Mishima Kenichi 三島健一

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MISHIMA Kenichi 三島健一

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Researcher Number	00320309
Other IDs
Affiliation (Current)	2025: 福岡大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2022: 福岡大学, 薬学部, 教授 2014: 福岡大学, 薬学部臨床疾患薬理学, 准教授 2007 – 2013: Fukuoka University, Faculty of Pharmaceutical Sciences, Associate Professor 2009: 神岡大学, 薬学部, 准教授 2000 – 2006: 福岡大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Applied pharmacology / 応用薬理学・医療系薬学 Except Principal Investigator Psychiatric science / 応用薬理学・医療系薬学 / Basic Section 47060:Clinical pharmacy-related / Medical pharmacy / Neurochemistry/Neuropharmacology / Neurosurgery / Embryonic/Neonatal medicine / General pharmacology / Wood science / Applied pharmacology
Keywords	Principal Investigator 学習・記憶 / 脳虚血 / 新生児 / カンナビノイド / 2-AG / 大麻受容体 / learning and memory / corticosterone / hypoxia-ischemia / astrocyte … More / neonate / GDNF / 回転行動 / コルチコステロン / 低酸素・虚血脳症 / アストロサイト / 血栓 / TSP-1 / 脳梗塞 / ADMATS13 / Tsp-1 / t-PA / VWF / ADAMTS13 / 細胞治療 / 卵膜由来間葉系幹細胞 / 再生 / 性差 / 機能再生 / 緩徐進行性脳損傷 / 低酸素性虚血性脳症 / 多発性硬化症 / カタレプシー / アナンダミド / 2-アラキドノイルグリセロール / 攻撃行動 / カンナビノイド受容体 / THC … More Except Principal Investigator アルツハイマー病 / 脳梗塞 / 大麻 / β-アミロイド / バイオマーカー / 脳虚血 / Δ9-tetrahydrocannabinol / アポトーシス / 迷路学習 / 動物モデル / 脳循環障害 / 糖尿病 / ガングリオシド / マイクロドメイン / schizophrenia / autism / vasopressin / social interaction / CB1 cannabinoid receptor / Δ^9-Tetrahvdrocannabinol / Δ9-tetrahydrocannabinol(THC) / THC / 自閉症 / 統合失調症 / 社会的行動 / バソプレシン / 脳神経疾患 / 脳・神経 / life-style related disease / microdomain / amyloid / insulin resistance / cerebrovascular disease / Alzheimer's disease / インスリン抵抗性糖尿病 / Sensorimotor gating / Pubertal / Psychosis / Prepulse inhibition / CB_1 cannabinoid receptor / Δ^9-Tetrahydrocannabinol / 若年期、思春期 / prepulse inhibition (PPI) / Δ9-tetrahydrocannabinol (THC) / 情報処理障害 / 若年期,思春期 / prepulse inhibition / 精神障害 / diabetes / Spinal cord / allodynia / Muscarinic receptors / Neuropathetic pain / Morphine / 痛覚 / clonidine / 神経因性疼痛 / バソプレシン受容体 / α2受容体 / アロディニア / 脊髄 / ムスカリン受容体 / 糖尿病性疼痛 / モルヒネ / MEMORY / MAZE PERFORMANCE / RAT / ChE-inhibitor / CEREBRAL ISCHEMIA / ALZHEIMER'S DISEASE / 空間認知記憶 / ChE-阻害剤 / 記憶 / ラット / コリンエステラーゼ阻害剤 / 遅発性脳虚血 / MRI / VWF / 炎症 / 血栓 / 脳動脈瘤 / クモ膜下出血 / ADAMTS13 / 脳傷害 / 低酸素性虚血 / 虚血 / 脳障害 / 新生児 / CD34陽性細胞 / 中大脳動脈閉塞 / 臍帯血幹細部 / 脳血流 / マウス / 細胞治療 / 幹細胞 / 臍帯血 / 新生児低酸素性虚血性脳症 / 新生児脳症 / 新生児脳梗塞 / ストレス / 超音波発声 / カンナビノイド / アルツハマー病 / Telmisartan / HMGB1 / TNFα / 炎症性サイトカイン / PPARγ / 熱分解 / 加水分解 / オリゴ糖 / 亜臨界水 / 多糖類 / β-1,3グルカン / タンニン / ベルベリン / グリチルリチン酸 / 食用キノコ / ブクリョウ / 抗腫瘍活性 / マキネッタ抽出法 / βグルカン / 危険因子 / 薬理学 / インスリン抵抗性 / アミロイドβ / インスリン受容体 Less

Utilities of plasma protein as a biomarker for the progression of cerebral infarction
- Principal Investigator
  
  Irie Keiichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
Utilities of leucine rich alpha-2 glycoprotein as a biomarker for the progression of cerebral infarction
- Principal Investigator
  
  Irie Keiichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fukuoka University
The effect of meal content on emotional behavior: role of cannabinoid receptorPrincipal Investigator
- Principal Investigator
  
  Kenichi Mishima
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
Neuroprotective effects of ADAMTS13 against delayed brain ischemia after subarachnoid hemorrhage
- Principal Investigator
  
  Fujioka Masayuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Nara Medical University
Umbilical cord blood cell therapies in a novel neonatal stroke model
- Principal Investigator
  
  TSUJI MASAHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  National Cardiovascular Center Research Institute
A possible neuroprotective role of ADAMTS13 by ameliorating post-ischemic hypoperfusionPrincipal Investigator
- Principal Investigator
  
  MISHIMA Kenichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
環境ストレスに応答する脳内カンナビノイドシステムの解析
- Principal Investigator
  
  藤原道弘
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Fukuoka University
PPARγplays an important role in improvement of cognitive decline in Alzheimer's disease model animals complicated by lifestyle deseases.
- Principal Investigator
  
  IWASAKI Katsunori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Fukuoka University
Extraction of water soluble beta-1,3 glucan with a Macchinetta extractor
- Principal Investigator
  
  SHIGEMATSU Mikiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Wood science
- Research Institution
  Fukuoka University
Study for regeneration of function in neonatal hypoxic-ischemic encephalopathy using animal model of slowly progressive brain damage in ratsPrincipal Investigator
- Principal Investigator
  
  MISHIMA Kenichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
Pharmacological studies in accelerating mechanism of Alzheimer's disease by diabetes mellitus with insulin resistance in rats
- Principal Investigator
  
  IWASAKI Katsunori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
Study on impaired social interaction in cannabis-treated and psychiatric animals
- Principal Investigator
  
  EGASHIRA Nobuaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kyushu University
  Fukuoka University
Pharmacological studies in the animal model for Alzheimer' s disease with life-style related disease
- Principal Investigator
  
  IWASAKI Katsunori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  FUKUOKA UNIVERSITY
Investigation of cerebral paralysis and its development of new drugs in neonatal hypoxic-ischemia-induced slowly progressive brain damagePrincipal Investigator
- Principal Investigator
  
  MISHIMA Kenichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
Investigation of mechanisms mediating pubertal treatment of marihuana-induced psychosis
- Principal Investigator
  
  EGASHIRA Nobuaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Fukuoka University
The novel role of the spinal muscarinic receptors in pain.
- Principal Investigator
  
  TAKANO Yukio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Fukuoka University
Molecular pharmacological studies in the animal model for Alzheimer's disease
- Principal Investigator
  
  IWASAKI Katsunori
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Fukuoka University
精神障害モデルとしての大麻による異常行動発現機構の解明Principal Investigator
- Principal Investigator
  
  三島健一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Fukuoka University

[Book] In Handbook of Green Tea and Health Research(Edited by Mckinley H. and Jamieson M. Neuroprotective effect of theanine on cerebral ischemia ISBN:978-1-60741-045-4)2009
- Author(s)
  Egashira N, Mishima K, Iwasaki K, Oishi R, Fujiwara M
- Publisher
  Nova Science Publishers, Inc., N.Y.
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Haptoglobin Regulates Macrophage/Microglia-Induced Inflammation and Prevents Ischemic Brain Damage Via Binding to HMGB12022
- Author(s)
  Morimoto M, Nakano T, Egashira S, Irie K, Matsuyama K, Wada M, Nakamura Y, Shigemori Y, Ishikura H, Yamashita Y, Hayakawa K, Sano K, Mishima K
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 11 Issue: 6
- DOI
  10.1161/jaha.121.024424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07215, KAKENHI-PROJECT-19K16432
[Journal Article] Therapeutic effect of anti-HMGB1 antibody in a mouse model of 4-h middle cerebral artery occlusion: comparison with tissue plasminogen activator2022
- Author(s)
  Nakano Takafumi、Tagashira Yui、Egashira Saki、Morimoto Mayuka、Irie Keiichi、Hosokawa Masato、Hayashi Toshinobu、Egawa Takashi、Hayakawa Kazuhide、Mishima Kenichi
- Journal Title
  
  NeuroReport
  
  Volume: 33 (7) Issue: 7 Pages: 297-303
- DOI
  10.1097/wnr.0000000000001780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07215, KAKENHI-PROJECT-19K16432
[Journal Article] Antithrombin gamma attenuates macrophage/microglia activation and brain damage after transient focal cerebral ischemia in mice2020
- Author(s)
  Nakano T, Nakamura Y, Irie K, Okano S, Morimoto M, Yamashita Y, Kozako T, Hayashi T, Honda SI, Matsuo K, Kamimura H, Ishikura H, Egawa T, Mishima K.
- Journal Title
  
  Life Sci
  
  Volume: 252 Pages: 117665-117665
- DOI
  10.1016/j.lfs.2020.117665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08851, KAKENHI-PROJECT-20K07215, KAKENHI-PROJECT-19K16432
[Journal Article] Long-Term Treatment with Thrombomodulin Improves Functional Outcomes after Cerebral Ischemia Even if Administration is Delayed.2019
- Author(s)
  Takafumi Nakano, Yoshihiko Nakamura, Kiyoshi Matsuyama, Keiichi Irie, Mako Yasumura, Yurie Hirata, Motoki Yamasaki, Kanae Misumi, Yuta Yamashita, Takayuki Myose, Koichi Matsuo, Kazunori Sano, Hidetoshi Kamimura, Hiroyasu Ishikura, Takashi Egawa, Kenichi Mishima
- Journal Title
  
  Thromb Haemost
  
  Volume: 119 Issue: 03 Pages: 467-478
- DOI
  10.1055/s-0038-1677532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08433, KAKENHI-PROJECT-17H07300
[Journal Article] Goreisan Prevents Brain Edema after Cerebral Ischemic Stroke by Inhibiting Aquaporin 4 Upregulation in Mice2018
- Author(s)
  Takafumi Nakano, Chisa Nishigami, Keiichi Irie, Yutaka Shigemori, Kazunori Sano, Yuta Yamashita, Takayuki Myose, Koji Tominaga, Koichi Matsuo, Yoshihiko Nakamura, Hiroyasu Ishikura, Hidetoshi Kamimura, Takashi Egawa, Kenichi Mishima
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 27 Issue: 3 Pages: 758-763
- DOI
  10.1016/j.jstrokecerebrovasdis.2017.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08433, KAKENHI-PROJECT-26462170, KAKENHI-PROJECT-17H07300
[Journal Article] 脳梗塞モデルマウスに対する播種性血管内凝固症候群治療薬トロンボモデュリンアルファの効果2017
- Author(s)
  三島健一、藤岡政行、仲村佳彦、中野貴文、入江圭一
- Journal Title
  
  福岡大学産学官連携研究機関　加齢脳科学研究所　2016年度研究成果報告書
  
  Volume: - Pages: 53-61
- Data Source
  KAKENHI-PROJECT-26462170
[Journal Article] Role of vasopressin V1a receptor in Δ9-tetrahydrocannabinol-induced cataleptic immobilization in mice.2017
- Author(s)
  Nobuaki Egashira, Emi Koushi, Takayuki Myose, Akito Tanoue, Kenichi Mishima, Ryota Tsuchihashi, Junei Kinjo, Hiroyuki Tanaka, Satoshi Morimoto, Katsunori Iwasaki
- Journal Title
  
  Psychopharmacology
  
  Volume: 234 Issue: 23-24 Pages: 3475-3483
- DOI
  10.1007/s00213-017-4735-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08606
[Journal Article] Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice.2016
- Author(s)
  Nakamura Y, Nakano T, Irie K, Sano K, Tanaka J, Yamashita Y, Satho T, Matsuo K, Fujioka M, Ishikura H, Mishima K.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 362 Pages: 278-282
- DOI
  10.1016/j.jns.2016.01.047
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Journal Article] Evaluation of a filament perforation model for mouse subarachnoid hemorrhage using 7.0 Tesla MRI2016
- Author(s)
  Muroi C, Kashiwagi Y, Rokugawa T, Tonomura M, Obata A, Nevzati E, Tsuboi A, Okuchi K, Mishima K, Abe K, Fujioka M
- Journal Title
  
  J Clin Neurosci.
  
  Volume: 28 Pages: 141-147
- DOI
  10.1016/j.jocn.2015.10.045
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170, KAKENHI-PROJECT-15K14335, KAKENHI-PUBLICLY-15H01446, KAKENHI-PROJECT-25290015, KAKENHI-PROJECT-16H04664
[Journal Article] Delayed treatment with ADAMTS13 ameliorates cerebral ischemic injury without hemorrhagic complication2015
- Author(s)
  Nakano T, Irie K, Hayakawa K, Sano K, Nakamura Y, Tanaka M, Yamashita Y, Satho T, Fujioka M, Muroi C, Matsuo K, Ishikura H, Futagami K, Mishima K.
- Journal Title
  
  Brain Res.
  
  Volume: 1624 Pages: 330-335
- DOI
  10.1016/j.brainres.2015.07.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Journal Article] Mouse model of subarachnoid hemorrhage: technical note on the filament perforation model.2015
- Author(s)
  Muroi C, Fujioka M, Marbacher S, Fandino J, Keller E, Iwasaki K, Mishima K.
- Journal Title
  
  Acta Neurochir Suppl. 2015;120:315-20.
  
  Volume: 120 Pages: 315-320
- DOI
  10.1007/978-3-319-04981-6_54
- ISBN
  9783319049809, 9783319049816
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Journal Article] Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage.2014
- Author(s)
  Muroi C, Fujioka M, Mishima K, Irie K, Fujimura Y, Nakano T, Fandino J, Keller E, Iwasaki K, Fujiwara M.
- Journal Title
  
  J Thromb Haemost.
  
  Volume: 12(4) Issue: 4 Pages: 505-514
- DOI
  10.1111/jth.12511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654, KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-26462170
[Journal Article] Filament perforation model for mouse subarachnoid hemorrhage: Surgical-technical considerations2014
- Author(s)
  Muroi C, Fujioka M, Okuchi K, Fandino J, Keller E, Sakamoto Y, Mishima K, Iwasaki K, Fujiwara M
- Journal Title
  
  Br J Neurosurg
  
  Volume: 28 Issue: 6 Pages: 722-732
- DOI
  10.3109/02688697.2014.918579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462170
[Journal Article] Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage2014
- Author(s)
  Muroi C, Fujioka M, Mishima K, Irie K, Fujimura Y, Nakano T, Fandino J, Keller E, Iwasaki K, Fujiwara M
- Journal Title
  
  J Thromb Haemost
  
  Volume: 12(4) Pages: 505-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Allogeneic Transplantation of Fetal Membrane-Derived Mesenchymal Stem Cell Sheets Increases Neovascularization and Improves Cardiac Function after Myocardial Infarction in Rats2013
- Author(s)
  Ishikane S, Hosoda H, Yamahara K, Akitake Y, Kyoungsook J, Mishima K, Iwasaki K, Fujiwara M, Miyazato M, Kangawa K, Ikeda T
- Journal Title
  
  Transplantation
  
  Volume: 96(8) Pages: 697-706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Correlation among systemic inflammatory parameter, occurrence of delayed neurological deficits, and outcome after aneurysmal subarachnoid hemorrhage2013
- Author(s)
  Muroi C, Hugelshofer M, Seule M, Tastan I, Fujioka M, Mishima K, Keller E
- Journal Title
  
  Neurosurgery
  
  Volume: 72(3) Pages: 367-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Bioimaging application of highly luminescent silica-coated ZnO-nanoparticle quantum dots with biotin2013
- Author(s)
  Matsuyama K, Ihsan N, Irie K, Mishima K, Okuyama T, Muto H
- Journal Title
  
  J Colloid Interface Sci
  
  Volume: 399 Pages: 19-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Transparent polymeric hybrid film of ZnO nanoparticle quantum dots and PMMA with high luminescence and tunable emission color2012
- Author(s)
  Matsuyama K, Mishima K, Kato T, Irie K, Mishima K
- Journal Title
  
  J Colloid Interface Sci
  
  Volume: 367(1) Pages: 171-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Involvement of opioid system in cognitive deficits induced by d9-tetrahydrocannabinol in rats2012
- Author(s)
  Nobuaki Egashira, Naomi Manome,Kenichi Mishima, Katsunori Iwasaki, Ryozo Oishi, Michihiro Fujiwara
- Journal Title
  
  Psychopharmacology
  
  Volume: 219 Issue: 4 Pages: 1111-1118
- DOI
  10.1007/s00213-011-2442-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591685
[Journal Article] Novel treatments for vasospasm after subarachnoid hemorrhage2012
- Author(s)
  Muroi C, Seule M, Mishima K, Keller E
- Journal Title
  
  Curr Opin Crit Care
  
  Volume: 18(2) Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury2012
- Author(s)
  Fujioka M, Nakano T, Hayakawa K, Irie K, Akitake Y, Sakamoto Y, Mishima K, Muroi C, Yonekawa Y, Banno F, Kokame K, Miyata T, Nishio K, Okuchi K, Iwasaki K, Fujiwara M, Siesjö BK
- Journal Title
  
  Neurol Sci
  
  Volume: 33(5) Pages: 1107-1115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Preferential involvement of Na(+)/Ca(2+) exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice2012
- Author(s)
  Morimoto N, Kita S, Shimazawa M, Namimatsu H, Tsuruma K, Hayakawa K, Mishima K, Egashira N, Iyoda T, Horie I, Gotoh Y, Iwasaki K, Fujiwara M, Matsuda T, Baba A, Komuro I, Horie K, Takeda J, Iwamoto T, Hara H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 429(3-4) Pages: 186-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Correlation between Systemic Inflammatory Parameter, Occurrence of Delayed Neurological Deficits and Outcome after Aneurysmal Subarachnoid Hemorrhage2012
- Author(s)
  Muroi C, Hugelshofer M, Seule M, Tastan I, Fujioka M, Mishima K, Keller E
- Journal Title
  
  Neurosurgery
  
  Volume: 72(3) Pages: 367-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Magnesium and the inflammatory response: potential pathophysiological implications in the management of patients with aneurysmal subarachnoid hemorrhage?2012
- Author(s)
  Muroi C、 Burkhardt JK、 Hugelshofer M、 Seule M、 Mishima K、 Keller E
- Journal Title
  
  Magnes Res.
  
  Volume: 25 Pages: 64-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Magnesium and the inflammatory response : potential pathophysiological implications in the management of patients with aneurysmal subarachnoid hemorrhage?2012
- Author(s)
  Muroi C, Burkhardt JK, Hugelshofer M, Seule M, Mishima K, Keller E
- Journal Title
  
  Magnes Res
  
  Volume: 25(2) Pages: 64-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion iniury2012
- Author(s)
  M.Fujioka, 他16名
- Journal Title
  
  Neurol Sci
  
  Volume: 33 Issue: 5 Pages: 1107-1115
- DOI
  10.1007/s10072-011-0913-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390278, KAKENHI-PROJECT-21592313, KAKENHI-PROJECT-22570151, KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23590654, KAKENHI-PROJECT-23659494, KAKENHI-PROJECT-24390250
[Journal Article] Ameliorative effects of telmisartan on the inflammatory response and impaired spatial memory in a rat model of Alzheimer's disease incorporating additional cerebrovascular disease factors2012
- Author(s)
  Shindo T, Takasaki K, Uchida K, Onimura R, Kubota K, Uchida N, Irie K, Katsurabayashi S, Mishima K, Nishimura R, Fujiwara M, Iwasaki K
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35(12) Pages: 2141-7
- NAID
  130002480503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Novel treatments for vasospasm after subarachnoid hemorrhage.2012
- Author(s)
  Muroi C、 Seule M、 Mishima K、 Keller E.
- Journal Title
  
  Curr Opin Crit Care.
  
  Volume: 18 Issue: 2 Pages: 119-126
- DOI
  10.1097/mcc.0b013e32835075ae
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Effects of yokukansan on anxiety- like behavior in a rat model of cerebrovascular dementia2011
- Author(s)
  Nogami A, Sakata Y, Uchida N, Yamaguchi K, Kawasaki C, Shindo T, Kubota K, Katsurabayashi S, Takasaki K, Mishima K, Nishimura R, Fujiwara M, Iwasaki K
- Journal Title
  
  J Nat Med
  
  Volume: 65(2) Pages: 275-281
- NAID
  10029461153
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] Neuroprotective effects of citidine-5-diphosphocholine on impaired spatial memory in a rat model of cerebrovascular dementia2011
- Author(s)
  Takasaki K, Uchida K, Fujikawa R, Nogami A, Nakamura K, Kawasaki C, Yamaguchi K, Morita M, Morishita K, Kubota K, Katsurabayashi S, Mishima K, Fujiwara M, Iwasaki K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116(2) Pages: 232-7
- NAID
  10029894890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590654
[Journal Article] ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating post-ischemic hypoperfusion2010
- Author(s)
  Fujioka M, Hayakawa K, Mishima K, Kunizawa A, Irie K, Higuchi S, Nakano T, Muroi C, Fukushima H, Sugimoto M, Banno F, Kokame K, Miyata T, Fujiwara M, Okuchi K, Nishio K
- Journal Title
  
  Blood 115(8)
  
  Pages: 1650-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Sex differences in the benefits of rehabilitative training during adolescence following neonatal hypoxia-ischemia in rats2010
- Author(s)
  Tsuji M, Aoo N, Harada K, Sakamoto Y, Akitake Y, Irie K, Mishima K, Ikeda T, Fujiwara M
- Journal Title
  
  Exp Neurol. 226(2)
  
  Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Ameliorating effects of Kangen-karyu on neuronal damage in rats subjected to repeated cerebral ischemia2010
- Author(s)
  Pu F, Kaneko T, Enoki M, Irie K, Okamoto T, Sei Y, Egashira N, Oishi R, Mishima K, Kamimura H, Iwasaki K, Fujiwara M
- Journal Title
  
  J Nat Med. 64(2)
  
  Pages: 167-174
- NAID
  10027709454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia2010
- Author(s)
  Haraguchi T, Iwasaki K, Takasaki K, Uchida K, Naito T, Nogami A, Kubota K, Shindo T, Uchida N, Katsurabayashi S, Mishima K, Nishimura R, Fujiwara M.
- Journal Title
  
  Brain Res
  
  Volume: 24 Pages: 125-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590298
[Journal Article] Allogeneic administration of fetal membrane-derived mesenchymal stem cells attenuates acute myocarditis in rats2010
- Author(s)
  Ishikane S, Yamahara K, Sada M, Harada K, Kodama M, Ishibashi-Ueda H, Hayakawa K, Mishima K, Iwasaki K, Fujiwara M, Kangawa K, Ikeda T
- Journal Title
  
  J Mol Cell Cardiol. 49(5)
  
  Pages: 753-761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Dynamin 1 depletion and memory deficits in rats treated with A-beta and cerebral ischemia2010
- Author(s)
  Watanabe T, Iwasaki K, Takasaki K, Yamagata N, Fujino M, Nogami A, Ii M, Katsurabayashi S, Mishima K, Fujiwara M
- Journal Title
  
  Journal of Neuriscience Research
  
  Volume: 88 Pages: 1908-1917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590298
[Journal Article] Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice2010
- Author(s)
  Hayakawa K, Nakano T, Irie K, Higuchi S, Fujioka M, Orito K, Iwasaki K, Jin G, Lo EH, Mishima K, Fujiwara M
- Journal Title
  
  J Cereb Blood Flow Metab. 30(4)
  
  Pages: 871-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Telmisartan, a partial agonist of peroxisome proliferator-activated recept or gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia.2010
- Author(s)
  Haraguchi T, Iwasaki K, Takasaki K, Uchida K, Naito T, Nogami A, Kubota K, Shindo T, Uchida N, Katsurabayashi S, Mishima K, Nishimura R, Fujiwara M.
- Journal Title
  
  Brain Research
  
  Volume: 1353 Pages: 125-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590298
[Journal Article] Cerebroprotective action of telmisartan by inhibition of macrophages/microglia expressing HMGB1 via a peroxisome proliferator-activated receptorgamma-dependent mechanism2009
- Author(s)
  Haraguchi T, Takasaki K, Naito T, Hayakawa K, Katsurabayashi S, Mishima K, Iwasaki K, Fujiwara M.
- Journal Title
  
  Neurosci Lett. VOL.464
  
  Pages: 151-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590298
[Journal Article] Therapeutic time window of cannabidiol treatment on delayed ischemic damage via high-mobility group box1-inhibiting mechanism2009
- Author(s)
  Hayakawa K, Irie K, Sano K, Watanabe T, Higuchi S, Enoki M, Nakano T, Harada K, Ishikane S, Ikeda T, Fujioka M, Orito K, Iwasaki K, Mishima K, Fujiwara M
- Journal Title
  
  Biol Pharm Bull. 32(9)
  
  Pages: 1538-44
- NAID
  130000117280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Neuroprotective effects of Kangen-karyu on spatial memory impairment in an 8-arm radial maze and neuronal death in the hippocampal CA1 region induced by repeated cerebral ischemia in rats2009
- Author(s)
  Pu F, Motohashi K, Kaneko T, Tanaka Y, Manome N, Irie K, Takata J, Egashira N, Oishi R, Okamoto T, Sei Y, Yokozawa T, Mishima K, Iwasaki K, Fujiwara M
- Journal Title
  
  J Pharmacol Sci. 109(3)
  
  Pages: 424-340
- NAID
  10025735292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Cerebroprotective action of telmisartan by inhibition of macrophages/microglia expressing HMGB1 via a peroxisome proliferator-activated receptor gamma-dependent mechanism2009
- Author(s)
  Haraguchi T, Takasaki K, Naito T, Hayakawa K, Katsurabayashi S, Mishima K, Iwasaki K, Fujiwara M.
- Journal Title
  
  Neurosci Lett
  
  Volume: 464(3) Pages: 151-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590298
[Journal Article] Delayed treatment with minocycline improves neurological impairment via activated microglia expressing high-mobility group box1 inhibiting mechanism2008
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Irie K, Hazekawa M, Mishima S, Fujioka M, Orito K, Egashira N, Iwasaki K, Fujiwara M
- Journal Title
  
  Stroke 39(3)
  
  Pages: 951-958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Spatial memory impairment without apoptosis induced by the combination of beta-amyloid oligomers and cerebral ischemia is related to decreasedacetylcholine release in rats2008
- Author(s)
  Watanabe T, Iwasaki K, Ishikane S, Naitou T, Yoshimitsu Y, Yamagata N, Ozdemir MB, Takasaki K, Egashira N, Mishima K, Fujiwara M.
- Journal Title
  
  J Pharmacol Sci 106
  
  Pages: 84-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590545
[Journal Article] Allogeneic injection of fetal membrane-derived mesenchymal stem cells induces therapeutic angiogenesis in a rat model of hind limb ischemia2008
- Author(s)
  Ishikane S, Ohnishi S, Yamahara K, Sada M, Harada K, Mishima K, Iwasaki K, Fujiwara M, Kitamura S, Nagaya N, Ikeda T
- Journal Title
  
  Stem Cells. 26(10)
  
  Pages: 2625-2633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism2008
- Author(s)
  Hayakawa K, Mishima K, Irie K, Hazekawa M, Mishima S, Fujioka M, Orito K, Egashira N, Katsurabayashi S, Takasaki K, Iwasaki K, Fujiwara M
- Journal Title
  
  Neuropharmacology 55(8)
  
  Pages: 1280-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590552
[Journal Article] Comparison of Single-and Repeated-Ischemia-Induced Changes in Expression of Flip and Flop Splice Variants of AMPA Receptor Subtypes GluR1 and GluR2 in the Rats Hippocampus CA1 Subregion.2007
- Author(s)
  Hatip-Al-Khatib I, Iwasaki K, Egashira N, Ishibashi D, Mishima K, Fujiwara M.
- Journal Title
  
  Journal of Pharmacological Sciences 30
  
  Pages: 698-701
- NAID
  10024312106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia.2007
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Hazekawa M, Ogata A, Fujioka M, Harada K, Mishima S, Orito K, Egashira N, Iwasaki K, Fujiwara M
- Journal Title
  
  Life Sci. 80
  
  Pages: 1466-1471
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia.2007
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Hazekawa M, Ogata A, Fujioka M, Harada K, Mishima S, Orito K, Egashira N, Iwasaki K, Fujiwara M.
- Journal Title
  
  Life Sci. 80
  
  Pages: 1466-1471
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Comparison of Single- and Repeated-Ischemia-Induced Changes in Expression of Flip and Flop Splice Variants of AMPA Receptor Subtypes G1uR1 and GluR2 in the Rats Hippocampus CA1 Subregion.2007
- Author(s)
  Hatip-Al-Khatib I, Iwasaki K, Egashira N, Ishibashi D, Mishima K, Fujiwara M
- Journal Title
  
  Journal of Pharmacological Sciences 103
  
  Pages: 83-91
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Comparison of Single-and Repeated-Ischemia-Induced Changes in Expression of Flip and Flop Spice Variants of AMPA Receptor Subtypes GluR1 and GluR2 in the Rats Hippocampus CA1 Subregion2007
- Author(s)
  Hatip-A1-Khatib I, Iwasaki K, Egashira N, Ishibashi D, Mishima K, Fujiwara M
- Journal Title
  
  J Pharmacol Sci. 103巻1号
  
  Pages: 83-91
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia.2007
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Hazekawa M, Ogata A, Fujioka M, Harada K, Mishima S, Orito K, Egashira N, Iwasaki K, Fjiwara M
- Journal Title
  
  Life Sci. in press
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] High-cholesterol feeding aggravates cerebral infarction via decreasing the CB(1) receptor.2007
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Hazekawa M, Aoyama Y, Ogata A, Harada K, Fujioka M, Abe K, Egashira N, Iwasaki K, Fujiwara M.
- Journal Title
  
  Neurosci Lett. 414
  
  Pages: 183-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Comparison of Single- and Repeated-Ischemia-Induced Changes in Expression of Flip and Flop Splice Variants of AMPA Receptor Subtypes GluR1 and GluR2 in the Rats Hippocampus CA1 Subregion.2007
- Author(s)
  Hatip-Al-Khatib I, Iwasaki K, Egashira N, Ishibashi D, Mishima K, Fujiwara M
- Journal Title
  
  J Pharmacol Sci. 103
  
  Pages: 83-91
- NAID
  10024312106
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Nilvadipine prevents the impairment of spatial memory induced by cerebral ischemia combined with be-ta-anyloid in rats.2007
- Author(s)
  Iwasaki, K, Egashira N, Takagaki, Y, Yoshimitsu, Y, Hatip-Al-Khatib I, Mishima, K, Fujiwara, M
- Journal Title
  
  Biological ＆ Pharmacceutical Bulletin 30
  
  Pages: 698-701
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Nilvadipine prevents the impairment of spatial memory induced by cerebral ischemia combined with be-ta-amyloid in rats.2007
- Author(s)
  Iwasaki, K, Egashira N, Takagaki, Y, Yoshimitsu, Y, Hatip-Al-Khatib I, Mishima, K, Fujiwara, M
- Journal Title
  
  Biological ＆ Pharmacceutical Bulletin 30
  
  Pages: 698-701
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] High-cholesterol feeding aggravates cerebral infarction via decreasing the CB(1) receptor.2007
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Hazekawa M, Aoyama Y, Ogata A, Harada K, Fujioka M, Abe K, Egashira N, Iwasaki K, Fujiwara M
- Journal Title
  
  Neurosci Lett. 414
  
  Pages: 183-187
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Cerebral ischemia combined with beta-amyloid impairs spatial memory in the eight-arm radial maze task in rats2006
- Author(s)
  Iwasaki K, Egashira N, Hatip-Al-Khatibl, Akiyoshi Y, Arai T, Takagaki Y, Watanabe T, Mishima K, Fujiwara M
- Journal Title
  
  Brain Research 1097巻1号
  
  Pages: 216-223
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male nice.2006
- Author(s)
  Umehara F, Mishima K, Egashira N, Ogata A, Iwasaki K, Fujiwara M
- Journal Title
  
  Behav Brain Res. 174
  
  Pages: 167-173
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] High-cholesterol feeding aggravates cerebral infarction via decreasing the CB(1) receptor.2006
- Author(s)
  Hayakawa K, Mishima K, Nozako M, Hazekawa M, Aoyama Y, Ogata A, Harada K, Fujioka M, Abe K, Egashira N, Iwasaki K, Fujiwara M
- Journal Title
  
  Neurosci Lett. in press
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Rehabilitative training tasks improve spatial learning impairment in the water maze following hypoxic-ischemic insult in neonatal rats.2006
- Author(s)
  Ikeda T, Mishima K, Aoo N, Harada K, Liu AX, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T.
- Journal Title
  
  Pediatr Res. 59
  
  Pages: 61-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Cerebral ischemia combined with beta-amyloid impairs spatial memory in the eight-arm radial maze task in rats.2006
- Author(s)
  Iwasaki, K, Egashira, N, Hatip-Al-Khatib, I, Akiyoshi, Y, Takagaki, Y, Watanabe, T, Mishima, K, Fujiwara, M
- Journal Title
  
  Brain Research 1097
  
  Pages: 216-223
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo.2006
- Author(s)
  Ochiai T, Shimeno H, Mishima KI, Iwasaki K, Fujiwara M, Tanaka H, Shoyama Y, Toda A, Eyanagi R, Soeda S
- Journal Title
  
  Biochim Biophys Acta. in press
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Investigation of mechanisms mediating 8-OH-DPAT-induced impairment of spatial memory : Involvement of 5-HT(IA)receptors in the dorsal hippocampus in rats.2006
- Author(s)
  Egashira N, Yano A, Ishigami N, Mishima K, Iwasaki K, Fujioka M, Matsushita M, Nishimura R, Fujiwara M
- Journal Title
  
  Brain Research 1069巻1号
  
  Pages: 54-62
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Cerebral ischemia combined with beta-amyloid impairs spatial memory in the eight-arm radial maze task in rats.2006
- Author(s)
  Iwasaki, K, Egashira, N, Hatip-Al-Khatib, I, Akiyoshi, Y, Takagaki, Y, Watanabe, T, Mishima, K, Fujiwara,M
- Journal Title
  
  Brain Research 1097
  
  Pages: 216-223
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Rehabilitative training tasks improve spatial learning impairment in the water maze following hypoxic-ischemic insult in neonatal rats.2006
- Author(s)
  Ikeda T, Mishima K, Aoo N, Harada K, Liu AX, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T
- Journal Title
  
  Pediatr Res. 59
  
  Pages: 61-65
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Implantation of encapsulated glial cell line-derived neurotrophic factor-secreting cells prevents long-lasting learning impairment of following neonatal hypoxic-ischemic brain insult in rats.2005
- Author(s)
  Katsuragi S, Ikeda T, Date I, Shingo T, Yasuhara T, Mishima K, Aoo N, Harada K, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T
- Journal Title
  
  Am J Obstet Gyneco 192
  
  Pages: 1028-1037
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Implantation of encapsulated glial cell line-derived neurotrophic factor-secreting cells prevents long-lasting learning impairment following neonatal hypoxic-ischemic brain insult in rats.2005
- Author(s)
  Katsuragi S, Ikeda T, Date I, Shingo T, Yasuhara T, Mishima K, Aoo N, Harada K, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T
- Journal Title
  
  Am J Obstet Gyneco 192
  
  Pages: 1028-1037
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Altered depression-related behavior and neurochemical changes in serotonergic neurons in mutant R406W human tau transgenic mice2005
- Author(s)
  Egashira, N, Iwasaki, K, Takashima, A, Watanabe, T, Kawabe, H, Matsuda, T, Mishima, K.Fujiwara, M
- Journal Title
  
  Brain Research 1059
  
  Pages: 7-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Short-Term Administration of a New Free Radical Scavenger, Edaravone, Is More Effective Than its Long-Term Administration for the Treatment of Neonatal Hypoxic-Ischemic Encephalopathy.2005
- Author(s)
  Noor JI, Ikeda T, Mishima K, Aoo N, Ohta S, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T.
- Journal Title
  
  Stroke 36
  
  Pages: 2468-2474
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Protective effect of Toki-shakuyaku-san on amyloid β25-35-induced neuronal damage in cultured rat cortical neurons2005
- Author(s)
  Egashira, N, Iwasaki, K, Akiyoshi, Y, Takagaki, Y, Hatip-Al-Khatib, I, Mishima, K, Ikeda, T, Fujiwara,M
- Journal Title
  
  Phytotherapy Research 19
  
  Pages: 450-453
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Altered depression-related behavior and neurochemical changes in serotonergic neurons in mutant R406W human tau transgenic mice2005
- Author(s)
  Nobuaki EGASKIRA, Katsunori IWASAKI, Akihiko TAKASHIMA, Takuya WATANABE, Hideyuki KAWABE, Tomomi MATSUDA, Kenichi MISHIMA, Shozo CHIDORI, Ryoji NiSHIMURA, Michihiro FUJIWARA
- Journal Title
  
  Brain Research 1059
  
  Pages: 2468-2474
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats2005
- Author(s)
  Hatip-Al-Khatib, I, Iwasaki, K, Yoshimitsu, Y, Arai, T, Egashira, N, Mishima, K, Fujiwara.M
- Journal Title
  
  British Journal of Pharmacology 145
  
  Pages: 1035-1044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats2005
- Author(s)
  Izzettin HATIP-AL-KHATIB, Katsunori IWASAKI, Yoshimitsu YOSHITAKA, Takashi ARAI, Nobuaki EGASHIRA, Kenichi MISHIMA, Tomoaki IKEDA, Michihiro FUJIWARA
- Journal Title
  
  British Journal of Pharmacology 145
  
  Pages: 1035-1044
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Protective effect of Toki-shakuyaku-san on amyloid β25-35-induced neuronal damage in cultured rat cortical neurons2005
- Author(s)
  Nobuaki EGASHIRA, Katsunori IWASAKI, Yuki AKIYOSHI, Yuki TAKAGAKI, Izzettin AL-KHATI B, Kenichi MISHIMA, Kouji KURAUCHI, Tomoaki IKEDA, Michihiro FUJIWARA
- Journal Title
  
  Phytotherapy Research 19巻
  
  Pages: 450-453
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Altered depression-related behavior and neurochemical changes in serotonergic neurons in mutant R406W human tau transgenic mice2005
- Author(s)
  Egashira, N, Iwasaki, K, Takashima, A, Watanabe, T, Kawabe, H, Matsuda, T, Mishima, K, Fujiwara,M
- Journal Title
  
  Brain Research 1059
  
  Pages: 7-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Protective effect of Toki-shakuyaku-san on amyloid B325-35-induced neuronal damage in cultured rat cortical neurons Hatip-Al-2005
- Author(s)
  Egashira, N, Iwasaki, K., Akiyoshi, Y, Takagaki, Y, Hatip-Al-Khatib, I, Mishima, K, Ikeda, T, Fujiwara, M
- Journal Title
  
  Phytotherapy Research 19
  
  Pages: 450-453
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Hypoxia-ischemic insult in neonatal rats induced slowly progressive brain damage related to memory impairment2005
- Author(s)
  Mishima K, Ikeda T, Aoo N, Takai N, Takahashi S, Egashira N, Ikenoue T, Iwasaki K, Fujiwara M
- Journal Title
  
  Neurosci Lett. 376
  
  Pages: 194-199
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats2005
- Author(s)
  Hatip-Al-Khatib, I, Iwasaki, K, Yoshimitsu, Y, Arai, T, Egashira, N, Mishima, K, Fujiwara,M
- Journal Title
  
  British Journal of Pharmacology 145
  
  Pages: 1035-1044
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Post-ischemic treatment with toki-shakuyaku-san(tang-gui-shao-yao-san)prevents the impairment of spatial memory induced by repeated cerebral ischemia in rats.2005
- Author(s)
  Pu F, Mishima K, Egashira N, Akiyoshi Y, Liu AX, Sano K, Irie K, Ishibashi D, Hatip-Al-Khatib I, Iwasaki K, Kurauchi K, Iwasaki K, Fujiwara M
- Journal Title
  
  Am J Chin Med. 33
  
  Pages: 475-489
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Short-Term Administration of a New Free Radical Scavenger, Edaravone, Is More Effective Than its Long-Term Administration for the Treatment of Neonatal Hypoxic-Ischemic Encephalopathy.2005
- Author(s)
  Noor JI, Ikeda T, Mishima K, Aoo N, Ohta S, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T
- Journal Title
  
  Stroke 36
  
  Pages: 2468-2474
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] 脳虚血とβ-アミロイド投与による新しいアルツハイマー病モデル動物の作成とニルバジピンの有効性2005
- Author(s)
  岩崎克典, 江頭伸昭, 秋吉祐樹, 高垣祐紀, 新井隆, 三島健一, 藤原道弘
- Journal Title
  
  Pharma Medica 23巻
  
  Pages: 143-155
- Data Source
  KAKENHI-PROJECT-17500266
[Journal Article] Canabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptaminel A Recepter-Dependent Mechanism.2005
- Author(s)
  Mishima K, Hayakawa K, Abe K, Ikeda T, Egashira N, Iwasaki K, Fujiwara M.
- Journal Title
  
  Stroke 36
  
  Pages: 1071-1076
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptaminelA receptor-dependent mechanism2005
- Author(s)
  Kenichi Mishima
- Journal Title
  
  Stroke 36巻5号
  
  Pages: 1071-1076
- Data Source
  KAKENHI-PROJECT-16591174
[Journal Article] Dexamethasone prevents long-lasting learning impairment following a combination of lipopolysaccharide and hypoxia-ischemia in neonatal rats.2005
- Author(s)
  Ikeda T, Mishima K, Aoo N, Liu AX, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T
- Journal Title
  
  Am J Obstet Gyneco 192
  
  Pages: 719-726
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590479
[Journal Article] 「研究成果報告書概要(欧文)」より2004
- Author(s)
  Egashira, N., Egashira, Tanoue, A., Higashihara, F., Mishima, K., Fukue, Y., Takano, Y., Tujimoto, G., Iwasaki, K., Fujiwara, M.
- Journal Title
  
  Neurosci. Lett. 356
  
  Pages: 195-198
- Data Source
  KAKENHI-PROJECT-14572170
[Journal Article] Characteristics of behavioral abnor- malities in αld-adrenoceptors deficient mice.2004
- Author(s)
  Mishima, K., Tanoue, A., Tsuda, M., Hasebe, N., Fukue, Y, N.Egashira, N., Takano, Y, Kamiya, H., Tujimoto, G.., Iwasaki, K., Fujiwara, M.
- Journal Title
  
  Behav. Brain Res. 152
  
  Pages: 365-373
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572170
[Journal Article] Characteristics of behavioral abnormalities in α_<1d>-adrenoceptors deficient mice2004
- Author(s)
  K.Mishima
- Journal Title
  
  Behav.Brain Res. 152
  
  Pages: 365-373
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572170
[Journal Article] Characteristics of behavioral abnormalities in α_<1d>-adrenoceptors deficient mice2004
- Author(s)
  K.Mishima
- Journal Title
  
  Behav. Brain Res. 152
  
  Pages: 365-373
- Data Source
  KAKENHI-PROJECT-14572170
[Patent] 血栓形成予防薬として利用されるADAMTS13誘導剤2011
- Inventor(s)
  入江圭一, 藤原道弘, 岩橋克典, 三島健一, 中野貴文, 片岡泰文, 山内淳史, 佐藤朝光, 坂元佑哉, 平松征洋, 川崎圭祐
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2013-056861
- Filing Date
  2011-09-09
- Overseas
- Data Source
  KAKENHI-PROJECT-23590654
[Patent] 生体試料中2-アラキドノイルグリセロールの定量法2010
- Inventor(s)
  入江圭一、藤原道弘、三島健一、樋口聖、三島健司、早川和秀、佐野和憲、佐藤朝光、秋武義治、荒木舞子、大治万喜子
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Number
  2010-234486
- Filing Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-20590552
[Patent] 母乳由来の脂質およびその誘導体を有効成分とする抗菌ペプチドの発現誘導剤あるいは産生促進剤2009
- Inventor(s)
  佐藤朝光,藤原道弘,入江圭一,三島健一,見明史雄,鹿志毛信広,早野智大,添田秦司
- Industrial Property Rights Holder
  福岡大学
- Industrial Property Number
  2009-121853
- Filing Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] 脳梗塞モデルマウスにおけるSerum Amyloid A(SAA)の動態2023
- Author(s)
  江頭早紀、真崎有裕子、向井梨恵、中野貴文、細川雅人、亀谷富由樹、入江圭一、佐藤朝光、山下郁太、佐野和憲、三島健一
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07215
[Presentation] 中大脳動脈閉塞マウスを用いた脳梗塞遅延期におけるanti-HMGB1抗体の治療効果2022
- Author(s)
  田頭祐依、江頭早紀、森本麻友香、江口幸臣、中野貴文、入江圭一、細川雅人、山下郁太、佐野和憲、三島健一
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07215
[Presentation] 脳梗塞モデルマウスにおける血中タンパク質の動態2022
- Author(s)
  江頭早紀、中野貴文、田頭祐依、仲村佳彦、江口幸臣、亀谷富由樹、細川雅人、佐藤朝光、入江圭一、山下郁太、佐野和憲、三島健一
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07215
[Presentation] Dynamics of plasma Serine protease inhibitor A3N (Serpina3n) level following focal cerebral ischemia in mice2022
- Author(s)
  Saki Egashira, Hiroshi Kashiwagi, Minami Mori, Takafumi Nakano, Keichi Irie, Masato Hosokawa, Fuyuki Kametani, Yoshiriko Nakamura, Shunya Otsubo, Tomomitsu Satho, Yuta Yamashita, Kazunori Sano, Kenichi Mishima
- Organizer
  NEURO 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07215
[Presentation] 4)遊離ヘモグロビン吸着剤ハプトグロビンの脳梗塞慢性期治療薬への応用2020
- Author(s)
  森本麻友香, 中野貴文, 岡野志のぶ, 神崎愛, 入江圭一, 山下郁太, 佐野和憲, 江川孝, 三島健一
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08433
[Presentation] 5)脳梗塞後の脳内炎症反応に対するアンチトロンビンIIIの治療効果2020
- Author(s)
  中野貴文, 岡野志のぶ, 入江圭一, 森本麻友香, 山下郁太, 佐藤朝光, 仲村佳彦, 佐野和憲, 江川孝, 三島健一
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08433
[Presentation] 脳梗塞マウスにおけるロイシンリッチα 2 グリコプロテインの動態2019
- Author(s)
  神崎愛, 中野貴文, 山崎元貴, 岡野志のぶ, 入江圭一, 山下郁太, 明瀬孝之, 西上知佐, 佐藤朝光, 三島健司, 松尾宏一, 佐野和憲, 三島健一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08433
[Presentation] 白金系抗がん剤oxaliplatin 誘発性末梢神経障害ラットに対する大麻成分Δ9-tetrahydrocannabinol による治療効果2018
- Author(s)
  赤木麻里, 明瀬孝之, 入江圭一, 近藤布由美, 伊賀歩実, 山下郁太, 松尾宏一, 林稔展, 佐藤朝光, 土橋良太, 金城順英, 森本聡, 田中宏幸, 佐野和憲, 三島健一
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K08606
[Presentation] 大麻含有成分Δ9-tetrahydrocannabinolによるラット超音波発声への影響とカンナビノイド受容体の関与2017
- Author(s)
  明瀬孝之、入江圭一、山下郁太、土橋良太、金城順英、佐藤朝光、森本聡、田中宏幸、松山清、三島健一
- Organizer
  第34回　和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-15K08606
[Presentation] Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice2017
- Author(s)
  Yoshihiko Nakamura, Takafumi Nakano, Keiichi Irie, Kazunori Sano, Junichi Tanaka, Yuta Yamashita, Tomomitsu Satho, Koichi Matsuo, Masayuki Fujioka, Hiroyasu Ishikura, Kenichi Mishima
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08433
[Presentation] 脳梗塞時における酸化 LDL 誘発性炎症反応に対する thrombospondin-1 の役割2017
- Author(s)
  中野貴文、入江圭一、山下郁太、明瀬孝之、高瀬友美、佐藤朝光、松尾宏一、佐野和憲、本多健治、神村英利、三島健一
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] Effect of delayed treatment with ADAMTS13 on cerebral ischemic injury compared with tPAs2017
- Author(s)
  Takafumi Nakano, Keiichi Irie, Yuta Yamashita, Takayuki Myose, Kazunori Sano, Yoshihiko Nakamura, Tomomitsu Satho, Mamiko Kai, Koji Tominaga, Hidetoshi Kamimura, Kenichi Mishima, Takashi Egawa
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08433
[Presentation] 長時間脳虚血マウスに対する血栓溶解薬 t-PA と DIC 治療薬 thrombomodulin の有用性2017
- Author(s)
  安村真子、中野貴文、仲村佳彦、入江圭一、山下郁太、明瀬孝之、佐藤朝光、三島健司、松尾宏一、佐野和憲、本多健治、石倉宏恭、三島健一
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] Effect of delayed treatment with ADAMTS13 on cerebral ischemic injury compared with tPAs2017
- Author(s)
  Takafumi Nakano, Keiichi Irie, Yuta Yamashita, Takayuki Myose, Kazunori Sano, Yoshihiko Nakamura, Tomomitsu Satho, Mamiko Kai, Koji Tominaga, Hidetoshi Kamimura, Kenichi Mishima, Takashi Egawa
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] Neuroprotective Effects of ADAMTS13 against Delayed Brain Ischemia after Aneurysmal Subarachnoid Hemorrhage2017
- Author(s)
  Fujioka M, Muroi C, Tsuboi A, Okuchi K, Nakase H, Abe K, Mishima K
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] ADAMTS 13 - Microthrombosis in Subarachnoid Hemorrhage - an Update -2017
- Author(s)
  Muroi C, Fujioka M, Abe K, Keller E, Fujimura Y, Mishima K
- Organizer
  Vasospasm 2017. The 14th International Conference on Neurovascular Events after Subarachnoid Hemorrhage
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice2017
- Author(s)
  Yoshihiko Nakamura, Takafumi Nakano, Keiichi Irie, Kazunori Sano, Junichi Tanaka, Yuta Yamashita, Tomomitsu Satho, Koichi Matsuo, Masayuki Fujioka, Hiroyasu Ishikura, Kenichi Mishima
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] クモ膜下出血後の脳虚血に対するADAMTS13の神経保護効果2016
- Author(s)
  藤岡政行, 室井カール, 坪井昭夫, 奥地一夫, 中瀬裕之, 阿部浩司, 三島健一
- Organizer
  第7５回日本脳神経外科学会学術総会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] 大麻活性成分Δ9-tetrahydrocannabinolが生体外刺激に対するラットの情動反応に与える影響2016
- Author(s)
  明瀬孝之、入江圭一、山下郁太、中嶋亜梨紗、田中まりの、土橋良太、金城順英、佐藤朝光、佐野和憲、本多健治、森元聡、田中宏幸、松山清、三島健一
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-15K08606
[Presentation] Δ9-Tetrahydrocannabinol とMethamphetamine が誘発するラットの超音波発声の比較2016
- Author(s)
  明瀬孝之, 入江　圭一, 山下郁太, 寺前祐樹, 平野真梨, 中嶋亜梨紗, 田中まりの, 土橋良太, 金城順英, 佐藤朝光, 佐野和憲, 本多健治, 三島健一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08606
[Presentation] 脳虚血およびクモ膜下出血後の遅発性脳虚血病態に対するADAMTS13の脳保護機能2015
- Author(s)
  藤岡政行, 室井カール, 松山武, 阿部浩司、三島健一
- Organizer
  第40回日本脳卒中学会総会
- Place of Presentation
  リーガロイヤルホテル広島　広島
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] Filament Perforation Model for Mouse Subarachnoid Hemorrhage: Evaluation by 7.0T MRI2015
- Author(s)
  Carl Muroi, Yuto Kashiwagi, Takemi Rokugawa, Misato Tonomura, Atsushi Obata, Edin Nevzati, Akio Tsuboi, Kenichi Mishima, Kohji Abe, Masayuki Fujioka.
- Organizer
  Vasospasm 2015. 13th International Conference on Neuromuscular Events after Subarachnoid Hemorrhage
- Place of Presentation
  Karuizawa Prince Hotel West, Karuizawa
- Year and Date
  2015-09-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] 脳動脈瘤破裂クモ膜下出血後の脳虚血病態に対するADAMTS13の脳保護機能.2015
- Author(s)
  藤岡政行, 室井カール, 奥地一夫, 中瀬裕之, 阿部浩司, 三島健一.
- Organizer
  第74回日本脳神経外科学会学術総会
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] 脳梗塞における多機能サイトカインであるOncostatin M受容体の発現変化2014
- Author(s)
  大石悠加, 入江圭一, 中野貴文, 楢崎友里, 田中雅彬, 佐藤朝光, 二神幸次郎, 三島健一, 岩崎克典
- Organizer
  第134回年会日本薬学会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 脳梗塞における多機能サイトカインであるOncostatin M受容体の発現変化2014
- Author(s)
  大石悠加、入江圭一、中野貴文、楢崎友里、田中雅彬、佐藤朝光、二神幸次郎、三島健一、岩崎克典
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 虚血‐再潅流およびクモ膜下出血後の脳虚血病態に対するADAMTS13の脳保護機能2014
- Author(s)
  藤岡政行, 室井カール, 松山武, 三島健一
- Organizer
  第７３回日本脳神経外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪　東京
- Year and Date
  2014-10-09
- Data Source
  KAKENHI-PROJECT-26462170
[Presentation] Involvement of trombospondin 1 on cerebroprotective effect of ADAMTS13 in ischemic injury after transient focal cerebral ischemia2014
- Author(s)
  Masayoshi Tanaka, Keiichi Irie, Takafumi Nakano, Kaori Kubota, Shutaro Katsurabayashi, Kotaro Takasaki, Koujirou Futagami, Kenichi Mishima, Katsunori Iwasaki
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 新生児低酸素性虚血性脳症モデルラットの脳損傷に対する内因性カンナビノイドを介したデキサメタゾンの脳保護作用2013
- Author(s)
  宮澤秋子, 坂元佑哉, 入江圭一, 三島健一, 宮崎蓉子, 栫千恵, 中村裕司, 窪田香織, 桂林秀太郎, 高崎浩太郎, 岩崎克典, 藤原道弘
- Organizer
  第133回年会日本薬学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] ADAMTS13: A Novel Therapeutic Drug Candidate for Acute and for Delayed Brain Ischemia2013
- Author(s)
  Fujioka M., Muroi C., Mishima K., Fujiwara M., Okuchi K., Siesjo B.K
- Organizer
  57th Annual Meeting of Thrombosis and Haemostasis Research
- Place of Presentation
  Munich, Germany
- Year and Date
  2013-02-23
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 脳虚血障害に対する血液凝固制御因子ADAMTS13の脳保護作用におけるtrombospondin 1の関与2013
- Author(s)
  田中雅彬, 入江圭一, 中野貴文, 窪田香織, 桂林秀太郎, 高崎浩太郎, 二神幸次郎, 三島健一, 岩崎克典
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 長時間脳虚血モデルマウスに対する血液凝固制御因子ADAMTS13の脳保護効果-新規血栓溶解薬への応用-2013
- Author(s)
  中野貴文, 田中雅彬, 入江圭一, 仲村佳彦, 石倉宏恭, 二神幸次郎, 三島健一, 岩崎克典
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2013-11-16
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] ADAMTS13: A Novel Therapeutic Drug Candidate for Acute Ischemic Stroke2012
- Author(s)
  Masayuki Fujioka, Kazuhide Hayakawa, Carl Muroi, Keiichi Irie, Kenichi Mishima, Yoshihiro Fujimura, Michihiro Fujiwara, Kazuo Okuchi, Bo K. Siesjo
- Organizer
  Asia Pacific Stroke Conference 2012
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2012-09-10
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] Intravenous administration of human CD34+ cord blood cells after neonatal stroke ameliorates brain damage in a mouse model.2012
- Author(s)
  Masahiro Tsuji, Akihiko Taguchi, Yukiko Kasahara, Makiko Ohshima, Kenichi Yamahara, Tomohiro Matsuyama, Tomoaki Ikeda.
- Organizer
  The 8th Hershey Conference on Developmental Brain Injury
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-24591617
[Presentation] ADAMTS13:急性脳虚血に対する治療応用の可能性2012
- Author(s)
  藤岡政行, Muroi Carl, 三島健一, 藤村吉博, 奥地一夫, 藤原道弘, Siesjo Bo
- Organizer
  第71回日本脳神経外科学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 新生児低酸素性虚血性脳症モデルラットにおけるドーパミン神経障害誘発性回転行動に対する脳血管新生病変形成の関与2012
- Author(s)
  坂元佑哉, 入江圭一, 三島健一, 秋武義治, 宮澤秋子, 栫千恵, 中村裕司, 窪田香織, 桂林秀太郎, 高崎浩太郎, 岩崎克典, 藤原道弘
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 脳梗塞モデルマウスを用いたプログラニュリンの発現変化とミクログリアの活性化に関する研究2012
- Author(s)
  古川歩, 入江圭一, 三島健一, 高崎浩太郎, 桂林秀太郎, 窪田香織, 岩崎克典, 藤原道弘
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 新生児低酸素性虚血性脳症モデルラットにおける脳損傷に対するドパミン神経系の関与2011
- Author(s)
  坂元佑哉, 秋武義治, 入江圭一, 宮﨑蓉子, 栫千恵, 中村裕司, 窪田香織, 桂林秀太郎, 高崎浩太郎, 三島健一, 岩崎克典, 藤原道弘
- Organizer
  第39回薬物活性シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 新生児低酸素性虚血性脳症モデルラットにおける虚血同側への異常な回転行動に対するドーパミン神経系の関与2010
- Author(s)
  坂元佑哉、三島健一、秋武義治、入江圭一、宮崎蓉子、栫千恵、窪田香織、桂林秀太郎、高崎浩太郎、岩崎克典、藤原道弘
- Organizer
  第63回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] 新生児低酸素性虚血性脳症(HIE)モデルラットの緩徐進行性脳損傷に対するアストロサイトに発現したカンナビノイド受容体の関与2010
- Author(s)
  宮崎蓉子、坂元佑哉、石兼真、原田和彦、入江圭一、池田智明、松山清、三島健司、桂林秀太郎、高崎浩太郎、三島健一、岩崎克典、藤原道弘
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] 低酸素性虚血により生じる緩徐進行性脳損傷の性差の発現には活性化アストロサイトが関与している2010
- Author(s)
  坂元佑哉、石兼真、原田和彦、三島健一、入江圭一、樋口聖、白川敦規、宮崎蓉子、池田智明、桂林秀太郎、高崎浩太郎、岩崎克典、藤原道弘
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] 繰り返し能虚血ラットの空間記憶障害と海馬のアポトーシスに対するPPARγ活性化薬の作用2010
- Author(s)
  内田佳菜子、岩崎克典、原口珠実、高崎浩太郎、白井友紀子、鬼村理香、進藤太郎、内田直樹、窪田香織、桂林秀太郎、三島健一、西村良二、藤原道弘
- Organizer
  第40回日本神経精神薬理学会年会
- Place of Presentation
  仙台市
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21590298
[Presentation] 下肢虚血モデルラットを用いた卵膜由来間葉系幹細胞の他家細胞移植による血管新生効果の検討2009
- Author(s)
  石兼真、池田智明、原田和彦、三島健一、岩崎克典、藤原道弘
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] Ovarievctomy gets worse the brain damage and learning impairment by hypoxic-ischemia in neonatal rats2009
- Author(s)
  Y.Sakamoto, S.Ishikane, K.Harada, K.Mishima, K.Irie, T.Nakashima, S.Higuchi, A.Shirakawa, Y.Miyazaki, T.Ikeda, S.Katsurabayashi, T.Takasaki, K.Iwasaki, M.Fujiwara
- Organizer
  Neuroscience
- Place of Presentation
  Chicago,USA
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] 下肢虚血モデルに対するヒト卵膜由来間葉系幹細胞移植による血管新生効果2009
- Author(s)
  原田和彦、大西俊介、山原研一、佐田正晴、石兼真、大谷健太郎、中村篤宏、三島健一、岩崎克典、藤原道弘、寒川賢治、北村惣一郎、永谷憲歳、池田智明
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] Therapeutic Angiogenesis by Transplantation of Allogeneic Fetal Membrane-Derived Mesenchymal Stem Cells2009
- Author(s)
  Ishikane S, Nagaya N, Yamahara K, Sada M, Harada K, Mishima K, Iwasaki K, Fujiwara M, Ikeda T
- Organizer
  American College of Cardiology 58th Annual Scientific Session
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] Implantation of encapsulated glial cell line-derived neurotrophic factor-secreting cells prevents long-lasting learning impairment following neonatal hypoxic-ischemic brain insult in rats2008
- Author(s)
  Katsuragi S, Ikeda T, Date I, Shingo T, Yasuhara T, Mishima K, Aoo N, Harada K, Egashira N, Iwasaki K, Fujiwara M, Ikenoue T
- Organizer
  6th Hershey Conference
- Place of Presentation
  Harrisburg, USA
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] Therapeutic potential of mesenchymal stem cells derived from three different layers of human fetal membrane in hindlimb ischemia model2008
- Author(s)
  Harada K, Ohnishi S, Yamahara K, Sada M, Ishikane S, Mishima K, Iwasaki K, Fujiwara M, Kangawa K, Kitamura S, Nagaya N, Ikeda T
- Organizer
  American Heart Association Scientific Session
- Place of Presentation
  New Orleans, USA
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] Abnormal turning behavior but not ultrasonic vocalization correlates with hypoxic-ischemic brain injury in neonatal rats2008
- Author(s)
  Harada K, Mishima K, Iwasaki K, Fujiwara M, Nagaya N, Iwasaki K, Fujiwara M
- Organizer
  6th Hershey Conference
- Place of Presentation
  Harrisburg, USA
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-20590552
[Presentation] Involvement of insulin resistance and leaming and memory disturbances in ananimal model of Alzheimer's disease2007
- Author(s)
  Shimizu Y, Iwasaki K, Ishikane S, Takasaki K, Watanabe T, Egashira N, Mishima K, and Fujiwara M
- Organizer
  37th ANNUAL MEETING SOCIETY FOR NEUROSCIENCE
- Place of Presentation
  San Diego,USA
- Data Source
  KAKENHI-PROJECT-19590545
[Presentation] Involvement of brain insulin resistance and learning and memory disturbances in an animal model of Alzheimer's Disease2007
- Author(s)
  Yoshika Shimizu, Katsunori Iwasaki, Shin Ishikane, Kotaro Tkasaki, Takuya Watanabe, Nobuaki Egashira, Kenichi Mishima, Michihiro Fujiwara
- Organizer
  37th ANNUAL MEETING SOCIETY FOR NEUROSCIENCE
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-19590545
[Presentation] 新生児低酸素性虚血性脳症モデルラットにおけるドーパミン神経障害誘発性回転行動に対する脳血管新生病変形成の関与
- Author(s)
  坂元佑哉、入江圭一、三島健一、秋武義治、宮澤秋子、栫千恵、中村裕司、窪田香織、桂林秀太郎、高崎浩太郎、岩崎克典、藤原道弘
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590654
[Presentation] 大麻によって発現する動物の異常行動
- Author(s)
  三島健一
- Organizer
  第26回(平成24年度)薬物依存臨床医師研修会・第14回(平成24年度)薬物依存臨床看護等研修会
- Place of Presentation
  国立精神・神経医療研究センター
- Invited
- Data Source
  KAKENHI-PROJECT-23591685
[Presentation] 大麻によって発現する動物の異常行動
- Author(s)
  三島健一、藤原道弘
- Organizer
  第25回(平成23年度)薬物依存臨床医師研修会・第13回(平成23年度)薬物依存臨床看護等研修会(招待講演)
- Place of Presentation
  国立精神・神経センター
- Data Source
  KAKENHI-PROJECT-23591685

1. FUJIWARA Michihiro (10091331)

# of Collaborated Projects: 9 results

# of Collaborated Products: 79 results
2. IWASAKI Katsunori (10183196)

# of Collaborated Projects: 8 results

# of Collaborated Products: 66 results
3. IRIE Keiichi (50509669)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
4. EGASHIRA Nobuaki (80352269)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
5. 佐野和憲 (50534343)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
6. 佐藤朝光 (90369025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
7. NISHIMURA Ryoji (10122722)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 仲村佳彦 (20632201)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
9. 中野貴文 (40804539)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
10. INOKUCHI Jin-ichi (70131810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIGEMATSU Mikiji (00242743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OHGA Shoji (60117075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MASAMOTO Hiroshi (30122740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAMEI Ichiro (90526526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKASAKI Kotaro (70461506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. KATSURABAYASHI Shutaro (50435145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
17. TSUJI MASAHIRO (80579467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. TAGUCHI Akihiko (10359276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. YAMAHARA Kenichi (50450888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. IIDA Hidehiro (30322720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ENMI Junichiro (80393205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MATSUYAMA Tomohiro (10219529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. HAYAKAWA Masahiro (40343206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SATO Yoshiaki (30435862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Fujioka Masayuki (20254518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
26. TAOKA Toshiaki (30305734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ABE Kohji (80571207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
28. NAKASE Hiroyuki (10217739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. TAKANO Yukio (50113246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
30. SAITO Ryo (80122696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. HONDA Kenji (60140761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. IKEDA Tomoaki (80202894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
33. 細川雅人 (00435116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
34. 山下郁太 (90823964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
35. MUROI Carl, Izumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
36. FUJIMURA Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
37. TSUBOI Akio

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
38. KOZAKO Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 松山知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mishima Kenichi 三島 健一

MISHIMA Kenichi 三島 健一

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The effect of meal content on emotional behavior: role of cannabinoid receptorPrincipal Investigator

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A possible neuroprotective role of ADAMTS13 by ameliorating post-ischemic hypoperfusionPrincipal Investigator

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Study for regeneration of function in neonatal hypoxic-ischemic encephalopathy using animal model of slowly progressive brain damage in ratsPrincipal Investigator

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Investigation of cerebral paralysis and its development of new drugs in neonatal hypoxic-ischemia-induced slowly progressive brain damagePrincipal Investigator

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Mishima Kenichi 三島健一

MISHIMA Kenichi 三島健一

[Journal Article] 脳梗塞モデルマウスに対する播種性血管内凝固症候群治療薬トロンボモデュリンアルファの効果2017