External Links
Affiliation (based on the past Project Information)
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2004: 熊本大, 助教授
2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 助教授
1997 – 2002: 熊本大学, 医学部, 助教授
1996 – 1997: Kumamoto University School of Medicine Lecturer, 医学部, 講師
1992 – 1993: 熊本大学, 医学部, 講師
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1987 – 1991: Kumamoto Univ.Med.Sch.Hospital Neurosurg.Instructor, 医学部附属病院, 助手
1990: Kumamoto Univ. Hospital, Instructor Neurosurgery, 医学部・附属病院, 助手
1988: KUMAMOTO UNIVERSITY MEDICAL SCHOOL, NEUROSURGERY,ASSISTANT LECTURER, 医学部付属病院, 助手
1986: 熊本大学, 医学部附付病院, 助手
Less
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery
/
Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
/
Biological Sciences
/
Cerebral neurosurgery
Keywords
Principal Investigator
悪性脳腫瘍 / 悪性グリオーマ / 髄腔内播種 / グリオーマ / malignant glioma / IL-12 / MCP-1 / 膜型チロシンキナーゼ / EGFレセプター / 標的治療
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/ E1Aプラスミド / 髄腔内化学療法 / ニトロソウレア / リボソーム / BCNU / リポソーム / 髄液腔内潅流療法 / 神経膠腫(グリオーマ) / 髄腔内潅流化学療法 / ACNU / MALIGNANT GLIOMAS / SUBARACHNOID DISSEMINATION / INTRATHECAL CHEMOTHERAPY / NITROSOUREAS / LIPOSOME / アポトーシス / 放射線化学療法感受性 / apoptosis / radio-chemosensitivity / subarachnoid dissemination / 電気穿孔法 / 遺伝子治療 / 脳腫瘍 / 自殺遺伝子 / 臨床応用 / 脳腫瘍モデル / 安全性 / electro-gene therapy / brain tumor / suicide gene / clinical application / monkey
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Except Principal Investigator
グリオーマ / MCP-1 / Glioma / 脳腫瘍 / マクロファージ / サイトカイン / ケモカイン / 遺伝子治療 / 電気遺伝子療法 / glioma / malignant glioma / monocyte / gene therapy / promoter / Macrophage / cloning / IL-12 / 自殺遺伝子 / 生体内電気穿孔法 / 悪性脳腫瘍 / 増殖因子 / CCR2 / 免疫 / chemokine / 浸潤 / HS-tk / combination electro-gene therapy / growth factor / therapy / PDGF / dissemination / Growth Factor / Chemotherapy / MCP-1 receptor / drug delivery / chemotherapy / 単球 / プロモーター / 抗癌剤 / Angiogenesis / Oct-1 / C / EBP / gene regulation / gene analysis / p53 / p16 / EGFR / prognosis / classification / NF2 / gene / luciferase / methylation / HSV1yCD / 5-FC / 5-FU / cytosine deaminase / CHOP / ER stress / ischemia / hypoxia / BiP / ACNU / ADH / Immunity / Cytokine / 遊走因子 / fractalkine / neurocytoma / ganglioglioma / medulloblastoma / フラクタルカイン / クローニング / 接着分子 / EST / ライブラリースクリーニング / TATペプチド融合蛋白 / TAT-lacZ / TAT-p16 / 髄腔内播種 / C6グリオーマ細胞 / TAT-GFP / 電気穿孔法 / Hsv-tk / DT-A / 臨床応用 / Trapidil / Dissemination / Fluocytometry / プラスミドDNA / lacZ遺伝子 / human MCP-1遺伝子 / MCP-1遺伝子 / hMCP1 / electro-genetherapy (EGT) / in vivo electroporation / brain tumor / lac Z gene / plasmid DNA / リンパ球 / 転写因子 / MCP-1レセプター / 遺伝子療法 / invasin / マイクロスフィアー / GST融合蛋白 / Invasin / microsphere / anti-cancer drug / GST-fusion protein / Macro phage / 受容体 / electro-gene therapy / suicide gene / chemokine gene / CT26 tumor / LOH10 / glioblastoma / 10番染色体 / LOH / PTEN / 生存日数 / 機能的解析 / LOH 10 / ヘルペスウィルスベクター / oncolytic virus / Herpes virus vector / malignant brain tumor / Oncolytic virus / 脳梗塞 / 小胞体ストレス / アポトーシス / 海馬 / 線条体 / 脳虚血 / Bip / apoptosis / 脳腫瘍転移 / 髄液腔 / シアル酸 / 髄液腔内播種 / 転移 / アポ蛋白E / 癌細胞凝集因子 / スフェロイド培養 / 膜表面物質 / 核磁気共鳴 / BRAIN TUMOR / CSF DISSEMINATION / DIAGNOSIS / CSF PERFUSION / SIALIC ACID / ADHESIVE FACTOR / FIBRONECTIN / 視床下部腫瘍 / カルシニュリン / グリコーゲン合成酵素 / カルモデュリン / Calcineurin / 癌化学療法 / 薬剤耐性 / 制癌剤 / インターフェロン / Drug-resistant
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Research Projects
(
26
results)
Co-Researchers
(
27
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Role of ER-stress on ischemic neuronal cell death
Principal Investigator
YANO Shigetoshi
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
アデノウィルスの遺伝子産物E1A発現プラスミドを用いた悪性脳腫瘍の治療法の開発
Principal Investigator
Principal Investigator
河内 正人
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
Development of the gene therapy for the malignant brain tumor using the oncolytic herpes virus vector
Principal Investigator
NAKAMURA Hideo
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
生体内電気穿孔法を用いた電気遺伝子療法の臨床応用へ向けた安全性に関する研究
Principal Investigator
生塩 之敬
Project Period (FY)
2001
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Kumamoto University
Research for clinical application of electro-gene therapy against malignant brain tumor
Principal Investigator
Principal Investigator
KOCHI Masato
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
固形癌に対する自殺遺伝子とサイトカイン遺伝子群を併用した複合電気遺伝子療法の開発
Principal Investigator
生塩 之敬
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Kumamoto University
悪性脳腫瘍の自殺遺伝子・複数サイトカイン遺伝子を用いた複合電気遺伝子療法の開発
Principal Investigator
西 徹
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
シッピシグ・タグ付加レコンビナント蛋白質の髄液内投与と悪性脳腫瘍治療への応用
Principal Investigator
生塩 之敬
Project Period (FY)
2000
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
Research for pathophysiology of subarachnoid dissemination of malignant brain tumors
Principal Investigator
Principal Investigator
KOCHI Masato
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
CLASSIFICATION OF MALIGNANT GLIOMAS BY MOLECULAR GENETIC ANALYSIS TO DEVELOP RATIONAL THERAPY
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Role of NF2 tumor suppressor gene promoter in the tumorigenesis
Principal Investigator
TAKESHIMA Hideo
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kagoshima University
Kumamoto University
脳腫瘍における模型ケモカインのクローニングと解析
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
Development of a method for combination electro-gene therapy using suicide gene and chemokine gene(s)
Principal Investigator
NISHI Toru
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Developement of a method for cancer treatment using invsin-conjugated microsphere
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Development plan of the new treatment for malignant glioma using Monocyte Chemoattrctant Protein-1
Principal Investigator
KURATSU Jun-ichi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kagoshima University
Kumamoto University
Development of the Gene-missile therapy against human malignant gliomas using monocyte as a carrier.
Principal Investigator
TAKESHIMA Hideo
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
悪性グリオーマにおけるマクロファージ浸潤とその意義および臨床応用に向けて
Principal Investigator
倉津 純一
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
New approach for the treatment of glioblastomas.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
DEVELOPMENT OF GENE TRANSFER METHOD FOR SOLID TUMORS USING IN VIVO ELECTROPORATION.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
グリオーマにおける単球遊走因子の遺伝子発現とその調節機構
Principal Investigator
倉津 純一
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
INTRATHECAL CHEMOTHERAPY AGAINST SUBARACHNOID DISSEMINATION OF MALIGNANT BRAIN TUMORS
Principal Investigator
Principal Investigator
HAMADA Junichiro
, 河内 正人
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
グリオーマにおける単球遊走因子の遺伝子発現とその調節機構
Principal Investigator
KURATSU Jun-ichi
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
A Study for New Approaches in the Treatment of Malignant Gliomas.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Molecular Cell Biology of Drug-resistant Glioma and Treatment.
Principal Investigator
USHIO Yukitaka
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
BIOLOGICAL SPECIALITY OF THE TUMOR CELL MEMBRANE IN RELATION TO THE MECHANISM OF BRAIN TUMOR INFILTRATION,DISSEMINATION AND METASTASIS- BASIC AND CLINICAL EXPERIMENT-
Principal Investigator
MATSUKADO Yasuhiko
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
KUMAMOTO UNIVERSITY
Role of ADH to Central nervous system Function -With special Reference ot Ca ion-
Principal Investigator
UEMURA Shozaburo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Kumamoto University
# of Projects (Dsc)
# of Projects (Asc)
1.
USHIO Yukitaka
(20028583)
# of Collaborated Projects:
17 results
# of Collaborated Products:
0 results
2.
NISHI Toru
(00264309)
# of Collaborated Projects:
15 results
# of Collaborated Products:
0 results
3.
KURATSU Jun-ichi
(20145296)
# of Collaborated Projects:
13 results
# of Collaborated Products:
0 results
4.
TAKESHIMA Hideo
(70244134)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
5.
MIHARA Masaki
(00192352)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
UEMURA Shozaburo
(00128258)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
SETO Hiroshi
(60209848)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
YANO Shigetoshi
(60332871)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
MORIOKA Motohiro
(20295140)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
TAKADA Akira
(10187966)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
NAGAHIRO Shinji
(60145315)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
SAYA Hideyuki
(80264282)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
GOTO Satoshi
(50240916)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
HAMADA Junichiro
(40253752)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
MATSUKADO Yasuhiko
(30037337)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
YOSHIOKA Susumu
(00182725)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
児玉 万典
(60040581)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
NAKANO Masahiro
(40002125)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
HIRANO Hirofumi
(00264416)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
YOKOYAMA Shunichi
(90191519)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
SAITO Yoshiki
(50304994)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
NAKAMURA Hideo
(30359963)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
KAI Yutaka
(30322308)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
MORI Masataka
(40009650)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
和田 伸一
(30094056)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
SUGIMOTO Yoshikazu
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
SAKATA Tsuneaki
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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