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Takeshima Hideo  竹島 秀雄

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… Alternative Names

TAKESHIMA Hideo  竹島 秀雄

竹島 秀雄  タケシマ ヒデオ

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Researcher Number 70244134
Other IDs
External Links
Affiliation (Current) 2022: 宮崎大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2015 – 2022: 宮崎大学, 医学部, 教授
2013: 宮崎大学, 医学部, 教授
2006 – 2010: 宮崎大学, 医学部, 教授
2005: 熊本大学, 医学部附属病院, 講師
2004: Kagoshima University Hospital, Faculty of Medicine and Dentistry, Lecturer, 大学院・医歯学総合研究科, 講師 … More
2003 – 2004: Kagoshirna University, University Hospital, Facultyof Medicine and Dentistry, Assistant Professor, 医学部・歯学部附属病院, 講師
2003: Kagoshima University, University Hospital, Faculty of Medicine and Dentistry, Assistant Professor, 歯学部附属病院, 講師
2002: Kagoshima University, Medical Hospital, Assistant Professor, 医学部附属病院, 講師
2000 – 2001: University Hospital Faculty of Medicine, Kagoshima university, Assistant Professor, 医学部・附属病院, 講師
1995 – 1999: KUMAMOTO UNIV., of SCH.MED INSTRACTORE, 医学部, 助手
1998: 熊本大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery / Cerebral neurosurgery / Neurosurgery / Basic Section 56010:Neurosurgery-related
Except Principal Investigator
Cerebral neurosurgery / Neurosurgery / Basic Section 56010:Neurosurgery-related
Keywords
Principal Investigator
グリオーマ / MCP-1 / promoter / マクロファージ / プロモーター / 乏突起膠腫 / monocyte / CCR2 / Oct-1 / C … More / EBP / gene regulation / glioma / ケモカイン / NF2 / gene / cloning / luciferase / methylation / LARC / TARC / Immunotherapy / s-kit / SCF / ABCA2 / MCP-1受容体 / 発現調節機構 / 癌幹細胞 / 分子マーカー / 分化誘導 / 乏突紀膠腫 / 分子マーカニ / 単球 / 受容体 / LARK / Chemokine / Glioma / Germ cell tumor / Germinoma / Tumor marker / c-kit / Stem cell factor / germ cell tumor / germinoma / tumor marker / c-kir / 悪性グリオーマ / 腫瘍免疫 / TGF-β / TGF-b / malignant glioma / tumor immunology / TGF-[○!R] / oligodendroglioma / microvascular / proliferation / KIAA-BRAF / fusion gene / pilocytic astrocytoma / microdissection / mesenchymal / transition / fusion / astrocytoma laser / KIAA-BRAF fusion gene / laser microdissection / LA-PCR / mesenchymal traisition / Pilocytic astrocytoma / 毛様細胞性星細胞腫 / mesenchymal transition / 膠肉腫 / 間葉型形質転換 / DNAメチル化アレイ解析 / Classifier / CRC culture / 上皮間葉転換 … More
Except Principal Investigator
MCP-1 / グリオーマ / ケモカイン / マクロファージ / NF1 / malignant glioma / Macrophage / macrophage / apoptosis / サイトカイン / 浸潤 / EGFR / glioma / integrin / 脳腫瘍 / gene therapy / Glioma / p53 / glioblastoma / 神経膠芽腫 / 免疫 / chemokine / PDGF / NF2 / 増殖因子 / 電気遺伝子療法 / monocyte / MCP-1 receptor / drug delivery / chemotherapy / 抗癌剤 / Angiogenesis / gene analysis / p16 / prognosis / classification / PTEN / 血管新生 / トロンビン / angiogenesis / temporal lobe epilepsy / limbic seizures / kainic acid / spontaneous seizures / epilepsy surgery / hippocampal transection / rat / intractable epilepsy / docosahexaenoic acid / 5-FU / 代謝回路再編成 / エピジェネティクス / 遊走因子 / fractalkine / cloning / neurocytoma / ganglioglioma / medulloblastoma / フラクタルカイン / クローニング / 接着分子 / EST / ライブラリースクリーニング / EVI1 / neural precurser cell / glioma initiating cell / NOTCH / GIC / laminin / Notch / VEGF / トラピジ-ル / スラミン / グリオーマ細胞 / Neurofibromatosis / 遺伝子 / 細胞内情報伝達 / GLIOMA / TRAPIGIL / SURAMIN / 生体内電気穿孔法 / プラスミドDNA / lacZ遺伝子 / human MCP-1遺伝子 / MCP-1遺伝子 / hMCP1 / electro-genetherapy (EGT) / in vivo electroporation / brain tumor / lac Z gene / plasmid DNA / CCR2 / 単球 / リンパ球 / 転写因子 / プロモーター / MCP-1レセプター / 遺伝子療法 / invasin / マイクロスフィアー / GST融合蛋白 / Invasin / microsphere / anti-cancer drug / GST-fusion protein / Macro phage / 自殺遺伝子 / 悪性脳腫瘍 / electro-gene therapy / suicide gene / chemokine gene / CT26 tumor / LOH10 / 10番染色体 / LOH / 生存日数 / 機能的解析 / LOH 10 / スタチン / neovascula rization / Invasion / statin / インテグリン / ドコサヘキサエンサン / アポトーシス / c-kit / 胚細胞腫 / NF-1 / EGF-R / NO / inteacrable epilepsy / intracrable epilepsy / 分子標的療法 / 代謝経路再編成 / 上皮間葉転換 / 多剤併用療法 / 遺伝子解析 / 多剤併用化学療法 / 脳腫瘍学 / 腫瘍内不均一性 / 表現型可塑性 / メチオニン / 代謝 / 概日リズム / 幹細胞 Less
  • Research Projects

    (26 results)
  • Research Products

    (75 results)
  • Co-Researchers

    (26 People)
  •  代謝経路再編成が概日リズム経路を介し、幹細胞性維持、細胞死回避に及ぼす影響の解明

    • Principal Investigator
      横上 聖貴
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      University of Miyazaki
  •  神経膠芽腫において代謝経路再編成が細胞増殖や治療抵抗性に与える機序の解明

    • Principal Investigator
      渡邉 孝
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      University of Miyazaki
  •  Elucidation of the molecular mechanisms underlying mesenchymal transition of glioma cells using methylation array analysisPrincipal Investigator

    • Principal Investigator
      Takeshima Hideo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      University of Miyazaki
  •  Origin of the microvascular proliferation in pilocytic astrocytomaPrincipal Investigator

    • Principal Investigator
      takeshima hideo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      University of Miyazaki
  •  Targeted Molecular Therapy Against the Multiple Signaling Pathways in Glioblastoma

    • Principal Investigator
      Watanabe Takashi
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      University of Miyazaki
      University of the Ryukyus
  •  Function of Ecotropic Viral Integration Site 1 (EVI1) gene in neural precurser cells and human glioma cells

    • Principal Investigator
      Kiyotaka Yokogami
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      University of Miyazaki
  •  Identification of the novel molecular marker for oligodendroglial tumor using induced differentiation system against glioma stem cell.Principal Investigator

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      University of Miyazaki
  •  Mechanisms underlying inhibition of tumor-immunology in malignant glioma and development of immune-activation therapy using suicide-chimeric moleculePrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      University of Miyazaki
      Kumamoto University
  •  Development of the clinical diagnosis and treatment of CNS germinoma using KIT as a targetPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
  •  The pathophysiology of malignant glioma and of treatment strategies

    • Principal Investigator
      KURATSU Jun-ichi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
      Kagoshima University
  •  Experimental studies on the clinical appliance of hippocampal transection to I intractable mesiotemporal lobe epilepsy

    • Principal Investigator
      IMAMURA Shinichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
  •  Immuno-chemo-therapy for malignant brain tumors with immunocompetent cells from peripheral blood cells

    • Principal Investigator
      HIRANO Hirofumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
  •  Development of chemokine-cocktail therapy against hyman malignant gliomas using lymphocyte-specific chemokinesPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
  •  CLASSIFICATION OF MALIGNANT GLIOMAS BY MOLECULAR GENETIC ANALYSIS TO DEVELOP RATIONAL THERAPY

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  The study of the pathophysiology of malignant glioma and development of treatment strategies

    • Principal Investigator
      KURATSU Jun-ichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
  •  Role of NF2 tumor suppressor gene promoter in the tumorigenesisPrincipal Investigator

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
      Kumamoto University
  •  脳腫瘍における模型ケモカインのクローニングと解析

    • Principal Investigator
      生塩 之敬
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  Development of a method for combination electro-gene therapy using suicide gene and chemokine gene(s)

    • Principal Investigator
      NISHI Toru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Developement of a method for cancer treatment using invsin-conjugated microsphere

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Development plan of the new treatment for malignant glioma using Monocyte Chemoattrctant Protein-1

    • Principal Investigator
      KURATSU Jun-ichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
      Kumamoto University
  •  Development of the Gene-missile therapy against human malignant gliomas using monocyte as a carrier.Principal Investigator

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  悪性グリオーマにおけるマクロファージ浸潤とその意義および臨床応用に向けて

    • Principal Investigator
      KURATSU Junichi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  単球遊走因子受容体の発現調節機構の解明と脳腫瘍治療への応用Principal Investigator

    • Principal Investigator
      竹島 秀雄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  New approach for the treatment of glioblastomas.

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  DEVELOPMENT OF GENE TRANSFER METHOD FOR SOLID TUMORS USING IN VIVO ELECTROPORATION.

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Establishment of the New Approach to the Treatment of Malignant Glioma

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY

All 2021 2020 2019 2018 2016 2013 2010 2009 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] 入門腫瘍内科学日本臨床腫瘍学会監修2009

    • Author(s)
      竹島秀雄
    • Total Pages
      301
    • Publisher
      篠原出版新社
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Book] 中枢神経系腫瘍in入門腫瘍内科学(日本臨床腫瘍学会監修)2009

    • Author(s)
      竹島秀雄
    • Publisher
      篠原出版新社、東京
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Journal Article] Characteristics of Preoperative Visual Disturbance and Visual Outcome After Endoscopic Endonasal Transsphenoidal Surgery for Nonfunctioning Pituitary Adenoma in Elderly Patients2019

    • Author(s)
      Takashi Watanabe, Hisao Uehara, Go Takeishi, Hideki Chuman, Minako Azuma, Kiyotaka Yokogami, Toshinori Hirai, Hideo Takeshima
    • Journal Title

      World Neurosurgery

      Volume: Mar 5

    • DOI

      10.1016/j.wneu.2019.02.132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Journal Article] Evaluation of pituitary structures and lesions with turbo spin-echo diffusion-weighted imaging2019

    • Author(s)
      Khant Zaw Aung、Azuma Minako、Kadota Yoshihito、Hattori Youhei、Takeshima Hideo、Yokogami Kiyotaka、Watanabe Takashi、Enzaki Masahiro、Nakaura Takeshi、Hirai Toshinori
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 405 Pages: 116390-116390

    • DOI

      10.1016/j.jns.2019.07.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Journal Article] Detection of the KIAA1549-BRAF fusion gene in cells forming microvascular proliferations in pilocytic astrocytoma2019

    • Author(s)
      Yamashita Shinji、Takeshima Hideo、Matsumoto Fumitaka、Yamasaki Kouji、Fukushima Tsuyoshi、Sakoda Hideyuki、Nakazato Masamitsu、Saito Kiyotaka、Mizuguchi Asako、Watanabe Takashi、Ohta Hajime、Yokogami Kiyotaka
    • Journal Title

      PLOS ONE

      Volume: 14 Pages: 1-13

    • DOI

      10.1371/journal.pone.0220146

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03773, KAKENHI-PROJECT-16K10764
  • [Journal Article] Usefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic Craniopharyngioma2019

    • Author(s)
      Azuma M.、Khant Z.A.、Kitajima M.、Uetani H.、Watanabe T.、Yokogami K.、Takeshima H.、Hirai T.
    • Journal Title

      American Journal of Neuroradiology

      Volume: 41 Pages: 106-110

    • DOI

      10.3174/ajnr.a6359

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Journal Article] Impact of PCR-based molecular analysis in daily diagnosis for the patient with gliomas2018

    • Author(s)
      Yokogami Kiyotaka、Yamasaki Koji、Matsumoto Fumitaka、Yamashita Shinji、Saito Kiyotaka、Tacheva Asya、Mizuguchi Asako、Watanabe Takashi、Ohta Hajime、Takeshima Hideo
    • Journal Title

      Brain Tumor Pathology

      Volume: 35 Pages: 141-147

    • DOI

      10.1007/s10014-018-0322-3

    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Journal Article] 異型性脳室外神経細胞腫の1例2010

    • Author(s)
      松元文孝, 山下真治, 杉本哲朗, 盛口清香, 鮫島直樹, 丸塚浩助, 横上聖貴, 上原久生, 竹島秀雄
    • Journal Title

      脳神経外科速報

      Volume: 20 Pages: 1060-1065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Journal Article] Characteristics of tumour vessels in cytological squash smears of astrocytic tumours.2010

    • Author(s)
      Sato S, Sato Y, Marutsuka K, Takeshima H, Asada Y.
    • Journal Title

      Cytopathology in press

    • Data Source
      KAKENHI-PROJECT-20390387
  • [Journal Article] 異型性脳室外神経細胞腫の1例2010

    • Author(s)
      松元文孝、山下真治, 杉本哲朗, 盛口清香, 鮫島直樹, 丸塚浩助, 横上聖貴, 上原久生, 竹島秀雄
    • Journal Title

      脳神経外科速報 Vol.20(9)

      Pages: 1060-1065

    • Data Source
      KAKENHI-PROJECT-20390387
  • [Journal Article] Characteristics of tumour vessels in cytological squash smears of astrocytic tumours.2010

    • Author(s)
      Sato S, Sato Y, Marutsuka K, Takeshima H, Asada Y.
    • Journal Title

      Cytopathology

      Volume: (Epub(in press))

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Journal Article] Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.2009

    • Author(s)
      Fukushima T, Takeshima H, Kataoka H.
    • Journal Title

      Anticancer Res 29

      Pages: 4845-4854

    • Data Source
      KAKENHI-PROJECT-20390387
  • [Journal Article] Single nucleotide polymorphism 309 affects murin-double-minute 2 protein expression but not glioma tumorigenesis2007

    • Author(s)
      Tsuiki H, Takeshima H, et. al.
    • Journal Title

      Neurol Med Chir(Tokyo) 47

      Pages: 203-208

    • NAID

      110006274447

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Role of Kunitz domains in anti-invasive effect of hepatocyte growth factor activator inhibitor type 1 in human glioblastoma cells2007

    • Author(s)
      Miyata S, Takeshima H, et. al.
    • Journal Title

      Hum Cell 20

      Pages: 665-674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Clinical significance of ABCA2, a possiblemolecular marker for oligodendrogliomas2007

    • Author(s)
      Obara S, Takeshima H, et. al.
    • Journal Title

      Neurosurgery 60

      Pages: 707-714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Clinical significance of ABCA2, a possiblemolecular marker for oligodendrogliomas2007

    • Author(s)
      Obara, S., Nakata, M., Takeshima, H., Arita, Inagaki, N., Kuratsu, J
    • Journal Title

      Neurosurgery 60

      Pages: 707-714

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Single nucleotide polymorphism 309 affects murin-double-minute 2 protein expression but not glioma tumorigenesis.2007

    • Author(s)
      Tsuiki H, Takeshima H, et. al.
    • Journal Title

      Neurol Med Chir (Tokyo) 47

      Pages: 203-208

    • NAID

      110006274447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Role of Kunitz domains in anti-invasive effect of hepatocyte growth factor activator inhibitor type 1 in human glioblastoma cells2007

    • Author(s)
      Miyata, S., Fukushima, T., Kohama, K., Tanaka, H., Takeshima, H., Kataoka, H
    • Journal Title

      Hum Cell 20

      Pages: 100-106

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Clinical significance of ABCA2,a possiblemolecular marker for oligodendrogliomas2007

    • Author(s)
      Obara S, Takeshima H, et. al.
    • Journal Title

      Neurosurgery 60

      Pages: 707-714

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Role of Kunitz domains in anti-invasive effect of hepatocyte growth factor activator inhibitor type 1 in human glioblastoma cells2007

    • Author(s)
      Miyata S, Takeshima H, et. al.
    • Journal Title

      Human cell 20

      Pages: 100-106

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Single nucleotide polymorphism 309 affects murin-double-minute 2 protein expression but not glioma tumorigenesis2007

    • Author(s)
      Tsuiki, H., Nishi, T., Takeshima, H., Yano, S., Nakamura, H., Makino, K., Kuratsu, J
    • Journal Title

      Neurol Med Chir(Tokyo) 47

      Pages: 203-8

    • NAID

      110006274447

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Rising incidence of primary central nervous system lymphoma in kumamoto,Janan.2006

    • Author(s)
      Makiko K, Takeshima H, et. al.
    • Journal Title

      Surg Neurol 66

      Pages: 503-503

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Recurrent intracranial germinoma outside the initial radiation field:a single-institution study2006

    • Author(s)
      Nakamura H, Takeshima H, et. al.
    • Journal Title

      Acta Oncol 45

      Pages: 476-483

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Rising incidence of primary central nervous system lymphoma in Kumamoto, Japan2006

    • Author(s)
      Makino, K., Nakamura, H., Kino, T., Takeshima, H., Kuratsu, J
    • Journal Title

      Surg Neurol 66

      Pages: 503-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Recurrent intracranial germinoma outside the initial radiation field a single-institution study2006

    • Author(s)
      Nakamura, H., Takeshima, H., Makino, K., Kochi, M., Ushio, Y., Kurats, J
    • Journal Title

      Acta Oncol 45

      Pages: 476-483

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] The environment of increased concentration of docosahexaenoic acid in glioblastoma may suppress the anti-tumor effect of macrophages2005

    • Author(s)
      Hirano H, Takeshima H, et. al.
    • Journal Title

      Oncology Rep 13

      Pages: 1185-1191

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] C-kit expression in germinoma : An immunohistochemistry-based study2005

    • Author(s)
      Nakamura, H., Takeshima, H., Makino, K., Kuratsu, J
    • Journal Title

      J Neurooncol 75

      Pages: 163-167

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] C-kit expression in germinoma:An immunohistochemistry-based study2005

    • Author(s)
      Nakamura H, Takeshima H, et. al.
    • Journal Title

      J Neurooncol 75

      Pages: 163-167

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] The environment of increased concentration of docosahexaenoic acid in glioblastoma may suppress the anti-tumor effect of macrophages2005

    • Author(s)
      Hirano, H., Takeshima, H., Niiro, M., Nagayama, T., Oyoshi, T., Kuratsu, J
    • Journal Title

      Oncology Rep 13

      Pages: 1185-1191

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Journal Article] Integrin-linked kinase(ILK) regulation of the cell viability in PTEN mutant glioblastoma and in vitro inhibition by the specific COX-2 inhibitor NS-398.2004

    • Author(s)
      Obara S, Takeshima H, et al.
    • Journal Title

      Cancer Lett 208

      Pages: 115-122

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Expression of interleukin-6 in human craniopharyngiomas : A possible inducer of tumor-associated inflammation.2004

    • Author(s)
      Mori M, Takeshima H, et al.
    • Journal Title

      Int J Mol Med 14

      Pages: 505-509

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Combination electro-gene therapy using herpes virus TK and interluekin-12 expression plasmids is highly efficient against murine carcinomas, in vivo.2004

    • Author(s)
      Goto T, Takeshima H, et al.
    • Journal Title

      Mol Ther 10

      Pages: 929-937

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Expression and distribution of c-kit receptor and its ligand in human CNS germ cell tumors.2004

    • Author(s)
      Takeshima H et al.
    • Journal Title

      Brain Tumor Pathol 21

      Pages: 13-16

    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Integrin-linked kinase (ILK) regulation of the cell viability in PTEN mutant glioblastoma and in vitro inhibition by the specific COX-2 inhibitor NS-398.2004

    • Author(s)
      Obara S, Takeshima H et al.
    • Journal Title

      Cancer Lett 208

      Pages: 115-122

    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Expression and distribution of c-kit receptor and its ligand in human CNS germ cell tumors : a useful histological marker for the diagnosis of germinoma.2004

    • Author(s)
      Hideo Takeshima
    • Journal Title

      Brain Tumor Pathology 21

      Pages: 13-16

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370439
  • [Journal Article] Expression of interleukin-6 in human craniopharyngiomas : A possible inducer of tumor-associated inflammation.2004

    • Author(s)
      Mori M, Takeshima H et al.
    • Journal Title

      Int J Mol Med 14

      Pages: 505-509

    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Expression and distribution of c-kit receptor and its ligand in human CNS germ cell tumors.2004

    • Author(s)
      Takeshima H, et al.
    • Journal Title

      Brain Tumor Pathol 21

      Pages: 13-16

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Combination electro-gene therapy using herpes virus TK and interluekin-12 expression plasmids is highly efficient against murine carcinomas, in vivo.2004

    • Author(s)
      Goto T, Takeshima H et al.
    • Journal Title

      Mol Ther 10

      Pages: 929-937

    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Integrin-linked kinase (ILK) regulation of the cell viability in PTEN mutant glioblastoma and in vitro inhibition by the specific COX-2 inhibitor NS-398.2004

    • Author(s)
      Obara S, Takeshima H, et al.
    • Journal Title

      Cancer Lett 208

      Pages: 115-122

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] The expression of tissue factor correlates with proliferative ability in meningioma.2003

    • Author(s)
      Ishimaru K, Takeshima H, et al.
    • Journal Title

      Oncology Rep 10

      Pages: 1133-1137

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Journal Article] Combination of IL-12 and IL-18 of electro-gene therapy synergistically inhibits tumor growth.2003

    • Author(s)
      Tamura T, Takeshima H, et al.
    • Journal Title

      Anticancer Res 23

      Pages: 1173-1179

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591536
  • [Presentation] メチオニン代謝がglioma initiating cell(GIC)に及ぼす影響の解明2021

    • Author(s)
      横上聖貴、渡邉孝、武石剛、山下真治、中武康隆、竹島秀雄
    • Organizer
      第39回日本脳腫瘍病理学術集会
    • Data Source
      KAKENHI-PROJECT-19H03773
  • [Presentation] メチオニン代謝がglioma initiating cell(GIC)に及ぼす影響の解明2021

    • Author(s)
      横上聖貴、渡邉孝、武石剛、山下真治、中武康隆、竹島秀雄
    • Organizer
      日本脳神経外科学会第80回学術総会
    • Data Source
      KAKENHI-PROJECT-19H03773
  • [Presentation] Optic recessの偏位からみた頭蓋咽頭腫に対する手術到達法の選択2020

    • Author(s)
      渡邉 孝、上原久生、武石 剛、横上聖貴、竹島秀雄
    • Organizer
      第30回間脳下垂体腫瘍学会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] 高齢者髄膜腫の臨床的特徴と治療戦略2019

    • Author(s)
      渡邉 孝、斎藤清貴、山下真治、太田元、横上聖貴、竹島秀雄
    • Organizer
      日本脳神経外科学会 第78回学術総会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] Functional role of MYCN in SHH type TP53 mutated medulloblastoma’s metabolism.2019

    • Author(s)
      Yokogami K, Yamashita S, Saito K, Mizuguchi A, Watanabe T, Takeshima H
    • Organizer
      EANO 2019 meeting
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] 高齢者の非機能性下垂体腺腫に対する内視鏡下経鼻的経蝶形骨洞手術の視機能改善効果2019

    • Author(s)
      渡邉 孝、上原久生1)、武石 剛、横上聖貴、竹島秀雄
    • Organizer
      第32回日本老年脳神経外科学会, 第29回間脳下垂体腫瘍学会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] 高齢者下垂体腺腫に対する内視鏡下経鼻的経蝶形骨洞手術における視機能改善効果2019

    • Author(s)
      渡邉 孝、上原久生、武石 剛、横上聖貴、竹島秀雄
    • Organizer
      第29回間脳下垂体腫瘍学会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] Pilocytic astrocytomaのmicrovascular proliferation (MVP)は腫瘍由来の細胞を混じている2018

    • Author(s)
      山下真治、竹島秀雄他6名
    • Organizer
      第19回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-16K10763
  • [Presentation] 下垂体腺腫に対する経蝶形骨洞手術後の水・電解質管理2018

    • Author(s)
      渡邉 孝、外間洋平、武石 剛、竹島秀雄
    • Organizer
      第28回 日本間脳下垂体学会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] 小脳半球上部に発生した血管芽腫に対する手術戦略2018

    • Author(s)
      渡邉 孝、末松裕貴、松元文孝、齋藤清貴、水口麻子、山下真治、大田 元、 横上聖貴、竹島秀雄
    • Organizer
      第23回日本脳腫瘍の外科学会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] Cerebellar radiation-induced glioma after complete remission of pineal tumor2018

    • Author(s)
      Tomohiro Kawano, Takashi Watanabe, Kiyotaka Yokogami, Tsuyoshi Fukushima, Hideaki Yokoo, Hideo Takeshima
    • Organizer
      第36回日本脳腫瘍病理学会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] Visual outcome after endoscopic endonasal transsphenoidal surgery for nonfunctioning pituitary adenomas in elderly patients2018

    • Author(s)
      Takashi Watanabe, Hisao Uehara, Go Takeishi, Kiyotaka Yokogami,Hideo Takeshima
    • Organizer
      The 15th KYUSHU and Young-Honam Neurosurgical Joint Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] 高齢者における下垂体腺腫に対する内視鏡下経鼻的経蝶形骨洞手術の治療成績2018

    • Author(s)
      渡邉 孝、武石 剛、上原久生、竹島秀雄
    • Organizer
      日本脳神経外科学会 第77回学術総会
    • Data Source
      KAKENHI-PROJECT-16K10764
  • [Presentation] Detection of p53 mutations in glioblastoma multiforme2016

    • Author(s)
      Takeshima H, Kawasoe T, Yamashita S, Mizuguchi S, Fukushima T, Yokogami K, Yamasaki K
    • Organizer
      13th Asian society for neuro-oncology meeting
    • Place of Presentation
      Sydney, Australlia
    • Year and Date
      2016-09-11
    • Data Source
      KAKENHI-PROJECT-16K10763
  • [Presentation] マウス神経幹細胞とグリオーマ幹細胞におけるEvi1の機能解析2013

    • Author(s)
      横上聖貴、水口惣平、水口麻子、 山崎浩司、竹島秀雄
    • Organizer
      第31回日本脳腫瘍学会学術集会
    • Place of Presentation
      フェニックスシーガイアリゾート(宮崎県宮崎市)
    • Data Source
      KAKENHI-PROJECT-25462275
  • [Presentation] グリオーマ細胞の脱分化、増殖におけるP13KとTGF-betaの役割2010

    • Author(s)
      池田俊勝、横上聖貴、山下真治、武石剛、上原久生、竹島秀雄
    • Organizer
      日本脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] P13K but no TGF-beta regulates dedifferentiation and proliferation of glioma cells2010

    • Author(s)
      池田俊勝, 横上聖貴, 山下真治, 武石剛, 上原久生, 竹島秀雄
    • Organizer
      The 7th Meeting of asian society for neuro-oncology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] 中枢神経細胞腫における初代培養の試み2010

    • Author(s)
      武石剛、横上聖貴、池田俊勝、山下真治、上原久生、竹島秀雄
    • Organizer
      日本脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] 中枢神経細胞腫における初代培養の試み2010

    • Author(s)
      横上聖貴、武石剛、池田俊勝、山下真治、上原久生、竹島秀雄
    • Organizer
      第11回日本分子脳神経外科学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] グリオーマ細胞の脱分化、増殖におけるP13KとTGF-betaの役割2010

    • Author(s)
      池田俊勝、横上聖貴、山下真治、武石剛、上原久生、竹島秀雄
    • Organizer
      第11回日本分子脳神経外科学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] P13K but no TGF-beta regulates dedifferentiation and proliferation of glioma cells2010

    • Author(s)
      Ikeda T, Yokogami K.Yamashita S, Takeishi G, Uehara H.Takeshima H
    • Organizer
      The 7^<th>Meeting of asian society for neuro-oncology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-06-10
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] Establishment of stem-like cell of central neurocytoma.2010

    • Author(s)
      武石剛, 横上聖貴, 池田俊勝, 山下真治, 上原久生, 竹島秀雄
    • Organizer
      The 7th Meeting of asian society for neuro-oncology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] Establishment of stem-like cell of central neurocytoma.2010

    • Author(s)
      Takeishi G, Yokogami K, Ikeda T, Yamashita S, Uehara H, Takeshima H
    • Organizer
      The 7^<th> Meeting of asian society for neuro-oncology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-06-10
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] 人脳腫瘍サンプルと市販脳腫瘍細胞株からのcancer stem-like cell (CSC) lineの樹立と性格2009

    • Author(s)
      横上聖貴、上原久生、武石 剛、山下真治、池田俊勝、竹島秀雄
    • Organizer
      第10回日本分子脳神経外科学会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] ヒト脳腫瘍sampleからのcancer stem-like cell (CSC) lineの樹立2009

    • Author(s)
      横上聖貴、上原久生、武石 剛、山下真治、池田俊勝、竹島秀雄
    • Organizer
      第27回日本脳腫瘍学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390387
  • [Presentation] Clinical singnificance of ABCA2,a movel molecular marker for oligodendroglioma2007

    • Author(s)
      Takeshima H
    • Organizer
      The 5th Meeting of the Asian Society for Neuro-Oncology
    • Place of Presentation
      Istanbul
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Clinical significance of ABCA2, a novel molecular marker for oligodendroglioma2007

    • Author(s)
      Hideo, Takeshima, So-ichi, Obara, Jun-ichi, Kuratsu
    • Organizer
      The 5th Meeting of the Asian Society for Neuro-Oncology
    • Place of Presentation
      Istanbul
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Neoadjuvant therapy of germ cell tumor and novel tumor marker for germinoma2007

    • Author(s)
      Takeshima, H
    • Organizer
      Catholic International Neurosurgery Update
    • Place of Presentation
      Seoul
    • Year and Date
      2007-02-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Clinical significance of ABCA2, a novel molecular marker for oligodendroglioma.2007

    • Author(s)
      Takeshima H
    • Organizer
      The 5th Meeting of the Asian Society for Neuro-Oncology
    • Place of Presentation
      Istanbul
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Neoadiuvant theraphy of germ cell tumor and novel tumor marker for germinoma2007

    • Author(s)
      Takeshima H
    • Organizer
      Catholic International Neurosurgery Update
    • Place of Presentation
      Seoul
    • Year and Date
      2007-02-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Clinical significance of ABCA2,a novel molecular marker for Oligodendroglioma2006

    • Author(s)
      Takeshima H
    • Organizer
      2006 International Brain Tumor Research and Therapy Meeting
    • Place of Presentation
      Napa Valley.California
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Clinical significance of ABCA2, a novel molecular marker, for Oligodendroglioma2006

    • Author(s)
      Takeshima, H., Obara, S., Kuratsu, J
    • Organizer
      2006 International Brain Tumor Research and Theraov Meeting
    • Place of Presentation
      Silverado Resort, Napa Valley, California
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Coexpression of c-kit and SCF in CNS germ cell tumors2005

    • Author(s)
      Takeshima, H., Uchida, H., Yunoue, S., Nakamura, H., Kuratsu, J
    • Organizer
      The 2nd International CNS GCT Symposium
    • Place of Presentation
      Hilton LosAngeles
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • [Presentation] Coexpression of c-kit and SCF germ cell tumors2005

    • Author(s)
      Takeshima H
    • Organizer
      The 2nd International CNF GCT Symposium
    • Place of Presentation
      Hilton Los Angeles
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390405
  • 1.  KURATSU Junichi (20145296)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 8 results
  • 2.  NISHI Tohru (00264309)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 3.  KOCHI Masato (70178218)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 4.  USHIO Yukitaka (20028583)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 5.  YOKOGAMI Kiyotaka (40284856)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 29 results
  • 6.  YAMASHITA Shinji (40468046)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 21 results
  • 7.  HIRANO Hirofumi (00264416)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 8.  Watanabe Takashi (90573337)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 9.  MIZUGUCHI Asako (00647472)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 10.  SAYA Hideyuki (80264282)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  UEHARA Hisao (80203470)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 12.  MORIYAMA Takuzo (50239703)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  YOKOYAMA Shunichi (90191519)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  NIIRO Masaki (30172612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  MIZUGUCHI Souhei (50398103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  MORISHITA Kazuhiro (80260321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HAMADA Junichiro (40253752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NAKANO Masahiro (40002125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SAITO Yoshiki (50304994)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKAMURA Hideo (30359963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  IMAMURA Shinichi (60315439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NAGAYAMA Tetsuya (40336334)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  片桐 千秋 (00443664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  石内 勝吾 (10312878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  菅原 健一 (50375573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SUGIMOTO Yoshikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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