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minamoto toshinari  源 利成

ORCIDConnect your ORCID iD *help
… Alternative Names

MINAMOTO Toshinari  源 利成

源 俊成  ミナモト トシナリ

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Researcher Number 50239323
Other IDs
External Links
Affiliation (Current) 2021: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help 2011 – 2020: 金沢大学, がん進展制御研究所, 教授
2013: 金沢大学, がん研究所, 教授
2001 – 2010: 金沢大学, がん研究所, 教授
1999 – 2001: 金沢大学, がん研究所, 助教授
Review Section/Research Field
Principal Investigator
Digestive surgery / Digestive surgery / Biological Sciences / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Digestive surgery / Gastroenterology / Biological Sciences / General internal medicine (including Psychosomatic medicine) / Cerebral neurosurgery … More / Digestive surgery / Human pathology / Pathological medical chemistry / Neurosurgery / Basic Section 55020:Digestive surgery-related / Basic Section 53010:Gastroenterology-related Less
Keywords
Principal Investigator
大腸がん / GSK3β / 大腸癌 / β-カテニン / 分子標的 / シグナル伝達 / β-catenin / β-TrCP / がん分子標的 / Wnt … More / CRD-BP / RNAトランス因子 / 消化器がん / 治療 / APC / K-ras / βTrCP / Colorectal cancer / Oncogenic signaling / NF-κB / 非放射性試験管内活性測定法 / インスリン非依存性糖尿病 / アルツハイマー型認知症 / グリコーゲン合成酵素キナーゼ3β(GSK3β) / β-cateninがん化シグナル / がん(化学)予防 / アルツハイマー型認知症(痴呆症) / β-カラニン / 細胞特性 / 分子特性 / 診断 / エネルギー代謝 / 標的治療 / 蛋白質リン酸化 / 胃癌 / 遺伝子発現 / SAGE / STOMACH CANCER / GENE EXPRESSION / SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) / がん遺伝子 / がん化シグナル伝達 / 分子診断 / がん遣伝子 / Oncogene / Molecular diagnosis / がん化シグナル / ユビキチンシステム / ELISA / 血清分子診断 / ユビキチン化分解 / β-TrCP E3ユビキチンリガーゼ / RASがん化シグナル / Ubiquitin system / RNA trans-acting factor / 核移送 / 核膜孔複合体 / 病態 / 食道 / 扁平上皮がん / 発がん / 糖代謝酵素 / ゲノム編集 / 糖代謝改変 / 細胞核分裂 … More
Except Principal Investigator
GSK3β / 抗がん剤 / SNP / 化学療法 / CPT-11 / 大腸がん / 分子標的治療 / 胃十二指腸外科学 / 膵臓癌 / EMT / メチル化 / DNAメチル化 / 胃癌 / ドラッグリポジショニング / GSK3beta / グリオーマ / 遺伝子多型 / β-catenin / 大腸癌 / TGF-β1 / αVβ8 / AUC / Paclitaxel / ポリオウイルス / ポリオウイルス受容体 / 感染様式 / 腸管上皮細胞 / M細胞 / 極性輸送 / 樹状細胞療法 / 白血球減少 / MTD / 樹状細胞 / Docetaxe1 / OK432 / 塩酸ゲムシタビン / GEMCITABINE / 転移・浸潤 / 遊走能 / 遺伝子解析 / 遺伝子診断 / 腹膜播種(癌性腹膜炎) / CXCR4/CXCL12 axis / Amphiregulin / HB-EGF / EGFR ligands / 癌微小環境 / HER4 / 癌性腹膜炎 / CXCR4 / CXCL12 axis / EGF / EGFR / レトロポゾン / LINE-1 / 5-FU / 熱ショック蛋白質 / 癌 / ストレス応答 / 発達障害 / FAM107B (HITS) / がん抑制遺伝子 / FAM107 / 膵臓がん / GSK３β / 化学療法誘導性EMT / 膵臓癌治療薬 / 消化器がん / すい臓がん / Drug repositioning / 医薬品 / 細胞運動 / 細胞増殖 / 薬剤スクリーニング / 分子標的療法 / Akt / Notch / 増殖 / 浸潤 / テモゾロミド / 薬剤感受性 / MGMT / 膠芽腫 / シグナル伝達 / 胃がん / ゲノム / 連鎖解析 / 相関解析 / マイクロサテライト / 罹患同胞対 / 連鎖 / 相関 / 全ゲノムスキャン / マイクロサテライトマーカー / SNPs / 多因子疾患 / 罹患同胞対法 / 全ゲノムスクリーニング / LOD値 / gastric cancer / genome / polymorphism / linkage / association / microsatellite / マトリックスメタロプロテアーゼ / 血管新生 / ベーターカテニン / 癌転移 / 血管新生抑制剤 / 肝転移 / がん転移 / MMP / Tumor dormancy therapy / 転移 / Matrix metalloproteinase / angiogensis / Cancer oteinases metastasis / Angiogenic inhibitor / liver metastasis / インテグリン / β-カテニン / 浸潤・転移 / Integrin / Colorectal cancer / Invasion and metastasis / tailored dose化学療法 / UGT1A1 / 癌化学療法 / 個別化 / 薬剤動態 / tailored dose chemotherapy / Gastric Cancer / がん代謝 / リン酸化 / 幹細胞 / 脳神経疾患 / エクソソーム / 抗癌剤 / 共培養 / 膵がん / HSP90 / 癌細胞 / 食道発癌 / 化学予防 / 大腸鋸歯状腺腫 Less

  • Research Projects

    (33 results)

  • Research Products

    (598 results)

  • Co-Researchers

    (86 People)

  •  GSK3βを基軸とした食道発癌機構の解明と新規治療戦略の開発Ongoing

    • Principal Investigator
      宮下 知治
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kanazawa University

  •  Investigation of molecular pathways linking aberrant glucose metabolism and mitotic process in colorectal cancer and its application to development of cancer therapyPrincipal InvestigatorOngoing

    • Principal Investigator
      源 利成
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kanazawa University

  •  RNAシーケンスによる大腸鋸歯状腺腫の発癌機構の解明と分子標的治療の基盤確立Ongoing

    • Principal Investigator
      太田 亮介
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kanazawa University

  •  代謝酵素ゲノム編集による食道扁平上皮の易発がん状態誘発の試みPrincipal InvestigatorOngoing

    • Principal Investigator
      源 利成
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kanazawa University

  •  Identification and functional analysis of nuclear pore complex components that function to transport beta-catenin between cytoplasm and nucleusPrincipal Investigator

    • Principal Investigator
      Minamoto Toshinari
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Investigation of biological basis of GSK3beta-targeted therapy and its translation to colorectal cancer treatmentPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  The elucidation of the molecular mechanism about the acquisition of pancreatic cancer invasion ability and application to cancer therapy

    • Principal Investigator
      SHIMASAKI Takeo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa Medical University

  •  Drag repositioning for malignant glioma targeting glioma stem cells

    • Principal Investigator
      Nakada Mitsutoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurosurgery
    • Research Institution
      Kanazawa University

  •  Phosphoproteome analysis of colorectal cancer for understanding of tumor biology and its application to development of treatmentPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Exploring biological basis of aberrant energy metabolic property of gastrointestinal cancer toward application to cancer treatment

    • Principal Investigator
      Domoto Takahiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University

  •  Molecular analysis of colorectal cancer with LINE-1 hypomethylation and its application to cancer diagnosis and therapy

    • Principal Investigator
      KAWAKAMI KAZUYUKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokyo Women's Medical University
      Kanazawa University

  •  Expression and functional analysis of FAM107 family proteins as a new molecular marker for the onco-hyperthermia therapy

    • Principal Investigator
      NAKAJIMA Hideo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kumamoto University
      Kanazawa Medical University

  •  Development of the pancreatic cancer therapy by identification of EMT inducer by chemotherapy

    • Principal Investigator
      SHIMASAKI Takeo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa Medical University

  •  Therapeutic effect of the GSK3beta-inhibiting drugs against gastrointestinal cancer and the elucidation of a molecular mechanism

    • Principal Investigator
      HIROSE Mayumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Molecular targeted therapy focusing invasion signaling in malignant glioma cell

    • Principal Investigator
      NAKADA MITSUTOSHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University

  •  Treatment of gastrointestinal cancer by targeting the distinct energy metabolism of cancer cellsPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Molecular basis of aberrant cellular pathways in gastrointestinal cancer and its application to diagnosis and treatmentPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  GSK3βのがん促進機能の分子機構解明とその阻害に基づく消化器がん治療法の開発Principal Investigator

    • Principal Investigator
      源 利成
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University

  •  Mechanistic analysis on DNA methylation in colorectal cancer and its application to diagnosis and therapy

    • Principal Investigator
      KAWAKAMI Kazuyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Development of molecular target therapy for gastric cancer targeted for the CXCR4/CXCL12 axis and HB-EGF

    • Principal Investigator
      YASUMOTO Kazuo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Study of the optimal dose of some chemotherapeutic drugs forenhancement of cancer specific immunotherapy by dendritic cell

    • Principal Investigator
      TAKAHASHI Yutaka
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University

  •  塩酸ゲムシタビンによる膵がん細胞のEMT誘導の検証と分子細胞機構の解明

    • Principal Investigator
      SHIMASAKI Takeo
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa Medical University

  •  Molecular basis of deregulated Wnt signaling in clinical colorectal cancerPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  β-catenin/Tcf複合体の新規転写標的分子の同定と大腸癌における機能解析Principal Investigator

    • Principal Investigator
      源 利成
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Tailored dose chemotherapy and the relationship with PK.

    • Principal Investigator
      TAKAHASHI Yutaka
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  糖代謝調節キナーゼのWntシグナル非依存的がん化作用の解明と大腸癌制御への応用Principal Investigator

    • Principal Investigator
      源 利成
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Relationship between activation of TGF-β1 by αVβ8 integrin and the invasion and metastasis of colorectal cancer

    • Principal Investigator
      KAWASHIMA Atsuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      National Hospital Organization Kanazawa Medical Center (Clinical Research Center)

  •  Activation and regulation of oncogenic signaling networks in colorectal cancerPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  ポリオウイルス感染におけるM細胞の役割の検討

    • Principal Investigator
      OHNO Hiroshi
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University

  •  Distinct Pattern of Oncogenic β-catenin Activation in Colorectal CancerPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  Genome-wide analyses to identify genes involved in gastric cancer

    • Principal Investigator
      SASAZUKI Tekehiko
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      International Medical Center of Japan
      Kyushu University

  •  Molecular insight of cancer metastasis of gastrointestinal tract -strategies of therapeutic implication

    • Principal Investigator
      MAI Masayoshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kanazawa University

  •  SERIAL ANALYSIS OF GENE EXPRESSION (SAGE) IN HUMAN STOMACH CANCERPrincipal Investigator

    • Principal Investigator
      MINAMOTO Toshinari
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KANAZAWA UNIVERSITY

All 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2000 Other

All Journal Article Presentation Book Patent

  • [Book] Colorectal Cancer Biology-From genes to Tumor2012
    • Author(s)
      Minamoto T, et al., Kawakami K
    • Publisher
      nTech Open Access Company
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Book] Colorectal Cancer Biology - From Genes to Tumor2012
    • Author(s)
      Minamoto T
    • Total Pages
      458
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Book] Colorectal Cancer Biology - From Genes to Tumor 12012
    • Author(s)
      Minamoto T
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Book] Colorectal Cancer Biology-From Genes to Tumor2012
    • Author(s)
      Minamoto T, et al, Kawkami K
    • Publisher
      InTech(印刷中)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Book] Colorectal Cancer Biology -From Genes to Tumor2012
    • Author(s)
      Minamoto T, et al, Kawakami K
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Book] Colorectal Cancer Biology - From Genes to Tumor2012
    • Author(s)
      Minamoto T, et al, Kawkami K
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Book] Colorectal Cancer Biology - From Genes to Tumor2012
    • Author(s)
      Minamoto T
    • Total Pages
      458
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Book] Distinct pathologic role for glycogen synthase kinase 3β in colorectal cancer progression2012
    • Author(s)
      Minamoto T, Kotake M, Nakada M, Shimasaki T, Motoo Y, Kawakami K
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Book] RNA Technologies and Their Applications ; Erdmann VA, Barciszewski J, eds. RNAi in malignant brain tumors : relevance to molecular and translational research,分担執筆2011
    • Author(s)
      Nakada M, Kawakami K, et al, Minamoto T
    • Publisher
      Springer Verlag
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Book] Molecular Targets of CNS Tumors2011
    • Author(s)
      Nakada M, Minamoto T et al.
    • Total Pages
      674
    • Publisher
      InTech Open Access Company
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Book] The pivotal role of GSK3β in glioma biology2011
    • Author(s)
      Nakada M, Minamoto T, Pyko IV, Hayashi Y, Hamada JI
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Book] Molecular Targets of CNS Tumors2011
    • Author(s)
      Nakada M, Minamoto T, et al
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Book] Molecular Targets of CNS Tumors2011
    • Author(s)
      Nakada M, Minamoto T, et al.
    • Total Pages
      674
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Book] RNA Technologies and Their Applications2010
    • Author(s)
      Nakada M, Kawakami K, et al, Minamoto T
    • Publisher
      Springer Verlag
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Book] Methods in Molecular Biology / Molecular Toxixology Protocols2005
    • Author(s)
      Minamoto T
    • Total Pages
      489
    • Publisher
      Keohavong P, Grant S, eds., Humana Press
    • Data Source
      KAKENHI-PROJECT-16659354

  • [Book] Methods in Molecular Biology/Molecular Toxixology Protocols(Keohavong P, Grant S, eds.)2005
    • Author(s)
      Minamoto T
    • Total Pages
      489
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Book] Molecular Toxicology Protocols/Methods of Molecular Biology(Keohavong P and Grant S, eds.)2005
    • Author(s)
      Minamoto T
    • Total Pages
      489
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Book] Molecular Toxicology Protocols/Methods of Molecular Biology(Keohavong P and Grant S, eds.)2005
    • Author(s)
      Minamoto T
    • Total Pages
      489
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-16659354

  • [Book] Molecular Toxicology Protocols/Methods of Molecular Biology Vol 2912004
    • Author(s)
      Minamoto T.
    • Total Pages
      489
    • Publisher
      Humana Press(Keohavong P, Grant S, eds.)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Posttranscriptional regulation of BRG1 by FIRΔexon2 in gastric cancer.2020
    • Author(s)
      Ailiken Guzhanuer、Kitamura Kouichi、Hoshino Tyuji、Satoh Mamoru、Tanaka Nobuko、Minamoto Toshinari、Rahmutulla Bahityar、Kobayashi Sohei、Kano Masayuki、Tanaka Tomoaki、Kaneda Atsushi、Nomura Fumio、Matsubara Hisahiro、Matsushita Kazuyuki
    • Journal Title

      Oncogenesis.

      Volume: 9 Pages: 26-26

    • DOI

      10.1038/s41389-020-0205-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KT0019, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-18K07462

  • [Journal Article] Glycogen synthase kinase 3beta as a potential therapeutic target in synovial sarcoma and fibrosarcoma2020
    • Author(s)
      Abe Kensaku、Yamamoto Norio、Domoto Takahiro、Bolidong Dilireba、Hayashi Katsuhiro、Takeuchi Akihiko、Miwa Shinji、Igarashi Kentaro、Inatani Hiroyuki、Aoki Yu、Higuchi Takashi、Taniguchi Yuta、Yonezawa Hirotaka、Araki Yoshihiro、Aiba Hisaki、Minamoto Toshinari、Tsuchiya Hiroyuki
    • Journal Title

      Cancer Science

      Volume: 111 Pages: 429-440

    • DOI

      10.1111/cas.14271

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-16K10850

  • [Journal Article] Anti‐FIR Δexon2, a splicing variant form of PUF 60, autoantibody is detected in the sera of esophageal squamous cell carcinoma2019
    • Author(s)
      Kobayashi S, Hiwasa T, Ishige T, Rahmutulla B, Kano M, Hoshino T, Minamoto T, Shimada H, Nomura F, Matsubara H, Matsushita K.
    • Journal Title

      Cancer Science

      Volume: 4 Pages: 1-10

    • DOI

      10.1111/cas.14024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09004, KAKENHI-PROJECT-16K10520, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-17K15768

  • [Journal Article] NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells.2019
    • Author(s)
      Echizen K, Horiuchi K, Aoki Y, Yamada Y, Minamoto T, Oshima H, and Oshima M.
    • Journal Title

      Oncogene.

      Volume: accepted Pages: 4250-4263

    • DOI

      10.1038/s41388-019-0702-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05616, KAKENHI-PROJECT-19K22558, KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-19H03727

  • [Journal Article] Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma2019
    • Author(s)
      Kitabayashi Tomohiro、Dong Yu、Furuta Takuya、Sabit Hemragul、Jiapaer Shabierjiang、Zhang Jiakang、Zhang Guangtao、Hayashi Yasuhiko、Kobayashi Masahiko、Domoto Takahiro、Minamoto Toshinari、Hirao Atsushi、Nakada Mitsutoshi
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 10049-10049

    • DOI

      10.1038/s41598-019-46454-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-18H02910

  • [Journal Article] Nestin phosphorylation at threonies 315 and 1299 correaltes with proliferation and metastasis of human pancreatic cancer.2017
    • Author(s)
      Matsuda Y, Minamoto T, et al.
    • Journal Title

      Cancer Sci

      Volume: 108 Pages: 354-361

    • DOI

      10.1111/cas.13139

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04928, KAKENHI-PROJECT-15K15493

  • [Journal Article] 膵がんの増殖，浸潤と治療不応性を繋ぐ治療標的GSK3β．2017
    • Author(s)
      島崎猛夫，堂本貴寛，宮下知治，中田光俊，元雄良治，太田哲生，源 利成．
    • Journal Title

      肝胆膵

      Volume: 75 Pages: 769-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Journal Article] Biological basis and clinical study of glycogen synthase kinase-3β-targeted therapy by drug repositioning for glioblastoma2017
    • Author(s)
      Furuta T, Sabit H, Yu D, Miyashita K, Kinoshita M, Uchiyama N, Hayashi Y, Hayashi Y, Minamoto T, Nakada M
    • Journal Title

      Ｏｎｃｏｔａｒｇｅｔ

      Volume: 8 Pages: 22811-22824

    • DOI

      10.18632/oncotarget.15206

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-15K19957, KAKENHI-PROJECT-16K10751, KAKENHI-PROJECT-15K10295, KAKENHI-PROJECT-16K15645, KAKENHI-PROJECT-15H04928

  • [Journal Article] Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin2016
    • Author(s)
      Shimozaki S, Minamoto T, et al.
    • Journal Title

      Oncotarget

      Volume: 7 Pages: 77038-51

    • DOI

      10.18632/oncotarget.12781

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928, KAKENHI-PROJECT-26293333, KAKENHI-PROJECT-15K15493, KAKENHI-PROJECT-16K15658, KAKENHI-PROJECT-16K20042

  • [Journal Article] 有糸分裂期の機能性ヌクレオポリン：大腸がんの病態解明と治療への応用2016
    • Author(s)
      橋爪智恵子，源 利成，Richard Wong.
    • Journal Title

      生化学

      Volume: 88 Pages: 748-51

    • NAID

      120006464083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Journal Article] Glycogen synthase kinase-3beta is a pivotal mediator of cancer invasion and resistance to therapy2016
    • Author(s)
      Domoto T, et al, Minamoto T.
    • Journal Title

      Cancer science

      Volume: 107 Pages: 1363-1372

    • DOI

      10.1111/cas.13028

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-15K15493, KAKENHI-PROJECT-16K19996

  • [Journal Article] 抗がん剤により膵癌細胞に誘導されるＥＭＴ促進因子の同定と機能解析2016
    • Author(s)
      島崎猛夫、山本聡子、石垣靖人、高田尊信、有沢富康、元雄良治、友杉直久、源利成
    • Journal Title

      膵臓

      Volume: 31 Pages: 76-84

    • NAID

      130005137841

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Journal Article] 有糸分裂期の機能性ヌクレオポリン：大腸がんの病態解明と治療への応用2016
    • Author(s)
      橋爪智恵子，源 利成，Richard Wong
    • Journal Title

      生化学

      Volume: 88 Pages: 748-51

    • NAID

      120006464083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Journal Article] Long interspersed nucleotide element-1 methylation: a determinant of response to chemotherapy and prognosis in advanced-stage colorectal cancer.2016
    • Author(s)
      Kaneko M, et al., Minamoto T.
    • Journal Title

      BMC Cancer

      Volume: 16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Journal Article] Long interspersed nucleotide element-1 methylation: a determinant of response to chemotherapy and prognosis in advanced-stage colorectal cancer.2016
    • Author(s)
      Kaneko M, et al., Minamoto T.
    • Journal Title

      BMC Cancer

      Volume: 16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Journal Article] Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.2016
    • Author(s)
      Menheniott TR, Minamoto T, et al.
    • Journal Title

      J Clin Invest

      Volume: 126 Pages: 1383-400

    • DOI

      10.1172/jci82655

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928, KAKENHI-PROJECT-15K15493

  • [Journal Article] Glycogen synthase kinase 3beta sustains invasion of glioblastoma via the focal adhesion kinase, Rac1 and c-Jun N-terminal kinase-mediated pathway.2015
    • Author(s)
      Chikano Y, Domoto T, Furuta T, Sabit H, Kitano-Tamura A, Ilya V. Pyko, Takino T, Sai Y, Hayashi Y, Sato H, Miyamoto K, Nakada M, MinamotoT.
    • Journal Title

      Mol Cancer Ther

      Volume: 14 Pages: 564-574

    • DOI

      10.1158/1535-7163.mct-14-0479

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460382, KAKENHI-PROJECT-25670572, KAKENHI-PROJECT-25860233, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-26670638, KAKENHI-PROJECT-26893096, KAKENHI-PROJECT-15K15493, KAKENHI-PROJECT-15H04928

  • [Journal Article] Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer.2015
    • Author(s)
      Kurklu B, Minamoto T, et al.
    • Journal Title

      Oncogene

      Volume: 印刷中 Pages: 2856-2866

    • DOI

      10.1038/onc.2014.233

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25670572, KAKENHI-PROJECT-15K15493, KAKENHI-PROJECT-15H04928

  • [Journal Article] TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells2014
    • Author(s)
      Oshima H, Ishikawa T, Yoshida GJ, Naoi K, Maeda Y, Naka K, Ju X, Yamada Y, Minamoto T, Mukaida N, Saya H, Oshima M.
    • Journal Title

      Oncogene

      Volume: 33 Pages: 1-10

    • DOI

      10.1038/onc.2013.356

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22114005, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24300325, KAKENHI-PROJECT-24501314, KAKENHI-PROJECT-25430107, KAKENHI-PROJECT-25670572

  • [Journal Article] 多機能キナーゼGSK3βを標的とした膠芽腫治療2014
    • Author(s)
      中田光俊、源利成
    • Journal Title

      癌と化学療法

      Pages: 41-41

    • Data Source
      KAKENHI-PROJECT-23592117

  • [Journal Article] Detection and characterization of oncogene mutations in preneoplastic and early neoplastic lesions2014
    • Author(s)
      Minamoto T.
    • Journal Title

      Methods in Molecular Biology

      Volume: 1105 Pages: 381-398

    • DOI

      10.1007/978-1-62703-739-6_29

    • NAID

      120000813359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Journal Article] Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?2013
    • Author(s)
      Loh M, Kawakami K, Minamoto T, et al
    • Journal Title

      Pharmacogenomics J 2012

      Volume: (in press) Pages: 423-429

    • DOI

      10.1038/tpj.2012.26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-25670572

  • [Journal Article] GSK3β阻害作用を持つ医薬品を用いた難治性膵癌の新規治療法の開発2013
    • Author(s)
      島崎猛夫、上田順彦、源利成
    • Journal Title

      がん治療のあゆみ

      Volume: 第33巻

    • Data Source
      KAKENHI-PROJECT-23591016

  • [Journal Article] Aberrant glycogen synthase kinase 3β in pancreatic cancer development, progression and resistance to therapy2013
    • Author(s)
      Shimasaki T, Kitano A, Motoo Y, Minamoto T
    • Journal Title

      J Carcinog

      Volume: 11 Pages: 15-15

    • DOI

      10.4103/1477-3163.100866

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23659643

  • [Journal Article] Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy2013
    • Author(s)
      Kitano A, et al, Kawakami K, Minamoto T
    • Journal Title

      PLoS One

      Volume: 8(2)

    • NAID

      120005253831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Aberrant glycogen synthase kinase 3beta in pancreatic cancer development, progression and resistance to therapy2013
    • Author(s)
      Shimasaki T, Kitano A, Motoo Y, Minamoto T
    • Journal Title

      J Carcinog

      Volume: 11巻

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Journal Article] Inhibition of angiopoietin 2 attenuates lumen formation of tumour-associated vessels in vivo.2013
    • Author(s)
      Suzuki R et al.
    • Journal Title

      Int J Oncol

      Volume: 43 Pages: 1447-55

    • DOI

      10.3892/ijo.2013.2076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390315, KAKENHI-PROJECT-25670572

  • [Journal Article] Aberrant glycogen synthase kinase 3 beta is involved in pancreatic cancer cell invasion and resistance to therapy2013
    • Author(s)
      Kitano ., Shimasaki T, Chikano Y, Nakada M, Hirose M, Higashi T, Ishigaki Y, Endo Y, Takino T, Sato H, Sai Y, Miyamoto K, Motoo Y, Minamoto T
    • Journal Title

      PLoS One

      Volume: 8巻

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Journal Article] Aberrant glycogen synthase kinase 3β is involved in pancreatic2013
    • Author(s)
      Kitano A
    • Journal Title

      PloS One

      Volume: 8 Pages: 1-12

    • DOI

      10.1371/journal.pone.0055289

    • URL

      http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-22790542, KAKENHI-PUBLICLY-23120703, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23590356, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-25460793, KAKENHI-PROJECT-25670572

  • [Journal Article] Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy2013
    • Author(s)
      Kitano A, Shimasaki T, Chikano Y, Nakada M, Hirose M, Higashi T, Ishigaki Y, Endo Y, Takino T, Sato H, Sai Y, Miyamoto KI, Motoo Y, Kawakami K, Minamoto T
    • Journal Title

      PLoS One

      Volume: 8(2)

    • NAID

      120005253831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Journal Article] Aberrant glycogen synthase kinase 3βis involved in pancreatic cancer cell invasion and resistance to therapy2013
    • Author(s)
      Kitano A, Shimasaki T, Chikano Y, Nakada M, Hirose M, Higashi T, Ishigaki Y, Endo Y, Takino T, Sato H, Sai Y, Miyamoto K, Motoo Y, Kawakami K, Minamoto T.
    • Journal Title

      PLoS One

      Volume: 8(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Journal Article] Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling.2013
    • Author(s)
      Pyko IV, Nakada M, Sabit H, Teng L, Furuyama N, Hayashi Y, Kawakami K, Minamoto T, Fedulau AS, Hamada J
    • Journal Title

      Carcinogenesis

      Volume: 34 Pages: 2206-17

    • DOI

      10.1093/carcin/bgt182

    • URL

      http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-25670572

  • [Journal Article] Glycogen synthase kinase 3βinhibition sensitizes pancreatic cancer cells to gemcitabine2012
    • Author(s)
      Shimasaki T, Ishigaki Y, Nakamura Y, Takata T, Nakaya N, Nakajima H, Sato I, Zhao X, Kitano A, Kawakami K, Tanaka T, Takegami T, Tomosugi N, Minamoto T, Motoo Y.
    • Journal Title

      J Gastroenterol

      Volume: 47(3) Pages: 321-33

    • NAID

      10030560208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Journal Article] The strategy for enhancing temozolomide against malignant glioma2012
    • Author(s)
      Nakada M
    • Journal Title

      Frontiers in Radiation Oncology

      Volume: 2 Pages: 98-98

    • DOI

      10.3389/fonc.2012.00098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-23659643

  • [Journal Article] LINE-1 methylation shows little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer.2012
    • Author(s)
      Matsunoki A, Kawakami K, et al, Minamoto T
    • Journal Title

      BMC Cancer.

      Volume: 12 Pages: 574-574

    • DOI

      10.1186/1471-2407-12-574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643

  • [Journal Article] 5.Glycogen synthase kinase 3beta inhibition sensitizes pancreatic cancer cells to gemcitabine2012
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et al
    • Journal Title

      Journal of Gastroenterology

      Volume: 47 (3) Pages: 321-33

    • DOI

      10.1007/s00535-011-0484-9

    • URL

      http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23591016, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643

  • [Journal Article] Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells2012
    • Author(s)
      H. Nakajima, Y. Ishigaki, QS. Xia, T. Ikeda, Y. Yoshitake, H. Yonekura, T. Nojima, T. Tanaka, H. Umehara, N. Tomosugi, T. Takata, T. Shimasaki, N. Nakaya, I. sato, K. Kawakami, K. Koizumi, T. Minamoto, Y. Motoi
    • Journal Title

      Molecular Vision

      Volume: 37 Pages: 1347-1357

    • DOI

      10.3892/ijo_00000707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590389, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23590898, KAKENHI-PROJECT-23792017

  • [Journal Article] AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene2012
    • Author(s)
      Mimura, M., et al
    • Journal Title

      Int J Cancer

      Volume: 130 Pages: 1011-1020

    • DOI

      10.1002/ijc.26131

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113003, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23659643

  • [Journal Article] Inflammation-induced repression of tumor suppressor miR-7 1n gastrictumor cells2012
    • Author(s)
      Kong D, Piao YS, Yamashita S, Oshima H, Oguma K, Fushida S, Fujimura T, Minamoto T, Seno H, Yamada Y, Satou K, Ushijima T, Ishikawa T, and Oshima M.
    • Journal Title

      Oncogene

      Volume: (in press) Pages: 3949-3960

    • DOI

      10.1038/onc.2011.558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390118, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22500996, KAKENHI-PROJECT-22800025, KAKENHI-PROJECT-23659643, KAKENHI-PROJECT-24300325, KAKENHI-PLANNED-22114005

  • [Journal Article] Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis2012
    • Author(s)
      Nakajima H, Koizumi K, Tanaka T, Ishigaki Y, Yoshitake Y, Yonekura H, Sakuma T, Fukushima T, Umehara H, Ueno S, Minamoto T and Motoo Y
    • Journal Title

      Int J Oncol 2012

      Volume: 41 Pages: 1347-1357

    • DOI

      10.3892/ijo.2012.1550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249041, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23500427, KAKENHI-PROJECT-23590349, KAKENHI-PROJECT-23590898, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643

  • [Journal Article] Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing2011
    • Author(s)
      Tomita H, Kawakami K, Minamoto T, et al.
    • Journal Title

      Gastroenterology

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Long interspersed nuclear element-1 hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CpG island methylator phenotype-negative colorectal cancer2011
    • Author(s)
      Kawakami K, et al, Minamoto T
    • Journal Title

      Cancer Science

      Volume: (印刷中)

    • NAID

      10029288925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFFI epigenetic silencing2011
    • Author(s)
      Tomita H, Kawakami K, Minamoto T, et al.
    • Journal Title

      Gastroenterology

      Volume: 140 Pages: 879-891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Metabolic disorder, inflammation and deregulated molecular pathways converging in pancreatic cancer development: implications for new therapeutic strategies2011
    • Author(s)
      Motoo Y, et al, Minamoto T
    • Journal Title

      Cancers (Basel)

      Volume: 3(1) Pages: 446-460

    • DOI

      10.3390/cancers3010446

    • NAID

      120003141569

    • URL

      http://www.kanazawa-u.ac.jp/~ganken/shuyoseigyo/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-23591955, KAKENHI-PROJECT-23659643

  • [Journal Article] Long interspersed nuclear element-I hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CnG island methvlator phenotype-negative colorectal cancer2011
    • Author(s)
      Kawakami_K, et al, Minamoto T
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 166-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing2011
    • Author(s)
      Tomita H, Kawakami K, Minamoto T, et al
    • Journal Title

      Gastroenterology

      Volume: 140 (3) Pages: 879-891

    • DOI

      10.1053/j.gastro.2010.11.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23590919, KAKENHI-PROJECT-23659643

  • [Journal Article] Long interspersed nuclear element-1 hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CpG island methylator phenotype-negative colorectal cancer2011
    • Author(s)
      Kawakami K, et al, Minamoto T
    • Journal Title

      Cancer Science

      Volume: 102(1) Pages: 166-174

    • DOI

      10.1111/j.1349-7006.2010.01776.x

    • NAID

      10029288925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23659643

  • [Journal Article] Long interspersed nuclear element-1 hypomethylation is a potential biomarker for the prediction of response to oral fluoropyrimidines in microsatellite stable and CpG island methylator phenotype-negative colorectal cancer.2011
    • Author(s)
      Kawakami K, (他4名), Minamoto T.
    • Journal Title

      Cancer Sci 102

      Pages: 166-174

    • NAID

      10029288925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] LINE-1 hypomethylation is a poor prognostic factor in stage IA non-small cell lung cancer.2010
    • Author(s)
      Saito K, Kawakami K, et al., Minamoto T.
    • Journal Title

      Clinical Cancer Research (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer.2010
    • Author(s)
      Saito K, Kawakami K (他3名), Minamoto T.
    • Journal Title

      Clin Cancer Res 16

      Pages: 2418-2426

    • NAID

      120002205532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] RNAi in malignant brain tumors : relevance to molecular and translational research.2010
    • Author(s)
      Nakada M, Kawakami K, et al., Minamoto T.
    • Journal Title

      Erdmann VA, Barciszewski J, eds., RNA Technologies and Their Applications, Springer Verlag (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.2010
    • Author(s)
      Peterson AJ, Kawakami K, Minamoto T, (他8名).
    • Journal Title

      Gastroenterology 139

      Pages: 2005-2017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Long interspersed nuclear element I hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer2010
    • Author(s)
      Saito K, Kawakami K, et al, Minamoto T
    • Journal Title

      Clinical Cancer Research

      Volume: 16 Pages: 2418-2426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans2010
    • Author(s)
      Peterson AJ, Kawakami K, Minamoto T, et al.
    • Journal Title

      Gastroenterology

      Volume: 139 Pages: 2005-2017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage lA non-small cell lung cancer2010
    • Author(s)
      Saito K, Kawakami K, et al, Minamoto T
    • Journal Title

      Clinical Cancer Research

      Volume: 16 Pages: 2418-2426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer2010
    • Author(s)
      Saito K, Kawakami K, et al, Minamoto T
    • Journal Title

      Clin Cancer Res

      Volume: 16 (8) Pages: 2418-26

    • DOI

      10.1158/1078-0432.ccr-09-2819

    • NAID

      120002205532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Induction of HITS, a newly identified family with sequence similarity 107 protein(FAM107B), in cancer cells by heat shock stimulation.2010
    • Author(s)
      Nakajima H, Kawakami K, et al, Minamoto T
    • Journal Title

      International Journal of Oncology

      Volume: 37 Pages: 583-593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans2010
    • Author(s)
      Peterson AJ, Kawakami K, Minamoto T, et al.
    • Journal Title

      Gastroenterology

      Volume: 139 Pages: 2005-2017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans2010
    • Author(s)
      Peterson AJ, Kawakami K, Minamoto T, et al
    • Journal Title

      Gastroenterology

      Volume: 139 (6) Pages: 2005-17

    • DOI

      10.1053/j.gastro.2010.08.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Journal Article] Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation.2010
    • Author(s)
      Nakajima H, Kawakami K, et al, Minamoto T
    • Journal Title

      International Journal of Oncology

      Volume: 37 Pages: 583-593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Gemcitabine changes the gene expression in human pancreatic cancer cells : search for new therapeutic molecular targets.2009
    • Author(s)
      Motoo Y, et al, Minamoto T
    • Journal Title

      Basic, Clinical and Surgical Pancreatology, Proceedings of the NATO Advanced ResearchWorkshop on Pancreatology : from Bench toBedside 印刷中(掲載確定)

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2009
    • Author(s)
      Miyashita K, Kawakami K, et.al, Minamoto T
    • Journal Title

      Clinical Cancer Research 15

      Pages: 887-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Deregulated glycogen synthase kinase 3β sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.2009
    • Author(s)
      Mai W, Kawakami K, (他7名), Minamoto T.
    • Journal Title

      Clin Cancer Res 15

      Pages: 6810-6819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.2009
    • Author(s)
      Jin MJ, Kawakami K, et al., Minamoto T.
    • Journal Title

      Cancer Science 100

      Pages: 2325-2330

    • NAID

      10027198108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GUI1 mRNA.2009
    • Author(s)
      Noubissi FK, Kawakami K, Minamoto T, et al.
    • Journal Title

      Cancer Research 69

      Pages: 8572-8578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Deregulated glycogen synthase kinase 3β sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.2009
    • Author(s)
      Mai W, Kawakami K, Shimasaki T, et al., Minamoto T.
    • Journal Title

      Clinical Cancer Research 15

      Pages: 6810-6819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition againsthuman glioblastoma.2009
    • Author(s)
      Miyashita K, Kawakami K, et al., Minamoto T.
    • Journal Title

      Clinical Cancer Research 15

      Pages: 887-897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Deregulated glycogen synthase kinase 3β sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase2009
    • Author(s)
      Mai W, Kawakami K, Minamoto T, et al
    • Journal Title

      Clinical Cancer Research 15

      Pages: 6810-6819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] The IL-6 family cytokine IL-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development2009
    • Author(s)
      Howled M, Minamoto T, et.al.
    • Journal Title

      Gastroenterology 136

      Pages: 967-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] The IL-6 family cytokine IL-11 regulates homeostatic epithelial cellturnover and promotes gastric tumor development.2009
    • Author(s)
      Howlett M, Minamoto T, et al.
    • Journal Title

      Gastroenterology 136

      Pages: 967-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3β2009
    • Author(s)
      Miyashita K, Kawakami K, Minamoto T, et al
    • Journal Title

      Anti-Cancer Agents Med Chem 9

      Pages: 1114-1122

    • NAID

      120001856980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2009
    • Author(s)
      Miyashita K, Kawakami K, Nakada M, Mai W, Shakoori A, Shakoori A, Hayashi Y, Hamada J, Minamoto T.
    • Journal Title

      Clin Cancer Res 15(3)

      Pages: 887-897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Induction and downregulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis.2009
    • Author(s)
      Du YC, Minamoto T, et al.
    • Journal Title

      Gastroenterology 137

      Pages: 1346-1357

    • NAID

      120001643242

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA2009
    • Author(s)
      Noubissi FK, Kawakami K, Minamoto T, et al
    • Journal Title

      Cancer Research 69

      Pages: 8572-8578

    • NAID

      120001856981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels2009
    • Author(s)
      Jin MJ, Kawakami K, Minamoto T, et al
    • Journal Title

      Cancer Science 100

      Pages: 2325-2330

    • NAID

      10027198108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.2009
    • Author(s)
      Jin MJ, Kawakami K, (他6名), Minamoto T.
    • Journal Title

      Cancer Sci 100

      Pages: 2325-2330

    • NAID

      10027198108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Gemcitabine changes the gene expression in human pancreatic cancer cells : search for new therapeutic molecular targets2009
    • Author(s)
      Motoo Y, et.al, Minamoto T
    • Journal Title

      Basic, Clinical and Surgical Pancreatology, Proceedings of the NATO Advanced Research Workshop on Pancreatology : from Bench to Bedside (印刷中)(掲載確定)

    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] The IL-6 family cytokine IL-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development2009
    • Author(s)
      Howlett M, Giraud AS, Lescesen H, Jackson CB, Kalantzis A, van Driel IR, Robb L, Van der Hoek M, Minamoto T, Boussioutas A, Oshima H, Oshima M, Judd LM.
    • Journal Title

      Gastroenterology 136(3)

      Pages: 967-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Potential therapeutic effect of glycogen synthase kinase 3βinhibition against human glioblastoma.2009
    • Author(s)
      Miyashita K, Kawakami K, etal, Minamoto T
    • Journal Title

      Clinical Cancer Research 15

      Pages: 887-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] The IL-6 family cytokine IL-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development.2009
    • Author(s)
      Howlett M, Minamoto T, et al.
    • Journal Title

      Gastroenterology 136

      Pages: 967-977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3β.2009
    • Author(s)
      Miyashita K, Shimasaki T, et al., Kawakami K, Minamoto T.
    • Journal Title

      Anti-Cancer Agents in Medicinal Chemistry 9

      Pages: 1114-1122

    • NAID

      120001856980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Low expression of gamma glutamyl hydrolase mRNA in pimary colorectal cancer with the CpG island methvlator phenotype.2008
    • Author(s)
      Kawakami K, et. al., Minamoto T.
    • Journal Title

      British Journal of Cancer (印刷中)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Expression of NLRP7 (PYPAF3, NALP7) protein in endometrial cancer tissues2008
    • Author(s)
      Ohno S, Minamoto T, et.al.
    • Journal Title

      Anticancer Research 28

      Pages: 2493-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Wnt/β-カテニンシグナル制御破綻の新しい分子メカニズム-大腸がん医療との関連-2008
    • Author(s)
      山下要, 川上和之, 源利成
    • Journal Title

      Biothelapy 22

      Pages: 287-95

    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] 大腸がんの診断と検診を目指す便の細胞・分子マーカー検出の試み.2008
    • Author(s)
      源利成, ほか, 川上和之
    • Journal Title

      臨床消化器内科 23

      Pages: 183-89

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] 大腸がんの診断と検診を目指す便の細胞・分子マーカー検出の試み2008
    • Author(s)
      源利成, ほか, 川上和之
    • Journal Title

      臨床消化器内科 23

      Pages: 183-89

    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Low expression of y-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype2008
    • Author(s)
      Kawakami K., et.al., Minamoto T
    • Journal Title

      British Journal of Cancer 98

      Pages: 1555-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Journal Article] Expression of NLRP7 (PYPAF3, NALP7)protein in endometrial cancer tissues.2008
    • Author(s)
      Ohno s, Minamoto T, et al.
    • Journal Title

      Anticancer Research 28

      Pages: 2493-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Low expression of γ-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype2008
    • Author(s)
      Kawakami K, Ooyama A, Ruszkiewicz A, Jin M, Watanabe G, Moore J, Oka T, Iacopetta B, Minamoto T.
    • Journal Title

      Br J Cancer 98(9)

      Pages: 1555-61

    • NAID

      120000806597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Low expression of γ-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.2008
    • Author(s)
      Kawakami K., et al, Minamoto T
    • Journal Title

      British Journal of Cancer 98

      Pages: 1555-61

    • NAID

      120000806597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Low expression of γ-glutamyl hydrolase mRNA in primarycolorectal cancer with the CpG island methylator phenotype2008
    • Author(s)
      Kawakami K, Minamoto T, et al
    • Journal Title

      British Journal of Cancer 98

      Pages: 1555-1561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Low expression of γ -glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.2008
    • Author(s)
      Kawakami K, (他7名), Minamoto T.
    • Journal Title

      Br J Cancer 98

      Pages: 1555-1561

    • NAID

      120000806597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Journal Article] Wnt/β-カテニンシグナル制御破綻の新しい分子メカニズムー大腸がん医療との関連-2008
    • Author(s)
      山下要, 川上和之, 源利成
    • Journal Title

      Biotherapy 22

      Pages: 287-95

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in relation to oncogenic β-catenin activation.2007
    • Author(s)
      Yamashita K, Takahashi Y., et. al., Minamoto T.
    • Journal Title

      Diseases of the Colon & Rectum 50

      Pages: 1169-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Detection ofactive fraction of GSK3β in cancer cells by nonradioisotopic in vitro kinase assay2007
    • Author(s)
      Mai W, et. al., Takahashi Y, Kawakami K. Minamoto T.
    • Journal Title

      Oncology(註:2007年7月に掲載) 71

      Pages: 297-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay.2007
    • Author(s)
      Mai W, Takahashi Y, Kawakami K, Minamoto T
    • Journal Title

      Oncology (印刷中)

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay.2007
    • Author(s)
      Mai W, Takahashi Y, Kawakami K, Minamoto T
    • Journal Title

      Oncology (印刷中)

    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents.2007
    • Author(s)
      Shakoori A, et. al., Takahashi Y, Kawakami K, Minamoto T.
    • Journal Title

      Cancer Science 98

      Pages: 1388-93

    • NAID

      10019998582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in elation to oncogenic β-catenin activation.2007
    • Author(s)
      Yamashita K, et al., Takahashi Y, Minamoto T
    • Journal Title

      Diseases of the Colon and Rectum 50

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancercells in rodents2007
    • Author(s)
      Shakoori A, et. al., Takahashi Y, Kawakami K, Minamoto T.
    • Journal Title

      Cancer Science 98

      Pages: 1388-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Inhibition of GSK-3β activity attenuates proliferation of human colon cancer cells in rodents2007
    • Author(s)
      Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K, Minamoto T.
    • Journal Title

      Cancer Sci 98(9)

      Pages: 1388-93

    • NAID

      10019998582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Methylation levels of LINE-1 repeats and CpG island loci are are inversely related in normal colonic mucosa2007
    • Author(s)
      Iacopetta B, Grieu F, Phillips M, Ruszkiewicz A, Moore J, Minamoto T, Kawakami K.
    • Journal Title

      Cancer Sci 98(9)

      Pages: 1454-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa.2007
    • Author(s)
      Iacopetta B, et. al., Minamoto T. Kawakami K
    • Journal Title

      Cancer Science 98

      Pages: 1454-60

    • NAID

      10019998960

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in relation to oncogenic β-catenin activation2007
    • Author(s)
      Yamashita K, Ougolkov A, Nakazato H, Ito K, Ohashi Y, Kitakata H, Yasumoto K, Omote K, Mai M, Takahashi Y, Minamoto T.
    • Journal Title

      Dis Colon Rectum 50(8)

      Pages: 1169-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in elation to oncogenic β-catenin activation.2007
    • Author(s)
      Yamashita K, et al., Takahashi Y, Minamoto T
    • Journal Title

      Diseases of the Colon and Rectum 50

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Methylation levels of LINE-l repeats and CpG island loci are inversely relatedin normal colnic mucosa2007
    • Author(s)
      Iacopetta B, et. al., Minamoto T, Kawakami K
    • Journal Title

      Cancer Science 98

      Pages: 1454-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Inhibition of GSK3|*beta*|activity attenuates proliferation of humancolon cancer cells in rodents2007
    • Author(s)
      Shakoori A, Mai W Miyashita K, YasumotoK, Takahashi Y, Ooi A, Kawakami K,Minamoto T.
    • Journal Title

      CancerScience 98

      Pages: 1388-1393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591536

  • [Journal Article] Adjuvant immunochemotherapy with protein-bound polysaccharide K forcolon cancer in relation to oncogenic β-catenin activation2007
    • Author(s)
      Yamashita K Takahashi Y, et. al. Minamoto T.
    • Journal Title

      Diseases ofthe Colon & Rectum 50

      Pages: 1169-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] AdjuvantImmunochemotherapy with Protein-boundPolysaccharide K for Colon Cancer inRelation to Oncogenic beta-catenin Activation2007
    • Author(s)
      Yamashita K, Nakazato H, Ito K, OugolkovAV, Kitakata H, Yasumoto K, Omote K, MaiM, Takahashi Y, Minamoto T
    • Journal Title

      Diseases of Colon and Rectum 50

      Pages: 1182-1187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591536

  • [Journal Article] 消化器がんの新しい治療標的2007
    • Author(s)
      源利成・島崎猛夫, 他
    • Journal Title

      消化器科 44巻

      Pages: 468-467

    • Data Source
      KAKENHI-PROJECT-19659190

  • [Journal Article] Detection of active fraction of GSK3β in cancer cells by nonladioisotopic invitro kinase assay.2006
    • Author(s)
      Mai W, et. al., Takahashi Y, Kawakami K, Minamoto T.
    • Journal Title

      Oncology(註:2007年7月に掲載) 71

      Pages: 297-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection.2006
    • Author(s)
      Maenaka S, Minamoto T, et al.
    • Journal Title

      Oncology Report 15・4

      Pages: 791-795

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection.2006
    • Author(s)
      Maenaka S, Hikichi T, Imai-Akasofu M, Minamoto T, Kawahara E.
    • Journal Title

      Oncol Rep (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signaling2006
    • Author(s)
      Noubissi F, Elcheva I, Bhatia N, Shakoori A, Ougolkov A, Liu J, Minamoto T, Ross J, Fuchs SY Spiegelman VS.
    • Journal Title

      Nature 411

      Pages: 898-901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Effect of gemcitabine on the expression of apoptosis-related genes in human pancreatic cancer cells2006
    • Author(s)
      Jiang PH, Motoo Y, Sawabu N, Minamoto T.
    • Journal Title

      World J Gastroenterol 12(10)

      Pages: 1597-602

    • NAID

      120000807303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Effect of adjuvant immunochemotherapy with Coriolus versicolor mycelium-derived polysccharide K for colon cancer with oncogine beta-catenin activation.2006
    • Author(s)
      Yamashita K, Nakazato H, Ito K, Ougolkov AV, Kitakata H, Yasumoto K, Omote K, Mai M, Takahashi Y, Minamoto T.
    • Journal Title

      Diseases of Colon and Rectumjn press. 66

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591382

  • [Journal Article] CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signaling.2006
    • Author(s)
      Noubissi F, Minamoto T, et al.
    • Journal Title

      Nature 441・7095

      Pages: 898-901

    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signaling.2006
    • Author(s)
      Noubissi F, Minamoto T, et al.
    • Journal Title

      Nature 441・7095

      Pages: 898-901

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] c-kit gene mutation is common and widely distributed in intracranial germinomas.2006
    • Author(s)
      Kamakura Y, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery 104・3 Suppl

      Pages: 173-180

    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] c-kit gene mutation is common and widely distributed in intracranial germinomas2006
    • Author(s)
      Kamakura Y, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] c-kit gene mutation is common and widely distributed in intracranial germinomas2006
    • Author(s)
      Kamakura Y, Hasegawa M, Kida S, Tachibana O, Okamoto Y, Minamoto T, Yamashita J, Fujisawa H.
    • Journal Title

      J Neurosurg(3 Suppl Pediatrics) 104

      Pages: 173-180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] c-kit gene mutation is common and widely distributed in intracranial germinomas2006
    • Author(s)
      Kamakura Y, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery (印刷中)

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Effect of gemcitabine on the expression of apoptosis-related genes in human pancreatic cancer cells.2006
    • Author(s)
      Jiang PH, et al., Minamoto T
    • Journal Title

      World Journal of Gastroenterology 12・10

      Pages: 1597-602

    • NAID

      120000807303

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection2006
    • Author(s)
      Maenaka S, Minamoto T, et al.
    • Journal Title

      Oncology Report (印刷中)

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Detection of active fraction of GSK3β in cancer cells by nonradioisotopic in vitro kinase assay2006
    • Author(s)
      Mai W, Miyashita K, Shakoori A, Zhang B, Yu ZW, Takahashi Y, Motoo Y, Kawakami K, Minamoto T.
    • Journal Title

      Oncology 71(3-4)

      Pages: 297-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection.2006
    • Author(s)
      Maenaka S, Minamoto T, et al.
    • Journal Title

      Oncology Report 15・4

      Pages: 791-795

    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection2006
    • Author(s)
      Maenaka S, Minamoto T, et al.
    • Journal Title

      Oncology Report (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] c-kit gene mutation is common and widely distributed in intracranial germinomas.2006
    • Author(s)
      Kamakura Y, Hasegawa M, Kida S, Tachibana O, Okamoto Y, Minamoto T, Yamashita J, Fujisawa H.
    • Journal Title

      J Neurosurg (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Effect of gemcitabine on the expression of apoptosis-related genes in human pancreatic cancer cells.2006
    • Author(s)
      Jiang PH, et al., Minamoto T
    • Journal Title

      World Journal of Gastroenterology 12・10

      Pages: 1597-1602

    • NAID

      120000807303

    • Data Source
      KAKENHI-PROJECT-18659380

  • [Journal Article] c-kit gene mutation is common and widely distributed in intracranial germinomas.2006
    • Author(s)
      Kamakura Y, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery 104・3 Suppl

      Pages: 173-180

    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population2005
    • Author(s)
      Aoki M, Minamoto T, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 335・2

      Pages: 566-574

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Adhesiveness of β5 integrin variant lacking FNK^<767-769> is similar to that of the prototype containing FNKFNK^<767-769>2005
    • Author(s)
      Kawahara E, Minamoto T, et al.
    • Journal Title

      Cell Biology International 29・7

      Pages: 521-528

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] A full genome scan for gastric cancer.2005
    • Author(s)
      Aoki M, Minamoto T, et al.
    • Journal Title

      Journal of Medical Genetics 42・1

      Pages: 83-87

    • NAID

      120001130409

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Detection and characterization of oncogene mutations in preneoplastic and early neoplastic lesions : K-ras oncogene in non-ncoplastic tissue and aberrant crypt foci of colorectal cancer patients.2005
    • Author(s)
      Minamoto T.
    • Journal Title

      Molecular Toxicology Protocols/Methods of Molecular Biology (Keohavong P and Grant S, eds.)(Humana Press, Totawa, NJ) Vol.291

      Pages: 263-278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Deregulated GSK3β activity in colorectal cancer : its association with tumor cell survival and proliferation.2005
    • Author(s)
      Shakoori A, Ougolkov A, Yu ZW, Zhang B, Modarressi MH, Billadeau DD, Mai M, Takahashi Y, Minamoto T.
    • Journal Title

      Biochem Biophys Res Commun 334(4)

      Pages: 1365-1373

    • NAID

      120000812884

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Oncogenic β-catenin signaling network in colorectal cancer.2005
    • Author(s)
      Fuchs SY, et al. Minamoto T
    • Journal Title

      Cell Cycle (印刷中)

    • NAID

      120000812645

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Deregulated GSK3β activity in colorectal cancer : its association with tumor cell survival and proliferation2005
    • Author(s)
      Shakoori A, et al., Takahashi Y, Minamoto T
    • Journal Title

      Biochemical and Biophysical Research Communications 334・4

      Pages: 1365-1373

    • NAID

      120000812884

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population.2005
    • Author(s)
      Aoki M, Yamamoto K, Ohyama S, Yamamura Y, Takenoshita S, Sugano K, Minamoto T, Kitajima M, Sugimura H, Shimada S, Noshiro H, Hiratsuka M, Sairenji M, Ninomiya I, Yano M, Uesaka K, Matsuno S, Maehara Y, Aikou T, Sasazuki T.
    • Journal Title

      Biochem Biophys Res Commun 335(2)

      Pages: 566-574

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Deregulated GSK3β activity in colorectal cancer : its association with tumor cell survival and proliferation2005
    • Author(s)
      Shakoori A, ct al., Takahashi Y, Minamoto T.
    • Journal Title

      Biochemical and Biophysical Research Communications 334・4

      Pages: 1365-1373

    • NAID

      120000812884

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Oncogenic β-catenin signaling network in colorectal cancer.2005
    • Author(s)
      Fuchs SY, et al.Minamoto T
    • Journal Title

      Cell Cycle (印刷中)

    • NAID

      120000812645

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Correlation of γ-catenin expression with good prognosis in medulloblastomas.2005
    • Author(s)
      Misaki K, Marukawa K, Hayashi Y, Fukusato T, Minamoto T, Hasegawa M, Yamashita J, Fujisawa H.
    • Journal Title

      J Neurosurg (Pediatrics 2) 102

      Pages: 197-206

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] A full genome scan for gastric cancer2005
    • Author(s)
      Aoki M, Minamoto T, et al.
    • Journal Title

      Journal of Medical Genetics 42・1

      Pages: 83-87

    • NAID

      120001130409

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Correlation of γ-catenin expression with good prognosis in medulloblastomas2005
    • Author(s)
      Misaki K, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery (Pediatrics 2) 102・2

      Pages: 197-206

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] γ-catenin expression correlates with good prognosis in medulloblastomas.2005
    • Author(s)
      Misaki K, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery : Pediatrics (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Oncogenic β-catenin signaling networks in colorectal cancer2005
    • Author(s)
      Fuchs SY, et al., Minamoto T
    • Journal Title

      Cell Cycle 4・11

      Pages: 1522-1539

    • NAID

      120000812645

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Oncogenic β-catenin signaling networks in colorectal cancer.2005
    • Author(s)
      Fuchs SY, Ougolkov AV, Spiegelman VS, Minamoto T.
    • Journal Title

      Cell Cycle 4(11)

      Pages: 1520-1537

    • NAID

      120000812645

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population2005
    • Author(s)
      Aoki M, Minamoto T, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 335・2

      Pages: 566-574

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Adhesiveness of β5 integrin variant lacking FNK^<767-769> is similar to that of the prototype containing_FNKFNK^<767-769>.2005
    • Author(s)
      Kawahara E, Saito A, Kobayashi J, Maenaka S, Minamoto T, Akasofu-Imai M, Oda Y.
    • Journal Title

      Cell Biol Int 29(7)

      Pages: 521-528

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] A full genome scan for gastric cancer.2005
    • Author(s)
      Aoki M, Yamamura Y, Noshiro H, Sakai K, Yokota J, Kohno T, Tokino T, Ishida S, Ohyama S, Ninomiya I, Uesaka K, Kitajima M, Shimada S, Matsuno S, Yano M, Hiratsuka M, Sugimura H, Itoh F, Minamoto T, Maehara Y, Takenoshita S, Aikou T, Katai H, Yoshimura K, Takahashi T, Akagi K, Sairenji M, Yamamoto K, Sasazuki T.
    • Journal Title

      J Med Genet 42(1)

      Pages: 83-87

    • NAID

      120001130409

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Correlation of γ-catenin expression with good prognosis in medulloblastomas2005
    • Author(s)
      Misaki K, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery (Pediatrics 2) 102・2

      Pages: 197-206

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] A full genome scan for gastric cancer2005
    • Author(s)
      Aoki M, Minamoto T, et al.
    • Journal Title

      Journal of Medical Genetics 42・1

      Pages: 83-87

    • NAID

      120001130409

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Adhesiveness of β5 integrin variant lacking FNK^<767-769> is similar to that of the prototype containing FNKFNK^<767-769>2005
    • Author(s)
      Kawahara E, Minamoto T, et al.
    • Journal Title

      Cell Biology International 29・7

      Pages: 521-528

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Oneogenic β-catenin signaling networks in colorectal cancer2005
    • Author(s)
      Fuchs SY, et al., Minamoto T.
    • Journal Title

      Cell Cycle 4・11

      Pages: 1522-1539

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Deregulated GSK3beta activity in colorectal cancer : Its association with tumor cell survival and proliferation.2005
    • Author(s)
      Shakoori A, Ougolkov A, Yu XW, Zhang B, Modarresi MH, Biladeau DD, Mai M, Takahashi Y, Minamoto T.
    • Journal Title

      Biochem Bioph Res Co 334

      Pages: 1365-1373

    • Data Source
      KAKENHI-PROJECT-17591382

  • [Journal Article] Deregulated GSK3β activity in colorectal cancer : its association with tumor cell survival and proliferation2005
    • Author(s)
      Shakoori A, et al., Takahashi Y, Minamoto T
    • Journal Title

      Biochemical and Biophysical Research Communications 334・4

      Pages: 1365-1373

    • NAID

      120000812884

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] A full genome scan for gastric cancer.2005
    • Author(s)
      Aoki M, Minamoto T, et al.
    • Journal Title

      Journal of Medical Genetics 42・1

      Pages: 83-87

    • NAID

      120001130409

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] γ-catenin expression correlates with good prognosis in medulloblastomas.2005
    • Author(s)
      Misaki K, Minamoto T, et al.
    • Journal Title

      Journal of Neurosurgery : Pediatrics (印刷中)

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Oncogenic β-catenin signaling networks in colorectal cancer2005
    • Author(s)
      Fuchs SY, et al., Minamoto T
    • Journal Title

      Cell Cycle 4・11

      Pages: 1522-1539

    • NAID

      120000812645

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Associations among β-TrCP, an E3 ubiquitin ligase receptor, β-catenin and NF-κB in colorectal cancer.2004
    • Author(s)
      Ougolkov A, Zhang B, Yamashita K, Bilim V, Mai M, Fuchs SY, Minamoto T.
    • Journal Title

      J Natl Cancer Inst 96(15)

      Pages: 1161-1170

    • NAID

      120000812221

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Pilot study of low dose, divided maximum tolerated dose of CPT-11 in 21 consecutive patients with metastatic colorectal or gastric cancer2004
    • Author(s)
      Takahashi Y, Minamoto T, et al.
    • Journal Title

      Surgery Today 34・3

      Pages: 246-250

    • NAID

      10014172519

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Epidermoid cyst of the intrapancreatic accessory spleen producing CA19-9.2004
    • Author(s)
      Watanabe H, Minamoto T, et al.
    • Journal Title

      Digestive Endoscopy 16・3

      Pages: 244-248

    • NAID

      10016171404

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Epidermoid cyst of the intrapancreatic accessory spleen producing CA19-9.2004
    • Author(s)
      Watanabe H, Yamaguchi Y, Ohtsubo K, Mouri H, Motoo Y, Yamashita K, Minamoto T, Gabata T, Sawabu N.
    • Journal Title

      Digest Endosc 16(3)

      Pages: 244-248

    • NAID

      10016171404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Epidermoid cyst of the intrapancreatic accessory spleen producing CA19-9.2004
    • Author(s)
      Watanabe H, Minamoto T, et al.
    • Journal Title

      Digestive Endoscopy 16・3

      Pages: 244-248

    • NAID

      10016171404

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Epidermoid cyst of the intrapancreatic accessory spleen producing CA19-92004
    • Author(s)
      Watanabe H, Minamoto T, et al.
    • Journal Title

      Digestive Endoscopy 16・3

      Pages: 244-248

    • NAID

      10016171404

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Pilot study of low dose, divided maximum tolerated dose of CPT-11 in 21 consecutive patients with metastatic coloretal or gastric cancer.2004
    • Author(s)
      Takahashi Y, Minamoto T, et al.
    • Journal Title

      Surgery Today 34・4

      Pages: 246-250

    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Pilot study of low dose, divided maximum tolerated dose of CPT-11 in 21 consecutive patients with metastatic colorectal or gastric cancer.2004
    • Author(s)
      Takahashi Y, Kitakata H, Yamashita K, Yasumoto K, Omote K, Minamoto T, Mai M.
    • Journal Title

      Surg Today 34(3)

      Pages: 246-250

    • NAID

      10014172519

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Pilot study of low dose, divided maximum tolerated dose of CPT-11 in 21 consecutive patients with metastatic colorectal or gastric cancer.2004
    • Author(s)
      Takahashi Y, Minamoto T, et al.
    • Journal Title

      Surgery Today 34・3

      Pages: 246-250

    • NAID

      10014172519

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Associations among β-TrCP, an E3 ubiquitin ligase receptor, β-catenin and NF-κB in colorectal cancer2004
    • Author(s)
      Ougolkov A, et al., Minamoto T.
    • Journal Title

      Journal of National Cancer Institute 96・15

      Pages: 1161-1170

    • NAID

      120000812221

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Associations among β-TrCP, an E3 ubiquitin ligase receptor, β-catenin and NF-κB in colorectal cancer.2004
    • Author(s)
      Ougolkov A, Takahashi Y, et al. Minamoto T
    • Journal Title

      Journal of the National Cancer Institute 96・15

      Pages: 1161-1170

    • NAID

      120000812221

    • Data Source
      KAKENHI-PROJECT-16659354

  • [Journal Article] Collagenofibrotic glomerulopathy with a widespread expression of type V collagen.2003
    • Author(s)
      Morita H, Hasegawa T, Minamoto T, Oda Y, Inui K, Tayama H, Nakao N, Ideura T, Yoshimura A.
    • Journal Title

      Virchow's Archiv 442(2)

      Pages: 163-168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Virchow's Archive2003
    • Author(s)
      Morita H, Minamoto T, et al.
    • Journal Title

      Collagenofibrotic glomerulopathy with a widespread expression of type V collagen 442・2

      Pages: 163-168

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Visualizing the gastric wall with a 30-MHz ultrasonic miniprobe : ex vivo imaging of normal gastric sites and sites of early gastric cancer.2003
    • Author(s)
      Sabet EA, Okai T, Minamoto T, Mai M, Sawabu N
    • Journal Title

      Abdom Imaging 28(2)

      Pages: 252-256

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Visualizing the gastric wall with a 30-MHz ultrasonic miniprobe : cx vivo imaging of normal gastric sites and sites of early gastric cancer2003
    • Author(s)
      Sabet EA, Minamoto T, et al.
    • Journal Title

      Abdominal Imaging 28・2

      Pages: 252-256

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Endosonographic evaluation of c-kit-positive gastrointestinal stromal tumor.2003
    • Author(s)
      Okai T, Minamoto T, Ohtsubo K, Minato H, Kurumaya H, Oda Y, Mai M, Sawabu N.
    • Journal Title

      Abdom Imaging 28(3)

      Pages: 301-307

    • NAID

      120000811915

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Expression of αv integrin family in gastric carcinomas : increased αvβ6 is associated with lymph node metastasis2003
    • Author(s)
      Kawashima A, Minamoto T, et al.
    • Journal Title

      Pathology Research and Practice 199・2

      Pages: 57-64

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Expression of αv integrin family in gastric carcinomas : increased αvβ6 is associated with lymph node metastasis.2003
    • Author(s)
      Kawashima A, Tsugawa S, Boku A, Kobayashi M, Minamoto T. Nakanishi I, Oda Y.
    • Journal Title

      Pathol Res Prac 199(2)

      Pages: 57-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] β-catenin and ras oncogenes detect most human colorectal cancers.2003
    • Author(s)
      Zhang B, Ougolkov A, Yamashita K, Takahashi Y, Mai M, Minamoto T.
    • Journal Title

      Clin Cancer Res 9(8)

      Pages: 3073-3079

    • NAID

      120000812387

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Abnormal expression of E-eadherin, β-catenin and c-erbB-2 in gastric cancer with liver metastasis2003
    • Author(s)
      Ougolkov A, Takahashi Y, et al., Minamoto T.
    • Journal Title

      International Journal of Colorectal Disease (Clinical and Molecular Gastroenterology and Surgery) 18・2

      Pages: 160-166

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Abnormal expression of E-cadherin, β-catenin and c-erbB-2 in gastric cancer with liver metastasis.2003
    • Author(s)
      Ougolkov A, Yamashita K, Bilim V, Takahashi Y, Mai M, Minamoto T.
    • Journal Title

      Int J Colorect Dis (Clin Mol Gastrocnterol Surg) 18(2)

      Pages: 160-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Endosonographie evaluation of c-kit-positive gastrointestinal stromal tumor2003
    • Author(s)
      Okai T, Minamoto T, et al.
    • Journal Title

      Abdominal Imaging 28・3

      Pages: 301-307

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] β-catenin and ras oncogenes detect most human colorectal cancers2003
    • Author(s)
      Zhang B, Takahashi Y, et al., Minamoto T.
    • Journal Title

      Clinical Cancer Research 9・8

      Pages: 3073-3079

    • NAID

      120000812387

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Journal Article] Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection2000
    • Author(s)
      Maenaka S, Hikichi T, Imai-Akasofu M, Minamoto T, Kawahara E.
    • Journal Title

      Oncol Rep 15(4)

      Pages: 791-795

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Journal Article] Effect of adjuvant immunochemotherapy with Coriolus versicolor mycelium-derived polysccharide K for colon cancer with oncogine beta-catenin activation
    • Author(s)
      Yamashita K, Nakazato H, Ito K, Ougolkov AV, Kitakata H, Yasumoto K, Omote K, Mai M, Takahashi Y, Minamoto T
    • Journal Title

      Diseases of Colon and Rectum (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591382

  • [Journal Article] Effect of adjuvant immunochemotherapy with Coriolus versicolor mycelium-derived polysccharide K for colon cancer with oncogine beta-catenin activation
    • Author(s)
      Yamashita K, Nakazato H, Ito K, Ougolkov AV, Kitakata H, Yasumoto K, Mai M, Takahashi Y, Minamoto T.
    • Journal Title

      Deseases of Colon and Rectum (印刷中)

    • Data Source
      KAKENHI-PROJECT-17591382

  • [Patent] 膵臓癌治療剤2013
    • Inventor(s)
      島崎猛夫、中田光俊、源利成
    • Industrial Property Rights Holder
      学校法人金沢医科大学、国立大学法人金沢大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-093072
    • Filing Date
      2013-04-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Patent] 膵臓癌治療剤2013
    • Inventor(s)
      島崎猛夫、中田光俊、源利成
    • Industrial Property Rights Holder
      金沢医科大学、金沢大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-093072
    • Filing Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Patent] 膵臓癌治療剤2013
    • Inventor(s)
      島崎猛夫、中田光俊、源利成
    • Industrial Property Rights Holder
      島崎猛夫、中田光俊、源利成
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Patent] 脳腫瘍治療用キット及び脳腫瘍治療方法2010
    • Inventor(s)
      中田光俊, 源利成, 林裕, 渡田潤一郎
    • Industrial Property Rights Holder
      国立大学法人金沢大学
    • Industrial Property Number
      2010-185691
    • Filing Date
      2010-08-22
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Patent] 脳腫瘍治療用キット及び脳腫瘍治療方法2010
    • Inventor(s)
      中田光俊,源 利成,ほか
    • Industrial Property Rights Holder
      国立大学法人金沢大学
    • Industrial Property Number
      2010-185691
    • Filing Date
      2010-08-22
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Patent] 癌患者の外科的手術後の治療選択方法及び予後診断2008
    • Inventor(s)
      川上和之, 源利成
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2008-264695
    • Filing Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Patent] 癌患者の外科的手術後の治療選択方法及び予後診断2008
    • Inventor(s)
      川上和之,源利成
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2008-264695
    • Filing Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Patent] 癌患者の外科的手術後の治療選択方法及び予後診断2008
    • Inventor(s)
      川上和之, 源利成
    • Industrial Property Rights Holder
      同左
    • Industrial Property Number
      2008-264695
    • Filing Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Patent] 癌患者の外科的手術後の治療選択方法及び予後診断2008
    • Inventor(s)
      川上和之, 源利成
    • Industrial Property Number
      2008-264695
    • Filing Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] Suppression of cancer and method for evaluating anticancer agent based on the effect of inhibiting GSK3β2007
    • Inventor(s)
      源 利成
    • Filing Date
      2007-07-05
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] 多型部位の遺伝子配列及びヘテロ接合性の消失の判定方法、並びにそれに基づいた癌に対する医薬2007
    • Inventor(s)
      川上和之, 渡邊 剛, 源 利成
    • Industrial Property Number
      2007-019068
    • Filing Date
      2007-01-30
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] GSK3βの阻害効果に基づくがんの抑制および抗がん剤の評価方法2007
    • Inventor(s)
      源 利成
    • Industrial Property Number
      2006-550915
    • Filing Date
      2007-06-21
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] 多型部位の遺伝子配列及びヘテロ接合性の消失の判定方法,並びにそれに基づいた癌に対する医薬2007
    • Inventor(s)
      川上和之, 渡邊剛, 源利成
    • Industrial Property Number
      2007-019068
    • Filing Date
      2007-01-30
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] Suppression of cancer and method for evaluating anticancer agent based on the effect of inhibiting GSK3β2007
    • Inventor(s)
      源 利成
    • Filing Date
      2007-07-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] Suppression of cancer and method for evaluating anticancer agent based on the effect of inhibiting GSK3β2007
    • Inventor(s)
      源利成
    • Filing Date
      2007-07-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] GSK3β 阻害効果に基づくがんの抑制および抗がん剤の評価方法2007
    • Inventor(s)
      源利成
    • Industrial Property Number
      2006-550915
    • Filing Date
      2007-06-21
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] Suppression of cancer and method for evaluating anticancer agent based on the effect of inhibiting GSK3β2007
    • Inventor(s)
      源 利成
    • Filing Date
      2007-07-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Patent] GSK3β阻害効果に基づくがんの抑制および抗がん剤の評価方法2006
    • Inventor(s)
      源 利成
    • Industrial Property Rights Holder
      国立大学法人金沢大学
    • Filing Date
      2006-01-04
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Patent] GSK3β阻害効果に基づくがんの抑制および抗がん剤の評価方法2006
    • Inventor(s)
      源 利成
    • Industrial Property Rights Holder
      国立大学法人金沢大学
    • Filing Date
      2006-01-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390391

  • [Patent] GSK3β阻害効果に基づくがんの抑制および抗がん剤の評価方法2006
    • Inventor(s)
      源 利成
    • Industrial Property Rights Holder
      国立大学法人金沢大学
    • Filing Date
      2006-01-04
    • Data Source
      KAKENHI-PROJECT-16659354

  • [Patent] GSK3β阻害効果に基づく抗がん剤の評価方法2005
    • Inventor(s)
      源 利成
    • Industrial Property Number
      2005-000133
    • Filing Date
      2005-01-04
    • Data Source
      KAKENHI-PROJECT-16659354

  • [Presentation] 食道扁平上皮がんのGSK3β阻害は細胞周期停止とアポトーシスを誘導する．2019
    • Author(s)
      ディリラバ ボリドン，堂本貴寛，上原将大，奥村智之，遠藤良夫，イリア ピコ，宮下知治，中田光俊，源 利成．
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 非乳頭十二指腸腫瘍におけるDNAメチル化解析．2019
    • Author(s)
      澤田　武, 太田亮介, 鈴木　拓, 津山 翔, 八尾隆史, 中西宏佳, 山本英一郎, 久保田英嗣, 片岡洋望, 佐々木泰史, 源　利成．
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 膵がん細胞の薬剤耐性化に伴うがん悪性形質とGSK3βの病理作用．2019
    • Author(s)
      堂本貴寛, 竹中 哲, 宮下知治, 上原将大, 竹内 修, 太田哲生, 源 利成.
    • Organizer
      第28回日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 膵がんのゲムシタビン獲得耐性はglycogen synthase kinase (GSK)-3βに依存する．2019
    • Author(s)
      上原将大，堂本貴寛，竹中 哲，ディリラバ　ボリドン，ピコ イリア，島崎猛夫，宮下知治，太田哲生，源 利成．
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 膵癌細胞エクソソームの抗がん剤による動態変化とその生物学的意義．2019
    • Author(s)
      島崎猛夫，山本聡子，林 祐一，松尾洋一，源 利成．
    • Organizer
      第30回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] GSK3βは膵がんの幹細胞性，浸潤能，薬剤耐性獲得にそれぞれ連関する．2019
    • Author(s)
      堂本貴寛，宮下知治，竹中 哲，上原将大，太田哲夫，源 利成．
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] heat shock protein、Fam107BはGSK3βを介して大腸がん細胞の遊走性を抑制する．2019
    • Author(s)
      小泉惠太，堂本貴寛，中尾啓子，源 利成，中島日出夫．
    • Organizer
      第28回日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 膵がん細胞のゲムシタビン耐性化においてGSK3βは幹細胞性と浸潤能を増強する．2019
    • Author(s)
      堂本貴寛, 竹中 哲, 宮下知治, 上原将大, 太田哲生, 源 利成．
    • Organizer
      第28回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 島崎 猛夫，山本聡子，林 祐一，松尾洋一, 源 利成．膵がん細胞の抗がん剤によるエクソソーム動態変化の解析．2019
    • Author(s)
      島崎 猛夫，山本聡子，林 祐一，松尾洋一, 源 利成．
    • Organizer
      第50回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 十二指腸非乳頭部腫瘍における遺伝子メチル化と変異解析．2019
    • Author(s)
      澤田 武, 太田亮介, 鈴木　拓, 津山 翔, 八尾隆史, 中西宏佳, 波佐谷兼慶, 海崎泰治, 吉田尚弘, 辻 重継, 土山寿志, 湊 宏, 山本英一郎, 久保田英嗣, 片岡洋望, 佐々木泰史, 源 利成．
    • Organizer
      第30回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] Methylation analysis of non-ampullary duodenal precancerous lesions.2019
    • Author(s)
      Ryosuke Ota, Takeshi Sawada, Hiromu Suzuki, Sho Tsuyama, Takashi Yao, Eiichiro Yamamoto, Hiroyoshi Nakanishi, Shigetsugu Tsuji, Naohiro Yoshida, Hisashi Doyama, Hiroshi Minato, Kenkei Hasatani, Yasuharu Kaizaki, Eiji Kubota, Hiromi Kataoka, Yasushi Sasaki, Toshinari Minamoto.
    • Organizer
      27th United European Gastroenterology (UEG) Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 抗がん剤ゲムシタビンによる膵がん細胞のエクソソーム分泌及びエクソソーム表面マーカーへの影響．2019
    • Author(s)
      山本聡子，松尾洋一，林　祐一，源 利成，島崎猛夫．
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] Glycogen synthase kinase-3β is a new therapeutic target in soft tissue sarcoma: a basic research.2019
    • Author(s)
      Kensaku Abe, Norio Yamamoto, Takahiro Domoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Yuta Taniguchi, Hirotaka Yonezawa, Yoshihiro Araki, Toshinari Minamoto, Hiroyuki Tsuchiya.
    • Organizer
      American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03727

  • [Presentation] 消化器・難治がんの糖代謝特性と治療：創薬標的GSK3βに着目して2017
    • Author(s)
      源 利成
    • Organizer
      第４回山梨医学フォーラム
    • Place of Presentation
      山梨大学医学部，山梨県中央市
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 大腸がんWnt経路研究から同定した治療標的GSK3β：難治，希少がんへの展開2017
    • Author(s)
      源 利成
    • Organizer
      埼玉大腸がん地域連携キャンサーボード
    • Place of Presentation
      ラ・ボア・ラクテ，川越
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] Putative role of glycogen synthase kinase (GSK)-3β in acquired resistance to gemcitabine (GEM) in pancreatic cancer.2017
    • Author(s)
      Masahiro Uehara, Takahiro Domoto, Satoshi Takenaka, Ilya Pyko, Takeo Shimasaki, Tomoharu Miyashita, Tetsuo Ohta, Toshinari Minamoto.
    • Organizer
      The 9th International Conference on the International Society of Gastroenterological Carcinogenesis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 抗がん剤による膵癌細胞のエクソソーム動態への影響2017
    • Author(s)
      島崎猛夫、山本聡子、堂本貴寛、清川悦子、有沢富康、源利成
    • Organizer
      第76回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Presentation] 膵がんのゲムシタビン耐性獲得におけるglycogen synthase kinase (GSK)-3βの役割り．2017
    • Author(s)
      上原将大，堂本貴寛，竹中 哲，ピコ イリア，島崎猛夫，宮下知治，太田哲生，源 利成．
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 消化器・難治がんの糖代謝特性と治療：創薬標的GSK3βに着目して2017
    • Author(s)
      源 利成
    • Organizer
      第４回山梨医学フォーラム
    • Place of Presentation
      山梨大学医学部，山梨県中央市
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 大腸がんWnt経路研究から同定した治療標的GSK3β：難治，希少がんへの展開2017
    • Author(s)
      源 利成
    • Organizer
      埼玉大腸がん地域連携キャンサーボード
    • Place of Presentation
      ラ・ボア・ラクテ，川越
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] Therapeutic effect of glycogen synthase kinase-3β inhibition against osteosarcoma via activation of β-catenin.2017
    • Author(s)
      Shingo Shimozaki, Norio Yamamoto, Takahiro Domoto, Toshinari Minamoto, Robert M. Hoffman, Hiroyuki Tsuchiya.
    • Organizer
      The 19th International Society of Limb Salvage General Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 大腸がん研究から同定した治療標的：難治，希少がんへの展開．2017
    • Author(s)
      源 利成
    • Organizer
      埼玉大腸がん地域連携キャンサーボード
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] ゲムシタビン獲得耐性膵がん細胞の幹細胞性と浸潤能におけるGSK3βの作用．2017
    • Author(s)
      堂本貴寛，竹中 哲，宮下知治，上原将大，太田哲生，源 利成．
    • Organizer
      第26回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 消化器・難治がんの糖代謝特性と治療：創薬標的GSK3βに着目して．2017
    • Author(s)
      源 利成
    • Organizer
      第４回山梨医学フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 抗がん剤による膵がん細胞のエクソソーム動態への影響2017
    • Author(s)
      島崎猛夫、山本聡子、堂本貴寛、源利成
    • Organizer
      第27回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Presentation] Aberrant glycogen synthase kinase (GSK)3β participates in tumor-promoting autophagy in colorectal cancer.2017
    • Author(s)
      Takahiro Domoto, Ilya V. Pyko, Masahiro Uehara, Dilireba Bolidong, Toshinari Minamoto.
    • Organizer
      The 9th International Conference on the International Society of Gastroenterological Carcinogenesis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3βはゲムシタビン獲得耐性膵がんの浸潤を促進する．2017
    • Author(s)
      堂本貴寛，宮下知治，竹中 哲，上原将大，太田哲生，源 利成．
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] Glycogen synthase kinase (GSK)3βの食道扁平上皮がん促進作用の検討．2017
    • Author(s)
      ボリドン ディリレバ，堂本貴寛，奥村知之，遠藤良夫，上原将大，ピコ イリア，宮下知治，源 利成．
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 膵癌細胞のエクソソーム動態の解析2017
    • Author(s)
      島崎猛夫、山本聡子、堂本貴寛、源利成
    • Organizer
      第48回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Presentation] 膵がん治療耐性に伴う幹細胞性とGSK3β/STAT3経路の機能解析．2017
    • Author(s)
      竹中 哲，宮下知治，上原将大，堂本貴寛，源　利成，太田哲生．
    • Organizer
      第26回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 膵癌細胞のエクソソーム動態に影響する因子の検討．2016
    • Author(s)
      島崎猛夫，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] Sensitizing patient-derived glioblastoma stem-like cells to temozolomide by glycogen synthase kinase 3β inhibition.2016
    • Author(s)
      Pyko IV, et al., Minamoto T.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 膵癌細胞のエクソソーム動態に影響する因子の検討．2016
    • Author(s)
      島崎猛夫，ほか，源 利成
    • Organizer
      第27回日本消化器癌発生学会総会
    • Place of Presentation
      城山観光ホテル，鹿児島
    • Year and Date
      2016-09-15
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 膵がんの化学療法耐性獲得にけるglycogen synthase kinase (GSK)-3βの役割．2016
    • Author(s)
      上原将大，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3βはがん促進性オートファジーを介して大腸がん細胞の生存に関与する．2016
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3βを阻害することによる膵臓がんの化学療法耐性解除への可能性．2016
    • Author(s)
      竹中 哲，ほか，源 利成
    • Organizer
      第25回日本がん転移学会学術集会・総会
    • Place of Presentation
      米子コンベンションセンター，米子
    • Year and Date
      2016-07-21
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3β阻害による軟部肉腫の治療効果の検討．2016
    • Author(s)
      阿部健作，源 利成，ほか．
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡国際会議場，福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3βはがん促進性オートファジーを介して大腸がん細胞の生存に関与する．2016
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] Down modulation of glycogen synthase kinase (GSK)-3β disrupts Translocated Promoter Region (Tpr)-dynein axis during mitosis in colon cancer cells.2016
    • Author(s)
      Dewi FRP, Minamoto T, et al.
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都テルサ，京都
    • Year and Date
      2016-06-15
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 膵がんの化学療法耐性獲得にけるglycogen synthase kinase (GSK)-3βの役割．2016
    • Author(s)
      上原将大，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] TJ-14による食道発癌抑制とその機序．2016
    • Author(s)
      宮下知治，源 利成，ほか
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 膠芽腫に対するテモゾロミド併用GSK3β標的療法．2016
    • Author(s)
      古田拓也，源 利成，ほか．
    • Organizer
      第34回日本脳腫瘍学会学術集会
    • Place of Presentation
      甲府富士屋ホテル，甲府
    • Year and Date
      2016-12-04
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] Down modulation of glycogen synthase kinase (GSK)-3β disrupts Translocated Promoter Region (Tpr)-dynein axis during mitosis in colon cancer cells.2016
    • Author(s)
      Dewi FRP, Minamoto T, et al.
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都テルサ，京都
    • Year and Date
      2016-06-15
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3βを阻害することによる膵臓がんの化学療法耐性解除への可能性．2016
    • Author(s)
      竹中 哲，ほか，源 利成
    • Organizer
      25回日本がん転移学会学術集会・総会
    • Place of Presentation
      米子コンベンションセンター，米子
    • Year and Date
      2016-07-21
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] Sensitizing patient-derived glioblastoma stem-like cells to temozolomide by glycogen synthase kinase 3β inhibition.2016
    • Author(s)
      Pyko IV, et al., Minamoto T.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 膵癌細胞のエクソソーム動態に影響する因子の検討．2016
    • Author(s)
      島崎猛夫，ほか，源 利成
    • Organizer
      第27回日本消化器癌発生学会総会
    • Place of Presentation
      城山観光ホテル，鹿児島
    • Year and Date
      2016-09-15
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3β阻害による軟部肉腫の治療効果の検討．2016
    • Author(s)
      阿部健作，源 利成，ほか
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡国際会議場，福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 膵癌細胞のエクソソーム動態に影響する因子の検討．2016
    • Author(s)
      島崎猛夫，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 膠芽腫に対するテモゾロミド併用GSK3β標的療法．2016
    • Author(s)
      古田拓也，源 利成，ほか
    • Organizer
      第34回日本脳腫瘍学会学術集会
    • Place of Presentation
      甲府富士屋ホテル，甲府
    • Year and Date
      2016-12-04
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] TJ-14による食道発癌抑制とその機序．2016
    • Author(s)
      宮下知治，ほか，源 利成
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 抗癌剤により膵癌細胞に誘導されるEMT促進因子の同定と機能解析：GSK3β阻害による制御2015
    • Author(s)
      島崎猛夫，源 利成，ほか
    • Organizer
      第46回日本膵臓学会大会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-06-19
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3β阻害薬を用いた骨肉腫への分子標的治療2015
    • Author(s)
      下崎真吾，源 利成，ほか
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      国立京都国際会館，京都
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 大腸がん糖代謝特性におけるGSK3βの役割2015
    • Author(s)
      堂本 貴寛, 紙 健次郎, 廣瀬 まゆみ, Ilya V. Pyko, 土原 一哉, 曽我 朋義, 江角 浩安, 源 利成
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      金沢市・県立音楽堂
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PROJECT-25860233

  • [Presentation] ゲムシタビンにより膵癌細胞に誘導されるEMT促進因子の同定と機能解析：GSK3β阻害による制御2015
    • Author(s)
      島崎猛夫，ほか，源 利成
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3βはFAK/Rac1/ JNK経路を介するMMPsの発現亢進によって膠芽腫細胞の浸潤を推進する2015
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3β sustains invasion of glioblastoma by expression of MMPs via the FAK, Rac1 and JNK-mediated pathway2015
    • Author(s)
      Takahiro Domoto, Takuya Furuta, Takahisa Takino, Hiroshi Sato, Mitsutoshi Nakada, Toshinari Minamoto
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋市・名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25860233

  • [Presentation] 抗がん剤により膵がん細胞に誘導される分子とエクソソームを介した細胞間相互作用の解析2015
    • Author(s)
      島崎猛夫，山本聡子，源 利成
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子全日空ホテル，米子
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] Biological basis of cancer treatment by GSK3β inhibition2015
    • Author(s)
      Minamoto T
    • Organizer
      International Symposium on Tumor Biology in Kanazawa
    • Place of Presentation
      金沢大学十全記念館，金沢
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] エクソソームを介する癌細胞間相互作用：新しい培養プレートによる解析2015
    • Author(s)
      山本聡子，源 利成，ほか
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 大腸がん糖代謝特性におけるGSK3βの役割2015
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      石川県立音楽堂，金沢
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] ゲムシタビンにより膵癌細胞に誘導されるEMT促進因子の同定と機能解析：GSK3β阻害による制御2015
    • Author(s)
      島崎猛夫，ほか，源 利成
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3βはFAK-Rac1-JNK経路を介して膠芽腫細胞の浸潤を推進する2015
    • Author(s)
      堂本 貴寛, 滝野 隆久, 佐藤 博, 源 利成
    • Organizer
      第24回日本がん転移学会学術集会・総会
    • Place of Presentation
      大阪市・シティプラザ大阪
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-25860233

  • [Presentation] 既存薬転用を応用した膠芽腫に対するGSK3β標的治療2015
    • Author(s)
      古田拓也，ほか，源 利成
    • Organizer
      第16回日本分子脳神経外科学会
    • Place of Presentation
      アクトシティ浜松コングレスセンター，浜松
    • Year and Date
      2015-08-28
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 抗がん剤により膵がん細胞に誘導される分子とエクソソームを介した細胞間相互作用の解析2015
    • Author(s)
      島崎 猛夫、山本聡子、源 利成
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子全日空ホテル（鳥取県米子市）
    • Year and Date
      2015-11-09
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Presentation] 大腸がん糖代謝特性におけるGSK3βの役割2015
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      石川県立音楽堂，金沢
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] GSK3βはFAK-Rac1-JNK経路を介して膠芽腫細胞の浸潤を推進する2015
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第24回日本がん転移学会学術集会・総会
    • Place of Presentation
      シティプラザ大阪，大阪
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] エクソソームを介する癌細胞間相互作用：新しい培養プレートによる解析2015
    • Author(s)
      山本聡子，源 利成，ほか
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3β阻害薬を用いた骨肉腫への分子標的治療2015
    • Author(s)
      下崎真吾，源 利成，ほか
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      京都国際会議場，京都
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 既存薬転用を応用した膠芽腫に対するGSK3β標的治療2015
    • Author(s)
      古田拓也，源 利成，ほか
    • Organizer
      第16回日本分子脳神経外科学会
    • Place of Presentation
      アクトシティ浜松コングレスセンター，浜松
    • Year and Date
      2015-08-28
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] iological basis of cancer treatment by GSK3β inhibition2015
    • Author(s)
      Minamoto T
    • Organizer
      International Symposium on Tumor Biology in Kanazawa
    • Place of Presentation
      金沢大学十全記念館，金沢
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 抗癌剤により膵癌細胞に誘導されるＥＭＴ促進因子の同定と機能解析：ＧＳＫ３β阻害による制御2015
    • Author(s)
      島崎猛夫、元雄良治、源 利成、友杉直久
    • Organizer
      第46回日本膵臓学会大会
    • Place of Presentation
      名古屋国際会議場（愛知県名古屋市）
    • Year and Date
      2015-06-19
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Presentation] Identification and analysis of EMT-inducible factor by gemcitabine in pancreatic cancer cells2015
    • Author(s)
      Takeo Shimasaki, Satoko Yamamoto, Takahiro Domoto, Tomiyasu Arisawa, Naohisa Tomosugi, Toshinari Minamoto
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋市・名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25860233

  • [Presentation] GSK3βはFAK/Rac1/ JNK経路を介するMMPsの発現亢進によって膠芽腫細胞の浸潤を推進する2015
    • Author(s)
      堂本貴寛，ほか，源 利成
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04928

  • [Presentation] 抗がん剤により膵がん細胞に誘導される分子とエクソソームを介した細胞間相互作用の解析2015
    • Author(s)
      島崎猛夫，山本聡子，源 利成
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子全日空ホテル，米子
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] 抗癌剤により膵癌細胞に誘導されるEMT促進因子の同定と機能解析：GSK3β阻害による制御2015
    • Author(s)
      島崎猛夫，源 利成，ほか
    • Organizer
      第46回日本膵臓学会大会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Year and Date
      2015-06-19
    • Data Source
      KAKENHI-PROJECT-15K15493

  • [Presentation] GSK3β阻害によるβ-カテニン活性化の骨肉腫治療効果2015
    • Author(s)
      下﨑真吾, 山本憲男, 林 克洋, 木村浩明, 武内章彦, 三輪真嗣, 稲谷弘幸, 青木 裕, 樋口貴史, 阿部健作, 堂本貴寛, 大塚隆信, 源 利成, 土屋弘行
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      京都市・国立京都国際会館
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-25860233

  • [Presentation] ゲムシタビンにより膵癌細胞に誘導されるEMT促進因子の同定と機能解析：ＧＳＫ　３β阻害による制御2015
    • Author(s)
      島崎猛夫、山本聡子、源 利成
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K09051

  • [Presentation] Phase I clinical trial of the combination therapy using gemcitabine and GSK3beta inhibiting drugs for gemcitabine-resistant advanced pancreatic cancer patients2014
    • Author(s)
      Shimasaki T, Tomosugi N, Minamoto T, et al.
    • Organizer
      DDW 2014
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Presentation] Therapeutic effect of the cocktail of GSK3β-inhibiting drugs against colon cancer2014
    • Author(s)
      Mayumi Hirose, Takahiro Domoto, Toshinari Minamoto
    • Organizer
      金沢国際がん生物学シンポジウム＆アカデミア創薬シンポジウム
    • Place of Presentation
      金沢・エクセル東急
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Therapeutic effect of the cocktail of GSK3beta-inhibiting drugs against colon cancer2014
    • Author(s)
      Mayumi Hirose, Takahiro Domoto, Toshinari Minamoto
    • Organizer
      金沢国際がん生物学シンポジウム&アカデミア創薬シンポジウム
    • Place of Presentation
      金沢・エクセル東急
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] GSK3β in cancer cell metabolism.2014
    • Author(s)
      Toshinari Minamoto
    • Organizer
      International Symposium on Tumor Biology in Kanazawa 2014 & Symposium on Drug Discovery in Academics
    • Place of Presentation
      金沢エクセルホテル東急，金沢
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] Inhibition of GSK3β rectifies aberrant glucose metabolism in colon cancer cells.2014
    • Author(s)
      Takahairo Domoto, et al, Toshinari Minamoto
    • Organizer
      International Symposium on Tumor Biology in Kanazawa 2014 & Symposium on Drug Discovery in Academics
    • Place of Presentation
      金沢エクセルホテル東急，金沢
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] Therapeutic effect of the cocktail of GSK3β-inhibiting drugs against colon cancer.2014
    • Author(s)
      Mayumi Hirose, et al, Toshinari Minamoto
    • Organizer
      International Symposium on Tumor Biology in Kanazawa 2014 & Symposium on Drug Discovery in Academics
    • Place of Presentation
      金沢エクセルホテル東急，金沢
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 大腸がんの糖代謝経路におけるGSK3betaの機能解析2013
    • Author(s)
      堂本貴寛、廣瀬まゆみ、紙健次郎、曽我朋義、江角浩安、源利成
    • Organizer
      第24回日本消化器癌発生学会総会
    • Place of Presentation
      金沢・石川県立音楽堂
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] GSK3β阻害作用を有する既存薬剤を用いた再発膠芽腫の免疫組織学的検討．2013
    • Author(s)
      宮下勝吉，源　利成，ほか．
    • Organizer
      第31回日本脳腫瘍病理学会
    • Place of Presentation
      FKC Hall国際ファッションセンター，東京
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 既存医薬品を用いたGSK3β阻害による大腸がん治療法の開発．2013
    • Author(s)
      廣瀬まゆみ，ほか，源 利成．
    • Organizer
      第24回日本消化器癌発生学会総会
    • Place of Presentation
      石川県立音楽堂，金沢
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] SK3betaを標的とした既存医薬品を用いた大腸がん治療の開発2013
    • Author(s)
      廣瀬まゆみ、堂本貴寛、伊藤有美、川上和之、源利成
    • Organizer
      第78回大腸癌研究会
    • Place of Presentation
      東京・都市センターホテル
    • Year and Date
      2013-01-18
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 大腸がんの糖代謝経路におけるGSK3βの機能解析．2013
    • Author(s)
      堂本貴寛，ほか，源　利成．
    • Organizer
      第24回日本消化器癌発生学会総会
    • Place of Presentation
      石川県立音楽堂，金沢
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 大腸癌における核膜孔複合体因子とβ-cateninの相互作用と機能解析．2013
    • Author(s)
      藻寄 茜，源　利成，ほか．
    • Organizer
      第24回日本消化器癌発生学会総会
    • Place of Presentation
      石川県立音楽堂，金沢
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 多機能キナーゼGSK3βを標的とした膠芽腫治療の基礎と臨床．2013
    • Author(s)
      中田光俊，源　利成，ほか．
    • Organizer
      第72回日本脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 大腸がんの糖代謝経路におけるGSKβの機能解析2013
    • Author(s)
      堂本貴寛、廣瀬まゆみ、紙健次郎、曽我朋義、江角浩安、源利成
    • Organizer
      第２４回日本消化器癌発生学会総会
    • Place of Presentation
      金沢・石川県立音楽堂
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 既存医薬品を用いたGSK3beta阻害による大腸がん治療法の開発2013
    • Author(s)
      廣瀬まゆみ、堂本貴寛、伊藤友美、源利成
    • Organizer
      第24回日本消化器癌発生学会総会
    • Place of Presentation
      金沢・石川県立音楽堂
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] GSK3βを標的とする骨肉腫の新規治療法の可能性．2013
    • Author(s)
      下﨑真吾，源　利成，ほか．
    • Organizer
      第51回日本癌治療学会学術集会
    • Place of Presentation
      国立京都国際会館，京都
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 多機能キナーゼGSK3βを標的とした膠芽腫治療の基礎と臨床2013
    • Author(s)
      中田光俊、林裕,古田拓也、宮下勝吉、淑瑠ヘムラサビット、ピコイリア、田中慎吾、喜多大輔、毛利正直、林康彦、内山尚之、源利成、濵田潤一郎
    • Organizer
      第72回日本脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] 多機能キナーゼGSK3βを標的とした膠芽腫治療の基礎と臨床2013
    • Author(s)
      中田光俊、林裕，古田拓也、宮下勝吉、淑瑠ヘムラサビット、ピコイリア、田中慎吾、喜多大輔、毛利正直、林康彦、内山尚之、源利成、濵田潤一郎
    • Organizer
      第72回日本脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜（神奈川県）
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] 既存医薬品を用いたGSKβ阻害による大腸がん治療法の開発2013
    • Author(s)
      廣瀬まゆみ、堂本貴寛、源利成
    • Organizer
      第２４回日本消化器癌発生学会総会
    • Place of Presentation
      金沢・石川県立音楽堂
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 膠芽腫マウスモデルに対する既存のGSK3β阻害医薬品の効果．2013
    • Author(s)
      古田拓也，源　利成，ほか．
    • Organizer
      第72回日本脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] 大腸がん細胞の糖代謝特性におけるGSK3β の病的作用2013
    • Author(s)
      堂本貴寛、廣瀬まゆみ、曽我朋義、江角浩安、源利成
    • Organizer
      第７２回日本癌学界学術総会
    • Place of Presentation
      横浜・パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 膠芽腫細胞株に対するGSK3β阻害医薬品の効果解析．2013
    • Author(s)
      古田拓也，源　利成，ほか．
    • Organizer
      第31回日本脳腫瘍学会
    • Place of Presentation
      フェニックス・シーガイアリゾート，宮崎
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3β阻害作用を有する既存薬剤を用いた再発膠芽腫治療の第I・II相臨床試験における患者背景とバイオマーカーに関する検討．2013
    • Author(s)
      宮下勝吉，源　利成，ほか．
    • Organizer
      第72回日本脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3β阻害による膠芽腫のテモゾロミド増感作用とc-mycシグナルを介したMGMTプロモーターメチル化促進効果．2013
    • Author(s)
      中田光俊，源　利成，ほか．
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] Targeting GSK3β in colorectal and refractory cancers.2013
    • Author(s)
      Toshinari Minamoto.
    • Organizer
      7th Conference of the International Society of Gastroenterological Carcinogenesis
    • Place of Presentation
      University of Pennsylvania, Philadelphia, PA, U.S.A.
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] DNAメチル化パターンからみた大腸がんの特徴．2013
    • Author(s)
      小竹優範，ほか，源　利成．
    • Organizer
      第24回日本消化器癌発生学会総会
    • Place of Presentation
      石川県立音楽堂，金沢
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3β is an emerging therapeutic target in pancreatic cancer: its implication for cancer cell migration and invasion.2013
    • Author(s)
      Takeo Shimasaki, Toshinari Minamoto, et al.
    • Organizer
      DDW 2013
    • Place of Presentation
      Orange County Convention Center, Orlando, FL, U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3βを標的治療とした既存医薬品による膵がんの新規治療．2013
    • Author(s)
      島崎猛夫，源　利成，ほか．
    • Organizer
      第44回日本膵臓学会大会
    • Place of Presentation
      仙台国際センター，仙台
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3βis an emerging therapeutic target in pancreatic cancer : its implication for cancer cell migration and invasion2013
    • Author(s)
      Shimasaki T, Ishigaki Y, Tomosugi N, Minamoto T, et al.
    • Organizer
      DDW 2013
    • Place of Presentation
      Orland, FL, USA
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Presentation] 大腸がん細胞の糖代謝特性におけるGSK3βの病的作用．2013
    • Author(s)
      堂本貴寛，ほか，源　利成．
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3βinhibition sensitizes glioblastoma cells to temozolomide by MGMT promoter methylation via c-Myc signaling2013
    • Author(s)
      中田光俊、ピコイリア、淑瑠ヘムラサビット、林裕、源利成、濵田潤一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] GSK3βを標的治療とした既存医薬品による膵がんの新規治療2013
    • Author(s)
      島崎猛夫,石垣靖人,源利成,友杉直久他
    • Organizer
      第44回日本膵臓学会大会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Presentation] GSK3β阻害作用を有する医薬品の大腸がんに対する治療効果2013
    • Author(s)
      廣瀬まゆみ、堂本貴寛、源利成
    • Organizer
      第７２回日本癌学界学術総会
    • Place of Presentation
      横浜・パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 再発膠芽腫にGSK3β阻害作用を有する薬剤を用いた第I・II相臨床試験．2013
    • Author(s)
      宮下勝吉，源　利成，ほか．
    • Organizer
      第31回日本脳腫瘍学会
    • Place of Presentation
      フェニックス・シーガイアリゾート，宮崎
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] がんの代謝と治療標的GSK3βの接点2013
    • Author(s)
      源　利成
    • Organizer
      日本癌学会がんと代謝シンポジウム2013
    • Place of Presentation
      慶應義塾大学北里記念医学図書館講堂（東京都）
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Glycogen synthase kinase 3β promotes glioma invasion via FAK/Rac1/JNK/MMP pathway.2013
    • Author(s)
      Mitsutoshi Nakada, Toshinari Minamoto, et al.
    • Organizer
      4th Quadrennial Meeting of the World Federation of Neuro-Oncology & 18th Annual Meeting of the Society for Neuro-Oncology
    • Place of Presentation
      Marriott Marquis Hotel, San Francisco, California, U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3β inhibition sensitizes glioblastoma cells to temozolomide by MGMT promoter methylation via c-Myc signaling2013
    • Author(s)
      中田光俊、ピコイリア、淑瑠ヘムラサビット、林裕、源利成、濵田潤一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県）
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] Glycogen synthase kinase 3βpromotes glioma invasion via the FAK/Rac1/JNK/MMP2 pathway2013
    • Author(s)
      Nakada M, Furuta T, Sabit H, Chikano Y, Hayashi Y, Sato H, Minamoto T, Hamada JI
    • Organizer
      4^<rd> Quadrennial Meeting of the World Federation of Neuro-Oncology
    • Place of Presentation
      Marriott Marquis Hotel, San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] GSK3β阻害作用を有する医薬品の大腸がんに対する治療効果．2013
    • Author(s)
      廣瀬まゆみ，ほか，源 利成．
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] GSK3βを標的とした既存医薬品を用いた大腸がん治療の開発2013
    • Author(s)
      廣瀬まゆみ、堂本貴寛、伊藤有美、川上和之、源利成
    • Organizer
      第 78 回大腸癌研究会
    • Place of Presentation
      東京都（都市センターホテル）
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 骨肉腫に対するGSK-3β阻害薬を用いた分子標的治療．2013
    • Author(s)
      下﨑真吾，源　利成，ほか．
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      幕張メッセ国際会議場，幕張，千葉
    • Data Source
      KAKENHI-PROJECT-25670572

  • [Presentation] Therapeutic effect of GSK3β inhibition by drugs in clinical use against colon and pancreatic cancer2013
    • Author(s)
      Mayumi Hirose, Takahiro Domoto, Yumi Ito, Kazuyuki Kawakami, Toshinari Minamoto:
    • Organizer
      第３回発がんスパイラル国際シンポジウム　＆　金沢国際がん生物学シンポジウム
    • Place of Presentation
      石川県（金沢エクセルホテル東急）
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Putative pathological role of GSK3beta in aberrant glucose metabolism in colon cancer cells:大腸がん細胞の糖代謝特性におけるGSK3betaの病的作用2013
    • Author(s)
      Domoto Takahiro1, Mayumi Hirose, Tomoyoshi Soga, Hiroyasu Esumi, Toshinari Minamoto
    • Organizer
      第72回日本癌学界学術総会
    • Place of Presentation
      横浜・パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Glycogen synthase kinase 3β promotes glioma invasion via the FAK/Rac1/JNK/MMP2 pathway.2013
    • Author(s)
      Nakada M, Furuta T, Sabit H, Chikano Y, Hayashi Y, Sato H, Minamoto T, Hamada JI.
    • Organizer
      4rd Quadrennial Meeting of the World Federation of Neuro-Oncology
    • Place of Presentation
      Marriott Marquis Hotel, San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] Therapeutic effect of the GSK3beta-inhibiting drugs against colon cancer:GSK3beta阻害作用を有する医薬品の大腸がんに対する治療効果2013
    • Author(s)
      Mayumi Hirose, Yumi Ito, Takahiro Domoto , Toshinari Minamoto
    • Organizer
      第72回日本癌学界学術総会
    • Place of Presentation
      横浜・パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
    • Author(s)
      Kawakami K, Matsunoki A, Kotake M, Kaneko M, Kitamura H, Watanabe G, Minamoto T
    • Organizer
      22nd Biennial Congress of the European Association for Cancer Research
    • Place of Presentation
      Centre Convencions International Barcelona, Spain
    • Year and Date
      2012-07-08
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase2012
    • Author(s)
      Minamoto T, Mai W, Kyo S, Shakoori A, Miyashita K, Yokoi K, Shimasaki T, Motoo Y, Kawakami K
    • Organizer
      103rdAnnual Meeting of American Association for Cancer Research
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer.2012
    • Author(s)
      Matsunoki A, Kawakami K, Kotake M, KanekoM, Watanabe G, Minamoto T.
    • Organizer
      103rd Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] LINE-1 methylation level is a potential marker of the sensitivity to 5-FU plus oxaliplatin in colorectal cancer cells2012
    • Author(s)
      Kaneko M, Kawakami K, Kotake M, Kitamura H, Watanabe G, Minamoto T
    • Organizer
      71st Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      ホテルロイトン札幌(北海道)
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] Phase I/II study for recurrent glioblastoma with the drugs inhibiting GSK3β2012
    • Author(s)
      Nakada M, Hayashi Y, Miyashita K, Kinoshita M, Furuta T, Sabit H, kita D, Hayashi Y, Uchiyama N, Kawakami K, Minamoto T, Hamada JI
    • Organizer
      Society for Neuro-Onology 17th Annual Meeting 2011
    • Place of Presentation
      Hilton Hotel, Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] 膵癌の新規治療標的としてのglycogen synthase kinase (GSK) 3β:がん浸潤に対する作用2012
    • Author(s)
      島崎猛夫,石垣靖人,源利成,友杉直久他
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Presentation] Aberrant glycogen synthase kinase 3β is involved in glioma invasion2012
    • Author(s)
      Nakada M, Chikano Y, Sabit H, Furuta T, Miyashita K, Hayashi Y, Sato H, Kawakami K, Minamoto T, Hamada JI
    • Organizer
      9th Meeting for the Asian Society for Neuro-Oncology
    • Place of Presentation
      Taipei International Convention Center, Taiwan
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] GSK3β標的治療と化学療法を併用する膵がんの新規治療戦略と分子基盤2012
    • Author(s)
      島崎猛夫,石垣靖人,源利成,友杉直久他
    • Organizer
      第43回日本膵臓学会大会
    • Place of Presentation
      ホテルメトロポリタン山形
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Presentation] Aberrant glycogen synthase kinase 3βis involved in glioma invasion2012
    • Author(s)
      Nakada M, Chikano Y, Sabit H, Furuta T, Miyashita K, Hayashi Y, Sato H, Kawakami K, Minamoto T, Hamada JI
    • Organizer
      9^<th >Meeting for the Asian Society for Neuro-Oncology
    • Place of Presentation
      Taipei International Convention Center, Taiwan
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell.2012
    • Author(s)
      Kawakami K, Matsunoki A, Kotake M, KanekoM, Kitamura H, Watanabe G, Minamoto T.
    • Organizer
      22nd Biennial Congress of the European Association for Cancer Research
    • Place of Presentation
      Centre Convencions International Barcelona, Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] GSK3β阻害作用を有する既存薬剤を用いた再発膠芽腫治療の第I・II相臨床試験2012
    • Author(s)
      中田光俊、林裕、宮下勝吉、木下雅史、古田拓也、淑瑠ヘムラサビット、喜多大輔、林康彦、内山尚之、川上和之、源利成、濵田潤一郎
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜（神奈川県）
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] がんの代謝と治療標的GSK3βの接点2012
    • Author(s)
      堂本貴寛,源 利成
    • Organizer
      日本癌学会シンポジウム:がんと代謝シンポジウム
    • Place of Presentation
      慶應義塾大学医学部信濃町キャンパス北里記念医学図書館講堂,東京
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer.2012
    • Author(s)
      Matsunoki A, Kawakami K, Kotake M, KanekoM, Watanabe G, Minamoto T
    • Organizer
      103rdAnnual Meeting of American Association for Cancer Research
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell.2012
    • Author(s)
      Kawakami K, Matsunoki A, Kotake M, kaneko M, Kitamura H, Watanabe G, Minamoto T
    • Organizer
      22nd Biennial Congress of the European Association for Cancer Research
    • Place of Presentation
      Barcelona, Spain (Center Conventions International Barcelona)
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase2012
    • Author(s)
      Toshinari Minamoto
    • Organizer
      103rd Annual Meeting of American Association for Cancer Research (AACR 2012)
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
    • Author(s)
      Matsunoki A. Kawakami K. Kotake M. Kaneko M. Watanabe G. Minamoto T
    • Organizer
      103th Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Illinois, U.S.A. (McCormick Place)
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] GSK3β阻害作用を有する既存薬剤を用いた再発膠芽腫治療の第I・II相臨床試験2012
    • Author(s)
      中田光俊、林裕、宮下勝吉、木下雅史、古田拓也、淑瑠ヘムラサビット、喜多大輔、林康彦、内山尚之、川上和之、源利成、濵田潤一郎
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-23592117

  • [Presentation] Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase.2012
    • Author(s)
      Minamoto T, Mai W, Kyo S, Shakoori A, Miyashita K, Yokoi K, Shimasaki T, Motoo Y, Kawakami K.
    • Organizer
      103rd Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Knockdown of LINE-1 enhances sensitivity to 5-FU in LINE-1-hypomethylated colorectal cancer cell2012
    • Author(s)
      Kawakami K, Matsunoki A, Kotake M, Kaneko M, Kitamura H, Watanabe G, Minamoto T
    • Organizer
      22ndBiennial Congress of the European Association for Cancer Research
    • Place of Presentation
      Centre Convencions International Barcelona, Barcelona, Spain
    • Year and Date
      2012-07-10
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] GSK3β標的治療を併用した膵癌の新規治療戦略と分子基盤2012
    • Author(s)
      島崎猛夫,石垣靖人,源利成,友杉直久他
    • Organizer
      第20回JDDW
    • Place of Presentation
      神戸国際展示場・ポートピアホテル・神戸こうくさい会議場
    • Data Source
      KAKENHI-PROJECT-23591016

  • [Presentation] LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer2012
    • Author(s)
      Matsunoki A, Kawakami K, Kotake M, Kaneko M, Watanabe G, Minamoto T
    • Organizer
      103rd Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      McCormick Place in Chicago (USA)
    • Year and Date
      2012-04-02
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] Deregulated GSK3β sustains gastrointestinal cancer cells by modulating hTERT and telomerase2012
    • Author(s)
      Minamoto T
    • Organizer
      103rd Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      McCormick Place (USA)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 膵癌に新規治療標的としてのglycogen synthase kinase (GSK) 3β：化学療法戦略の新展開2011
    • Author(s)
      島崎猛夫，川上和之，源 利成，ほか
    • Organizer
      第70回日本癌学会総会学術集会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] 新規熱ショック誘導性蛋白質(HITS)の発現を利用した癌の診断2011
    • Author(s)
      中島日出夫,源利成,元雄良治
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-23590898

  • [Presentation] 多重蛍光MethyLightによるLINE-1のメチル化解析と大腸がんにおけるその臨床的意義2011
    • Author(s)
      松之木愛香, 川上和之, ほか, 源利成
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀(佐賀県)
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] 膵癌細胞におけるgemcitabine誘導性EMTに関連する新規分子の同定2011
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀,佐賀
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 多重蛍光MethyLightによるLINE-1のメチル化解析と大腸がんにおけるその臨床的意義2011
    • Author(s)
      松之木愛香, 川上知之, ほか, 源利成
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀,佐賀
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ゲムシタビン単剤療法の壁への挑戦：新規標的分子の同定と膵癌化学療法への展開2011
    • Author(s)
      島崎猛夫，川上和之，源 利成，ほか
    • Organizer
      第42回日本膵臓学会大会
    • Place of Presentation
      ホテル ニューキャッスル，弘前
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] Glycogen synthase kinase (GSK) 3βは神経膠芽腫の浸潤を促進する2011
    • Author(s)
      近野祐里，ほか，川上和之，源 利成
    • Organizer
      第70回日本癌学会総会学術集会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] Interleukin-1β is a signal for Trefoil factor 2 promoter methylation in gastric preneoplasia.2011
    • Author(s)
      Menheniott TR, O'Connor L, Minamoto T, - 6 -Kawakami K, Tomita H, Fox JG, Wan g TC,Judd LM, Giraud AS
    • Organizer
      DDW 2011
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 膠芽腫の新規治療標的GSK3βに関する基礎研究とトランスレーショナルリサーチ2011
    • Author(s)
      中田光俊, 川上和之, 源利成, ほか
    • Organizer
      第49回日本癌治療学会学術集会
    • Place of Presentation
      名古屋国際会議場,名古屋
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 再発膠芽腫に対するGSK3βを治療標的とした分子標的療法の現状2011
    • Author(s)
      中田光俊，川上和之，源 利成，ほか
    • Organizer
      第70回日本脳神経外科学会学術総会
    • Place of Presentation
      パシフィコ横浜，横浜
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] リンパ節および遠隔転移を伴う大腸がんにおける高頻度のLINE-1低メチル化2011
    • Author(s)
      小竹優範, 川上和之, ほか, 源利成
    • Organizer
      第70回日本癌学会総会学術集会
    • Place of Presentation
      名古屋国際会議場,名古屋
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ゲムシタビン単剤療法の壁への挑戦:新規標的分子の同定と膵癌化学療法への展開2011
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第42回日本膵臓学会大会
    • Place of Presentation
      ホテルニューキャッスル,弘前
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 膠芽腫の新規治療標的GSK3βに関する基礎研究とトランスレーショナルリサーチ2011
    • Author(s)
      中田光俊，川上和之，源 利成，ほか
    • Organizer
      第49回日本癌治療学会学術集会
    • Place of Presentation
      名古屋国際会議場，名古屋
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] 多重蛍光 MethyLight による LINE-1 のメチル化解析と大腸がんにおけるその臨床的意義2011
    • Author(s)
      松之木愛香, 川上和之, 小竹優範, 金子真美, 源 利成
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀(佐賀県)
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] 膵癌に新規治療標的としてのglycogen synthase kinase (GSK)3β:化学療法戦略の新展開2011
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第70回日本癌学会総会学術集会
    • Place of Presentation
      名古屋国際会議場,名古屋
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] HITS (FAM107B): novel heat-shock induced protein as a maker for cancer progression and diagnosis2011
    • Author(s)
      Nakajima H, Minamoto T, Motoo Y
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Hotel Rodos Palace, Rhodes Island, Greece.
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] 膵癌の新規治療標的としてのGlycogen synthase kinase (GSK) 3β：化学療法戦略の新展開2011
    • Author(s)
      島崎猛夫、ほか、川上和之、源利成
    • Organizer
      第７０回日本がん学会総会学術集会
    • Place of Presentation
      名古屋国際会議場、愛知
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 膵癌の新規治療標的としてのglycogen synthase kinase (GSK) 3β:化学療法戦略の新展開2011
    • Author(s)
      島崎猛夫, 川上和之, ほか, 源利成
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] Interleukin-1β is a signal for Trefoil factor 2 promoter methylation in gastric preneoplasia2011
    • Author(s)
      Menheniott TR, Minamoto T, Kawakami K, et al
    • Organizer
      Digestive Disease Week 2011
    • Place of Presentation
      McCormick Place, Chicago, IL, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] リンパ節および遠隔転移を伴う大腸がんにおける高頻度のLINE-1低メチル化2011
    • Author(s)
      小竹優範, 川上和之, ほか, 源利成
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] 切除不能進行膵癌に対するGSK3βを標的とした新規治療戦略2011
    • Author(s)
      島崎猛夫，川上和之，源 利成，ほか
    • Organizer
      JDDW 2011（日本消化器病学会週間 2011）
    • Place of Presentation
      福岡国際センター/福岡サンパレス/福岡国際会議場/マリンメッセ福岡，福岡
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] Deregulated glycogen synthase kinase (GSK) 3β participates in invasion of glioblastoma2011
    • Author(s)
      Chikano Y, et al, Kawakami K, Minamoto T
    • Organizer
      The 6^<th> International Symposium of Institute Network(第6回附置研究所ネットワーク国際シンポジウム)
    • Place of Presentation
      東京ドームホテル,東京
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 膵癌細胞におけるgemicitabine誘導性EMTに関連する新規分子の同定2011
    • Author(s)
      島崎猛夫、ほか、川上和之、源利成
    • Organizer
      第２２回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀、佐賀
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] HITS (FAM107B) : novel heat-shock induced protein as a maker for cancer progression and diagnosis2011
    • Author(s)
      Nakajima H, Minamoto T, et al.
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Hotel Rodeos Palace, Rhodes Island, Greece
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Deregulated glycogen synthase kinase (GSK) 3β participates in invasion of glioblastoma.2011
    • Author(s)
      Chikano Y, Hirose M, et al., Kawakami K, MInamoto T
    • Organizer
      The 6th International Symposium of Institute Network
    • Place of Presentation
      東京医科歯科大学、東京
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] リンパ節および遠隔転移を伴う大腸がんにおける高頻度の LINE-1 低メチル化2011
    • Author(s)
      小竹優範, 川上和之, (他4名) , 源 利成
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-23390321

  • [Presentation] 再発膠芽腫に対するGSK3βを治療標的とした分子標的治療法の現状2011
    • Author(s)
      中田光俊、ほか、川上和之、源利成
    • Organizer
      第７０回日本脳神経外科学会学術総会
    • Place of Presentation
      パシフィコ横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] 再発膠芽腫に対するGSK3βを治療標的とした分子標的療法の現状2011
    • Author(s)
      中田光俊, 川上和之, 源利成, ほか
    • Organizer
      第70回日本脳神経外科学会学術総会
    • Place of Presentation
      パシフィコ横浜,横浜
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 切除不能進行膵癌に対するGSK3βを標的とした新規治療戦略2011
    • Author(s)
      島崎猛夫、ほか、川上和之、源利成
    • Organizer
      日本消化器関連学会機構JDDW(Japan Digestive Disease Week)
    • Place of Presentation
      福岡国際センター、福岡サンパレス、福岡国際会議場、マリンメッセ福岡、福岡
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Deregulated glycogen synthase kinase (GSK) 3b participates in invasion of glioblastoma2011
    • Author(s)
      Chikano Y, et al, Kawakami K, Minamoto T.
    • Organizer
      The 6th International Symposium of Institute Network (第６回附置研究所ネットワーク国際シンポジウム)
    • Place of Presentation
      東京ドームホテル，東京
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] 新規熟ショック誘導性蛋白質(HITS)の発現を利用した癌の診断2011
    • Author(s)
      中島日出夫, 源利成, ほか
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀,佐賀
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Glycogen synthase kinase(GSK)3βは神経膠芽腫の浸潤を促進する2011
    • Author(s)
      近野祐里, ほか, 川上和之, 源利成
    • Organizer
      第70回日本癌学会総会学術集会
    • Place of Presentation
      名古屋国際会議場,名古屋
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 切除不能進行膵癌に対するGSK3βを標的とした新規治療戦略2011
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      JDDW2011(日本消化器病学会週間2011)
    • Place of Presentation
      福岡国際センター/福岡サンパレス/福岡国際会議場/マリンメッセ福岡,福岡
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] HITS (FAM107B):Νovel heat-shock induced protein as a maker for cancer progression and diagnosis2011
    • Author(s)
      Nakajima H, Minamoto T, Motoo Y
    • Organizer
      16^<th> World Congress on Advances in Oncology
    • Place of Presentation
      Rhodes Island, Greece
    • Year and Date
      2011-10-07
    • Data Source
      KAKENHI-PROJECT-23590898

  • [Presentation] 膵癌細胞におけるgemcitabine誘導性EMTに関連する新規分子の同定2011
    • Author(s)
      島崎猛夫，川上和之，源 利成，ほか
    • Organizer
      第22回日本消化器癌発生学会
    • Place of Presentation
      ホテルニューオータニ佐賀，佐賀
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] 膠芽腫の新規治療標的GSK3βに関する基礎研究とトランスレーショナルリサーチ2011
    • Author(s)
      中田光俊、ほか、川上和之、源利成
    • Organizer
      第４９回日本癌治療学会学術集会
    • Place of Presentation
      名古屋国際会議場、愛知
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] Interleukin-1β is a signal for Trefoil factor 2 promoter methylation in gastric preneoplasia2011
    • Author(s)
      Menheniott TR, O'Connor L, Minamoto T,Kawakami K, Tomita H, Fox JG, Wan g TC,Judd LM, Giraud AS
    • Organizer
      DDW 2011
    • Place of Presentation
      McCormick Place, Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23659643

  • [Presentation] Glycogen synthase kinase (GSK) 3βは神経膠芽腫の浸潤を促進する2011
    • Author(s)
      近野祐里、ほか、廣瀬まゆみ、川上和之、源利成
    • Organizer
      第７０回日本がん学会総会学術集会
    • Place of Presentation
      名古屋国際会議場、愛知
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] HITS (FAM107B): novel heat-shock induced protein as a maker for cancer progression and diagnosis.2011
    • Author(s)
      Nakajima H, Minamoto T, Motoo Y.
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Hotel Rodos Palace, Rhodes Island, Greece
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Elevation of rat plasma P-selectin in acute lung injury2011
    • Author(s)
      廣瀬まゆみ, ほか, 川上和之, 源利成
    • Organizer
      日本分子生物学会・第11回春季シンポジウム
    • Place of Presentation
      石川県立音楽堂,金沢
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ゲムシタビン単剤療法への挑戦：新規標的分子の同定と膵癌化学療法への展開2011
    • Author(s)
      島崎猛夫、ほか、川上和之、源利成
    • Organizer
      第４２回日本膵臓学会大会
    • Place of Presentation
      ホテルニューキャッスル、青森
    • Data Source
      KAKENHI-PROJECT-23591955

  • [Presentation] FISH法を用いた大腸癌におけるEGFR遺伝子の増幅の検討2011
    • Author(s)
      大井章史, ほか, 源利成
    • Organizer
      第100回日本病理学会総
    • Place of Presentation
      パシフィコ横浜,横浜
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer.2010
    • Author(s)
      Saito K, Kawakami K, Matsumoto I, Oda M, Watanabe G, Minamoto T
    • Organizer
      101st Annual Meeting of American Association for Cancer Research 2010
    • Place of Presentation
      Walter E. Washington Convention Center, Washington DC, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer2010
    • Author(s)
      Saito K, et al, Kawakami K, Minamoto T
    • Organizer
      101^<st> Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Walter E. Washington Convention Center (U.S.A)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Clinical trial for treatment of recurrent glioblastoma targeting deregulated GSK3β in combination with temozolomide.Glycogen synthase kinase (GSK)3βを分子標的とした再発神経膠芽腫に対する化学療法2010
    • Author(s)
      中田光俊, 川上和之, 源利成, ほか
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IA non-smallcell lung cancer2010
    • Author(s)
      SaitoK, et al, Kawakami K, Minamoto T
    • Organizer
      101^<st> Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Washington Convention Center (U.S.A.)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] 再発膠芽腫に対するGSK3β阻害薬剤を使用した第I/II相臨床試験(Phase I/II clinical trial targeting GSK3β for the recurrent glioblastoma)2010
    • Author(s)
      中田光俊, 川上和之, 源利成, ほか
    • Organizer
      第28回日本脳腫瘍学会学術集会
    • Place of Presentation
      軽井沢プリンスホテルウエスト(長野県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 消化管がん組織検体資源化による進行再発大腸がんに対する抗EGFR分子標的医療の均てん化への取り組み2010
    • Author(s)
      藤田秀人, 川上和之, ほか, 源利成
    • Organizer
      第110回同本外科学会定期学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] TFF2 inhibits tumour growth and is a target for epigenetic silencing in gastric cancer2010
    • Author(s)
      Menheniott T, Minamoto T, Kawakami K, et al.
    • Organizer
      DDW(Digestive Disease Week)2010
    • Place of Presentation
      Ernest N. Morial Convention Center (U.S.A.)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Giraud. TFF2 inhibits tumour growth and is a target for epigenetic silencing in gastric cancer.2010
    • Author(s)
      Menheniott T, Peterson AJ, O'Connor L, Wan g TC, Fox JG, Minamoto T, Kawakami K, Judd LM, Andrew S
    • Organizer
      DDW 2010
    • Place of Presentation
      Ernest N. Morial Convention Center, New Orleans, Louisiana, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2010
    • Author(s)
      Miyashita K, et al, Kawakami K, Minamoto T
    • Organizer
      101^<st> Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Walter E. Washington Convention Center (U.S.A)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用:Project Kの試み2010
    • Author(s)
      小竹優範, 川上和之, ほか, 太田哲生, 源利成
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      海峡メッセ下関(山口県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Distinct DNA methylation profiles and genetic signatures in human colorectal cancer.大腸癌におけるDNAメチル化パターンと選伝子変異の関連2010
    • Author(s)
      小竹優範, 川上和之, ほか, 源利成
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Glycogen synthase kinase 3β inhibition affects methylation status of the 06-methylguanine DNA methyltransferase (MGMT) promoter and MGMT gene expression in human glioma cells2010
    • Author(s)
      llya V.Pyko, 川上和之, 源利成, ほか
    • Organizer
      第11回日本分子脳神経外科学会
    • Place of Presentation
      東北大学医学部艮陵会館,(宮城県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Distinct DNA methylation profiles and genetic signatures in human colorectal cancer.2010
    • Author(s)
      小竹優範, 川上和之, (他4名), 源利成.
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府).
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Role and regulation of glycogen synthase kinase 3β in gemcotabine-induced EMT of pancreatic cancer cells.Gemcitabineによる膵癌細胞のEMTにおけるglycogen synthase kinase(GSK)3βの役割とその制御2010
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第69回日本癌学会学術集会,English Workshop
    • Place of Presentation
      大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用:Project Kの試み2010
    • Author(s)
      小竹優範, 川上和之, ほか, 源利成
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      海峡メッセ下関(山口県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Pathological role for deregulated GSK3β in pancreatic cancer proliferation and invasion2010
    • Author(s)
      Kitano A, et al, Kawakami K, Minamoto T
    • Organizer
      The Joint Symposium of the 5^<th> International Symposium of Institute Network and the International Symposium of Commemorating Inauguration of Kanazawa University Cancer Research Institute
    • Place of Presentation
      KKRホテル金沢(石川県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma2010
    • Author(s)
      Miyashita K, et al, Kawakami K, Minamoto T
    • Organizer
      101^<st> Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Washington Convention Center (U.S.A.)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Pathological role for deregulated GSK3β in pancreatic cancer proliferation and invasion.2010
    • Author(s)
      Kitano A, Shimasaki T, Chikano Y, Nakada M, Higashi T, Ishigaki Y, Sai Y, Miyamoto K, Motoo Y, Kawakami K, Minamoto T
    • Organizer
      The Joint Symposium of the 5thInternational Symposium of Institute Network and the International Symposium of Commemorating Inauguration of Kanazawa University Cancer Research Institute
    • Place of Presentation
      KKRホテル金沢,石川
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 熱ショック誘導性新規がん抑制遺伝子の解析2010
    • Author(s)
      中島日出夫, 川上和之, 源利成, ほか
    • Organizer
      第21回日本消化器癌発生学会
    • Place of Presentation
      軽井沢プリンスホテルウエスト(長野県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Distinct DNA methylation profiles and genetic signatures in human colorectal cancer.大腸癌におけるDNAメチル化パターンと遺伝子変異の関連2010
    • Author(s)
      小竹優範, 川上和之, ほか, 源利成
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] LINE-1 methylation is stable in primary and synchronous metastatic colorectal cancer tissues.2010
    • Author(s)
      松之木愛香, 川上和之, (他3名), 源利成.
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] LINE-1 hypomethylation is a marker of poor prognosis in stage IAnon-small cell lung cancer.2010
    • Author(s)
      斎藤健一郎, 川上和之, (他3名), 源利成.
    • Organizer
      101^<st> Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Washington Convention Center (USA)
    • Year and Date
      2010-04-19
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Effect of GSK3βinhibition agaisnt gemcitabine-induced epithelial-mesenchymal transition and invasive ability of pancreatic cancer cells: its therapuetic implication.2010
    • Author(s)
      Shimasaki T, Ishigaki Y, Takata T, NakamuraY, Kitano A, Kawakami K, Tomosugi N, Minamoto T, Motoo Y.
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society 2010
    • Place of Presentation
      福岡国際会議場,福岡
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Targeting glycogen synthase kinase 3β in adult recurrent glioblastomas2010
    • Author(s)
      Nakada M, Kawakami K, Minamoto T, et al.
    • Organizer
      7^<th> Meeting of Asian Society for Neuro-Oncology
    • Place of Presentation
      JW Marriott Hotel (Korea)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用:Project Kの試み.2010
    • Author(s)
      小竹優範, (他8名), 川上和之, 源利成.
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      海峡メッセ下関(山口県).
    • Year and Date
      2010-07-14
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] LINE-1 methylation is stable in primary and synchronous metastatic colorectal cancer tissues.大腸癌原発巣および転移巣におけるLrNE-1メチル化の検討2010
    • Author(s)
      松之木愛香, 川上和之, ほか, 源利成
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 膠芽腫におけるGSK3β研究の進展とその阻害薬剤を使用した再発膠芽腫に対する第I/II相臨床試験2010
    • Author(s)
      中田光俊, 川上和之, 源利成, ほか
    • Organizer
      第69回日本脳神経外科学会学術総会
    • Place of Presentation
      福岡コンベンションセンター,福岡国際会議場,マリンメッセ福岡(福岡県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] LINE-1 methylation is stable in primary and synchronous metastatic colorectal cancertissues.大腸癌原発巣および転移巣におけるLINE-1メチル化の検討2010
    • Author(s)
      松之木愛香,川上和之, ほか, 源利成
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma.2010
    • Author(s)
      Miyashita K, Kawakami K, Nakada M, Shakoori A, Fujisawa H, Hayashi Y, HamadaJ, Minamoto T
    • Organizer
      101st Annual Meeting of American Association for Cancer Research 2010
    • Place of Presentation
      Walter E. Washington Convention Center, Washington DC, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Effect of GSK3β inhibition agaisnt gemcitabine-induced epithelial-mesenchymal transition and invasive ability of pancreatic cancer cells : its theranuetic implication2010
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et al.
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society 2010(第41回日本膵臓学会大会/第14回国際膵臓学会合同学会)
    • Place of Presentation
      福岡国際会議場(福岡県))
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 膵癌細胞の抗がん剤誘導性上皮-間葉移行とGSK3β阻害による制御機構2010
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第21回日本消化器癌発生学会
    • Place of Presentation
      軽井沢プリンスホテルウエスト(長野県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] 進行再発大腸癌に対するセツキシマブ併用化学療法の治療成績とKRAS遺伝子検索の有用性2010
    • Author(s)
      藤田秀人, ほか, 太田哲生, 源利成
    • Organizer
      第72回日本臨床外科会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] TFF2 inhibits tumour growth and is a target for epigenetic silencing in gastric cancer2010
    • Author(s)
      Menheniott T, Minamoto T, Kawakami K, et al.
    • Organizer
      DDW (Digestive Disease Week) 2010
    • Place of Presentation
      Morial Convention Center (U.S.A.)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用2010
    • Author(s)
      小竹優範, 川上和之, ほか, 太田哲生, 源利成
    • Organizer
      第21回日本消化器癌発生学会
    • Place of Presentation
      軽井沢プリンスホテルウエスト(長野県)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] ヒト消化管がん組織検体資源化によるがん研究と個別化医療への応用2010
    • Author(s)
      小竹優範, 川上和之, ほか, 源利成
    • Organizer
      第21回日本消化器癌発生学会
    • Place of Presentation
      軽井沢プリンスホテル、(長野県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] 熱ショック誘導性新規がん抑制遺伝子の解析2010
    • Author(s)
      中島日出夫, 川上和之, 源利成, ほか
    • Organizer
      第21回日本消化器癌発生学会
    • Place of Presentation
      軽井沢プリンスホテル、(長野県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Pathological role for deregulated glycogen synthase kinase(GSK)3β inpancreatic cancer proliferation and invasion.膵がん細胞の増殖と浸潤におよぼすglycogen sypthase kinase(GSK)3βの病的作用2010
    • Author(s)
      北野綾子, ほか, 川上和之, 源利成
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Pathological role for deregulated glycogen synthase kinase(GSK)3β in glioblastoma proliferation and invasion.神経膠芽腫の増殖と浸潤におよぼすglycogen synthase kinase(GSK)3βの病的作用2010
    • Author(s)
      近野祐里, ほか, 川上和之, 源利成
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
    • Data Source
      KAKENHI-PROJECT-22249051

  • [Presentation] Pathological roles for glycogen synthase kinase (GSK) 3β in proliferation and motility of pancreatic cancer cells2009
    • Author(s)
      北野綾子, 川上和之, 源利成, et al
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 (神奈川県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Glycogen synthase kinase(GSK)3β sustains colon cancer cells survival by modulating JNK-mediated pathway.2009
    • Author(s)
      Jin M, Kawakami K, Shimasaki T, et al., Minamoto T
    • Organizer
      第68回日本癌学会繊学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] LINE-1メチル化解析による大腸がんの予後・抗癌剤感受性診断2009
    • Author(s)
      川上和之, 源利成, ほか
    • Organizer
      第20回消化器癌発生学会総会
    • Place of Presentation
      オリエンタルホテル広島 (広島県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Augmentation of LINE-1 expression is a possible mechanism underling cytotoxic effect of 5-FU in colorectal cancer2009
    • Author(s)
      Kawakami K, et al., Minamoto T
    • Organizer
      第68回日本癌学会総会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Glycogen synthase kinase (GSK) 3β sustains colon cancer cells survival by modulating JNK- mediated pathway2009
    • Author(s)
      Jin MJ, Kawakami K, Minamoto T, et al
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 (神奈川県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] LINE-1メチル化解析による大腸がんの予後・抗癌剤感受性診断.2009
    • Author(s)
      川上和之, 源利成
    • Organizer
      第20回消化器癌発生学会総会:シンポジウム(3)消化器癌診断の新展開
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] DNAメチル化マーカーによる大腸がんの予後・抗癌剤感受性診断.2009
    • Author(s)
      川上和之, 源利成.
    • Organizer
      第17回日本消化器関連学会週間(JDDw 2009)/第51回日本消化器病学会大会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] GSK3βによる膵がん細胞の増殖と浸潤の制御2009
    • Author(s)
      北野綾子, 川上和之, 源利成, ほか
    • Organizer
      第20回消化器癌発生学会総会
    • Place of Presentation
      オリエンタルホテル広島 (広島県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Augmentation of LINE-1 expression is a possible mechanism underling cytotoxic effect of 5-FU in colorectal cancer2009
    • Author(s)
      川上和之, 源利成, et al
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 (神奈川県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] GSK3βを分子標的とした再発GBMに対する第I/II相臨床試験.2009
    • Author(s)
      中田光俊, 源利成, ほか
    • Organizer
      第10回日本分子脳神経外科学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Pathological roles for glycogen synthase kinase(GSK)3β in proliferation and motility of pancreatic cancer cells2009
    • Author(s)
      Kitano A, Shimasaki T, et al., Kawakami K, Minamoto T
    • Organizer
      第68回日本癌学会総会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Glycogen synthase kinase (GSK)-3β inhibition for cancer treatment2009
    • Author(s)
      Minamoto T, Kawakami K, et al
    • Organizer
      第14回日韓がん研究ワークシヨップ
    • Place of Presentation
      ANAクラウンプラザホテル金沢 (石川県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] GSK3βによる膵がん細胞の増殖と浸潤の制御.2009
    • Author(s)
      北野綾子, 島崎猛夫, ほか, 川上和之, 源利成
    • Organizer
      第20回消化器癌発生学会総会:ミニシンポジウム(5)-3消化器癌の分子基盤:浸潤・転移-3
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] GSK3β阻害による抗がん剤誘導性上皮-間葉移行の制御に基づく新規膵癌治療ストラテジー.2009
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第20回消化器癌発生学会総会:シンポジウム(2)消化器癌治療の新展開
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Chemotherapy-induced changes in morphology and invasion ability of pancreatic cancer cells2009
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et al
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 (神奈川県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Allele-specific inhibition of thymidylate synthase expression by small interfering RNA.2009
    • Author(s)
      川上和之, (他4名), 源利成.
    • Organizer
      Annual Meeting 2009 0f the American Association for Cancer Research
    • Place of Presentation
      Colorado Convention Center(USA)
    • Year and Date
      2009-04-20
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Augmentation of LINE-1 expression is apossible mechanism underling cytotoxic effect of 5-FU in colorectal cancer.2009
    • Author(s)
      川上和之, (他4名), 源利成.
    • Organizer
      第68回日本癌学会総会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] DNAメチル化マーカーによる大腸がんの予後・抗癌剤感受性診断.2009
    • Author(s)
      川上和之, 源利成
    • Organizer
      第17回日本消化器関連学会週間(JDDW 2009)/第51回日本消化器病学会大会:シンポジウム6.
    • Place of Presentation
      国立京都国際会館,グランドプリンスホテル京都(京都府)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Allele-specific inhibition of thymidylate synthase expression by small interfering RNA.2009
    • Author(s)
      Kawakami K, et al., Minamoto T.
    • Organizer
      100^<th> Annual Meeting of the American Association for Cancer Research 2009
    • Place of Presentation
      Denver, CO(U.S.A)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] ヒト消化管がん組織検体資源化の試み:がん研究とがんの個別化医療への応用.2009
    • Author(s)
      山下要, 川上和之, ほか, 源利成
    • Organizer
      第47回日本がん治療学会総会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Glycogen synthase kinase(GSK)-3β inhibition for cancer treatment.2009
    • Author(s)
      Minamoto T, Kawakami K
    • Organizer
      第14回日韓がん研究ワークショップ
    • Place of Presentation
      ANAクラウンプラザホテル金沢(石川県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Chemotherapy-induced changes in morphology and invasion ability of pancreatic cancer cells2009
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et al.
    • Organizer
      第68回日本癌学会総会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] ヒト消化管がん組織検体資源化の試み : がん研究とがんの個別化医療への応用2009
    • Author(s)
      山下要, 川上和之, 源利成, ほか
    • Organizer
      第47回日本がん治療学会総会学術集会
    • Place of Presentation
      パシフィコ横浜 (神奈川県)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] LINE-1メチル化解析による大腸がんの予後・抗癌剤感受性診断.2009
    • Author(s)
      川上和之, 源利成.
    • Organizer
      第20回消化器癌発生学会総会
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Year and Date
      2009-11-26
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Allele-specific inhibition of thymidylate synthase expression by small interfering RNA2009
    • Author(s)
      川上和之, 源利成, et al
    • Organizer
      Annual Meeting 2009 of the American Association for Cancer Research
    • Place of Presentation
      Colorado Convention Center, Denver, CO, (U.S.A)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] GSK3β阻害剤と塩酸ゲムシタビンの併用による膵癌の新規治療戦略と分子基盤.2009
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第40回日本膵臓病学会大会,シンポジウム2
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] DNAメチル化マーカーによる大腸がんの予後・抗癌剤感受性診断2009
    • Author(s)
      川上和之, 源利成, ほか
    • Organizer
      第17回日本消化器関連学会週間 (JDDW 2009)
    • Place of Presentation
      国立京都国際会館 (京都府)
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] 再発神経膠芽腫に対するGSK3βを分子標的としたPhase I/II臨床試験.2009
    • Author(s)
      中田光俊, 源利成, ほか
    • Organizer
      第68回日本脳神経外科学会総会:シンポジウム4グリオーマの新たな治療戦略
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Detection of active fraction of GSK3βin cancer cells by non-radioisotopic in vitro kinase assay.2008
    • Author(s)
      Mai W, Kawakami K, et al, Minamoto T
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008
    • Author(s)
      塑上和之, ほか, 源利成
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発.2008
    • Author(s)
      川上和之, (他4名), 源利成.
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府 亀の井ホテル(大分県)
    • Year and Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008
    • Author(s)
      川上和之, ほか, 源利成
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer.2008
    • Author(s)
      川上和之, (他5名), 源利成.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego Convention Center (USA)
    • Year and Date
      2008-04-14
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] 慢性進行性疾患の創薬標的GSK3βの消化器がんにおける発現, 活性と機能解析2008
    • Author(s)
      川上和之, ほか, 源利成
    • Organizer
      第16回日本消化器関連学会週間(JDDW2008)/第50回日本消化器病学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] 膵癌における新しい分子標的としてのGSK3βとその関連遺伝子群の解析2008
    • Author(s)
      島崎猛夫, 石垣靖人, 中谷直喜, 中島日出夫, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
    • Organizer
      第6回日本臨床腫瘍学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Distinct pathologic property of glycogen synthase kinase 3β (GSK3β) in gastrointestinal, pancreatic and liver cancers.胃がん, 大腸がん, 膵がんと肝がんに共通するglycogen synthase kinase 3β(GSK3β)の病的作用2008
    • Author(s)
      Mai W, Miyashita K, Shakoori A, Shimasaki T, Yasumoto K, Yoshiharu Motoo, Kawakami K, Minamoto T.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 膵癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer : basic analysis for future clinical trial2008
    • Author(s)
      Shimasaki T, Kawakami K, et.al., Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] 慢性進行性疾患の創薬標的GSK3Pの消化器がんにおける発現, 活性と機能解析.2008
    • Author(s)
      川上和之, ほか, 源 利成
    • Organizer
      第16回日本消化器関連学会週間(JDDW 2008)/第50回日本消化器病学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 非小細胞肺癌におけるLINE-1低メチル化は新規の予後因子である2008
    • Author(s)
      Saito K, Kawakami K, et.al., Minamoto T
    • Organizer
      第67向日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Inhibition of GSK3β activity attenuates proliferation of human colon cancer cells in rodents2008
    • Author(s)
      Minamoto T, Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 慢性進行性疾患の創薬標的GSK3βの消化器がんにおける発現, 活性と機能解析. 第16回日本消化器関連学会週間(JDDW 2008)2008
    • Author(s)
      川上和之, 島崎猛夫, 源利成
    • Organizer
      第50回日本消化器病学会大会 : ワークショップ13
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発2008
    • Author(s)
      川上和之, 金明姫, 斉藤健一郎, 麦威, 宮下勝吉, 源利成
    • Organizer
      第19回日本消化器癌発生学会総会ミニシンポジウム(8)
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 非小細胞肺癌におけるLINE-1低メチル化は新規の予後因子である2008
    • Author(s)
      Saito K, Kawakami K., et al, Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008
    • Author(s)
      Kawakami K, Jin MJ, Saito K, Miyashita K, Mai W, Watanabe Go, Minamoto T.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/β-catenin signaling in human colorectal cancer2008
    • Author(s)
      Minamoto T, Yamashita K, Kawakami K.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] GSK3β inhibition sensitizes glioblastoma cells to chemotherapy and radiation by modulating p53 and Rb pathways. GSK3β阻害によるp53 とRb 経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾2008
    • Author(s)
      Miyashita K, Nakada M, Fujisawa H, Mai W, Kawakami K, Jun-ichiro Hamada, Minamoto T.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 遺伝子多型とアレル欠失を利用した癌特異的治療開発.2008
    • Author(s)
      川上和之, 源利成ほか
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/p-catenin signaling in human colorectal cancer.2008
    • Author(s)
      Minamoto T, et al Kawakami K
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] GSK3β阻害によるp53とRb経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾.2008
    • Author(s)
      Miyashita K, Kawakami K., et al, Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 胃がん, 大腸がん, 膵がんと肝がんに共通するglycogen synthase kinase 3β(GSK3β)の病的作用2008
    • Author(s)
      Mai W, et.al., Kawakami K, Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/β-catenin signaling in human colorectal cancer2008
    • Author(s)
      Minamoto T Kawakami K, et al
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Detection of active fraction of GSK3 in cancer cells by non- radioisotopic in vitro kinase assay2008
    • Author(s)
      Mai W, Kawakami K, et.al., Minamoto T
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, U.S.A
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Novel molecular mechanism and clinical relevance of deregulated Wnt/β-catenin signaling in human colorectal cancer2008
    • Author(s)
      Minamoto T, et.al., Kawakami K
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for thepatients with primary colorectal cancer.2008
    • Author(s)
      Kawakami K, et al Minamoto T
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008
    • Author(s)
      Kawakami K, et.al., Minamoto T
    • Organizer
      Annual Meeting 2008 of the Amedcan Association for Cancer Research
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] LINE-1 hypomethylation is a novel prognostic factor in non-small cell lung cancer.2008
    • Author(s)
      斎藤健一郎, 川上和之, (他3名), 源利成.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] LINE-1 hypomethylation is a novel prognostic factor in non-small cell lung cancer. 非小細胞肺癌におけるLINE-1 低メチル化は新規の予後因子である2008
    • Author(s)
      Saito K, Kawakami K, Matsumoto I, Oda M, Watanabe G, Minamoto T.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 神経膠芽腫におけるGSK3βの発現・活性と機能解析.2008
    • Author(s)
      宮下勝吉, 川上和之, 源利成, ほか
    • Organizer
      第26回日本脳腫瘍病理学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Inhibition of GSK3β activity attenuates proliferation of human colon cancer cells in rodents.2008
    • Author(s)
      Minamoto T, Kawakami K, et al
    • Organizer
      Annual Meeting 2008 of the AmericanAssociation for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer : basic analysis for future clinical trial2008
    • Author(s)
      Shimasaki T, Ishigaki, Y Nakaya N, Nakajima H, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 慢性進行性疾患の創薬標的GSK3βの消化器がんにおける発現, 活性と機能解析2008
    • Author(s)
      川上和之, 源利成ほか
    • Organizer
      第16回日本消化器関連学会週間(JDDW 2008)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] GSK3β阻害によるp53とRb経路を介した神経膠芽腫細胞の抗がん剤および放射線感受性の修飾2008
    • Author(s)
      Miyashita K, Kawakami K. et.al., Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] 胃がん, 大腸がん, 譚がんと肝がんに共通するglycogen synthase kinase 3β(GSK3P)の病的作用.2008
    • Author(s)
      Mai W, et al, Kawakami K. Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Detection of active fraction of GSK3β in cancer cells by non-radioisotopic in vitro kinase assay2008
    • Author(s)
      Mai W, Shakoori A, Miyashita K, Zhang B, Motoo Y, Kawakami K, Takahashi Y, Minamoto T.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U.S.A
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with primary colorectal cancer2008
    • Author(s)
      Kawakami K, Minamoto T, et al
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA, U. S. A.
    • Data Source
      KAKENHI-PROJECT-20390353

  • [Presentation] Combined effect of gemcitabine and GSK3βinhibitor against pancreatic cancer : basic analysis for future clinical trial.2008
    • Author(s)
      Shimasaki T, Kawakami K., et al, Minamoto T
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Inhibition of GSK3βactivity attenuates proliferation of human colon cancer cells in rodents.2008
    • Author(s)
      Minamoto T, et al Kawakami K.
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      San-Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 膵癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008
    • Author(s)
      島崎猛夫, 石垣靖人, 夏啓勝, 中谷直喜, 友杉直久, 田中卓二, 麦威, 川上和之, 源利成, 元雄良治
    • Organizer
      第19回日本消化器癌発生学会総会ミニシンポジウム
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Inhibition of GSK3I3 activity attenuates proliferation of human colon cancer cells in rodents2008
    • Author(s)
      Minamoto T, et.al. ; Kawakami K
    • Organizer
      Annual Meeting 2008 of the American Association for Cancer Research
    • Place of Presentation
      SanDiego,U.S.A
    • Data Source
      KAKENHI-PROJECT-20015018

  • [Presentation] 神経膠芽腫におけるGSK3βの発現・活性と機能解析2008
    • Author(s)
      宮下勝吉, 中田光俊, 吉田優也, 藤沢弘範, 林裕, 川上和之, 源利成, 濱田潤一郎
    • Organizer
      第26回日本脳腫瘍病理学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 騨癌の臨床試験を目指したGSK3β阻害剤と塩酸ゲムシタビンの併用療法に関する基礎的解析2008
    • Author(s)
      島崎猛夫, 川上和之, 源利成, ほか
    • Organizer
      第19回日本消化器癌発生学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer:GSK3β as a new therapeuutic target.2007
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Presentation] Wntシグナル制御破綻に関わる新しい分子細胞機構の解明と大腸がん制御への展開2007
    • Author(s)
      源利 成, ほか, 高橋 豊, 川上 和之.
    • Organizer
      第62回日本消化器外科学会定期学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] mRNA expression of gamma glutamyl hydrolase(GGH)is negatively associated with DNA methylation status in primary colorectal cancer2007
    • Author(s)
      Kawakami K, Ruszkiewicz A, Fukushima M, Minamoto T, Iacopetta B.
    • Organizer
      Annual Meeting 2007 of the American Association for Cancer Research
    • Place of Presentation
      Los Angels, CA
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancerresulting in altered gene expression Profiles2007
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et. al.
    • Organizer
      The Second Meeting of Asian-Oceanic Pancreatic Association (AOPA)
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-18
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitor against human pancreas cancer : GSK3β as a new therapeutic molecular target2007
    • Author(s)
      Shimasaki T, Ishigaki Y, Zhao X, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
    • Organizer
      Annual Meeting of American Pancreatic Association
    • Place of Presentation
      Chicago, Illinois, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Expression,deregulated activity and pathologic role of GSK3β in gastrointestinall,pancreas and liver cancers.2007
    • Author(s)
      Mai W, et. al., Kawakami K, Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Presentation] Inhibition of glycogen synthase kinase 3β (GSK3β) attenuates proliferation of human colon cancer cells in rodents2007
    • Author(s)
      Minamoto T, et. al., Takahashi Y, Kawakami K.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Inhibition of glycogen synthase kinase 3β(GSK3β)attenuates proliferation of human colon cancer cells in rodents2007
    • Author(s)
      Minamoto T, Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Combined effect of gemcitabine and GSK3β inhibitor against pancreatic cancer resulting in altered gene expression profiles.2007
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et. al.
    • Organizer
      The Second Meeting of Asian-Oceanic Pancreatic Association (AOPA)
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-18
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Presentation] GSK3β, a novel therapeutic target for gastrointestinal cancer2007
    • Author(s)
      Minamoto T
    • Organizer
      Joint International Symposium on Tumor Biology in Kanazawa 2007 and Molecular & Cellular Targeting Translational Oncology Center
    • Place of Presentation
      Kanazawa, Japan
    • Year and Date
      2007-01-25
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 消化器がんの新しい治療標的GSK3βの発現, 活性, 機能解析2007
    • Author(s)
      川上和之, 麦威, 島崎猛夫, 宮下勝吉, 安本和生, 高橋豊, 大井章史, 元雄良治, 源利成
    • Organizer
      第18回日本消化器がん発生学会総会W2
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 塩酸ゲムシタビンとGSK3β阻害薬の膵癌細胞への抗腫瘍効果とその分子機構2007
    • Author(s)
      島崎猛夫, 中島日出夫, 石垣靖人, 本西哲, 友杉直久, 田中卓二, 川上和之, 源利成, 元雄良治
    • Organizer
      第38回日本膵臓学会大会シンポジウム : 膵癌の基礎と臨床
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Deregulated GSK3β activity in colorectal cancer: its association with tumorcell survival and Proliferation2007
    • Author(s)
      Minamoto T, et. al., Takahashi Y, Kawakami K.
    • Organizer
      Annual Meeting 2007 of the American Association for Cancer Research
    • Place of Presentation
      アメリカ合衆国ロサンジェルス
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 膵癌に対する塩酸ゲムシタビンとGSK3β阻害剤併用の抗腫瘍効果とその分子機構2007
    • Author(s)
      島崎 猛夫, 川上 和之, 源 利成, ほか.
    • Organizer
      第18回目本消化器がん発生学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 消化器がんの新しい治療標的GSK3βの発現,活性,機能解析2007
    • Author(s)
      川上 和之, ほか, 高橋 豊, 源 利成.
    • Organizer
      第18回日本消化器がん発生学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Inhiition of synthase kinase 3β (GSK3β) in glioblastoma attenuates tumor cells'viability and induces apoptosis depending on p53.2007
    • Author(s)
      Miyashita K, et. al., Kawakami K, Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer : GSK3β as a new therapeutic target2007
    • Author(s)
      Shimasaki T, Ishigaki Y, Nakajima H, Tomosugi N, Tanaka T, Mai W, Kawakami K, Minamoto T, Motoo Y.
    • Organizer
      第66 回日本癌学会学術総会English Workshops 14 Kinase Inhibitors
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients withcolorectal cancer2007
    • Author(s)
      Kawakami K, et. al., Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Methylation level of LINE-1 repeats as a prognostic factor for the patients with colorectal cancer.2007
    • Author(s)
      Kawakami K, et. al., Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18659380

  • [Presentation] Synergistic effect of gemcitabine and GSK3β inhibitors against human pancreas cancer: GSK3β as a new therapeutic target2007
    • Author(s)
      Shimasaki T, Kawakami K, Minamoto T, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Inhibition of glycogen synthase kinase 3β(GSK3β) in glioblastoma attenuatestumor cells'viability and induces apoptosis depending on p532007
    • Author(s)
      Miyashita K, et. al., Kawakaml K, Minamoto T.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] Wntシグナル制御破綻に関わる新しい分子細胞機構の解明と大腸がん制御への展開2007
    • Author(s)
      源利成, 山下要, 高橋豊, 川上和之
    • Organizer
      第62回日本消化器外科学会定期学術集会シンポジウム1
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 塩酸ゲムシタビンとGSK3β阻害薬の膵癌細胞への抗腫瘍効果とその分子機構2007
    • Author(s)
      島崎 猛夫, 源 利成, ほか.
    • Organizer
      第38回日本膵臓学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-18390363

  • [Presentation] 膵癌に対する塩酸ゲムシタビンとGSK3β阻害剤併用の抗腫瘍効果とその分子機構2007