Isoda Takeshi 磯田健志

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ISODA TAKESHI 磯田健志

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Researcher Number	80815225
Other IDs
Affiliation (Current)	2023: 東京医科歯科大学, 大学院医歯学総合研究科, 講師
Affiliation (based on the past Project Information) *help	2021 – 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2018 – 2021: 東京医科歯科大学, 医学部附属病院, 助教 2020: 東京医科歯科大学, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 非コードRNA / 免疫不全症 / エピジェネティクス / ThymoD / メチル化 / エンハンサー活性制御 / 急性リンパ性白血病 / 非ホジキンリンパ腫 / T細胞分化 / 運命決定 … More / エンハンサー / R-loop / 白血病 / 転写 / ゲノムの３次元構造 … More Except Principal Investigator 非コードRNA / T細胞分化 / 胸腺 / エピジェネティクス / 転写因子 / 白血病 / 転写制御 / がん化 Less

制御領域の変異同定と非コードRNA転写・スーパーエンハンサー活性化機構の解明Principal Investigator
- Principal Investigator
  
  磯田健志
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokyo Medical and Dental University
Roles of a non-coding RNA that regulates normal and neoplastic T cell development
- Principal Investigator
  
  Ikawa Tomokatsu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Tokyo University of Science
Investigation for control of enhancer activity by non-coding RNA transcription and mechanism of developing primary immunodeficiency and oncogenesis under the disrupted non-coding transcription.Principal Investigator
- Principal Investigator
  
  ISODA TAKESHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokyo Medical and Dental University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Identification of Germline Non-coding Deletions in XIAP Gene Causing XIAP Deficiency Reveals a Key Promoter Sequence.2022
- Author(s)
  Sbihi Zineb、Tanita Kay、Bachelet Camille、Bole Christine、Jabot-Hanin Fabienne、…Isoda Takeshi（24人中20番目）、…、Kanegane Hirokazu、Latour Sylvain
- Journal Title
  
  J Clin Immunol.
  
  Volume: 42 Pages: 559-571
- DOI
  10.1007/s10875-021-01188-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02878, KAKENHI-PROJECT-20J10721, KAKENHI-PROJECT-20K08152
[Journal Article] Novel variants for Glanzmann thrombasthenia manifesting with purpura at birth2022
- Author(s)
  Eguchi Shiori、Isoda Takeshi、Yamaguchi Asuka、Takagi Masatoshi
- Journal Title
  
  Pediatrics International
  
  Volume: 64
- DOI
  10.1111/ped.15149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02878
[Journal Article] Successful ruxolitinib administration for a patient with steroid‐refractory idiopathic pneumonia syndrome following hematopoietic stem cell transplantation: A case report and literature review2021
- Author(s)
  Tomomasa Dan、Isoda Takeshi、Mitsuiki Noriko、Yamashita Motoi、Morishita Aoi、Tomoda Takahiro、Okano Tsubasa、Endo Akifumi、Kamiya Takahiro、Yanagimachi Masakatsu、Imai Kohsuke、Kanegane Hirokazu、Takagi Masatoshi、Morio Tomohiro
- Journal Title
  
  Clinical Case Reports
  
  Volume: 9 Pages: 1-9
- DOI
  10.1002/ccr3.5242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02878, KAKENHI-PROJECT-20K16437
[Journal Article] Cytomegalovirus Laryngitis in Primary Combined Immunodeficiency Diseases2021
- Author(s)
  Inoue Maiko、Isoda Takeshi、Yamashita Motoi、Tomoda Takahiro、Inoue Kento、Okano Tsubasa、Ohkawa Teppei、Endo Akifumi、Mitsuiki Noriko、Kamiya Takahiro、Yanagimachi Masakatsu、Yamamoto Kouhei、Inaba Yuichiro、Sasaki Toru、Takagi Masatoshi、Kanegane Hirokazu、Imai Kohsuke、Morio Tomohiro
- Journal Title
  
  J Clin Immunol.
  
  Volume: 41 Pages: 243-247
- DOI
  10.1007/s10875-020-00873-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17460, KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-18K15661
[Journal Article] Upon Microbial Challenge, Human Neutrophils Undergo Rapid Changes in Nuclear Architecture and Chromatin Folding to Orchestrate an Immediate Inflammatory Gene Program2020
- Author(s)
  Matthew Denholtz, Yina Zhu, Zhaoren He, Hanbin Lu, Takeshi Isoda, Simon Dohrmann, Victor Nizet, Cornelis Murre
- Journal Title
  
  Genes and Development
  
  Volume: 34 Pages: 149-165
- DOI
  10.1101/gad.333708.119
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15661
[Journal Article] Noncoding RNA transcription at enhancers and genome folding in cancer2019
- Author(s)
  Takeshi Isoda, Tomohiro Morio, Masatoshi Takagi
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 2328-2336
- DOI
  10.1111/cas.14107
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] ロングリードシークエンサーを用いた先天性免疫不全症・白血病発症機構の解明2021
- Author(s)
  磯田健志
- Organizer
  令和３年度川野小児医学奨学財団助成研究成果発表会
- Data Source
  KAKENHI-PROJECT-21H02878
[Presentation] 非コードRNA転写異常を背景とした免疫不全、発がんの病態探索2020
- Author(s)
  磯田健志、森尾友宏
- Organizer
  第48回日本臨床免疫学会総会　シンポジウム3　病態探索に挑む
- Invited
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] 非コードRNA転写による核内局在転換はT細胞への系列決定を誘導しT細胞系腫瘍の抑制に関与する2020
- Author(s)
  Isoda T, Nishimura A, Morio T, Takagi M
- Organizer
  第 62 回日本小児血液・がん学会学術集会　シンポジウム 4 血液基礎、核ダイナミクスから non-mRNA による細胞制御
- Invited
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] BTK転写調節の異常によるX連鎖無ガンマグロブリン血症の3家系2019
- Author(s)
  石橋佑脩、岡野翼、谷田けい、磯田健志、小林法元、藤原享志、座波清誉、野々山恵章、今井耕輔、森尾友宏、金兼弘和
- Organizer
  第2回日本免疫不全・自己炎症学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] Non-Coding RNA ThymoD Transcription Modulates Nuclear Architecture to Orchestrate T-Cell Fate and Block T-Cell Malignancies2018
- Author(s)
  T.Isoda, A.Nishimura,S.Miyamoto,T.Morio,M.Takagi, C. Murre
- Organizer
  50th SIOP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] Non-coding RNA ThymoD transcription modulates nuclear architecture to specify T-cell fate and inhibits T-cell malignancies2018
- Author(s)
  磯田健志
- Organizer
  第47回日本免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] 非コードRNA転写によるエンハンサー、プロモーターの相互作用の誘導が、T細胞の運命決定を指揮する2018
- Author(s)
  磯田健志
- Organizer
  第28回京都T細胞カンファレンス学術集会
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] Non-coding RNA transcription modulates nuclear architecture to specify T-cell fate and blocks T-cell malignancies2018
- Author(s)
  磯田健志、高木正稔
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15661
[Presentation] ThymoD modulates nuclear architecture to specify T-cell fate and blocks T-cell malignancies2018
- Author(s)
  Takeshi Isoda, Akira Nishimura, Satoshi Miyamoto, Tomohiro Morio, Masatoshi Takagi, Cornelis Murre
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15661

1. Ikawa Tomokatsu (60450392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 高野淳一朗 (00852162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 高木正稔 (10406267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 森尾友宏 (30239628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. IMAI Kohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Isoda Takeshi 磯田 健志

ISODA TAKESHI 磯田 健志

Research Projects

Research Products

Co-Researchers

制御領域の変異同定と非コードRNA転写・スーパーエンハンサー活性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of a non-coding RNA that regulates normal and neoplastic T cell development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation for control of enhancer activity by non-coding RNA transcription and mechanism of developing primary immunodeficiency and oncogenesis under the disrupted non-coding transcription.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Identification of Germline Non-coding Deletions in XIAP Gene Causing XIAP Deficiency Reveals a Key Promoter Sequence.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel variants for Glanzmann thrombasthenia manifesting with purpura at birth2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful ruxolitinib administration for a patient with steroid‐refractory idiopathic pneumonia syndrome following hematopoietic stem cell transplantation: A case report and literature review2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytomegalovirus Laryngitis in Primary Combined Immunodeficiency Diseases2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upon Microbial Challenge, Human Neutrophils Undergo Rapid Changes in Nuclear Architecture and Chromatin Folding to Orchestrate an Immediate Inflammatory Gene Program2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Noncoding RNA transcription at enhancers and genome folding in cancer2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] ロングリードシークエンサーを用いた先天性免疫不全症・白血病発症機構の解明2021

Author(s)

Organizer

Data Source

[Presentation] 非コードRNA転写異常を背景とした免疫不全、発がんの病態探索2020

Author(s)

Organizer

Data Source

[Presentation] 非コードRNA転写による核内局在転換はT細胞への系列決定を誘導しT細胞系腫瘍の抑制に関与する2020

Author(s)

Organizer

Data Source

[Presentation] BTK転写調節の異常によるX連鎖無ガンマグロブリン血症の3家系2019

Author(s)

Organizer

Data Source

[Presentation] Non-Coding RNA ThymoD Transcription Modulates Nuclear Architecture to Orchestrate T-Cell Fate and Block T-Cell Malignancies2018

Author(s)

Organizer

Data Source

[Presentation] Non-coding RNA ThymoD transcription modulates nuclear architecture to specify T-cell fate and inhibits T-cell malignancies2018

Author(s)

Organizer

Data Source

[Presentation] 非コードRNA転写によるエンハンサー、プロモーターの相互作用の誘導が、T細胞の運命決定を指揮する2018

Author(s)

Organizer

Isoda Takeshi 磯田健志

ISODA TAKESHI 磯田健志