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Takagi Masatoshi  高木 正稔

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TAKAGI Masatoshi  高木 正稔

高木 正稔  タカギ マサトシ

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Researcher Number 10406267
Other IDs
Affiliation (Current) 2026: 東京科学大学, 大学院医歯学総合研究科, 教授
Affiliation (based on the past Project Information) *help 2026: 東京科学大学, 大学院医歯学総合研究科, 教授
2024: 東京科学大学, 大学院医歯学総合研究科, 教授
2022 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座教授
2018 – 2021: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授
2017: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座准教授 … More
2016: 東京医科歯科大学, 茨城県小児・周産期地域医療学講座, 准教授
2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授
2015: 東京医科歯科大学, 医学部, 講師
2011 – 2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 講師
2010 – 2013: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師
2012: 東京医科歯科大学, 大学院・, 講師
2011: 東京医科歯科大学, 医歯学総合研究科, 講師
2010: 東京医科歯科大学, 講師
2010: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師(昇任)
2009: 東京医科歯科大学, 医歯学総合研究科, 助教
2008: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教
2006: 国際医療福祉大学, 保健学部, 講師 Less
Review Section/Research Field
Principal Investigator
Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Applied pharmacology / Hematology / Embryonic/Neonatal medicine
Keywords
Principal Investigator
ATM / T細胞受容体 / 原発性免疫不全症 / 乳児白血病 / 小児急性リンパ性白血病 / 疾患感受性 / レアバリアント / 急性リンパ性白血病 / B細胞分化 / 遺伝的背景 … More / 小児 / 白血病 / VDJ / 染色体転座 / 毛細血管拡張性運動失調症 / DNA損傷応答機構 / DNA損傷応答 / microRNA / 脂肪細胞分化 / VDJ再構成 / 小児腫瘍学 / 糖尿病 … More
Except Principal Investigator
白血病 / ATM / ゲノムの3次元構造 / 転写 / メチル化 / 免疫不全症 / エピジェネティクス / ThymoD / 非コードRNA / 乳児白血病 / microRNA / 細胞分化 / 急性リンパ性白血病 / 多能性幹細胞 / シングルセルRNA-seq / 臍帯血 / MLL-AF4 / リンパ性白血病 / ゲノムの3次元構造 / 母子保健学 / 長期フォロー / リスク / 母子保健 / 小児悪性腫瘍 / 疫学 / 小児がん / risk / perinatal factor / pregnancy / genetics / leukemia / epidemiology / 中枢神経 / 薬理学 / ゲノム薬理学 / 中枢神経障害 / 白質脳症 / プロテオミクス / 抗がん剤 / ゲノム薬理 / プロテオーム / 薬剤性中枢神経障害 / 白血病幹細胞 / 疾患モデル / NSGマウス / DNA修復機構 / ALL / MLL / 異種移植 / NSGマウス / 次世代シークエンサー / 発現プロファイル / エクソーム解析 / 発現アレイ / アレイCGH / 急性白血病 / ETV6遺伝子 / 胚細胞変異 / 家族性 / BCR/ABL / DNA損傷応答 / 小児血液学 / T細胞受容体 / C/EBPα / 神経幹細胞 / iPS細胞 / 脂肪細胞 / 毛細血管拡張性運動失調症 / ATM / PARP阻害剤 / 小児腫瘍学 / MYC / 翻訳開始因子群 / 炭素骨格分子 / 癌細胞代謝 / アポトーシス / alpha-ケトグルタル酸 / NK細胞腫瘍 / TCAサイクル / グルタミン / eIF4E / NK細胞リンパ腫 / L-asparaginase / 造血幹細胞 / 染色体転座 / TopoII阻害剤 / 母体環境 / 免疫学的寛容 / NIMA / Phクローン / 胎児 / BCR/ABL1 / DNA damage / LOH / γδT細胞 / CML / ABL / BCR Less
  • Research Projects

    (16 results)
  • Research Products

    (107 results)
  • Co-Researchers

    (33 People)
  •  核内ゲノム3D構造からみた乳児急性リンパ性白血病の病態解明および治療法開発Principal Investigator

    • Principal Investigator
      高木 正稔
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Institute of Science Tokyo
  •  非コードRNA転写による脱メチル化制御とスーパーエンハンサー活性化機構の解明

    • Principal Investigator
      磯田 健志
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Institute of Science Tokyo
  •  Identification of the cell of origin of infant leukemia with pluripotency

    • Principal Investigator
      Goyama Susumu
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      The University of Tokyo
  •  Mechanistic Insights into Non-Coding RNA Transcription and Super-Enhancer Activation via Control Region Mutations

    • Principal Investigator
      Isoda Takeshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Genetic background of acute lymphoblastic leukemia in childrenPrincipal Investigator

    • Principal Investigator
      Takagi Masatoshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Epidemiological investigation of risk factors for childhood leukemia onset and adverse effects among survivors

    • Principal Investigator
      Urayama Kevin
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      National Center for Child Health and Development
  •  Analysis for pathogenesis of drug-induced neurotoxicity by using pharmacogenomics and proteomics technique.

    • Principal Investigator
      Yanagimachi Masakatsu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tokyo Medical and Dental University
  •  Understanding of MLL-related leukemogenesis and identification of new therapeutic targets

    • Principal Investigator
      Aoki Yuki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of carcinogenesis based on TCR rearrangement systemPrincipal Investigator

    • Principal Investigator
      Takagi Masatoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification of causative genes in familial acute lymphoblastic leukemia

    • Principal Investigator
      Moritake Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      University of Miyazaki
  •  Development of therapeutic approach targeting DNA damage check point

    • Principal Investigator
      SHUKI Mizutani
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of glucose intolerance in Ataxia TelangiectasiaPrincipal Investigator

    • Principal Investigator
      TAKAGI Masatoshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of cell differentiation machinery regulated by ATM

    • Principal Investigator
      PIAO Jinhua
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of the mechanism of L-asparaginase to suppress the highly expressed eIF4E in NK-cell lymphoma

    • Principal Investigator
      SUGIMOTO Koichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Juntendo University
  •  Pediatric hematological disorder caused by in utero facors

    • Principal Investigator
      MIZUTANI Shuuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  遺伝性毛細血管拡張性小脳失調症責任遺伝子ATMと糖代謝、翻訳制御に関する研究Principal Investigator

    • Principal Investigator
      高木 正稔
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      International University of Health and Welfare

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2006 Other

All Journal Article Presentation

  • [Journal Article] Intracranial residual lesions following early intensification in a patient with T-cell acute lymphoblastic leukemia: a case report2024

    • Author(s)
      Nagamatsu Yuichi、Isoda Takeshi、Inaji Motoki、Oyama Jun、Niizato Daiki、Tomomasa Dan、Mitsuiki Noriko、Yamashita Motoi、Kamiya Takahiro、Imai Kohsuke、Kanegane Hirokazu、Morio Tomohiro、Takagi Masatoshi
    • Journal Title

      BMC Pediatrics

      Volume: 24 Issue: 1

    • DOI

      10.1186/s12887-024-04790-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08560, KAKENHI-PROJECT-24K02417
  • [Journal Article] Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type2023

    • Author(s)
      Nishimura Akira、Yokoyama Kazuaki、Naruto Takuya、...、Ishida Yasushi、Takita Junko、Ishikawa Fumihiko、Goto Hiroaki、Morio Tomohiro、Mizutani Shuki、Tojo Arinobu、Takagi Masatoshi
    • Journal Title

      Science Advances

      Volume: 9 Issue: 50 Pages: 50-50

    • DOI

      10.1126/sciadv.adj4407

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08419, KAKENHI-PROJECT-21H02878
  • [Journal Article] Novel variants for Glanzmann thrombasthenia manifesting with purpura at birth2022

    • Author(s)
      Eguchi Shiori、Isoda Takeshi、Yamaguchi Asuka、Takagi Masatoshi
    • Journal Title

      Pediatrics International

      Volume: 64 Issue: 1

    • DOI

      10.1111/ped.15149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02878
  • [Journal Article] Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study2022

    • Author(s)
      Hoshino A, Toyofuku E, Mitsuiki N, Yamashita M, Okamoto K, Yamamoto M, Kanda K, Yamato G, Keino D, Yoshimoto-Suzuki Y, Kamizono J, Onoe Y, Ichimura T, Nagao M, Yoshimura M, Tsugawa K, Igarashi T, Mitsui-Sekinaka K, Sekinaka Y, Doi T, Yasumi T, Nakazawa Y, Takagi M, Imai K, Nonoyama S, Morio T, Latour S, Kanegane H.
    • Journal Title

      Frontiers in Immunology

      Volume: 12 Pages: 784901-784901

    • DOI

      10.3389/fimmu.2021.784901

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K22916, KAKENHI-PROJECT-19H03614, KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-20K16942
  • [Journal Article] Case report: Optimized ruxolitinib-based therapy in an infant with familial hemophagocytic lymphohistiocytosis type 32022

    • Author(s)
      Niizato Daiki、Isoda Takeshi、Mitsuiki Noriko、Kaneko Shuya、Tomomasa Dan、Kamiya Takahiro、Takagi Masatoshi、Imai Kohsuke、Kajiwara Michiko、Shimizu Masaki、Morio Tomohiro、Kanegane Hirokazu
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 977463-977463

    • DOI

      10.3389/fimmu.2022.977463

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02878
  • [Journal Article] Characteristics of Li‐Fraumeni Syndrome in Japan; A Review Study by the Special Committee of JSHT2021

    • Author(s)
      Funato M.、Tsunematsu Y.、Yamazaki F.、Tamura C.、Kumamoto T.、Takagi M.、Kato S.、Sugimura H.、Tamura K.
    • Journal Title

      Cancer Science

      Volume: - Issue: 7 Pages: 2821-2834

    • DOI

      10.1111/cas.14919

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07740, KAKENHI-PROJECT-19K07763, KAKENHI-PROJECT-19H03614
  • [Journal Article] <i>NUDT15</i> variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia2021

    • Author(s)
      Yoshida Masanori,Nakabayashi Kazuhiko,Yang Wentao,Sato-Otsubo Aiko,Tsujimoto Shin-ichi, Motohiro Kato et al
    • Journal Title

      Blood Advances

      Volume: 5 Issue: 23 Pages: 5420-5428

    • DOI

      10.1182/bloodadvances.2021005507

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16762, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03614, KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-21K06143
  • [Journal Article] A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS2021

    • Author(s)
      Yamashita Motoi、Kuehn Hye Sun、Okuyama Kazuki、Okada Satoshi、Inoue Yuzaburo、Takagi Masatoshi、Kanegane Hirokazu、Takeuchi Masahiro、Shimojo Naoki、Tsumura Miyuki、Padhi Aditya K.、Zhang Kam Y. J.、Boisson Bertrand、Casanova Jean-Laurent、Ohara Osamu、Rosenzweig Sergio D.、Taniuchi Ichiro、Morio Tomohiro
    • Journal Title

      Nature Immunology

      Volume: 22 Issue: 7 Pages: 893-903

    • DOI

      10.1038/s41590-021-00951-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05747, KAKENHI-PROJECT-19H03614, KAKENHI-PROJECT-19H03620, KAKENHI-PROJECT-21H02879, KAKENHI-PROJECT-20K07459, KAKENHI-PROJECT-20K08158, KAKENHI-PROJECT-20K16884
  • [Journal Article] Successful ruxolitinib administration for a patient with steroid‐refractory idiopathic pneumonia syndrome following hematopoietic stem cell transplantation: A case report and literature review2021

    • Author(s)
      Tomomasa Dan、Isoda Takeshi、Mitsuiki Noriko、Yamashita Motoi、Morishita Aoi、Tomoda Takahiro、Okano Tsubasa、Endo Akifumi、Kamiya Takahiro、Yanagimachi Masakatsu、Imai Kohsuke、Kanegane Hirokazu、Takagi Masatoshi、Morio Tomohiro
    • Journal Title

      Clinical Case Reports

      Volume: 9 Issue: 12 Pages: 1-9

    • DOI

      10.1002/ccr3.5242

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02878, KAKENHI-PROJECT-20K16437
  • [Journal Article] Genomics analysis of leukaemia predisposition in X‐linked agammaglobulinaemia2021

    • Author(s)
      Nishimura, A. Naruto, T. Miyamoto, S. Grigg, A. Bosco, J. J. Hoshino, A. Amano, K. Iwamoto, S. Hirayama, M. Migita, M. Ohara, O. Takagi, M. Morio, T. van Zelm, M. C. Kanegane, H.
    • Journal Title

      British Journal of Haematology

      Volume: 193 Issue: 6 Pages: 1277-1281

    • DOI

      10.1111/bjh.17459

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Journal Article] Functional characterization of a germline ETV6 variant associated with inherited thrombocytopenia, acute lymphoblastic leukemia, and salivary gland carcinoma in childhood2020

    • Author(s)
      Yoshino Hiroshi、Nishiyama Yohei、Kamma Hiroshi、Chiba Tomohiro、Fujiwara Masachika、Karaho Takehiro、Kogashiwa Yasunao、Morio Tomohiro、Yan Kunimasa、Bessho Fumio、Takagi Masatoshi
    • Journal Title

      International Journal of Hematology

      Volume: 112 Issue: 2 Pages: 217-222

    • DOI

      10.1007/s12185-020-02885-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Journal Article] Prevalence of germline GATA2 and SAMD9/9L variants in paediatric haematological disorders with monosomy 72020

    • Author(s)
      Yoshida, M. Tanase-Nakao, K. Shima, H. Shirai, R. Yoshida, K. Osumi, T. Deguchi, T. Mori, M. Arakawa, Y. Takagi, M. Miyamura, T. Sakaguchi, K. Toyoda, H. Ishida, H. Sakata, N. Imamura, T. Kawahara, Y. Morimoto, A. Koike, T. Yagasaki, H. Ito, S. Tomizawa, D. Kiyokawa, N. Narumi, S. Kato, M.
    • Journal Title

      British Journal of Haematology

      Volume: 191 Issue: 5 Pages: 835-843

    • DOI

      10.1111/bjh.17006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03614, KAKENHI-PROJECT-19H03627, KAKENHI-PROJECT-20H03653, KAKENHI-PROJECT-18J21048, KAKENHI-PROJECT-19K22608
  • [Journal Article] HLA haploidentical hematopoietic cell transplantation using clofarabine and busulfan for refractory pediatric hematological malignancy.2017

    • Author(s)
      Takagi M, Ishiwata Y, Aoki Y, Miyamoto S, Hoshino A, Matsumoto K, Nishimura A, Tanaka M, Yanagimachi M, Mitsuiki N, Imai K, Kanegane H, Kajiwara M, Takikawa K, Mae T, Tomita O, Fujimura J, Yasuhara M, Tomizawa D, Mizutani S, Morio T.
    • Journal Title

      Int J Hematol

      Volume: 105 Issue: 5 Pages: 686-691

    • DOI

      10.1007/s12185-017-2187-3

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461570, KAKENHI-PROJECT-15K19601, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10099
  • [Journal Article] MLL転座型ヒト急性リンパ性白血病におけるleukemia initiating cellsの同定2016

    • Author(s)
      青木由貴, 高木 正稔, 小野 林太郎, 水谷 修紀, 石川 文彦
    • Journal Title

      血液内科

      Volume: 72 Pages: 231-236

    • NAID

      40020749788

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19601
  • [Journal Article] Haploidentical Bone Marrow Transplantation With Clofarabine and Busulfan Conditioning for a Child With Multiple Recurrent Acute Lymphoblastic Leukemia.2016

    • Author(s)
      Aoki Y, Miyawaki R, Imai K, et al.
    • Journal Title

      J Pediatr Hematol Oncol.

      Volume: 38(1) Issue: 1 Pages: e39-e41

    • DOI

      10.1097/mph.0000000000000454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461567, KAKENHI-PROJECT-15K19601
  • [Journal Article] Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells2015

    • Author(s)
      Nanya, M. Sato, M. Tanimoto, K. Tozuka, M. Mizutani, S. Takagi, M.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 12 Pages: e0144540-e0144540

    • DOI

      10.1371/journal.pone.0144540

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461580
  • [Journal Article] ATM(ataxia telangiectasia mutated)2015

    • Author(s)
      高木正稔
    • Journal Title

      日本臨床

      Volume: 73 Pages: 263-269

    • Data Source
      KAKENHI-PROJECT-25461580
  • [Journal Article] DNA損傷応答異常症(Ataxia Telangiectasiaを含めて)2015

    • Author(s)
      高木正稔
    • Journal Title

      小児内科

      Volume: 47 Pages: 691-696

    • Data Source
      KAKENHI-PROJECT-25461580
  • [Journal Article] ATM and SIRT6/SNF2H mediate transient H2AX stabilization when DSBs form by blocking HUWE1 to allow efficient γH2AX foci formation.2015

    • Author(s)
      Atsumi, Y., Minakawa, Y., Ono, M., Dobashi, S., Snohe, K., Shinohara, A., Takeda, S., Takagi, M., Takamatsu, N., Nakagama, H., Teraoka, H., and K.-I. Yoshioka
    • Journal Title

      Cell Reports

      Volume: 13 Issue: 12 Pages: 2728-2740

    • DOI

      10.1016/j.celrep.2015.11.054

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22125001, KAKENHI-PROJECT-13J10618, KAKENHI-PROJECT-25461580, KAKENHI-PROJECT-26650007, KAKENHI-PLANNED-15H05973
  • [Journal Article] Hematopoietic myeloid cell differentiation diminishes nucleotide excision repair2014

    • Author(s)
      Aoki, Y. Sato, A. Mizutani, S. Takagi, M.
    • Journal Title

      Int J Hematol

      Volume: 100 Issue: 3 Pages: 260-5

    • DOI

      10.1007/s12185-014-1625-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461580
  • [Journal Article] Artemis-dependent DNA double-strand break formation at stalled replication forks.2013

    • Author(s)
      Unno J, Takagi M, Piao J, Sugimoto M, Honda F, Maeda D, Masutani M, Kiyono T, Watanabe F, Morio T, Teraoka H, Mizutani S.
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 6 Pages: 703-10

    • DOI

      10.1111/cas.12144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390270, KAKENHI-PROJECT-23390271, KAKENHI-PROJECT-24590368
  • [Journal Article] Successful treatment of diffuse large B cell lymphoma in a patient with ataxia telangiectasia using rituximab2013

    • Author(s)
      Machida S, Tomizawa D, Tamaichi H, Okawa T, Endo A, Imai K, , Nagasawa M, Morio T, Mizutani S, Takagi M
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 36 Issue: 6 Pages: 482-485

    • DOI

      10.1097/mph.0b013e3182804d59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Journal Article] ATM-dependent DNA damage-response pathway as a determinant in Chronic Myelogenous Leukemia2013

    • Author(s)
      Takagi M, Sato M, Piao J, Miyamoto S, Isoda T, Kitagawa M, Honda H, Mizutani S
    • Journal Title

      DNA Repair

      Volume: 12(7) Issue: 7 Pages: 500-507

    • DOI

      10.1016/j.dnarep.2013.04.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390271, KAKENHI-PROJECT-24590476
  • [Journal Article] Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor2013

    • Author(s)
      Tamaichi H, Sato M, Porter AC, Shimizu T, Mizutani S, Takagi M
    • Journal Title

      Cancer Sci

      Volume: 104(2) Issue: 2 Pages: 178-184

    • DOI

      10.1111/cas.12067

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Journal Article] Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM2012

    • Author(s)
      Isoda T, Takagi M, Piao J, Nakagama S,Sato M, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S
    • Journal Title

      Blood

      Volume: 120(4) Issue: 4 Pages: 789-9

    • DOI

      10.1182/blood-2012-02-413195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591121, KAKENHI-PROJECT-23390270, KAKENHI-PROJECT-23390271, KAKENHI-PROJECT-24249057, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24790486, KAKENHI-PLANNED-22118004
  • [Journal Article] AtaxiaTelangiectasiaにおけるミトコンドリア異常2012

    • Author(s)
      金子節子,高木正稔
    • Journal Title

      血液内科

      Volume: 65(6) Pages: 825-31

    • NAID

      40019555246

    • Data Source
      KAKENHI-PROJECT-22591121
  • [Journal Article] 毛細血管拡張性運動失調症Ataxia Telangiectasiaと関連疾患2012

    • Author(s)
      高木正稔
    • Journal Title

      メディカル・サイエンス・ダイジェスト

      Volume: 38(1) Pages: 17-20

    • Data Source
      KAKENHI-PROJECT-22591121
  • [Journal Article] Activation of the Activin A-ALK-Smad Pathway in Systemic Sclerosis2011

    • Author(s)
      Takagi K, 他
    • Journal Title

      J Autoimmunity

      Volume: 26 Pages: 181-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Journal Article] Autoimmune lymphoproliferative syndrome-like disease with somatic KRAS mutation2011

    • Author(s)
      Takagi M, 他
    • Journal Title

      Blood

      Volume: 117 Pages: 2887-2892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Journal Article] DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development.2010

    • Author(s)
      Ichijima Y, Yoshioka K, Yoshioka Y, Shinohe K, Fujimori H, Unno J, Takagi M, Goto H, Inagaki M, Mizutani S, Teraoka H.
    • Journal Title

      PLoS One.

      Volume: 5 Pages: 8821-8821

    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Pharmacokinetic monitoring is still required for intravenous busulfan in SCT for small children International2010

    • Author(s)
      Nagasawa M, Noriko Mitsuiki, Toshiaki Ono, Masatoshi Takagi, Hiromi Oda, Masato Yasuhara, Shuki Mizutani
    • Journal Title

      Journal of Hematology

      Volume: 91 Pages: 728-730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Attenuation of p53 accumulation after irradiation in cells with C465T polymorphism.2010

    • Author(s)
      Sato M, Takagi M, Mizutani S
    • Journal Title

      J Med Dent Sci. 57

      Pages: 139-145

    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Autopsy study of cerebellar degeneration in siblings with ataxia-telangiectasia-like disorder.2010

    • Author(s)
      Oba D, Hayashi M, Minamitani M, Hamano S, Uchisaka N, Kikuchi A, Kishimoto H, Takagi M, Morio T, Mizutani S.
    • Journal Title

      Acta Neuropathol.

      Volume: 119 Pages: 513-520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Pharmacokinetic monitoring is still required for intravenous busulfan in SCT for small children.2010

    • Author(s)
      Nagasawa M, Mitsuiki N, Ono T, Takagi M, Oda H, Yasuhara M, Mizutani S.
    • Journal Title

      Int JHematol.

      Volume: 91 Pages: 728-30

    • NAID

      10026402408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] T ranscription-dependent activation of ataxia telangiectasia-mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase Ipoison.2010

    • Author(s)
      Sakasai R, Teraoka H, Takagi M, Tibbetts RS.
    • Journal Title

      JBiol Chem.

      Volume: 285 Pages: 15201-15208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Autoimmune phenomena in Noonan syndrome ; a possible link with RALD.2010

    • Author(s)
      Mizutani S, Takagi M.
    • Journal Title

      Blood.e-letter.

    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Autoimmune lymphoproliferative syndrome-like disease with somatic KRAS mutation.2010

    • Author(s)
      Takagi M, Mizutani S, et al.
    • Journal Title

      Blood

      Volume: 117 Pages: 2887-2890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Attenuation of p53 accumulation after irradiation in cells with C465T polymorphism.2010

    • Author(s)
      Sato M, Takagi M, Mizutani S.
    • Journal Title

      J Med Dent Sci.

      Volume: 57 Pages: 139-145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Autoimmune phenomena in Noonan syndrome; a possible link with RALD.2010

    • Author(s)
      Mizutani S, Takagi M.
    • Journal Title

      Blood.

      Volume: (e-letter)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Autoimmune Lymphoproliferative Syndrome Like Disease With Somatic KRAS Mutation.2010

    • Author(s)
      Takagi M, Mizutani S, et al.
    • Journal Title

      Blood Nov 9(Epub ahead of print.)

    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] Rapid diagnosis of ataxia-telangiectasia by flow cytometric monitoring of DNA damage-dependent ATM phosphorylation.2009

    • Author(s)
      Honda M, Takagi M, Chessa L, Morio T, Mizutani S
    • Journal Title

      Leukemia. 23

      Pages: 409-414

    • Data Source
      KAKENHI-PROJECT-20390302
  • [Journal Article] ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome2006

    • Author(s)
      Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, Semenkovich CF
    • Journal Title

      Cell Metabolism 4

      Pages: 377-389

    • Data Source
      KAKENHI-PROJECT-18659306
  • [Presentation] Non-coding RNA transcription and super-enhancer activation facilitate 3D genome structure2023

    • Author(s)
      1.Akira Nishimura, Makiko Sasaki, Riski Muhaimin, Yukie Tanaka, Tomohiro Morio, Masatoshi Takagi, Takeshi Isoda
    • Organizer
      The 14th International Workshop on Advanced Genomics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02878
  • [Presentation] 非コードRNA転写とスーパーエンハンサー活性化によるゲノムの3次元構造維持機構2022

    • Author(s)
      4.西村聡、佐々木麻起子、高木正稔、磯田健志
    • Organizer
      第81回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02878
  • [Presentation] Pediatric acute lymphoblastic leukemia predisposition caused by germline variants in the PAX5 gene2021

    • Author(s)
      Masatoshi Takagi
    • Organizer
      Final meeting EU-COST Action LEGEND
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] Characteristics of Li-Fraumeni Syndrome in Japan; A Review Study by the Special Committee of the JSHT2021

    • Author(s)
      Funato M Tsunematsu Y Yamazaki F Tamura C Kumamoto T Takagi M Kato S Sugimura H Tamura K
    • Organizer
      第80回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] X連鎖無ガンマグロブリン血症における白血病発症因子のゲノム解析2020

    • Author(s)
      西村聡,成戸卓也,星野顕宏,天野敬史郎,岩本彰太郎,平山雅治,Andrew Grigg,Julian J.Bosco,右田昌宏,高木正稔,小原収,森尾友宏,Menno C.van Zelm,金兼弘和
    • Organizer
      第3回日本免疫不全・自己炎症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] 小児期にホジキンリンパ種を発症し、成人後に免疫グロブリン低下を指摘されALPS-FASと診断された一例2020

    • Author(s)
      Yohei Nishiyama, Etsushi Toyofuku, Tsubasa Okano, Motoi Yamashita, Takahiro Kamiya, Akifumi Endo, Hirokazu Kanegane, Masatoshi Takagi, Kohsuke Imai, Tomohiro Morio
    • Organizer
      第62回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] Association of Germline Variants of TCF3 and PAX5 with Pediatric Acute Lymphoblastic Leukemia Development2019

    • Author(s)
      Miyamoto,S. Naruto,T. Morio, T. Urayama,KY Manabe, A. Takagi,M.
    • Organizer
      61st American Society of Hematology (ASH) Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] 小児のモノソミー7を伴う血液疾患における生殖細胞系列のSAMD9/9Lバリアント保有率2019

    • Author(s)
      吉田仁典, 中尾佳奈子, 島彦仁, 白井了太, 吉田馨, 辻本信一, 大隅朋生, 出口隆生4, 森麻希子5, 荒川ゆうき, 高木正稔, 宮村能子, 坂口公祥, 豊田秀実, 石田悠志, 坂田尚己, 今村俊彦, 川原勇太, 小池隆志, 富澤大輔, 清河信敬, 鳴海覚志, 加藤元博
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] Genomics Analysis of Leukemia Predisposition in X-Linked Agammaglobulinemia2019

    • Author(s)
      Nishimura A, Naruto T, Hoshino A, Amano K, Iwamoto S, Hirayama M, Grigg A, Bosco J J, Migita M, Takagi M, Ohara O, Morio T, van Zelm MC, Kanegane H
    • Organizer
      19th Biennial Meeting of the European Society of Immunodeficiencies (ESID2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] 遺伝性素因と白血病2019

    • Author(s)
      高木正稔
    • Organizer
      第12回研修医(初期・後期)のための血液学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children2019

    • Author(s)
      Yoshida, M. Nakabayashi, K. Sato-Otsubo, A. Tsujimoto, S. Yoshida, K. Shirai, R. Osumi, T. Yuza, Y. Takagi, M. Takahashi, H. Koh,K. Kinoshita, A. Hino, M. Imamura, T. Nakazawa, Y. Okuya, M. Kakuda, H. Sanada, M. Matsumoto, K. Tomizawa, D. Kiyokawa, N. Ohara, A. Manabe, A. Hata, K. Yang, J, J. Kato, M.
    • Organizer
      61st American Society of Hematology (ASH) Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03614
  • [Presentation] Xenograftを用いた乳児期発症のMLL白血病の病態理解2015

    • Author(s)
      青木 由貴、小野 林太郎、佐藤 馨、高木 正稔、水谷 修紀、石川 文彦
    • Organizer
      第11回麒麟塾
    • Place of Presentation
      コクヨホール(東京都港区)
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-15K19601
  • [Presentation] Sensitivity to PARP inhibitor in acute lymphoblastic leukemia2013

    • Author(s)
      Masatoshi Takagi, Jinhua Piao, Takahiro Kamiya, Takeshi Inukai, Kanji Sugita, Kazuma Ohyashiki, Mitsuko Masutani, Shuki Mizutani
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌市、北海道
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] ATM-dependent DNA damage-response pathway as a determinant in Chronic Myelogenous Leukemia2013

    • Author(s)
      Takagi M, Mizutani S
    • Organizer
      ATW2013
    • Place of Presentation
      Birmingham, UK
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] 毛細血管拡張性運動失調症-原発性免疫不全症から血液悪性腫瘍発症機構に迫る-2013

    • Author(s)
      高木正稔
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌市、北海道
    • Data Source
      KAKENHI-PROJECT-25461580
  • [Presentation] E2A-HLF陽性急性リンパ性白血病に対するPARP阻害剤の有効性2013

    • Author(s)
      高木正稔, 益谷美都子, 水谷修紀
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市、神奈川県
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] T-Cell Development Failure At β-Selection Checkpoint and TCRα/δ Locus Break Formation Associated with Chromosome 14 Translocation in Ataxia-Telangiectagia Mutated Deficient Mice2012

    • Author(s)
      Isoda T, Takagi M, Piao J, Nakagama S, Sato M, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S
    • Organizer
      53rd American society of hematology, annual meeting
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] ATM and haploinsufficiency acceleration of cancer development. International symposium 50th Anniversary of RIRBM2012

    • Author(s)
      Sato M, Takagi M, Piao J, Isoda1 T, Honda H, Yasuda A, Mizutani S
    • Organizer
      Hiroshima University
    • Place of Presentation
      Hiroshima
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] Visualization of chromosomal translocation and early T-cell development failure in ATM deficiency2012

    • Author(s)
      Isoda1 T, Takagi M, Piao J, Sato M, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S
    • Organizer
      14th International workshop on Ataxia Telangiectasia
    • Place of Presentation
      Delhi, India
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] 慢性骨髄性白血病 急性転化におけるDNA損傷応答機構の関与2012

    • Author(s)
      高木正稔
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23390271
  • [Presentation] Derivation of neural stem cell via iPS cell from ataxia telangiectasia2012

    • Author(s)
      Kaneko S, Takagi M, Fukawatase Y, Umezawa A, Mizutani S
    • Organizer
      14th International workshop on Ataxia Telangiectasia
    • Place of Presentation
      Delhi, India
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] ATM欠損T細胞分化のDN期におけるTリンパ球減少の原因と染色体転座の関係2012

    • Author(s)
      磯田健志,高木正稔,朴今花,増田喬子,伊川友活,東みゆき,森尾友宏,河本宏,水谷修紀
    • Organizer
      第115回日本小児科学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] Visualization of chromosomal translocation and early T-cell development failure in ATM deficiency2012

    • Author(s)
      Isoda T, Takagi, M, Piao J, Sato M, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S
    • Organizer
      14th International workshop on AtaxiaTelangiectasia
    • Place of Presentation
      Delhi, India
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] 毛細血管運動失調症の Double Negative 期におけるT リンパ球分化異常と発がんメカニズムの関係2011

    • Author(s)
      磯田健志,高木正稔,朴今花,増田喬子,井川友活,東みゆき,森尾友宏,河本宏,水谷修紀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] DN3 T-cell development failurein Ataxia telangiectagia (AT)2011

    • Author(s)
      Isoda T, Takagi M, Piao J, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] 毛細血管拡張性小脳失調症(AtaxiaTelangiectagia)におけるT細胞分化異常の解析2011

    • Author(s)
      磯田健志,高木正稔,森尾友宏,水谷修紀
    • Organizer
      日本臨床免疫学会会誌
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] T-Cell Development Failure At β-Selection Checkpoint and TCRα/δ Locus Break Formation Associated with Chromosome 14Translocation in Ataxia-Telangiectagia Mutated Deficient Mice2011

    • Author(s)
      Isoda T, Takagi M, Piao J, Nakagama S, Sato M, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S
    • Organizer
      53^<rd> American society of hematology, annual meeting
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] 緑膿菌菌血症および深在性真菌感染症に対して顆粒球輸血を行ったFanconi貧血の1例2010

    • Author(s)
      堀越愛那, 小野敏明, 富澤大輔, 梶原道子, 長澤正之, 高木正稔, 森尾友宏, 水谷修紀
    • Organizer
      第12回小児医療セミナー
    • Place of Presentation
      東京
    • Year and Date
      2010-09-18
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] p190型BCR-ABL白血病における母子間転移と非遺伝性HLA(NIMA)欠損2010

    • Author(s)
      磯田健志, 満生紀子, 青木由貴, 富澤大輔, 高木正稔, 長澤正之, 森尾友宏, 落合央, 滝智彦, 佐治博夫, 水谷修紀
    • Organizer
      第7回北関東小児がんセミナー
    • Place of Presentation
      群馬
    • Year and Date
      2010-05-15
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 母体から子へ白血病細胞が移行した機序の解明2010

    • Author(s)
      磯田健志, 満生紀子, 青木由貴, 富澤大輔, 高木正稔, 長澤正之, 森尾友宏, 落合央, 滝智彦, 佐治博夫, 水谷修紀
    • Organizer
      東京医科歯科大学小児科同窓会口演
    • Place of Presentation
      東京
    • Year and Date
      2010-06-05
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 寛解導入療法中にクモ膜化出血を起こした急性リンパ球性白血病の1例2010

    • Author(s)
      小野敏明, 大川哲平, 遠藤明史, 富澤大輔, 高木正稔, 梶原道子, 武川麻紀, 前原健寿, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] T細胞リンパ腫とAtmハプロ不全~BCRABLトランスジェニックマウスを用いた解析~2010

    • Author(s)
      佐藤正樹, 高木正稔, 朴今花, 本田博章, 安田章夫, 水谷修紀
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 造血幹細胞移植における新規「DIC・微小血管障害の臨床スコア」作成とその有効性・有用性の後方視的検討2010

    • Author(s)
      長澤正之, 大川哲平, 遠藤明史, 満生紀子, 青木由貴, 小野敏明, 磯田健志, 富澤大輔, 高木正稔, 梶原道子, 森尾友宏, 水谷修紀
    • Organizer
      第52回日本小児血液学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-18
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] RAS associated ALPS like disease2010

    • Author(s)
      高木正稔
    • Organizer
      関東甲越免疫不全症研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] RAS associated ALPS like disease.2010

    • Author(s)
      高木正稔
    • Organizer
      関東甲越免疫不全症研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 4人の悪性リンパ腫の家族歴を有する小児濾胞性リンパ腫の1例2010

    • Author(s)
      森真理, 篠田邦大, 西澤茉莉, 横山能文, 門井絵美, 大西沙織理, 高木正稔, 高尾明
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] KRAS変異を持つALPS様疾患の1例-is there any sequentiality between ALPS andJMML?-2010

    • Author(s)
      高木正稔, 満生紀子, 遠藤明史, 小野敏明, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀, 小池健一
    • Organizer
      第17回小児再生不良性貧血治療研究会 第15回小児MDS治療研究会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] DNA複製障害時の重傷複合型免疫不全症責任遺伝子Artemisの持つ役割についての解析2010

    • Author(s)
      高木正稔
    • Organizer
      第3回日本免疫不全症研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-01-30
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] 応答機構と白血病2010

    • Author(s)
      高木正稔
    • Organizer
      第53回日本放射線影響学会大会シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] KRAS変異を持つALPS様疾患の1例-Is there any sequentiality between ALPS and JMML2010

    • Author(s)
      高木正稔
    • Organizer
      第17回小児再生不良性貧血治療研究会、第15回小児MDS治療研究会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] ATM regulates adiopocyte differentiation.2010

    • Author(s)
      Masatoshi Takagi, Hatsume Uno, Masataka Sugimoto, Akio Yasuda, Shuki Mizutani.
    • Organizer
      ATW2010
    • Place of Presentation
      USA.Los Angels.
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 2歳時に急性巨核芽球性白血病を発症後、6年後にB前駆細胞型急性リンパ性白血病を発症したダウン症候群の1例2010

    • Author(s)
      秋山めぐみ, 遠藤明史, 富澤大輔, 大川哲平, 高木正稔, 小野敏明, 長澤正之, 森尾友宏, 水谷修紀, 梶原道子
    • Organizer
      第575回日本小児科学会東京都地方会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] リンパ節腫脹、肝脾腫、自己抗体を産生し、KRAS体細胞変異をみとめた乳児例2010

    • Author(s)
      満生紀子, 高木正稔, 遠藤明史, 小野敏明, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第112回小児血液腫瘍懇話会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 造血幹細胞移植後の生着前凝固障害に対してリコンビナント・トロンボモジュリンを使用した3例2010

    • Author(s)
      大川哲平, 遠藤明史, 満生紀子, 青木由貴, 小野敏明, 磯田健志, 富澤大輔, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第16回小児H-SCT研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 非定型抗酸菌と結核菌群による播種性全身感染症を呈した外胚葉形成不全免疫不全症候群の1例2010

    • Author(s)
      大川哲平, 遠藤明史, 小野敏明, 富澤大輔, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第42回日本小児感染症学会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 造血幹細胞移植における「新規DIC・微小血管障害の臨床スコア」作成とその有効性・有用性の後方視的検討2010

    • Author(s)
      長澤正之, 大川哲平, 遠藤明史, 満生紀子, 青木由貴, 小野敏明, 磯田健志, 富澤大輔, 高木正稔, 梶原道子, 水谷修紀
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] ATM regulate adipocyte differentiation.2010

    • Author(s)
      烏野初萌, 高木正稔, 杉本昌隆, 安田章夫, 水谷修紀
    • Organizer
      第33回分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 母体から子へ白血病細胞が移行した機序の解明2010

    • Author(s)
      磯田健志, 満生紀子, 青木由貴, 富澤大輔, 高木正稔, 長澤正之, 森尾友宏, 落合央, 滝智彦, 佐治博夫, 水谷修紀
    • Organizer
      東京医科歯科大学医師会賞授賞口演
    • Place of Presentation
      東京
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 2歳時に急性巨核芽球性白血病を発症後、6年後にB前駆細胞型急性リンパ性白血病を発症したダウン症候群の1例2010

    • Author(s)
      遠藤明史, 富澤大輔, 大川哲平, 小野敏明, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      日本小児科学会東京都地方会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] シクロスポリン1日3回投与で血中濃度を維持した急性リンパ性白血病の1例2010

    • Author(s)
      大川哲平, 遠藤明史, 小野敏明, 富澤大輔, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] In vivo study of human MLL-rearranged acute lymphoblastic leukemia.2010

    • Author(s)
      Yuki Aoki, Yoriko Saito, NahokoSuzuki, Akiko Sone, Mariko Tomizawa, Yuho Najima, Shinsuke Takagi, Satoshi Tanaka, Leonard D.Shultz, Shuki Mizutani, Fumihiko Ishikawa.
    • Organizer
      Noyori Summer School.
    • Place of Presentation
      Aioi
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 診断時よりBCG感染によると思われる全身性の紅斑を認め、移植後発熱が遷延したX連鎖性重症複合免疫不全症の2例2010

    • Author(s)
      小野敏明, 大川哲平, 遠藤明史, 満生紀子, 富澤大輔, 今井雅子, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第42回日本小児感染症学会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] DNA損傷応答機構と白血病2010

    • Author(s)
      高木正稔
    • Organizer
      第53回日本放射線影響学会大会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] RICによる非血縁者間骨髄移植を行った先天性角化異常症の臨床経過2010

    • Author(s)
      大川哲平, 満生紀子, 遠藤明史, 小野敏明, 磯田健志, 富澤大輔, 高木正稔梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第7回JPLSG研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-20
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] MYH9-ALK : Anaplastic large cell lymphomaにおける稀なALK融合遺伝子の同定2010

    • Author(s)
      津山直子, 冨樫由紀, 倉田盛人, 波多野郷子, 青木由貴, 小野敏明, 磯田健志, 高木正稔, 水谷修紀, 北川昌伸, 竹内賢吾
    • Organizer
      第50回日本リンパ網内系学会総会
    • Place of Presentation
      新潟
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 造血幹細胞移植後の生着前凝固異常に対してリコンビナント・トロンボモジュリンを使用した3例2010

    • Author(s)
      足洗美穂, 大川哲平, 遠藤明史, 満生紀子, 青木由貴, 小野敏明, 磯田健志, 富澤大輔, 高木正稔, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第16回小児H-SCT研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] ATM regulates cell differentiation2010

    • Author(s)
      Masatoshi Takagi
    • Organizer
      第33回分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] ATM regulates cell differentiation.2010

    • Author(s)
      Masatoshi Takagi, Hatsume Uno, Takeshi Isoda, Masataka Sugimoto, Akio Yasuda, Shuki Mizutani.
    • Organizer
      第33回分子生物学会年会第83回日本生化学会大会合同大会ワークショップ
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] KRAS変異自己免疫性リンパ球増殖症候群2010

    • Author(s)
      高木正稔
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] リンパ節腫脹、肝脾腫、自己抗体を産生し、KRAS体細胞変異をみとめた乳児例2010

    • Author(s)
      満生紀子, 高木正稔, 遠藤明史, 小野敏明, 梶原道子, 長澤正之, 森尾友宏, 水谷修紀
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] KRAS変異自己免疫性リンパ球増殖症候群2010

    • Author(s)
      高木正稔, 篠田邦大, 満生紀子, 朴今花, 高木真理, 松田和之, 村松秀城, 土居崎小夜子, 長澤正之, 森尾友宏, 小池健一, 小島勢二, 高尾明, 水谷修紀
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] 2歳時に急性巨核芽球性白血病を発症後、6年後B前駆細胞型急性リンパ性白血病を発症したダウン症女児例2010

    • Author(s)
      遠藤明史, 大川哲平, 小野敏明, 磯田健志, 富澤大輔, 高木正稔, 長澤正之, 森尾友宏, 水谷修紀, 梶原道子
    • Organizer
      第52回日本小児血液学会・第26回日本小児がん学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] ATM regulates adiopocyte differentiation2010

    • Author(s)
      Masatoshi Takagi
    • Organizer
      ATW2010
    • Place of Presentation
      Los Angels(米国)
    • Year and Date
      2010-04-11
    • Data Source
      KAKENHI-PROJECT-22591121
  • [Presentation] DNA Double-Strand Break Formation Induced by Replication Arrest Depend On Artemis.2009

    • Author(s)
      Takagi M, Mizutani S, et al.
    • Organizer
      51th American Society of Hematology Annual meeting 2009.
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-20390302
  • [Presentation] ATMによる腫瘍化制御

    • Author(s)
      高木正稔
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島・鹿児島)
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-25461580
  • 1.  MIZUTANI Shuuki (60126175)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 47 results
  • 2.  Moritake Hiroshi (40336300)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  Urayama Kevin (60726850)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  Isoda Takeshi (80815225)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 5.  SUGIMOTO Koichi (50281358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SUZUKI Hiroshi (00587793)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  FUJIMURA Tsutomu (70245778)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  PIAO Jinhua (70567750)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 9.  SUGIMOTO Masataka (50426491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MOROSHITA Kazuhiro (80260321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KOGA Yuki (60398071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  WATANABE Hiroyoshi (50423413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TSUJI Shoji (70150612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MORISHITA Shinichi (90292854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Aoki Yuki (90706839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  Yanagimachi Masakatsu (00608911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  Goyama Susumu (80431849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  相田 典子 (20586292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  竹内 正宣 (60515477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  後藤 裕明 (90347295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  真部 淳 (20292849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  清河 信敬 (60195401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  重水 大智 (70617464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  森尾 友宏 (30239628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 25.  HOSHINO Akihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  IMAI Kohsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  金兼 弘和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  稲次 基希
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  滝田 順子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  加藤 俊介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  辻本 信一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  谷内 一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  篠原 彰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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