SUGIMOTO Koichi 杉本耕一

… Alternative Names

SUGIMOTO Ko-ichi 杉本耕一

杉本耕一スギモトコウイチ

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Researcher Number	50281358
Other IDs
Affiliation (based on the past Project Information) *help	2009 – 2012: Juntendo University, 医学部, 准教授 2005: Juntendo Univ, Dept of Hematology, Associate Prof, 医学部, 助教授 2002 – 2004: 順天堂大学, 医学部, 講師 2000: 順天堂大学, 医学部, 講師 1999: 順天堂大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / Hematology / Biological Sciences Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine
Keywords	Principal Investigator アポトーシス / EBウイルス / EGFP-EBV / ASK1 / 抗癌剤 / ネクローシス / EGFP / ASK-1 / Nbs1 / Cds1 … More / G2停止 / S期遅延 / ATM / L-asparaginase / NK細胞リンパ腫 / eIF4E / グルタミン / TCAサイクル / NK細胞腫瘍 / alpha-ケトグルタル酸 / 癌細胞代謝 / 炭素骨格分子 / 翻訳開始因子群 / MYC / MCPIP1 / Dicer / マイクロRNA / リンパ腫 / LPS / NK細胞 / 潜伏感染 / G2 / M期停止 / latency I型 / 遺伝子不安定性 / 抗癌剤への耐性 / GFP蛋白質 / 多核細胞 / cdc2 / cdc25C / actin / α-tubulin / NK cell / Latent infection / G2 arrest / Latency type I / Genomic instability / Resistance to chemotherapy … More Except Principal Investigator GFP / 再生医療 / 骨髄間質細胞 / 臍帯血 / PPAR-gamma / 平滑筋細胞 / 分化 / 平滑筋特異的タンパク / smooth muscle / differentiation / regeneration / bone marrow / hematopoietic stem cell / marker gene / 血管平滑筋 / 幹細胞 / 平滑筋前駆細胞 / 平滑筋細胞の発生と分化 / プロモーター / Growth Factor / vascular smooth muscle cell / bone marrow stromal cell / stem cell / progenitor cell / metabolic syndrome / atherosclerosis / neointimal hyperplasia Less

マイクロRNA成熟阻害分子MCPIP1とEBウイルス感染によるリンパ腫発症Principal Investigator
- Principal Investigator
  
  杉本耕一
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Analysis of the mechanism of L-asparaginase to suppress the highly expressed eIF4E in NK-cell lymphomaPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Isolation of bone marrow stromal cell-derived smooth muscle cells by a human SM22α promoter. -Potent Inhibitory Effect of Pioglitazone on Bone Marrow-Derived Smooth Muscle Progenitor Cells-
- Principal Investigator
  
  KATOH Youichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Isolation of bone marrow stromal cell-derived smooth muscle cells by a human SM22alpha promoter: in vitro differentiation of putative smooth muscle progenitor cells of bone marrow
- Principal Investigator
  
  KATOH Youichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Juntendo University
Changes of cell cycle distribution and nuclear structure in NK cells by EBV infectionPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Koichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
抗癌剤によるSおよびG2期での細胞周期停止の検討Principal Investigator
- Principal Investigator
  
  杉本耕一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
抗癌剤の作用におけるASK1の関与Principal Investigator
- Principal Investigator
  
  杉本耕一
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University

All 2012 2011 2010 2009 2004

All Journal Article Presentation

[Journal Article] Expression of Epstein-Barr virus-encoded proteins in extranodal T/NK cell lymphoma, nasal type(ENKL): differences in biological and clinical behaviors of LMP1-positive and negative ENKL2012
- Author(s)
  Kanemitsu N, Isobe Y, Masuda A, Momose S, Higashi M, Tamaru J, Sugimoto K, Komatsu N
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18 Pages: 2164-2172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Bortezomib induces apoptosis in T lymphoma cells and natural killer lymphoma cells independent of epstein-barr virus infection2011
- Author(s)
  Iwata S, Yano S, Ito Y, Ushijima Y, Gotoh K, Kawada JI, Fujiwara S, Sugimoto K, Isobe Y, Nishiyama Y, Kimura H
- Journal Title
  
  Int J Cancer
  
  Volume: 129 Pages: 2263-2273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Usefulness of Systemic CT Scanning in the Detection of Malignant Lymphadenopathy2011
- Author(s)
  Ichikawa K, Sugimoto K, Isobe Y, Kuwatsuru R, Sasaki M, Horiguchi I, Komatsu N
- Journal Title
  
  Medicine
  
  Volume: 90 Pages: 396-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] MCPIP1 ribonuclease antagonizes Dicer and terminates microRNA biogenesis through precursor microRNA degradation2011
- Author(s)
  Suzuki HI, Arase M, Matsuyama H, Choi YL, Mano H, Sugimoto K, Miyazono K
- Journal Title
  
  Mol Cell
  
  Volume: 44 Pages: 424-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Oncogenic NPM-ALK/miR-135b axis mediates Th17 skewing in anaplastic large cell lymphoma2011
- Author(s)
  Matsuyama H, Suzuki HI, Nishimori H, Noguchi M, Yao T, Komatsu N, Mano H, Sugimoto K, Miyazono K
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 6881-6892
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Frequent STAT3 activation is associated with Mcl-1 expression in nasal NK-cell lymphoma2010
- Author(s)
  Tsutsui M, Yasuda H, Suto H, Imai H, Isobe Y, Sasaki M, Kojima Y, Oshimi K, Sugimoto K
- Journal Title
  
  Int J Lab Hematol
  
  Volume: 32 Pages: 419-426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Suppression of eIF4E expression by L-asparaginase2010
- Author(s)
  Suto H, Yasuda H, Isobe Y, Sasaki M, Imai H, Tsutsui M, Oshimi K, Komatsu N, Sugimoto K
- Journal Title
  
  Acta Haematol-Basel
  
  Volume: 123 Pages: 215-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] TGF signaling activates autophagy in human cancer cells2009
- Author(s)
  Kiyono K, Suzuki HI, Morishita Y, Matsuyama H, Komuro A, Kano MR, Sugimoto K, Miyazono K
- Journal Title
  
  Cancer Res
  
  Volume: 69 Pages: 8844-8852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Modulation of microRNA processing by p532009
- Author(s)
  Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, Miyazono K
- Journal Title
  
  Nature
  
  Volume: 460 Pages: 529-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591222
[Journal Article] Epstein-Barr virus infection of human natural killer cell lines and peripheral blood natural killer cells.2004
- Author(s)
  Isobe Y, Sugimoto K, et al.
- Journal Title
  
  Cancer Research 64
  
  Pages: 2167-2174
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570997
[Journal Article] Epstein-Barr virus infection of human natural killer cell lines and peripheral blood natural killer cells.2004
- Author(s)
  Isobe Y, Sugimoto K, Yang L, Tamayose K, Egashira M, Kaneko T, Takada K, Oshimi K
- Journal Title
  
  Cancer Res 64
  
  Pages: 2167-2174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570997
[Presentation] L-アスパラギナーゼのリンパ腫への殺傷効果はglutaminolysisの抑制を介する2011
- Author(s)
  杉本耕一
- Organizer
  日本血液学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] L-アスパラギナーゼのリンパ系腫瘍への殺傷効果はglutaminolysisの抑制を介する2011
- Author(s)
  杉本耕一、鈴木洋、藤村務、大野麻美、磯部泰司、佐々木純、森健、宮園浩平、小松則夫
- Organizer
  臨床血液
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] L-asparaginase reduces several components of translational machinery eIF4F2010
- Author(s)
  Nakamura H, Sugimoto K, Yasuda H, Isobe Y, Sasaki M, Komatsu N
- Organizer
  臨床血液
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] Metformin inhibits lymphoid tumor cell growth through the suppression of translational machinery eIF4F2010
- Author(s)
  Sugimoto K, Isobe Y, Sasaki M, Nakamura H, Komatsu N
- Organizer
  臨床血液
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] Metforminは翻訳開始装置を抑制してリンパ系腫瘍の増殖を抑える2010
- Author(s)
  杉本耕一
- Organizer
  日本血液学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] The p53 world, a wide variety of physiological functions : from signal network to pathogenesis of diseases Dynamics of microRNA biogenesis : crosstalk between p53 network and microRNA processing pathway2010
- Author(s)
  鈴木洋、山形薫、杉本耕一、岩本隆司、加藤茂明、宮園浩平
- Organizer
  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集83回・33回
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] L-asparaginaseのeIF4E抑制とその抗腫瘍効果2009
- Author(s)
  簾藤紘子、佐々木純、磯部泰司、安田肇、今井英則、筒井深雪、押味和夫、杉本耕一
- Organizer
  臨床血液
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] eIF4E抑制を介した L-asparaginase による doxorubicin の殺細胞効果の増強2009
- Author(s)
  杉本耕一
- Organizer
  日本血液学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] p53によるmicroRNAプロセッシングの制御(Modulation of microRNA processing by p53)2009
- Author(s)
  鈴木洋、山形薫、杉本耕一、岩本隆司、加藤茂明、宮園浩平
- Organizer
  日本癌学会総会記事68回
- Data Source
  KAKENHI-PROJECT-21591222
[Presentation] eIF4E抑制を介したL-asparaginaseによるdoxorubicinの殺細胞効果の増強2009
- Author(s)
  杉本耕一、佐々木純、簾藤紘子、磯部泰司、稲垣直子
- Organizer
  臨床血液
- Data Source
  KAKENHI-PROJECT-21591222

1. KATOH Youichi (00231259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. YUHARA Chiharu (90281360)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SUZUKI Hiroshi (00587793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. FUJIMURA Tsutomu (70245778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. TAKAGI Masatoshi (10406267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SUGIMOTO Koichi 杉本 耕一

SUGIMOTO Ko-ichi 杉本 耕一

杉本 耕一 スギモト コウイチ

Research Projects

Research Products

Co-Researchers

マイクロRNA成熟阻害分子MCPIP1とEBウイルス感染によるリンパ腫発症Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism of L-asparaginase to suppress the highly expressed eIF4E in NK-cell lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of bone marrow stromal cell-derived smooth muscle cells by a human SM22α promoter. -Potent Inhibitory Effect of Pioglitazone on Bone Marrow-Derived Smooth Muscle Progenitor Cells-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of bone marrow stromal cell-derived smooth muscle cells by a human SM22alpha promoter: in vitro differentiation of putative smooth muscle progenitor cells of bone marrow

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Changes of cell cycle distribution and nuclear structure in NK cells by EBV infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗癌剤によるSおよびG2期での細胞周期停止の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

抗癌剤の作用におけるASK1の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of Epstein-Barr virus-encoded proteins in extranodal T/NK cell lymphoma, nasal type(ENKL): differences in biological and clinical behaviors of LMP1-positive and negative ENKL2012

Author(s)

Journal Title

Data Source

[Journal Article] Bortezomib induces apoptosis in T lymphoma cells and natural killer lymphoma cells independent of epstein-barr virus infection2011

Author(s)

Journal Title

Data Source

[Journal Article] Usefulness of Systemic CT Scanning in the Detection of Malignant Lymphadenopathy2011

Author(s)

Journal Title

Data Source

[Journal Article] MCPIP1 ribonuclease antagonizes Dicer and terminates microRNA biogenesis through precursor microRNA degradation2011

Author(s)

Journal Title

Data Source

[Journal Article] Oncogenic NPM-ALK/miR-135b axis mediates Th17 skewing in anaplastic large cell lymphoma2011

Author(s)

Journal Title

Data Source

[Journal Article] Frequent STAT3 activation is associated with Mcl-1 expression in nasal NK-cell lymphoma2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of eIF4E expression by L-asparaginase2010

Author(s)

Journal Title

Data Source

[Journal Article] TGF signaling activates autophagy in human cancer cells2009

Author(s)

Journal Title

Data Source

SUGIMOTO Koichi 杉本耕一

SUGIMOTO Ko-ichi 杉本耕一

杉本耕一スギモトコウイチ