MORISHITA Kazuhiro 森下和広

… Alternative Names

森下和廣モリシタカズヒロ

森下和弘モリシタカズヒロ

森下和広モリシタカズヒロ

森下和宏モリシタカズヒロ

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Researcher Number	80260321
Other IDs
Affiliation (Current)	2022: 宮崎大学, フロンティア科学総合研究センター, 特別教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 宮崎大学, フロンティア科学総合研究センター, 特別教授 2004 – 2020: 宮崎大学, 医学部, 教授 2016: 宮崎大学, 医学部腫瘍生化学分野, 教授 2014: 宮崎大学, 医学部機能制御学講座腫瘍生化学分野, 教授 2002 – 2003: 宮崎医科大学, 医学部, 教授 … More 1996: National Inst of Cancer Research, Section Head, 室長 1994 – 1996: 国立がんセンター研究所, 主任研究官 1994 – 1996: 国立がんセンター研究所, 生物学部, 主任研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Pathological medical chemistry / Hematology / Tumor biology / Medical genome science / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Hematology / Biological Sciences / Urology / Morphological basic dentistry … More / Pediatrics / Neurosurgery / Hematology / Tumor therapeutics / Pathological medical chemistry / Basic Section 50010:Tumor biology-related / Basic Section 56040:Obstetrics and gynecology-related Less
Keywords	Principal Investigator ATL / EVI1 / NDRG2 / 成人T細胞白血病 / HTLV-1 / 転写因子 / TSLC1 / GATA-2 / 接着因子 / Integrin … More / 成人T細胞白血病(ATL) / 癌 / ATLL / 造血幹細胞 / 白血病幹細胞 / DNAマイクロアレイ / ITGA6 / ITGB4 / がん幹細胞 / アセチル化修飾 / EVIl / TSLC1/CADM1/IgSF4 / TCF8(ZEB1) / BCL11B / 遺伝子 / ゲノム / TCF8/ZEB1 / CADM1 / IgSF4 / TCF8 / ZEB1 / 接着依存性薬剤耐性(CAM-DR) / Zinc finger protein / Laminin / 接着存性薬剤耐性(CAM-DR) / 発生分化 / 造血 / 神経 / 分化 / MEL1/EVI1 / 骨軟骨分化 / MEL1/PRDM16 / PTEN / NF-kB / NIK / 感染防御 / リン酸化異常 / ゲノム異常 / がん / IGSF4 / がん抑制遺伝子 / cancer / 腸内細菌叢 / PRMT5 / HSP90 / アルギニンメチル化 / PP2A / sythethic lethality / HTLV1 / client protein / 感染症 / ペルー / 糞線虫症 / 腸内細菌 / 糞線虫 / ゲノム解析 / 日和見感染 / 重複感染症 / 感染 / 代謝異常 / PKM1/M2 / AMPK … More Except Principal Investigator 白血病 / 癌 / EVI1 / 蛍光標識PCR-SSCP法 / 軟部悪性腫瘍 / がん遺伝子EVI-1 / △FosB / がん抑制遺伝子WT1 / がん遺伝子c-erbB-2 / 転写因子 / GIG-1 / Evi-1 / MEL1S / GATA-2 / HDAC / TSA / leukemogenesis / MEL1 (PRDM16) / HTLV-1 / Zink finger / 癌の遺伝子診断 / 消化器癌 / 肺癌 / 神経芽腫 / 遺伝子診断 / 癌遺伝子 / 癌抑制遺伝子 / hMTH1 / EVI-1 / Kid / p53 / 尿路腫瘍 / 平滑筋肉腫 / 転写因子YB-1 / 蛍光PCR-SSCP法 / ゲノム / 悪性リンパ腫 / アレーCGH / トランスレーショナルリサーチ / マイクロアレー / 遺伝子 / トランスレーショナリサーチ / MALTリンパ腫 / MALT1 / API2 / API2-MALT1 / GATA-1 / 血球分化 / 小Maf群因子 / MAT1 / 前立腺 / シグナル伝達 / 前立腺癌 / caveolin / タンパク質 / 蛋白質 / 骨分化 / 家族性 / 胚細胞変異 / ETV6遺伝子 / 急性白血病 / アレイCGH / 発現アレイ / エクソーム解析 / 急性リンパ性白血病 / 発現プロファイル / 次世代シークエンサー / EGFR / neural precurser cell / glioma / glioma initiating cell / NOTCH / GIC / integrin / laminin / Notch / VEGF / 転写制御因子 / 分化停止機構 / 好中球 / NK細胞 / PEBP2α / PEBP2β / GIG-1タンパク / アルカリフォスファターゼ / Evi-1遺伝子 / GATA遺伝子 / ETS遺伝子 / 慢性骨髄性白血病細胞 / TF-1細胞 / IFN-α抵抗性 / 骨髄細胞分化マーカー / GIG-1蛋白 / 好中球系細胞 / BCR / ABL遺伝子 / 転写活性因子 / transcriptional factor / maturation arrest / neutrophil / NK cell / PEBP2 alpha / PEBP2 beta / EVI1欠損マウス / 造血幹細胞 / 白血病発症機構 / t(3;3)転座 / PCAF / トリコスタチンA / Mice lacking EVI1 / Hematopoietic stem cells / t(1;3)転座 / MEL1(PRDM16) / 発症機構 / 発現制御 / t(1 : 3) translocation / GATA-2 gene regulation / 免疫遺伝子療法 / キメラ抗原受容体 / T細胞 / 造血器腫瘍 / 遺伝子治療 / 成人T細胞白血病 / 免疫療法 / T細胞療法 / NADDPH oxidase(Nox) / 分子腫瘍学 / 活性酸素 / HLV-1 / すい臓がん / NADPH oxidase (Nox) / NADPH oxidase(Nox) / Nox / Exosome / ATL / CADM1 / HTLV-1 Tax / NF-kB / p47 / CAV1 / prostate cancer / HTLV-I Tax / TSLC1 / TFR1 / Tax / TFR / BLV / 牛白血病 / バイオマーカー / EBL / サイトメガロウイルス / CMV IgG avidity / 先天性サイトメガロウイルス感染症 / 妊婦スクリーニング / ELISPOTアッセイ Less

Mechanism of Adult T-Cell Leukemia Development Dependent on Metabolic Aberration Caused by NDRG2 DeficiencyPrincipal Investigator
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  University of Miyazaki
低侵襲・効率的な胎内サイトメガロウイルス感染症診断のための新たなアルゴリズム開発
- Principal Investigator
  
  金子政時
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  University of Miyazaki
Comparative analysis of tumorigenesis by HTLV-1 and BLV
- Principal Investigator
  
  Tani Chikako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  University of Miyazaki
Dysregulation of stress signaling leading to oncogenesis by NDRG2-deficicencyPrincipal Investigator
- Principal Investigator
  
  Morishita Kazuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  University of Miyazaki
Comparative genomic analysis of high frequent ATL development due to HTLV-1 superinfection in PeruPrincipal Investigator
- Principal Investigator
  
  Morishita Kazuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  University of Miyazaki
The study on the regulatory mechanism of NADPH oxidase (Nox) 5alpha and 4 redox signaling involved in cancer development
- Principal Investigator
  
  Kamata Tohru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
Analysis of ATL development dependent on abnormalities of intestinal floraPrincipal Investigator
- Principal Investigator
  
  Morishita Kazuhiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
EVI1・MEL1ファミリーによる細胞運命決定能Principal Investigator
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
Analysis of ATL leukemogenesis through breakage of defense mechanism of HTLV-1 infectionPrincipal Investigator
- Principal Investigator
  
  Kazuhiro Morishita
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
Identification of causative genes in familial acute lymphoblastic leukemia
- Principal Investigator
  
  Moritake Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Miyazaki
Function of Ecotropic Viral Integration Site 1 (EVI1) gene in neural precurser cells and human glioma cells
- Principal Investigator
  
  Kiyotaka Yokogami
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Miyazaki
Development of immunogene therapy using T-cells expressing a chimeric antigen receptor for adult T-cell leukemia
- Principal Investigator
  
  Tsukahara Tomonori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Jichi Medical University
The pathological analysis of ATL with a focus on exosomal secreting protein superfamily (CADM1/CAV1)
- Principal Investigator
  
  Nishikata Ichiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University of Health and Welfare
  University of Miyazaki
Search for a new target therapy in the advanced prostate cancer
- Principal Investigator
  
  KAMOTO Toshiyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Miyazaki
Investigation of MEL1/PRDM16 function in bone differentiation
- Principal Investigator
  
  IGAWA Kaori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  University of Miyazaki
ＥＶＩ１は造血及び神経幹細胞の運命を制御するPrincipal Investigator
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
Molecular analysis of leukemogenesis of adult-T cell leukemia by genomic abnormalitiesPrincipal Investigator
- Principal Investigator
  
  MORISHITA Kazuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
細胞接着能を標的としたEVI1高発現白血病治療法の開発Principal Investigator
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  University of Miyazaki
Evi1遺伝子群による細胞接着を介した白血病幹細胞維持機構の解明Principal Investigator
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
Tumor suppressor in lung cancer-1 gene, TSLC1, has an oncogenic potential inAdult T-cell leukemiaPrincipal Investigator
- Principal Investigator
  
  MORISHITA Kazuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
analysis of leukemogenesis by MELS in MEL-EVI1 gene family
- Principal Investigator
  
  NISHIKATA Ichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Miyazaki
EVI1遺伝子群によるGATA2転写制御と白血病発症機構の解析Principal Investigator
- Principal Investigator
  
  森下和広
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Miyazaki
analysis of leukemogenesis by the expression of EVI1/MEL1S, the PR domain-defective proteins, in EVI1/MEL1 gene family
- Principal Investigator
  
  NISHIKATA Ichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Miyazaki
転座関連遺伝子及び転写因子による細胞分化とがん化の分子機構
- Principal Investigator
  
  瀬戸加大
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Cancer Center Research Institute
転写制御遺伝子群の発癌への関与
- Principal Investigator
  
  林健志
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
転写制御遺伝子群の発癌への関与
- Principal Investigator
  
  林健志
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
転写制御遺伝子群の発癌への関与
- Principal Investigator
  
  林健志
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
がんの遺伝子診断
- Principal Investigator
  
  珠玖洋
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Molecular Analysis of Maturation Arrest Mechanism of Myeloid Leukemogenesis
- Principal Investigator
  
  ASANO Shigetaka
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

[Book] HTLV-1と疾患2007
- Author(s)
  森下和広, 他
- Total Pages
  257
- Publisher
  文公堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Book] HTLV-1と疾患2007
- Author(s)
  森下和広
- Total Pages
  263
- Publisher
  文公堂
- Data Source
  KAKENHI-PROJECT-18590302
[Journal Article] Clinical significance of soluble CADM1 as a novel marker for adult T-cell leukemia/lymphoma.2020
- Author(s)
  Nakahata S, et al, Saito M, Morishita K.
- Journal Title
  
  Haematologica
  
  Volume: 105 Pages: 1-1
- DOI
  10.3324/haematol.2019.234096
- Description
  in Press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H03594, KAKENHI-PROJECT-17H04600, KAKENHI-PROJECT-17K09931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20K08715
[Journal Article] Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells2020
- Author(s)
  Ichikawa T, Shanab O, Nakahata S, Shimosaki S, Manachai N, Ono M, Iha H, Shimoda K, Morishita K
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1867 Pages: 118615-118615
- DOI
  10.1016/j.bbamcr.2019.118615
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H04600, KAKENHI-PROJECT-17K09931, KAKENHI-PROJECT-18K07238
[Journal Article] CGRP-CRLR/RAMP1 signal is important for stress-induced hematopoiesis2019
- Author(s)
  Suekane A, Saito Y, Nakahata S, Ichikawa T, Ogoh H, Tsujikawa K, Morishita K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 429-429
- DOI
  10.1038/s41598-018-36796-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07238, KAKENHI-PROJECT-17H03581
[Journal Article] The expression of cell adhesion molecule 1 and its splicing variants in Sezary cells and cell lines from cutaneous T-cell lymphoma.2019
- Author(s)
  Yamaguchi Mari、Morizane Shin、Hamada Toshihisa、Miyake Tomoko、Sugaya Makoto、Iwata Hiroaki、Fujii Kazuyasu、Haramoto‐Shiratsuki Rie、Nakagawa Yuki、Miura Mayumi、Ohshima Koichi、Morishita Kazuhiro、Takahashi Takahide、Imada Masahide、Okada Ken、Uehara Jiro、Sowa‐Osako Junko、Iwatsuki Keiji
- Journal Title
  
  J Dermatol.
  
  Volume: 46 Pages: 967-977
- DOI
  10.1111/1346-8138.15078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08777, KAKENHI-PROJECT-17H03581
[Journal Article] Overexpression of absent in melanoma 2 in oral squamous cell carcinoma contributes to tumor progression2019
- Author(s)
  Nakamura Y, Nakahata S, Kondo Y, Izumi A, Yamamoto K, Ichikawa T, Tamura T, Noumi K, Yamashita Y, Morishita K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 509 Pages: 82-82
- DOI
  10.1016/j.bbrc.2018.12.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07238, KAKENHI-PROJECT-17H03581
[Journal Article] Direct-Injection Electron Ionization-Mass Spectrometry Metabolomics Method for Analyzing Blueberry Leaf Metabolites That Inhibit Adult T-cell Leukemia Proliferation2019
- Author(s)
  Kai Hisahiro、Uesawa Yoshihiro、Kunitake Hisato、Morishita Kazuhiro、Okada Yoshihito、Matsuno Koji
- Journal Title
  
  Planta Med
  
  Volume: 85 Pages: 81-87
- DOI
  10.1055/a-0725-8295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15474, KAKENHI-PROJECT-17H03581
[Journal Article] The regulation of NDRG2 expression during ATLL development after HTLV-1 infection2019
- Author(s)
  Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.
- Journal Title
  
  Biochim Biophys Acta, Mol Basis Disease
  
  Volume: 1865 Pages: 2633-2646
- DOI
  10.1016/j.bbadis.2019.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07238, KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H04600, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K09931
[Journal Article] Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB2019
- Author(s)
  Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 1-14
- DOI
  10.1038/s41598-019-39424-7
- NAID
  120006825908
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07238, KAKENHI-PROJECT-16K07120, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K09931, KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H04600
[Journal Article] Suppression of GPR56 expression by pyrrole-imidazole polyamide represents a novel therapeutic drug for AML with high EVI1 expression.2018
- Author(s)
  Saha Hasi Rani、Kaneda-Nakashima Kazuko、Shimosaki Shunsuke、Suekane Akira、Sarkar Bidhan、Saito Yusuke、Ogoh Honami、Nakahata Shingo、Inoue Kentaro、Watanabe Takayoshi、Nagase Hiroki、Morishita Kazuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 1-12
- DOI
  10.1038/s41598-018-32205-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07323, KAKENHI-PROJECT-17H03602, KAKENHI-PROJECT-17H03581
[Journal Article] BCL11B is frequently downregulated in HTLV-1-infected T-cells through Tax-mediated proteasomal degradation2017
- Author(s)
  Permatasari H., Nakahata S., Ichikawa T., Morishita K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 490 Pages: 1086-1092
- DOI
  10.1016/j.bbrc.2017.06.172
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Journal Article] SWAP-70 contributes to spontaneous transformation of mouse embryo fibroblasts.2016
- Author(s)
  Chang YT, Shu CL, Lai JY, Ching-Yu L, Chuu CP, Morishita K, Ichikawa T, Jessberger R, Fukui Y.
- Journal Title
  
  Exp Cell Res
  
  Volume: 15 Pages: 30020-3
- DOI
  10.1016/j.yexcr.2015.06.011
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15087, KAKENHI-PROJECT-15K08310
[Journal Article] Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo2015
- Author(s)
  Okuma K, Hiyoshi M, Tateyama S, Takizawa K, Saito M, Kuramitsu M, Araki K, Morishita K, Okada S, Yamamoto N, Biragyn A, Yamaguchi K, Hamaguchi I.
- Journal Title
  
  Retrovirology.
  
  Volume: 12 Pages: 1-14
- DOI
  10.1186/s12977-015-0199-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08439, KAKENHI-PROJECT-15K09462, KAKENHI-PROJECT-15K15087, KAKENHI-PROJECT-25293081
[Journal Article] The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.2015
- Author(s)
  Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.
- Journal Title
  
  Cell Signal.
  
  Volume: 27 Pages: 2087-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15087
[Journal Article] The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of AKT and GSK3β2015
- Author(s)
  Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.
- Journal Title
  
  Cell Signal.
  
  Volume: 27 Pages: 2087-2098
- DOI
  10.1016/j.cellsig.2015.07.012
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08310, KAKENHI-PROJECT-25430113, KAKENHI-PROJECT-25293081
[Journal Article] Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development2015
- Author(s)
  Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Pages: 12841-12841
- DOI
  10.1038/srep12841
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08310, KAKENHI-PROJECT-15K15087, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-25430113, KAKENHI-PROJECT-25293081
[Journal Article] Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype2015
- Author(s)
  Shigemura T, Shiohara M, Kato M, Furuta S, Kaneda K, Morishita K, Hasegawa H, Fujii M, Gorlach A, Koike K, Kamata T.
- Journal Title
  
  J Virol
  
  Volume: 89 Pages: 9080-9
- DOI
  10.1128/jvi.00983-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15087, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-15K21133
[Journal Article] Maintenance of leukemic and normal hematopoietic stem cells in bone marrow niches by EVI1-regulated GPR562015
- Author(s)
  Saito Y, Morishita K
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 56 Issue: 4 Pages: 375-375
- DOI
  10.11406/rinketsu.56.375
- NAID
  130005069844
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293081
[Journal Article] Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers2014
- Author(s)
  Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, Manachai N, Yamakawa N, Hamasaki M, Kitabayashi I, Arai Y, Kanai Y, Taki T, Abe T, Kiyonari H, Shimoda K, Ohshima K, Horii A, Shima H, Taniwaki M, Yamaguchi R, Morishita K.
- Journal Title
  
  Nature Communications
  
  Volume: in press Pages: 1-15
- DOI
  10.1038/ncomms4393
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590452, KAKENHI-PROJECT-24591407, KAKENHI-PROJECT-24591928, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-25430113, KAKENHI-PROJECT-25860242, KAKENHI-PROJECT-26430130
[Journal Article] Development of a complete human anti-human transferrin receptor C antibody as a novel marker of oral dysplasia and oral cancer.2014
- Author(s)
  5.Nagai K, Nakahata S, Shimosaki S, Tamura T, Kondo Y, Baba T, Taki T, Taniwaki M, Kurosawa G, Sudo Y, Okada S, Sakoda S, Morishita K
- Journal Title
  
  Cancer Medicine
  
  Volume: 3 Pages: 1085-1099
- DOI
  10.1002/cam4.267
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-25430113
[Journal Article] Increased plasma lactoferrin levels in leucocytapheresis therapy in patients with rheumatoid arthritis.2014
- Author(s)
  Miyauchi S, Umekita K, Hidaka T, Umeki K, Aratake Y, Takahashi N, Sawaguchi A, Nakatake A, Morinaga I, Morishita K, Okayama A.
- Journal Title
  
  Rheumatology (Oxford).
  
  Volume: 53 Pages: 1966-72
- DOI
  10.1093/rheumatology/keu219
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081
[Journal Article] Delta-tocotrienol induces apoptotic cell death via depletion of intracellular squalene in ED40515 cells.2014
- Author(s)
  M. Yamasaki, M. Nishinura, Y. Sakakibara, M. Suiko, K. Morishita, K. Nishiyama.
- Journal Title
  
  Food Funct.
  
  Volume: 5 Pages: 2842-2849
- DOI
  10.1039/c4fo00635f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580193, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081
[Journal Article] PP2A inactivation by ROS accumulation2014
- Author(s)
  Nakahata S, Morishita K.
- Journal Title
  
  Blood
  
  Volume: 124 Pages: 2163-2165
- DOI
  10.1182/blood-2014-08-594093
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-25430113
[Journal Article] In vitro and in vivo safety and efficacy studies of amphotericin B on Babesia gibsoni.2014
- Author(s)
  Masahiro Yamasaki, Eriko Harada, Yu Tamura, Sue Yee Lim, Tatsuyuki Ohsuga, Nozomu Yokoyama, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
- Journal Title
  
  Vet Parasitol.
  
  Volume: 205 Pages: 424-33
- DOI
  10.1016/j.vetpar.2014.09.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580456, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081
[Journal Article] Oligomeric proanthocyanidins from rabbiteye blueberry leaves inhibits the proliferation of human T-cell lymphotropic virus type 1-associated cell lines via apoptosis and cell cycle arrest2014
- Author(s)
  Kiyoko Nagahama, Nozomu Eto, Yoichi Sakakibara, Yoh-ichi Matsusita, Kazuhiro Sugamoto, Kazuhiro Morishita, Masahito Suiko
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 6 Pages: 356-366
- DOI
  10.1016/j.jff.2013.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593368, KAKENHI-PROJECT-25293081
[Journal Article] Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell in filtrationin to multiple organs and improves survival period for ATL model mice2013
- Author(s)
  Ikebe E, Kawaguchi A, Tezuka K, et al
- Journal Title
  
  Blood Cancer J
  
  Volume: 3
- DOI
  10.1038/bcj.2013.30
- NAID
  120006986112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590641, KAKENHI-PROJECT-24590562, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-25460461, KAKENHI-PROJECT-25860729
[Journal Article] Genistein induces apoptotic cell death associated with inhibition of the NF-κB pathway in adult T-cell leukemia cells2013
- Author(s)
  Masao Yamasaki, Yoshihiro Mine, Misato Nishimura, Satoshi Fujita, Yoichi Sakakibara, Masahito Suiko, Kazuhiro Morishita and Kazuo Nishiyama
- Journal Title
  
  Cell Biol Int.
  
  Volume: 37 Pages: 742-747
- DOI
  10.1002/cbin.10101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580174, KAKENHI-PROJECT-24580193, KAKENHI-PROJECT-25293081
[Journal Article] Increased Plasma Caveolin-1 Levels Are Associated with Progression of Prostate Cancer among Japanese Men.2013
- Author(s)
  Sugie S, Mukai S, Tsukino H, Toda Y, Yamauchi T, Nishikata I, Kuroda Y, Morishita K, Kamoto T
- Journal Title
  
  Anticancer Res
  
  Volume: 33（5） Pages: 1893-1897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592398
[Journal Article] Suppressed expression of NDRG2 correlates with poor prognosis in pancreatic cancer.2013
- Author(s)
  Yamamura A, et al
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 441(1) Pages: 102-107
- DOI
  10.1016/j.bbrc.2013.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253, KAKENHI-PROJECT-23590452, KAKENHI-PROJECT-24590471, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-25462673
[Journal Article] Increased plasma caveolin-1 levels are associated with progression of prostate cancer among Japanese men.2013
- Author(s)
  Sugie S, Mukai S, Tsukino H, Toda Y, Yamauchi T, Nishikata I, Kuroda Y, Morishita K, Kamoto T.
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 1893-7
- DOI
  10.1007/s12032-011-9934-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118720
[Journal Article] Genistein induces apoptotic cell death associated with inhibition of the NF-κB pathway in adult T-cell leukemia cells.2013
- Author(s)
  Yamasaki M, Mine Y, Nishimura M, Fujita S, Sakakibara Y, Suiko M, Morishita K, Nishiyama K.
- Journal Title
  
  Cell Biol Int.
  
  Volume: 37 Pages: 742-7
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118720
[Journal Article] Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56.2013
- Author(s)
  Saito Y., Kaneda K., Suekane A., Ichihara E., Nakahata S., Yamakawa N., Nagai K., Mizuno N., Kogawa K., Miura I., Itoh H., and Morishita K..
- Journal Title
  
  Leukemia.
  
  Volume: 27 Pages: 1-11
- DOI
  10.1038/leu.2013.75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590113, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PUBLICLY-23118523, KAKENHI-PUBLICLY-23121522
[Journal Article] The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1 Leukemia2012
- Author(s)
  Yamakawa N, Kaneda K, Saito Y, Ichihara E, Morishita K
- Journal Title
  
  PLoS One
  
  Volume: 7(1)
- DOI
  10.1371/journal.pone.0030706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Clinical significance of CADM1/TSLC1/IgSF4 expression in adult T-cell leukemia/lymphoma.2012
- Author(s)
  Nakahata S, Saito Y, Marutsuka K, Hidaka T, Maeda K, Hatakeyama K, Shiraga T, Goto A, Takamatsu N, Asada Y, Utsunomiya A, Okayama A, Kubuki Y, Shimoda K, Ukai Y, Kurosawa G, Morishita K
- Journal Title
  
  Leukemia
  
  Volume: Jan;26 (6) Pages: 1238-1246
- DOI
  10.1038/leu.2011.379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PROJECT-22590532, KAKENHI-PROJECT-23591397
[Journal Article] Defective human T-lymphotropic viras type 1 provirus in asymptomatic carriers2011
- Author(s)
  Takenouchi H, Umeki K, Sasaki D, Yamamoto I, Nomura H, Takajo I, Ueno S, Umekita K, Kamihira S, Morishita K, and Okayama A
- Journal Title
  
  Int J Cancer
  
  Volume: 128 Pages: 1335-43
- DOI
  10.1002/ijc.25450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PROJECT-21390182
[Journal Article] Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation2011
- Author(s)
  Nishikata I, Nakahata S, Saito Y, Kaneda K, Ichihara E, Yamakawa N, and Morishita K
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 196-207
- DOI
  10.1038/onc.2011.132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PUBLICLY-23118523
[Journal Article] Angiopoietin1 contributes to the maintenance of cell quiescence in EVI1 high leukemia cells2011
- Author(s)
  Ichihara E, Kaneda K, Saito Y, Yamakawa N, Morishita K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 416 Pages: 239-45
- URL
  http://dx.doi.org/10.1016/j.bbrc.2011.10.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] CD52 as a molecular target for immunotherapy to treatacute myeloid leukemia with high EVI1 expression2011
- Author(s)
  Saito Y, Nakahata S, Yamakawa N, Kaneda K, Ichihara A, Suekane A, and Morishita K
- Journal Title
  
  Leukemia
  
  Volume: 25 Pages: 21-931
- DOI
  10.1038/leu.2011.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PUBLICLY-23118523
[Journal Article] NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma.2010
- Author(s)
  Furuta, H., Kondo, Y., Nakahata, S., Hamasaki, M., Sakoda, S., Morishita, K
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 391 Pages: 1785-1791
- URL
  http://dx.doi.org/10.1016/j.bbrc.2009.12.156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma2010
- Author(s)
  Nakahata, S., Yamazaki, H., Nakauchi, H., Morishita, K
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 4157-4159
- DOI
  10.1038/onc.2010.172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PROJECT-22659058
[Journal Article] Involvement of LKB1 in epithelial-mesenchymal transition(EMT) of human lung cancer cells2010
- Author(s)
  Roy BC, Kohno T, Iwakawa R, Moriguchi T, Kiyono T, Morishita K, Sanchez-Cespedes M, Akiyama T, Yokota J
- Journal Title
  
  Lung Cancer
  
  Volume: 70 Pages: 136-4
- URL
  http://dx.doi.org/10.1016/j.lungcan.2010.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Downregulation of CDKN1A in adult T-cell leukemia/lymphoma despite overexpression of CDKN1A in human T-lymphotropic virus 1-infected cell lines2010
- Author(s)
  Watanabe, M., Nakahata, S., Hamasaki, M., Saito, Y., Kawano, Y., Hidaka, T., Yamashita, K., Umeki, K., Taki, T., Taniwaki, M., Okayama, A., Morishita, K
- Journal Title
  
  J. Virol
  
  Volume: 84 Pages: 6966-6977
- DOI
  10.1128/jvi.00073-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA22010
- Author(s)
  Shimahara A, Yamakawa N, Nishikata I, Morishita K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 16967-16977
- DOI
  10.1074/jbc.m110.102046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Genistein Induced Apoptotic Cell Death in Adult T-Cell Leukemia Cells through Estrogen Receptors2010
- Author(s)
  Yamasaki M, Mukai A, Ohba M, Mine Y, Sakakibara Y, Suiko M, Morishita K, Nishiyama K
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 74 Pages: 2113-5
- NAID
  10027560823
- URL
  http://dx.doi.org/10.1271/bbb.100359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Multiple integrations of human T-lymphotropic virus type 1 proviruses in the engrafted cells from the asymptomatic carriers in NOD/SCID/gammacnull mice2010
- Author(s)
  Yamamoto I, Takajo I, Umeki K, Morishita K, Hatakeyama K, Kataoka H, Nomura H, Okayama A
- Journal Title
  
  Intervirology
  
  Volume: 53 Pages: 229-39
- DOI
  10.1159/000302760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] SKI and MEL1 cooperate to inhibit transforming growth factor-βsignal in gastric cancer cells2009
- Author(s)
  Takahata M, Inoue Y, Tsuda H, Imoto I, Koinuma D, Hayashi M, Ichikura T, Yamori T, Nagasaki K, Yoshida M, Matsuoka, K, Morishita K, Yuki K., Hanyu A, Miyazawa K, Inazawa J, Miyazono K, Imamura T
- Journal Title
  
  J Biol. Chem
  
  Volume: 285 Pages: 3334-3344
- DOI
  10.1074/jbc.m808989200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] Alteration of enhancer of polycomb 1 at 10p11. 2 is one of the genetic events leading to development of adult T-cell leukemia/lymphoma2009
- Author(s)
  Nakahata, S., Saito, Y., Hamasaki, M., Hidaka, T., Arai, Y., Taki, T., Taniwaki, M., Morishita, K
- Journal Title
  
  Genes, Chromosomes & Cancer
  
  Volume: 48 Pages: 768-776
- DOI
  10.1002/gcc.20681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098
[Journal Article] TSLC1 is a novel and useful surface marker for adult T-cell leukemia2007
- Author(s)
  Kazuhiro, Morishita, et. al.
- Journal Title
  
  HTLV-1 and the disease
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Journal Article] Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression2005
- Author(s)
  Hiromi Yuasa, Yuichi Oike, Atsushi Iwama, Ichiro Nishikata, Daisuke Sugiyama, Archibald Perkins, Michael L Mucenski, Toshio Suda, Kazuhiro Morishita
- Journal Title
  
  The EMBO Journal VOL 24-NO 11
  
  Pages: 1967-1987
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590950
[Patent] 細胞接着阻害剤、細胞増殖阻害剤、並びに癌の検査方法および検査用キット2012
- Inventor(s)
  森下和広　斎藤祐介
- Industrial Property Rights Holder
  森下和広　斎藤祐介
- Industrial Property Rights Type
  特許
- Filing Date
  2012-05-11
- Overseas
- Data Source
  KAKENHI-PUBLICLY-23118523
[Patent] 細胞接着阻害剤、細胞増殖阻害剤、並びに癌の検査方法および検査用キット2011
- Inventor(s)
  森下和広、齋藤祐介
- Industrial Property Rights Holder
  宮崎大学
- Filing Date
  2011-11-09
- Data Source
  KAKENHI-PUBLICLY-23118523
[Patent] ヒトT細胞白血病ウイルス感染あるいは成人T細胞白血病発症の検出法、その診断薬、ならびにその予防および治療の為の薬剤2011
- Inventor(s)
  森下和広,谷脇雅史、濱崎誠
- Industrial Property Rights Holder
  宮崎大学、宮崎県産業支援財団
- Acquisition Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21390098
[Patent] 細胞接着阻害剤、細胞増殖阻害剤、並びに癌の検査方法および検査用キット2011
- Inventor(s)
  森下和広
- Industrial Property Rights Holder
  宮崎大学
- Filing Date
  2011-11-09
- Data Source
  KAKENHI-PROJECT-21390098
[Patent] Tリンパ性白血病の検出方法及び検出用キット2011
- Inventor(s)
  森下和広、坪内博仁、谷脇雅史
- Industrial Property Rights Holder
  JST、宮崎大学
- Acquisition Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-21390098
[Patent] PTENのリン酸化抑制剤又は脱リン酸化剤2010
- Inventor(s)
  森下和広、中畑新吾、濱崎誠
- Industrial Property Rights Holder
  宮崎大学、宮崎県産業支援財団
- Filing Date
  2010-03-26
- Overseas
- Data Source
  KAKENHI-PROJECT-21390098
[Patent] 成人T細胞白血病の診断器具2010
- Inventor(s)
  森下和広,小林行治
- Industrial Property Rights Holder
  みやざきTLO→宮崎県産業支援財団、アドテック
- Acquisition Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21390098
[Patent] 細胞接着阻害剤およびその用途2009
- Inventor(s)
  山川哲生, 森下和広
- Industrial Property Rights Holder
  宮崎大学TLO
- Industrial Property Number
  2009-041204
- Filing Date
  2009-02-24
- Data Source
  KAKENHI-PROJECT-20012043
[Patent] 細胞接着阻害剤およびその用途2009
- Inventor(s)
  森下和広、山川哲生
- Industrial Property Rights Holder
  宮崎大学
- Industrial Property Number
  2009-041204
- Filing Date
  2009-02-04
- Data Source
  KAKENHI-PROJECT-21659241
[Patent] 細胞接着阻害剤およびその用途2009
- Inventor(s)
  森下和広、山川哲生
- Industrial Property Rights Holder
  宮崎大学
- Industrial Property Number
  2009-041204
- Filing Date
  2009-02-04
- Data Source
  KAKENHI-PROJECT-20012043
[Patent] 抗IgSF4抗体及びその利用2006
- Inventor(s)
  黒澤良和その他, (森下和広含む)
- Industrial Property Rights Holder
  黒澤良和その他, (森下和広含む)
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-18590302
[Patent] 抗IgSF4抗体及びその利用2005
- Inventor(s)
  黒沢良和、鵜飼由範、森下和広, 他
- Industrial Property Rights Holder
  抗体研究所
- Industrial Property Number
  2005-054624
- Filing Date
  2005-02-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] Cell adhesion molecule 1 (CADM1) is an attractive target for the diagnosis and treatment of adult T-cell leukemia/lymphoma.2019
- Author(s)
  Tomonaga Ichikawa, Ayako Nakatake, Bidhan Sarker, Shingo Nakahata, Kuniyo Sakamoto, Shunsuke Shimosaki, Ichiro Nishikata, Toshiyuki Shiraga, Kazuhiro Morishita
- Organizer
  19th INTERNATIONAL CONFERENCE ON HUMAN RETROVIROLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] 1.Toward the practical application of novel diagnostic tests and development of early detection markers for Adult T-Cell Leaukemia/Lymphoma in HTLV-1-carriers by host-parasite interaction in Peru.2019
- Author(s)
  Shingo Nakahata, Eiji Nagayasu, Kazuhiro Morishita, Hruhiko Maruyama, Yutaka Suzuki, Masao Iwanaga, Yuetsu Tanaka, Martin Montes, Eduardo Gotuzzo.
- Organizer
  19th International Conference On Human Retrovirology
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Analysis of the molecular mechanism of metabolism and tumorigenesis through the loss of tumor suppressor gene NDRG22019
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Kazuhiro Morishita.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] PRMT5 inhibition is synthetic lethal with loss of NDRG2 through the suppression of HSP90A in ATL2019
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Masaya Ono, Hidekatsu Iha, and Kazuhiro Morishita.
- Organizer
  第81回日本血液学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Anti-transferrin receptor1(TFR1)antibody is a promising drug candidate for the treatment of adult T-cell leukemia/lymphoma2019
- Author(s)
  Shingo Nakahata, Shunsuke Shimosaki, Tomonaga Ichikawa, Takuro Kameda, Tomonori Hidaka, Yoko Kubuki, Gene Kurosawa, Kazuya Shimoda, Kazuhiro Morishita
- Organizer
  19th INTERNATIONAL CONFERENCE ON HUMAN RETROVIROLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] ATLにおけるCADM1発現の機能とその臨床的意義2019
- Author(s)
  中畑新吾、Chilmi Syahrul、Yanuar Fauzi、市川朝永、森下和広
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] 2.ペルーにおける糞線虫重複感染によるATLL発症機構解明とその発症予防・治療法の開発を目指して2019
- Author(s)
  森下和広、中畑新吾、長安英治、丸山治彦、鈴木穣、岩永正子、田中勇悦、Martin Montes、Eduardo Gotuzzo
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] The inhibition of EZH2 suppresses ATL development through the up-regulation of novel tumor suppressor gene2019
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, Kazuhiro Morishita.
- Organizer
  第92回日本生化学会.
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Down-regulation of p47 induces high expression of CADM1 via the NF-κB pathway in adult T-cell leukemia/lymphoma2019
- Author(s)
  中畑新吾、Bidhan Sarkar、西片一郎、市川朝永、藤井雅寛、伊波英克、森下和広
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Development of a therapeutic antibody targeting CADM1 for the treatment of ATLL2019
- Author(s)
  Syahrul Chilmi、中畑新吾、市川朝永、松浦正、黒澤仁、森下和広
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Toward the practical application of novel diagnostic tests and development of early detection markers for Adult T-Cell Leaukemia/Lymphoma in HTLV-1-carriers by host-parasite interaction in peru2019
- Author(s)
  Shingo Nakahata, Eiji Nagayasu, Kazuhiro Morishita, Hruhiko Maruyama, Yutaka Suzuki, Masao Iwanaga, Yuetsu Tanaka, Martin Montes, Eduardo Gotuzzo
- Organizer
  19th INTERNATIONAL CONFERENCE ON HUMAN RETROVIROLOGY
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] ATLにおけるCADM1発現の機能とその臨床的意義2019
- Author(s)
  中畑新吾、Chilmi Syahrul、Yanuar Fauzi、市川朝永、森下和広
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] ATLLにおける可溶性CADM1の産生機序2019
- Author(s)
  吉浜麻生、中畑新吾、市川朝永、森下和広
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Development of a therapeutic antibody targeting CADM1 for the treatment of ATLL2019
- Author(s)
  Syahrul Chilmi、中畑新吾、市川朝永、松浦正、黒澤仁、森下和広
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Toward the practical application of novel diagnostic tests and development of early detection markers for Adult T-Cell Leaukemia/Lymphoma in HTLV-1-carriers by host-parasite interaction in peru2019
- Author(s)
  Shingo Nakahata, Eiji Nagayasu, Kazuhiro Morishita, Hruhiko Maruyama, Yutaka Suzuki, Masao Iwanaga, Yuetsu Tanaka, Martin Montes, Eduardo Gotuzzo
- Organizer
  19th INTERNATIONAL CONFERENCE ON HUMAN RETROVIROLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] ATLLにおける可溶性CADM1の産生機序2019
- Author(s)
  吉浜麻生、中畑新吾、市川朝永、森下和広
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] がん抑制遺伝子NDRG2発現低下によるJak/STAT情報伝達系活性化機構2019
- Author(s)
  市川朝永、中畑新吾、尾野雅哉、中武彩子、阪本訓代、森下和広
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] ATLにおける可溶型CADM1の産生亢進機構2019
- Author(s)
  吉浜麻生, 中畑新吾, 市川朝永, 森下和広
- Organizer
  第78回日本癌学会.
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Cell adhesion molecule 1 (CADM1) is an attractive target for the diagnosis and treatment of adult T-cell leukemia/lymphoma.2019
- Author(s)
  Tomonaga Ichikawa, Ayako Nakatake, Bidhan Sarker, Shingo Nakahata, Kuniyo Sakamoto, Shunsuke Shimosaki, Ichiro Nishikata, Toshiyuki Shiraga, Kazuhiro Morishita
- Organizer
  19th INTERNATIONAL CONFERENCE ON HUMAN RETROVIROLOGY
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] EZH2 overexpression in ATL promotes epigenetic silencing of tumor suppressor gene NDRG2.2019
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, and Kazuhiro Morishita.
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] 新規がん抑制遺伝子ＮＤＲＧ2欠損マウスにおける脂質代謝異常および腫瘍形成機能の解析2018
- Author(s)
  市川朝永、中畑新吾、山口良二、二口充、森下和広
- Organizer
  先端モデル動物支援プラットフォーム
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] トランスフェリン受容体抗体はモガムリズマブ治療難治性のATLLの増殖抑制に有効である.2018
- Author(s)
  中畑新吾、下崎俊介、市川朝永、亀田拓郎、日高智徳、久冨木庸子、黒澤仁、下田和哉、森下和広.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Identification of novel antisense RNAs in the genome of bovine leukemia virus (BLV).2018
- Author(s)
  Shingo Nakahata, Chikako Tani, Tomonaga Ichikawa, Hirohisa Mekata, Kazuhiro Morishita
- Organizer
  第30回世界牛病学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Identification of novel antisense RNAs in the genome of bovine leukemia virus (BLV).2018
- Author(s)
  Shingo Nakahata, Chikako Tani, Tomonaga Ichikawa, Hirohisa Mekata, Kazuhiro Morishita.
- Organizer
  第30回世界牛病学会2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] EZH2 overexpression in ATL promotes epigenetic silencing of tumor suppressor gene NDRG2.2018
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, and Kazuhiro Morishita.
- Organizer
  The 9th JSH International Symposium
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] アルギニンメチル化転移酵素PRMT5異常活性によるATL発症機構の解析.2018
- Author(s)
  市川朝永、Obeid Shanab、中畑新吾、尾野雅哉、伊波英克、中武彩子、阪本訓代、森下和広
- Organizer
  第5回日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] 成人T細胞白血病/リンパ腫（ATLL）の発症機構2018
- Author(s)
  森下和広
- Organizer
  日本人類遺伝学会主催　第25回臨床採苗遺伝学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] HTLV-1 infection in Peru and Japan2018
- Author(s)
  森下和広、中畑新吾、長安英治、丸山治彦、鈴木穣、岩永正子、田中勇悦、Martin Montes、Eduardo Gotuzzo
- Organizer
  第18回日秘国際医学シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] ATLにおけるオートファジーによるNF-κB負の制御因子p47の不活化は、NF-κBシグナルを増強しCADM1高発現をもたらす.2018
- Author(s)
  中畑新吾、Bidhan Sarkar、西片一郎、市川朝永、藤井雅寛、井上純一郎、伊波英克、下田和哉、森下和広.
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] High efficacy of anti-TFR1 antibody against the growth of mogamulizmab-resistant ATLL cells2018
- Author(s)
  Shingo Nakahata, Shunsuke Shimosaki, Tomonaga Ichikawa, Takuro Kameda, Tomonori Hidaka, Yoko Kubuki, Gene Kurosawa, Kazuya Shimoda, Kazuhiro Morishita.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Short-form of BCL11B contributes to tumorigenesis of adult T-cell leukemia/lymphoma.2018
- Author(s)
  Happy Kurnia Permatasari, Shingo Nakahata, Tomonaga Ichikawa, Kotaro Shide, Takuro Kameda, Kazuya Shimoda, Masaya Ono, Kazuhiro Morishita.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] 成人T細胞白血病/リンパ腫（ATLL）の発症機構2018
- Author(s)
  森下和広
- Organizer
  日本人類遺伝学会主催　第25回臨床採苗遺伝学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] アルギニンメチル化転移酵素PRMT5異常活性によるATL発症機構の解析.2018
- Author(s)
  市川朝永、Obeid Shanab、中畑新吾、尾野雅哉、伊波英克、中武彩子、阪本訓代、森下和広
- Organizer
  第5回日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] EZH2 overexpression in ATL promotes epigenetic silencing of tumor suppressor gene NDRG22018
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, and Kazuhiro Morishita.
- Organizer
  The 9th JSH International Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Overexpression of EZH2 confers ATL development through the suppression of tumor suppressor gene NDRG2.2018
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, Kazuhiro Morishita.
- Organizer
  第80回日本血液学会.
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] ATLにおけるオートファジーによるNF-κB負の制御因子p47の不活化は、NF-κBシグナルを増強しCADM1高発現をもたらす.2018
- Author(s)
  中畑新吾、Bidhan Sarkar、西片一郎、市川朝永、藤井雅寛、井上純一郎、伊波英克、下田和哉、森下和広.
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Overexpression of EZH2 confers ATL development through the suppression of tumor suppressor gene NDRG2.2018
- Author(s)
  Tomonaga Ichikawa, Shingo Nakahata, Kazuhiro Morishita.
- Organizer
  第80回日本血液学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] HTLV-1 infection in Peru and Japan2018
- Author(s)
  Kazuhiro Morishita
- Organizer
  第18回日秘国際医学シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Maintenance of HSP90A by PRMT5 arginine methylation by NDRG2-deficient ATLL and other cancers2018
- Author(s)
  Kazuhiro Morishita1 , Tomonaga Ichikawa1 , Shingo Nakahata1 , Masaya Ono
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] High efficacy of anti-TFR1 antibody against the growth of mogamulizmab-resistant ATLL cells.2018
- Author(s)
  Shingo Nakahata, Shunsuke Shimosaki, Tomonaga Ichikawa, Takuro Kameda, Tomonori Hidaka, Yoko Kubuki, Gene Kurosawa, Kazuya Shimoda, Kazuhiro Morishita.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Identification of novel antisense RNAs in the genome of bovine leukemia virus (BLV)2018
- Author(s)
  Shingo Nakahata, Chikako Tani, Tomonaga Ichikawa, Hirohisa Mekata, Kazuhiro Morishita
- Organizer
  第30回世界牛病学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07203
[Presentation] Short-form of BCL11B contributes to tumorigenesis of adult T-cell leukemia/lymphoma.2018
- Author(s)
  Happy Kurnia Permatasari, Shingo Nakahata, Tomonaga Ichikawa, Kotaro Shide, Takuro Kameda, Kazuya Shimoda, Masaya Ono, Kazuhiro Morishita.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Arginine methylation of HSP90A by protein arginine methyltransferase PRMT5 promotes development of adult T-cell leukemia.2018
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Masaya Ono, Hidekatsu Iha, and Kazuhiro Morishita
- Organizer
  第77回日本癌学会.
- Data Source
  KAKENHI-PROJECT-17H04600
[Presentation] Arginine methylation of HSP90A by protein arginine methyltransferase PRMT5 promotes development of adult T-cell leukemia.2018
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Masaya Ono, Hidekatsu Iha, and Kazuhiro Morishita.
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] トランスフェリン受容体抗体はモガムリズマブ治療難治性のATLLの増殖抑制に有効である.2018
- Author(s)
  中畑新吾、下崎俊介、市川朝永、亀田拓郎、日高智徳、久冨木庸子、黒澤仁、下田和哉、森下和広.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Short-from of BCL11B contributes to tumorigenesis of adult T-cell leukemia2017
- Author(s)
  Happy Permatasari,　中畑新吾,　市川朝永,　齋藤祐介,　滝智彦,　谷脇雅史,　森下和広
- Organizer
  平成29年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Down-regulation of p47 induces high expression of CADM1 via the NF-kB pathway in adult T-cell leukemia2017
- Author(s)
  Bidhan Sarkar,　西片一朗,　中畑新吾,　市川朝永,　藤井雅寛,　伊波英克,　森下和広
- Organizer
  平成29年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] アルギニンメチル化によるHSP90A活性調節機構の解析2017
- Author(s)
  市川朝永,　Obeid Shanab,　中畑新吾,　伊波英克,　尾野雅哉,　中武彩子,　阪本訓代,　森下和広
- Organizer
  平成29年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] 新規がん抑制遺伝子NDRG2によるがん進展および転移の分子機構の解明2017
- Author(s)
  市川朝永、田村知丈、中畑新吾、二口充、森下和広.
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] 成人T細胞白血病(ATL)に対するアルギニンメチル化転移酵素PRMT5阻害による抗腫瘍効果の検討2017
- Author(s)
  市川朝永、Obeid Shanab、中畑新吾、伊波英克、尾野雅哉、中武彩子、阪本訓代、森下和広
- Organizer
  第4回日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Synthetic lethality of PRMT5 inhibition in NDRG2-deficient adult T-cell leukemia through HSP90A dysfunction2017
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Shunsuke Shimosaki, Nawin Manachai, Hidekatsu Iha, Kazuya Shimoda, Masaya Ono, Mohammed N. Ismail, Ahmed Y. Nassar and Kazuhiro Morishita. 
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] ATLにおけるNDRG2発現低下は細胞ストレス応答異常に関与する2017
- Author(s)
  中畑新吾、市川朝永、斎藤祐介、滝智彦、谷脇雅史、森下和広
- Organizer
  第4回日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Superoxide-generating Nox5alpa contributes to malignancy of human T-cell leukemia virus type 1-transformed cells through redox regulation2016
- Author(s)
  Tomonari Shigemura, Masaaki Shiohara, Masayoshi Kato, Kazuko Kaneda, Kazuhiro Morishita, Hiroo Hasegawa, Masahiro Fujii, Agnes Gorlach, Kenichi Koike, Tohru Kamata
- Organizer
  Cold Spring Harbor Asia Conferences, Cancer Metabolism
- Place of Presentation
  World Hotel Grand Dushulake Suzhou,　蘇州市(中国)
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08628
[Presentation] HTLV-1感染によるがん抑制遺伝子NDRG2発現調節機構の解析2015
- Author(s)
  市川朝永、中畑新吾、中武彩子、森永樹、森下和広
- Organizer
  第二回HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 成人T細胞白血病に対する抗トランスフェリン受容体抗体治療薬の開発2015
- Author(s)
  下崎俊介、黒澤仁、張黎臨、須藤幸夫、黒澤和良、中畑新吾、市川朝永、森下和広
- Organizer
  第二回HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂 (東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] Proteosomal degradation of p47 by HTLV-1 Tax and p47 promoter methylation enhanced CADM1 expression in ATLL cells2015
- Author(s)
  Ichiro Nishikawa, Shingo Nakahata, Tomonaga Ichikawa, Masahiro Fujii, Hidekatsu Iha, Yuetsu Tanaka, Kazuhiro Morishita
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] ATL細胞におけるCADM1高発現はP47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015
- Author(s)
  森下和広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] Dysregulation of hypoxia response by NDRG2 down-regulation in ATL2015
- Author(s)
  中畑新吾、市川朝永、斎藤祐介、滝智彦、谷脇雅史、森下和広
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] CADM1/TSLC1発現は進行性セザリー症候群の生物学的マーカーである2015
- Author(s)
  岩月啓氏、岩田浩明、藤井一恭、森下和広、大島孝一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市)
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] 成人T細胞白血病に対する抗hTfR抗体を用いた医薬品の開発に関する研究2015
- Author(s)
  下崎俊介、中畑新吾、市川朝永、森下和広、黒澤仁、黒澤良和、張黎臨、須藤幸夫
- Organizer
  第22回技術・研究発表交流会
- Place of Presentation
  宮崎市民プラザ (宮崎県宮崎市）
- Year and Date
  2015-09-30
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] PIポリアミドを用いたEVI1依存的GPR56転写制御2015
- Author(s)
  兼田（中島）加珠子、下崎俊介、末金彰、斎藤祐介、渡部隆義、長瀬浩喜　森下和広
- Organizer
  第77回日本血液学会、
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2発現低下がAKT情報伝達系の亢進を介して抗うつ状態を改善する2015
- Author(s)
  市川朝永、中畑新吾、田村知丈、Nawin　Manachai、森下和広
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ATL細胞におけるCADM1高発現はP47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015
- Author(s)
  森下和広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] Down-regulation of NDRG2 plays an important role in ATLL leukemogenesis via the PTEN-mediated PI3K/AKT signaling pathway.2015
- Author(s)
  Shingo Nakahata, Tomonaga Ichikawa, Yusuke Saito, Yasuhito Arai, Tomohiko Taki, Masafumi Taniwaki, Kazuhiro Morishita
- Organizer
  44th Annual Scientific Meeting of The Society for Hematology and Stem Cells (ISEH 2015)
- Place of Presentation
  国立京都国際会館（京都府左京区）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2発現低下がPTENおよびNIKリン酸化によってNF-κB活性が促進されATLLを発症する2015
- Author(s)
  市川朝永、中畑新吾、藤井雅寛、伊波英克、森下和広
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] HTLV-1感染によるがん抑制遺伝子NDRG2発現調節機構の解析2015
- Author(s)
  市川朝永、中畑新吾、中武彩子、森永樹、森下和広
- Organizer
  第二回HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂 (東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] ATLにおけるNDRG2発現低下による低酸素応答の異常調節2015
- Author(s)
  中畑新吾、市川朝永、齋藤祐介、滝智彦、谷脇雅史、森下和広
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2はPI3Kシグナル伝達系の負のフィードバック因子として働く―低酸素ストレス抵抗性への関与2015
- Author(s)
  中畑新吾、市川朝永、齋藤祐介、森下和広
- Organizer
  第二回HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2はPI3Kシグナル伝達系の負のフィードバック因子として働く―低酸素ストレス抵抗性への関与2015
- Author(s)
  中畑新吾、市川朝永、齋藤祐介、森下和広
- Organizer
  第二回HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂 (東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] Proteosomal degradation of p47 by HTLV-1 Tax and p47 promoter methylation enhanced CADM1 expression in ATLL cells2015
- Author(s)
  Ichiro Nishikawa, Shingo Nakahata, Tomonaga Ichikawa, Masahiro Fujii, Hidekatsu Iha, Yuetsu Tanaka, Kazuhiro Morishita
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 成人T細胞白血病に対する抗トランスフェリン受容体抗体治療薬の開発2015
- Author(s)
  下崎俊介、黒澤仁、張黎臨、須藤幸夫、黒澤和良、中畑新吾、市川朝永、森下和広
- Organizer
  第二回HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] Dysregulation of hypoxia response by NDRG2 down-regulation in ATL2015
- Author(s)
  中畑新吾、市川朝永、斎藤祐介、滝智彦、谷脇雅史、森下和広
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ATL細胞におけるCADM1高発現はp47発現阻害に働くHTLV1 Taxとプロモーターメチル化に依存する2015
- Author(s)
  森下数広、西片一朗、中畑新吾、市川朝永、藤井雅寛、伊波英克、田中勇悦
- Organizer
  日本癌学会学術総会
- Place of Presentation
  Nagoya congress center (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461426
[Presentation] Direct growth inhibitory effets of immunomodulatory drug against various blood cell tumors2015
- Author(s)
  Emi Ikebe, Shunsuke Shimozaki, Nihole Fife, Mitsuo Hori, Hiroo Hasegawa, Kazuhiro Morishita,
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会・合同大会
- Place of Presentation
  神戸神戸ポートアイランド(兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2発現低下がPTENおよびNIKリン酸化によってNF-κB活性が促進されATLLを発症する2015
- Author(s)
  市川朝永、中畑新吾、藤井雅寛、伊波英克、森下和広
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] CADM1/TSLC1発現は進行性セザリー症候群の生物学的マーカーである2015
- Author(s)
  岩月啓氏、岩田浩明、藤井一恭、森下和広、大島孝一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] レナリミドの直接的なATL細胞増殖抑制効果の評価2015
- Author(s)
  池辺詠美、下崎俊介、ファイフ　ニコール、堀光雄、長谷川寛雄、森下和広、伊波英克
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K15087
[Presentation] レナリミドの直接的なATL細胞増殖抑制効果の評価2015
- Author(s)
  池辺詠美、下崎俊介、ファイフ　ニコール、堀光雄、長谷川寛雄、森下和広、伊波
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] EVI1高発現急性骨髄性白血病におけるmonosomy7ゲノム異常の解析2014
- Author(s)
  末金彰、兼田加珠子、ManachaiNawin、森下和広
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] Improvement therapeutic efficacy by neutralizing antibody of integrinA6/B4 for EVI1 high AML2014
- Author(s)
  Kazuko Kaneda-Nakashima, Akira Suekane, Jin Kurosawa, Yuko Sudo, Akiyuki Furuya, Kazuhiro Morishita
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] 前立腺癌患者血漿および細胞株におけるCaveolin-1の発現とその意義に関する検討2014
- Author(s)
  杉江悟、向井尚一郎、月野浩昌、西片一朗、森下和広、賀本敏行
- Organizer
  第23回泌尿器科分子細胞研究会
- Place of Presentation
  山形市
- Data Source
  KAKENHI-PROJECT-24592398
[Presentation] NDRG2はPPA2を介してNIK活性を制御し、恒常的NF-ｋB活性を抑制する2014
- Author(s)
  市川朝永、中畑新吾、藤井雅寛、伊波英克、森下和広
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] PI3Kシグナルによるエンドサイトーシス制御に関与する分子の探索2014
- Author(s)
  中畑新吾、市川朝永、新井康仁、滝智彦、谷脇雅史、森下和広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] 骨軟骨分化におけるMEL1/PRDM16の機能解析2014
- Author(s)
  兼田加珠子、井川加織、太田智美、関本朝久、帖佐悦男、迫田隅男、今泉和則、ﾏﾆｻｲ･ﾌﾟﾃﾞｨ、山口良二、森下和広
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] 骨軟骨分化制御におけるMEL1/PRDM16の機能解析2013
- Author(s)
  兼田（中島）加珠子、井川加織、大田智美、黒木修司、関本朝久、帖佐悦男、迫田隅男、森下和広
- Organizer
  第36回　日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-24592772
[Presentation] Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers2013
- Author(s)
  Nakahata S, Morishita K.:
- Organizer
  16th　International Conference on Human Retrovirolory: HTLV and Related Viruses.
- Place of Presentation
  モントリオール
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] MEL1/PRDM16による骨分化制御機構の解明2013
- Author(s)
  兼田加珠子、井川加織、大田智美、関本朝久、帖佐悦夫、迫田澄男、森下和広
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24592772
[Presentation] MEL1/PRDM16による骨分化制御機構の解明2012
- Author(s)
  兼田加珠子、井川加織、黒木修司、関本朝久、帖佐悦男、迫田隅男、森下和広
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24592772
[Presentation] T細胞特異的TSLC1 TgマウスはATL様病態を示す2011
- Author(s)
  市川朝永、中畑新吾、山口良二、西片一朗、森下和広
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都文京区
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 癌抑制遺伝子NDRG2の炎症反応制御機構2011
- Author(s)
  市川朝永、中畑新吾、近藤雄大、長井健太郎、迫田隅男、森下和広
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] NDRG2は成人T細胞白血病リンパ腫においてがん抑制遺伝子として働く2011
- Author(s)
  中畑新吾、市川朝永、齋藤祐介、新井康仁、滝智彦、谷脇雅史、森下和広
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都文京区
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 腫瘍溶解性ウイルスVSVを用いたATLにたいするTSLC1分子標的療法の開発2011
- Author(s)
  大隈和、舘山誠司、森下和広、広瀬国孝、山本直樹、山口一成、浜口功
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都文京区
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 成人T細胞白血病におけるがん抑制遺伝子候補NDRG2の同定2011
- Author(s)
  中畑新吾、市川朝永、齋藤祐介、新井康仁、滝智彦、谷脇雅史、森下和広
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Clinical significance of CADM1/TSLC1/IgSF4 expression in adult T-cell leukemia/lymphoma Leukemia the 15th International Conference on Human Retrovirology2011
- Author(s)
  Morishita K
- Organizer
  HTLV and Related Retroviruses
- Place of Presentation
  Belgium(Leuven)
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Clinical significance of CADM1/TSLC1/IgSF4 expression in adult T-cell leukemia/lymphoma2011
- Author(s)
  Morishita K.
- Organizer
  The 15th International Conference on Human Retrovirology : HTLV and Related Retroviruses
- Place of Presentation
  Belgium (Leuven)
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] HAM患者PBMCにおけるTSLC-1発現の解析2010
- Author(s)
  竹之内徳博, 恩額日楽, 手塚健太, 森下和広, 鵜飼由範, 黒澤仁, 中川正法, 日下博文, 藤澤順一
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京都港区
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Promoter methylation and down-regulation of ZEB1 are associated with low expression of CDKNIA in ATL-cells2010
- Author(s)
  Nakahata, S., Watanabe, M., Saito, Y., Morishita, K
- Organizer
  69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] ヒトCRTAMを発現する組換えウイルスVSVのHTLV-1感染細胞及びATL細胞に対する殺傷効果2010
- Author(s)
  大隈和, 深川耕次, 高馬卓也, 森下和広, 高浜洋一, 山本直樹, 山口一成, 浜口功
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京都港区
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 可食農水産物由来NF-κB制御化合物(EPNRE)の抗Tax・抗ATL細胞活性2010
- Author(s)
  伊波英克, Mireguli Yasen, 池辺詠美, 石田由布子, 和田浩二, 田中淳一, 田中勇悦, 甲斐久博, 西園晃, 森下和広
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] ATL細胞におけるCDKN1A遺伝子の転写はプロモーターのメチル化とZEB1発現低下により抑制される2010
- Author(s)
  渡邊正明, 中畑新吾, 齋藤祐介, 森下和広
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京都港区
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] CADM1特異抗体を用いたATLL(成人T細胞白血病・リンパ腫)診断・治療法の開発2010
- Author(s)
  眞鍋香澄, 高松尚文, 丸塚浩助, 日高智徳, 中畑新吾, 前田宏一, 齋藤祐介, 濱崎誠, 一ノ瀬孝子, 岩田喬子, 畠山金太, 鵜飼由範, 岡山昭彦, 黒沢仁, 浅田祐士郎, 宇都宮與, 森下和広
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 成人T細胞白血病におけるCDKN1A遺伝子の転写はプロモーターのメチル化とZEB1発現低下により抑制される2010
- Author(s)
  中畑新吾, 渡邊正明, 濱崎誠, 齋藤祐介, 河野洋平, 森下和広
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Promoter methylation and down-regulation of ZEB1 are associated with low expression of CDKN1A in ATL cells2010
- Author(s)
  Nakahata, S., Watanabe, M., Saito, Y., Morishita, K
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 成人T細胞白血病・リンパ腫(ATLL)のTSLC1/IgSF4による診断応用2009
- Author(s)
  眞鍋香澄, 高松尚文, 日高智徳, 中畑新吾, 前田宏一, 濱崎誠, 岩田喬子, 鵜飼由範, 岡山昭彦, 坪内博仁, 黒沢仁, 宇都宮與, 森下和広
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 成人T細胞白血病リンパ腫(ATLL)におけるZEB1/TCF8転写抑制はCCNG2及びCDKN1Aの転写抑制をもたらす2009
- Author(s)
  中畑新吾, 浜崎誠, 渡邊正明, 森下和広
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 血液腫瘍治療の発展2009
- Author(s)
  森下和広
- Organizer
  第13回京都分子血液フォーラム
- Place of Presentation
  ホテルフジタ京都(京都市)
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] CtBP結合型転写因子群による白血病発症機構の解析2009
- Author(s)
  森下和広
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] Down-regulation of CDKN1A transcription by ZEB1/TCF8 inactivation in adult T-cell leukemia2009
- Author(s)
  Nakahata, S., Hamasaki, M., Watanabe, M., and Morishita, K
- Organizer
  68th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Diagnostic application using TSLC1/IgSF4 antibodies to Adult T cell leukemia/lymphoma(ATLL)2009
- Author(s)
  Manabe, K., Takamatsu, N., Hidaka, T., Nakahata, S., Naeda, K., Hamasaki, M., Iwata, T., Ukai, Y., Okayama, A., Horiuchi, H., Kurosawa, G., Utsunomiya, A., and Morishita, K
- Organizer
  68th Annual Meeting of the JapaneseCancer Association
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Human phage antibody libraryを用いた癌細胞表面キャラクターの解析2009
- Author(s)
  黒澤仁, 住友万里子, 村松千徳, 小川恵子, 田中美帆, 北村由香, 杉浦元孝, 高崎昭彦, 林宣宏, 赤堀泰, 高松尚文, 森下和広, 鵜飼由範, 黒澤良和
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] CtBP結合型転写因子群による白血病発症機構2009
- Author(s)
  森下和広
- Organizer
  第11回神奈川血液免疫フォーラム
- Place of Presentation
  小田急ホテルセンチュリー相模大野(相模原市)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] NDRG2 is a candidate tumor suppressor gene in adult-T cell leukemia2009
- Author(s)
  Hamasaki, M., Nakahata, S., Saito, Y., Kawano, Y, Arai, Y, Taki, T., Taniwaki, M., and Morishita, K
- Organizer
  68th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] ITGA6/ITGB4 dependent-cell adhesion ability in EIV1(+) leukemia2009
- Author(s)
  Yamakawa, N., Saito, Y., and Morishita, K
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 染色体ゲノム解析によるATL癌抑制遺伝子の同定2009
- Author(s)
  森下和広
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Evi1による細胞接着機構2009
- Author(s)
  山川哲生, 齋藤祐介, 森下和広
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Identification and characterlization of tumor suppressor genes in ATL by chromosomal and genetic analyses2009
- Author(s)
  Morishita, K., Taniwaki, M., and Nakahata, S
- Organizer
  68th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] CtBP結合型転写因子群による白血病発症機構の解析2009
- Author(s)
  森下和広
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] Comprehensive isolation and characterize of anti-cancer Abs, using the human phage-Abs display system2009
- Author(s)
  Kurosawa, G., Sumitomo, M., Muramatsu, C., Ogawa, K., Hashiba, M., Sugiura, M., Akahori, Y., Manabe, K., Ukai, Y., Morishita, K., and Kurosawa, Y
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] TCF8はSmad7を抑制しATLのTGF-betal不能性を解除する2009
- Author(s)
  中畑新吾, 濱崎誠, 齋藤祐介, 森下和広
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 急性骨髄性白血病の原因遺伝子EVI 1によるGATA-2転写活性化の機能解析2009
- Author(s)
  島原明子, 山川哲生, 齋藤祐介, 西片一朗, 森下和広
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] 口腔扁平上皮癌におけるNDRG2遺伝子の発現とその制御機構の解析2009
- Author(s)
  古田浩史, 近藤雄大, 濱崎誠, 中畑新吾, 迫田隅男, 森下和広
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21390098
[Presentation] EVI1によるGATA転写にはPCAFによるCtBP結合領域のリジンアセチル化が必須である2008
- Author(s)
  島原明子, 山川哲生, 西片一朗, 森下和広
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都市
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] Crucial lysine-acetylation in CtBP binding domain of EVI1 by P/CAF during GATA-2 transcriptional activation2008
- Author(s)
  島原明子, 山川哲生, 西片一朗, 森下和広
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] EVI1によるGATA-2転写活化にはPCAFによるCtBP結合領域のリジンアセチル化が必要である2008
- Author(s)
  島原明子, 山川哲生, 西片一朗, 森下和広
- Organizer
  第31回日分子生物学云云・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20012043
[Presentation] Diagnostics development of adult T-cell Leukemia by a novel surface marker, IGSF4/TSLC12007
- Author(s)
  Morishita, K, et. al.
- Organizer
  2007 Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] Diagnostics development of adult T-cell Leukemia by a novel surface marker,IGSF4/TSLC12007
- Author(s)
  森下和広
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] Diagnostics development of adult T-cell Leukemia by a novel surface marker, IGSF4/TSLC12007
- Author(s)
  森下和広
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] TSLC1 is a novel and useful surface marker for adult T-cell leukemia2006
- Author(s)
  森下和広
- Organizer
  The 55th Fujihara International Seminar
- Place of Presentation
  苫小牧市
- Year and Date
  2006-07-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] Diagnostics development of adult T-cell Leukemia by a novel surface marker IGSF4/TSLC12006
- Author(s)
  Morishita, K, et. al.
- Organizer
  2006 Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] Diagnostics development of adult T-cell Leukemia by a novel surface marker IGSF4/TSLC12006
- Author(s)
  Morishita, K, et. al.
- Organizer
  2006 Annual Meeting of Japanese Society of Hematology(JSH)
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2006-10-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] TSLC1 is a novel and useful surface marker for adult T-cell leukemia2006
- Author(s)
  Morishita, K, et. al.
- Organizer
  The 55th Fujihara International Seminar
- Place of Presentation
  Tomakomai, Japan
- Year and Date
  2006-07-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] 成人T細胞白血病(ATL)に対するTSLC1特異的抗体を用いた臨床応用2006
- Author(s)
  森下和広
- Organizer
  第68回日本血液学会・第48回日本臨床血液学会合同総会
- Place of Presentation
  福岡市
- Year and Date
  2006-10-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] 成人T細胞白血病(ATL)に対するTSLC1特異的抗体を用いた臨床応用2006
- Author(s)
  森下和広
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590302
[Presentation] がん抑制遺伝子NDRG2によるHTLV-1/Tax誘導性NFκB活性抑制機構の解析
- Author(s)
  市川朝永、中畑新吾、森下和広
- Organizer
  第34回日本炎症・再生医学会.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] がん抑制遺伝子NDRG2欠損マウスによる4-NQO誘導性口腔がん発症機構の解析
- Author(s)
  田村知丈、市川朝永、中畑新吾、近藤雄大、馬場貴、長井健太郎、山下善弘、森下和広
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ntegrin A6 as a special marker of refractory leukemia is important for maintaining of leukemia stem cells.
- Author(s)
  Kaneda K, Morishita K.:
- Organizer
  The 11th Stem Cell Research Symposium.
- Place of Presentation
  文京区.
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] New therapeutic approach using anti-human ITGA6/B4 neutralizing antibody for EVI1 high AML
- Author(s)
  Kazuko Kneda, Suekane Akira, Gene Kurosawa, Yukio Sudo, Akiyuki Furuya, Kazuhiro Morishita（
- Organizer
  TENTH　INTERNATIONAL WORKSHOP
- Place of Presentation
  Cincinnati Childrend’s　Hospital Medical Center
- Year and Date
  2014-05-04 – 2014-05-07
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] がん抑制遺伝子NDRG2欠損マウスによる4-NQO誘導性口腔がん発症機構の解析.
- Author(s)
  市川朝永、田村知丈、中畑新吾、迫田隅男、森下和広
- Organizer
  第86回日本生化学会大会.
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2はPP2Aリクルーターとして PTEN及びNIK活性調節に関わる.
- Author(s)
  市川朝永、中畑新吾、藤井雅寛、伊波英克、森下和広
- Organizer
  HTLV-1研究会・シンポジウム
- Place of Presentation
  港区　東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 新規がん抑制遺伝子Ndrg2欠損ﾏｳｽはAKT活性の亢進を介して抗うつ状態を改善する
- Author(s)
  市川朝永、中畑新吾、森下和広
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-16 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ATLやその他のがんにおけるNDRG2発現低下はPTENリン酸化異常をきたし、PI3K/AKT経路を活性化させる
- Author(s)
  中畑新吾、市川朝永、齋藤祐介、滝智彦、谷脇雅史、森下和広
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] MEL/1PRDM16による骨分化制御機構の解明.
- Author(s)
  兼田(中島)加珠子、井川香織、太田智美、岡本朝久、帖佐悦男、迫田隅男、森下和広
- Organizer
  第86回日本生化学会大会.
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2 S332 phosphorylation is necessary to recruit PP2A to dephosphorylate PTEN in a feedback loop in the PI3K pathway
- Author(s)
  Shingo Nakahata1, Tomonaga Ichikawa1, Yasuhito Arai2, Tomohiko Taki3, Masafumi Taniwaki3,4, Kazuhiro Morishita1
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] GPR56は白血病幹細胞の新規治療標的である。
- Author(s)
  兼田(中島)加珠子、末金彰、斎藤祐介、森下和広
- Organizer
  第36回日本分子生物学会年会.
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] Survival and drug resistance of LSCs Cell by integrin alpha 6 in EVI1high AML.
- Author(s)
  Kaneda K, Suekane A, Yamakawa N, Saito Y, Morishita K
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] 血中可溶型CADM1/TSLC1測定によるATL診断法の開発.
- Author(s)
  中武彩子、小林行治、西片一朗、中畑新吾、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡榮三朗、瀬戸口充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
- Organizer
  HTLV-1研究会・シンポジウム
- Place of Presentation
  港区　東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ATL細胞におけるCADM1高発現はHTLV-1 Taxを含むNF-κB活性化に依存する.
- Author(s)
  西片一朗、市川朝永、中畑新吾、藤井雅寛、伊波英克、白神俊幸、田中勇悦、森下和広
- Organizer
  ６回HTLV-1研究会・シンポジウム.
- Place of Presentation
  港区　東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 細胞外排出低分子量メタボライトの定量によるATL細胞のプロファイリング
- Author(s)
  伊波英克、池辺詠美、越海ニコール、緒方正男、手塚健太、松本昴、末岡栄三郎、堀光雄、長谷川寛雄、森下和広、田中勇悦、藤沢順一、紙健次郎、
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] ATLやその他のがんにおけるNDRG2発現低下はPTENリン酸化異常をきたし、PI3K/AKT経路を活性化させる　（第76回日本血液学会学術集会　　2014.11.1　大阪）ポスター
- Author(s)
  兼田加珠子、井川加織、太田智美、関本朝久、帖佐悦男、迫田隅男、今泉和則、ﾏﾆｻｲ･ﾌﾟﾃﾞｨ、山口良二、森下和広
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-16 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] PTENリン酸化異常に伴う白血病、癌発症機構
- Author(s)
  森下和広、中畑新吾、市川朝永
- Organizer
  第87回日本生化学会大会　京都
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-16 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] NDRG2はPP2Aリクルーターとして PTEN及びNIK活性調節に関わる
- Author(s)
  市川朝永、中畑新吾、藤井雅寛、伊波英克、森下和広
- Organizer
  ６回HTLV-1研究会・シンポジウム.
- Place of Presentation
  港区
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] Integrin A6 as a special marker of refractory leukemia is important for maintaining of leukemia stem cells.
- Author(s)
  Kaneda K, Morishita K.
- Organizer
  The 11th Stem Cell Research Symposium.
- Place of Presentation
  文京区　東京大学
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] Improvement therapeutic efficacy by neutralizing antibody of integrinA6/B4 for EVI1 high AML （
- Author(s)
  Kazuko Kaneda-Nakashima, Akira Suekane, Jin Kurosawa, Yuko Sudo, Akiyuki Furuya, Kazuhiro Morishita
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] がん抑制遺伝子NDRG2によるHTLV-1/Tax誘導性NFκB活性抑制機構の解析.
- Author(s)
  市川朝永、中畑新吾、森下和広
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] PI3Kシグナルによるエンドサイトーシス制御に関与する分子の探索
- Author(s)
  中畑新吾、市川朝永、新井康仁、滝智彦、谷脇雅史、森下和広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] 骨軟骨分化制御におけるMEL1/PRDM16の機能解析
- Author(s)
  兼田(中島)加珠子、井川加織、太田智美、黒木修司、関本朝久、帖佐悦男、迫田隅男、森下和広
- Organizer
  第36回日本分子生物学会年会.
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] NDRG2はPPA2と共にHTLV-1感染による活性化PI3K/AKTとNF-ｋB情報伝達を阻害する
- Author(s)
  森下和広、中畑新吾、市川朝永
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] nvestigation of therapeutic efficacy of neutralizing antibody of integrin for AML.
- Author(s)
  Kaneda K, Suekane A, Saito Y, Yamakawa N, Kurosawa J, Morishita K
- Organizer
  72th Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] New therapeutic approach using anti-human ITGA6/B4 neutralizing antibody for EVI1 high AML
- Author(s)
  Kazuko Kneda, Suekane Akira, Gene Kurosawa, Yukio Sudo, Akiyuki Furuya, Kazuhiro Morishita（
- Organizer
  TENTH　INTERNATIONAL WORKSHOP
- Place of Presentation
  Cincinnati Childrend’s　Hospital Medical Center
- Year and Date
  2014-05-04 – 2014-05-07
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] ATLにおける新規PTENキナーゼの同定と機能解析（
- Author(s)
  市川朝永、中畑新吾、森下和広
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2014-08-23 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25293081
[Presentation] Investigation of MEL1/PRDM16 function in bone differentiation.
- Author(s)
  Kaneda-Nakashima K, Igawa K, Ohta T, Sekimoto T, Chosa E, Imaizumi K, Phudit M, Yamaguchi R, Sakoda S, Morishita K.
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24592772
[Presentation] 血中可溶型CADM1/TSLC1測定によるATL診断法の開発.
- Author(s)
  中武彩子、小林行治、西片一朗、中畑新吾、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡榮三朗、瀬戸口充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
- Organizer
  第６回HTLV-1研究会・シンポジウム.
- Place of Presentation
  港区
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] MEL/1PRDM16による骨分化制御機構の解明.
- Author(s)
  兼田(中島)加珠子、井川香織、太田智美、岡本朝久、帖佐悦男、迫田隅男、森下和広：
- Organizer
  第86回日本生化学会大会.
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PUBLICLY-25118720
[Presentation] 血中可溶性CADM1/TSLC1測定によるATL診断法の開発
- Author(s)
  中武彩子、小林行治、中畑新吾、西片一朗、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡栄三朗、瀬戸山充、岡山昭彦、宇都宮與、下田和哉、渡邊俊樹、森下和広
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2014-08-23 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25293081

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# of Collaborated Projects: 10 results

# of Collaborated Products: 121 results
2. NISHIKATA Ichiro (50253844)

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# of Collaborated Products: 13 results
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23. MORISHITA Shinichi (90292854)

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# of Collaborated Projects: 1 results

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29. TAKESHIMA Hideo (70244134)

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30. ASANO Shigetaka (50134614)

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# of Collaborated Projects: 1 results

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57. FUJII Kazuyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. OKUMA Kazu

# of Collaborated Projects: 0 results

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59. Hara Toshifumi

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# of Collaborated Products: 1 results
60. OHTA Hiroshi

# of Collaborated Projects: 0 results

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# of Collaborated Products: 1 results
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# of Collaborated Products: 1 results
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83. 永瀬浩喜

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84. 岡山昭彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
85. 下田和哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
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# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
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88. 江藤望

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# of Collaborated Products: 1 results

MORISHITA Kazuhiro 森下 和広

森下 和廣 モリシタ カズヒロ

森下 和弘 モリシタ カズヒロ

森下 和広 モリシタ カズヒロ

森下 和宏 モリシタ カズヒロ

Research Projects

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Mechanism of Adult T-Cell Leukemia Development Dependent on Metabolic Aberration Caused by NDRG2 DeficiencyPrincipal Investigator

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Dysregulation of stress signaling leading to oncogenesis by NDRG2-deficicencyPrincipal Investigator

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Comparative genomic analysis of high frequent ATL development due to HTLV-1 superinfection in PeruPrincipal Investigator

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Analysis of ATL development dependent on abnormalities of intestinal floraPrincipal Investigator

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EVI1・MEL1ファミリーによる細胞運命決定能Principal Investigator

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Analysis of ATL leukemogenesis through breakage of defense mechanism of HTLV-1 infectionPrincipal Investigator

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MORISHITA Kazuhiro 森下和広

森下和廣モリシタカズヒロ

森下和弘モリシタカズヒロ

森下和広モリシタカズヒロ

森下和宏モリシタカズヒロ