ITOH Fumio 伊東文生

Researcher Number	90223180
Other IDs
External Links
Affiliation (Current)	2022: 聖マリアンナ医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2009 – 2022: St.Marianna University School of Medicine, 医学部, 教授 2003 – 2007: Sapporo Medical University, School of Medicine, Professor, 医学部, 教授 2004: Saint Mariana Medical University, Department of Gastroenterology and Hepatology, Professor, 医学部, 教授 2003: 聖マリアンナ医科大学, 教授 1995 – 2002: 札幌医科大学, 医学部, 講師 1993 – 1994: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Biological Sciences / Gastroenterology / Basic Section 52010:General internal medicine-related / Tumor diagnostics Except Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52010:General internal medicine-related / Basic Section 09070:Educational technology-related
Keywords	Principal Investigator マトリライシン / 消化器癌 / DNAメチル化 / 大腸癌 / 浸潤 / 診断 / 治療 / レチノイン酸 / 転移 / メチル化 … More / 潰瘍性大腸炎 / 早期発見 / 膵癌 / DNAアレイ / Bcl-2 / HBV / 肝癌 / ウイルスゲノム組み込み / 生体機能情報 / 分子腫瘍学 / MCA法 / アポトーシス / 早期診断 / 分子マーカー / DFNA5 / CpGアイランド / ヒストンアセチル化 / エピジェネティック / 染色体不安定性 / SNP / 治療標的 / 糞便 / リスク診断 / 食道癌 / 化学療法 / 効果予測 / 網羅的メチル化解析 / 科学療法 / マトリックスメタロプロテアーゼ / TIMP / PCR / 免疫組織染色 / TIMP-1 / TIMP-2 / 潰瘍形成 / Matrilysin / Matrix metalloproteinase / RT-PCR / Immunostaining / ulcerative colitis / extracellular matrix / 予後 / 遺伝子発現 / GASTROINTESTINAL CANCER / MATRILYSIN / INVASION / METASTASIS / PROGNOSIS / DIAGNOSIS / GENE EXPRESSION / 消化管間葉系腫瘍 / VEGF受容体 / 悪性度 / 遺伝子不安定性 / GIST / cDNA array / VEGF recepter / malignant potential / diagnosis / スクリーニング / 便 / 血清 / DNAテスト / Colorectal cancer / Screening / DNA methylation / Stool / Serum / エピゲノム / DNA組み込み / 血液診断 / ヒトパピローマウイルス / 血中可視化 / 子宮頸癌 … More Except Principal Investigator DNAメチル化 / 消化器癌 / 胃癌 / 遺伝子不安定性 / 消火器癌 / 早期診断 / RT-PCR法 / RDA法 / 胃がん / 連鎖解析 / 罹患同胞対法 / マイクロサテライトマーカー / SNPs / 食道癌 / ゲノム / ムチン遺伝子 / 胃前癌病変 / mucin genes / gastric pre-cancerous lesions / gastric cancer / methylation / 発癌 / SNP / MSI / p16 / メチル化 / DNA methylation / CIMP / CHFR / H. pylori / 膵炎 / PCR / モノクローナル抗体 / MUSE11 / 膵癌 / 腫瘍細胞 / ムチン抗原遺伝子 / GalNAcトランスフェラーゼ / アンチセンス抑制 / O-グリカン / 免疫遺伝子療法 / 家族集積性胃癌 / 新遺伝子 / DNA解析 / 遺伝子解析 / がん遺伝子 / 全ゲノムスキャニング / DNA多型マーカー / 発がん / 遺伝要因 / chromosomal instability (CIN) / CINアレイ / 胃潰瘍 / COX-2 / COX2 / ピロリ菌 / スナネズミ / 消化性潰瘍 / 放射線化学療法 / 食道扁平上皮癌 / バイオマーカー / homologous recombination / 食道がん / 肝細胞癌 / Sorafenib / 治療効果予測 / VEGFR / PDGFR / pyrosequencing / HPV / エピゲノム / オミクス解析 / 胆汁うっ滞 / 細胞骨格 / チロシン脱リン酸化酵素 / PTPH1遺伝子 / PTPH1 / c-myc / 染色体9番長腕31領域 / Bile stasis / Cytoskeletal protein / Protein tyrosine phosphatase / PTPH1 gene / 腸上皮化生 / 腸型胃癌 / バレット食道 / 分子機構解析 / Intestinal metaplasia / Barett esohagus / DNA修復遺伝子 / メチレーション / メチレ-ション / genomic instability / DNA repair genes / Barrett癌 / ムチン / intestinalization / 拡大内視鏡 / pit pattern / ムチン, / Barrett's adenocarcinoma / mucin / sulfo-Lewis^a / 遺伝子多型 / 相関解析 / マイクロサテライト / 罹患同胞対 / 連鎖 / 相関 / 全ゲノムスキャン / 多因子疾患 / 全ゲノムスクリーニング / LOD値 / genome / polymorphism / linkage / association / microsatellite / マイクロサテライト不安定性 / 免疫学的診断 / 癌ワクチン / 標的遺伝子変異 / β2-マイクログロブリン / 変異オリゴペプチド / Microsatellite instability / Gastrointestinal tumor / Immunological diagnosis / Cancer vaccine / 細胞周期 / 癌抑制遺伝子 / 肝発癌 / 発癌危険因子 / 発癌生体マーカー / 発癌高危険群 / 発癌予測マーカー / 肝癌 / 細胞周期制御遺伝子 / cell cycle / suppressor gene / hepatocarcinogenesis / early diagnosis / risk factor for carcinogenesis / bio-marker for carcinogenesis / エピジェネティクス / 分子標的治療 / ヒストン / メチル化異常 / 癌発生 / 前癌病変 / Genetic instability / Epigenetics / Molecular target therapy / Gastrointestinal cancer / メチル化阻害剤 / ヒストン脱アセチル化剤 / 抗癌剤感受性 / タキサン / ヒストン脱アセチル化 / CpGアイランド / CHFR遺伝子 / チェックポイント / gastrointestinal cancer / methylation inhibitor / histone acetylation / anti-cancer drug sensitivity / taxane / EBV / DNA組み込み / 間質細胞 / ゲノム解析 / ゲノム多様性 / 胃洗浄廃液 / 人工知能 / 新型ゲノムデータ / 革新的胃癌統合医療 / 内視鏡AI / 内視鏡的粘膜下層剥離術 / トレーニングシステム / 視線追跡装置 / MRシステム / Mixed Reality Less

人工知能・新型ゲノムデータ駆動型アプローチに基づく革新的胃癌統合医療の創成
- Principal Investigator
  
  山本博幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  St. Marianna University School of Medicine
ウイルスゲノム組み込みと生体機能情報のリアルタイム血中可視化による子宮頸癌の制御Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  St. Marianna University School of Medicine
視線追跡装置を用いた消化器内視鏡治療技術の可視化によるトレーニングシステム開発
- Principal Investigator
  
  前畑忠輝
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 09070:Educational technology-related
- Research Institution
  St. Marianna University School of Medicine
臨床検体から同定したピロリ菌ゲノム異常の時空間的な解明に基づく胃癌の革新的制御
- Principal Investigator
  
  山本博幸
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  St. Marianna University School of Medicine
ウイルスゲノム組み込みと生体機能情報のリアルタイム血中可視化による革新的肝癌制御Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  St. Marianna University School of Medicine
Elucidation and regulation of gastric carcinogeneis based on the next-generation integrated analysis of DNA integration and stromal cells
- Principal Investigator
  
  Yamamoto Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
Suppression of hepatocarcinogeneis based on the elucidation of HBV integration and epigenome alterations analyzed by G-NaVIPrincipal Investigator
- Principal Investigator
  
  Itoh Fumio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  St. Marianna University School of Medicine
DSB-HR diagnostic system predicting the sensitivity for chemoradiation therapy in esophageal cancer
- Principal Investigator
  
  Maehata Tadateru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of molecular diagnostic system for the prediction of therapeutic effect in liver cancer
- Principal Investigator
  
  Okuse Chiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
Integrated analysis of HPV integration and epigenome for early diagnosis, treatment and prevention of esophageal cancer
- Principal Investigator
  
  Yamamoto Hiroyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
COX-2 gene promoter methylation in patients infected with Helicobacter pylori.
- Principal Investigator
  
  YASUDA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
Identification of DNA methylation changes in esophageal cancer before/after chemoradiation therapy using an MCA-microarray and bisulfate pyrosequencingPrincipal Investigator
- Principal Investigator
  
  ITOH Fumio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
膵癌スクリーニングを目的とした糞便中メチル化診断Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  St.Marianna University School of Medicine
膵癌治療の標的となる染色体不安定性機構起因分子の解明Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
DEVELOPMENT OF A NOVEL EPIGENETIC SCREENING METHOD FOR DETECTING THE COLORECTAL CANCERPrincipal Investigator
- Principal Investigator
  
  ITOH Fumio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  ST.MARIANNA UNIVERSITY SCHOOL OF MEDICINE
エピジェネティックな異常を標的とした新しい消化器癌診断法の開発Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
Analysis of gene expression in GIST by cDNA arrayPrincipal Investigator
- Principal Investigator
  
  ITOH Fumio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  ST.MARIANNA UNIVERSITY SCHOOL OF MEDICINE
DNAメチル化を用いた遺伝子診断法によるがんの早期診断Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
消化器癌における染色体不安定性検出DNAアレイの開発
- Principal Investigator
  
  吉田幸成
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Application of DNA methylation analysis to tretment of gastrointestinal cancer.
- Principal Investigator
  
  YOSHIDA Yukinari
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
DNAメチル化を用いた遺伝子診断法による早期診断法の確立Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
MATRILYSIN AS A MARKER FOR AGGRESSIVE GASTROINTESTINAL CANCERPrincipal Investigator
- Principal Investigator
  
  ITOH Fumio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Promoter region hypermethylation of cell cycle related gene in hepatocarcinogenesis
- Principal Investigator
  
  SASAKI Shigeru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Microsatellite instability and aberrant methylation in gastrointestinal cancer and its application to molecular target therapy
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Analysis of molecular mechanism of premalignant lesion of the stomach using genomic instability and new mucin gene.
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Genome-wide analyses to identify genes involved in gastric cancer
- Principal Investigator
  
  SASAZUKI Tekehiko
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  International Medical Center of Japan
  Kyushu University
Immunelogical diagnosis of MSI-positive gastrointestinal cancer and application for cancer vaccine
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
罹患同胞対法を用いた胃がん関連遺伝子の解明
- Principal Investigator
  
  SASAZUKI Tekehiko
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
A role of sulfated carbohydrate chain in carcinogenesis of Barrett's esophagus and development of enzymeimmunoassay for sulfomucin.
- Principal Investigator
  
  ENDO Takao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The first department of internal medicine, Sapporo Medical University
家族集積性胃癌関連遺伝子のRDA法による同定
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
AnalysIs of molecular mechanism of gastric pre-cancerous lesions by using new mucin genes
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Relation of matrixmetalloproteinases and infalammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  ITOH Fumio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
GalNAc:ポリペプチド・トランスフェラーゼの発現抑制による癌治療法の開発
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
マトリライシン(MMP-7)の発現制御による大腸癌の転移抑制に関する研究Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
マトリライシン(MMP-7)の発現抑制による大腸癌浸潤抑制の基礎的検討Principal Investigator
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Molecular biological analysis of cytoskeletal associated protein in bile stasis.
- Principal Investigator
  
  TANDA Mariko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University, School of Medicine
膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University

All 2018 2017 2016 2014 2013 2012 2011 2010 2009 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] Cell Signaling & Molecular Targets in Cancer2011
- Author(s)
  Yasuda H, Itoh F
- Total Pages
  328
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23590928
[Book] 内科学2003
- Author(s)
  伊東文生
- Total Pages
  2
- Publisher
  朝倉書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] GNAS-mutated carcinoma arising from gastric foveolar metaplasia in the duodenum after 9 years of observation.2018
- Author(s)
  Matsuo Y, Yamamoto H, Sato Y, Oikawa R, Maehata T, Fujino T, Yahagi N, Yasuda H, Takagi M, Itoh F.
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 11 Pages: 391-395
- DOI
  10.1007/s12328-018-0856-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15435
[Journal Article] Endoscopic small-capacity forceps increase the pathological diagnosis of gastric indefinite neoplasia.2018
- Author(s)
  Matsuo Y, Yasuda H, Kato M, Kiyokawa H, Ozawa M, Sato Y, Ikeda Y, Ozawa SI, Yamashita M, Fujino T, Yamamoto H, Takagi M, Itoh F.
- Journal Title
  
  Turk J Gastroenterol
  
  Volume: 29 Pages: 481-487
- DOI
  10.5152/tjg.2018.17347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15435
[Journal Article] An updated review of gastric cancer in the next-generation sequencing era: Insights from bench to bedside and vice versa.2014
- Author(s)
  Yamamoto H (他14名), Nosho K, Shinomura Y
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 20 Pages: 3927-3937
- DOI
  10.3748/wjg.v20.i14.3927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23590928, KAKENHI-PROJECT-25460937, KAKENHI-PROJECT-25670371
[Journal Article] COX-2 gene promoter methylation in patients infected with Helicobacter pylori2013
- Author(s)
  Michikawa Y, Yasuda H, Watanabe Y, Oikawa R, Ohishi Y, Maehata T, Itoh F
- Journal Title
  
  Clinical Medicine Insights : Gastroenterology
  
  Volume: 6 Pages: 13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Aberrant DNA methylation status of DNA repair ge- nes in breast cancer treated with neoadjuvant chemotherapy2013
- Author(s)
  Watanabe Y, Maeda I, Oikawa R, Wu W, Tsuchiya K, Miyoshi Y, Itoh F, Tsugawa K, Ohta T
- Journal Title
  
  Genes Cells
  
  Volume: 18 Pages: 1120-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] COX-2 gene promoter methylation in patients infected with Helicobacter pylori.2013
- Author(s)
  Michikawa Y, Yasuda H, Watanabe Y, Oikawa R, Ohishi Y, Maehata T, Itoh F
- Journal Title
  
  Clinical Medicine Insights: Gastroenterology
  
  Volume: 6 Pages: 13-19
- DOI
  10.4137/cgast.s11917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps2012
- Author(s)
  Ishigoooka S, Nomoto M, Obinata N, Oishi Y, Sato Y, Nakatsu S, Suzuki M, Ikeda Y, Maehata T, Kimura T, Watanabe Y, Nakajima T, Yamano HO, Yasuda H, Itoh F
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18 Pages: 4308-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Change in levels of hepatitis B virus in patients positive for low-titer hepatitis B surface antigen2012
- Author(s)
  Okuse C, Yotsuyanagi H, Yamada N, Ikeda H, Kobayashi M, Fukuda Y, Takahashi H, Matsunaga K, Matsumoto N, Okamoto M, Ishii T, Sato A, Koike K, Suzuki M, Itoh F
- Journal Title
  
  Hepatol Res
  
  Volume: 42 Pages: 1236-1240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer2012
- Author(s)
  Oishi Y, Watanabe Y, Yoshida Y, Sato Y, Hiraishi T, Oikawa R, Maehata T, Suzuki H, Toyota M, Niwa H, Suzuki M, Itoh F
- Journal Title
  
  Tumor Biol
  
  Volume: 33 Pages: 383-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma2012
- Author(s)
  Hama R, Watanabe Y, Shinada K, Yamada Y, Ogata Y, Yoshida Y, Tamura T, Hiraishi T, Oikawa R, Sakurai J, Maehata T, Koizumi H, Itoh F
- Journal Title
  
  Tumor Biol
  
  Volume: 33 Pages: 2031-2040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] A New Detection Method for Integration of Hepatitis B virus DNA in PLC/PRF/5 Cells2012
- Author(s)
  Hiraishi T, Watanabe Y, Oikawa R, Hara M, Kiyokawa H, Yoshida Y, Yamada N, Okuse C, Suzuki M, Yotsuyanagi H, Itoh F
- Journal Title
  
  Journal of St.Marianna University
  
  Volume: 3 Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps.2012
- Author(s)
  Ishigoooka S, Nomoto M, Obinata N, Oishi Y, Sato Y, Nakatsu S, Suzuki M, Ikeda Y, Maehata T, Kimura T, Watanabe Y, Nakajima T, Yamano HO, Yasuda H, Itoh F.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 18 Pages: 4308-4316
- DOI
  10.3748/wjg.v18.i32.4308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer2011
- Author(s)
  Watanabe Y, Castoro RJ, Kim HS, North B, Oikawa R, Hiraishi T, Ahmed SS, Chung W, Cho M-Y, Toyota M, Itoh F, Estecio M R. H., Shen L, Jelinek J, Issa J-P J
- Journal Title
  
  PLoS ONE
  
  Volume: 6(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590797
[Journal Article] Comparison of the effects of omeprazole and rabeprazole on ticlopidine metabolism in vitro2011
- Author(s)
  Kinoshita Y,Matsumoto N,Watanabe M,Takeba Y,Yoshida Y,Ohba K,Suzuki S,Itoh F,Kobayashi S
- Journal Title
  
  J Pharm Sci
  
  Volume: 117 Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Gastric wash-based molecular testing for antibiotic resistance in Helicobacter pylori2011
- Author(s)
  Baba S, Oishi Y, Watanabe Y, Oikawa R, Morita R, Yoshida Y, Hiraishi T, Maehata T, Nagase Y, Fukuda Y, Nakazawa M, Ishigouoka S, Hattori N, Suzuki H, Toyota M, Niwa H, Suzuki M, Itoh F
- Journal Title
  
  Digestion
  
  Volume: 84 Pages: 299-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] Prospective study of definitive chemoradiotherapy with S-1 and nedaplatin in patients with stageII/III(non-T4) esophageal cancer2011
- Author(s)
  Tsuda T, Inaba H, Miyazaki A, Izawa N, Hirakawa M, Watanabe Y, Kitajima S, Hoshikawa Y, Gomi H, Kimura M, Itoh F
- Journal Title
  
  Esophagus
  
  Volume: 8 Pages: 45-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590797
[Journal Article] HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression2011
- Author(s)
  Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T
- Journal Title
  
  Cancer Res
  
  Volume: 71(17) Pages: 5621-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590797
[Journal Article] Gastric wash-based molecular testing for antibiotic resistance in helicobacter pylori2011
- Author(s)
  Baba S, Oishi Y, Watanabe Y, Oikawa R, Morita R, Yoshida Y, Hiraishi T, Maehata T, Nagase Y, Fukuda Y, Nakazawa M, Ishigouoka S, Hattori N, Suzuki H, Toyota M, Niwa H, Suzuki M, Itoh F
- Journal Title
  
  Digestion
  
  Volume: 84 Pages: 299-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590797
[Journal Article] Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer2011
- Author(s)
  Watanabe Y, Castro RJ, Kim HS, North B, Oikawa R, Hiraishi T, Ahmed SS, Chung W, Cho MY, Toyota M, Itoh F, Estecio MR, Shen L, Jelinek J, Issa JP
- Journal Title
  
  PLos One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590928
[Journal Article] SAFER ENDOSCOPIC GASTRIC MUCOSAL RESECTION : PREOPERATIVE PROTON PUMP INHIBITOR ADMINISTRATION2006
- Author(s)
  WATANABE Y, ITOH F, et al.
- Journal Title
  
  J GASTROENTEROL HEPATOL 10
  
  Pages: 1675-1680
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390222
[Journal Article] MUTATIONAL ANALYSIS OF 6-CATENIN AND THE RAS-RAF SIGNALING PATHWAY IN EARLY FLAT-TYPE COLORECTAL TUMORS2006
- Author(s)
  MIKAMI M, ITOH F, et al.
- Journal Title
  
  EUR J CANCER 42
  
  Pages: 3065-3072
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390222
[Journal Article] ACTIVATION OF THE RIBOSOMAL PROTEIN L13 GENE IN HUMAN GASTROINTESTINAL CANCER2006
- Author(s)
  KOBAYASHI T, ITOH F, et al.
- Journal Title
  
  INT J MOL MED 18
  
  Pages: 161-170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390222
[Journal Article] A FULL GENOME SCAN FOR GASTRIC CANCER.2005
- Author(s)
  AOKI M, ITOH F, et al.
- Journal Title
  
  J MED GENET 42
  
  Pages: 83-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] A FULL GENOME SCAN FOR GASTRIC CANCER.2005
- Author(s)
  AOKIM, ITOH F, et al.
- Journal Title
  
  J MED GENET 42
  
  Pages: 83-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390222
[Journal Article] IDENTIFICATION OF A NEW AUTOANTIBODY IN PATIENTS WITH CHRONIC HEPATITIS.2004
- Author(s)
  FUKUDA Y, ITOH F, et al.
- Journal Title
  
  HUM IMMUNOL 65
  
  Pages: 1530-1538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] NAIKAGAKU.2003
- Author(s)
  ITOH F.
- Journal Title
  
  NAIKAGAKU
  
  Pages: 1064-1066
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] EPIGENETIC IN ACTIVATION OF CHFR AND SENSITIVITY TO MICROTUBULE INHIBITORS IN GASTRIC CANCER.2003
- Author(s)
  SATOH A, TOYOTA M, ITOH F, et al.
- Journal Title
  
  CANCER RES 63
  
  Pages: 8606-8613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] EPIGENETIC IN ACTIVATON OF CHFR IN HUMAN TUMORS.2003
- Author(s)
  TOYOTA M, SASAKI Y, ITOH F, et al.
- Journal Title
  
  PROC NATL ACAD SCI USA 100
  
  Pages: 7818-7823
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] ASSOCIATION OF TRYPSIN EXPRESSION WITH TUMOR PROGRESSION AND MATRILYSIN EXPRESSION IN HUMAN COLORECTAL CANCER.2003
- Author(s)
  YAMAMOTO H, IKU S, ITOH F, et al.
- Journal Title
  
  J PATHOL 199
  
  Pages: 176-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] PANCREATIC INVOLVEMENT IN CHRONIC VIRAL HEPATITIS.
- Author(s)
  KATAKURA Y, ITOH F, et al.
- Journal Title
  
  (IN PRESS)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590663
[Journal Article] Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer
- Author(s)
  Oishi Y, Watanabe Y, Yoshida Y, Sato Y, Hiraishi T, Oikawa R, Maehata T, Suzuki H, Toyota M, Niwa H, Suzuki M, Itoh F
- Journal Title
  
  Tumour Biol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] 早期胃がんESD症例におけるピロリ菌除菌前後の変異株含有率の変動2018
- Author(s)
  及川律子、渡邊嘉行、宮本秀一、佐藤義典、小野尚子、間部克裕、山本博幸、加藤元嗣、伊東文生
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-16K15435
[Presentation] Enrichment of Helicobacter pylori mutant strains after eradication therapy analyzed by gastric wash-based quantitative pyrosequencing.2018
- Author(s)
  Watanabe Y, Oikawa R, Yamamoto H, Itoh F.
- Organizer
  AACR Annual Meeting 2018
- Data Source
  KAKENHI-PROJECT-16K15435
[Presentation] Enrichment of Helicobacter pylori mutant strains after eradication therapy analyzed by gastric wash-based quantitative pyrosequencing and NGS.2018
- Author(s)
  Watanabe Y, Oikawa R, Yamamoto H, Itoh F.
- Organizer
  Digestive Disease Week 2018
- Data Source
  KAKENHI-PROJECT-16K15435
[Presentation] Epigenetic alteration at HBV integrants is associated with methylation at flanking human genome2017
- Author(s)
  渡邊嘉行、及川律子、山本博幸、伊東文生
- Organizer
  The 107th Annual Meeting of the American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04304
[Presentation] NGS解析を応用した宿主側及びHBV側要因からみた肝臓がん組み込み部位とメチル化異常の検討2017
- Author(s)
  渡邊嘉行、及川律子、山本博幸、四柳宏、伊東文生
- Organizer
  第114回日本内科学会総会・講演会
- Data Source
  KAKENHI-PROJECT-15H04304
[Presentation] ヒトとピロリ菌ゲノム解析に基づく“胃全体の情報を網羅した”次世代の胃癌バイオマーカーの開発と診断・治療・予防への応用2017
- Author(s)
  山本博幸、渡邊嘉行、及川律子、宮本秀一、佐藤義典、小野尚子、間部克裕、加藤元嗣、伊東文生
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K15435
[Presentation] 次世代シークエンサーによるB型肝炎ウイルスDNA全組み込み解析に基づく発癌機構解明2016
- Author(s)
  山本博幸、渡邊嘉行、及川律子、山本雅一、國土典宏、田中真二、有井滋樹、四柳宏、小池和彦、伊東文生
- Organizer
  第53回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-15H04304
[Presentation] A Next-Generation Sequencing-based G-NaVI Method Revealed that DNA Methylation in the Integrated HBV Genome is Related to the Methylation Status of the Integration Sites within the Human Genome2016
- Author(s)
  山本博幸、渡邊嘉行、及川律子、渡邊綱正、四柳宏、伊東文生
- Organizer
  DDW2016
- Place of Presentation
  San Diego (U.S.A.)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04304
[Presentation] G-NAVI 法による宿主側及びHBV 側要因からみた組み込み部位とメチル化異常の検討2016
- Author(s)
  渡邊嘉行、及川律子、山本博幸、四柳宏、伊東文生
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15H04304
[Presentation] COX-2メチル化とHP感染2012
- Author(s)
  安田宏、渡邊嘉行、伊東文生
- Organizer
  第８回日本消化管学会
- Place of Presentation
  仙台（仙台国際センター）
- Data Source
  KAKENHI-PROJECT-23590928
[Presentation] COX-2メチル化とHP感染2012
- Author(s)
  安田宏, 渡邊嘉行, 伊東文生
- Organizer
  第8回日本消化管学会, 会長特別企画
- Place of Presentation
  仙台
- Year and Date
  2012-02-10
- Data Source
  KAKENHI-PROJECT-23590928
[Presentation]2011
- Author(s)
  安田宏, 渡邊嘉行, 伊東文生
- Organizer
  第17回日本ヘリコバクター学会
- Place of Presentation
  富山
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-23590928
[Presentation] Identification of DNA methylation changes in esophageal cancer before/after chemoradiation therapy using a MCA-microarray and bisulfate pyrosequencing2011
- Author(s)
  渡邊嘉行、伊東文生
- Organizer
  2010 A3フォーサイト事業ミーティング口演
- Place of Presentation
  札幌(ホテルニューオータニ札幌)
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] COX-2 hypermethylation in H. pylori-positive NSAID-induced gastric ulcer patients2011
- Author(s)
  Yasuda H, Watanabe Y, Itoh F
- Organizer
  AGA Research Forum
- Place of Presentation
  Chicago
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-23590928
[Presentation] 早期胃がんに対する新たな分子マーカーの臨床応用2011
- Author(s)
  伊東文生
- Organizer
  第31回日本分子腫瘍マーカー研究会
- Place of Presentation
  愛知(名古屋国際会議場)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] NSAID服用者に対する予防的除菌療法:COX-2 DNAメチル化からみたエビデンス2011
- Author(s)
  安田宏, 渡邊嘉行, 大石嘉恭, 佐藤義典, 前畑忠輝, 伊東文生
- Organizer
  第7回日本消化管学会ワークショップ
- Place of Presentation
  京都
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-23590928
[Presentation] マイクロアレイを用いた消化管がんの網羅的メチル化解析2011
- Author(s)
  渡邊嘉行, 伊東文生
- Organizer
  第62回日本電気泳動学会
- Place of Presentation
  神奈川(横浜市開港記念館)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] マイクロアレイを用いた消化管がんの網羅的メチル化解析2011
- Author(s)
  渡邊嘉行、伊東文生
- Organizer
  62th日本電気泳動学会総会シンポジウム1
- Place of Presentation
  横浜(横浜市開港記念会館)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] COX2 hypermethylation in HP-positive GU patients.2011
- Author(s)
  Yasuda H, Watanabe Y, Itoh F
- Organizer
  American Gastroenterological Association
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23590928
[Presentation] Identification of DNA methylation changes in esophageal cancer before/after chemoradiation therapy using a MCA-microarray and bisulfate.2010
- Author(s)
  Tsuda T, Watanabe Y, Itoh F
- Organizer
  ASCO2010 Chicago IL米国癌学会2010
- Place of Presentation
  シカゴイリノイ州米国
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] Identification of DNA methylation changes in esophageal cancer before/after chemoradiation therapy using a MCA-microarray and bisulfate pyrosequenci2010
- Author(s)
  津田享志、渡邊嘉行、伊東文生
- Organizer
  ASCO2010ポスター
- Place of Presentation
  Chicago
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21590797
[Presentation] 胃洗浄液を用いたメチル化解析の胃癌診断への応用2009
- Author(s)
  伊東文生
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21590797

1. Yamamoto Hiroyuki (40332910)

# of Collaborated Projects: 15 results

# of Collaborated Products: 13 results
2. IMAI Kohzoh (60117603)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. HINODA Yuji (10165128)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. YOSHIDA Yukinari (60311411)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. Maehata Tadateru (90534199)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
6. 渡邊嘉行 (90329243)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. ENDO Takao (40191928)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. ARIMURA Yoshiaki (80305218)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SASAZUKI Tekehiko (50014121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YOKOTA Jun (10191503)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. YASUDA Hiroshi (80262129)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
12. 谷内昭 (50045324)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 松野正紀 (80004737)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 磨伊正義 (80092807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 三輪晃一 (80019968)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. Okuse Chiaki (00318940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TANDA Mariko (40240931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAISHIRO Yasuyoshi (80347161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. INOKO Hidetoshi (10101932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAMAMOTO Ken (60274528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SASAKI Shigeru (10305229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TOYOTA Minoru (70270676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 高橋徹 (70253995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 安達正晃 (70240926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 牧口祐介 (40274922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 時野隆至 (40202197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 佐々木泰史 (70322328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 源利成 (50239323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 松尾康正 (70724756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 渡邊綱正 (20338528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 矢作直久 (90292937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 垣内英樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. NOSHO Katsuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 篠村恭久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ITOH Fumio 伊東 文生

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ウイルスゲノム組み込みと生体機能情報のリアルタイム血中可視化による子宮頸癌の制御Principal Investigator

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ウイルスゲノム組み込みと生体機能情報のリアルタイム血中可視化による革新的肝癌制御Principal Investigator

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Suppression of hepatocarcinogeneis based on the elucidation of HBV integration and epigenome alterations analyzed by G-NaVIPrincipal Investigator

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Identification of DNA methylation changes in esophageal cancer before/after chemoradiation therapy using an MCA-microarray and bisulfate pyrosequencingPrincipal Investigator

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膵癌スクリーニングを目的とした糞便中メチル化診断Principal Investigator

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膵癌治療の標的となる染色体不安定性機構起因分子の解明Principal Investigator

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ITOH Fumio 伊東文生