KAWAKAMI Kazuyuki 川上和之

Researcher Number	00293358
Other IDs
Affiliation *help	2013 – 2015 : 東京女子医科大学, 医学部, 准教授 2011 – 2013 : 金沢大学, がん進展制御研究所, 准教授 2007 – 2011 : 金沢大学, がん研究所, 准教授 2008 – 2009 : 金沢大, がん研究所, 准教授 2007 : 金沢大, がん研究所, 助教授 … More
Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / Digestive surgery / Thoracic surgery / General surgery / Medical systems
Keywords	Principal Investigator DNAメチル化 / loss of heterozygosity / 大腸癌 / gene polymorphism / LINE-1 / methylator phenotype / gamma-glutamyl hydrolase / 血液検査 / 化学療法 / Thymidvlate synthase … More Except Principal Investigator 大腸がん / GSK3β / DNAメチル化 / 大腸癌 / 抗がん剤 / 消化器がん / 遺伝子多形性 / loss of heterozygosity / TAE / allelic loss / thymidylate synthase / チミジル酸合成酵素 / polymerase chain reaction / gene polymorphism / メチル化 / cisplatin / complementary DNA / 相補的逆配列 / 癌化学療法 / biochemical modulation / lung cancer / complementary repeat sequence / メチオニン / Drug repositioning / 標的治療 / リピート構造 / 遺伝子多型 / inhibition / 能動輸送 / フッ化ピリミジン / high frequency power source / molecular oncology / β-TrCP / neutral amino acid / 遺伝子診断 / heating for deep-seated cancer / 医薬品 / reduced folate / ガン治療 / 5フロロウラシル / ナノバイオ / 細胞増殖 / 薬剤スクリーニング / 磁気分離 / methionine / colorectal cancer / 塞栓療法 / 医用機器 / chromosome 18 / β-カラニン / 分子特性 / 5-FU / 高周波電源 / 試験管内翻訳アッセイ / amino acid transporter / すい臓がん / 動物実験 / 分子生物学 / active transport / microsatellite marker / β-カテニン / induction heating / DNA methylation / DM / 遺伝子クローニング / 第18番染色体 / microsatellite marler / VX-2 / GSK3beta / 治療 / レトロポゾン / 深部加温 / Wnt / cell line / 葉酸 / CRD-BP / nano bio / シグナル伝達 / 翻訳活性 / 蛋白翻訳活性 / 翻訳後調節 / 細胞運動 / β-catenin / 診断 / 繰り返し配列 / 癌抑制遺伝子 / LINE-1 / 感受性予測因子 / 癌治療 / chemosensitivity predictor / Embolism medical treatment / 5-fluorouracil / スプラチン / dTHd uptake / 胃癌 / 試験管内転写アッセイ / translational activity / cancer treatment / エネルギー代謝 / 癌 / 細胞特性 / 分子標的 / medical device / 肺癌 / posttranscriptional regulation / loss of heterogeneity / tandem repeat sequence / 誘導加温 / 非翻訳領域 Less

レトロポゾンの制御によるがん治療開発Principal InvestigatorOngoing
- Principal Investigator
  
  川上和之
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Molecular analysis of colorectal cancer with LINE-1 hypomethylation and its application to cancer diagnosis and therapyPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI KAZUYUKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
  Kanazawa University
Therapeutic effect of the GSK3beta-inhibiting drugs against gastrointestinal cancer and the elucidation of a molecular mechanism
- Principal Investigator
  
  HIROSE Mayumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Treatment of gastrointestinal cancer by targeting the distinct energy metabolism of cancer cells
- Principal Investigator
  
  MINAMOTO Toshinari
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Molecular basis of aberrant cellular pathways in gastrointestinal cancer and its application to diagnosis and treatment
- Principal Investigator
  
  MINAMOTO Toshinari
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
GSK3βのがん促進機能の分子機構解明とその阻害に基づく消化器がん治療法の開発
- Principal Investigator
  
  源利成
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
Mechanistic analysis on DNA methylation in colorectal cancer and its application to diagnosis and therapyPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Kazuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Molecular basis of deregulated Wnt signaling in clinical colorectal cancer
- Principal Investigator
  
  MINAMOTO Toshinari
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Genetic and epigenetic analyses of folate and nudeotide metabolizing enzymes in gastrointestinal cancerPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Kazuyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Development of Cancer Treatment System by Induction heating
- Principal Investigator
  
  NAGANO Isamu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical systems
- Research Institution
  Kanazawa University
Molecular characterization of lung cancer by DNA methylation profilePrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Kazuyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kanazawa University
Investigation of the significance of the loss of 18p which is frequently observed in colorectal cancer tissue.
- Principal Investigator
  
  OMURA Kenji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KANAZAWA UNIVERSITY
末梢血中遊離DNAのエピジエネティクスを標的とした癌分子診断Principal Investigator
- Principal Investigator
  
  川上和之
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Research Institution
  Kanazawa University
Polymorphism of thymidylate synthase gene in human gastrointestinal carcinoma cells and its regulational role in protein expression
- Principal Investigator
  
  OMURA Kenji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
CDDP耐性細胞の細胞膜メチオニン能動輸送に及ぼすcDDPの影響-cDDPの細胞内分布と葉酸代謝修飾の定量的評価-
- Principal Investigator
  
  大村健二
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kanazawa University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004

All Journal Article Presentation Book

[Book] Colorectal Cancer Biology-From genes to Tumor2012
- Author(s)
  Minamoto T, et al., Kawakami K
- Publisher
  nTech Open Access Company
- Data Source
  KAKENHI-PROJECT-23591955
[Book] Colorectal Cancer Biology -From Genes to Tumor2012
- Author(s)
  Minamoto T, et al, Kawakami K
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-22249051
[Book] Distinct pathologic role for glycogen synthase kinase 3β in colorectal cancer progression2012
- Author(s)
  Minamoto T, Kotake M, Nakada M, Shimasaki T, Motoo Y, Kawakami K
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23659643
[Book] RNA Technologies and Their Applications ; Erdmann VA, Barciszewski J, eds. RNAi in malignant brain tumors : relevance to molecular and translational research,分担執筆2011
- Author(s)
  Nakada M, Kawakami K, et al, Minamoto T
- Publisher
  Springer Verlag
- Data Source
  KAKENHI-PROJECT-22249051
[Book] RNA Technologies and Their Applications2010
- Author(s)
  Nakada M, Kawakami K, et al, Minamoto T
- Publisher
  Springer Verlag
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Importance of Central Retinal Sensitivity for Prediction of Visual Acuity after Intravitreal Bevacizumb in Eyes with Macular Edema Associated with Branch Retinal Vein Occlusion2016
- Author(s)
  Sugimoto M, Ichio A, Kondo M
- Journal Title
  
  PLoS One
  
  Volume : 10 Pages : 1-1
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462683, KAKENHI-PROJECT-15H04994, KAKENHI-PROJECT-26293436, KAKENHI-PROJECT-25450059, KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-15K09761, KAKENHI-PROJECT-15K10839, KAKENHI-PROJECT-26460856, KAKENHI-PROJECT-26462657, KAKENHI-PROJECT-26462675, KAKENHI-PUBLICLY-15H01119, KAKENHI-PROJECT-25461642, KAKENHI-PROJECT-25505001, KAKENHI-PROJECT-25861511, KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-25515009, KAKENHI-PROJECT-23390078, KAKENHI-PROJECT-23590814, KAKENHI-PROJECT-23591937, KAKENHI-PROJECT-23592041, KAKENHI-PROJECT-23592747, KAKENHI-PROJECT-24390456, KAKENHI-PROJECT-24700529, KAKENHI-PROJECT-25290077, KAKENHI-PROJECT-25430054, KAKENHI-PROJECT-25640044, KAKENHI-PROJECT-25670163, KAKENHI-PROJECT-26460314, KAKENHI-PROJECT-26461240, KAKENHI-PROJECT-26115006, KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22249051, KAKENHI-ORGANIZER-23110001, KAKENHI-PLANNED-23110002, KAKENHI-PROJECT-23591504, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592142, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-24592257, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-25860640, KAKENHI-PROJECT-12J07421, KAKENHI-PROJECT-21390489, KAKENHI-PROJECT-21570167, KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-23590949, KAKENHI-PROJECT-23591254, KAKENHI-PLANNED-20119006, KAKENHI-PROJECT-21300157, KAKENHI-PROJECT-23500465, KAKENHI-PROJECT-23592751, KAKENHI-PLANNED-21113002, KAKENHI-PROJECT-21570021
[Journal Article] 消化器がん化学療法の最先端：大腸癌2014
- Author(s)
  川上和之、林　和彦
- Journal Title
  
  医学と薬学
  
  Volume : 71 Pages : 340-343
- Data Source
  KAKENHI-PROJECT-26462028
[Journal Article] Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling2013
- Author(s)
  Pyko IV, Nakada M, Sabit H, Teng L, Furuyama N, Hayashi Y, Kawakami K, Minamoto T, Fedulau AS, Hamada J
- Journal Title
  
  Carcinogenesis
  
  Volume : 34 Pages : 2206-2217
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Year and Date
  2013-09-26
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-25670572
[Journal Article] Aberrant Glycogen Synthase Kinase 3β Is Involved in Pancreatic Cancer Cell Invasion and Resistance to Therapy2013
- Author(s)
  Kitano A
- Journal Title
  
  PLoS ONE
  
  Volume : 8 Issue : 2 Pages : e55289
- Publisher
  PLoS ONE
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Year and Date
  2013-02-08
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-22790542, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23590356, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-25460793, KAKENHI-PROJECT-25670572
[Journal Article] Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?2013
- Author(s)
  Loh M, Chua D, Yao Y, Soo RA, Garrett K, Zeps N, Platell C, Minamoto T, Kawakami K, Iacopetta B, Soong R
- Journal Title
  
  Pharmacogenomics J
  
  Volume : 13 Pages : 423-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-25670572, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling2013
- Author(s)
  Pyko IV, Nakada M, Sabit H, Teng L, Furuyama N, Hayashi Y, Kawakami K, Minamoto T, Fedulau AS, Hamada J
- Journal Title
  
  Carcinogenesis
  
  Volume : 34 Pages : 2206-2217
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Year and Date
  2013-09-26
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-25670572
[Journal Article] Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?2013
- Author(s)
  Loh M, Chua D, Yao Y, Soo RA, Garrett K, Zeps N, Platell C, Minamoto T, Kawakami K, Iacopetta B, Soong R
- Journal Title
  
  Pharmacogenomics J
  
  Volume : 13 Pages : 423-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-25670572, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?2013
- Author(s)
  Loh M, Chua D, Yao Y, Soo RA, Garrett K, Zeps N, Platell C, Minamoto T, Kawakami K, Iacopetta B, Soong R
- Journal Title
  
  Pharmacogenomics J
  
  Volume : 13 Pages : 423-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-25670572, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine2012
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et al
- Journal Title
  
  J Gastroenterol
  
  Volume : 47 (3) Pages : 321-33
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] LINE-1 methylation shows little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
- Author(s)
  Matsunoki A, Kawakami K, et al, Minamoto T
- Journal Title
  
  BMC Cancer
  
  Volume : 12 Pages : 574-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene2012
- Author(s)
  Mimura M, Kawakami K, Ohno H, Minamoto T, et al
- Journal Title
  
  Int J - 5 -Cancer
  
  Volume : 130 (5) Pages : 1011-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23659643, KAKENHI-PLANNED-20113003
[Journal Article] Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine2012
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et al
- Journal Title
  
  J Gastroenterol
  
  Volume : 47 (3) Pages : 321-33
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] LINE-1 methylation shows little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
- Author(s)
  Matsunoki A, Kawakami K, et al, Minamoto T
- Journal Title
  
  BMC Cancer
  
  Volume : 12 Pages : 574-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine2012
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et al
- Journal Title
  
  J Gastroenterol
  
  Volume : 47 (3) Pages : 321-33
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene2012
- Author(s)
  Mimura M, Kawakami K, Ohno H, Minamoto T, et al
- Journal Title
  
  Int J - 5 -Cancer
  
  Volume : 130 (5) Pages : 1011-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23659643, KAKENHI-PLANNED-20113003
[Journal Article] LINE-1 methylation shows little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
- Author(s)
  Matsunoki A, Kawakami K, et al, Minamoto T
- Journal Title
  
  BMC Cancer
  
  Volume : 12 Pages : 574-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Loss of HITS (FAM107B) expression in cancers of multiple organs : tissue microarray analysis2012
- Author(s)
  Nakajima H, Koizumi K, Tanaka T, Ishigaki Y, Yoshitake Y, Yonekura H, Sakuma T, Fukushima T, Umehara H, Ueno S, Minamoto T and Motoo Y
- Journal Title
  
  International Journal of Oncology
  
  Volume : 41 Pages : 1347-1357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590898, KAKENHI-PROJECT-23792017, KAKENHI-PROJECT-21590389, KAKENHI-PROJECT-22249051
[Journal Article] Metabolic disorder, inflammation, and deregulated molecular pathways converging in pancreatic cancer development: Implications for new therapeutic strategies2011
- Author(s)
  Motoo Y, et al, Minamoto T
- Journal Title
  
  Cancers
  
  Volume : 3 Issue : 1 Pages : 446-460
- Publisher
  MDPI Publishing
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Long interspersed nuclear element-1 hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CpG island methylator phenotype-negative colorectal cancer.2011
- Author(s)
  Kawakami K, (他4名), Minamoto T.
- Journal Title
  
  Cancer Sci 102
  
  Pages : 166-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Long interspersed nuclear element-I hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CnG island methvlator phenotype-negative colorectal cancer2011
- Author(s)
  Kawakami_K, et al, Minamoto T
- Journal Title
  
  Cancer Science
  
  Volume : 102 Pages : 166-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFFI epigenetic silencing2011
- Author(s)
  Tomita H, Kawakami K, Minamoto T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume : 140 Pages : 879-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Long interspersed nuclear element-1 hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CpG island methylator phenotype-negative colorectal cancer2011
- Author(s)
  Kawakami K, et al, Minamoto T
- Journal Title
  
  Cancer Science
  
  Volume : 102 Issue : 1 Pages : 166-174
- Publisher
  Japanese Cancer Association = 日本癌学会
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23659643
[Journal Article] Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing.2011
- Author(s)
  Tomita H, Kawakami K, Minamoto T, et al
- Journal Title
  
  Gastroenterology
  
  Volume : 140 (3) Pages : 879-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23590919, KAKENHI-PROJECT-23659643
[Journal Article] Long interspersed nuclear element-1 hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CpG island methylator phenotype-negative colorectal cancer2011
- Author(s)
  Kawakami K, et al, Minamoto T
- Journal Title
  
  Cancer Science
  
  Volume : (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing2011
- Author(s)
  Tomita H, Kawakami K, Minamoto T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume : (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Metabolic disorder, inflammation and deregulated molecular pathways converging in pancreatic cancer development : implications for new therapeutic strategies2011
- Author(s)
  Motoo Y, et al, Kawakami K, Minamoto T
- Journal Title
  
  Cancers
  
  Volume : (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Metabolic disorder, inflammation, and deregulated molecular pathways converging in pancreatic cancer development: Implications for new therapeutic strategies2011
- Author(s)
  Motoo Y, et al, Minamoto T
- Journal Title
  
  Cancers
  
  Volume : 3 Issue : 1 Pages : 446-460
- Publisher
  MDPI Publishing
- URL
  http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643
[Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans2010
- Author(s)
  Peterson AJ, Kawakami K, Minamoto T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume : 139 Pages : 2005-2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation.2010
- Author(s)
  Nakajima H, Kawakami K, et al, Minamoto T
- Journal Title
  
  International Journal of Oncology
  
  Volume : 37 Pages : 583-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Long interspersed nuclear element I hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer2010
- Author(s)
  Saito K, Kawakami K, et al, Minamoto T
- Journal Title
  
  Clinical Cancer Research
  
  Volume : 16 Pages : 2418-2426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer.2010
- Author(s)
  Saito K, Kawakami K (他3名), Minamoto T.
- Journal Title
  
  Clin Cancer Res 16
  
  Pages : 2418-2426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.2010
- Author(s)
  Peterson AJ, Kawakami K, Minamoto T, (他8名).
- Journal Title
  
  Gastroenterology 139
  
  Pages : 2005-2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Induction of HITS, a newly identified family with sequence similarity 107 protein(FAM107B), in cancer cells by heat shock stimulation.2010
- Author(s)
  Nakajima H, Kawakami K, et al, Minamoto T
- Journal Title
  
  International Journal of Oncology
  
  Volume : 37 Pages : 583-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage lA non-small cell lung cancer2010
- Author(s)
  Saito K, Kawakami K, et al, Minamoto T
- Journal Title
  
  Clinical Cancer Research
  
  Volume : 16 Pages : 2418-2426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans2010
- Author(s)
  Peterson AJ, Kawakami K, Minamoto T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume : 139 Pages : 2005-2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans2010
- Author(s)
  Peterson AJ, Kawakami K, Minamoto T, et al
- Journal Title
  
  Gastroenterology
  
  Volume : 139 (6) Pages : 2005-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer2010
- Author(s)
  Saito K, Kawakami K, et al, Minamoto T
- Journal Title
  
  Clinical Cancer Research
  
  Volume : 16 Issue : 8 Pages : 2418-2426
- Publisher
  American Association for Cancer Research
- Year and Date
  2010-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] RNAi in malignant brain tumors : relevance to molecular and translational research.2010
- Author(s)
  Nakada M, Kawakami K, et al., Minamoto T.
- Journal Title
  
  Erdmann VA, Barciszewski J, eds., RNA Technologies and Their Applications, Springer Verlag (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] LINE-1 hypomethylation is a poor prognostic factor in stage IA non-small cell lung cancer.2010
- Author(s)
  Saito K, Kawakami K, et al., Minamoto T.
- Journal Title
  
  Clinical Cancer Research (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.2009
- Author(s)
  Jin MJ, Kawakami K, (他6名), Minamoto T.
- Journal Title
  
  Cancer Sci 100
  
  Pages : 2325-2330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2009
- Author(s)
  Miyashita K, Kawakami K, et al
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages : 887-897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels2009
- Author(s)
  Jin MJ, Kawakami K, Minamoto T, et al
- Journal Title
  
  Cancer Science 100
  
  Pages : 2325-2330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA2009
- Author(s)
  Noubissi FK, Kawakami K, Minamoto T, et al
- Journal Title
  
  Cancer Research 69
  
  Pages : 8572-8578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Deregulated glycogen synthase kinase 3β sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.2009
- Author(s)
  Mai W, Kawakami K, (他7名), Minamoto T.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages : 6810-6819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Deregulated glycogen synthase kinase 3β sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase2009
- Author(s)
  Mai W, Kawakami K, Minamoto T, et al
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages : 6810-6819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3β2009
- Author(s)
  Miyashita K, Kawakami K, Minamoto T, et al
- Journal Title
  
  Anti-Cancer Agents Med Chem 9
  
  Pages : 1114-1122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2009
- Author(s)
  Miyashita K, Kawakami K, Nakada M, Mai W, Shakoori A, Shakoori A, Hayashi Y, Hamada J, Minamoto T.
- Journal Title
  
  Clin Cancer Res 15(3)
  
  Pages : 887-897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Potential therapeutic effect of glycogen synthase kinase 3βinhibition against human glioblastoma.2009
- Author(s)
  Miyashita K, Kawakami K, etal, Minamoto T
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages : 887-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2009
- Author(s)
  Miyashita K, Kawakami K, et.al, Minamoto T
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages : 887-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Deregulated glycogen synthase kinase 3β sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.2009
- Author(s)
  Mai W, Kawakami K, Shimasaki T, et al., Minamoto T.
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages : 6810-6819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.2009
- Author(s)
  Jin MJ, Kawakami K, et al., Minamoto T.
- Journal Title
  
  Cancer Science 100
  
  Pages : 2325-2330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3β.2009
- Author(s)
  Miyashita K, Shimasaki T, et al., Kawakami K, Minamoto T.
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry 9
  
  Pages : 1114-1122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Reduced perioperative immune response in video-assisted versus open surgery in a rat model.2009
- Author(s)
  Ito Y, Kawakami K, et al.
- Journal Title
  
  Surgery Today 39
  
  Pages : 682-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GUI1 mRNA.2009
- Author(s)
  Noubissi FK, Kawakami K, Minamoto T, et al.
- Journal Title
  
  Cancer Research 69
  
  Pages : 8572-8578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition againsthuman glioblastoma.2009
- Author(s)
  Miyashita K, Kawakami K, et al., Minamoto T.
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages : 887-897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Low expression of gamma glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.2008
- Author(s)
  Kawakami K, et. al.
- Journal Title
  
  British Journal of Cancer (印刷中)(掲載確定)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients : is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?2008
- Author(s)
  Iacopetta B, Kawakami K, Watanabe T.
- Journal Title
  
  Int J Clin Oncol 13
  
  Pages : 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Predicting clinical outcome of 5-fluorouracil- based chemotherapy for colon cancer patients : is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?2008
- Author(s)
  Iacopetta B, Kawakami K, et al
- Journal Title
  
  International Journal of Clinical Oncology 13
  
  Pages : 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Low expression of γ -glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.2008
- Author(s)
  Kawakami K, (他7名), Minamoto T.
- Journal Title
  
  Br J Cancer 98
  
  Pages : 1555-1561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Low expression of γ-glutamyl hydrolase mRNA in primarycolorectal cancer with the CpG island methylator phenotype2008
- Author(s)
  Kawakami K, Minamoto T, et al
- Journal Title
  
  British Journal of Cancer 98
  
  Pages : 1555-1561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390353
[Journal Article] Low expression of gamma glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype2008
- Author(s)
  Kawakami K, et. al.
- Journal Title
  
  British Journal of Cancer (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Predicting clinical outcome of 5-fluorouracilbased chemotherapy for colon cancer patients : is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?2008
- Author(s)
  Iacopetta B, Kawakami K, Watanabe T.
- Journal Title
  
  Int J Clin Oncol 13(6)
  
  Pages : 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Low expression of γ-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype2008
- Author(s)
  Kawakami K, Ooyama A, Ruszkiewicz A, Jin M, Watanabe G, Moore J, Oka T, Iacopetta B, Minamoto T.
- Journal Title
  
  Br J Cancer 98(9)
  
  Pages : 1555-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Low expression of gamma glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype2008
- Author(s)
  Kawakami, K., et. al.
- Journal Title
  
  British Journal of Cancer
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Wnt/β-カテニンシグナル制御破綻の新しい分子メカニズムー大腸がん医療との関連-2008
- Author(s)
  山下要, 川上和之, 源利成
- Journal Title
  
  Biotherapy 22
  
  Pages : 287-95
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] 大腸がんの診断と検診を目指す便の細胞・分子マーカー検出の試み.2008
- Author(s)
  源利成, ほか, 川上和之
- Journal Title
  
  臨床消化器内科 23
  
  Pages : 183-89
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Low expression of γ-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.2008
- Author(s)
  Kawakami K., et al, Minamoto T
- Journal Title
  
  British Journal of Cancer 98
  
  Pages : 1555-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients : is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?2008
- Author(s)
  Iacopetta B, Kawakami K, et al.
- Journal Title
  
  International Journal of Clinical Oncology 13
  
  Pages : 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Low expression of gamma glutamyl hydrolase mRNA in primary colorectalcancer with the CpG island methylator phenotype2008
- Author(s)
  Kawakami K, et. al., Mlnamoto T.
- Journal Title
  
  British Joumal of Cancer (印刷中)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Low expression of y-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype2008
- Author(s)
  Kawakami K., et.al., Minamoto T
- Journal Title
  
  British Journal of Cancer 98
  
  Pages : 1555-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients : is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?2008
- Author(s)
  Iacopetta B, Kawakami K, et.al.
- Journal Title
  
  International Journal of Clinical Oncology 13
  
  Pages : 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] 大腸がんの診断と検診を目指す便の細胞・分子マーカー検出の試み2008
- Author(s)
  源利成, ほか, 川上和之
- Journal Title
  
  臨床消化器内科 23
  
  Pages : 183-89
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Wnt/β-カテニンシグナル制御破綻の新しい分子メカニズム-大腸がん医療との関連-2008
- Author(s)
  山下要, 川上和之, 源利成
- Journal Title
  
  Biothelapy 22
  
  Pages : 287-95
- Data Source
  KAKENHI-PROJECT-20015018
[Journal Article] Detection of epidermal growth factor receptor variations by partially denaturing HPLC.2007
- Author(s)
  Chin TM, et. al., Kawakami K.
- Journal Title
  
  Clinical Chemistry 53
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents.2007
- Author(s)
  Shakoori A, et. al., Kawakami K.
- Journal Title
  
  Cancer Science 98
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa.2007
- Author(s)
  Iacopetta B, et. al., Kawakami K.
- Journal Title
  
  Cancer Science 98
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa2007
- Author(s)
  Iacopetta B, et. al., Kawakami K.
- Journal Title
  
  Cancer Science 98
  
  Pages : 1454-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Shakoori A, et. al., Kawakami K.
- Journal Title
  
  Cancer Science 98
  
  Pages : 1388-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Detection of epidermal growth factor receptor variations by partially denatuning HPLC2007
- Author(s)
  Chin TM, et. al., Kawakami K.
- Journal Title
  
  Clinical Chemistry 53
  
  Pages : 62-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylation levels of LINE-1 repeats and CpG island loci are are inversely related in normal colonic mucosa2007
- Author(s)
  Iacopetta B, Grieu F, Phillips M, Ruszkiewicz A, Moore J, Minamoto T, Kawakami K.
- Journal Title
  
  Cancer Sci 98(9)
  
  Pages : 1454-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K, Minamoto T.
- Journal Title
  
  Cancer Sci 98(9)
  
  Pages : 1388-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Inhibition of GSK-3B activity attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Shakoori, A., et. al., Kawakami, K
- Journal Title
  
  Cancer Science 98
  
  Pages : 1388-1393
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa2007
- Author(s)
  Iacopetta, B., et. al., Kawakami, K
- Journal Title
  
  Cancer Science 98
  
  Pages : 1454-1460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Detection of epidermal growth factor receptor variations by partially denaturing HPLC2007
- Author(s)
  Chin, TM., et. al., Kawakami, K
- Journal Title
  
  Clinical Chemistry 53
  
  Pages : 62-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancercells in rodents2007
- Author(s)
  Shakoori A, et. al., Takahashi Y, Kawakami K, Minamoto T.
- Journal Title
  
  Cancer Science 98
  
  Pages : 1388-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Detection ofactive fraction of GSK3β in cancer cells by nonradioisotopic in vitro kinase assay2007
- Author(s)
  Mai W, et. al., Takahashi Y, Kawakami K. Minamoto T.
- Journal Title
  
  Oncology(註:2007年7月に掲載) 71
  
  Pages : 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Methylation levels of LINE-l repeats and CpG island loci are inversely relatedin normal colnic mucosa2007
- Author(s)
  Iacopetta B, et. al., Minamoto T, Kawakami K
- Journal Title
  
  Cancer Science 98
  
  Pages : 1454-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay.2007
- Author(s)
  Mai W, Takahashi Y, Kawakami K, Minamoto T
- Journal Title
  
  Oncology (印刷中)
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer2006
- Author(s)
  Iacopetta B, et. al., Kawakami K.
- Journal Title
  
  International Journal of Cancer 119
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy2006
- Author(s)
  Ruzzo A, et. al., Kawakami K.
- Journal Title
  
  Journal of Clinical Oncology 24
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  Kawakami K, et. al.
- Journal Title
  
  British Journal of Cancer 94
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population2006
- Author(s)
  Graziano F, Kawakami K, et. al.
- Journal Title
  
  International Journal of Cancer 118
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Detection of active fraction of GSK3β in cancer cells by nonradioisotopic in vitro kinase assay2006
- Author(s)
  Mai W, Miyashita K, Shakoori A, Zhang B, Yu ZW, Takahashi Y, Motoo Y, Kawakami K, Minamoto T.
- Journal Title
  
  Oncology 71(3-4)
  
  Pages : 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy2006
- Author(s)
  Ruzzo, A., et. al., Kawakami, K
- Journal Title
  
  Journal of Clinical Oncology 24
  
  Pages : 1883-1891
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population2006
- Author(s)
  Graziano, F., Kawakami, K., et. al.
- Journal Title
  
  International Journal of Cancer 118
  
  Pages : 628-632
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer2006
- Author(s)
  Iacopetta, B., et. al., Kawakami, K
- Journal Title
  
  International Journal of Cancer 119
  
  Pages : 2272-2278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  Kazuyuki Kawakami
- Journal Title
  
  British Journal of Cancer 94・4
  
  Pages : 593-598
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  Kawakami, K., et. al.
- Journal Title
  
  British Journal of Cancer 94
  
  Pages : 593-598
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Journal Article] Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population.2006
- Author(s)
  Graziano F, Kawakami K, et al.
- Journal Title
  
  International Journal of Cancer 118・3
  
  Pages : 628-632
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] BRAF mutations are associated with distinctive clinical, pathological and moleclar features of colorectal cancer independently of microsatellite instability status.2006
- Author(s)
  Li WQ, Kawakami K, et al.
- Journal Title
  
  Molecular Cancer 5
  
  Pages : 2-2
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] In vitro sensitivity to platinum-derived drugs is associated with expression of thymidylate synthase and dihydropyrimidine dehydrogenase in human lung cancer.2006
- Author(s)
  Takizawa M, Kawakami K, et al.
- Journal Title
  
  Oncology Report 15・6
  
  Pages : 1533-1539
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer.2006
- Author(s)
  Iacopetta B, et al., Kawakami K
- Journal Title
  
  International Journal of Cancer 119・10
  
  Pages : 2272-8
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Prognostic significance of the p16INK4a hypermethylation in non-small cell lung cancer is evident by quantitative DNA methylation analysis.2006
- Author(s)
  Ota N, Kawakami K, et al.
- Journal Title
  
  Anticancer Research 26・5B
  
  Pages : 3729-32
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy.2006
- Author(s)
  Ruzzo A, Kawakami K, et al.
- Journal Title
  
  Journal of Clinical Oncology 24・12
  
  Pages : 1883-1891
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer.2006
- Author(s)
  Kawakami K, et al.
- Journal Title
  
  British Journal of Cancer 94・4
  
  Pages : 593-8
- Data Source
  KAKENHI-PROJECT-18390363
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  K. Kawakami, et. al.
- Journal Title
  
  British Journal of Cancer vol.94
  
  Pages : 593-598
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200034
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  K.Kawakami et al.
- Journal Title
  
  Br J Cancer 94
  
  Pages : 593-598
- Data Source
  KAKENHI-PROJECT-17200034
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  K. Kawakami, et. al.
- Journal Title
  
  Br J Cancer 94
  
  Pages : 593-598
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200034
[Journal Article] DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer2006
- Author(s)
  K.Kawakami, et al.
- Journal Title
  
  Br J Cancer 94
  
  Pages : 593-598
- Data Source
  KAKENHI-PROJECT-17200034
[Journal Article] Thymidylate synthase gene in pharmacogenetics.2004
- Author(s)
  Kazuyuki Kawakami
- Journal Title
  
  Current pharmacogenomics 2
  
  Pages : 137-147
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591386
[Journal Article] Thymidylate synthase gene in pharmacogenetics2004
- Author(s)
  Kazuyuki Kawakami
- Journal Title
  
  Current pharmacogenomics 2
  
  Pages : 137-147
- Data Source
  KAKENHI-PROJECT-16591386
[Presentation] 1細胞単離した循環がん細胞における遺伝子変異解析2015
- Author(s)
  近藤侑鈴、川上和之、ほか
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26462028
[Presentation] Isolation and molecular profiling of a circulating tumor cell by using a novel single cell picking system2013
- Author(s)
  Kondo Y, Kawakami K, et al.
- Organizer
  9th International Symposium on Minimal Residual Cancer
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] Isolation and molecular profiling of a circulating tumor cell by using a novel single cell picking system2013
- Author(s)
  Kondo Y, Hayashi H, Watabe T, Miwa Y, Kinoshita S, Higashimoto H, Sugisaki H, Nakajima G, Kawakami K, Hayashi K, Yamamoto M
- Organizer
  9th International Symposium on Minimal Residual Cancer
- Place of Presentation
  Pullman Paris Bercy (France)
- Year and Date
  2013-09-25
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] Therapeutic effect of GSK3β inhibition by drugs in clinical use against colon and pancreatic cancer2013
- Author(s)
  Mayumi Hirose, Takahiro Domoto, Yumi Ito, Kazuyuki Kawakami, Toshinari Minamoto:
- Organizer
  第３回発がんスパイラル国際シンポジウム　＆　金沢国際がん生物学シンポジウム
- Place of Presentation
  石川県（金沢エクセルホテル東急）
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] GSK3βを標的とした既存医薬品を用いた大腸がん治療の開発2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、伊藤有美、川上和之、源利成
- Organizer
  第 78 回大腸癌研究会
- Place of Presentation
  東京都（都市センターホテル）
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] SK3betaを標的とした既存医薬品を用いた大腸がん治療の開発2013
- Author(s)
  廣瀬まゆみ、堂本貴寛、伊藤有美、川上和之、源利成
- Organizer
  第78回大腸癌研究会
- Place of Presentation
  東京・都市センターホテル
- Year and Date
  2013-01-18
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
- Author(s)
  Matsunoki A, Kawakami K, et al.
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, U.S.A.
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] LINE-1 methylation level is a potential marker of the sensitivity to 5-FU plus oxaliplatin in colorectal cancer cells2012
- Author(s)
  Kaneko M, Kawakami K, et al.
- Organizer
  71st Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
- Author(s)
  Matsunoki A, Kawakami K, Kotake M, Kaneko M, Watanabe G, Minamoto T
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  McCormick Place in Chicago (USA)
- Year and Date
  2012-04-02
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
- Author(s)
  Kawakami K, Matsunoki A, Kotake M, Kaneko M, Kitamura H, Watanabe G, Minamoto T
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Centre Convencions International Barcelona, Spain
- Year and Date
  2012-07-08
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] LINE-1 methylation level is a potential marker of the sensitivity to 5-FU plus oxaliplatin in colorectal cancer cells2012
- Author(s)
  Kaneko M, Kawakami K, Kotake M, Kitamura H, Watanabe G, Minamoto T
- Organizer
  71st Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  ホテルロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
- Author(s)
  Kawakami K, et al.
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
- Author(s)
  Matsunoki A. Kawakami K. Kotake M. Kaneko M. Watanabe G. Minamoto T
- Organizer
  103th Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Illinois, U.S.A. (McCormick Place)
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell.2012
- Author(s)
  Kawakami K, Matsunoki A, Kotake M, kaneko M, Kitamura H, Watanabe G, Minamoto T
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Barcelona, Spain (Center Conventions International Barcelona)
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase.2012
- Author(s)
  Minamoto T, Mai W, Kyo S, Shakoori A, Miyashita K, Yokoi K, Shimasaki T, Motoo Y, Kawakami K.
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  McCormick Place, Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer.2012
- Author(s)
  Matsunoki A, Kawakami K, Kotake M, KanekoM, Watanabe G, Minamoto T.
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  McCormick Place, Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell.2012
- Author(s)
  Kawakami K, Matsunoki A, Kotake M, KanekoM, Kitamura H, Watanabe G, Minamoto T.
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Centre Convencions International Barcelona, Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
- Author(s)
  Kawakami K
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Centre Convencions International Barcelona )Spain)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase2012
- Author(s)
  Minamoto T, Mai W, Kyo S, Shakoori A, Miyashita K, Yokoi K, Shimasaki T, Motoo Y, Kawakami K
- Organizer
  103rdAnnual Meeting of American Association for Cancer Research
- Place of Presentation
  McCormick Place, Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
- Author(s)
  Kawakami K, Matsunoki A, Kotake M, Kaneko M, Kitamura H, Watanabe G, Minamoto T
- Organizer
  22ndBiennial Congress of the European Association for Cancer Research
- Place of Presentation
  Centre Convencions International Barcelona, Barcelona, Spain
- Year and Date
  2012-07-10
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer.2012
- Author(s)
  Matsunoki A, Kawakami K, Kotake M, KanekoM, Watanabe G, Minamoto T
- Organizer
  103rdAnnual Meeting of American Association for Cancer Research
- Place of Presentation
  McCormick Place, Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
- Author(s)
  Kazuyuki Kawakami
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research (EACR 22)
- Place of Presentation
  Centre Convencions International Barcelona, Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] 多重蛍光MethyLightによるLINE-1のメチル化解析と大腸がんにおけるその臨床的意義2011
- Author(s)
  松之木愛香, 川上和之, ほか, 源利成
- Organizer
  第22回日本消化器癌発生学会
- Place of Presentation
  ホテルニューオータニ佐賀(佐賀県)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] 膵癌の新規治療標的としてのglycogen synthase kinase (GSK) 3β:化学療法戦略の新展開2011
- Author(s)
  島崎猛夫, 川上和之, ほか, 源利成
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] リンパ節および遠隔転移を伴う大腸がんにおける高頻度の LINE-1 低メチル化2011
- Author(s)
  小竹優範, 川上和之, (他4名) , 源利成
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] 多重蛍光 MethyLight による LINE-1 のメチル化解析と大腸がんにおけるその臨床的意義2011
- Author(s)
  松之木愛香, 川上和之, 小竹優範, 金子真美, 源利成
- Organizer
  第22回日本消化器癌発生学会
- Place of Presentation
  ホテルニューオータニ佐賀(佐賀県)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] リンパ節および遠隔転移を伴う大腸がんにおける高頻度のLINE-1低メチル化2011
- Author(s)
  小竹優範, 川上和之, ほか, 源利成
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23390321
[Presentation] ゲムシタビン単剤療法への挑戦：新規標的分子の同定と膵癌化学療法への展開2011
- Author(s)
  島崎猛夫、ほか、川上和之、源利成
- Organizer
  第４２回日本膵臓学会大会
- Place of Presentation
  ホテルニューキャッスル、青森
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Deregulated glycogen synthase kinase (GSK) 3β participates in invasion of glioblastoma.2011
- Author(s)
  Chikano Y, Hirose M, et al., Kawakami K, MInamoto T
- Organizer
  The 6th International Symposium of Institute Network
- Place of Presentation
  東京医科歯科大学、東京
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 再発膠芽腫に対するGSK3βを治療標的とした分子標的治療法の現状2011
- Author(s)
  中田光俊、ほか、川上和之、源利成
- Organizer
  第７０回日本脳神経外科学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 膠芽腫の新規治療標的GSK3βに関する基礎研究とトランスレーショナルリサーチ2011
- Author(s)
  中田光俊、ほか、川上和之、源利成
- Organizer
  第４９回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場、愛知
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 膵癌細胞におけるgemicitabine誘導性EMTに関連する新規分子の同定2011
- Author(s)
  島崎猛夫、ほか、川上和之、源利成
- Organizer
  第２２回日本消化器癌発生学会
- Place of Presentation
  ホテルニューオータニ佐賀、佐賀
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 切除不能進行膵癌に対するGSK3βを標的とした新規治療戦略2011
- Author(s)
  島崎猛夫、ほか、川上和之、源利成
- Organizer
  日本消化器関連学会機構JDDW(Japan Digestive Disease Week)
- Place of Presentation
  福岡国際センター、福岡サンパレス、福岡国際会議場、マリンメッセ福岡、福岡
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] Glycogen synthase kinase (GSK) 3βは神経膠芽腫の浸潤を促進する2011
- Author(s)
  近野祐里、ほか、廣瀬まゆみ、川上和之、源利成
- Organizer
  第７０回日本がん学会総会学術集会
- Place of Presentation
  名古屋国際会議場、愛知
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 膵癌の新規治療標的としてのGlycogen synthase kinase (GSK) 3β：化学療法戦略の新展開2011
- Author(s)
  島崎猛夫、ほか、川上和之、源利成
- Organizer
  第７０回日本がん学会総会学術集会
- Place of Presentation
  名古屋国際会議場、愛知
- Data Source
  KAKENHI-PROJECT-23591955
[Presentation] 膠芽腫の新規治療標的GSK3βに関する基礎研究とトランスレーショナルリサーチ2011
- Author(s)
  中田光俊, 川上和之, 源利成, ほか
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場,名古屋
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 切除不能進行膵癌に対するGSK3βを標的とした新規治療戦略2011
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  JDDW2011(日本消化器病学会週間2011)
- Place of Presentation
  福岡国際センター/福岡サンパレス/福岡国際会議場/マリンメッセ福岡,福岡
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] ゲムシタビン単剤療法の壁への挑戦:新規標的分子の同定と膵癌化学療法への展開2011
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第42回日本膵臓学会大会
- Place of Presentation
  ホテルニューキャッスル,弘前
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 膵癌に新規治療標的としてのglycogen synthase kinase (GSK)3β:化学療法戦略の新展開2011
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第70回日本癌学会総会学術集会
- Place of Presentation
  名古屋国際会議場,名古屋
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Elevation of rat plasma P-selectin in acute lung injury2011
- Author(s)
  廣瀬まゆみ, ほか, 川上和之, 源利成
- Organizer
  日本分子生物学会・第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂,金沢
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 再発膠芽腫に対するGSK3βを治療標的とした分子標的療法の現状2011
- Author(s)
  中田光俊, 川上和之, 源利成, ほか
- Organizer
  第70回日本脳神経外科学会学術総会
- Place of Presentation
  パシフィコ横浜,横浜
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] リンパ節および遠隔転移を伴う大腸がんにおける高頻度のLINE-1低メチル化2011
- Author(s)
  小竹優範, 川上和之, ほか, 源利成
- Organizer
  第70回日本癌学会総会学術集会
- Place of Presentation
  名古屋国際会議場,名古屋
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Glycogen synthase kinase(GSK)3βは神経膠芽腫の浸潤を促進する2011
- Author(s)
  近野祐里, ほか, 川上和之, 源利成
- Organizer
  第70回日本癌学会総会学術集会
- Place of Presentation
  名古屋国際会議場,名古屋
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Interleukin-1β is a signal for Trefoil factor 2 promoter methylation in gastric preneoplasia.2011
- Author(s)
  Menheniott TR, O'Connor L, Minamoto T, - 6 -Kawakami K, Tomita H, Fox JG, Wan g TC,Judd LM, Giraud AS
- Organizer
  DDW 2011
- Place of Presentation
  McCormick Place, Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Interleukin-1β is a signal for Trefoil factor 2 promoter methylation in gastric preneoplasia2011
- Author(s)
  Menheniott TR, Minamoto T, Kawakami K, et al
- Organizer
  Digestive Disease Week 2011
- Place of Presentation
  McCormick Place, Chicago, IL, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 膵癌細胞におけるgemcitabine誘導性EMTに関連する新規分子の同定2011
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第22回日本消化器癌発生学会
- Place of Presentation
  ホテルニューオータニ佐賀,佐賀
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Deregulated glycogen synthase kinase (GSK) 3β participates in invasion of glioblastoma2011
- Author(s)
  Chikano Y, et al, Kawakami K, Minamoto T
- Organizer
  The 6^<th> International Symposium of Institute Network(第6回附置研究所ネットワーク国際シンポジウム)
- Place of Presentation
  東京ドームホテル,東京
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 多重蛍光MethyLightによるLINE-1のメチル化解析と大腸がんにおけるその臨床的意義2011
- Author(s)
  松之木愛香, 川上知之, ほか, 源利成
- Organizer
  第22回日本消化器癌発生学会
- Place of Presentation
  ホテルニューオータニ佐賀,佐賀
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 膵癌細胞におけるgemcitabine誘導性EMTに関連する新規分子の同定2011
- Author(s)
  島崎猛夫，川上和之，源利成，ほか
- Organizer
  第22回日本消化器癌発生学会
- Place of Presentation
  ホテルニューオータニ佐賀，佐賀
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] 切除不能進行膵癌に対するGSK3βを標的とした新規治療戦略2011
- Author(s)
  島崎猛夫，川上和之，源利成，ほか
- Organizer
  JDDW 2011（日本消化器病学会週間 2011）
- Place of Presentation
  福岡国際センター/福岡サンパレス/福岡国際会議場/マリンメッセ福岡，福岡
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] 膠芽腫の新規治療標的GSK3βに関する基礎研究とトランスレーショナルリサーチ2011
- Author(s)
  中田光俊，川上和之，源利成，ほか
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場，名古屋
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] 膵癌に新規治療標的としてのglycogen synthase kinase (GSK) 3β：化学療法戦略の新展開2011
- Author(s)
  島崎猛夫，川上和之，源利成，ほか
- Organizer
  第70回日本癌学会総会学術集会
- Place of Presentation
  名古屋国際会議場，名古屋
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] 再発膠芽腫に対するGSK3βを治療標的とした分子標的療法の現状2011
- Author(s)
  中田光俊，川上和之，源利成，ほか
- Organizer
  第70回日本脳神経外科学会学術総会
- Place of Presentation
  パシフィコ横浜，横浜
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] Interleukin-1β is a signal for Trefoil factor 2 promoter methylation in gastric preneoplasia2011
- Author(s)
  Menheniott TR, O'Connor L, Minamoto T,Kawakami K, Tomita H, Fox JG, Wan g TC,Judd LM, Giraud AS
- Organizer
  DDW 2011
- Place of Presentation
  McCormick Place, Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] ゲムシタビン単剤療法の壁への挑戦：新規標的分子の同定と膵癌化学療法への展開2011
- Author(s)
  島崎猛夫，川上和之，源利成，ほか
- Organizer
  第42回日本膵臓学会大会
- Place of Presentation
  ホテルニューキャッスル，弘前
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] Glycogen synthase kinase (GSK) 3βは神経膠芽腫の浸潤を促進する2011
- Author(s)
  近野祐里，ほか，川上和之，源利成
- Organizer
  第70回日本癌学会総会学術集会
- Place of Presentation
  名古屋国際会議場，名古屋
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] Deregulated glycogen synthase kinase (GSK) 3b participates in invasion of glioblastoma2011
- Author(s)
  Chikano Y, et al, Kawakami K, Minamoto T.
- Organizer
  The 6th International Symposium of Institute Network (第６回附置研究所ネットワーク国際シンポジウム)
- Place of Presentation
  東京ドームホテル，東京
- Data Source
  KAKENHI-PROJECT-23659643
[Presentation] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2010
- Author(s)
  Miyashita K, et al, Kawakami K, Minamoto T
- Organizer
  101^<st> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Washington Convention Center (U.S.A.)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IA non-smallcell lung cancer2010
- Author(s)
  SaitoK, et al, Kawakami K, Minamoto T
- Organizer
  101^<st> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Washington Convention Center (U.S.A.)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] 消化管がん組織検体資源化による進行再発大腸がんに対する抗EGFR分子標的医療の均てん化への取り組み2010
- Author(s)
  藤田秀人, 川上和之, ほか, 源利成
- Organizer
  第110回同本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] TFF2 inhibits tumour growth and is a target for epigenetic silencing in gastric cancer2010
- Author(s)
  Menheniott T, Minamoto T, Kawakami K, et al.
- Organizer
  DDW (Digestive Disease Week) 2010
- Place of Presentation
  Morial Convention Center (U.S.A.)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IAnon-small cell lung cancer.2010
- Author(s)
  斎藤健一郎, 川上和之, (他3名), 源利成.
- Organizer
  101^<st> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Washington Convention Center (USA)
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用:Project Kの試み2010
- Author(s)
  小竹優範, 川上和之, ほか, 源利成
- Organizer
  第65回日本消化器外科学会総会
- Place of Presentation
  海峡メッセ下関(山口県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用:Project Kの試み.2010
- Author(s)
  小竹優範, (他8名), 川上和之, 源利成.
- Organizer
  第65回日本消化器外科学会総会
- Place of Presentation
  海峡メッセ下関(山口県).
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] 熱ショック誘導性新規がん抑制遺伝子の解析2010
- Author(s)
  中島日出夫, 川上和之, 源利成, ほか
- Organizer
  第21回日本消化器癌発生学会
- Place of Presentation
  軽井沢プリンスホテル、(長野県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 methylation is stable in primary and synchronous metastatic colorectal cancertissues.大腸癌原発巣および転移巣におけるLINE-1メチル化の検討2010
- Author(s)
  松之木愛香,川上和之, ほか, 源利成
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用2010
- Author(s)
  小竹優範, 川上和之, ほか, 源利成
- Organizer
  第21回日本消化器癌発生学会
- Place of Presentation
  軽井沢プリンスホテル、(長野県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Distinct DNA methylation profiles and genetic signatures in human colorectal cancer.大腸癌におけるDNAメチル化パターンと遺伝子変異の関連2010
- Author(s)
  小竹優範, 川上和之, ほか, 源利成
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Distinct DNA methylation profiles and genetic signatures in human colorectal cancer.2010
- Author(s)
  小竹優範, 川上和之, (他4名), 源利成.
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府).
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 methylation is stable in primary and synchronous metastatic colorectal cancer tissues.2010
- Author(s)
  松之木愛香, 川上和之, (他3名), 源利成.
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer.2010
- Author(s)
  Saito K, Kawakami K, Matsumoto I, Oda M, Watanabe G, Minamoto T
- Organizer
  101st Annual Meeting of American Association for Cancer Research 2010
- Place of Presentation
  Walter E. Washington Convention Center, Washington DC, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma.2010
- Author(s)
  Miyashita K, Kawakami K, Nakada M, Shakoori A, Fujisawa H, Hayashi Y, HamadaJ, Minamoto T
- Organizer
  101st Annual Meeting of American Association for Cancer Research 2010
- Place of Presentation
  Walter E. Washington Convention Center, Washington DC, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer2010
- Author(s)
  Saito K, et al, Kawakami K, Minamoto T
- Organizer
  101^<st> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Walter E. Washington Convention Center (U.S.A)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 膵癌細胞の抗がん剤誘導性上皮-間葉移行とGSK3β阻害による制御機構2010
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第21回日本消化器癌発生学会
- Place of Presentation
  軽井沢プリンスホテルウエスト(長野県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Effect of GSK3βinhibition agaisnt gemcitabine-induced epithelial-mesenchymal transition and invasive ability of pancreatic cancer cells: its therapuetic implication.2010
- Author(s)
  Shimasaki T, Ishigaki Y, Takata T, NakamuraY, Kitano A, Kawakami K, Tomosugi N, Minamoto T, Motoo Y.
- Organizer
  Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society 2010
- Place of Presentation
  福岡国際会議場,福岡
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Clinical trial for treatment of recurrent glioblastoma targeting deregulated GSK3β in combination with temozolomide.Glycogen synthase kinase (GSK)3βを分子標的とした再発神経膠芽腫に対する化学療法2010
- Author(s)
  中田光俊, 川上和之, 源利成, ほか
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 再発膠芽腫に対するGSK3β阻害薬剤を使用した第I/II相臨床試験(Phase I/II clinical trial targeting GSK3β for the recurrent glioblastoma)2010
- Author(s)
  中田光俊, 川上和之, 源利成, ほか
- Organizer
  第28回日本脳腫瘍学会学術集会
- Place of Presentation
  軽井沢プリンスホテルウエスト(長野県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Giraud. TFF2 inhibits tumour growth and is a target for epigenetic silencing in gastric cancer.2010
- Author(s)
  Menheniott T, Peterson AJ, O'Connor L, Wan g TC, Fox JG, Minamoto T, Kawakami K, Judd LM, Andrew S
- Organizer
  DDW 2010
- Place of Presentation
  Ernest N. Morial Convention Center, New Orleans, Louisiana, U.S.A.
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Role and regulation of glycogen synthase kinase 3β in gemcotabine-induced EMT of pancreatic cancer cells.Gemcitabineによる膵癌細胞のEMTにおけるglycogen synthase kinase(GSK)3βの役割とその制御2010
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第69回日本癌学会学術集会,English Workshop
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Glycogen synthase kinase 3β inhibition affects methylation status of the 06-methylguanine DNA methyltransferase (MGMT) promoter and MGMT gene expression in human glioma cells2010
- Author(s)
  llya V.Pyko, 川上和之, 源利成, ほか
- Organizer
  第11回日本分子脳神経外科学会
- Place of Presentation
  東北大学医学部艮陵会館,(宮城県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2010
- Author(s)
  Miyashita K, et al, Kawakami K, Minamoto T
- Organizer
  101^<st> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Walter E. Washington Convention Center (U.S.A)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Distinct DNA methylation profiles and genetic signatures in human colorectal cancer.大腸癌におけるDNAメチル化パターンと選伝子変異の関連2010
- Author(s)
  小竹優範, 川上和之, ほか, 源利成
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用2010
- Author(s)
  小竹優範, 川上和之, ほか, 太田哲生, 源利成
- Organizer
  第21回日本消化器癌発生学会
- Place of Presentation
  軽井沢プリンスホテルウエスト(長野県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] TFF2 inhibits tumour growth and is a target for epigenetic silencing in gastric cancer2010
- Author(s)
  Menheniott T, Minamoto T, Kawakami K, et al.
- Organizer
  DDW(Digestive Disease Week)2010
- Place of Presentation
  Ernest N. Morial Convention Center (U.S.A.)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Pathological role for deregulated glycogen synthase kinase(GSK)3β inpancreatic cancer proliferation and invasion.膵がん細胞の増殖と浸潤におよぼすglycogen sypthase kinase(GSK)3βの病的作用2010
- Author(s)
  北野綾子, ほか, 川上和之, 源利成
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用:Project Kの試み2010
- Author(s)
  小竹優範, 川上和之, ほか, 太田哲生, 源利成
- Organizer
  第65回日本消化器外科学会総会
- Place of Presentation
  海峡メッセ下関(山口県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Effect of GSK3β inhibition agaisnt gemcitabine-induced epithelial-mesenchymal transition and invasive ability of pancreatic cancer cells : its theranuetic implication2010
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et al.
- Organizer
  Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society 2010(第41回日本膵臓学会大会/第14回国際膵臓学会合同学会)
- Place of Presentation
  福岡国際会議場(福岡県))
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Pathological role for deregulated glycogen synthase kinase(GSK)3β in glioblastoma proliferation and invasion.神経膠芽腫の増殖と浸潤におよぼすglycogen synthase kinase(GSK)3βの病的作用2010
- Author(s)
  近野祐里, ほか, 川上和之, 源利成
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 熱ショック誘導性新規がん抑制遺伝子の解析2010
- Author(s)
  中島日出夫, 川上和之, 源利成, ほか
- Organizer
  第21回日本消化器癌発生学会
- Place of Presentation
  軽井沢プリンスホテルウエスト(長野県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Pathological role for deregulated GSK3β in pancreatic cancer proliferation and invasion2010
- Author(s)
  Kitano A, et al, Kawakami K, Minamoto T
- Organizer
  The Joint Symposium of the 5^<th> International Symposium of Institute Network and the International Symposium of Commemorating Inauguration of Kanazawa University Cancer Research Institute
- Place of Presentation
  KKRホテル金沢(石川県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Targeting glycogen synthase kinase 3β in adult recurrent glioblastomas2010
- Author(s)
  Nakada M, Kawakami K, Minamoto T, et al.
- Organizer
  7^<th> Meeting of Asian Society for Neuro-Oncology
- Place of Presentation
  JW Marriott Hotel (Korea)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] 膠芽腫におけるGSK3β研究の進展とその阻害薬剤を使用した再発膠芽腫に対する第I/II相臨床試験2010
- Author(s)
  中田光俊, 川上和之, 源利成, ほか
- Organizer
  第69回日本脳神経外科学会学術総会
- Place of Presentation
  福岡コンベンションセンター,福岡国際会議場,マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] Pathological role for deregulated GSK3β in pancreatic cancer proliferation and invasion.2010
- Author(s)
  Kitano A, Shimasaki T, Chikano Y, Nakada M, Higashi T, Ishigaki Y, Sai Y, Miyamoto K, Motoo Y, Kawakami K, Minamoto T
- Organizer
  The Joint Symposium of the 5thInternational Symposium of Institute Network and the International Symposium of Commemorating Inauguration of Kanazawa University Cancer Research Institute
- Place of Presentation
  KKRホテル金沢,石川
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] LINE-1 methylation is stable in primary and synchronous metastatic colorectal cancer tissues.大腸癌原発巣および転移巣におけるLrNE-1メチル化の検討2010
- Author(s)
  松之木愛香, 川上和之, ほか, 源利成
- Organizer
  第69回日本癌学会学術集会
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Data Source
  KAKENHI-PROJECT-22249051
[Presentation] TheCpG islamd methylator phenotype as a predictor of response to 5FU-based chemotherapy in colon cancer.2009
- Author(s)
  Iacopetta B, Kawakami K
- Organizer
  第68回日本癌学会総会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Allele-specific inhibition of thymidylate synthase expression by small interfering RNA.2009
- Author(s)
  川上和之, (他4名), 源利成.
- Organizer
  Annual Meeting 2009 0f the American Association for Cancer Research
- Place of Presentation
  Colorado Convention Center(USA)
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Augmentation of LINE-1 expression is apossible mechanism underling cytotoxic effect of 5-FU in colorectal cancer.2009
- Author(s)
  川上和之, (他4名), 源利成.
- Organizer
  第68回日本癌学会総会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] DNAメチル化マーカーによる大腸がんの予後・抗癌剤感受性診断.2009
- Author(s)
  川上和之, 源利成.
- Organizer
  第17回日本消化器関連学会週間(JDDw 2009)/第51回日本消化器病学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1メチル化解析による大腸がんの予後・抗癌剤感受性診断.2009
- Author(s)
  川上和之, 源利成.
- Organizer
  第20回消化器癌発生学会総会
- Place of Presentation
  オリエンタルホテル広島(広島県)
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Allele-specific inhibition of thymidylate synthase expression by small interfering RNA2009
- Author(s)
  川上和之, 源利成, et al
- Organizer
  Annual Meeting 2009 of the American Association for Cancer Research
- Place of Presentation
  Colorado Convention Center, Denver, CO, (U.S.A)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] DNAメチル化マーカーによる大腸がんの予後・抗癌剤感受性診断2009
- Author(s)
  川上和之, 源利成, ほか
- Organizer
  第17回日本消化器関連学会週間 (JDDW 2009)
- Place of Presentation
  国立京都国際会館 (京都府)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1メチル化解析による大腸がんの予後・抗癌剤感受性診断2009
- Author(s)
  川上和之, 源利成, ほか
- Organizer
  第20回消化器癌発生学会総会
- Place of Presentation
  オリエンタルホテル広島 (広島県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Glycogen synthase kinase (GSK) 3β sustains colon cancer cells survival by modulating JNK- mediated pathway2009
- Author(s)
  Jin MJ, Kawakami K, Minamoto T, et al
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Pathological roles for glycogen synthase kinase (GSK) 3β in proliferation and motility of pancreatic cancer cells2009
- Author(s)
  北野綾子, 川上和之, 源利成, et al
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Glycogen synthase kinase (GSK)-3β inhibition for cancer treatment2009
- Author(s)
  Minamoto T, Kawakami K, et al
- Organizer
  第14回日韓がん研究ワークシヨップ
- Place of Presentation
  ANAクラウンプラザホテル金沢 (石川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] GSK3βによる膵がん細胞の増殖と浸潤の制御2009
- Author(s)
  北野綾子, 川上和之, 源利成, ほか
- Organizer
  第20回消化器癌発生学会総会
- Place of Presentation
  オリエンタルホテル広島 (広島県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] ヒト消化管がん組織検体資源化の試み : がん研究とがんの個別化医療への応用2009
- Author(s)
  山下要, 川上和之, 源利成, ほか
- Organizer
  第47回日本がん治療学会総会学術集会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] The CpG islamd methylator phenotype as a predictor of response to 5FU-based chemotherapy in colon cancer2009
- Author(s)
  Iacopetta B, Kawakami K, et al
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Augmentation of LINE-1 expression is a possible mechanism underling cytotoxic effect of 5-FU in colorectal cancer2009
- Author(s)
  川上和之, 源利成, et al
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Chemotherapy-induced changes in morphology and invasion ability of pancreatic cancer cells2009
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et al
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1メチル化解析による大腸がんの予後・抗癌剤感受性診断.2009
- Author(s)
  川上和之, 源利成
- Organizer
  第20回消化器癌発生学会総会:シンポジウム(3)消化器癌診断の新展開
- Place of Presentation
  オリエンタルホテル広島(広島県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Glycogen synthase kinase(GSK)-3β inhibition for cancer treatment.2009
- Author(s)
  Minamoto T, Kawakami K
- Organizer
  第14回日韓がん研究ワークショップ
- Place of Presentation
  ANAクラウンプラザホテル金沢(石川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] ヒト消化管がん組織検体資源化の試み:がん研究とがんの個別化医療への応用.2009
- Author(s)
  山下要, 川上和之, ほか, 源利成
- Organizer
  第47回日本がん治療学会総会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] GSK3β阻害による抗がん剤誘導性上皮-間葉移行の制御に基づく新規膵癌治療ストラテジー.2009
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第20回消化器癌発生学会総会:シンポジウム(2)消化器癌治療の新展開
- Place of Presentation
  オリエンタルホテル広島(広島県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] GSK3βによる膵がん細胞の増殖と浸潤の制御.2009
- Author(s)
  北野綾子, 島崎猛夫, ほか, 川上和之, 源利成
- Organizer
  第20回消化器癌発生学会総会:ミニシンポジウム(5)-3消化器癌の分子基盤:浸潤・転移-3
- Place of Presentation
  オリエンタルホテル広島(広島県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] DNAメチル化マーカーによる大腸がんの予後・抗癌剤感受性診断.2009
- Author(s)
  川上和之, 源利成
- Organizer
  第17回日本消化器関連学会週間(JDDW 2009)/第51回日本消化器病学会大会:シンポジウム6.
- Place of Presentation
  国立京都国際会館,グランドプリンスホテル京都(京都府)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Allele-specific inhibition of thymidylate synthase expression by small interfering RNA.2009
- Author(s)
  Kawakami K, et al., Minamoto T.
- Organizer
  100^<th> Annual Meeting of the American Association for Cancer Research 2009
- Place of Presentation
  Denver, CO(U.S.A)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] The CpG islamd methylator phenotype as a predictor of response to 5FU-based chemotherapy in colon cancer.2009
- Author(s)
  Iacopetta B, Kawakami K.
- Organizer
  第68回日本癌学会総会学術集会International Session
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] GSK3β阻害剤と塩酸ゲムシタビンの併用による膵癌の新規治療戦略と分子基盤.2009
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第40回日本膵臓病学会大会,シンポジウム2
- Place of Presentation
  京王プラザホテル(東京都)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Pathological roles for glycogen synthase kinase(GSK)3β in proliferation and motility of pancreatic cancer cells2009
- Author(s)
  Kitano A, Shimasaki T, et al., Kawakami K, Minamoto T
- Organizer
  第68回日本癌学会総会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Glycogen synthase kinase(GSK)3β sustains colon cancer cells survival by modulating JNK-mediated pathway.2009
- Author(s)
  Jin M, Kawakami K, Shimasaki T, et al., Minamoto T
- Organizer
  第68回日本癌学会繊学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Augmentation of LINE-1 expression is a possible mechanism underling cytotoxic effect of 5-FU in colorectal cancer2009
- Author(s)
  Kawakami K, et al., Minamoto T
- Organizer
  第68回日本癌学会総会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Chemotherapy-induced changes in morphology and invasion ability of pancreatic cancer cells2009
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et al.
- Organizer
  第68回日本癌学会総会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発.2008
- Author(s)
  川上和之, (他4名), 源利成.
- Organizer
  第19回日本消化器癌発生学会総会
- Place of Presentation
  別府亀の井ホテル(大分県)
- Year and Date
  2008-08-28
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008
- Author(s)
  Kawakami K, Minamoto T, et al
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA, U. S. A.
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発.2008
- Author(s)
  川上和之, 源利成ほか
- Organizer
  第19回日本消化器癌発生学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer.2008
- Author(s)
  川上和之, (他5名), 源利成.
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego Convention Center (USA)
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] 慢性進行性疾患の創薬標的GSK3βの消化器がんにおける発現, 活性と機能解析2008
- Author(s)
  川上和之, 源利成ほか
- Organizer
  第16回日本消化器関連学会週間(JDDW 2008)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 hypomethylation is a novel prognostic factor in non-small cell lung cancer.2008
- Author(s)
  斎藤健一郎, 川上和之, (他3名), 源利成.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Inhibition of GSK3β activity attenuates proliferation of human colon cancer cells in rodents.2008
- Author(s)
  Minamoto T, Kawakami K, et al
- Organizer
  Annual Meeting 2008 of the AmericanAssociation for Cancer Research
- Place of Presentation
  San Diego, CA, U.S.A.
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/β-catenin signaling in human colorectal cancer2008
- Author(s)
  Minamoto T Kawakami K, et al
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] LINE-1 hypo- methylation is a novel prognostic factor in non-small cell lung cancer2008
- Author(s)
  Saito K. Kawakami K, et al
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20390353
[Presentation] 膵癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008
- Author(s)
  島崎猛夫, 石垣靖人, 夏啓勝, 中谷直喜, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
- Organizer
  第19回日本消化器癌発生学会総会ミニシンポジウム
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Distinct pathologic property of glycogen synthase kinase 3β (GSK3β) in gastrointestinal, pancreatic and liver cancers.胃がん, 大腸がん, 膵がんと肝がんに共通するglycogen synthase kinase 3β(GSK3β)の病的作用2008
- Author(s)
  Mai W, Miyashita K, Shakoori A, Shimasaki T, Yasumoto K, Yoshiharu Motoo, Kawakami K, Minamoto T.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Inhibition of GSK3β activity attenuates proliferation of human colon cancer cells in rodents2008
- Author(s)
  Minamoto T, Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K.
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA, U.S.A.
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay2008
- Author(s)
  Mai W, Shakoori A, Miyashita K, Zhang B, Motoo Y, Kawakami K, Takahashi Y, Minamoto T.
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA, U.S.A
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008
- Author(s)
  Kawakami K, Jin MJ, Saito K, Miyashita K, Mai W, Watanabe Go, Minamoto T.
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA, U.S.A
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] LINE-1 hypomethylation is a novel prognostic factor in non-small cell lung cancer. 非小細胞肺癌におけるLINE-1 低メチル化は新規の予後因子である2008
- Author(s)
  Saito K, Kawakami K, Matsumoto I, Oda M, Watanabe G, Minamoto T.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008
- Author(s)
  川上和之, 金明姫, 斉藤健一郎, 麦威, 宮下勝吉, 源利成
- Organizer
  第19回日本消化器癌発生学会総会ミニシンポジウム(8)
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] GSK3β inhibition sensitizes glioblastoma cells to chemotherapy and radiation by modulating p53 and Rb pathways. GSK3β阻害によるp53 とRb 経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾2008
- Author(s)
  Miyashita K, Nakada M, Fujisawa H, Mai W, Kawakami K, Jun-ichiro Hamada, Minamoto T.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer : basic analysis for future clinical trial2008
- Author(s)
  Shimasaki T, Ishigaki, Y Nakaya N, Nakajima H, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 神経膠芽腫におけるGSK3βの発現・活性と機能解析2008
- Author(s)
  宮下勝吉, 中田光俊, 吉田優也, 藤沢弘範, 林裕, 川上和之, 源利成, 濱田潤一郎
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 膵癌における新しい分子標的としてのGSK3βとその関連遺伝子群の解析2008
- Author(s)
  島崎猛夫, 石垣靖人, 中谷直喜, 中島日出夫, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
- Organizer
  第6回日本臨床腫瘍学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/β-catenin signaling in human colorectal cancer2008
- Author(s)
  Minamoto T, Yamashita K, Kawakami K.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 慢性進行性疾患の創薬標的GSK3βの消化器がんにおける発現, 活性と機能解析. 第16回日本消化器関連学会週間(JDDW 2008)2008
- Author(s)
  川上和之, 島崎猛夫, 源利成
- Organizer
  第50回日本消化器病学会大会 : ワークショップ13
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 神経膠芽腫におけるGSK3βの発現・活性と機能解析.2008
- Author(s)
  宮下勝吉, 川上和之, 源利成, ほか
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 慢性進行性疾患の創薬標的GSK3Pの消化器がんにおける発現, 活性と機能解析.2008
- Author(s)
  川上和之, ほか, 源利成
- Organizer
  第16回日本消化器関連学会週間(JDDW 2008)/第50回日本消化器病学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/p-catenin signaling in human colorectal cancer.2008
- Author(s)
  Minamoto T, et al Kawakami K
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008
- Author(s)
  川上和之, ほか, 源利成
- Organizer
  第19回日本消化器癌発生学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 騨癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第19回日本消化器癌発生学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for thepatients with primary colorectal cancer.2008
- Author(s)
  Kawakami K, et al Minamoto T
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Detection of active fraction of GSK3βin cancer cells by non-radioisotopic in vitro kinase assay.2008
- Author(s)
  Mai W, Kawakami K, et al, Minamoto T
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Inhibition of GSK3βactivity attenuates proliferation of human colon cancer cells in rodents.2008
- Author(s)
  Minamoto T, et al Kawakami K.
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San-Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] GSK3β阻害によるp53とRb経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾.2008
- Author(s)
  Miyashita K, Kawakami K., et al, Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Combined effect of gemcitabine and GSK3βinhibitor against pancreatic cancer : basic analysis for future clinical trial.2008
- Author(s)
  Shimasaki T, Kawakami K., et al, Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 非小細胞肺癌におけるLINE-1低メチル化は新規の予後因子である2008
- Author(s)
  Saito K, Kawakami K., et al, Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 胃がん, 大腸がん, 譚がんと肝がんに共通するglycogen synthase kinase 3β(GSK3P)の病的作用.2008
- Author(s)
  Mai W, et al, Kawakami K. Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Detection of active fraction of GSK3 in cancer cells by non- radioisotopic in vitro kinase assay2008
- Author(s)
  Mai W, Kawakami K, et.al., Minamoto T
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  San Diego, U.S.A
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] 神経膠芽腫におけるGSK3βの発現・活性と機能解析2008
- Author(s)
  宮下勝吉, 川上和之, ほか
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Inhibition of GSK3I3 activity attenuates proliferation of human colon cancer cells in rodents2008
- Author(s)
  Minamoto T, et.al. ; Kawakami K
- Organizer
  Annual Meeting 2008 of the American Association for Cancer Research
- Place of Presentation
  SanDiego,U.S.A
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008
- Author(s)
  Kawakami K, et.al., Minamoto T
- Organizer
  Annual Meeting 2008 of the Amedcan Association for Cancer Research
- Place of Presentation
  San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] 胃がん, 大腸がん, 膵がんと肝がんに共通するglycogen synthase kinase 3β(GSK3β)の病的作用2008
- Author(s)
  Mai W, et.al., Kawakami K, Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] 慢性進行性疾患の創薬標的GSK3βの消化器がんにおける発現, 活性と機能解析2008
- Author(s)
  川上和之, ほか, 源利成
- Organizer
  第16回日本消化器関連学会週間(JDDW2008)/第50回日本消化器病学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] 非小細胞肺癌におけるLINE-1低メチル化は新規の予後因子である2008
- Author(s)
  Saito K, Kawakami K, et.al., Minamoto T
- Organizer
  第67向日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/β-catenin signaling in human colorectal cancer2008
- Author(s)
  Minamoto T, et.al., Kawakami K
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer : basic analysis for future clinical trial2008
- Author(s)
  Shimasaki T, Kawakami K, et.al., Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] GSK3β阻害によるp53とRb経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾2008
- Author(s)
  Miyashita K, Kawakami K. et.al., Minamoto T
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] 膵癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか
- Organizer
  第19回日本消化器癌発生学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-20015018
[Presentation] mRNA expression of gamma glutamyl hydrolase (GGH) is negatively associated with DNA methylation status in primary colorectal cancer2007
- Author(s)
  Kawakami K, et. al.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  アメリカ合衆国ロサンジェルス
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Deregulated GSK3β activity in colorectal cancer : its association with tumor cell survival and proliferation2007
- Author(s)
  Minamoto T, Shakoori A, Ougolkov A, Yu ZW, Zhang B, Billadeau DD, Takahashi Y, Kawakami K.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  Los Angels, CA
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Synergistic effect of gemcitabine and GSK3β inhibitor against human pancreas cancer : GSK3β as a new therapeutic molecular target2007
- Author(s)
  Shimasaki T, Ishigaki Y, Zhao X, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
- Organizer
  Annual Meeting of American Pancreatic Association
- Place of Presentation
  Chicago, Illinois, U.S.A.
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer resulting in altered gene expression profiles2007
- Author(s)
  Shimasaki T, Ishigaki Y, Nakaya N, Zhao X, Tomosugi N, Tanaka T, Kawakami K, Minamoto T, Motoo Y
- Organizer
  The Second Meeting of Asian-Oceanic Pancreatic Association(AOPA)
- Place of Presentation
  Kobe, Japan
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Minamoto T, et. al. Kawakami K.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] mRNA expression of gamma glutamyl hydrolase(GGH)is negatively associated with DNA methylation status in primary colorectal cancer2007
- Author(s)
  Kawakami K, Ruszkiewicz A, Fukushima M, Minamoto T, Iacopetta B.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  Los Angels, CA
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Deregulated GSK3β activity in colorectal cancer: its association with tumor cell survival and proliferation2007
- Author(s)
  Minamoto T, et. al. Kawakami K.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  アメリカ合衆国ロサンジェルス
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] 消化器がんの新しい治療標的GSK3βの発現,活性,機能解析2007
- Author(s)
  川上和之, ほか
- Organizer
  第18回日本消化器がん発生学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer2007
- Author(s)
  Kawakami K, et. al.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Wntシグナル制御破綻に関わる新しい分子細胞機構の解明と大腸がん制御への展開2007
- Author(s)
  源利成, ほか川上和之
- Organizer
  第62回日本消化器外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) in glioblastoma attenuates tumor cells' viability and induces apoptosis depending on p53(GSK3β阻害による神経膠芽腫細胞の生存・増殖抑制とp53関連アポトーシス誘導機構の解明)2007
- Author(s)
  Miyashita K, Mai W, FujisawaH, Hamada J-I, Kawakami K, Minamoto T.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Wntシグナル制御破綻に関わる新しい分子細胞機構の解明と大腸がん制御への展開2007
- Author(s)
  源利成, 山下要, 高橋豊, 川上和之
- Organizer
  第62回日本消化器外科学会定期学術集会シンポジウム1
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 塩酸ゲムシタビンとGSK3β阻害薬の膵癌細胞への抗腫瘍効果とその分子機構2007
- Author(s)
  島崎猛夫, 中島日出夫, 石垣靖人, 本西哲, 友杉直久, 田中卓二, 川上和之, 源利成, 元雄良治
- Organizer
  第38回日本膵臓学会大会シンポジウム : 膵癌の基礎と臨床
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer(大腸癌における予後因子としてのLINE-1メチル化)2007
- Author(s)
  Kawakami K, Mai W, Miyashita K, Watanabe G, Minamoto T.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 消化器がんの新しい治療標的GSK3βの発現, 活性, 機能解析2007
- Author(s)
  川上和之, 麦威, 島崎猛夫, 宮下勝吉, 安本和生, 高橋豊, 大井章史, 元雄良治, 源利成
- Organizer
  第18回日本消化器がん発生学会総会W2
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Expression, deregulated activity and pathologic role of GSK3β in gastrointestinal, pancreas and liver cancers2007
- Author(s)
  Mai W, Miyashita K, Shakoori A, Shimasaki T, Motoo Y, Kawakami K, Minamoto T.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Inhibition of glycogen synthase kinase 3β(GSK3β)attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Minamoto T, Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 膵癌に対する塩酸ゲムシタビンとGSK3β阻害剤併用の抗腫瘍効果とその分子機構2007
- Author(s)
  島崎猛夫, 石垣靖人, 趙霞, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
- Organizer
  第18回日本消化器がん発生学会総会W3
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer : GSK3β as a new therapeutic target2007
- Author(s)
  Shimasaki T, Ishigaki Y, Nakajima H, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
- Organizer
  第66 回日本癌学会学術総会English Workshops 14 Kinase Inhibitors
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] mRNA expression of gamma glutamyl hydrolase (GGH) is negatively associated with DNA methylation status in primary colorectal cancer2007
- Author(s)
  Kawakami, K., et. al.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  Los Angeles, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Deregulated GSK3β activity in colorectal cancer: its association with tumor cell survival and proliferation.2007
- Author(s)
  Minamoto T, et. al., Kawakami K
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  アメリカ合衆国ロサンジェルス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Inhibition of glycogen synthase kinase 3B (GSK3B) attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Minamoto, T., et. al., Kawakami, K
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Deregulated GSK3B activity in colorectal cancer : its association with tumor cell survival and proliferation2007
- Author(s)
  Minamoto, T., et. al., Kawakami, K
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  Los Angeles, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] 消化器がんの新しい治療標的GSK3βの発現,活性,機能解析.2007
- Author(s)
  川上和之, ほか
- Organizer
  第18回日本消化器がん発生学会総会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer2007
- Author(s)
  Kawakami, K., et. al.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] mRNA expression of gamma glutamyl hydrolase(GGH)is negatively associated with DNA methylation status in primary colorectal cancer.2007
- Author(s)
  Kawakami K, et. al.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  アメリカ合衆国ロサンジェルス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Wntシグナル制御破綻に関わる新しい分子細胞機構の解明と大腸がん制御への展開.2007
- Author(s)
  源利成, ほか川上和之.
- Organizer
  第62回日本消化器外科学会定期学術集会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer.2007
- Author(s)
  Kawakami K, et. al.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Inhibition of glycogen synthase kinase 3β(GSK3β)attenuates proliferation of human colon cancer cells in rodents.2007
- Author(s)
  Minamoto T, et. al., Kawakami K
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Deregulated GSK3β activity in colorectal cancer: its association with tumorcell survival and Proliferation2007
- Author(s)
  Minamoto T, et. al., Takahashi Y, Kawakami K.
- Organizer
  Annual Meeting 2007 of the American Association for Cancer Research
- Place of Presentation
  アメリカ合衆国ロサンジェルス
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) attenuates proliferation of human colon cancer cells in rodents2007
- Author(s)
  Minamoto T, et. al., Takahashi Y, Kawakami K.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients withcolorectal cancer2007
- Author(s)
  Kawakami K, et. al., Minamoto T.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer: GSK3β as a new therapeutic target2007
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et. al.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Expression, deregulated activity and pathologic role of GSK3β in gastrointestinal, pancreas and liver cancers2007
- Author(s)
  Mai W, et. al., Kawakami K, Minamoto T.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] mRNA expression of gamma glutamyl hydrolase(GGH) is negatively associated with DNA methylation status in primary colorectal cancer2007
- Author(s)
  Kawakami K, Minamoto T, et. al.
- Organizer
  Annual Meetlng 2007 of the American Association for Cancer Research
- Place of Presentation
  アメリカ合衆国ロサンジェルス
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Wntシグナル制御破綻に関わる新しい分子細胞機構の解明と大腸がん制御への展開2007
- Author(s)
  源利成, ほか, 高橋豊, 川上和之.
- Organizer
  第62回日本消化器外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancerresulting in altered gene expression Profiles2007
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et. al.
- Organizer
  The Second Meeting of Asian-Oceanic Pancreatic Association (AOPA)
- Place of Presentation
  神戸
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Synergistic effect of gemcitabine and GSK3β inhibitor against human pancreascancer: GSK3β as a new therapeutic molecular target2007
- Author(s)
  Shimasaki T, Kawakami K, Minamoto T, et. al.
- Organizer
  Annual Meeting of American Pancreatic Association
- Place of Presentation
  アメリカ合衆国シカゴ
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 消化器がんの新しい治療標的GSK3βの発現,活性,機能解析2007
- Author(s)
  川上和之, ほか, 高橋豊, 源利成.
- Organizer
  第18回日本消化器がん発生学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 膵癌に対する塩酸ゲムシタビンとGSK3β阻害剤併用の抗腫瘍効果とその分子機構2007
- Author(s)
  島崎猛夫, 川上和之, 源利成, ほか.
- Organizer
  第18回目本消化器がん発生学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 消化器癌細胞におけるGSK3β活性の非放射性測定法による検出と機能解析2006
- Author(s)
  麦威, 宮下勝吉, 島崎猛夫, 中島日出夫, 元雄良治, 川上和之, 源利成
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] チミジル酸合成酵素の遺伝子多型とLOH解析に基づく大腸癌の予後判定と化学療法の効果予測2006
- Author(s)
  川上和之, 渡邊剛, 源利成
- Organizer
  第17回日本消化器癌発生学会総会ワークショップ(2)
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 新しいがん標的GSK3βの活性阻害による移植大腸癌細胞の増殖抑制2006
- Author(s)
  源利成, シャクーリアッバス, 麦威, 宮下勝吉, 安本和生, 高橋豊, 川上和之
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 新規がん標的酵素GSK3βの発現,活性・機能解析と消化器がん制御への応用2006
- Author(s)
  源利成, 高橋豊, 元雄良治, 川上和之
- Organizer
  第44回日本癌治療学会総会ワークショップ3
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] Wnt シグナルに関わる大腸癌の新しい分子細胞メカニズムとがん制御への展開2006
- Author(s)
  源利成, 高橋豊, 川上和之
- Organizer
  DDW-Japan 2006 : ワークショップ9(消化器病学会・消化器内視鏡学会合同)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 神経膠芽腫におけるGSK3βの発現,活性と機能解析2006
- Author(s)
  宮下勝吉, 麦威, 藤沢弘範, 濱田潤一郎, 川上和之, 源利成
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 大腸癌の新規標的酵素GSK3βの活性機能解析とがん制御への応用2006
- Author(s)
  源利成, 高橋豊, 川上和之
- Organizer
  DDW-Japan 2006 : シンポジウム2(消化器病学会)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 遺伝子多型を利用した抗癌剤のtailored molecularmodulation 法開発2006
- Author(s)
  川上和之, 渡邊剛, 源利成
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390363
[Presentation] 遺伝子多型を利用した抗癌剤のtailored molecular modulation法開発2006
- Author(s)
  川上和之, ほか
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] チミジル酸合成酵素の遺伝子多型とLOH解析に基づく大腸癌の予後判定と化学療法の効果予測.2006
- Author(s)
  川上和之, ほか
- Organizer
  第17回日本消化器がん発生学会総会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591458
[Presentation] Development of tailored molecular modulation for 5-FU by targeting Thymidylate synthase gene polymorphism2006
- Author(s)
  Kawakami, K., et. al.
- Organizer
  65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591458

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88. WANG Timothy C.

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KAWAKAMI Kazuyuki 川上 和之

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レトロポゾンの制御によるがん治療開発Principal InvestigatorOngoing

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Molecular analysis of colorectal cancer with LINE-1 hypomethylation and its application to cancer diagnosis and therapyPrincipal Investigator

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Mechanistic analysis on DNA methylation in colorectal cancer and its application to diagnosis and therapyPrincipal Investigator

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Genetic and epigenetic analyses of folate and nudeotide metabolizing enzymes in gastrointestinal cancerPrincipal Investigator

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Molecular characterization of lung cancer by DNA methylation profilePrincipal Investigator

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末梢血中遊離DNAのエピジエネティクスを標的とした癌分子診断Principal Investigator

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KAWAKAMI Kazuyuki 川上和之