Tanaka Nobutada 田中信忠

… Alternative Names

TANAKA Nobutada 田中信忠

田中信忠タナカノブタダ

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Researcher Number	00286866
Other IDs	https://orcid.org/0000-0001-5365-4698
Affiliation (Current)	2024: 北里大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 北里大学, 薬学部, 教授 2015 – 2019: 昭和大学, 薬学部, 准教授 2011 – 2013: 昭和大学, 薬学部, 准教授 2008 – 2009: Showa University, 薬学部, 准教授 2000 – 2007: 昭和大学, 薬学部, 講師 2000: 昭和大, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Structural biochemistry / Basic Section 49010:Pathological biochemistry-related / Basic Section 38020:Applied microbiology-related / Applied microbiology / Parasitology (including Sanitary zoology) / Physical pharmacy / Structural biochemistry Except Principal Investigator Biological Sciences / Basic Section 57030:Conservative dentistry-related / Drug development chemistry / Morphological basic dentistry / Bacteriology (including Mycology)
Keywords	Principal Investigator X線 / 結晶構造解析 / 構造生物学 / 立体構造 / ドラッグデザイン / 転移 / がん / 結晶化 / サイトカイン / 腫瘍 … More / 抗菌剤 / ペプチダーゼ / 糖非発酵性細菌 / マラリア / 阻害剤 / 結晶 / インターフェロン / リボヌクレアーゼ / 希少疾患 / ゴーシェ病 / グルコセレブロシダーゼ / アロステリックシャペロン / 多剤耐性菌 / 歯周病 / 非メバロン酸経路 / 結晶構造 / オリゴアデニル酸 / 化学療法 / 抗ウイルス機構 / アンキリンリピート … More Except Principal Investigator 歯周病 / 構造生物学 / タンパク質 / 結晶構造解析 / アンキリンリピート / 2-5A / P. gingivalis / ジペプチジルペプチダーゼ / 糖尿病 / ジペプチジルペプチターゼ / Porphyromonas gingivalis / 阻害選択性の向上 / 構造安定性低下 / SNPs / 抗癌剤耐性克服 / 分子モデリング / 構造活性相関 / AKR1B10 / SNP / 抗癌剤 / アルドケト還元酵素 / S46 peptidase / Perio / Antibiotics / DPP / 抗菌薬 / ペプチダーゼ / S46 / DPP11 / 薬剤耐性 / X線結晶解析 / β-ラクタマーゼ / 蛋白質 / 酵素 / 抗生物質 / 感染症 / 医薬品開発 / X線結晶構造解析 / 酵素阻害薬 / SAH hydrolase / 抗マラリア薬 / マラリア / 核酸 / 抗ウイルス機構 / インターフェロン / リボヌクレアーゼ / X線 / 結晶化 / 結晶構造 / 2-5Aシステム / RNase L / 抗ウィルス機構 Less

選択的ジペプチジルペプチダーゼ阻害剤による糖尿病関連歯周炎に対する創薬研究
- Principal Investigator
  
  野中由香莉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Development of allosteric chaperone compounds based on structural information of the target enzymesPrincipal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kitasato University
ジペプチジルペプチダーゼを標的とした新規歯周病医薬開発
- Principal Investigator
  
  野中由香莉
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Development of a novel inhibitor cocktail targeting peptidases from sugar non-fermentative bacteriaPrincipal Investigator
- Principal Investigator
  
  Tanaka Nobutada
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Kitasato University
  Showa University
Development of novel antibiotics targeting peptidases of non-fermenting gram negative rods.Principal Investigator
- Principal Investigator
  
  Tanaka Nobutada
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Showa University
Development of novel anticancer agents targeting survival strategy of cancer cells
- Principal Investigator
  
  Endo Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu Pharmaceutical University
Structural and functional studies of dipeptidyl aminopeptidases from periodontal pathogen.
- Principal Investigator
  
  SAKAMOTO YASUMITSU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Iwate Medical University
Structure-activity relationship studies of the enzymes belonging to the non-mevalonate pathway of Plasmodium falciparumPrincipal Investigator
- Principal Investigator
  
  TANAKA Nobutada
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Showa University
Ultra high resolution Xray crystallographic study for antibiotic mechanisms of action and resistance
- Principal Investigator
  
  NUKAGA Michiyoshi
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Josai International University
インターフェロン誘導型抗ウイルス機構2-5Aシステムにおける機能制御の構造的基盤Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Showa University
細胞運動刺激因子の立体構造に基づく腫瘍転移抑制剤の開発Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Showa University
抗マラリア薬の開発を志向したマラリア原虫由来加水分解酵素の基質認識機構の解明Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Showa University
X線結晶構造解析を基盤とする熱帯熱マラリア原虫酵素の特異的阻害薬の開発
- Principal Investigator
  
  北出幸夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
がん細胞運動刺激因子AMFとATXの立体構造と機能Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Showa University
インターフェロン誘導型抗ウイルス機構主要酵素リボヌクレアーゼLの構造と機能
- Principal Investigator
  
  中村和郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Showa University
がん細胞運動刺激因子による細胞外受容体認識機構の解明Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Showa University
自己分泌型がん細胞運動刺激因子の構造生物学的研究Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Showa University
インターフェロン誘導型抗ウイルス機構主要酵素ヒトリボヌクレアーゼLの立体構造解析Principal Investigator
- Principal Investigator
  
  田中信忠
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Showa University
抗ウィルスマシーナリー-2-5Aシステム-の構造生物学
- Principal Investigator
  
  中西雅之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University

[Journal Article] 5-<i>C</i>-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease2022
- Author(s)
  Kato Atsushi、Nakagome Izumi、Kanekiyo Uta、Lu Tian-Tian、Li Yi-Xian、Yoshimura Kosuke、Kishida Mana、Shinzawa Kenta、Yoshida Tomoki、Tanaka Nobutada、Jia Yue-Mei、Nash Robert J.、Fleet George W. J.、Yu Chu-Yi
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Issue: 3 Pages: 2329-2341
- DOI
  10.1021/acs.jmedchem.1c01673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02876, KAKENHI-PROJECT-21K06451
[Journal Article] Novel angular naphthopyrone formation by Arp1p dehydratase involved in <i>Aspergillus fumigatus</i> melanin biosynthesis2021
- Author(s)
  Nambu Natsuki、Tsai Huei‐Fung、Chang Yun C.、Kwon‐Chung K. J.、Yoshida Tomoki、Tanaka Nobutada、Tomoda Hiroshi、Ebizuka Yutaka、Fujii Isao
- Journal Title
  
  Environmental Microbiology Reports
  
  Volume: 13 Issue: 6 Pages: 822-829
- DOI
  10.1111/1758-2229.13013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03995, KAKENHI-PROJECT-19H02876
[Journal Article] Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 72021
- Author(s)
  22)Akihiro Nakamura, Yoshiyuki Suzuki, Yasumitsu Sakamoto, Saori Roppongi, Chisato Kushibiki, Natsuri Yonezawa, Masato Takahashi, Yosuke Shida, Hiroaki Gouda, Takamasa Nonaka, Nobutada Tanaka, Wataru Ogasawara
- Journal Title
  
  scinentific reports
  
  Volume: 11 Issue: 1 Pages: 7929-7929
- DOI
  10.1038/s41598-021-86965-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-19H02876
[Journal Article] Fragment-based discovery of the first non-peptidyl inhibitor for dipeptidyl aminopeptidase with chymotrypsin-like domain from pathogens2020
- Author(s)
  Sakamoto, Y., Suzuki, Y., Nakamura, A., Sekiya, M., Ogasawara, W., & Tanaka, N.
- Journal Title
  
  Photon Factory Highlights 2019
  
  Volume: - Pages: 56-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02876
[Journal Article] Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase2019
- Author(s)
  YasumitsuSakamoto,YoshiyukiSuzuki,AkihiroNakamura,YurieWatanabe,MizukiSekiya,SaoriRoppongi,ChisatoKushibiki,IppeiIizuka,OsamuTani,HitoshiSakashita,KojiInaka,HiroakiTanaka,MitsuguYamada,KazunoriOhta,NobuyukiHonma,YosukeShida,WataruOgasawara,MayumiNakanishi-Matsui,TakamasaNonaka,HiroakiGouda & NobutadaTanaka
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 13587-13587
- DOI
  10.1038/s41598-019-49984-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06629, KAKENHI-PROJECT-18K06661, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-19H02876
[Journal Article] The Crystal Structure of Peptidase Toward Drug Discovery2019
- Author(s)
  阪本泰光、六本木沙織、鈴木義之、石原司、日高興士、中村彰宏、本間宣行、小笠原渉、田中信忠
- Journal Title
  
  International journal of microgravity science and application
  
  Volume: 36 Issue: 1 Pages: 360106
- DOI
  10.15011//jasma.36.360106
- NAID
  130007842629
- ISSN
  2188-9783
- Year and Date
  2019-01-31
- Language
  Japanese
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-16K08322
[Journal Article] Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues2018
- Author(s)
  Roppongi Saori、Suzuki Yoshiyuki、Tateoka Chika、Fujimoto Mayu、Morisawa Saori、Iizuka Ippei、Nakamura Akihiro、Honma Nobuyuki、Shida Yosuke、Ogasawara Wataru、Tanaka Nobutada、Sakamoto Yasumitsu、Nonaka Takamasa
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2714-2714
- DOI
  10.1038/s41598-018-21056-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04902, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-15K14231, KAKENHI-PROJECT-16K08322
[Journal Article] Periplasmic form of dipeptidyl aminopeptidase IV from Pseudoxanthomonas mexicana WO24: purification, kinetic characterization, crystallization and X‐ray crystallographic analysis2017
- Author(s)
  Saori Roppongi Chika Tateoka Mayu Fujimoto Ippei Iizuka Saori Morisawa Akihiro Nakamura Nobuyuki Honma Yoshiyuki Suzuki Yosuke Shida Wataru Ogasawara Nobutada Tanaka Yasumitsu Sakamoto Takamasa Nonaka
- Journal Title
  
  Acta Crystallographica Section F
  
  Volume: 73 Issue: 11 Pages: 501-606
- DOI
  10.1107/s2053230x17014911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04902, KAKENHI-PROJECT-17H03790, KAKENHI-PROJECT-15K14231, KAKENHI-PROJECT-16K08322
[Journal Article] RNaseLにおける酵素活性化機構解明を目指した構造生物学的研究2017
- Author(s)
  田中信忠
- Journal Title
  
  SAR News
  
  Volume: 32 Pages: 10-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04902
[Journal Article] Crystal Structure of Dipeptidyl Peptidase 11 from Porphyromonas gingivalis: The Molecular Basis of Substrate Specificity among the Family S46 Peptidases2016
- Author(s)
  Sakamoto, Y. and Tanaka, N.
- Journal Title
  
  Photon Factory Highlights 2015
  
  Volume: - Pages: 56-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04902
[Journal Article] 糖非発酵グラム陰性細菌由来新規ジペプチド産生酵素の構造と機能2016
- Author(s)
  阪本泰光、野中孝昌、鈴木義之、小笠原渉、田中信忠
- Journal Title
  
  日本結晶学会誌
  
  Volume: 58 Pages: 221-227
- NAID
  130005267922
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H04902
[Journal Article] Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity.2015
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Yamada M, Ohta K, Gouda H, Nonaka T, Ogasawara W, Tanaka N.
- Journal Title
  
  Scientific Reports
  
  Volume: 87 Issue: 1 Pages: 11151-11151
- DOI
  10.1038/srep11151
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis.2015
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Gouda H, Nonaka T, Ogasawara W, Tanaka N.
- Journal Title
  
  Acta Crystallogr F Struct Biol Commun.
  
  Volume: 71 Issue: 2 Pages: 206-210
- DOI
  10.1107/s2053230x15000424
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] Binding modes of reverse fosmidomycin analogs towards the antimalarial target IspC2014
- Author(s)
  Konzuch, S., Umeda, T., Held, J., Hähn, S., Brücher, K., Lienau, C., Behrendt, C.T., Gräwert, T., Bacher, A., Illarionov, B., Fischer, M., Mordmuller, B., Tanaka, N., and Kurz, T.
- Journal Title
  
  J. Med. Chem.
  
  Volume: (submitted)
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of dipeptidyl aminopeptidase BII from Pseudoxanthomonas Mexicana WO24.2014
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Okada, H., Nonaka, T.,　Morikawa, Y., Nakamura, K.T., Ogasawara. W., and Tanaka, N.*
- Journal Title
  
  Acta Crystallogr. Section F
  
  Volume: 70 Pages: 221-224
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] Identification of the catalytic triad of dipeptidyl aminopeptidase BII, a member of family S46 of exopeptidases that are closely related to clan PA endopeptidases.2014
- Author(s)
  Suzuki, Y., Sakamoto, Y., Tanaka, N., Okada, H., Morikawa, Y., and Ogasawara, W.*
- Journal Title
  
  Sci. Rep.
  
  Volume: 4
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] S46 peptidases are the first exopeptidases to be members of clan PA.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 4977-4977
- DOI
  10.1038/srep04977
- NAID
  120006832415
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462872
[Journal Article] 抗マラリア薬の開発を目指した構造生物学的研究2013
- Author(s)
  田中信忠、梅田知伸、日下部吉男、中西雅之、北出幸夫、中村和郎
- Journal Title
  
  薬学雑誌
  
  Volume: 133 Pages: 527-537
- NAID
  130003361946
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] 抗マラリア薬の開発を指向した熱帯熱マラリア原虫由来ホスミドマイシン標的酵素の結晶構造解析2012
- Author(s)
  梅田知伸、日下部吉男、田中信忠
- Journal Title
  
  日本結晶学会誌
  
  Volume: 54 Pages: 107-112
- NAID
  10030631972
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH2012
- Author(s)
  Sundaram K, Endo S, Matsunaga T, Tanaka N, Hara A, El-Kabbani O.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun.
  
  Volume: 68 Pages: 400-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] Molecular basis of fosmidomycin’s action on the human malaria parasite Plasmodium falciparum.2011
- Author(s)
  Umeda, T., Tanaka, N., Kusakabe, Y., Nakanishi, M., Kitade, Y., & Nakamura, K.T.
- Journal Title
  
  Scientific Reports
  
  Volume: 1(9) Issue: 1 Pages: 1-8
- DOI
  10.1038/srep00009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590495
[Journal Article] Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-function relationship of the inhibitors.2006
- Author(s)
  Tanaka, N.et al.
- Journal Title
  
  J.Mol.Biol. 356
  
  Pages: 312-324
- Data Source
  KAKENHI-PROJECT-17012021
[Journal Article] Crystallization of the N-terminal ankyrin repeat domain of the 2-5A dependent endoribonuclease, RNase L.2005
- Author(s)
  Tanaka, N. et al.
- Journal Title
  
  Protein Peptide Lett. 12(in press)
- Data Source
  KAKENHI-PROJECT-15030237
[Journal Article] 新規抗マラリア薬の開発を志向したマラリア原虫由来加水分解酵素の結晶構造解析2005
- Author(s)
  田中信忠
- Journal Title
  
  日本結晶学会誌 47
  
  Pages: 211-215
- NAID
  10016467903
- Data Source
  KAKENHI-PROJECT-17770094
[Journal Article] Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L.2004
- Author(s)
  Tanaka, N. et al.
- Journal Title
  
  EMBO J. 23
  
  Pages: 3929-3938
- Data Source
  KAKENHI-PROJECT-15030237
[Journal Article] Crystal structure of s-adenosyl-L-homocysteine hydrolase from the human malaria parasite Plasmodium falciparum2004
- Author(s)
  Nobutada Tanaka
- Journal Title
  
  J.Mol.Biol. 343
  
  Pages: 1007-1017
- Data Source
  KAKENHI-PROJECT-16017239
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of Plasmodium falciparum s-adenosyl-L-homocysteine hydrolase2004
- Author(s)
  Nobutada Tanaka
- Journal Title
  
  Protein and Peptide Letters 11
  
  Pages: 201-205
- Data Source
  KAKENHI-PROJECT-16017239
[Presentation] A water-mediated hydrogen bond network facilitates an exceptionally strong preference for asparagine in the S2 subsite of dipeptidyl peptidase 7 from Stenotrophomonas maltophilia2023
- Author(s)
  Yasumitsu Sakamoto, et al., and Nobutada Tanaka
- Organizer
  26th Congress and General Assembly of the International Union of Crystallography
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] STRUCTURE AND SUBSTRATE RECOGNITION MECHANISM OF S46 PEPTIDASES2023
- Author(s)
  Nobutada Tanaka, Yasumitsu Sakamoto, Akihiro Nakamura, Yoshiyuki Suzuki, and Wataru Ogasawara
- Organizer
  12th GENERAL MEETING OF THE INTERNATIONAL PROTEOLYSIS SOCIETY
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] Fragment-based discovery of the first nonpeptidyl inhibitor of dipeptidyl peptidase 11 from Porphyromonas gingivalis2023
- Author(s)
  Nobutada Tanaka, et al., and Yasumitsu Sakamoto
- Organizer
  26th Congress and General Assembly of the International Union of Crystallography
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] In silico フラグメントマッピング法を利用したマラリア原虫の酵素pfDXRに対する新規阻害剤の探索2022
- Author(s)
  中込泉, 長谷川桃子, 山乙教之, 田中信忠
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 多剤耐性菌Stenotrophomonas maltophilia DPP7に対する抗菌薬開発に向けた阻害剤開発の構造基盤2022
- Author(s)
  阪本泰光, 中村彰宏, 鈴木義之, 六本木沙織, 櫛引千里, 米澤夏里, 高橋聖人, 志田洋介, 合田浩明, 野中孝昌, 田中信忠, 小笠原渉
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] In silico解析と親和性測定に基づいたlysosomal acid α-glucosidase (GAA)選択特性を有するイミノ糖のデザイン研究2022
- Author(s)
  加藤敦, 中込泉, 畑瑞希, 新澤健太, 名取良浩, 吉村祐一, 田中信忠
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] インシリコ・フラグメントマッピング法によるタンパク質-タンパク質間相互作用阻害剤の探索2022
- Author(s)
  小澤新一郎, 北村祐万, 広野修一, 田中信忠
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] アロステリック・サイトは正に荷電したアミノ酸残基を好む2022
- Author(s)
  山乙教之, 茂原理沙, 木村亮祐, 田中信忠
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 水和サイト解析を用いたTRIM24阻害剤のバーチャルスクリーニング2022
- Author(s)
  吉田智喜, 田中信忠
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 病原性細菌由来Dipeptidyl peptidaseの基質P2残基の嗜好性と認識機構の分子基盤2021
- Author(s)
  中村彰宏、阪本泰光、鈴木義之、六本木沙織、志田洋介、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 実験的に決定されたタンパク質-フラグメント複合体立体構造に基づくin silicoフラグメント・マッピング法の開発2021
- Author(s)
  山乙教之、広野修一、田中信忠
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 多剤耐性菌Stenotrophomonas maltophiliaに抗菌活性を示すジペプチド誘導体の開発2021
- Author(s)
  日高興士、橋本大聖、関拓海、櫻井有紀、阪本泰光、六本木沙織、關谷瑞樹、中村彰宏、鈴木義之、小笠原渉、田中信忠、宮崎杏奈、北條恵子、津田裕子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] キモトリプシン様ペプチダーゼを標的とするフラグメント創薬による非ペプチド系阻害剤の探索2021
- Author(s)
  阪本泰光、鈴木義之、中村彰宏、關谷瑞樹、六本木沙織、櫛引千里、谷修、山田貢、本間宣行、志田洋介、小笠原渉、中西真弓、野中孝昌、合田浩明、田中信忠
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] ゴーシェ病治療薬の開発を目指したたβ-glucocerebrosidaseに対する新規allosteric activatorの探索2021
- Author(s)
  中込泉、加藤敦、廣瀬花穂、島立優奈、畑瑞希、山乙教之、田中信忠、広野修一
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 水和サイト解析を用いたリガンドドッキング計算精度向上のための試み2021
- Author(s)
  吉田智喜、広野修一、田中信忠
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] タンパク質-フラグメント複合体X線構造に基づくin silicoフラグメント・マッピング法2021
- Author(s)
  山乙教之, 広野修一, 田中信忠
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] インフルエンザウイルスRNAポリメラーゼのサブユニット間相互作用阻害剤のバーチャルスクリーニング2021
- Author(s)
  大岩瑞季, 小澤新一郎, 田中信忠
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] In silicoフラグメントマッピング法を用いた新規ATAD2阻害剤の探索2021
- Author(s)
  越智拓仁, 吉田智喜, 田中信忠
- Organizer
  第49回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] Development of a 3DPharmacophore Model for P-gpSubstrates using in silico Fragment Mapping Method2021
- Author(s)
  Harutoshi Kato, Noriyuki Yamaotsu, Mika Nabeno, Nao Torimoto, Haruko Miyoshi, Tomoko Watanabe, NobutadaTanaka, Shuichi Hirono
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] ポンペ病の原因酵素であるGAAの変異部位がDNJのシャペロン効果に及ぼす影響について2021
- Author(s)
  加藤敦、今枝秀貴、畑瑞希、中込泉、広野修一、田中信忠
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] Development of antimicrobial dipeptides targeting dipeptidyl peptidase 7 of Stenotrophomonas maltophilia2020
- Author(s)
  Koushi Hidaka, Taisei Hashimoto, Takumi Seki, Yuki Sakurai, Yasumitsu Sakamoto, Saori Roppongi, Mizuki Sekiya, Akihiro Nakamura, Wataru Ogasawara, Yoshiyuki Suzuki, Nobutada Tanaka, Anna Miyazaki, Keiko Hojo, & Yuko Tsuda
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] 感染症治療薬開発を目指したタンパク質の立体構造解析2020
- Author(s)
  田中信忠
- Organizer
  東京工業大学化学生命科学研究所講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] タンパク質の立体構造に基づく分子機構解明と阻害剤開発2020
- Author(s)
  田中信忠
- Organizer
  第45回白金シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] Fragment-based discovery of inhibitory compounds of bacterial proteases for the development of the noel antibiotics.2019
- Author(s)
  Akihiro Nakamura et al., Nobutada Tanaka, and Wataru Ogasawara
- Organizer
  Tsukuba Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02876
[Presentation] クスリ創りの新時代へ　～宇宙実験・アカデミア創薬・ロボット創薬のコラボレーションによる新薬創製への挑戦～2019
- Author(s)
  阪本泰光、田中信忠、石原司
- Organizer
  「きぼう」利用シンポジウム
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] ジペプチジルアミノペプチダーゼ4ファミリーの立体構造比較研究2019
- Author(s)
  六本木沙織、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Pseudoxanthomonas mexicana WO24由来Dipeptidyl aminopeptidase IVの構造・機能解析2018
- Author(s)
  中村彰宏、本間宣行、六本木沙織、鈴木義之、志田洋介、阪本泰光、飯塚一平、伊中浩治、田仲広明、木平清人、山田貢、吉崎泉、合田浩明、野中孝昌、田中信忠、小笠原渉
- Organizer
  第12回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] X線結晶構造に基づく多剤耐性菌由来DPP-7阻害剤の設計と評価　-国際宇宙ステーションで抗菌薬を開発する-2018
- Author(s)
  関拓海、奥野優香、櫻井有紀、日高興士、宮崎杏奈、北條恵子、六本木沙織、阪本泰光、伊藤康広、鈴木義之、小笠原渉、田中信忠、木平清人、山田貢、吉崎泉、田仲広明、伊中浩治、津田裕子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Pseudoxanthomonas mexicana WO24由来Dipeptidyl aminopeptidase IVの基質認識機構の解明2018
- Author(s)
  中村彰宏、本間宣行、六本木沙織、鈴木義之、志田洋介、阪本泰光、飯塚一平、伊中浩治、田仲広明、木平清人、山田貢、吉崎泉、合田浩明、野中孝昌、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] 微生物ジペプチジルアミノペプチダーゼIVの結晶構造解析2018
- Author(s)
  六本木沙織、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] 微生物Dipeptidyl aminopeptidase IVの結晶構造解析2018
- Author(s)
  六本木沙織、鈴木義之、館岡千佳、藤本真友、森澤さおり、飯塚一平、中村彰宏、本間宣行、伊藤康広、志田洋介、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  2017年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Elucidation of substrate recognition mechanism of dipeptidyl aminopeptidase IV from Gram-negative bacteria Pseudoxanthomonas mexicana WO242018
- Author(s)
  Akihiro Nakamura, Nobuyuki Honma, Saori Roppongi, Yoshiyuki Suzuki, Yosuke Shida, Yasumitsu Sakamoto, Koji Inaka, Hiroaki Tanaka, Kiyoito Kihira, Mitsugu Yamada, Izumi Yoshioka, Hiroaki Gouda, Takamasa Nonaka, Nobutada Tanaka, Wataru Ogasawara
- Organizer
  7th International GIGAKU conference in Nagaoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] 部位特異的変異導入解析によるFamily S46ペプチダーゼの基質認識残基の同定2018
- Author(s)
  本間宣行、中村彰宏、六本木沙織、鈴木義之、志田洋介、阪本泰光、飯塚一平、伊中浩治、田仲広明、木平清人、山田貢、吉崎泉、合田浩明、野中孝昌、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Crystal structures of dipeptidyl aminopeptidase IV from non-fermenting gram negative rods.2017
- Author(s)
  Roppongi, S., Tateoka, C., Suzuki, Y., Ito, Y., Fujimoto, M., Morisawa, S., Iizuka, I., Ogasawara, W., Tanaka, N., Sakamoto, Y., and Nonaka, T.
- Organizer
  International Union of Microbiological Societies 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Enzymatic characterization of S46 peptidase from pathogenic bacteria2017
- Author(s)
  Nobuyuki Honma, Yasuhiro Ito, Akihiro Nakamura, Saori Roppongi, Yuki Sakurai, Yoshiyuki Suzuki, Koushi Hidaka, Yuko Tsuda, Yasumitsu Sakamoto, Nobutada Tanaka, Wataru Ogasawara
- Organizer
  2017 1st STI-Gigaku
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Identification of Substrate Recognition Residues in Family S46 Peptidase from Gram-Negative Bacteria2017
- Author(s)
  Nakamura, A., Ito, Y., Suzuki, Y., Roppongi, S., Hidaka, K., Sakamoto, Y., Tanaka, N., and Ogasawara, W.
- Organizer
  6th International GIGAKU conference in Nagaoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Identification of substrate recognition residues in family S46 peptidase from pathogenic non-fermenting gram-negative bacteria.2017
- Author(s)
  Nakamura, A., Ito, Y., Suzuki, Y., Roppongi, S., Hidaka, K., Sakamoto, Y., Tanaka, N., and Ogasawara, W.
- Organizer
  International Union of Microbiological Societies 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Family S46ペプチダーゼの新規基質認識残基の同定2017
- Author(s)
  中村彰宏、伊藤康広、鈴木義之、六本木沙織、飯塚一平、阪本泰光、田中信忠、小笠原渉
- Organizer
  第17回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Analysis of Substrate Recognition Residues in Family S46 Peptidase from Gram-Negative Bacteria2017
- Author(s)
  Nakamura, A., Ito, Y., Suzuki, Y., Roppongi, S., Hidaka, K., Sakamoto, Y., Tanaka, N., and Ogasawara, W.
- Organizer
  2017 2nd STI-Gigaku
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Identification of dipeptidic inhibitors targeting DPP7 derived from multiple drug resistant bacteria Stenotrophomonas maltophilia2017
- Author(s)
  Yuki Sakurai, Koushi Hidaka, Anna Miyazaki, Keiko Hojo, Saori Roppongi, Yasumitsu Sakamoto, Yasuhiro Ito, Yoshiyuki Suzuki, Wataru Ogasawara, Nobutada Tanaka, and Yuko Tsuda
- Organizer
  The 54th Japanese Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] S46 family bacterial dipeptidyl aminopeptidases as novel antibiotics targets.2017
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Ito, Y., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W., and Tanaka, N.
- Organizer
  International Union of Microbiological Societies 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Crystal structure of dipeptidyl amino peptidase 11 from Porphyromonas gingivalis.2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.
- Organizer
  42nd Naito Conference on In the Vanguard of Structural Biology
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Crystal structure of dipeptidyl amino peptidase 11 (DPP11) from periodontal pathogen.2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.
- Organizer
  ISS R&D 2016
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-07-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Crystal Structure analaysis of dipeptidyl peptidase 11 from Porphyromonas gingivalis.2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.
- Organizer
  16th International Conference on the Crystallization of Biological Macromolecules
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2016-07-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Enzymatic characterization of S46 peptidase from pathogenic bacteria.2016
- Author(s)
  Ito, Y., Nakamura, A., Roppongi, S., Sakurai, Y., Suzuki, Y., Hidaka, K., Tsuda, Y., Sakamoto, Y., Tanaka, N. and Ogasawara, W.
- Organizer
  The 5th International GIGAKU Conference in Nagaoka
- Place of Presentation
  Nagaoka, Japan
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Structural Analysis of Dipeptidyl Peptidase 11 (DPP11) from Porphyromonas gingivalis.2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.
- Organizer
  AsCA 2016
- Place of Presentation
  Hanoi, Socialist Republic of Vietnam
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] 歯周病菌由来酸性アミノ酸特異的DPP（ジペプチジルペプチダーゼ）の構造生物学的研究（2016
- Author(s)
  六本木沙織、鈴木義之、飯塚一平、舘岡千佳、藤本真友、伊中浩治、田仲広明、太田和敬、山田貢、合田浩明、野中孝昌、小笠原渉、田中信忠、阪本泰光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] 歯周病菌由来DPP11の構造生物学的研究2016
- Author(s)
  六本木沙織、鈴木義之、飯塚一平、伊中浩治、田仲広明、太田和敬、山田貢、小笠原渉、田中信忠、野中孝昌、阪本泰光
- Organizer
  2015 量子ビームサイエンスフェスタ
- Place of Presentation
  つくば市
- Year and Date
  2016-03-15
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Structure-Function Relationships of S46 Peptidases from Non-Fermenting Gram-Negative Rods.2016
- Author(s)
  Roppongi, S., Suzuki, Y., Iizuka, I., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Nonaka, T., Ogasawara, W., Tanaka, N. and Sakamoto, Y.
- Organizer
  116th The American Society for Microbiology General meeting
- Place of Presentation
  Boston, USA
- Year and Date
  2016-06-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] Structure and Fuctions of Dipeptidyl Peptidase 11 (DPP11) from Porphyromonas gingivalis.2016
- Author(s)
  Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Gouda, H., Nonaka, T., Ogasawara, W. and Tanaka, N.
- Organizer
  2nd International Symposium on Space Science of High Quality Protein Crystallization
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04902
[Presentation] First structure of Family S46 peptidase reveal exo-peptidase activity in Clan PA peptidases2015
- Author(s)
  飯塚一平、阪本泰光、鈴木義之、舘岡千佳、六本木沙織、藤本真友、伊中浩治、田仲広明、正木美佳、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠
- Organizer
  9th General Meeting of The International Proteolysis Society
- Place of Presentation
  ペナン、マレーシア
- Year and Date
  2015-10-05
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Pseudoxanthomonas mexicana WO24由来ジペプチジルアミノペプチダーゼの構造解析2015
- Author(s)
  阪本泰光、鈴木義之、飯塚一平、館岡千佳、六本木沙織、藤本真友、伊中浩治、田中広明、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠
- Organizer
  第135回日本薬学会年会
- Place of Presentation
  デザインクリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Pseudoxanthomonas mexicana WO24 由来DAP BII の構造機能相関2015
- Author(s)
  阪本泰光、鈴木義之、飯塚一平、館岡千佳、六本木沙織、藤本真友、伊中浩治、田中広明、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠
- Organizer
  第3回物構研サイエンスフェスタ
- Place of Presentation
  エポカルつくば（つくば）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Clan PA S46ファミリーに属するDAP BIIの結晶構造解析2015
- Author(s)
  飯塚一平、鈴木義之、館岡千佳、六本木沙織、藤本真友、伊中浩治、田仲広明、太田和敬、岡田宏文、野中孝昌、森川康、中村和郎、小笠原渉、田中信忠、阪本泰光
- Organizer
  第54回日本薬学会東北支部大会
- Place of Presentation
  矢巾町
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Structural and mutational studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis2015
- Author(s)
  阪本泰光、鈴木義之、飯塚一平、舘岡千佳、六本木沙織、藤本真友、伊中浩治、田仲広明、太田和敬、山田貢、合田浩明、野中孝昌、小笠原渉、田中信忠
- Organizer
  9th General Meeting of The International Proteolysis Society
- Place of Presentation
  ペナン、マレーシア
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Clan PA に属するExopeptidase family S46 の構造機能相関の解明2015
- Author(s)
  鈴木義之、阪本泰光、田中信忠、小笠原渉
- Organizer
  日本農芸化学会2015年度年会
- Place of Presentation
  岡山大学津島キャンパス（岡山）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal Structure analyses of dipeptidyl aminopeptidase BII from P. mexicana WO24.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Organizer
  The 23rd Congress and General Assembly of the International Union of Crystallography.
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2014-08-11
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal structure studies of dipeptidyl aminopeptidase BII from Pseudoxanthomonas mexicana WO24.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Organizer
  The 28th Symposium of the Protein Society
- Place of Presentation
  サンディエゴ（米国）
- Year and Date
  2014-07-27
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal structure analysis of dipeptidyl amino peptidase from P. mexicana WO24.2014
- Author(s)
  Roppongi　S, Tateoka C, Suzuki Y, Fujimoto M, Morisawa S, Iizuka I, Ogasawara W, Tanaka N, Sakamoto Y, Nonaka T.
- Organizer
  The 23rd Congress and General Assembly of the International Union of Crystallography.
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Pseudoxanthomonas mexicana WO24 由来 dipeptidyl aminopeptidase 複合体の結晶構造2014
- Author(s)
  六本木沙織、館岡千佳、森澤さおり、飯塚一平、藤本真友、鈴木義之、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  横浜産貿易ホール（横浜）
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Structural basis of exopeptidase activity of a dipeptidyl aminopeptidase BII, a member of the family S46 peptidases.2014
- Author(s)
  Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Nonaka T, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N.
- Organizer
  15th International Conference on the Crystallization of Biological Macromolecules.
- Place of Presentation
  ハンブルグ（ドイツ）
- Year and Date
  2014-09-17
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] Crystal Structures of Dipeptidyl aminopeptidases from Pseudoxanthomonas mexicana WO24.2014
- Author(s)
  Roppongi S, Suzuki Y, Iizuka I, Tateoka C, Fujimoto M, Inaka K, Tanaka H, Masaki M, Ohta K, Okada H, Morikawa Y, Nakamura KT, Ogasawara W, Tanaka N, Sakamoto Y, Nonaka T.
- Organizer
  New York Structural Biology Discussion Group Summer Meeting.
- Place of Presentation
  ニューヨーク（米国）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PROJECT-25462872
[Presentation] 熱帯熱マラリア原虫由来非メバロン酸経路関連酵素に関する構造生物学的研究2012
- Author(s)
  葉梨繁樹、梅田知伸、中西雅之、北出幸夫、田中信忠
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] 抗マラリア薬の開発を目指した構造生物学的研究2012
- Author(s)
  田中信忠、梅田知伸、日下部吉男、中西雅之、北出幸夫、中村和郎
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] 抗マラリア薬の開発を目指した構造生物学的研究2012
- Author(s)
  田中信忠、梅田知伸、日下部吉男、中西雅之、北出幸夫、中村和郎
- Organizer
  日本薬学会(招待講演)
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] Crystal structures of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) from Plasmodium falciparum complexed with inhibitors2012
- Author(s)
  梅田知伸、田中信忠、日下部吉男、中西雅之、北出幸夫、中村和郎
- Organizer
  第11回アジア結晶学会
- Place of Presentation
  アデレード
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] Structural basis of fosmidomycin's action on Plasmodium falciparum2011
- Author(s)
  Tanaka, N., Umeda, T., Kusakabe, Y., Nakanishi, M., Kitade, Y., & Nakamura, K.T.
- Organizer
  XXII congress and general assembly of the International Union of Crystallography
- Place of Presentation
  マドリッド、スペイン
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] 抗マラリア新薬の開発を目指して2011
- Author(s)
  田中　信忠
- Organizer
  未来のバイオ技術勉強会(招待講演)
- Place of Presentation
  高エネルギー加速器研究機構
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] ホスミドマイシン標的酵素の立体構造2011
- Author(s)
  梅田知伸、田中信忠、日下部吉男、中西雅之、北出幸夫、中村和郎
- Organizer
  第28回PFシンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] P. mexicana WO24由来ジペプチジルアミノペプチダーゼの結晶構造解析
- Author(s)
  六本木沙織、館岡千佳、飯塚一平、鈴木義之、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  平成24年度日本結晶学会年会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] Pseudoxanthomonas ｍexicana WO24由来アミノペプチダーゼの結晶構造解析
- Author(s)
  館岡千佳、六本木沙織、森澤さおり、飯塚一平、鈴木義之、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  第1回物構研サイエンスフェスタ
- Place of Presentation
  つくば国際会議場（つくば）
- Data Source
  KAKENHI-PROJECT-23590495
[Presentation] Pseudoxanthomonas mexicana WO24由来ペプチド分解酵素の構造解析
- Author(s)
  館岡千佳、六本木沙織、森澤さおり、飯塚一平、鈴木義之、小笠原渉、田中信忠、阪本泰光、野中孝昌
- Organizer
  日本薬学会第133回年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23590495

1. SAKAMOTO YASUMITSU (00349036)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. 中西雅之 (00281048)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 野中由香莉 (40710520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 日高興士 (30445960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 多部田康一 (20401763)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NUKAGA Michiyoshi (20251150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OHUCHI Nozomi (20398556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HOSHINO Chuji (90257220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OGASAWARA Wataru (40292172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
10. Endo Satoshi (60433207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TOYOOKA Naoki (10217565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GODA Hiroaki (60276160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUWATA Kazuo (00170142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中村和郎 (00012675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 北出幸夫 (20137061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. BONOMO Robert

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SEKIYA Mizuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 藤井勲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Nobutada 田中 信忠

TANAKA Nobutada 田中 信忠

田中 信忠 タナカ ノブタダ

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Development of allosteric chaperone compounds based on structural information of the target enzymesPrincipal Investigator

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Development of a novel inhibitor cocktail targeting peptidases from sugar non-fermentative bacteriaPrincipal Investigator

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Development of novel antibiotics targeting peptidases of non-fermenting gram negative rods.Principal Investigator

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Structure-activity relationship studies of the enzymes belonging to the non-mevalonate pathway of Plasmodium falciparumPrincipal Investigator

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インターフェロン誘導型抗ウイルス機構2-5Aシステムにおける機能制御の構造的基盤Principal Investigator

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細胞運動刺激因子の立体構造に基づく腫瘍転移抑制剤の開発Principal Investigator

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抗マラリア薬の開発を志向したマラリア原虫由来加水分解酵素の基質認識機構の解明Principal Investigator

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がん細胞運動刺激因子AMFとATXの立体構造と機能Principal Investigator

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Tanaka Nobutada 田中信忠

TANAKA Nobutada 田中信忠

田中信忠タナカノブタダ