Tomita Shuhei 冨田修平

… Alternative Names

Researcher Number	00263898
Other IDs
Affiliation (Current)	2022: 大阪公立大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2020: 大阪市立大学, 大学院医学研究科, 教授 2012 – 2016: 鳥取大学, 医学部, 教授 2008 – 2011: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 准教授 2007: The University of Tokushima, ゲノム機能研究センター, 准教授 2003 – 2006: 徳島大学, ゲノム機能研究センター, 助教授 … More
Review Section/Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry / General pharmacology / General medical chemistry / Immunology / Basic Section 47040:Pharmacology-related Except Principal Investigator General medical chemistry / General pharmacology / Biological Sciences / Emergency medicine / Anesthesiology / Applied pharmacology / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 低酸素 / 転写因子 / HIF / 血管内皮細胞 / 低酸素応答 / シトクロムP-450 / レチノイン酸合成酵素 / T細胞 / Hypoxia Inducible Factor / 肺高血圧症 … More Except Principal Investigator 低酸素 / シトクロムP-450 / レチノイン酸合成酵素 / モノオキシゲナーゼ / レチノイド / ヘム酵素 / レチナ-ル酸化酵素 / フラビン酵素 / 脱水素酵素 / 腎臓 / 亜硝酸 / 亜硝酸塩 / 一酸化窒素 / 代謝 / 腎保護作用 / 耐糖能 / 硝酸塩 / 糸球体内皮細胞 / ラット / AMPK / STZ / MIN6細胞 / 硝酸 / 経口 / 腎糸球体内皮細胞 / マウス / OGTT / Tリンパ球 / 細胞分化 / レパトア選択 / 胸腺 / ケモカイン / 細胞移動 / 免疫寛容 / メダカ / 免疫学 / 発生・分化 / ゲノム / 細胞・組織 / 移植・再生医療 / 器官構築 / CCR7 / 自己寛容 / CCL21 / CCL25 / T lymphocytes / Cellular differentiation / Repertoire formation / Thymus / Chemokines / Cellular movement / Immunological tolerance / medaka / 低酸素症 / 100％酸素蘇生 / 空気蘇生 / 蘇生ガイドライン / TNF α / IL-1β / caspase-3 / BDNF / 脳神経障害 / 脳エリスロポイチン / 脳由来神経栄養因子 / 脳神経障害発症機序 / 低酸素・再酸素化 / 100％酸素 / 炎症性サイトカイン / 臓器障害 / 低酸素再酸素化 / 肝障害 / 低酸素蘇生 / アポトーシス / 腎障害 / 心肺蘇生 / 脳障害 / 成人 / 腎線維化 / 低酸素誘導因子 / HIF-PHD阻害薬 / 血管新生 / PAI-1 / CTGF / 血管内皮増殖因子 / 線維化 / UUOモデル / HIF / PHD阻害剤 / CKD / 喫煙 / 早期血管障害 / 血管内皮機能 / 遺伝子検査学 / 老化 Less

PHD阻害薬による自然免疫活性化に基づく抗腫瘍メカニズムの解明と治療標的の探索Principal Investigator
- Principal Investigator
  
  冨田修平
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka City University
喫煙による早期血管障害におけるmicroRNAの関与と機序
- Principal Investigator
  
  竹本恭彦
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Osaka City University
Basic research of cancer therapy by improving anticancer drug sensitivity through tumor vascular remodelingPrincipal Investigator
- Principal Investigator
  
  Tomita Shuhei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka City University
Angiogenesis in renal fibrosis
- Principal Investigator
  
  Miura Katsuyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka City University
Mechanism of organ damage caused by 100% oxygen reoxygenation after adult hypoxia and establishment of its treatment strategy
- Principal Investigator
  
  Ueki Masaaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Kobe University
Tumor blood vessel normalization by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumor mouse modelPrincipal Investigator
- Principal Investigator
  
  Tomita Shuhei
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka City University
  Tottori University
Reoxygenation with 100% oxygen following hypoxia in mice causes apoptosis
- Principal Investigator
  
  NISHIYAMA TAKASHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Kobe University
Mechanism of hypoxia-induced transformation in endothelial cellsPrincipal Investigator
- Principal Investigator
  
  TOMITA Shuhei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tottori University
The renal protective effects of nitrite salts in diabetic nephropathy model rats.
- Principal Investigator
  
  TSUCHIYA Koichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokushima
Mechanisms of hypoxia-induced transformation in endothelial cellsPrincipal Investigator
- Principal Investigator
  
  TOMITA Shuhei
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
CharaGterization of the evoked inflammation via hypoxic response in endothelial cellsPrincipal Investigator
- Principal Investigator
  
  TOMITA Tomita
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
The roles of HIF-1α in T cell-dependent immune responsesPrincipal Investigator
- Principal Investigator
  
  TOMITA Shuhei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima
神経系細胞系譜的HIF-1α遺伝子欠失マウスの作製と解析Principal Investigator
- Principal Investigator
  
  冨田修平
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Thymocyte dynamics and hymus organogenesis
- Principal Investigator
  
  TAKAHAMA Yousuke
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
T細胞増殖応答におけるARNTの生理機能Principal Investigator
- Principal Investigator
  
  冨田修平
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The Institute of Physical and Chemical Research
  香川医科大学
Characterization of retinoic acid synthasesPrincipal Investigator
- Principal Investigator
  
  TOMITA Shuhei, 市川佳幸
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kagawa Medical University
レチノイン酸合成酵素の多様性とその特性並びに生理的役割
- Principal Investigator
  
  市川佳幸
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  香川医科大学
ミクロソーム型レチノイン酸合成酵素(シトクロムP-450_<RA>)の酵素化学的特性Principal Investigator
- Principal Investigator
  
  富田修平
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  香川医科大学

[Book] エース薬理学2020
- Author(s)
  金井好克、安西尚彦、安藤　仁、浅井　聰、冨田修平
- Total Pages
  303
- Publisher
  南山堂
- ISBN
  9784525140717
- Data Source
  KAKENHI-PROJECT-20K07072
[Book] 尿酸と血糖「第5回忙しい人のための抄読会」2016
- Author(s)
  松永慎司，冨田修平
- Total Pages
  4
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15K15054
[Book] 炎症と免疫「低酸素と生活習慣病」2016
- Author(s)
  冨田修平，木平孝高，玉置俊晃
- Total Pages
  7
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15K15054
[Book] 医学のあゆみ（別冊）レドックスUPDATE「血管リモデリングにおける低酸素応答性転写因子の役割」2015
- Author(s)
  冨田修平, 松永慎司
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-15K15054
[Book] アンジオテンシンII刺激による細胞内遊離鉄を介した酸化ストレス増強機構2010
- Author(s)
  田島壮一郎, 土屋浩一郎, 濱本磨以, 久住祥子, 堀ノ内裕也, 八木祐子, 櫻田巧, 石澤啓介, 池田康将, 木平孝高, 冨田修平, 玉置俊晃
- Publisher
  腎とフリーラジカル
- Data Source
  KAKENHI-PROJECT-21590335
[Book] 医学のあゆみ, Vascular Biology Update『中枢神経系と血管形成』2008
- Author(s)
  冨田修平
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19590281
[Book] ハイドロエチジウム蛍光分析法による細胞内スーパーオキシド検出法の評価2008
- Author(s)
  大西秀樹, 土屋浩一郎, 田島壮一郎, 堀ノ内裕也, 山口邦久, 石澤啓介, 冨田修平, 玉置俊晃
- Publisher
  腎とフリーラジカル(9)
- Data Source
  KAKENHI-PROJECT-19590281
[Book] オルメサルタンはPDGFによるメサンギウム細胞遊走を抑制する2008
- Author(s)
  石澤啓介, 三木恵里加, 石澤有紀, 大西秀樹, Narantungalag Dorjsuren, 元林有紀, 山口邦久, 土屋浩一郎, 冨田修平, 玉置俊晃
- Publisher
  腎とフリーラジカル(9)
- Data Source
  KAKENHI-PROJECT-19590281
[Book] 中枢神経系と血管形成(Vascular Biology Update)2007
- Author(s)
  冨田修平
- Publisher
  医学のあゆみ(223)
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] HIF-1α controls palatal wound healing by regulating macrophage motility via S1P/S1P1 signaling axis.2021
- Author(s)
  Hutami Islamy Rahma、Izawa Takashi、Khurel‐Ochir Tsendsuren、Sakamaki Takuma、Iwasa Akihiko、Tomita Shuhei、Tanaka Eiji
- Journal Title
  
  Oral Diseases
  
  Volume: -
- DOI
  10.1111/odi.13856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07072, KAKENHI-PROJECT-18KK0464, KAKENHI-PROJECT-18H03011
[Journal Article] Inhibitory effects of iron depletion plus eribulin on the breast cancer microenvironment.2020
- Author(s)
  Goto Wataru、Kashiwagi Shinichiro、Asano Yuka、Takada Koji、Morisaki Tamami、Takahashi Katsuyuki、Fujita Hisakazu、Shibutani Masatsune、Amano Ryosuke、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Pages: 1215-1215
- DOI
  10.1186/s12885-020-07673-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-20K08938, KAKENHI-PROJECT-19K18038, KAKENHI-PROJECT-19K18046
[Journal Article] Clinical significance of tumor-infiltrating lymphocytes (TILs) in endocrine therapy for stage IV breast cancer.2020
- Author(s)
  Asano Yuka、Kashiwagi Shinichiro、Goto Wataru、Takada Koji、Takahashi Katsuyuki、Shibutani Masatsune、Amano Ryosuke、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 13 Pages: 195202-195202
- DOI
  10.3892/mco.2020.2063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-20K08938, KAKENHI-PROJECT-19K18038, KAKENHI-PROJECT-19K18046
[Journal Article] The effects of eribulin on breast cancer microenvironment identified using eribulin-resistant breast cancer cell lines2020
- Author(s)
  Goto W, Kashiwagi S, Asano Y, Takada K, Takahashi K, Fujita H, Takashima T, Shibutani M, Amano R, Tomita S, Hirakawa K, Ohira M.
- Journal Title
  
  Anticancer research
  
  Volume: 39 Pages: 40314041-40314041
- DOI
  10.21873/anticanres.13559
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18038, KAKENHI-PROJECT-19K18046, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17K08602
[Journal Article] Soluble urokinase-type plasminogen activator receptor represents exercise tolerance and predicts adverse cardiac events in patients with heart failure2020
- Author(s)
  Ishikawa H, Izumiya Y, Shibata A, Ichikawa Y, Yamaguchi T, Yamaguchi Y, Kitada R, Iwata S, Ehara S, Tomita S, Hanatani A, Yoshiyama M.
- Journal Title
  
  Heart and Vessels
  
  Volume: 35 Pages: 681-688
- DOI
  10.1007/s00380-019-01538-3
- NAID
  120006936889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08493, KAKENHI-PROJECT-19K16651, KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-17K08602
[Journal Article] Effects of orally active hypoxia inducible factor alpha prolyl hydroxylase inhibitor, FG4592 on renal fibrogenic potential in mouse unilateral ureteral obstruction model.2020
- Author(s)
  Kabei Kazuya、Tateishi Yu、Shiota Masayuki、Osada-Oka Mayuko、Nishide Shunji、Uchida Junji、Nakatani Tatsuya、Matsunaga Shinji、Yamaguchi Takehiro、Tomita Shuhei、Miura Katsuyuki
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 142 Pages: 93-100
- DOI
  10.1016/j.jphs.2019.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-19K16651, KAKENHI-PROJECT-17K08836, KAKENHI-PROJECT-17K08958, KAKENHI-PROJECT-20K07072, KAKENHI-PROJECT-17K08602
[Journal Article] The effect of PHD inhibitor on tumor microenvironment and tumor immune response2020
- Author(s)
  Matsunaga S, Tomita S.
- Journal Title
  
  Folia Pharmacol. Jpn.
  
  Volume: 155 Issue: 1 Pages: 35-39
- DOI
  10.1254/fpj.19119
- NAID
  130007778893
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17K08602
[Journal Article] Factors predictive of invasive ductal carcinoma in cases preoperatively diagnosed as ductal carcinoma in situ.2020
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Asano Yuka、Goto Wataru、Morisaki Tamami、Takahashi Katsuyuki、Fujita Hisakazu、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Pages: 513-513
- DOI
  10.1186/s12885-020-07001-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-20K08938, KAKENHI-PROJECT-19K18038, KAKENHI-PROJECT-19K18067
[Journal Article] Hypoxia?inducible factor?1α regulates Lipin1 differently in pre?adipocytes and mature adipocytes2020
- Author(s)
  Kihira Yoshitaka、Fujimura Yoshino、Tomita Shuhei、Tamaki Toshiaki、Sato Eiji
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 22 Pages: 559-565
- DOI
  10.3892/mmr.2020.11076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-20K07072
[Journal Article] Yohimbine ameliorates lipopolysaccharide-induced acute kidney injury in rats.2020
- Author(s)
  Shimokawa Takaomi、Yoneda Kozo、Yamagata Masayo、Hayashi Kohei、Tomita Shuhei
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 871 Pages: 172917-172917
- DOI
  10.1016/j.ejphar.2020.172917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-20K07072, KAKENHI-PROJECT-17K08602
[Journal Article] Significance of the age-related quality of life for endocrine therapy in patients with stage IV breast cancer in Japan.2020
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Asano Yuka、Goto Wataru、Morisaki Tamami、Takahashi Katsuyuki、Shibutani Masatsune、Amano Ryosuke、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Oncology Letters
  
  Volume: 20 Pages: 1-1
- DOI
  10.3892/ol.2020.12041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07943, KAKENHI-PROJECT-19K18067
[Journal Article] Prolyl-hydroxylase inhibitors reconstitute tumor blood vessels in mice.2020
- Author(s)
  Nishide Shunji、Uchida Junji、Matsunaga Shinji、Tokudome Kentaro、Yamaguchi Takehiro、Kabei Kazuya、Moriya Taiki、Miura Katsuyuki、Nakatani Tatsuya、Tomita Shuhei
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 143 Pages: 122-126
- DOI
  10.1016/j.jphs.2020.02.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14598, KAKENHI-PROJECT-19K16651, KAKENHI-PROJECT-19K18594, KAKENHI-PROJECT-17K08958, KAKENHI-PROJECT-20K07072, KAKENHI-PROJECT-17K08602
[Journal Article] A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.2019
- Author(s)
  Yamaguchi Takehiro、Watanabe Ayano、Tanaka Masako、Shiota Masayuki、Osada-Oka Mayuko、Sano Soichi、Yoshiyama Minoru、Miura Katsuyuki、Kitajima Shojiro、Matsunaga Shinji、Tomita Shuhei、Iwao Hiroshi、Izumi Yasukatsu
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 139 Pages: 112-119
- DOI
  10.1016/j.jphs.2018.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K08958, KAKENHI-PROJECT-17K15757, KAKENHI-PROJECT-15K08649
[Journal Article] Clinical Evaluation of Dynamic Monitoring of Neutrophil-to-lymphocyte and Platelet-to-lymphocyte Ratios in Primary Endocrine Therapy for Advanced Breast Cancer.2019
- Author(s)
  Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Shibutani M, Amano R, Takashima T, Tomita S, Hirakawa K, Ohira M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Pages: 55815588-55815588
- DOI
  10.21873/anticanres.13752
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18046, KAKENHI-PROJECT-17K08602
[Journal Article] Verification of the effects of calcium channel blockers on the immune microenvironment of breast cancer.2019
- Author(s)
  Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Fujita H, Takashima T, Tomita S, Hirakawa K, Ohira M.
- Journal Title
  
  BMC Cancer.
  
  Volume: 19 Pages: 615-615
- DOI
  10.1186/s12885-019-5828-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18067, KAKENHI-PROJECT-17K08602
[Journal Article] Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model.2019
- Author(s)
  Nishide Shunji、Matsunaga Shinji、Shiota Masayuki、Yamaguchi Takehiro、Kitajima Shojiro、Maekawa Yoichi、Takeda Norihiko、Tomura Michio、Uchida Junji、Miura Katsuyuki、Nakatani Tatsuya、Tomita Shuhei
- Journal Title
  
  iScience
  
  Volume: 19 Pages: 940-954
- DOI
  10.1016/j.isci.2019.08.033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16651, KAKENHI-PROJECT-19K18594, KAKENHI-PROJECT-17K08958
[Journal Article] Clinical verification of the relationship between smoking and the immune microenvironment of breast cancer.2019
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Asano Yuka、Goto Wataru、Takahashi Katsuyuki、Fujita Hisakazu、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  J Transl Med.
  
  Volume: 17 Pages: 13-13
- DOI
  10.1186/s12967-019-1773-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17H07023, KAKENHI-PROJECT-19K18038, KAKENHI-PROJECT-19K18067
[Journal Article] Prognostic Value of Quality of Life in Endocrine Therapy for Elderly Patients With Breast Cancer: A Retrospective Study.2019
- Author(s)
  Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Shibutani M, Amano R, Takashima T, Tomita S, Hirakawa K, Ohira M
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Pages: 29412950-29412950
- DOI
  10.21873/anticanres.13424
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18046, KAKENHI-PROJECT-17K08602
[Journal Article] Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model.2019
- Author(s)
  Nishide Shunji、Matsunaga Shinji、Shiota Masayuki、Yamaguchi Takehiro、Kitajima Shojiro、Maekawa Yoichi、Takeda Norihiko、Tomura Michio、Uchida Junji、Miura Katsuyuki、Nakatani Tatsuya、Tomita Shuhei
- Journal Title
  
  iScience
  
  Volume: 21 Pages: 205-205
- DOI
  10.1016/j.isci.2019.10.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21582, KAKENHI-PROJECT-17K08602
[Journal Article] Clinical Outcomes of Recombinant Human-soluble Thrombomodulin Treatment for Disseminated Intravascular Coagulation in Solid Tumors.2019
- Author(s)
  Kashiwagi S, Asano Y, Takahashi K, Shibutani M, Amano R, Tomita S, Hirakawa K, Ohira M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Pages: 2259-2264
- DOI
  10.21873/anticanres.13342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17K08602
[Journal Article] Improving the safety of high-concentration potassium chloride injection.2019
- Author(s)
  Nakatani K, Nakagami-Yamaguchi E, Shinoda Y, Tomita S, Nakatani T.
- Journal Title
  
  BMJ Open Qual.
  
  Volume: 8
- DOI
  10.1136/bmjoq-2019-000666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08602
[Journal Article] Use of the tumor-infiltrating CD8 to FOXP3 lymphocyte ratio in predicting treatment responses to combination therapy with pertuzumab, trastuzumab, and docetaxel for advanced HER2-positive breast cancer.2018
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Goto Wataru、Asano Yuka、Takahashi Katsuyuki、Takashima Tsutomu、Tomita Shuhei、Ohsawa Masahiko、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 16 Pages: 86-86
- DOI
  10.1186/s12967-018-1460-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559
[Journal Article] Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells.2018
- Author(s)
  Kitajima Shojiro、Lee Kian Leong、Fujioka Masaki、Sun Wendi、You Jia、Chia Grace Sushin、Wanibuchi Hideki、Tomita Shuhei、Araki Marito、Kato Hiroyuki、Poellinger Lorenz
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 19123-19135
- DOI
  10.18632/oncotarget.24919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-18K16743
[Journal Article] Role of hypoxia-inducible factor-1 in the development of renal fibrosis in mouse obstructed kidney: Special references to HIF-1 dependent gene expression of profibrogenic molecules2018
- Author(s)
  Kabei Kazuya、Tateishi Yu、Nozaki Masakazu、Tanaka Masako、Shiota Masayuki、Osada-Oka Mayuko、Nishide Shunji、Uchida Junji、Nakatani Tatsuya、Tomita Shuhei、Miura Katsuyuki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 136 Pages: 31-38
- DOI
  10.1016/j.jphs.2017.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K08958, KAKENHI-PROJECT-17K15757
[Journal Article] Mesenchymal epithelial transition and tumor vascular remodeling in eribulin chemotherapy for breast cancer.2018
- Author(s)
  Kashiwagi S, Asano Y, Goto W, Takada K, Takahashi K, Hatano T, Tanaka S, Takashima T, Tomita S, Motomura H, Ohsawa M, Hirakawa K, Ohira M.
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Pages: 401-410
- DOI
  10.21873/anticanres.12236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559
[Journal Article] Possibility of omitting axillary lymph node dissection by immune microenvironment monitoring in preoperative chemotherapy for breast cancer.2018
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Goto Wataru、Asano Yuka、Takahashi Katsuyuki、Fujita Hisakazu、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 16 Pages: 318-318
- DOI
  10.1186/s12967-018-1692-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559
[Journal Article] Red ginseng extracts attenuate skin inflammation in atopic dermatitis through p70 ribosomal protein S6 kinase activation2018
- Author(s)
  Osada-Oka Mayuko、Hirai Sayaka、Izumi Yasukatsu、Misumi Kazuhiro、Samukawa Keiichi、Tomita Shuhei、Miura Katsuyuki、Minamiyama Yukiko、Iwao Hiroshi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 136 Pages: 9-15
- DOI
  10.1016/j.jphs.2017.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K08958
[Journal Article] Prediction of treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer by analysis of immune checkpoint protein expression2018
- Author(s)
  Asano Y, Kashiwagi S, Goto W, Takada K, Takahashi K, Morisaki T, Fujita H, Takashima T, Tomita S, Ohsawa M, Hirakawa K, Ohira M.
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 16 Pages: 87-87
- DOI
  10.1186/s12967-018-1458-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13225, KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17H07023
[Journal Article] Predictive value of lymphocyte-to-monocyte ratio in the preoperative setting for progression of patients with breast cancer.2018
- Author(s)
  Goto Wataru、Kashiwagi Shinichiro、Asano Yuka、Takada Koji、Takahashi Katsuyuki、Hatano Takaharu、Takashima Tsutomu、Tomita Shuhei、Motomura Hisashi、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Pages: 1137-1137
- DOI
  10.1186/s12885-018-5051-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559
[Journal Article] Mesenchymal-epithelial Transition and Tumor Vascular Remodeling in Eribulin Chemotherapy for Breast Cancer.2018
- Author(s)
  Kashiwagi S, Asano Y, Goto W, Takada K, Takahashi K, Hatano T, Tanaka S, Takashima T, Tomita S, Motomura H, Ohsawa M, Hirakawa K, Ohira M
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Pages: 401-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08602
[Journal Article] Significance of re-biopsy for recurrent breast cancer in the immune tumor microenvironment.2018
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Goto Wataru、Asano Yuka、Takahashi Katsuyuki、Hatano Takaharu、Takashima Tsutomu、Tomita Shuhei、Motomura Hisashi、Ohsawa Masahiko、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  British Journal of Cancer
  
  Volume: 119 Pages: 572-579
- DOI
  10.1038/s41416-018-0197-4
- NAID
  120006548611
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17H07023
[Journal Article] Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer.2018
- Author(s)
  Takada Koji、Kashiwagi Shinichiro、Goto Wataru、Asano Yuka、Takahashi Katsuyuki、Morisaki Tamami、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 144 Pages: 1547-1559
- DOI
  10.1007/s00432-018-2670-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17K13225
[Journal Article] Prediction of the treatment response to neoadjuvant chemotherapy in breast cancer by subtypes using tumor-infiltrating lymphocytes.2018
- Author(s)
  Asano Y, Kashiwagi S, Goto W, Takada K, Takahashi K, Hatano T, Takashima T, Tomita S, Motomura H, Ohsawa M, Hirakawa K, Ohira M.
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Pages: 2311-2321
- DOI
  10.21873/anticanres.12476
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17H07023
[Journal Article] Predictive value of improvement in the immune tumour microenvironment in patients with breast cancer treated with neoadjuvant chemotherapy.2018
- Author(s)
  Goto Wataru、Kashiwagi Shinichiro、Asano Yuka、Takada Koji、Takahashi Katsuyuki、Hatano Takaharu、Takashima Tsutomu、Tomita Shuhei、Motomura Hisashi、Ohsawa Masahiko、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  ESMO Open
  
  Volume: 3
- DOI
  10.1136/esmoopen-2017-000305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17H07023
[Journal Article] Study on the progression types of cancer in patients with breast cancer undergoing eribulin chemotherapy and tumor microenvironment.2018
- Author(s)
  Kashiwagi Shinichiro、Tsujio Gen、Asano Yuka、Goto Wataru、Takada Koji、Takahashi Katsuyuki、Morisaki Tamami、Fujita Hisakazu、Takashima Tsutomu、Tomita Shuhei、Ohsawa Masahiko、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 16 Pages: 54-54
- DOI
  10.1186/s12967-018-1443-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559, KAKENHI-PROJECT-17K13225, KAKENHI-PROJECT-17H07023
[Journal Article] Clinical Significance of the Neutrophil?to?Lymphocyte Ratio in Endocrine Therapy for Stage IV Breast Cancer2018
- Author(s)
  Iimori N, Kashiwagi S, Asano Y, Goto W, Takada K, Takahashi K, Hatano T, Takashima T, Tomita S, Motomura H, Hirakawa K, Ohira M.
- Journal Title
  
  In Vivo
  
  Volume: 32
- DOI
  10.21873/invivo.11292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08602
[Journal Article] Significance of intrinsic breast cancer subtypes on the long-term prognosis after neoadjuvant chemotherapy.2018
- Author(s)
  Goto Wataru、Kashiwagi Shinichiro、Takada Koji、Asano Yuka、Takahashi Katsuyuki、Fujita Hisakazu、Takashima Tsutomu、Tomita Shuhei、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 16 Pages: 307-307
- DOI
  10.1186/s12967-018-1679-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17H07023
[Journal Article] Clinical significance of the neutrophil-to-lymphocyte ratio (NLR) in endocrine therapy for stage IV breast cancer.2017
- Author(s)
  Kashiwagi S, Asano Y, Goto W, Takada K, Takahashi K, Noda S, Takashima T, Onoda N, Tomita S, Ohsawa M, Hirakawa K, Ohira M.
- Journal Title
  
  PLos One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0170634
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461957, KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K10559
[Journal Article] Prediction of survival after neoadjuvant chemotherapy for breast cancer by evaluation of tumor-infiltrating lymphocytes and residual cancer burden2017
- Author(s)
  Asano Yuka、Kashiwagi Shinichiro、Goto Wataru、Takada Koji、Takahashi Katsuyuki、Hatano Takaharu、Noda Satoru、Takashima Tsutomu、Onoda Naoyoshi、Tomita Shuhei、Motomura Hisashi、Ohsawa Masahiko、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Pages: 888-888
- DOI
  10.1186/s12885-017-3927-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17H07023
[Journal Article] Tumour blood vessel normalisation by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumour mouse model2017
- Author(s)
  Koyama S, Matsunaga S, Imanishi M, Maekawa Y, Kitano H, Takeuchi H, Tomita S
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 45621-45621
- DOI
  10.1038/srep45621
- NAID
  120006535012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-16K15524, KAKENHI-PROJECT-15H04724
[Journal Article] Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells2017
- Author(s)
  Kita Kazuaki、Shiota Masayuki、Tanaka Masako、Otsuka Asuka、Matsumoto Masaki、Kato Minoru、Tamada Satoshi、Iwao Hiroshi、Miura Katsuyuki、Nakatani Tatsuya、Tomita Shuhei
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 1820-1827
- DOI
  10.1111/cas.13318
- NAID
  130007900717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K15757
[Journal Article] Circulating tumor cell clusters-associated gene plakoglobin is a significant prognostic predictor in patients with breast cancer2017
- Author(s)
  Goto Wataru、Kashiwagi Shinichiro、Asano Yuka、Takada Koji、Takahashi Katsuyuki、Hatano Takaharu、Takashima Tsutomu、Tomita Shuhei、Motomura Hisashi、Ohsawa Masahiko、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Biomark Res
  
  Volume: 5 Pages: 19-19
- DOI
  10.1186/s40364-017-0099-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602
[Journal Article] Using TILs to Predict Therapeutic Effect of Chemotherapy (Pertuzumab, Trastuzumab, Docetaxel) on HER2-positive Breast Cancer.2017
- Author(s)
  Kashiwagi S, Asano Y, Goto W, Takada K, Takahashi K, Hatano T, Takashima T, Tomita S, Motomura H, Ohsawa M, Hirakawa K, Ohira M
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Pages: 5623-5630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08602
[Journal Article] Roles of hypoxia inducible factor-1α in the temporomandibular joint.2017
- Author(s)
  Mino-Oka A, Izawa T, Shinohara T, Mori H, Yasue A, Tomita S, Tanaka E
- Journal Title
  
  Arch Oral Biol
  
  Volume: 73(1) Pages: 274-281
- DOI
  10.1016/j.archoralbio.2016.10.028
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293436, KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-15K15757, KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-16H07019
[Journal Article] Reoxygenation with 100% Oxygen Following Hypoxia in Mice Causes Apoptosis2017
- Author(s)
  Nishimura Y, Ueki M, Imanishi M, Tomita S, Ueno M, Morishita J, Nishiyama T.
- Journal Title
  
  Shock
  
  Volume: 48 Pages: 590-594
- DOI
  10.1097/shk.0000000000000891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-16K18884
[Journal Article] Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice2017
- Author(s)
  Islam J, Sato S, Watanabe K, Watanabe T, Ardiansyah, Hirahara K, Aoyama Y, Tomita S, Aso H, Komai M, Shirakawa H
- Journal Title
  
  J Nutr Biochem
  
  Volume: 42 Pages: 43-50
- DOI
  10.1016/j.jnutbio.2016.12.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-17K08602
[Journal Article] 低酸素と生活習慣病2016
- Author(s)
  冨田修平，木平孝高，玉置俊晃
- Journal Title
  
  炎症と免疫
  
  Volume: 24 Pages: 26-31
- Data Source
  KAKENHI-PROJECT-15K15054
[Journal Article] Hypoxia-inducible factor-1α in smooth muscle cells protects against aortic aneurysms.2016
- Author(s)
  Imanishi M, Chiba Y, Tomita N, Matsunaga S, Nakagawa T, Ueno M, Yamamoto K, Tamaki T, Tomita S
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 36 Pages: 2158-2162
- DOI
  10.1161/atvbaha.116.307784
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15054
[Journal Article] 血管リモデリング形成における低酸素誘導因子の機能解析2016
- Author(s)
  今西正樹，冨田修平
- Journal Title
  
  血管
  
  Volume: 39 Pages: 127-132
- Data Source
  KAKENHI-PROJECT-15K15054
[Journal Article] Spontaneously hyperactive MEK-Erk pathway mediates paradoxical facilitation of cell proliferation in mild hypoxia.2015
- Author(s)
  Miyamoto L, Yagi Y, Hatano A, Kawazoe K, Ishizawa K, Minakuchi K, Tomita S, Tsuchiya K.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1850 Pages: 640-646
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15054
[Journal Article] A Long-Term High-Fat Diet Changes Iron Distribution in the Body, Increasing Iron Accumulation Specifically in the Mouse Spleen2015
- Author(s)
  Noriko Yamano, Yasumasa Ikeda, Minoru Sakama, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Licht Miyamoto, Shuhei Tomita, Koichiro Tsuchiya, Toshiaki Tamaki
- Journal Title
  
  J Nutr Sci Vitaminol
  
  Volume: 61 Issue: 1 Pages: 20-27
- DOI
  10.3177/jnsv.61.20
- NAID
  130005070829
- ISSN
  0301-4800, 1881-7742
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Spontaneously hyperactive MEK-Erk pathway mediates paradoxical facilitation of cell proliferation in mild hypoxia2015
- Author(s)
  Miyamoto L, Yagi Y, Hatano A, Kawazoe K, Ishizawa K, Minakuchi K, Tomita S, Tsuchiya K.
- Journal Title
  
  Biochim Biophys Acta Gen Subj
  
  Volume: 1850 Pages: 640-646
- DOI
  10.1016/j.bbagen.2014.12.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-15K07967
[Journal Article] The aryl hydrocarbon receptor and glucocorticoid receptor interact to activate human metallothionein 2A.2014
- Author(s)
  Sato S, Shirakawa H, Tomita S, Tohkin M, Gonzalez FJ, Komai M.
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 273(1) Pages: 90-99
- DOI
  10.1016/j.taap.2013.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590381
[Journal Article] Deletion of hypoxia-inducible factor-1α in adipocytes enhances glucagon-like Peptide-1 secretion and reduces adipose tissue inflammation.2014
- Author(s)
  Yoshitaka KIHIRA, Mariko MIYAKE, Manami HIRATA, Yoji HOSHINA, Kana KATO, Hitoshi SHIRAKAWA, Hiroshi SAKAUE, Noriko YAMANO, Yuki IZAWA-ISHIZAWA, Keisuke ISHIZAWA, Yasumasa IKEDA, Koichiro TSUCHIYA, Toshiaki TAMAKI, Shuhei TOMITA
- Journal Title
  
  PLoS One.
  
  Volume: 9
- DOI
  10.1371/journal.pone.0093856
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591333, KAKENHI-PROJECT-24790254, KAKENHI-PUBLICLY-25126718, KAKENHI-PROJECT-25860063, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Smooth muscle cell-specific Hif-1αdeficiency suppresses angiotensin II-induced vascular remodelling in mice2014
- Author(s)
  Imanishi M, Tomita S, Ishizawa K, Kihira Y, Ueno M, Izawa-Ishizawa Y, Ikeda Y, Yamano N, Tsuchiya K, Tamaki T.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: in press Pages: 460-468
- DOI
  10.1093/cvr/cvu061
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591203, KAKENHI-PROJECT-24790254, KAKENHI-PROJECT-25860063
[Journal Article] The ARNT-STAT axis regulates the differentiation of intestinal TCR αβ +CD8 αα + cells2014
- Author(s)
  Nakajima K, Maekawa K, Kataoka K, Ishifune C, Nishida J, Arimochi H, Yoshimoto T, Tomita S, Nagahiro S, Yasutomo K.
- Journal Title
  
  Nat Communications
  
  Volume: 4 Pages: 1-11
- DOI
  10.1038/ncomms3112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500958, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24590585, KAKENHI-PROJECT-24659595, KAKENHI-PUBLICLY-25118727
[Journal Article] Overexpressed HIF-2α in Endothelial Cells Promotes Vascularization and Improves Random Pattern Skin Flap Survival2014
- Author(s)
  Morimoto A, Tomita S, Imanishi M, Shioi G, Kihira Y, Izawa-Ishizawa Y, Takaku M, Hashimoto I, Ikeda Y, Nakanishi H, Tamaki T.
- Journal Title
  
  Plastic and Reconstructive Surgery Global Open
  
  Volume: 7
- DOI
  10.1097/gox.0000000000000083
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591203, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Characterization of silodosin and naftopidil in the treatment of bladder dysfunction in the spontaneously hypertensive rat2014
- Author(s)
  Saito M, Tsounapi P, Oikawa R, Shimizu S, Honda M, Sejima T, Kinoshita Y, Tomita S.
- Journal Title
  
  Neurourol Urodyn
  
  Volume: 22 Pages: 3822-3822
- DOI
  10.1038/srep03822
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24592431
[Journal Article] Olmesartan ameliorates urinary dysfunction in the spontaneously hypertensive rat via recovering bladder blood flow and decreasing oxidative stress.2014
- Author(s)
  Shimizu S, Saito M, Oiwa H, Ohmasa F, Tsounapi P, Oikawa R, Dimitriadis F, Martin TD, Satoh I, Kinoshita Y, Tomita S
- Journal Title
  
  Sci Rep
  
  Volume: 33 Pages: 350-357
- DOI
  10.1002/nau.22405
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-11J00118, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24592431, KAKENHI-PROJECT-26861271
[Journal Article] HIF-2α/ARNT complex regulates hair development via induction of p21(Waf1/Cip1) and p27(Kip1).2014
- Author(s)
  Imamura Y, Tomita S, Imanishi M, Kihira Y, Ikeda Y, Ishizawa K, Tsuchiya K, Tamaki T.
- Journal Title
  
  FASEB J.
  
  Volume: in press Pages: 2517-2524
- DOI
  10.1096/fj.13-244079
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591203, KAKENHI-PROJECT-25860063
[Journal Article] Nitrosonifedipine ameliorates angiotensin II-induced vascular remodeling via antioxidative effects、Naunyn-Schmiedeberg's Arch2013
- Author(s)
  Sakurada Takumi, et al
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol.
  
  Volume: 386 Pages: 29-39
- DOI
  10.1007/s00210-012-0810-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-23790298, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591203, KAKENHI-PROJECT-24790254
[Journal Article] Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodeling.2013
- Author(s)
  Nakayama T, Kurobe H, Sugasawa N, Kinoshita H, Higashida M, Matsuoka Y, Yoshida Y, Hirata Y, Sakata M, Maxfield M, Shimabukuro M, Takahama Y, Sata M, Tamaki T, Kitagawa T, Tomita S.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: 99 Pages: 705-715
- DOI
  10.1093/cvr/cvt146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249025, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-23592040, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-24390331, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24592068, KAKENHI-PROJECT-25670390
[Journal Article] Dietary iron restriction inhibits progression of diabetic 2 nephropathy in db/db mice2013
- Author(s)
  Ikeda Yasumasa, et al
- Journal Title
  
  Am J Physiol Renal Physiol.1
  
  Volume: 304 Pages: 1028-1036
- DOI
  10.1152/ajprenal.00473.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-23790298, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591203, KAKENHI-PROJECT-24790254
[Journal Article] 亜硝酸塩による腎保護作用(2013
- Author(s)
  土屋浩一郎、石澤啓介、宮本理人、堀ノ内裕也、池田康将、木平孝高、冨田修平、玉置俊晃
- Journal Title
  
  腎とフリーラジカル
  
  Volume: 11 Pages: 30-33
- Data Source
  KAKENHI-PROJECT-22590241
[Journal Article] Iron reduction by deferoxamine leads to amelioration of adiposity via the regulation of oxidative stress and inflammation in obese and type 2 diabetes KBCAy mice2012
- Author(s)
  Tajima S, Ikeda Y, Sawada K, Yamano N, Horinouchi Y, Kihira Y, Ishizawa K, Izawa-Ishizawa Y, Kawazoe K, Tomita S, Minakuchi K, Tsuchiya K, and Tamaki T
- Journal Title
  
  Am. J. Physiol. Endocrinol. Metab
  
  Volume: 302
- DOI
  10.1152/ajpendo.00033.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-22790864, KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-23790298
[Journal Article] Deferoxamine promotes angiogenesis via the activation of vascular endothelial cell function2011
- Author(s)
  Ikeda Y, Tajima S, Yoshida S, Yamano N, Kihira Y, Ishizawa K, Aihara K, Tomita S, Tsuchiya K and Tamaki T
- Journal Title
  
  Atherosclerosis
  
  Volume: 215 Pages: 339-347
- DOI
  10.1016/j.atherosclerosis.2011.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-21591140, KAKENHI-PROJECT-22790864, KAKENHI-PROJECT-23790089
[Journal Article] Protective effect of photodegradation product of nifedipine against tumor necrosis factor alpha-induced oxidative stress in human glomerular endothelial cells2011
- Author(s)
  Fukuhara Y, Tsuchiya K, Horinouchi Y, Tajima S, Kihira Y, Hamano S, Kawazoe K, Ikeda Y, Ishizawa K, Tomita S and Tamaki T
- Journal Title
  
  The Journal of Medical Investigation
  
  Volume: 59 Issue: 1,2 Pages: 118-126
- DOI
  10.2152/jmi.58.118
- NAID
  130004465233
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-23790089
[Journal Article] Pathophysiological Response to Hypoxia - From the Molecular Mechanisms of Malady to Drug Discovery:Inflammatory Responses of Hypoxia-Inducible Factor 1.ALPHA. (HIF-1.ALPHA.) in T Cells Observed in Development of Vascular Remodeling2011
- Author(s)
  Tomita S, et al
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 115 Issue: 4 Pages: 433-439
- DOI
  10.1254/jphs.10r22fm
  10.1254/jphs.10R22FM
- NAID
  10029893030
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-22790864, KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-23790298
[Journal Article] Antioxidant Effects of Photodegradation Product of Nifedipine2011
- Author(s)
  Horinouchi Y, Tsuchiya K, Taoka C, Tajima S, Kihira Y, Matsuda Y, Shishido K, Yoshida M, Hamano S, Kawazoe K, Ikeda Y, Ishizawa K, Tomita S, Tamaki T
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 59 Issue: 2 Pages: 1171-1173
- DOI
  10.1248/cpb.59.208
- NAID
  130000405517
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-23390026, KAKENHI-PROJECT-23790089
[Journal Article] Basic fibroblast growth factor regulates glucose metabolism through glucose transporter 1 induced by hypoxia-inducible factor-1alpha in adipocytes2011
- Author(s)
  Kihira Y, Yamano N, Izawa-Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T, Tomita S
- Journal Title
  
  Int. J. Biochem. Cell. Biol
  
  Volume: 43 Pages: 1602-11
- DOI
  10.1016/j.biocel.2011.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-22790864, KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-23790298
[Journal Article] 生体の低酸素応答と病態-血管リモデリングにおける転写因子HIFの関与-2011
- Author(s)
  冨田修平, 他
- Journal Title
  
  四国医学雑誌
  
  Volume: 67 Pages: 3-6
- Data Source
  KAKENHI-PROJECT-21590335
[Journal Article] Angiotensin ii receptor blocker attenuates PDGF-induced mesangial cell migration in a receptor-independent manner2010
- Author(s)
  Ishizawa K, Izawa-Ishizawa Y, Dorjsuren N, Miki E, Kihira Y, Ikeda Y, Hamano S, Kawazoe K, Minakuchi K, Tomita S, Tsuchiya K and Tamaki T
- Journal Title
  
  Nephrol Dial
  
  Volume: 25 Pages: 364-372
- DOI
  10.1093/ndt/gfp520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-22790864
[Journal Article] Effect of angiotensin II on iron-transporting protein expression and subsequent intracellular labile iron concentration in human glomerular endothelial cells2010
- Author(s)
  Tajima S, Tsuchiya K, Horinouchi Y, Ishizawa K, Ikeda Y, Kihira Y, Shono M, Kawazoe K, Tomita S, Tamaki T
- Journal Title
  
  Hypertens Res
  
  Volume: 33 Pages: 713-721
- DOI
  10.1038/hr.2010.63
- NAID
  10026520343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-22790864
[Journal Article] Role of Hif-1a in T cells as a negative regulator in development of vascular remodeling2010
- Author(s)
  Kurobe H, Urata M, Ueno M, Ueki M, Ono S, Izawa-Ishizawa Y, Fukuhara Y, Lei Y, Ripen AM, Kanbara T, Aihara K, Ishizawa K, Akaike M, Gonzalez FJ, Tamaki T, Takahama Y, Yoshizumi M, Kitagawa T, Tomita S
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 30 Pages: 210-217
- DOI
  10.1161/atvbaha.109.192666
- Data Source
  KAKENHI-PROJECT-21590335
[Journal Article] Drug discovery for overcoming CKD : Development of drugs on endathelial cell Protection for overcoming CKD2009
- Author(s)
  Ishizawa K, Yamaguchi K, Horinouchi Y, Fukuhara Y, Tajima S, Hamano S, Tomita S, Tsuchiya K, and Tamaki T
- Journal Title
  
  JPharmaco1 Sc 109
  
  Pages: 14-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] 低酸素応答転写因子の組織リモデリングへの関与2009
- Author(s)
  冨田修平, 他
- Journal Title
  
  日薬理誌 133
- Data Source
  KAKENHI-PROJECT-21590335
[Journal Article] 低酸素応答転写因子の組織リモデリングヘの関与2009
- Author(s)
  冨田修平, 他
- Journal Title
  
  日薬理誌 133
  
  Pages: 298-298
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] 低酸素応答転写因子の組織リモデリングへの関与2009
- Author(s)
  冨田修平, 玉置俊晃
- Journal Title
  
  日薬理誌
  
  Pages: 133-298
- NAID
  10025740819
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Gene expression profile of third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus develoPment2009
- Author(s)
  Sultana DA, Tomita S, Hamada M, Itisanaga Y, Kitahama Y, Nguyen VK, Hirai S, Ohigashi I, Nitta S, Amagai T, Takahashi S and Takahama Y(*These two authors equally contributed to this work.)
- Journal Title
  
  Blood (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Quercetin Glucuronide Inhibits Cell Migration and Proliferation by Platelet-Derived Growth Factor in Vascular Smooth Muscle Cells2009
- Author(s)
  Ishizawa K, Izatva-Ishizatva Y, Ohnishi S, Motobayshi Y, Kawazoe K, Hamano S, Tsuchiya K, Tomita S, Minakuchi K, and Tamaki T
- Journal Title
  
  JPharmacol Sci 109
  
  Pages: 257-264
- NAID
  10025734551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Gene expression profile of third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development.2009
- Author(s)
  Tomita S, et al.
- Journal Title
  
  Blood 113(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Tocotrienol inhibits angiogenic factors secretion from human colorectal adenocarcinoma cells via suppressing hypaxia inducible factor-1α2008
- Author(s)
  Shibata A, Nakagawa K, Sookwong P, Tsuduki T, Tomita S, Shirakawa H, Kornai M, and Miyazawa T
- Journal Title
  
  J Nutr 138
  
  Pages: 2136-2142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] The expression of osteopantin is increased in vessels with blood-brain barrier impairment2008
- Author(s)
  Isvanaga Y, Ueno M, Ueki M, Huang CL, Tomita S, Okamoto Y, Ogawa T, Ueda N, Maekatiwa N and Sakamato H
- Journal Title
  
  Neuropathol Appl Neurobiol 34
  
  Pages: 145-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Law-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the arylhydrocarbon receptor-mediated pathway inmouse liver2008
- Author(s)
  Sato, S., Shirakawa, H., Tomita, S., Ohsaki, Y., Haketa, K., Tooi, 0., Santo, N., Tohkin, M., Furukawa, Y., Frank J. Gonzalez and Kamai, M
- Journal Title
  
  Toaicol Appl Pharmacol 229
  
  Pages: 10-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] PDGFによるメサンギウム細胞遊走に対するオルメサルタンの抑制効果とその分子機構2008
- Author(s)
  石澤啓介, 三木恵里加, 石澤有紀, 大西秀樹, Narantungalag Darjsuren, 元林有紀, 山口邦久, 土屋浩一郎, 冨田修平, 玉置俊晃
- Journal Title
  
  血管 31
  
  Pages: 59-64
- NAID
  10021261870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Dietary doses of nitrite restore the circulating nitricoxide level and improve renal injury in L-NAME-induced hypertensive rats2008
- Author(s)
  Kanematsu Y, Yamaguchi K, Ohnishi H, Motohayashi Y, Ishizawa K, Izawa Y, Katvazoe K, Kondo S, Kagami S, Tomita S, Tsuchiya K and Tamaki T
- Journal Title
  
  AmJ Physiol Renal Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Effect of iron-quercetin complex on reduction of nitrite in vitro and in vivo system2008
- Author(s)
  Ohnishi H, Iwanaga S, Kawazoe K, Ishizawa K, Orino S, Tomita S, Tsuchiya K, Kanematsu Y, Harada N, Mori K, Ishikawa Y and Tamaki T
- Journal Title
  
  J Agric Food Chem 56
  
  Pages: 10092-10108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Big Mitogen-Activated Protein Kinasel(BMKI/extracellular signal regulated kinas 5(ERK5)is involved in platelet-derived growth factor(PDGF)-induced vascular smooth muscle cell migration2007
- Author(s)
  Izawa Y, Yoshizumi M, Ishizawa K, Fujita Y, Kondo S, Kagami S, Kawazoe K, Tsuchiya K, Tomita S and Tamaki T
- Journal Title
  
  Hypertens Res 30
  
  Pages: 1107-1117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload2007
- Author(s)
  Sano M, Minamino T, Toko H, Miyauchi H, Orima M, Qin Y, AkazaNa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y and Komuro I
- Journal Title
  
  Nature 446
  
  Pages: 444-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590281
[Journal Article] Thymic involution produced by diesel exhaust particles and their constituents in mice.2006
- Author(s)
  Tomita S
- Journal Title
  
  Toxicological and Environmental Chemistry. 88
  
  Pages: 113-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Journal Article] Diesel exhaust particles and their components that are independent of polycyclic aromatic hydrocarbons cause thymic involution in mice.2006
- Author(s)
  Tomita, S.
- Journal Title
  
  J. Toxico. Environ. Chem. 88
  
  Pages: 113-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590436
[Journal Article] Thymic involution produced by diesel exhaust particles and their constituents in mice.2006
- Author(s)
  Tomita S, Maekawa S, Rahman M, Saito F, Kizu R, Tohi K, Ueno T, Nakase H, Gonzalez FJ, Hayakawa K, Korenaga T, Takahama Y.
- Journal Title
  
  Toxicol Environ Chemistry. 88
  
  Pages: 113-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Journal Article] Diesel exhaust particles and their components that are independent of polycyclic aromatic hydrocarbons cause thymic involution in mice. J.2006
- Author(s)
  Tomita, S.
- Journal Title
  
  Toxico.Environ.Chem. 88
  
  Pages: 113-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590436
[Journal Article] Diesel exhaust particles an dtheir components that are independent of polycyclic aromatic hydrocarbons cause thymic involution in mice.2006
- Author(s)
  Tomita, S.
- Journal Title
  
  J.Toxico.Environ.Chem. 88
  
  Pages: 113-124
- Data Source
  KAKENHI-PROJECT-17590436
[Journal Article] Diesel exhaust particles and their components that are independent of polycyclic aromatic hydrocarbons cause thymic involution in mice.2006
- Author(s)
  Tomita, S.
- Journal Title
  
  J. Toxico. Environ. Chem. In press
- Data Source
  KAKENHI-PROJECT-17590436
[Journal Article] T cell-specific disruption of aryl hydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2378-tetrachlorodibenzo-p-dioxin-induced thymic involution.2003
- Author(s)
  Tomita, S., et al.
- Journal Title
  
  J.Immunol 171
  
  Pages: 4113-4120
- Data Source
  KAKENHI-PROJECT-15790171
[Journal Article] T cell-specific disruption of aryl hydrocarbon receptor nuclear translocator gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution.2003
- Author(s)
  Tomita S, Jiang HB, Ueno T, Takagi S, Tohi K, Maekawa S, Miyatake A, Furukawa A, Gonzalez FJ, Takeda J, Ichikawa Y, Takahama, Y.
- Journal Title
  
  J Immunol. 171
  
  Pages: 4113-4120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Journal Article] T cell-specific disruption of aryl hydrocarbon receptor nuclear translocator gene causes resistance to 2,3,7,8-tetrachlodibenzo-p-dioxin-induced thymic involution.2003
- Author(s)
  Tomita S
- Journal Title
  
  Journal of Immunology. 171
  
  Pages: 4113-4120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Journal Article] Defective brain development in mice lacking HIF-1 alpha in neural cells.2003
- Author(s)
  Tomita S, Ueno M, Sakamoto M, Kitahama Y, Ueki M, Maekawa N, Sakamoto H, Gassmann M, Kageyama R, Ueda N, Gonzalez FJ, Takahama Y.
- Journal Title
  
  Mol Cell Biol. 23
  
  Pages: 6739-6749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Journal Article] Defective brain development in mice lacking the Hif-1alpha gene in neural cells.2003
- Author(s)
  Tomita, S., et al.
- Journal Title
  
  Mol.Cell.Biol. 23
  
  Pages: 6739-6749
- Data Source
  KAKENHI-PROJECT-15790171
[Journal Article] Defective brain development in mice lacking HIF-1 alpha in neural cells.2003
- Author(s)
  Tomita S
- Journal Title
  
  Molecular and Cellular Biology. 23
  
  Pages: 6739-6749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Patent] 腫瘍関連マクロファージ賦活化剤2019
- Inventor(s)
  冨田修平・松永慎司・西出峻治・内田潤次
- Industrial Property Rights Holder
  冨田修平・松永慎司・西出峻治・内田潤次
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-143014
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08602
[Patent] 抗癌剤の抗腫瘍効果の増強剤、癌治療剤、及び癌治療用医薬組成物2016
- Inventor(s)
  冨田修平・松永慎司
- Industrial Property Rights Holder
  冨田修平・松永慎司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-171299
- Filing Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15054
[Patent] 胸腺器官発生因子TOF1及びTOF2両遺伝子とその用途2004
- Inventor(s)
  高浜洋介, 冨田修平
- Industrial Property Rights Holder
  徳島大学, 高浜洋介, 冨田修平
- Patent Publication Number
  2006-101828
- Filing Date
  2004
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043237
[Presentation] リナグリプチンは心筋梗塞後のDPP-4非依存的に左室リモデリングを抑制する2020
- Author(s)
  山口雄大、泉康雄、塩田正之、松永慎司、德留健太郎、三浦克之、岩尾洋、冨田修平
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] 胎児期低酸素ストレス負荷による自閉症様症状の発現には抑制性シナプス関連遺伝子の発現低下が関与する2020
- Author(s)
  徳留健太郎、松永慎司、山口雄大、冨田修平
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Alteration the phenotype of tumor-infiltrating macrophages via the PHD-HIF axis inhibits tumor growth in mice.2020
- Author(s)
  Shunji Nishide, Shinji Matsunaga, Takehiro Yamaguchi, Norihiko Takeda, Junji Uchida, Katsuyuki Miura, Tatsuya Nakatani and Shuhei Tomita
- Organizer
  Keystone Symposia -Hypoxia: Molecules, Mechanisms and Disease-
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] リナグリプチンは心筋梗塞後のDPP-4非依存的に左室リモデリングを抑制する2020
- Author(s)
  山口雄大、泉康雄、塩田正之、松永慎司、德留健太郎、三浦克之、岩尾洋、冨田修平
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08958
[Presentation] 低酸素シグナルのがん微小環境に及ぼす影響2020
- Author(s)
  冨田修平
- Organizer
  第20回日本抗加齢医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07072
[Presentation] PHD阻害剤による腫瘍浸潤マクロファージの表現型変化は腫瘍環境改善を誘導する2020
- Author(s)
  松永慎司、西出峻治、徳留健太郎、山口雄大、冨田修平
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] リポポリサッカライド誘発性腎障害に対するヨヒンビンの効果2020
- Author(s)
  下川隆臣、山形雅代、林耕平、冨田修平、米田耕造
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Hypoxia-inducible factor-1α regulates energy fuel metabolism and mediates metabolic plasticity during ammonia stress response in ovarian cancer stem-like cells.2018
- Author(s)
  Shojiro Kitajima, Kian Leong Lee, Hiroki Hikasa, Shinji Matsunaga, Takehiro Yamaguchi, Shuhei Tomita, Marito Araki, Hiroyuki Kato and Lorenz Poellinger
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] The role of HIF-1 in the development of renal fibrosis with special reference to HIF-1 dependent gene expression.2018
- Author(s)
  Kabei K., Nozaki M., Uchida J., Nakatani T., Tomita S. and Miura K.
- Organizer
  ISN Frontiers Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08958
[Presentation] Prolyl Hydroxylase inhibitor repaired chemo-sensitivity through tumor blood vessel normalization in tumor mouse model.2018
- Author(s)
  Shinji Matsunaga, Shunji Nishide, Masayuki Shiota, Takehiro Yamaghchi, Shojiro Kitajima, Katsuyuki Miura and Shuhei Tomita.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] The role of HIF-1 in the development of renal fibrosis in mouse UUO model with special reference to HIF-1 dependent gene expression.2018
- Author(s)
  Kabei K., Osada-Oka M.,Nozaki M., Shiota M., Tanaka M., Tomita S. and Miura K.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Effects of hypoxia inducible factor alpha prolyl hydroxylase inhibitor on the development of renal fibrosis in mouse unilateral ureteral obstruction model.2018
- Author(s)
  Miura K., Kabei K., Tateishi Y., Osada-Oka M., Shiota M., Matsunaga S., Nishide S., Yamaguchi T. and Tomita S.
- Organizer
  第92回日本薬理学会年会　2019年3月14－16日、大阪
- Data Source
  KAKENHI-PROJECT-17K08958
[Presentation] The role of HIF-1 in the development of renal fibrosis with special reference to HIF-1 dependent gene expression.2018
- Author(s)
  Kabei K., Nozaki M., Uchida J., Nakatani T., Tomita S. and Miura K
- Organizer
  ISN Frontiers 2018, Feb.22-25, Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] The role of HIF-1 in the development of renal fibrosis in mouse UUO model with special reference to HIF-1 dependent gene expression.2018
- Author(s)
  Kabei K., Osada-Oka M., Nozaki M., Shiota M., Tanaka, M., Tomita S. and Miura K.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July1-6, 2018, Kyoto, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08958
[Presentation] Dipeptidyl Peptidase-4 (DPP-4) inhibition Attenuates Cardiac Dysfunction after Myocardial Infarction Independently of DPP-4.2018
- Author(s)
  Yamaguchi T, Izumi Y, Shiota M, Tanaka M, Osada-Oka M, Matsunaga S, Kitajima S, Miura K, Iwao H, Tomita S
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] 肺血管内皮細胞由来低酸素応答因子 HIF が肺高血圧症の病態形成に果たす役割2018
- Author(s)
  冨田修平，山口雄大，松永慎司
- Organizer
  第47回日本心脈管作動物質学会年会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Role of hypoxia inducible factor-1 in Vascular Remodeling2017
- Author(s)
  Shuhei Tomita
- Organizer
  第94回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] 血管リモデリングにおける平滑筋由来HIF-1αの役割2017
- Author(s)
  冨田修平
- Organizer
  第46回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] 血管リモデリングにおける平滑筋由来HIF-1αの役割2017
- Author(s)
  冨田修平
- Organizer
  第46回日本心脈管作動物質学会
- Place of Presentation
  琉球大学（沖縄県中頭郡）
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] 血管リモデリングにおける低酸素応答性転写因子HIF-1αの役割2016
- Author(s)
  冨田修平
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] Normalization of tumor blood vessel induced by neovascularization drug.2016
- Author(s)
  松永慎司、小山哲史、井口道代、今西正樹、冨田修平
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜（横浜パシフィコ）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] Role of hypoxia-inducible factor-1alpha in vascular remodeling.2016
- Author(s)
  Shuhei Tomita
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] The effect of antioxidants treatment on Seminal Vesicles and Vas Deferens function in the Diabetes Mellitus rat model.2015
- Author(s)
  Panagiota Tsounapi, Masashi Honda, Shinji Hirano, Bunya Kawamoto, Katsuya Hikita, Kuniyasu Muraoka, Michiyo Iguchi, Masaki Imanishi, Shinji Matsunaga, Shuhei Tomita, Takehiro Sejima, Atsushi Takenaka.
- Organizer
  The 103rd Annual Meeting of the Japanese Urological Association
- Place of Presentation
  Kanazawa(Kanazawa Art Hall（石川県金沢市）)
- Year and Date
  2015-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] Pathophysiological responses to hypoxia in vascular remodeling by hypoxia-inducible factor-1.2015
- Author(s)
  Tomita S.
- Organizer
  The 11th World Congress of the International Society for Adaptive Medicine
- Place of Presentation
  Yonago (Yonago Convention Center（鳥取県米子市）)
- Year and Date
  2015-05-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] 亜硝酸塩による腎保護作用とその機序2013
- Author(s)
  土屋浩一郎、宮本理人、石澤啓介、冨田洋輔、山根萌、木平孝高、池田康将、玉置俊晃
- Organizer
  第66回日本酸化ストレス学会
- Place of Presentation
  ウインク愛知(愛知県)
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-22590241
[Presentation] 亜硝酸による腎保護作用における AMPK の意義2013
- Author(s)
  宮本理人、山根萌、河野舞、冨田洋輔、石澤啓介、玉置俊晃、土屋浩一郎
- Organizer
  第42回日本心脈管作動物質学会
- Place of Presentation
  奈良県新公会堂(奈良県)
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-22590241
[Presentation] 疾患に伴う血管リモデリング進展過程に置ける低酸素応答性転写因子HIFの役割2012
- Author(s)
  冨田修平
- Organizer
  第８５回日本生化学会
- Place of Presentation
  福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-24590381
[Presentation] Pathophysiological responses to hypoxia in vascular remodeling by hypoxia-inducible factors.2012
- Author(s)
  Tomita S
- Organizer
  ISOTT 2012
- Place of Presentation
  NOVOTEL Hotel, Bruges, Belgium
- Invited
- Data Source
  KAKENHI-PROJECT-24590381
[Presentation] Inhibition of Adipocyte Hypertrophy by Deferoxiamine Diabetic KKAy mice2011
- Author(s)
  Tajima S, Ikeda Y, Yamano N, Tsuchiya K, Ishizawa Y, Kihira Y, Ishizawa K, Kawazoe K, Tomita S, Minakuchi K, Tamaki T.
- Organizer
  High Blood Pressure Research Scientific Sessions 2011 Scientific Sessions
- Place of Presentation
  Florida, USA
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Preconditionining of mice with prolyl hydroxylase inhibitor, dimethyloxalylglycine, prevents skin flap necrosis2011
- Author(s)
  Takaku M, Tomita S, Kihira Y, Hashimoto I, Nakanishi H, Tamaki T.
- Organizer
  AHA scientific sessions 2011
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Hypoxia-inducible Factor-1αDeficiency in Smooth Muscle Cells Suppresses AngiotensinII-induced Vascular Remodeling in Mice2011
- Author(s)
  Imanishi M, Ishizawa K, Kihira Y, Ikeda Y, Yamano N, Ishizawa Y, Tsuciya K, Tamaki T, Tomita S.
- Organizer
  High Blood Pressure Research Scientific Sessions 2011 Scientific Sessions
- Place of Presentation
  Orlando, Florida
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Estrogen action on iron metabolism2011
- Author(s)
  Ikeda Y, Tajima S, Yamano N, Kihira Y, Ishizawa K, Tomita S, Tsuchiya K, Tamaki T.
- Organizer
  The Endocrine Society 2011
- Place of Presentation
  Boston, USA
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Nitorosonifedipine is a new class drug to improves angiotensin II-induced vascular remodeling2011
- Author(s)
  Ishizawa K, Sakurada T, Imanishi M, Fujii S, Ishizawa Y, Kihira Y, Ikeda Y, Tomita S, Tsuchiya K, Tamaki T
- Organizer
  European Society of Cardiology Congress 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] 生体の低酸素応答と病態2011
- Author(s)
  冨田修平
- Organizer
  第242回徳島医学会学術集会
- Place of Presentation
  徳島市(聴島大学長井記念ホール)
- Year and Date
  2011-02-13
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Preconditioning of mice with a PHD inhibitor, dimethyloaxylglycine, prevent skin flap necrosis2011
- Author(s)
  Takaku M, Tomita S, Kurobe H, Hashimoto I, Nakanishi H, Tamaki T
- Organizer
  ISSOT(International Society on Oxygen Transport to Tissue) 2011
- Place of Presentation
  Washington DC
- Year and Date
  2011-08-25
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Heparin Cofactor II Promotes Angiogenesis via an AMPK-eNOS Signaling Pathway2011
- Author(s)
  Ikeda Y, Aihara KI, Yoshida S, Kihira Y, Ishizawa K, Izawa-Ishizawa Y, Tomita S, Sata M, Akaike M, Kato S, Matsumoto T, Tamaki T.
- Organizer
  High Blood Pressure Research Scientific Sessions 2011 Scientific Sessions
- Place of Presentation
  Orlando, Florida
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Increment intracellular labile iron enhances angiotensin-induced intracellular adhesion molecule-1(ICAM-1) expression in human glomerular endothelial cells2011
- Author(s)
  Imanishi M, Tajima S, Kihira Y, Ishizawa K, Ikeda Y, Kondo S, Kagami S, Tomita S, Ikeda Y, Tsuchiya K, Tamaki S.
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver
- Year and Date
  2011-04-10
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Smooth Muscle Cell-Specific Hypoxia-Inducible Factor-1αDeficiency Attenuates Angiotensin II-Induced Vascular Remodeling in Mice2011
- Author(s)
  Imanishi M, Ishizawa K, Kihira Y, Ikeda Y, Yamano Y, Ishizawa Y, Tsuchiya K, Tamaki T, Tomita S
- Organizer
  AHA scientific sessions 2011
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Glucose Metabolism of Adipocytes is Regulated by Basic Fibroblast Growth Factor via Hypoxia-inducible Factor-1α2011
- Author(s)
  Yamaguchi K, Kihira Y, Yamano N, Izawa-Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tomita S, Tamaki T
- Organizer
  High Blood Pressure Research Scientific Sessions 2011 Scientific Sessions
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Characterization of mice lacking HIF-1α gene in renal ischemia-reperf usion injury2011
- Author(s)
  Shuhei Tomita
- Organizer
  ISSOT (International Society on Oxygen Transport to Tissue) 2011
- Place of Presentation
  Georgetown University Conference Center (Washington DC)
- Year and Date
  2011-08-25
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] 病態に観られる低酸素応答の意義-血管リモデリングにおけるT細胞のHIF-1の役割-2010
- Author(s)
  冨田修平, 他
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪市
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Deferoxamine, an iron chelator, promotes angiogenesis after ischemic hind limb through Akt-eNOS-dependent pathway2010
- Author(s)
  Tajima S, Ikeda Y, Kihira Y, Ishizawa K, Kawazoe K, Tomita S, Minakuchi K, Tamaki T, Tsuchiya K
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto, June
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Amelioration of acute tubular necrosis in ischemic acute renal failure was impaired in mice lacking hypoxia inducible factor-1 gene2010
- Author(s)
  Tamaki T, Yamaguchi K, Kihira Y, Ikeda Y, Ishizawa K, Tsuchiya K, Tomita S.
- Organizer
  International Society of Nephrology Nexus symposium 2010
- Place of Presentation
  Kyoto
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] 痛態に観られる低酸素応答の意義-血管リモデリングにおけるT細胞のHIF-1の役割-2010
- Author(s)
  冨田修平, 他
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪市(大阪国際会議揚)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Iron elimination ameliorated glucose tolerance through suppression of oxidative stress and inflammation on fat in diabetic mice2010
- Author(s)
  Ikeda Y, Tajima S, Yamano N, Kihira Y, Ishizawa K, Tomita S, Tsuchiya K, Tamaki T.
- Organizer
  American Heart Association Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Endothelial-targeted hypoxia-inducible factor-1b(HIF-1b) loss-of function alleviates the monocrotaline-induced pulmonary hypertension in mice2010
- Author(s)
  Tomita S, Urata M, Fukuhara Y, Kihira Y, Ikeda Y, Ishizawa K, Tsuchiya K, Kitagawa T, Tamaki T
- Organizer
  American Heart Association Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Nitroso-Nifedipine is A New Class Drug to Protect Endotherial Function for Overcoming Organ Damage2010
- Author(s)
  Ishizawa K, Imanishi M, Horinouchi Y, Fukuhara Y, Izawa-Ishizawa Y, Ikeda Y, Kihira Y, Tomita S, Tsuchiya K, Tamaki T
- Organizer
  The 23rd Scientific Meeting of the International Society of Hypertension GLOBAL CARDIOVASCULAR RISK REDUCTION
- Place of Presentation
  Vancouver
- Year and Date
  2010-11-23
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Deferoxamine, an iron chelator, enhances angiogenesis through Akt-eNOS pathway in endothelial cells2010
- Author(s)
  Ikeda Y, Tajima S, Yamano N, Kihira Y, Ishizawa K, Tomita S, Tsuchiya K, Tamaki T.
- Organizer
  American Heart Association Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Endothelial-targeted hypoxia-inducible factor-1b (HIF-1b) loss-of function alleviates the monocrotaline-induced pulmonary hypertension in mice.2010
- Author(s)
  Tomita S, et al.
- Organizer
  American Heart Association Scientific Sessions 2010
- Place of Presentation
  Chicago
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] 動脈硬化に伴う血管リモデリングに対してT細胞のHIF-1αは抑制的に機能する2010
- Author(s)
  冨田修平, 他
- Organizer
  第31回日本炎症再生医学会年会
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Global gene expression analyses in renal ischemia-reperfusion injury(IRI) from mice lucking Hif-1a gene2010
- Author(s)
  Tamaki T, Yamaguchi K, Kihira Y, Ikeda Y, Ishizawa K, TsuchiyaK, Kondo S, Kagami S and Tomita S
- Organizer
  Annual meeting for American Society of Nephrology
- Place of Presentation
  Colorado
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Deferoxamine, an iron chelator, promotes angiogenesis after ischemic hind limb through Akt-eNOS-dependent pathway2010
- Author(s)
  Ikeda Y, Kihira Y, Ishizawa K, Tomita S, Tsuchiya K, Tamaki T
- Organizer
  XX World Congress ISHR 2010 KYOTO
- Place of Presentation
  Kyoto
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Role of HIF-1b in endothelial cells in monocrotalineinduced pulmonary hypertension in mice2010
- Author(s)
  Fukuhara Y, Tomita S, Imamura Y, Horinouchi Y, Imanishi M, Sakurada T, Kitagawa T, Tamaki T
- Organizer
  The 16th World Congress of Basic and Clinical Pharmacology WorldPharma 2010
- Place of Presentation
  Copenhagen
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Basic fibroblast growth factor upregulates hypoxia inducible factor 1 and glucose transporter 1 in adipose cells2010
- Author(s)
  Kihira Y, Tomita S, Ikeda Y, Ishizawa K, Tsuchiya K and Tamaki T
- Organizer
  The 16th World Congress of Basic and Clinical Pharmacology WorldPharma 2010
- Place of Presentation
  Copenhagen
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] IRON DERIVATION AMELIORATES GLUCOSE TOLERANCE THROUGH REDUCTION OF OXIDATIVE STRESS AND INFLAMMATION IN DIABETIC KKAY MICE2010
- Author(s)
  Tajima S, Ikeda Y, Yamano N, Tsuchiya K, Kihira Y, Ishizawa K, Kawazoe K, Tomita S, Minakuchi K, Tamaki T
- Organizer
  2010 American Physiological Society Conference Inflammation, Immunity and Cardiovascular Disease
- Place of Presentation
  Colorado
- Year and Date
  2010-11-07
- Data Source
  KAKENHI-PROJECT-21590335
[Presentation] Hypoxia -inducible factor -1の機能不全は腎虚血再潅流障害の回復を妨げる2009
- Author(s)
  冨田修平, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Hypoxia-inducible factor-1の機能不全は腎虚血再灌流障害の回復を妨げる2009
- Author(s)
  冨田修平、山口邦久、石澤啓介、今村優子、福原弥生、土屋浩一郎、玉置俊晃
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 動脈硬化病態進展におけるT細胞の低酸素応答性因子の役割2009
- Author(s)
  冨田修平、黒部裕嗣、玉置俊晃
- Organizer
  第5回宮崎サイエンスキャンプ
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 肺高血圧症モデルマウスにおける血管内皮細胞の低酸素応答転写因子(HIF1-β)の役割2009
- Author(s)
  浦田将久、福原弥生、冨田修平、黒部裕嗣、吉田誉、石澤啓介、北川哲也、玉置俊晃
- Organizer
  第38回日本心脈管作動物質学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 児期早期心臓・大血管手術時の胸腺摘除による術後免疫細胞発生の検討2008
- Author(s)
  黒部裕嗣、富永崇司、来島敦史、北市隆、早渕康信、長嶋光樹、冨田修平、江川善康、高浜洋介、北川哲也
- Organizer
  第27回日本胸腺研究会
- Place of Presentation
  さいたま
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 高血圧ラットモデルにおけるnifedipine代謝物による臓器保護作用の検討2008
- Author(s)
  恒石鉄平、石澤啓介、福原弥生、Narantungalag Dorjsuren、大野呂知浩、山口邦久、冨田修平、土屋浩一郎、玉置俊晃
- Organizer
  第113回日本薬理学会近畿支部会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] ヒト血管内皮細胞における細胞接着分子発現に対するnifedipine代謝物の影響2008
- Author(s)
  福原弥生、石澤啓介、堀ノ内裕也、山口邦久、冨田修平、土屋浩一郎、玉置俊晃
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 腎虚血再潅流障害における低酸素応答性転写因子の分子解析の試み2008
- Author(s)
  冨田修平
- Organizer
  第16回大阪市大フォーラム
- Place of Presentation
  大阪
- Year and Date
  2008-08-01
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Hypoxia-Inducible Factor-1 α Ameliorates Ischemic Acute Renal Failure and Has a Relation with a Recovery from Acute Tubular Necrosis2008
- Author(s)
  Yamaguchi K, Ishizawa K, Tomita S, Tsuchiya K, Konda S, Kagansi S, Tamaki T
- Organizer
  Annual meeting for American Society of Nephrology, Philadelphia
- Place of Presentation
  Pennsylvania
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 腎虚血再灌流障害における低酸素応答性転写因子の分子解析の試み2008
- Author(s)
  冨田修平
- Organizer
  第16回大阪市大フォーラム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 肺高血圧症モデルマウスにおける血管内皮細胞の低酸素応答転写因子(HIF1-β)の役割2008
- Author(s)
  浦田将久、冨田修平、黒部裕嗣、吉田誉、石澤啓介、Frank Gonzalez、北川哲也、玉置俊晃
- Organizer
  第29回日本炎症再生医学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 動脈硬化の病態進展におけるT細胞のHIF-laの役割2008
- Author(s)
  .冨田修平、黒部裕嗣、浦団将久、福原弥生、石澤有紀、神原保、石澤啓介、上屋浩一郎、北川哲也、玉置俊晃
- Organizer
  第114回日本薬理学会近畿部会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 食餌性亜硝酸による生体内NO生成における鉄イオンの役割2008
- Author(s)
  土屋浩一郎、大西秀樹、岩永智史、堀之内裕也、田島壮一郎、三口弘介、石澤啓介、山口邦久、浜野修一、冨田修平、玉置俊晃
- Organizer
  第113回日本薬理学会近畿支部会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Hypoxia-inducible factor-la is a tumor suppressor in early stages in a mouse model of multi-step islet carinogenesis. Keystone Symposia(Molecular, Cellular, Physiological, and Pathogenic Responses to Hypoxia2008
- Author(s)
  Inoue, M., Takeda, T., Endo, H., Tomita, S.
- Organizer
  Vancouver
- Place of Presentation
  British Columbia
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 低容量ダイオキシンによる脂質代謝に関する遺伝子の発現変化2008
- Author(s)
  佐藤祥子、白川仁、冨田修平、駒井三千夫
- Organizer
  第31回日本分子生物学会第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] L-MME慢性投与ラットにおける臓器障害に及ぼすnifedipine代謝物の影響2008
- Author(s)
  石澤啓介、福原弥生、堀ノ内裕也、恒石鉄平、山口邦久、冨田修平、土屋浩一郎、玉置俊晃
- Organizer
  第18回日本循環薬理学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 蛍光色素PhenGreenSKを用いた細胞内遊離2価鉄測定法2008
- Author(s)
  濱本磨以、久住祥子、富澤彩智、田島壮一郎、石澤啓介、冨田修平、山口邦久、庄野正行、吉村好之、滝口祥令、土屋浩一郎、玉置俊晃
- Organizer
  第20回腎とフリーラジカル研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 第三咽頭嚢発現遺伝子の探索から明らかになったMafBの胸線発生への関与2007
- Author(s)
  冨田修平、Dil Afroz Sultana、平井宗一、Nguyen Van Khan、濱田理人、高橋智、高浜洋介
- Organizer
  Kyoto T Cell Conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Hif-la in T cells plays a crucial role in the progression of arteriosclerosis and artery intimal thickening2007
- Author(s)
  Kuorabe, H., Urata, M., Izawa, Y., Fukuhara, Y., Kanbara, T., Aihara, K.I., Akaike, M., Gonzalez, F., Matsumoto, T., Tamaki, T., Kitagawa, T., Yoshizumi, M., Tomita, S
- Organizer
  AHA Scientific Sessions
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 新生児期胸腺摘除が免疫形成に与える影響2007
- Author(s)
  黒部裕嗣、富永崇司、来島敦史、早渕康信、長嶋光樹、冨田修平、江川善康、北川哲也、高浜洋介
- Organizer
  第26回日本胸腺研究会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Role of MafB in the development of the thymus2007
- Author(s)
  TOMITA Shuhei, SULTANA DilAfroz, HIRAI Shuichi, KHANG Nguyen Van, TAKAHASHI Sataru, , TAKAHAMA Yousuke
- Organizer
  第37回目本免疫学会総会
- Place of Presentation
  品川
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 胸腺初期発生における低酸素応答の役割2007
- Author(s)
  平井宗一、冨田修平、Nguyen Van Khang、高浜洋介
- Organizer
  第6回四国免疫フォーラム
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] ヒトメタロチオネイン2A遺伝子の転写制御に関するAhレセプターとグルココルチコイドレセプターの相互作用2007
- Author(s)
  佐藤洋子、白川仁、冨田修平、駒井三千夫
- Organizer
  第30回日本分子生物学会第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] The role of HIF-1 in fetal thymus developmont2007
- Author(s)
  HIRAI Shuichi, TOMITA Shuhei, NGUYEN Van Khang, TAKAHAMA Yousuke
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  品川
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] 第三咽頭嚢発現遺伝子の探索から明らかになったMafBの胸腺発生への関与2007
- Author(s)
  冨田修平
- Organizer
  Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Role of MafB in the development of the thymus2007
- Author(s)
  TOMITA Shuhei
- Organizer
  日本免疫学会総会
- Place of Presentation
  品川
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19590281
[Presentation] Pathophysiological responses to hypoxia in vascular remodeling by hypoxia-inducible factor-1
- Author(s)
  Shuhei Tomita
- Organizer
  The 11th WORLD CONGRESS of the International Society fro ADAPTIVE MEDICINE
- Place of Presentation
  Yonago, Japan
- Year and Date
  2015-05-27 – 2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-24590381

1. TAMAKI Tamaki (80179879)

# of Collaborated Projects: 4 results

# of Collaborated Products: 61 results
2. ISHIZAWA Ishizawa (60398013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
3. TAKAHAMA Yousuke (20183858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. Ueki Masaaki (20213332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 市川佳幸 (60028355)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 松永慎司 (30704910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
7. TSUCHIYA Koichiro (70301314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. HAMANO Shuichi (60530392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FURUKAWA Aizo (80304583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NISHIYAMA TAKASHI (60243771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Miura Katsuyuki (00183624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. 奥山英策 (10263899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 西村与志郎 (10566970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大坪里織 (10568819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 山田克己 (20714645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 安藤維洋 (50719482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岡田直己 (70403293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 竹本恭彦 (20364002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 首藤太一 (20295687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 葭山稔 (30240956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 山口雄大 (40726080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. 福本一夫 (20897392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. URATA Urata

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. FUKUHARA Yayoi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
25. NAKAYAMA Taisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. IMANISHI Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
27. IKEDA Yasumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
28. KASHIWAGI Shinichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 25 results
29. IZUMIYA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. KUROBE Hirotsugu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. TAJIMA Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. KINOSHITA Yukako

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. SHIMIZU Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. MORIYA Taiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 田中昌子(橘昌子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
36. 石澤有紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
37. 藤岡正喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 木平孝高

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
39. 阪上浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 浅野有香

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
41. 藤田寿一

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
42. 井澤俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. 岩浅亮彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 森崎珠実

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
45. 前川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
46. 岡真優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 片岡佳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 有持秀喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 善本隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 島袋充生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 北川哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 木下肇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 佐田政隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 西出峻治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
55. 田中栄二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 泰江章博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 森浩喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 齋藤源顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
59. 清水翔吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tomita Shuhei 冨田 修平

TOMITA Tomita 冨田 修平

富田 修平 トミタ シュウヘイ

Research Projects

Research Products

Co-Researchers

PHD阻害薬による自然免疫活性化に基づく抗腫瘍メカニズムの解明と治療標的の探索Principal Investigator

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喫煙による早期血管障害におけるmicroRNAの関与と機序

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Review Section

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Basic research of cancer therapy by improving anticancer drug sensitivity through tumor vascular remodelingPrincipal Investigator

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Angiogenesis in renal fibrosis

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Mechanism of organ damage caused by 100% oxygen reoxygenation after adult hypoxia and establishment of its treatment strategy

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Tumor blood vessel normalization by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumor mouse modelPrincipal Investigator

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Reoxygenation with 100% oxygen following hypoxia in mice causes apoptosis

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Mechanism of hypoxia-induced transformation in endothelial cellsPrincipal Investigator

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The renal protective effects of nitrite salts in diabetic nephropathy model rats.

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Mechanisms of hypoxia-induced transformation in endothelial cellsPrincipal Investigator

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CharaGterization of the evoked inflammation via hypoxic response in endothelial cellsPrincipal Investigator

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The roles of HIF-1α in T cell-dependent immune responsesPrincipal Investigator

Principal Investigator

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神経系細胞系譜的HIF-1α遺伝子欠失マウスの作製と解析Principal Investigator

Principal Investigator

Tomita Shuhei 冨田修平

TOMITA Tomita 冨田修平

富田修平トミタシュウヘイ