WAGA Kazuo 和賀一雄

Researcher Number	00285917
Affiliation (based on the past Project Information) *help	2008: 獨協医科大学, 医学部, 講師 2001 – 2004: Dokkyo University School of Medicine, Department of Hermatology, Lecturer, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Hematology / Hematology / Biological Sciences
Keywords	Except Principal Investigator AML1 / 白血病 / TEL / MEN / CtBP / EVI-1 / MLL / TGFβ / ノックアウトマウス / ERK … More / ドミナント・ネガティブ効果 / 転写因子 / PTPRR / p53 / JNK / Smad3 / EBPα / C / ノックインマウス / リン酸化 / inv(12) / アポトーシス / GM細胞 / ドミナント・ネガティブ / トランスジェニックマウス / Creリコンビナーゼ / コンディショナルマウス / Lck / コンディショナル / isoform / chromosomal abnormality / leukemia / transcription factor / ETS / 12p13 / t(12;21) / PPO / ベンチジン / UT-7 / アイソフォーム / 染色体異常 / conditional knock-out mice / TGBβ / ノックイン・マウス / モデルマウス / 胸腺 / Creリコンビネース / ノック・イン / ノックイン / 造血幹細胞腫瘍 / 胎生致死 / ノックアウト / コンディショナルノックアウト / apoptosis / Evi-1 / t(3;21) / キメラ型転写因子 / t(11;19) / 転写伸長因子 / MEM / GATA-1 / PU.1 / 胎仔肝造血 / Evi1 / ピストン脱アセチル化酵素 / 転写活性 / 慢性骨髄性白血病 / 分化抑制 / LG-3 / replating / レトロウイルス / MOZ / アセチル化 / 骨髄異形成症候群 / 染色体転座 / がん抑制因子 / EVI1 / RUNX1 / Lox-P配列 / ES / mSin3A / 分化 / MEL細胞 / 12p13転座 / 32D細胞 / UT7 / STAT3 / inv(12)(p13q13) / T細胞 / LCK / Tリンパ球 Less

Analysis of mechanisms in hematopoietic regulation and leukemia development
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
発生工学的手法を用いた白血病関連転写因子TELの機能解析
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Mechanisms in hematopoiesis and leukemogenesis by the transcription factor TEL
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
12P13転座型白血病の分子機構の解析
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Dokkyo Medical University
コンディショナルマウスを用いたヒト白血病関連転写因子の機能解析
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Development of new immune cell therapies with human leukemia model mouse.
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo University School of Medicine
Analysis of molecular mechanisms in leukemogenesis by chimeric transcription factors
- Principal Investigator
  
  NAKAMURA Yuichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo University School of Medicine
  The University of Tokyo

All 2006 2004 2003 2002

All Journal Article

[Journal Article] TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways2006
- Author(s)
  Yamagata T, Maki K, Waga K, Mitani K
- Journal Title
  
  Biochem Biophys Res Comm 347
  
  Pages: 517-526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Functional analysis of a dominant-negative DETS TEL/ETV6 isoform.2004
- Author(s)
  Sasaki, K., Nakamura, Y., Maki, K., Waga, K., Nakamura, F., Arai, H., Imai, Y., Hirai, H., Mitani, K.
- Journal Title
  
  Biochem Biophys Res Comm 317
  
  Pages: 1128-1137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Leukemia-related transcription factor TEL is negatively regulated through ERK-induced phosphorylation.2004
- Author(s)
  Maki, K., Arai, H., Waga, K., Sasaki, K., Nakamura, F., Imai, Y., Kurokawa, M., Hirai, H., Mitani K.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 3227-3237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] TEL/AML1 shows dominant-negative effects over TEL as well as AML1.2004
- Author(s)
  Gunji, H., Waga, K., Nakamura, F., Maki, K., Sasaki, K., Nakamura, Y., Mitani, K.
- Journal Title
  
  Biochem Biophys Res Comm 322
  
  Pages: 623-630
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells2003
- Author(s)
  Waga, K.
- Journal Title
  
  Oncogene 22
  
  Pages: 59-68
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells.2003
- Author(s)
  Waga, K., Nakamura, Y., Maki, K., Arai, H., Yamagata, T., Sasaki, K., Kurokawa, M., Hirai, H., Mitani K.
- Journal Title
  
  Oncogene 22
  
  Pages: 59-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Functional regulation of TEL by p38-induced phosphorylation.2002
- Author(s)
  Arai, H., Maki, K., Waga, K., Sasaki, K., Nakamura, Y., Imai, Y., Kurokawa, M.,.Hirai, H., Mitani, K.
- Journal Title
  
  Biochem Biophys Res Comm 299
  
  Pages: 116-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308

1. MITANI Kinuko (50251244)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
2. MAKI Kazuhiro (50337391)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
3. NAKAMURA Yuichi (20227896)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
4. SASAKI Ko (60282638)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. 小川誠司 (60292900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 千葉滋 (60212049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WAGA Kazuo 和賀 一雄

Research Projects

Research Products

Co-Researchers

Analysis of mechanisms in hematopoietic regulation and leukemia development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

発生工学的手法を用いた白血病関連転写因子TELの機能解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms in hematopoiesis and leukemogenesis by the transcription factor TEL

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

12P13転座型白血病の分子機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

コンディショナルマウスを用いたヒト白血病関連転写因子の機能解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new immune cell therapies with human leukemia model mouse.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanisms in leukemogenesis by chimeric transcription factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways2006

Author(s)

Journal Title

Data Source

[Journal Article] Functional analysis of a dominant-negative DETS TEL/ETV6 isoform.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Leukemia-related transcription factor TEL is negatively regulated through ERK-induced phosphorylation.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] TEL/AML1 shows dominant-negative effects over TEL as well as AML1.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Functional regulation of TEL by p38-induced phosphorylation.2002

Author(s)

Journal Title

Description

Data Source

WAGA Kazuo 和賀一雄