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Sugase Kenji  菅瀬 謙治

… Alternative Names

SUGASE Kenji  菅瀬 謙治

菅瀬 謙治  スガセ ケンジ

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Researcher Number 00300822
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-8623-7743
Affiliation (Current) 2025: 京都大学, 農学研究科, 教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 京都大学, 農学研究科, 教授
2016 – 2021: 京都大学, 工学研究科, 准教授
2015: 京都大学, 工学(系)研究科(研究院), 准教授
2013 – 2014: 公益財団法人サントリー生命科学財団, その他部局等, 主席研究員
2013: 公益財団法人 サントリー生命科学財団 生物有機科学研究所, 主席研究員 … More
2013: 公益財団法人サントリー生命科学財団, その他部局等, 研究員
2013: 公財)サントリー生命科学財団
2010 – 2012: 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 主席研究員
2011: (財)サントリー生物有機科学研究所, 主席研究員
2011: 公益法人サントリー生命科学財団, 生物有機科学研究所, 主席研究員
2009: Suntory Institute for Bioorganic Research, 主席研究員
2009: サントリー生物有機科学研究所, 主任研究員
2004: サントリー生物研, 研究員
2003: 財団法人サントリー生物有機科学研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 43040:Biophysics-related / Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Structural biochemistry / Complex systems / Medium-sized Section 13:Condensed matter physics and related fields / Biomolecular chemistry and related fields / Biophysics / Science and Engineering / Living organism molecular science … More
Except Principal Investigator
… More Structural biochemistry / Basic Section 32010:Fundamental physical chemistry-related / Transformative Research Areas, Section (III) / Living organism molecular science / Biological Sciences Less
Keywords
Principal Investigator
Rheo-NMR / NMR / タンパク質 / αシヌクレイン / アミロイド線維 / in-cell NMR / 蛋白質 / 剪断流 / ATP / アミロイド線維化 … More / 生物物理 / 動的構造 / 常磁性緩和法 / オリゴマー / Rheo-MD / 会合 / 膜なしオルガネラ / 非膜オルガネラ / eMD / 電場NMR / 液滴 / 分子動力学計算 / 凝集 / 電気泳動 / 電場 / 液-液相分離 / 溶液環境 / エピゲノム修飾 / 二本鎖DNA / 細胞内環境 / タンパク質‐薬剤相互作用 / 化学交換 / 19F-NMR / 解離定数 / 難水溶性薬剤 / タンパク質-薬剤相互作用 / 細胞抽出液 / 安定性 / 剪断力 / 夾雑環境 / 安定化/不安定化 / 細胞内夾雑環境 / 線維化 / タンパク質凝集 / 乱流 / off-center Couette cell / 速度イメージング / 流体 / レオロジー / 高分子構造・物性 / リン酸化ユビキチン / PINK1 / ユビキチン / Parkin / 分子認識 / 大量発現系 / リフォールディング / parkin / 高速NMR法 / 高速測定 / 揺らぎ / 分子認識および相互作用 / 分子認識及び相互作用 / 揺らぎの検出 / マイクロカロリメトリー / リン脂質膜 / グレリン … More
Except Principal Investigator
NMR / モンテカルロ法 / 分子シミュレーション / 超分子ゲル / 酸化還元 / シミュレーション / 相分離 / 分子凝集 / 3D-RISM / アミロイド線維化 / 液-液相分離 / 動的溶液環境 / 非膜型オルガネラ / アミロイド線維 / 液液相分離 / 天然変性タンパク質 / 蛋白質構造 / 立体構造解析 / NDSB / 構造多型 / 効率化 / 収率 / 精製 / 抗体 / 変性 / 凝集 / 溶解度 / 分子サイズ / オスモライト / 運動性 / メカニズム / スルホベタイン / 安定化 / 凝集防止 / タンパク質 / 標識体 / 鉄輸送 / 光親和標識体 / オオムギ / イネ科食物 / 基質選択性 / ムギネ酸鉄錯体トランスポーター / ファイトシデロフォア / トランスポーター / イネ科植物 / 鉄錯体 / ムギネ酸 / 生子 / 蛋白 / NMR / 天然変性 / 質量分析 / 生体分子 / 蛋白質 Less
  • Research Projects

    (21 results)
  • Research Products

    (146 results)
  • Co-Researchers

    (22 People)
  •  Rheo-NMR and paramagnetic relaxation-based structural determination of alpha-synuclein oligomersPrincipal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kyoto University
  •  Investigation of molecular aggregation control mechanism by solution environment and creation of molecular design tools

    • Principal Investigator
      吉田 紀生
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 32010:Fundamental physical chemistry-related
    • Research Institution
      Nagoya University
  •  Development of analytical platform for proteins in electric field and its applicationPrincipal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Kyoto University
  •  Advancement of Dynamic Solution Science

    • Principal Investigator
      Sekiyama Naotaka
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kyoto University
  •  Atomic-level analysis of proteins responding to dynamic solution environments using NMRPrincipal Investigator

    • Principal Investigator
      Sugase Kenji
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kyoto University
  •  Elucidation of the mechanism of protein aggregation in flow by using Rheo-NMR and Rheo-MDPrincipal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Kyoto University
  •  NMR study on local structural fluctuations of double-stranded DNAPrincipal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kyoto University
  •  Elucidation of the mechanism of amyloid fibrillation of alpha-synuclein starting from liquid-liquid phase separationPrincipal Investigator

    • Principal Investigator
      Sugase Kenji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kyoto University
  •  Development of a new methodology for determining dissociation constants of proteins and drugs in cellsPrincipal Investigator

    • Principal Investigator
      Sugase Kenji
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Kyoto University
  •  Velocity imaging of turbulence flow using Rheo-NMRPrincipal Investigator

    • Principal Investigator
      Sugase Kenji
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 13:Condensed matter physics and related fields
    • Research Institution
      Kyoto University
  •  Analysis of the effects of crowded environment and shear force to proteins using Rheo-NMRPrincipal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Kyoto University
  •  Elucidation of the mechanism of amyloid fibrillation using Rheo-NMR and development of a new Rheo-NMR instrumentPrincipal Investigator

    • Principal Investigator
      Sugase Kenji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Biomolecular chemistry and related fields
    • Research Institution
      Kyoto University
  •  Activation mechanism of ubiquitin ligase parkin by PINK1 and phosphorylated ubiquitinPrincipal Investigator

    • Principal Investigator
      Sugase Kenji
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University
  •  Ultra-fast NMR measurement to analyze dynamics of Sox2 in cellsPrincipal Investigator

    • Principal Investigator
      SUGASE Kenji
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biophysics
    • Research Institution
      Suntory Foundation for Life Sciences
  •  Elucidating a DNA recognition mechanism of a transcriptional factor protein by characterizing dynamic processes of specific/non-specific DNA-bound complexes

    • Principal Investigator
      HARADA ERISA
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Suntory Foundation for Life Sciences
  •  NMR緩和分散法によるiPS細胞誘導因子Oct3/4の揺らぎの検出Principal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Suntory Institute for Bioorganic Research
  •  Characterization of structural dynamics of intrinsically disordered proteins

    • Principal Investigator
      AKASHI Satoko
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Iron acquisition mechanism of graminaceous plants by mugineic acids

    • Principal Investigator
      MURATA Yoshiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Suntory Institute for Bioorganic Research
  •  Mechanism analysis of sulfobetaines' activity to prevent protein aggregation and application of sulfobetaines to unstable proteins

    • Principal Investigator
      WAKAMATSU Kaori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Gunma University
  •  Elucidation of dynamics and function of an iPS cell reprogramming factor Sox2 from the view point of an intrinsically disordered proteinPrincipal Investigator

    • Principal Investigator
      SUGASE Kenji
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      公益財団法人サントリー生命科学財団
      Suntory Institute for Bioorganic Research
  •  膜との相互作用によるグレリンの生理活性の調節機構Principal Investigator

    • Principal Investigator
      菅瀬 謙治
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Suntory Institute for Bioorganic Research

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

  • [Book] NMRによる有機材料分析と その試料前処理、データ解釈2021

    • Author(s)
      森本大智、菅瀬謙治
    • Total Pages
      676
    • Publisher
      技術情報協会
    • ISBN
      9784861048609
    • Data Source
      KAKENHI-PROJECT-18KK0075
  • [Book] Experimental Approaches of NMR Spectroscopy2018

    • Author(s)
      Walinda E, Sugase K
    • Total Pages
      636
    • Publisher
      Springer
    • ISBN
      9789811059650
    • Data Source
      KAKENHI-PROJECT-15H04342
  • [Book] Water and Biomolecules : Physical Chemistry of Life Phenomena (Biological and Medical Physics, Biomedical Engineering)2009

    • Author(s)
      Wright, P.E., Felitsky, D.J., Sugase, K., Dyson, H.J.
    • Total Pages
      307
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Book] Water and Biomolecules : Physical Chemistry of Life Phenomena(Biological and Medical Physics, Biomedical Engineering)(ed.Kuwajima K, Goto Y, Hirata F, Terazima M, Kataoka M)2009

    • Author(s)
      Wright PE, Felitsky DJ, Sugase K, Dyson HJ
    • Total Pages
      307
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Book] Water and Biomolecules : Physical Chemistry of Life Phenomena (Biological and Medical Physics, Biomedical Engineering) (ed. Kuwajima K, Goto Y, Hirata F, Terazima M, Kataoka M)2009

    • Author(s)
      Wright PE, Felitsky DJ, Sugase K, Dyson HJ
    • Total Pages
      307
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Book] Water and Biomolecules : Physical Chemistry of Life Phenomena(Biological and Medical Physics, Biomedical Engineering)(ed.Kuwajima K, Goto Y, Hirata F, Terazima M, Kataoka M)2009

    • Author(s)
      Wright PE, Felitsky DJ, Sugase K, Dyson HJ
    • Total Pages
      307
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Journal Article] Backbone resonance assignments of the CPEB3 [101?200] and CPEB3 [294?410]2025

    • Author(s)
      Saito Harunobu、Lee Yujin、Ueno Tomoharu、Sekiyama Naotaka、So Masatomo、Furukawa Ayako、Sugase Kenji
    • Journal Title

      Biomolecular NMR Assignments

      Volume: - Issue: 1 Pages: 109-114

    • DOI

      10.1007/s12104-025-10226-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22H05088
  • [Journal Article] Conformational Fluctuations and Induced Orientation of a Protein, Its Solvation Shell, and Bulk Water in Weak Non-Unfolding External Electric Fields2023

    • Author(s)
      Shuto Yusuke、Walinda Erik、Morimoto Daichi、Sugase Kenji
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 127 Issue: 34 Pages: 7417-7430

    • DOI

      10.1021/acs.jpcb.3c01683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22KK0098, KAKENHI-PROJECT-22K06161, KAKENHI-PROJECT-22K06168, KAKENHI-PLANNED-22H05088, KAKENHI-PROJECT-21H02442
  • [Journal Article] Rheo‐NMR Spectroscopy for Cryogenic‐Probe‐Equipped NMR Instruments to Monitor Protein Aggregation2022

    • Author(s)
      Morimoto Daichi、Walinda Erik、Yamamoto Akihiko、Scheler Ulrich、Sugase Kenji
    • Journal Title

      Current Protocols

      Volume: 2 Issue: 12

    • DOI

      10.1002/cpz1.617

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06161, KAKENHI-PLANNED-22H05088, KAKENHI-PROJECT-21H02442, KAKENHI-PROJECT-20K15756, KAKENHI-PROJECT-22K06168, KAKENHI-PROJECT-20K15757
  • [Journal Article] Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 β-Barrel2021

    • Author(s)
      Iwakawa Naoto、Morimoto Daichi、Walinda Erik、Leeb Sarah、Shirakawa Masahiro、Danielsson Jens、Sugase Kenji
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 125 Issue: 10 Pages: 2521-2532

    • DOI

      10.1021/acs.jpcb.0c11162

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-18J22192, KAKENHI-PROJECT-18K19297, KAKENHI-PROJECT-18K14665
  • [Journal Article] Expression, solubility monitoring, and purification of the co-folded LUBAC LTM domain by structure-guided tandem folding in autoinducing cultures2021

    • Author(s)
      Walinda Erik、Morimoto Daichi、Sorada Tomoki、Iwai Kazuhiro、Sugase Kenji
    • Journal Title

      Protein Expression and Purification

      Volume: 187 Pages: 105953-105953

    • DOI

      10.1016/j.pep.2021.105953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0075, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
  • [Journal Article] Multiple-State Monitoring of SOD1 Amyloid Formation at Single-Residue Resolution by Rheo-NMR Spectroscopy2021

    • Author(s)
      Iwakawa Naoto、Morimoto Daichi、Walinda Erik、Shirakawa Masahiro、Sugase Kenji
    • Journal Title

      Journal of the American Chemical Society

      Volume: 143 Issue: 28 Pages: 10604-10613

    • DOI

      10.1021/jacs.1c02974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-20H00453, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
  • [Journal Article] Effects of Weak Nonspecific Interactions with ATP on Proteins2021

    • Author(s)
      Nishizawa Mayu、Walinda Erik、Morimoto Daichi、Kohn Benjamin、Scheler Ulrich、Shirakawa Masahiro、Sugase Kenji
    • Journal Title

      Journal of the American Chemical Society

      Volume: 143 Issue: 31 Pages: 11982-11993

    • DOI

      10.1021/jacs.0c13118

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-20H00453, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
  • [Journal Article] Rigorous analysis of the interaction between proteins and low water-solubility drugs by qNMR-aided NMR titration experiments2021

    • Author(s)
      Hirakawa Takuya、Walinda Erik、Morimoto Daichi、Sugase Kenji
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 23 Issue: 38 Pages: 21484-21488

    • DOI

      10.1039/d1cp03175a

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21391, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
  • [Journal Article] Molecular recognition and deubiquitination of cyclic K48-linked ubiquitin chains by OTUB12021

    • Author(s)
      Sorada Tomoki、Morimoto Daichi、Walinda Erik、Sugase Kenji
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 562 Pages: 94-99

    • DOI

      10.1016/j.bbrc.2021.05.031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0075
  • [Journal Article] Backbone resonance assignments of the A2 domain of mouse von Willebrand factor2021

    • Author(s)
      Morimoto Daichi、Osugi Masanori、Mahana Yutaka、Walinda Erik、Shirakawa Masahiro、Sugase Kenji
    • Journal Title

      Biomolecular NMR Assignments

      Volume: 15 Issue: 2 Pages: 427-431

    • DOI

      10.1007/s12104-021-10041-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0075, KAKENHI-PROJECT-20H00453, KAKENHI-PROJECT-20K15757, KAKENHI-PROJECT-20K15756
  • [Journal Article] Pinpoint analysis of a protein in slow exchange using F1F2-selective ZZ-exchange spectroscopy: assignment and kinetic analysis.2020

    • Author(s)
      Mayu Nishizawa, Erik Walinda, Daichi Morimoto, Kenji Sugase
    • Journal Title

      Journal of Biomolecular NMR

      Volume: 0 Issue: 4-5 Pages: 0-0

    • DOI

      10.1007/s10858-020-00309-x

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14665, KAKENHI-PUBLICLY-18H04551, KAKENHI-PROJECT-19J13259
  • [Journal Article] Visualizing protein motion in Couette flow by all-atom molecular dynamics2020

    • Author(s)
      Walinda Erik、Morimoto Daichi、Shirakawa Masahiro、Scheler Ulrich、Sugase Kenji
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1864 Issue: 2 Pages: 129383-129383

    • DOI

      10.1016/j.bbagen.2019.06.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19297, KAKENHI-PROJECT-18KK0075, KAKENHI-PUBLICLY-18H04551, KAKENHI-WRAPUP-19H05452, KAKENHI-PROJECT-17K19196, KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-18K14665
  • [Journal Article] 高感度Rheo-NMRによるアミロイド線維化過程のその場観察2019

    • Author(s)
      森本 大智、菅瀬 謙治
    • Journal Title

      月刊「細胞」

      Volume: 685 Pages: 32-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0075
  • [Journal Article] 生体分子レオロジーNMRの開発と応用2019

    • Author(s)
      森本 大智、菅瀬 謙治
    • Journal Title

      日本核磁気共鳴学会機関誌

      Volume: 10 Pages: 64-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0075
  • [Journal Article] 高感度Rheo-NMRによるアミロイド線維化過程のその場観察2019

    • Author(s)
      森本 大智、菅瀬 謙治
    • Journal Title

      月刊「細胞」

      Volume: 51 Pages: 32-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Journal Article] 高感度Rheo-NMRによるアミロイド線維化過程のその場観察2019

    • Author(s)
      森本 大智、菅瀬 謙治
    • Journal Title

      月刊「細胞」

      Volume: 51 Pages: 32-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04551
  • [Journal Article] 生体分子レオロジーNMRの開発と応用2019

    • Author(s)
      森本 大智、菅瀬 謙治
    • Journal Title

      日本核磁気共鳴学会機関誌

      Volume: 10 Pages: 64-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04551
  • [Journal Article] 生体分子レオロジーNMRの開発と応用2019

    • Author(s)
      森本 大智、菅瀬 謙治
    • Journal Title

      日本核磁気共鳴学会機関誌

      Volume: 10 Pages: 64-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Journal Article] Overview of Relaxation Dispersion NMR Spectroscopy to Study Protein Dynamics and Protein-Ligand Interactions2018

    • Author(s)
      Walinda Erik、Morimoto Daichi、Sugase Kenji
    • Journal Title

      Current Protocols in Protein Science

      Volume: 92 Issue: 1

    • DOI

      10.1002/cpps.57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-15H04342, KAKENHI-PUBLICLY-18H04551
  • [Journal Article] Resolving biomolecular motion and interactions by R2 and R1ρ relaxation dispersion NMR2018

    • Author(s)
      Walinda Erik、Morimoto Daichi、Sugase Kenji
    • Journal Title

      Methods

      Volume: 148 Pages: 28-38

    • DOI

      10.1016/j.ymeth.2018.04.026

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-18K14665, KAKENHI-PUBLICLY-18H04551, KAKENHI-PROJECT-15H04342
  • [Journal Article] High-sensitivity Rheo-NMR spectroscopy for protein studies.2017

    • Author(s)
      Morimoto D., Walinda E., Iwakawa N., Nishizawa M., Kawata Y., Yamamoto A., Shirakawa M., Scheler U., Sugase K.
    • Journal Title

      Anal. Chem.

      Volume: 89 Issue: 14 Pages: 7286-7290

    • DOI

      10.1021/acs.analchem.7b01816

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19196, KAKENHI-PROJECT-16K18503
  • [Journal Article] F1F2-selective NMR spectroscopy2017

    • Author(s)
      Walinda Erik、Morimoto Daichi、Shirakawa Masahiro、Sugase Kenji
    • Journal Title

      Journal of Biomolecular NMR

      Volume: 68 Issue: 1 Pages: 41-52

    • DOI

      10.1007/s10858-017-0113-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18503, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-15H04342
  • [Journal Article] Real-time observation of the interaction between thioflavin T and an amyloid protein by using high-sensitivity Rheo-NMR.2017

    • Author(s)
      Iwakawa N., Morimoto D., Walinda E., Kawata Y., Shirakawa M., Sugase K.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 18 Issue: 11 Pages: 2271-2271

    • DOI

      10.3390/ijms18112271

    • NAID

      120006501319

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19196, KAKENHI-PROJECT-16K18503, KAKENHI-PLANNED-26119004
  • [Journal Article] Practical considerations for investigation of protein conformational dynamics by 15N R 1ρ relaxation dispersion.2017

    • Author(s)
      Walinda E, Morimoto D, Shirakawa M, Sugase K.
    • Journal Title

      Biomol NMR.

      Volume: 印刷中 Issue: 3 Pages: 201-209

    • DOI

      10.1007/s10858-017-0097-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-15H04342, KAKENHI-PROJECT-16K18503
  • [Journal Article] Efficient identification and analysis of chemical exchange in biomolecules by R1rho relaxation dispersion with Amaterasu2016

    • Author(s)
      Walinda, E. Morimoto, D. Nishizawa, M. Shirakawa, M. Sugase, K.
    • Journal Title

      Bioinformatics

      Volume: 32 Issue: 16 Pages: 2539-2541

    • DOI

      10.1093/bioinformatics/btw188

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04342, KAKENHI-PROJECT-16K18503
  • [Journal Article] Dual Function of Phosphoubiquitin in E3 Activation of Parkin2016

    • Author(s)
      Walinda, E. Morimoto, D. Sugase, K. Shirakawa, M.
    • Journal Title

      J Biol Chem

      Volume: 291 Issue: 32 Pages: 16879-16891

    • DOI

      10.1074/jbc.m116.728600

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04342, KAKENHI-PROJECT-16K18503
  • [Journal Article] Quantitative analysis of protein–ligand interactions by NMR.2016

    • Author(s)
      4.A. Furukawa, T. Konuma, S. Yanaka, K. Sugase
    • Journal Title

      Prog. Nucl. Magn. Reson. Sp.

      Volume: 96 Pages: 47-57

    • DOI

      10.1016/j.pnmrs.2016.02.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04342
  • [Journal Article] Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy2014

    • Author(s)
      Furukawa, A., Sugase, K., Morishita, R., Nagata, T., Kodaki, T., Takaori-Kondo, A., Ryo, A., Katahira, M.
    • Journal Title

      Angew. Chem. Int. Ed. Engl.

      Volume: 53 Issue: 9 Pages: 2349-2352

    • DOI

      10.1002/anie.201309940

    • NAID

      120005647511

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23570146, KAKENHI-PUBLICLY-24113710, KAKENHI-PUBLICLY-24121714, KAKENHI-PROJECT-24390115, KAKENHI-PUBLICLY-25115507, KAKENHI-PROJECT-25650056, KAKENHI-PUBLICLY-26104520, KAKENHI-PROJECT-26840040
  • [Journal Article] Solution Structure of the Ubiquitin-associated (UBA) Domain of Human Autophagy Receptor NBR1 and its Interaction with Ubiquitin and Polyubiquitin.2014

    • Author(s)
      E. Walinda, D. Morimoto. K. Sugase. T. Konuma. H. Tochio, M. Shirakawa
    • Journal Title

      The Journal of Biological Chemistry

      Volume: (印刷中) Issue: 20 Pages: 13890-13902

    • DOI

      10.1074/jbc.m114.555441

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J06373, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-25112514, KAKENHI-PLANNED-26119004
  • [Journal Article] Solid-state NMR spectra of lipid- anchored proteins under magic angle spinning2014

    • Author(s)
      Nomura, K., Harada, E., Sugase, K., Shimamoto, K.
    • Journal Title

      J. Phys. Chem. B.

      Volume: 118 Pages: 2405-2413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Journal Article] Solid-state NMR spectra of lipid-anchored proteins under magic angle spinning.2014

    • Author(s)
      Nomura, K., Harada, E., Sugase, K., Shimamoto, K.
    • Journal Title

      J. Phys. Chem. B.

      Volume: 118 Issue: 9 Pages: 2405-2413

    • DOI

      10.1021/jp4124106

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25410187, KAKENHI-PROJECT-25650056
  • [Journal Article] Solution structure of the Q41N variant of ubiquitin as a model for the alternatively folded N2 state of ubiquitin2013

    • Author(s)
      Soichiro Kitazawa, Tomoshi Kameda, Maho Yagi-Utsumi, Kenji Sugase, Nicola J. Baxter, Koichi Kato, Michael P. Williamson, Ryo Kitahara.
    • Journal Title

      Biochemistry

      Volume: 52 Issue: 11 Pages: 1874-1885

    • DOI

      10.1021/bi301420m

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23870043, KAKENHI-PROJECT-25650056, KAKENHI-PLANNED-20107004, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-23107729
  • [Journal Article] Fast and accurate fitting of relaxation dispersion data using the flexible software package GLOVE2013

    • Author(s)
      Sugase, K., Konuma, T., Lansing, J.C., Wright, P.E.
    • Journal Title

      J. Biomol. NMR

      Volume: 56 Issue: 3 Pages: 275-283

    • DOI

      10.1007/s10858-013-9747-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-25650056, KAKENHI-PROJECT-25840059
  • [Journal Article] The monomer-seed interaction mechanism in the formation of the β2-microglobulin amyloid fibril clarified by solution NMR techniques.2012

    • Author(s)
      Yanagi K
    • Journal Title

      J. Mol. Biol.

      Volume: 422 Issue: 3 Pages: 390-402

    • DOI

      10.1016/j.jmb.2012.05.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075, KAKENHI-PROJECT-24370067, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-23107719
  • [Journal Article] 実践relaxation dispersion法2012

    • Author(s)
      菅瀬謙治
    • Journal Title

      NMR

      Volume: 3 Pages: 82-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy2011

    • Author(s)
      Sugase, K.
    • Journal Title

      J. Biomol. NMR

      Volume: 50 Issue: 3 Pages: 219-227

    • DOI

      10.1007/s10858-011-9511-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Journal Article] Boosting protein dynamics studies using quantitative nonuniform sampling NMR spectroscopy2011

    • Author(s)
      Matsuki Y, Konuma T, Fujiwara T, Sugase K
    • Journal Title

      J.Phys.Chem.B

      Volume: 115 Issue: 46 Pages: 13740-13745

    • DOI

      10.1021/jp2081116

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Journal Article] Calcitonin in a protochordate, Ciona intestinalis―the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily2009

    • Author(s)
      Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
    • Journal Title

      FEBS J. 276

      Pages: 4437-4447

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Journal Article] Calcitonin in a protochordate, Ciona intestinalis-the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily2009

    • Author(s)
      Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
    • Journal Title

      FEBS J. 276

      Pages: 4437-4447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Journal Article] Calcitonin in a protochordate, Ciona intestinalis--the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily.2009

    • Author(s)
      Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
    • Journal Title

      FEBS J. 276

      Pages: 4437-4447

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Journal Article] Calcitonin in a protochordate, Ciona intestinalis--the prototype of the vertebrate calcitonin/calcitonin gene-related peptide superfamily.2009

    • Author(s)
      Sekiguchi T, Suzuki N, Fujiwara N, Aoyama M, Kawada T, Sugase K, Murata Y, Sasayama Y, Ogasawara M, Satake H
    • Journal Title

      FEBS J. Vol.276

      Pages: 4437-4447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy

    • Author(s)
      Kenji Sugase
    • Journal Title

      Journal of Biomolecular NMR

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy

    • Author(s)
      Sugase K
    • Journal Title

      J.Biomol.NMR in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Journal Article] Elucidating slow binding kinetics of a protein without observable bound resonances by longitudinal relaxation NMR spectroscopy

    • Author(s)
      Kenji Sugase
    • Journal Title

      Journal of Biomolecular NMR

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Journal Article] Lipopolysaccharide induces raft domain expansion in membrane composed of a phospholipid-cholesterol-sphingomyelin ternary system.

    • Author(s)
      Nomura K, Maeda M, Sugase K, Kusumoto S
    • Journal Title

      Innate Immun. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Patent] 剪断流を発生させる器具2023

    • Inventor(s)
      菅瀬謙治、森本大智、山本昭彦、保科好秀
    • Industrial Property Rights Holder
      国立大学法人京都大学、エアープロ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-170462
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-18KK0075
  • [Patent] 剪断流を発生させる器具2023

    • Inventor(s)
      菅瀬謙治、森本大智、山本昭彦、保科好秀
    • Industrial Property Rights Holder
      菅瀬謙治、森本大智、山本昭彦、保科好秀
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-170462
    • Filing Date
      2023
    • Data Source
      KAKENHI-PLANNED-22H05088
  • [Patent] 剪断流を発生させる器具2019

    • Inventor(s)
      菅瀬謙治、森本大智、保科好秀
    • Industrial Property Rights Holder
      菅瀬謙治、森本大智、保科好秀
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-111013
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Patent] 剪断流を発生させる器具2019

    • Inventor(s)
      菅瀬謙治、森本大智、保科好秀
    • Industrial Property Rights Holder
      菅瀬謙治、森本大智、保科好秀
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-111013
    • Filing Date
      2019
    • Data Source
      KAKENHI-PUBLICLY-18H04551
  • [Presentation] 電場中におけるタンパク質の動的構造解析基盤の構築と凝集化機構解明への応用2024

    • Author(s)
      首藤佑輔、Walinda Erik、森本大智、菅瀬謙治
    • Organizer
      凝縮系の理論化学研究会
    • Invited
    • Data Source
      KAKENHI-PLANNED-22H05088
  • [Presentation] 期記憶形成に関わるCPEB3の自己凝集における相互作用部位の解明2024

    • Author(s)
      李勇進、齋藤元伸、上野元春、宗正智、古川亜矢子、菅瀬謙治
    • Organizer
      第47回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-22H05088
  • [Presentation] α-シヌクレインの凝集抑制をもたらすATPとの弱い相互作用の定量解析2024

    • Author(s)
      首藤祐輔、Benjamin Kohn、Erik Walinda、森本大智、Ulrich Scheler、宗正智、古川亜矢子、菅瀬謙治
    • Organizer
      第63回NMR討論会
    • Data Source
      KAKENHI-PLANNED-22H05088
  • [Presentation] 長期記憶関連タンパク質CPEB3のユビキチン化による凝集機構解析2024

    • Author(s)
      齋藤元伸、上野元春、森本大智、関山直孝、宗正智、古川亜矢子、菅瀬謙治
    • Organizer
      第47回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-22H05088
  • [Presentation] 電場中におけるタンパク質の動的構造解析基盤の構築と凝集化機構解明への応用2024

    • Author(s)
      首藤佑輔、Walinda Erik、森本大智、菅瀬謙治
    • Organizer
      凝集系の理論化学 研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22KK0098
  • [Presentation] 分子夾雑環境による免疫抑制剤結合タンパク質FKBP12の薬剤認識への影響のNMR動的構造解析2021

    • Author(s)
      平河 卓也、森本 大智、菅瀬 謙治、白川 昌宏
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-20K21391
  • [Presentation] Highly Accurate Analysis of the Interaction Between Proteins and Low Water-solubility Drugs by qNMR-aided NMR Titration Experiments2021

    • Author(s)
      Takuya Hirakawa, Daichi Morimoto, Kenji Sugase
    • Organizer
      ISMAR-APNMR2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21391
  • [Presentation] Elucidation of Fibrillation Mechanism of ALS-Related Protein SOD12019

    • Author(s)
      Kenji Sugase
    • Organizer
      IPR Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04551
  • [Presentation] In situ Monitoring of Amyloid Fibril Formation Processes Using Rheo-NMR2019

    • Author(s)
      Kenji Sugase, Daichi Morimoto, Walinda Erik, Naoto Iwakawa, Akihiko Yamamoto, Ulrich Scheler
    • Organizer
      8th APNMR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Presentation] In situ Monitoring of Amyloid Fibril Formation Processes Using Rheo-NMR2019

    • Author(s)
      Kenji Sugase
    • Organizer
      8th APNMR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0075
  • [Presentation] In situ Monitoring of Amyloid Fibril Formation Processes Using Rheo-NMR2019

    • Author(s)
      Kenji Sugase, Daichi Morimoto, Walinda Erik, Naoto Iwakawa, Akihiko Yamamoto, Ulrich Scheler
    • Organizer
      8th APNMR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04551
  • [Presentation] High-Sensitivity Rheo-NMR Spectroscopy for Protein Studies2018

    • Author(s)
      Kenji Sugase
    • Organizer
      EUROMAR 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Presentation] 高感度Rheo-NMRによるタンパク質線維化のその場解析2018

    • Author(s)
      菅瀬謙治
    • Organizer
      日本表面真空学会 2018年9月研究例会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Presentation] High-sensitivity Rheo-NMR spectroscopy for protein studies.2017

    • Author(s)
      Sugase K
    • Organizer
      JGP-Chem Kyoto-Bordeaux Faculty & Student Research Workshop on Chiral Nanostructures for Photonic Applications
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Presentation] High-sensitivity Rheo-NMR spectroscopy for protein studies.2017

    • Author(s)
      Sugase K
    • Organizer
      ISMAR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19196
  • [Presentation] Characterizing Conformational Flexibility of a DNA Binding Protein2014

    • Author(s)
      Erisa Harada, Tsuyoshi Konuma, Kenji Sugase
    • Organizer
      55th Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      アメリカ ボストン
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] HLA-HIV由来抗原ペプチド複合体-水のダイナミクスと抗原提示能2014

    • Author(s)
      菅瀬謙治
    • Organizer
      関西創薬化学コミュニティ
    • Place of Presentation
      新大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650056
  • [Presentation] Characterizing Conformational Flexibility of a DNA Binding Protein2014

    • Author(s)
      Erisa Harada, Tsuyoshi Konuma, Kenji Sugase
    • Organizer
      55th Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] Relaxation dispersion spectroscopy2013

    • Author(s)
      Sugase, K.
    • Organizer
      2013 Taiwan magnetic resonance society annual meeting
    • Place of Presentation
      Chiayi, Taiwan
    • Year and Date
      2013-01-29
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Extracting Information on Protein Dynamics from Crowded NMR Spectra Using Relaxation Dispersion Difference2013

    • Author(s)
      Tsuyoshi Konuma, Erisa Harada, Kenji Sugase
    • Organizer
      5th Asia-Pacific NMR Symposium
    • Place of Presentation
      the Brisbane Convention and Exhibition Centre, Brisbane, Australia
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Mechanism of coupled folding and binding of an intrinsically disordered protein2013

    • Author(s)
      Kenji Sugase
    • Organizer
      2013 Taiwan magnetic resonance society annual meeting
    • Place of Presentation
      Chiayi, Taiwan
    • Year and Date
      2013-01-29
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Analysis of protein dynamics in living human cells2013

    • Author(s)
      Kenji Sugase, Erisa Harada, Toshio Takahashi, Shoko Mori
    • Organizer
      第36回分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] Mechanism of the distal regulation of substrate binding through intrinsic fluctuation in an enzyme2013

    • Author(s)
      Kenji Sugase
    • Organizer
      The 10th Korea-Japan Bilateral Symposium on Biological NMR
    • Place of Presentation
      ソウル、韓国
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650056
  • [Presentation] Analysis of protein dynamics in living human cells2013

    • Author(s)
      Kenji Sugase
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25650056
  • [Presentation] 揺らぎが制御するヘム分解酵素反応の遠位効果2013

    • Author(s)
      菅瀬謙治
    • Organizer
      第14回若手NMR研究会
    • Place of Presentation
      京都トラベラーズ・イン、京都
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Mechanism of the distal regulation of substrate binding through intrinsic fluctuation in an enzyme2013

    • Author(s)
      Kenji Sugase
    • Organizer
      The 10^<th> Korea-Japan Bilaterial Symposium on Biological NMR
    • Place of Presentation
      Seuol, Korea
    • Year and Date
      2013-07-04
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] Extracting information on protein dynamics from crowded NMR spectra using relaxation dispersion difference2013

    • Author(s)
      Tsuyoshi Konuma, Erisa Harada, Kenji Sugase
    • Organizer
      5^<th> Asia-Pacific NMR Symposium
    • Place of Presentation
      Brisbane, Australia
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] Analysis of protein dynamics in living human cells2013

    • Author(s)
      Kenji Sugase, Erisa Harada, Toshio Takahashi, Shoko Mori
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド、神戸
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Mechanism of the distal regulation of substrate binding through intrinsic fluctuation in an enzyme2013

    • Author(s)
      Kenji Sugase
    • Organizer
      The 10th Korea-Japan Bilateral Symposium on Biological NMR
    • Place of Presentation
      Seoul National University, Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Analysis of protein dynamics in living human cells2013

    • Author(s)
      Kenji Sugase, Erisa Harada, Toshio Takahashi, Shoko Mori
    • Organizer
      第36回分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] 揺らぎが制御するヘム分解酵素反応の遠位効果2013

    • Author(s)
      菅瀬謙治
    • Organizer
      第14回若手NMR研究会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650056
  • [Presentation] Elucidation of nonspecific DNA-binding mechanism by quantitative analysis of chemical shift changes2013

    • Author(s)
      Tsuyoshi Konuma, Erisa Harada, Takashi Oda, Mamoru Sato, Kenji Sugase
    • Organizer
      5^<th> Asia-Pacific NMR Symposium
    • Place of Presentation
      Brisbane, Australia
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] 緩和分散差スペクトル法による混みあったNMRスペクトルの緩和分散データの解析2012

    • Author(s)
      小沼剛、菅瀬謙治
    • Organizer
      第51回 NMR討論会
    • Place of Presentation
      名古屋市
    • Year and Date
      2012-11-08
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Elucidation of the DNA-binding dynamics of the transcription factor Oct3/4 POU homeodomain2012

    • Author(s)
      Tsuyoshi Konuma, Erisa Harada, Kenji Sugase
    • Organizer
      25th International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Lyon, France
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] 揺らぎから機能をどのように見るか2012

    • Author(s)
      菅瀬謙治
    • Organizer
      よこはまNMR構造生物学研究会第43回ワークショップ
    • Place of Presentation
      理化学研究所横浜研究所交流棟ホール(神奈川)
    • Year and Date
      2012-02-06
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 揺らぎが制御するヘム分解酵素反応の遠位効果2012

    • Author(s)
      原田、杉島、原田、野口、福山、菅瀬
    • Organizer
      第35回 日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24770106
  • [Presentation] 動的構造解析による酵素ヘムオキシゲナーゼの機能発現メカニズムの解明2011

    • Author(s)
      菅瀬謙治
    • Organizer
      第17回創薬情報研究会
    • Place of Presentation
      新大阪丸ビル新館(大阪)
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Stabilization of proteins by choline-O-sulfate during preparation and NMR measurement2011

    • Author(s)
      Kaori Wakamatsu, Haimei Wang, Masahiko Takahashi, Kazuma Nakazawa, Mitsuhiko Yoshizawa, Tetsuro Demura, Kazuo Hosoda, Shin-ichi Terawaki, Nobukazu Nameki, Kenji Sugase
    • Organizer
      The International Symposium on Nuclear Magnetic Resonance 2011
    • Place of Presentation
      横浜大さん橋ホール
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] Boosting Protein Dynamics Studies using Quantitative Non-Uniform Sampling (NUS) NMR2011

    • Author(s)
      菅瀬謙治
    • Organizer
      第50回NMR討論会
    • Place of Presentation
      大さん橋ホール(神奈川)
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Stabilization of proteins by cholie-O-sulfate duing preparation and NMR measurement2011

    • Author(s)
      K. Wakamatsu, H. Wang, M. Takahashi, K. Nakazawa, M. Yoshizawa, T. Demura, K. Hosoda, S. Teraw, N. Nameki, K. Sugase
    • Organizer
      The International Symposium on Nuclear Magnetic Resonance 2011
    • Place of Presentation
      横浜大さん橋ホール(神奈川県)
    • Year and Date
      2011-11-15
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] NMRによるヘムオキシゲナーゼのヘム認識機構の解明2010

    • Author(s)
      菅瀬謙治
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学蛋白質研究所(大阪府)
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] 緩和分散解析用プログラムGLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 蛋白質・ペプチドの溶液NMRへのスルホベタイン類の応用2010

    • Author(s)
      若松馨, 王海梅, 五十嵐麗樹, 神谷歩, 高橋雅彦, 手塚福栄, 向瓏, 石井毅, 細田和男, 行木信一, 菅瀬謙治
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] オオムギのムギネ酸類・鉄錯体トランスポーターHvYS1における基質選択性に関与する膜外ループの解析2010

    • Author(s)
      村田佳子,原田英理砂、菅瀬謙治、岩下孝
    • Organizer
      第21回日本微量元素学会年会
    • Place of Presentation
      京都大学百周年時計台記念館(京都)
    • Data Source
      KAKENHI-PROJECT-21310148
  • [Presentation] NMRによるヘムオキシゲナーゼのヘム認識機構の解明2010

    • Author(s)
      菅瀬謙治
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学蛋白質研究所(大阪府)
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 緩和分散解析用プログラムGLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] 動きの面から見た核内タンパク質の機能2010

    • Author(s)
      菅瀬謙治
    • Organizer
      ターゲットタンパク研究プログラム第3回研究交流会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2010-03-04
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] 緩和分散解析用プログラムGLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      XXIVth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns convention centre (Australia)
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] NMRによる天然変性タンパク質の動的構造解析2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Fluctuation and function of nuclear proteins2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学(岩手県)
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] NMRによるヘムオキシゲナーゼのヘム認識機構の解明2010

    • Author(s)
      菅瀬謙治
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学蛋白質研究所(大阪府)
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] 動きの面から見た核内タンパク質の機能2010

    • Author(s)
      菅瀬謙治
    • Organizer
      ターゲットタンパク研究プログラム第3回研究交流会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2010-03-04
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] Fluctuation and function of nuclear proteins2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学(岩手県)
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] Fluctuation and function of nuclear proteins2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学、岩手
    • Year and Date
      2010-09-20
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Fluctuation and function of nuclear proteins2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      XXIVth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Effects of non-detergent sulfobetaines on protein dynamics2010

    • Author(s)
      Kaori Wakamatau, Haimei Wang, Ayaka Matsui, Nobukazu Nameki, Kenji Sugase
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      XXIVth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns convention centre (Australia)
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010

    • Author(s)
      Sugase, K., Lansing, J.C. Wright, P.E.
    • Organizer
      XXIVth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns convention centre, Australia
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] NMRによる天然変性タンパク質の動的構造解析2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] NMRによる天然変性タンパク質の動的構造解析2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] Effects of NDSB, amyloid formation inhibitor, on protein structure2010

    • Author(s)
      Haimei Wang, Mayu Enomoto, Nobukazu Nameki, Kenji Sugase, Kaori Wakamatsu
    • Organizer
      5th International peptide symposium
    • Place of Presentation
      京都国際会館
    • Year and Date
      2010-12-04
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] 動きの面から見た核内タンパク質の機能2010

    • Author(s)
      菅瀬謙治
    • Organizer
      ターゲットタンパク研究プログラム第3回研究交流会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-04
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Fitting Relaxation Dispersion Data With A New Software Package GLOVE2010

    • Author(s)
      菅瀬謙治
    • Organizer
      XXIVth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns convention centre (Australia)
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 蛋白質・ペプチドの溶液NMRへのスルホベタイン類の応用2010

    • Author(s)
      若松馨, 王海梅, 五十嵐麗樹, 神谷歩, 高橋雅彦, 手塚福栄, 向瓏, 石井毅, 細田和男, 行木信一, 菅瀬謙治
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      タワーホール船堀
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] 動きの面から見た核内タンパク質の機能2010

    • Author(s)
      菅瀬謙治
    • Organizer
      ターゲットタンパク研究プログラム第3回研究交流会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2010-03-04
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] NMR による天然変性タンパク質の動的構造解析2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Fluctuation and function of nuclear proteins2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学(岩手県)
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] NMR による天然変性タンパク質の動的構造解析2010

    • Author(s)
      菅瀬謙治
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター、北海道
    • Year and Date
      2010-06-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] オオムギのムギネ酸類3価鉄錯体トランスポーターHvYS1の基質特異性に関わる膜外ループの解析2009

    • Author(s)
      村田佳子,原田英理砂、菅瀬謙治、難波康祐、岩下孝
    • Organizer
      第4回トランスポーター研究会
    • Place of Presentation
      東京大学(東京)
    • Data Source
      KAKENHI-PROJECT-21310148
  • [Presentation] 天然変性タンパク質の構造と機能の最前線2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回 生命科学 夏の学校
    • Place of Presentation
      神戸セミナーハウス(三田)
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009

    • Author(s)
      菅瀬謙治
    • Organizer
      The 3rd APNMR Biannual Asia-Pacific NMR Symposium
    • Place of Presentation
      Ramada hotel (Jeju, Korea)
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 天然変性タンパク質の構造と機能の最前線2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回 生命科学 夏の学校
    • Place of Presentation
      神戸セミナーハウス(三田)
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009

    • Author(s)
      菅瀬謙治
    • Organizer
      The 3rd APNMR Biannual Asia-Pacific NMR Symposium
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] 天然変性状態と機能の相関2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 天然変性状態と機能の相関2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] 天然変性タンパク質の構造と機能の最前線2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回 生命科学 夏の学校
    • Place of Presentation
      神戸セミナーハウス(三田)
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PUBLICLY-21107531
  • [Presentation] Structural analysis of an outer membrane loop responsible for substrate specificity of Fe(III)-phytosiderophore transpoerters2009

    • Author(s)
      原田英理砂、村田佳子、菅瀬謙治
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-21310148
  • [Presentation] NDSB類が蛋白質のダイナミクスに及す効果2009

    • Author(s)
      若松馨, 王海梅, 松井文香, 神谷歩, 加藤瀬里, 行木信一, 菅瀬謙治
    • Organizer
      第48回NMR討論会
    • Place of Presentation
      九州大学
    • Year and Date
      2009-11-10
    • Data Source
      KAKENHI-PROJECT-21570108
  • [Presentation] 天然変性状態と機能の相関2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] Elucidation of protein-protein interactions by relaxation NMR spectroscopy2009

    • Author(s)
      Sugase, K
    • Organizer
      The 3rd APNMR Biannual Asia-Pacific NMR Symposium
    • Place of Presentation
      Ramada hotel, Korea
    • Year and Date
      2009-10-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-21113003
  • [Presentation] 天然変性タンパク質の構造と機能の最前線2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第49回生命科学夏の学校
    • Place of Presentation
      三田
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PROJECT-21770126
  • [Presentation] 天然変性状態と機能の相関2009

    • Author(s)
      菅瀬謙治
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PUBLICLY-21107531
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      村田佳子、難波康祐、馬建鋒、菅瀬謙治、堀川学、岩下孝、楠本正一
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      第51回天然有機化合物討論会
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      名古屋大学(名古屋)
    • Data Source
      KAKENHI-PROJECT-21310148
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      若松馨, 王海梅, 松井文香, 神谷歩, 加藤瀬里, 行木信一, 菅瀬謙治
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      第48回NMR討論会
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      九州大学(福岡県)
    • Year and Date
      2009-11-10
    • Data Source
      KAKENHI-PROJECT-21570108
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    • Organizer
      The 3rd APNMR Biannual Asia-Pacific NMR Symposium
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      Ramada hotel(Jeju, Korea)
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PUBLICLY-21107531
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    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Data Source
      KAKENHI-PROJECT-21310148
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    • Organizer
      The 3rd APNMR Biannual Asia-Pacific NMR Symposium
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      Ramada hotel(Jeju, Korea)
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-21770126
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    • Author(s)
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    • Organizer
      第48回NMR討論会
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      九州大学医学部百年講堂(福岡県)
    • Data Source
      KAKENHI-PLANNED-21113003
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    • Organizer
      ICMRBS XXVI
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    • Year and Date
      2014-08-24 – 2014-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650056
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