FUJITA MIKAKO 藤田美歌子

… Alternative Names

FUJITA Mikako 藤田美歌子

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Researcher Number	00322256
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(薬), 特任教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 熊本大学, 大学院生命科学研究部(薬), 特任教授 2018: 熊本大学, 生命科学研究部, 特任教授 2017: 熊本大学, 薬学部, 准教授 2016 – 2017: 熊本大学, 薬学部附属創薬研究センター, 准教授 2013 – 2015: 熊本大学, 薬学部, 准教授 … More 2011: 熊本大学, 薬学部附属創薬研究センター, 准教授 2009 – 2011: Kumamoto University, 薬学部, 准教授 2007 – 2008: Kumamoto University, 大学院・医学薬学研究部, 准教授 2005: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 助手 2004 – 2005: The University of Tokushima, Graduate School Institute of Health Biosciences, Assistant Professor, 大学院・ヘルスバイオサイエンス研究部, 助手 2002 – 2003: 徳島大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Virology / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Drug development chemistry / Virology / Biological Sciences / Basic Section 42020:Veterinary medical science-related / Basic Section 56010:Neurosurgery-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator HIV / HIV-1 / ウイルス / Gag / HIV根絶 / IP6 / X線結晶解析 / プロドラッグ体 / アポトーシス / イノシトールリン脂質 … More / Cullin / Vif / 感染症 / マクロファージ / アクセサリー蛋白質 / HIV-2 / Vpx / 蛋白質 / MA / タンパク質発現 / Gag MAドメイン / HIV Gagタンパク質 / HIV潜伏感染細胞 / エイズ完全治癒 / MAドメイン / Gagタンパク質 / 完全治癒 / プロドラッグ / エイズ根絶 / ALS / ヘテロ環化合物 / トリテルペン / ボスチニブ / ダサチニブ / ハイブリッド分子 / c-Abl阻害剤 / エダラボン / 筋委縮性側索硬化症(ALS) / 脂質 / 薬学 / 細胞内導入キャリア / DSFアッセイ / HIV放出抑制 / X線構造解析 / エイズ根治 / 誘導体 / フィチン酸 / 潜伏感染細胞 / エイズ完治 / lysine / ubiquitination / viral replication / proteasome degradation / accessory protein / アルギニン / リジン / ユビキチン化 / ウイルス複製 / プロテアソーム分解 / 変異体 / 蛋白質分解 / 蛋白質発現 / 蛋白質安定性 / ポリプロリン / 亜鉛フィンガー / ポリプロリンモチーフ / 変異体解析 / 抗ウイルス宿主因子 / SAMHD1 / THP-1 / PMA / 抗HIV宿主因子 / 逆転写反応 / FLAG / BIACore / Gag(p17) / PLCδ_1 PH / Biacore / Vpu / NC / イノシトールリン酸 / エイズ … More Except Principal Investigator HIV-1 / Vif / Vpr / Vpx / HIV-2 / プロテアソーム分解 / Nef / 脳保護 / Vpu / HSIV / Lock-in and Apoptosis / PI(4,5)P2 類縁体 / イノシトールリン脂質 / FIV / ネコ免疫不全ウイルス / 神経線維腫症 / interactome / proteomics / NF2 / NF1 / neurofibromatosis / ナファモスタット / ADAM17 / TGF-b/Smad / COVID-19 / 感染阻止 / TMPRSS2 / COVID19 / 薬学 / 脳神経疾患 / HNE / 脳保護薬 / scyllo-イノシトール / 亜鉛キレーター / アミロイドβ / アルツハイマー病 / proteasome-degradation / ルシフェラーゼ / SIV / X線結晶構造解析 / ラクタム剤 / 阻害剤 / Ｘ線結晶構造解析 / 抗生物質 / ラクタマーゼ / 感染症 / TGF-β/Smad経路 / TGF-b/Smad 経路 / PI3K/Akt 経路 / TGF-b/Smad経路 / PI3K/Akt経路 / 強皮症 / 癌 / ＴＧＦ‐β／Ｓｍａｄ経路 / ＰＩ３Ｋ／Ａｋｔ経路 / NF-κB / APOBEC3G / 抗エイズ薬 / 細胞毒性 / 種特異性 / Gag / SIVmac Less

Development of a new fundamental treatment for feline immunodeficiency virus (FIV) infection
- Principal Investigator
  
  大杉剛生
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kumamoto University
Development of edaravone-c-Abl inhibitor hybrids as next generation ALS therapeuticsPrincipal Investigator
- Principal Investigator
  
  藤田美歌子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kumamoto University
Development of therapeutic drugs that tandemly suppress infection, lung fibrosis, and malignant transformation of the new coronavirus
- Principal Investigator
  
  Otsuka Masami
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kumamoto University
Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of therapeutic strategies
- Principal Investigator
  
  荒木令江
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kumamoto University
Structure optimization of compounds to confine HIV in a cell and induce apoptosis aiming at drugsPrincipal Investigator
- Principal Investigator
  
  Fujita Mikako
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kumamoto University
Development of a method to induce apoptosis by HIV locked in a cellPrincipal Investigator
- Principal Investigator
  
  Fujita Mikako
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Development of a novel brain protectant
- Principal Investigator
  
  Otsuka Masami
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
Development of inhibitors based on the molecular structure and mechanism of substrate hydrolysis by metallo-beta-lactamases
- Principal Investigator
  
  KUROSAKI Hiromasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kinjo Gakuin University
  Kumamoto University
Design and synthesis of a compound targeting amyloid beta aiming at the cure of Alzheimer's disease
- Principal Investigator
  
  Otsuka Masami
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
Elucidation of SAMHD1-independent function of HIV/SIV VpxPrincipal Investigator
- Principal Investigator
  
  Fujita Mikako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Development of medicinal molecules having biologically functions targeting the PI3K/Akt pathway and the TGF-b/Smad pathway
- Principal Investigator
  
  OTSUKA Masami
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
Design and synthesis of anti-HIV agents that inhibit the Vif-mediated proteasome degradation of APOBEC3G
- Principal Investigator
  
  OTSUKA Masami
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
Identification and functional analysis of anti-HIV host factor in macrophagesPrincipal Investigator
- Principal Investigator
  
  FUJITA Mikako
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Regulation of HIV replication by inositol phosphatesPrincipal Investigator
- Principal Investigator
  
  FUJITA Mikako
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
HIVの複製・病原性発現に必須なアクセサリー蛋白質の系統的構造・機能相関解析
- Principal Investigator
  
  足立昭夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Regulation of HIV replication by proteasome degradation of VifPrincipal Investigator
- Principal Investigator
  
  FUJITA Mikako
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokushima
HIV病原性解析のための新規感染実験システムの確立
- Principal Investigator
  
  ADACHI Akio
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
HIV/SIV Gagハイブリッドウイルスの作製とその解析
- Principal Investigator
  
  足立昭夫
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  The University of Tokushima
Functional domain analysis of HIV accessory proteins
- Principal Investigator
  
  ADACHI Akio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokushima

[Book] Design and Synthesis of Biotinylated Inositol Phosphates: Application to the Inositol Phosphate-Protein Binding Analysis2013
- Author(s)
  Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
- Total Pages
  10
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-23390028
[Book] Design and Synthesis of Biotinylated Inositol Phosphates : Application to the Inositol Phosphate-Protein Binding Analysis. "Inositol" (Ed. By Rochha H, Cardoso M)2013
- Author(s)
  Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-23390028
[Journal Article] Structure and dynamics of the ABL1 tyrosine kinase and its important role in chronic myeloid leukemia2025
- Author(s)
  Irgit A, Kamis R, Sever B, Tuyun AF, Otsuka M, Fujita M, Demirci H, and Ciftci H
- Journal Title
  
  Archiv der Pharmazie
  
  Volume: 358 Issue: 5
- DOI
  10.1002/ardp.70005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KF0270
[Journal Article] Ligand-based design and synthesis of new trityl histamine and trityl cysteamine derivatives as SIRT2 inhibitors for cancer therapy2024
- Author(s)
  Badran Mostafa M.、Abbas Samar H.、Tateishi Hiroshi、Maemoto Yuki、Toma Tsugumasa、Ito Akihiro、Fujita Mikako、Otsuka Masami、Abdel-Aziz Mohamed、Radwan Mohamed O.
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 269 Pages: 116302-116302
- DOI
  10.1016/j.ejmech.2024.116302
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ1769, KAKENHI-PROJECT-23H05473, KAKENHI-PROJECT-20H03365
[Journal Article] A review of FDA-approved anti-HIV-1 drugs, anti-Gag compounds, and potential strategies for HIV-1 eradication2024
- Author(s)
  Sever B, Otsuka M, Fujita M, and Ciftci H
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 7 Pages: 3659-3659
- DOI
  10.3390/ijms25073659
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KF0270
[Journal Article] An ADAM17 selective inhibitor promotes glucose uptake by activating AMPK2024
- Author(s)
  Toma Tsugumasa、Miyakawa Nobukazu、Tateishi Mika、Todaka Mikio、Kondo Tatsuya、Fujita Mikako、Otsuka Masami、Araki Eiichi、Tateishi Hiroshi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 1 Pages: 37-46
- DOI
  10.1016/j.jphs.2023.11.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1769, KAKENHI-PROJECT-21K08533, KAKENHI-PROJECT-20H03365
[Journal Article] Harnessing pyrimidine as a building block for HDAC inhibitors2023
- Author(s)
  Badran, M.M., Abbas, S.H., Fujita, M., and Abdel-Aziz, M.
- Journal Title
  
  Archiv der Pharmazie
  
  Volume: 356 Issue: 10
- DOI
  10.1002/ardp.202300208
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] The unique activity of saponin: Induction of cytotoxicity in HTLV-1 infected cells2023
- Author(s)
  Shida Wataru、Tahara Yurika、Morikawa Saki、Monde Kazuaki、Koga Ryoko、Ohsugi Takeo、Otsuka Masami、Ikemoto Atsushi、Tateishi Hiroshi、Ikeda Tsuyoshi、Fujita Mikako
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 91 Pages: 117408-117408
- DOI
  10.1016/j.bmc.2023.117408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K02133, KAKENHI-PROJECT-20K07122, KAKENHI-PROJECT-20H03365
[Journal Article] Design, synthesis, in vitro and in silico characterization of plastoquinone analogs containing piperidine moiety as antimicrobial agents2023
- Author(s)
  Yildiz, M., Yildirim, H., Bayrak, N., Cakmak, S.M., Mataraci-Kara, E., Ozbek-Celik, B., Otsuka, M., Fujita, M., Radwan, M.O., and Tuyun, A.F.
- Journal Title
  
  Journal of Molecular Structure
  
  Volume: 1277 Pages: 134845-134845
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] HIV-1 Gag MA domain binds to cardiolipin in a binding mode distinct from virus assemble mediator PI(4,5)P22023
- Author(s)
  Tateishi, H., Chinen, T., Fukuda, R., Radwan, M.O., Shimagaki, K., Koga, R., Masuda, T., Okamoto, Y., Sakamoto, A., Misumi, S., Otsuka, M., Fujita, M., and Anraku, K.
- Journal Title
  
  Chemical Biology & Drug Design
  
  Volume: 103 Issue: 1
- DOI
  10.1111/cbdd.14401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Turkish Plants, Including Quercetin and Oenothein B, Inhibit the HIV-1 Release and Accelerate Cell Apoptosis2023
- Author(s)
  Tahara Y, Fujita M, Zhang T, Wang D, Tateishi T, Togami A, Nyame P, Terasawa H, Monde N, Appiah-Kubi J, Ofotsu Amesimeku W, Alsaadi DHM, Wada M, Sugimura K, Gezici S, Ciftci H, Karahan F, Sekeroglu N, Otsuka M, Sawa T, Maeda Y, Watanabe T, Monde K
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 11 Pages: 1535-1547
- DOI
  10.1248/bpb.b23-00328
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-11-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08602, KAKENHI-PROJECT-20H03365
[Journal Article] Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish Light Source “Turkish DeLight”2023
- Author(s)
  Atalay, N., Akcan, E.K., Gul, M., et al. (Fujita Mは47人中38番目)
- Journal Title
  
  Turkish Journal of Biology
  
  Volume: 47 Issue: 1 Pages: 1-13
- DOI
  10.55730/1300-0152.2637
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Harnessing oleanolic acid and its derivatives as modulators of metabolic nuclear receptors2023
- Author(s)
  Radwan, M.O., Kadasah, S.F., Aljubiri, S.M., Alrefaei, A.F., El-Maghrabey, M.H., El Hamd, M.A., Tateishi, H., Otsuka, M., and Fujita, M.
- Journal Title
  
  Biomolecules
  
  Volume: 13 Issue: 10 Pages: 1465-1465
- DOI
  10.3390/biom13101465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Rapid and Efficient Ambient Temperature X-ray Crystal Structure Determination at Turkish Light Source2023
- Author(s)
  Glu, M., Ayan, E, Destan, E., et al. (Fujita Mは37人中29番目)
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 8123-8123
- DOI
  10.1038/s41598-023-33989-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] New insight into the bioactivity of substituted benzimidazole derivatives: Repurposing from anti-HIV activity to cell migration inhibition targeting hnRNP M2023
- Author(s)
  Radwan Mohamed O.、Toma Tsugumasa、Arakaki Yuiichi、Kamo Masahiro、Inoue Naoya、Koga Ryoko、Otsuka Masami、Tateishi Hiroshi、Fujita Mikako
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 86 Pages: 117294-117294
- DOI
  10.1016/j.bmc.2023.117294
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ1769, KAKENHI-PROJECT-20H03365
[Journal Article] Structural Characterization of Zinc(II)/Cobalt(II) Complexes of Chiral N-(Anthracen-9-yl)methyl-N,N-bis(2-picolyl)amine and Evaluation of DNA Photocleavage Activity2023
- Author(s)
 Ichimaru Yoshimi、Kato Koichi、Nakatani Rina、Isomura Risa、Sugiura Kirara、Yamaguchi Yoshihiro、Jin Wanchun、Mizutani Hideki、Imai Masanori、Kurihara Masaaki、Fujita Mikako、Otsuka Masami、Kurosaki Hiromasa
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 71 Issue: 7 Pages: 545-551
- DOI
 10.1248/cpb.c23-00043
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2023-07-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K15244, KAKENHI-PROJECT-23K06291, KAKENHI-PROJECT-20K07210, KAKENHI-PROJECT-20H03365
[Journal Article] Gypsogenin battling for a front position in the pentacyclic triterpenes game of thrones on anti-cancer therapy: A critical review―Dedicated to the memory of professor Hanaa M. Rady2023
- Author(s)
  Radwan, M.O., Abd-Alla, H.I., Alsaggaf, A.T., El-Mezayen, H., Abourehab, M.A.S., El-Beeh, M.E., Tateishi, H., Otsuka, M., and Fujita, M.
- Journal Title
  
  Molecules
  
  Volume: 28 Issue: 15 Pages: 5677-5677
- DOI
  10.3390/molecules28155677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Structural characterization of TRAF6 N-terminal for therapeutic uses and computational studies on new derivatives2023
- Author(s)
  Guven O, Sever B, Basoglu-Unal F, Ece A, Tateishi H, Koga R, Radwan MO, Demir N, Can M, Aytemir M, Inoue J, Otsuka M, Fujita M, Ciftci H, and DeMirci H
- Journal Title
  
  Pharmaceuticals
  
  Volume: 16 Issue: 11 Pages: 1608-1608
- DOI
  10.3390/ph16111608
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KF0270, KAKENHI-PROJECT-20H03365
[Journal Article] Scaffold hopping and structural modification of NSC 663284: Discovery of potent (non)halogenated aminobenzoquinones2023
- Author(s)
  Bayrak N, Sever B, Ciftci H, Otsuka M, Fujita M, and Tuyun AF
- Journal Title
  
  Biomedicines
  
  Volume: 12 Issue: 1 Pages: 50-50
- DOI
  10.3390/biomedicines12010050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KF0270, KAKENHI-PROJECT-20H03365
[Journal Article] Tranilast-tyrosine hybrid molecule exhibits dual activity: suppression of epithelial-mesenchymal transition and induction of cytotoxicity in cancer cells2022
- Author(s)
  Toma, T., Yamashita, J., Radwan, M.O., Badran, M.M., Masunaga, T., Kamo, M., Koga, R., Okamoto, Y., Tateishi, H., Otsuka., M., and Fujita, M.
- Journal Title
  
  Medicinal Chemistry Research
  
  Volume: 31 Issue: 9 Pages: 1584-1593
- DOI
  10.1007/s00044-022-02939-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Discovery of azaindolin-2-one as a dual inhibitor of GSK3β and tau aggregation with potential neuroprotective activity2022
- Author(s)
  Ali, T.F.S., Ciftci, H.I., Radwan, M.O., Roshdy, E., Shawky, A.M., Abourehab, M.A.S., Tateishi, H., Otsuka, M., and Fujita, M.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 4 Pages: 426-426
- DOI
  10.3390/ph15040426
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Novel inhibitor for downstream targeting of transforming growth factor-beta signaling to suppress epithelial to mesenchymal transition and cell migration2022
- Author(s)
  Toma, T., Tateishi, H., Kawakami, K., Ali, T.F.S., Kamo, M., Monde, K., Nakashima, Y., Fujita, M., and Otsuka, M.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 9 Pages: 5047-5047
- DOI
  10.3390/ijms23095047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Natural-product-inspired design and synthesis of thiolated coenzyme Q analogs as promising agents against Gram-positive bacterial strains: insights into structure-activity relationship, activity profile, mode of action, and molecular docking2022
- Author(s)
  Yildirim, H., Yildiz, M., Bayrak, N., Mataraci-Kara, E., Ozbek-Celik, B., Otsuka, M., Fujita, M., Radwan, M.O., and Tuyun, A.F.
- Journal Title
  
  RSC Advances
  
  Volume: 12 Issue: 32 Pages: 20507-20518
- DOI
  10.1039/d2ra02136f
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Comprehensive research on past and future therapeutic strategies devoted to treatment of amyotrophic lateral sclerosis2022
- Author(s)
  Sever, B., Ciftci, H., DeMirci, H., Sever, H., Ocak, F., Yulug, B., Tateishi, H., Tateishi, T., Otsuka, M., Fujita, M., and Basak, N.A.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 5 Pages: 2400-2400
- DOI
  10.3390/ijms23052400
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-β-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution2022
- Author(s)
  Yamaguchi Yoshihiro、Kato Koichi、Ichimaru Yoshimi、Uenosono Yuya、Tawara Sakiko、Ito Rio、Matsuse Natsuki、Wachino Jun-ichi、Toma-Fukai Sachiko、Jin Wanchun、Arakawa Yoshichika、Otsuka Masami、Fujita Mikako、Fukuishi Nobuyuki、Sugiura Kirara、Imai Masanori、Kurosaki Hiromasa
- Journal Title
  
  ACS Infectious Diseases
  
  Volume: 9 Issue: 1 Pages: 65-78
- DOI
  10.1021/acsinfecdis.2c00395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06500, KAKENHI-PROJECT-21K15244, KAKENHI-PROJECT-21H02967, KAKENHI-PROJECT-17K08376, KAKENHI-PROJECT-20H03365
[Journal Article] Promising antibacterial and antifungal agents based on thiolated vitamin K3 analogs: Synthesis, bioevaluation, molecular docking2022
- Author(s)
  Yildirim, H., Yildiz, M., Bayrak, N., Mataraci-Kara, E., Radwan, M.O., Jannuzzi, A.T., Otsuka, M., Fujita, M., and Tuyun, A.F.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 5 Pages: 586-586
- DOI
  10.3390/ph15050586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Studies on 1,4-quinone derivatives exhibiting anti-leukemic activity along with anti-colorectal and anti-breast cancer effects2022
- Author(s)
  Ciftci, H., Sever, B., Kaya, N., Bayrak, N., Yildiz, M., Yildirim, H., Tateishi, H., Otsuka, M., Fujita, M., and Tuyun, A.F.
- Journal Title
  
  Molecules
  
  Volume: 28 Issue: 1 Pages: 77-77
- DOI
  10.3390/molecules28010077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] New insights into the structural requirements of isatin-derived pro-apoptotic agents against acute myeloid leukemia2022
- Author(s)
  Hamdy, A.K., Sakamoto, T., Toma, T., Sakamoto, M., Abourehab, M.A.S., Otsuka, M., Fujita, M., Tateishi, H., and Radwan, M.O.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 12 Pages: 1579-1579
- DOI
  10.3390/ph15121579
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction2022
- Author(s)
  Ulusoy, N.G., Emirdag, S., Sozer, E., Radwan, M.O., Ciftci, H., Aksel, M., Bolukbasi, S.S., Ozmen, A., Yayli, N., Karayildirim, T., Alankus, O., Tateishi, H., Otsuka, M., Fujita, M., and Sever, B.
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 222 Pages: 1487-1499
- DOI
  10.1016/j.ijbiomac.2022.09.257
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity2022
- Author(s)
  Nakagawa Riko、Tateishi Hiroshi、Radwan Mohamed O.、Chinen Takuma、Ciftci Halilibrahim、Iwamaru Kana、Baba Nanami、Tominaga Yuna、Koga Ryoko、Toma Tsugumasa、Inoue Jun-ichiro、Umezawa Kazuo、Fujita Mikako、Otsuka Masami
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 70 Issue: 7 Pages: 477-482
- DOI
  10.1248/cpb.c21-01087
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24323, KAKENHI-PROJECT-20H03365
[Journal Article] A new series of indeno[1,2-c]pyrazoles as EGFR TK inhibitors for NSCLC therapy2022
- Author(s)
  Ozdemir, A., Ciftci, H., Sever, B., Tateishi, H., Otsuka, M., Fujita, M., and Altintop, M.D.
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 2 Pages: 485-485
- DOI
  10.3390/molecules27020485
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] In vitro and in silico study of analogs of plant product plastoquinone to be effective in colorectal cancer treatment2022
- Author(s)
  Ciftci, H., Sever, B., Ocak, F., Bayrak, N., Yildiz, M., Yildirim, H., DeMirci, H., Tateishi, H., Otsuka, M., Fujita, M., and Tuyun, A.F.
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 3 Pages: 693-693
- DOI
  10.3390/molecules27030693
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] In vitro cytotoxicity evaluation of plastoquinone analogues against colorectal and breast cancers along with in silico insights2022
- Author(s)
  Ciftci, H., Sever, B., Bayrak, N., Yildiz, M., Yildirim, H., Tateishi, H., Otsuka, M., Fujita, M., and Tuyun, A.F.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 10 Pages: 1266-1266
- DOI
  10.3390/ph15101266
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] A vitamin D C/D ring-derived compound with cytotoxicity2022
- Author(s)
  Hassan, A.N., Toma, T., Ciftci, H., Biswas, T., Tahara, Y., Radwan, M.O., Tateishi, H., Fujita, M., and Otsuka, M.
- Journal Title
  
  Medicinal Chemistry Research
  
  Volume: - Issue: 7 Pages: 1120-1125
- DOI
  10.1007/s00044-021-02842-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] In vitro and in silico study to assess toxic mechanisms of hybrid molecules of quinone-benzocaine as plastoquinone analogs in breast cancer cells2022
- Author(s)
  Goler, A.M.Y., Jannuzzi, A.T., Bayrak, N., Yildiz, M., Yildirim, H., Otsuka, M., Fujita, M., Radwan, M., and Tuyun, A.F.
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 34 Pages: 30250-30264
- DOI
  10.1021/acsomega.2c03428
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Identification of new L-heptanoylphosphatidyl inositol pentakisphosphate derivatives targeting the interaction with HIV-1 Gag by molecular modelling studies2022
- Author(s)
  Ciftci, H., Sever, B., Ayan, E., Can, M., DeMirci, H., Otsuka, M., Tuyun, A.F., Tateishi, H., and Fujita, M.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 10 Pages: 1255-1255
- DOI
  10.3390/ph15101255
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] A New Inhibitor of ADAM17 Composed of a Zinc-Binding Dithiol Moiety and a Specificity Pocket-Binding Appendage2021
- Author(s)
  Tateishi, H., Tateishi, M., Radwan, M.O., Masunaga, T., Kawatashiro, K., Oba, Y., Oyama, M., Inoue-Kitahashi, N., Fujita, M., Okamoto, Y., and Otsuka, M.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 11 Pages: 1123-1130
- DOI
  10.1248/cpb.c21-00701
- NAID
  130008109869
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy2021
- Author(s)
  Ciftci Halil I.、Radwan Mohamed O.、Sever Belgin、Hamdy Ahmed K.、Emirda? Safiye、Ulusoy N. Gokce、Sozer Ece、Can Mustafa、Yayli Nurettin、Araki Norie、Tateishi Hiroshi、Otsuka Masami、Fujita Mikako、Altintop Mehlika Dilek
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 20 Pages: 10945-10945
- DOI
  10.3390/ijms222010945
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03772, KAKENHI-PROJECT-20H03365
[Journal Article] Design and Synthesis of an Anthranyl Bridged Optically Active Dinuclear Iron(II)-Ligand and Evaluation of DNA-Cleaving Activity.2021
- Author(s)
  Ichimaru, Y., Kato, K., Okuno, Y., Yamaguchi, Y., Jin, W., Fujita, M., Otsuka, M., Imai, M., and Kurosaki, H.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 35 Pages: 127782-127782
- DOI
  10.1016/j.bmcl.2021.127782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Selective SIRT2 inhibitors as promising anticancer therapeutics: An update from 2016 to 20202021
- Author(s)
  Roshdy, I., Mustafa, M., Shaltout, A.E., Radwan, M.O., Fujita, M., Otsuka, M., and Ali, T.F.S.
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 224 Pages: 113709-113709
- DOI
  10.1016/j.ejmech.2021.113709
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Structure‐based design, synthesis, and evaluation of anti-CML activity of the quinolinequinones as LY83583 analogs2021
- Author(s)
  Bayrak, N., Ciftci, H.I., Yildiz, M., Yildirim, H., Sever, B., Tateishi, H., Otsuka, M., Fujita, M., and Tuyun, A.F.
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 345 Pages: 109555-109555
- DOI
  10.1016/j.cbi.2021.109555
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAFV600E kinases2021
- Author(s)
  Mohassab Aliaa M.、Hassan Heba A.、Abdelhamid Dalia、Gouda Ahmed M.、Youssif Bahaa G.M.、Tateishi Hiroshi、Fujita Mikako、Otsuka Masami、Abdel-Aziz Mohamed
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 106 Pages: 104510-104510
- DOI
  10.1016/j.bioorg.2020.104510
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
[Journal Article] Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M2021
- Author(s)
  Kamo Masahiro、Ito Miu、Toma Tsugumasa、Gotoh Haruna、Shimozono Rie、Nakagawa Riko、Koga Ryoko、Monde Kazuaki、Tateishi Hiroshi、Misumi Shogo、Otsuka Masami、Fujita Mikako
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 107 Pages: 104627-104627
- DOI
  10.1016/j.bioorg.2021.104627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
[Journal Article] Crystal Structures of Metallo-β-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester2021
- Author(s)
  Yamaguchi Yoshihiro、Kato Koichi、Ichimaru Yoshimi、Jin Wanchun、Sakai Misa、Abe Miki、Wachino Jun-ichi、Arakawa Yoshichika、Miyagi Yukina、Imai Masanori、Fukuishi Nobuyuki、Yamagata Yuriko、Otsuka Masami、Fujita Mikako、Kurosaki Hiromasa
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 14 Pages: 10019-10026
- DOI
  10.1021/acs.jmedchem.1c00308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02967, KAKENHI-PROJECT-17K08376, KAKENHI-PROJECT-20H03365
[Journal Article] Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein2021
- Author(s)
  Ciftci Halilibrahim、Tateishi Hiroshi et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15819-15819
- DOI
  10.1038/s41598-021-95236-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05742, KAKENHI-PROJECT-20H03365
[Journal Article] A new series of antileukemic agents: Design, synthesis, in vitro and in silico evaluation of thiazole-based ABL1 kinase inhibitors2021
- Author(s)
  Zeytun, E., Altintop, M.D., Sever, B., Ozdemir, A., Ellakwa, D.E., Ocak, Z., Ciftci, H.I., Otsuka, M., Fujita, M., and Radwan, M.O.
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry
  
  Volume: 21 Issue: 9 Pages: 1099-1109
- DOI
  10.2174/1871520620666200824100408
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] New quinoline/1,2,4-triazole hybrids as dual inhibitors of COX-2/5-LOX and inflammatory cytokines: Design, synthesis, and docking study2021
- Author(s)
  Mohassab, A.M., Hassan, H.A., Abdelhamid, D., Gouda, A.M., Gomaa, H.A.M., Youssif, B.G.M., Radwan, M.O., Fujita, M., Otsuka, M., and Abdel-Aziz, M.
- Journal Title
  
  Journal of Molecular Structure
  
  Volume: 1244 Pages: 130948-130948
- DOI
  10.1016/j.molstruc.2021.130948
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Development of chimeric receptor activator of nuclear factor‐kappa B with glutathione S‐transferase in the extracellular domain: Artificial switch in a membrane receptor2021
- Author(s)
  Kawashima Kanako、Hirota‐Tsukimachi Mayuko、Toma Tsugumasa、Koga Ryoko、Iwamaru Kana、Kanemaru Yosuke、Yanae Misato、Ahagon Ami、Nakamura Yurine、Anraku Kensaku、Tateishi Hiroshi、Gohda Jin、Inoue Jun‐ichiro、Otsuka Masami、Fujita Mikako
- Journal Title
  
  Chemical Biology & Drug Design
  
  Volume: 99 Issue: 4 Pages: 573-584
- DOI
  10.1111/cbdd.14002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05742, KAKENHI-PROJECT-20H03365
[Journal Article] Design, Synthesis, and Investigation of the Mechanism of Action Underlying Anti-Leukemic Effects of the Quinolinequinones as LY83583 Analogs2021
- Author(s)
  Ciftci, H.I., Bayrak, N., Yildiz, M., Yildirim, H., Sever, B., Tateishi, H., Otsuka, M., Fujita, M., and Tuyun, A.F.
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 114 Pages: 105160-105160
- DOI
  10.1016/j.bioorg.2021.105160
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors2020
- Author(s)
  Belgin Sever, Mehlika Dilek Altintop, Ahmet Ozdemir, Gulsen Akalin Ciftci, Doha E. Ellakwa, Hiroshi Tateishi, Mohamed O. Radwan, Mahmoud A. A. Ibrahim, Masami Otsuka, Mikako Fujita, Halil I. Ciftci and Taha F. S. Ali
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 21 Pages: 5190-5190
- DOI
  10.3390/molecules25215190
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
[Journal Article] Interruption of Vif/Elongin C interaction: In silico and experimental elucidation of the underlying molecular mechanism of benzimidazole-based APOBEC3G stabilizers2020
- Author(s)
  Radwan Mohamed O.、Takaya Daisuke、Koga Ryoko、Iwamaru Kana、Tateishi Hiroshi、Ali Taha F.S.、Takaori-Kondo Akifumi、Otsuka Masami、Honma Teruki、Fujita Mikako
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 8 Pages: 115409-115409
- DOI
  10.1016/j.bmc.2020.115409
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365, KAKENHI-PROJECT-17H03999
[Journal Article] Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition.2020
- Author(s)
  Radwan, M.O., Ciftci, H.I., Ali, T.F.S., Koga, R., Tateishi, H., Nakata, A., Ito, A., Yoshida, M., Fujita, M., Otsuka, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 30(19) Issue: 19 Pages: 127458-127458
- DOI
  10.1016/j.bmcl.2020.127458
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
[Journal Article] HSP70 induction by bleomycin metal core analogs2020
- Author(s)
  Ali Taha F.S.、Taira Naomi、Iwamaru Kana、Koga Ryoko、Kamo Masahiro、Radwan Mohamed O.、Tateishi Hiroshi、Kurosaki Hiromasa、Abdel-Aziz Mohamed、Abuo-Rahma Gamal El-Din A.A.、Beshr Eman A.M.、Otsuka Masami、Fujita Mikako
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 7 Pages: 127002-127002
- DOI
  10.1016/j.bmcl.2020.127002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365, KAKENHI-PROJECT-17H03999
[Journal Article] Antiproliferative activity of Turkish marine extracts: A purple sponge components induce apoptosis with multiple kinases inhibition2020
- Author(s)
  Ciftci, H.I., Can, M., Ellakwa, D., Suner, S., Ibrahim, M., Oral, A., Sekeroglu, N., Ozalp, B., Otsuka, M., Fujita, M., Alparslan, M., and Radwan, M.
- Journal Title
  
  Investigational New Drugs
  
  Volume: 38 Issue: 5 Pages: 1326-1333
- DOI
  10.1007/s10637-020-00911-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] Activation of Ligand Reaction on an Iron Complex: H/D Exchange Reaction of a Low-Spin Bis[2-(Pyridylmethylidene)-1-(2-pyridyl)methylamine]iron(II) Complex2020
- Author(s)
  Imai, M., Kato, K., Yamaguchi, Y., Fujita, M., Otsuka, M, and Kurosaki, H.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 8 Pages: 713-716
- DOI
  10.1248/cpb.c20-00383
- NAID
  130007883294
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03365
[Journal Article] The stability of HIV-2 Vpx and Vpr proteins is regulated by the presence or absence of zinc-binding sites and poly-proline motifs with distinct roles2020
- Author(s)
  Shimagaki Kazunori、Koga Ryoko、Fujino Haruna、Ahagon Ami、Tateishi Hiroshi、Otsuka Masami、Yamaguchi Yoshihiro、Fujita Mikako
- Journal Title
  
  Journal of General Virology
  
  Volume: 101 Issue: 9 Pages: 997-1007
- DOI
  10.1099/jgv.0.001456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
[Journal Article] Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature2019
- Author(s)
  I Ciftci Halil、G Sierra Raymond、Yoon Chun、Su Zhen、Tateishi Hiroshi、Koga Ryoko、Kotaro Koiwai、Yumoto Fumiaki、Senda Toshiya、Liang Mengling、Wakatsuki Soichi、Otsuka Masami、Fujita Mikako、DeMirci Hasan
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 7 Pages: 1675-1675
- DOI
  10.3390/ijms20071675
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-17H03999
[Journal Article] Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia2019
- Author(s)
  Noguchi Kei、Ali Taha F.S.、Miyoshi Junko、Orito Kimihiko、Negoto Tetsuya、Biswas Tanima、Taira Naomi、Koga Ryoko、Okamoto Yoshinari、Fujita Mikako、Otsuka Masami、Morioka Motohiro
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 163 Pages: 207-214
- DOI
  10.1016/j.ejmech.2018.11.060
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-18K08985, KAKENHI-PROJECT-16K10746
[Journal Article] New SIRT2 inhibitors: Histidine-based bleomycin spin-off2019
- Author(s)
  Ali Taha F.S.、Ciftci Halil I.、Radwan Mohamed O.、Koga Ryoko、Ohsugi Takeo、Okiyama Yoshio、Honma Teruki、Nakata Akiko、Ito Akihiro、Yoshida Minoru、Fujita Mikako、Otsuka Masami
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 9 Pages: 1767-1775
- DOI
  10.1016/j.bmc.2019.03.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-17H03999
[Journal Article] Anti-cancer activity of the cell membrane-permeable phytic acid prodrug2019
- Author(s)
  Masunaga Takuya、Murao Naoki、Tateishi Hiroshi、Koga Ryoko、Ohsugi Takeo、Otsuka Masami、Fujita Mikako
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 92 Pages: 103240-103240
- DOI
  10.1016/j.bioorg.2019.103240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17H03999
[Journal Article] Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis2018
- Author(s)
  Luong Vu Huy、Chino Takenao、Oyama Noritaka、Matsushita Takashi、Sasaki Yoko、Ogura Dai、Niwa Shin-ichiro、Biswas Tanima、Hamasaki Akiyuki、Fujita Mikako、Okamoto Yoshinari、Otsuka Masami、Ihn Hironobu、Hasegawa Minoru
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 20 Issue: 1 Pages: 46-46
- DOI
  10.1186/s13075-018-1534-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10165, KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-16K15143
[Journal Article] Introduction of H2C2-type zinc-binding residues into HIV-2 Vpr increases its expression level.2018
- Author(s)
  Koga, R., Yamamoto, M., Ciftci, H.I., Otsuka, M., and Fujita, M.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 1 Issue: 1 Pages: 146-153
- DOI
  10.1002/2211-5463.12358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-16K15143
[Journal Article] The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities2018
- Author(s)
  Ciftci, H.I., Ozturk, S.E., Ali, T.F.S., Radwan, M.O., Tateishi, H., Koga, R., Ocak, Z., Can, M., Otsuka, M., and Fujita, M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 4 Pages: 570-574
- DOI
  10.1248/bpb.b17-00902
- NAID
  130006602535
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143
[Journal Article] Design, synthesis and biological evaluation of novel 1,3,4-Thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia. Striking effect of nitrothiazole moiety.2018
- Author(s)
  Altintop, M.D., Ciftci, H.I., Radwan, M.O., Sever, B., Kaplancikli, Z.A., Ali, T.F.S., Koga, R., Fujita, M., Otsuka, M., and Ozdemir, A.
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 1 Pages: 59-59
- DOI
  10.3390/molecules23010059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-16K15143
[Journal Article] Role of zinc binding site of HIV-2 Vpx prevents instability and dysfunction of the protein2017
- Author(s)
  Minami Yamamoto, Ryoko Koga, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
- Journal Title
  
  J. General Virol.
  
  Volume: 98 Issue: 2 Pages: 275-283
- DOI
  10.1099/jgv.0.000701
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
[Journal Article] A clue to unprecedented strategy to HIV eradication: “Lock-in and apoptosis”.2017
- Author(s)
  Tateishi, H., Monde, K., Anraku, K., Koga, R., Hayashi, Y., Ciftci, H.I., DeMirci, H., Higashi, T., Motoyama, K, Arima, H., Otsuka, M., and Fujita, M.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 8957-8957
- DOI
  10.1038/s41598-017-09129-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
[Journal Article] A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.2017
- Author(s)
  Tanaka, A., Radwan, M.O., Hamasaki, A., Ejima, A., Obata, E., Koga, R., Tateishi, H., Okamoto, Y., Fujita, M., Nakao, M., Umezawa, K., Tamanoi, F., and Otsuka, M.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 16 Pages: 3862-3866
- DOI
  10.1016/j.bmcl.2017.06.047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
[Journal Article] A dithiol compound binds to the zinc finger protein TRAF6 and suppresses its ubiquitination.2017
- Author(s)
  Koga, R., Radwan, M.O., Ejima, T., Kanemaru, Y., Tateishi, H., Ali, T.F.S., Ciftci, H.I., Shibata, Y., Taguchi, Y., Inoue, J., Otsuka, M., and Fujita, M.
- Journal Title
  
  ChemMedChem
  
  Volume: 12 Issue: 23 Pages: 1935-1941
- DOI
  10.1002/cmdc.201700399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17K10999, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
[Journal Article] Synthesis, Computational Study, and Evaluation of in vitro Antimicrobial, Antibiofilm, and Anticancer Activities of New Sulfanyl Aminonaphthoquinone Derivatives2017
- Author(s)
  Nilufer Bayrak, Hatice Yildirim, Amac Fatih Tuyun, Emel Mataraci Kara, Berna Ozbek Celik, Girish Kumar Gupta, Halil I. Ciftci, Mikako Fujita, Masami Otsuka, Hamid R. Nasiri
- Journal Title
  
  Letters in Drug Design & Discovery,
  
  Volume: 14 Issue: 6 Pages: 647-661
- DOI
  10.2174/157018081406170606155530
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
[Journal Article] Commentary: MARCH8 Inhibits HIV-1 Infection by Reducing Virion Incorporation of Envelopes Glycoproteins.2016
- Author(s)
  Fujita M
- Journal Title
  
  Front. Microbiol.
  
  Volume: 7 Pages: 254-254
- DOI
  10.3389/fmicb.2016.00254
- NAID
  120006697194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460570
[Journal Article] Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G2016
- Author(s)
  Radwan, Mohamed O.; Sonoda, Sachiko; Ejima, Tomohiko; Tanaka, Ayumi; Koga, Ryoko; Okamoto, Yoshinari; Fujita, Mikako; Otsuka, Masami
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Issue: 18 Pages: 4398-4405
- DOI
  10.1016/j.bmc.2016.07.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-16K15143
[Journal Article] Synthesis of the biotinylated anti-HIV compound BMMP and the target identification study.2016
- Author(s)
  Kamo M, Tateishi H, Koga R, Okamoto Y, Otsuka M, Fujita M.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 26 Issue: 1 Pages: 43-45
- DOI
  10.1016/j.bmcl.2015.11.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-16K15143
[Journal Article] Mutational analysis of HIV-2 Vpx shows that residue 109 in the poly-proline motif regulates degradation of SAMHD12015
- Author(s)
  Halil Ibrahim Ciftci, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Sogo Kawamura, Hiroshi Tateishi, Yasumasa Iwatani, Masami Otsuka, Mikako Fujita
- Journal Title
  
  FEBS Letters
  
  Volume: 未定 Issue: 13 Pages: 1505-1514
- DOI
  10.1016/j.febslet.2015.04.038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-15H04740
[Journal Article] l-Histidyl-glycyl-glycyl-l-histidine. Amono-acid structuring of the bleomycin-type pentadentate metal-binding environment capable of efficient double-strand cleavage of plasmid DNA.2015
- Author(s)
  Ida S, Iwamaru K, Fujita M, Okamoto Y, Kudo Y, Kurosaki H, Otsuka M
- Journal Title
  
  Bioorg. Chem.
  
  Volume: 62 Pages: 8-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460570
[Journal Article] Mutational analysis of HIV-2Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD12015
- Author(s)
  Halil Ibrahim Ciftci, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Sogo Kawamura, Hiroshi Tateishi, Yasumasa Iwatani, Masami Otsuka, Mikako Fujita
- Journal Title
  
  FEBS Letters
  
  Volume: 589 (13) Pages: 1505-1514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670058
[Journal Article] Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system2015
- Author(s)
  Ali, Taha F. S.; Iwamaru, Kana; Ciftci, Halil Ibrahim; Koga, Ryoko; Matsumoto, Masahiro; Oba, Yasunori; Kurosaki, Hiromasa; Fujita, Mikako; Okamoto, Yoshinari; Otsuka, Masami et. al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 23 Issue: 17 Pages: 5476-5482
- DOI
  10.1016/j.bmc.2015.07.044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-26462186, KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-25462268, KAKENHI-PROJECT-26670058
[Journal Article] L-Histidyl-glycyl-glycyl-L-histidine. Amino-acid structuring of the bleomycin-type pentadentate metal-binding environment capable of efficient double-strand cleavage of plasmid DNA2015
- Author(s)
  Ida, Satomi; Iwamaru, Kana; Fujita, Mikako; Okamoto, Yoshinari; Kudo, Yuri; Kurosaki, Hiromasa; Otsuka, Masami
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 62 Pages: 8-14
- DOI
  10.1016/j.bioorg.2015.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-26670058
[Journal Article] Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents.2015
- Author(s)
  Karabacak M, Altintop MD, Ciftci H, Koga R, Otsuka M, Fujita M, Ozdemir A.
- Journal Title
  
  Molecules
  
  Volume: 20 Issue: 10 Pages: 19066-19084
- DOI
  10.3390/molecules201019066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-26670058
[Journal Article] Design and synthesis of lipid-coupled inositol 1, 2, 3, 4, 5, 6-hexakisphosphate derivatives exhibiting high-affinity binding for HIV-1 MA domain2014
- Author(s)
  Hiroshi Tateishi, Kensaku Anraku, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: (First published online) Issue: 27 Pages: 5006-5022
- DOI
  10.1039/c4ob00350k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-26670058
[Journal Article] Poly-proline motif in HIV-2 Vpx is critical for its efficient translation2014
- Author(s)
  Ariko Miyake, Mikako Fujita, Haruna Fujino, Ryoko Koga, Sogo Kawamura, Masami Otsuka, Hirotaka Ode, Yasumasa Iwatani, Yosuke Sakai, Naoya Doi, Masako Nomaguchi, Akio Adachi, Yasuyuki Miyazaki
- Journal Title
  
  Journal of General Virology
  
  Volume: 95 Issue: 1 Pages: 179-189
- DOI
  10.1099/vir.0.057364-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24590568, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-24659208, KAKENHI-PROJECT-24790443, KAKENHI-PROJECT-26670058
[Journal Article] Structural biology for virus research2012
- Author(s)
  Yasuyuki Miyazaki, Mikako Fujita, Masako Nomaguchi, Akio Adcahi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 3 Pages: 91-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] SAMHD1-dependent and-independent functions of HIV-2/SIV Vpx protein2012
- Author(s)
  Mikako Fujita, Masako Nomaguchi, Akio Adachi, Masami Otsuka
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: Vol3, Article297 Pages: 1-7
- DOI
  10.3389/fmicb.2012.00297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-24659208
[Journal Article] Commentary on aptamers for virus research2012
- Author(s)
  Yasuyuki Miyazaki, Mikako Fujita
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 3 Pages: 52-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] An Artificial Copper Complex Incorporating a Cell-penetrating Peptide Inhibits NF-B Activation2011
- Author(s)
  Yosuke Kanemaru, Yumi Momiki, Saori Matsuura, Tatsufumi Horikawa, Jin Gohda, Jun-ichiro Inoue, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 59 Pages: 1555-1558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659024
[Journal Article] An anti-HIV-1 compound that increase steady-state expression of apoplipoprotein B mRNA-editing Enzyme-catalytic polypeptide-like 3G2011
- Author(s)
  Tomohiko Ejima, Mayuko Hirota, Tamio Mizukami, Masami Otsuka, Mikako Fujita
- Journal Title
  
  Int. J. Mol. Med
  
  Volume: 28(4) Pages: 613-616
- DOI
  10.3892/ijmm.2011.737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390028
[Journal Article] The fourth major restriction factor against HIV/ SIV2011
- Author(s)
  Nomaguchi, M., Fujita, M., and Adachi, A
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 2 Pages: 132-132
- DOI
  10.3389/fmicb.2011.00132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390141, KAKENHI-PROJECT-21590511
[Journal Article] An artificial copper complex incorporating a cell-penetrating peptide inhibits NF-・B activation2011
- Author(s)
  Yosuke Kanemaru, Yumi Momiki, Saori Matsuura, Tatsufumi Horikawa, Jin Gohda, Jun-ichiro Inoue, Yoshinari Okamoto, Mikako Fujita, Masami Otuska
- Journal Title
  
  Chemical & Pharmaceutical Bulletin
  
  Volume: 59 Pages: 1555-1558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] An anti-HIV-1 compound that increase steady-state expression of apoplipoprotein B mRNA-editing Enzyme-catalytic polypep-tide-like 3G2011
- Author(s)
  Tomohiko Ejima, Mayuko Hirota, Tamio Mizukami, Masami Otsuka, Mikako Fujita
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 28 Pages: 613-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659024
[Journal Article] The fourth major restriction factor against HIV/SIV2011
- Author(s)
  Masako Nomaguchi, Mikako Fujita, Akio Adachi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 2 Pages: 132-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] An anti-HIV-1compound that increases steady-state expression of apoplipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G2011
- Author(s)
  Tomohiko Ejima, Mayuko Hirota, Tamio Mizukami, Masami Otsuka, Mikako Fujita
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 28 Pages: 613-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] An Artificial Copper Complex Incorporating a Cell-Penetrating Peptide Inhibits Nuclear Factor-.KAPPA.B (NF-.KAPPA.B) Activation2011
- Author(s)
  Yosuke Kanemaru, Yumi Momiki, Saori Matsuura, Tatsufumi Horikawa, Jin Gohda, Jun-ichiro Inoue, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 59 Issue: 12 Pages: 1555-1558
- DOI
  10.1248/cpb.59.1555
- NAID
  130001852132
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390028
[Journal Article] HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice2011
- Author(s)
  Hideki Fujii, Manabu Ato, Yoshimasa Takahashi, Kaori Otake, Shu-ichi Hashimoto, Tomohiro Kaji, Yasuko Tsunetsugu-Yokota, Mikako Fujita, Akio Adachi, Toshinori Nakamura, Masaru Taniguchi, Shigeo Koyasu, Toshiitada Takemori
- Journal Title
  
  International Immunology
  
  Volume: 23 Pages: 433-441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] Multifaced activity of HIV Vpr/Vpx proteins : the current view of their virological functions2010
- Author(s)
  Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi
- Journal Title
  
  Reviews in Medical Virology
  
  Volume: 20 Pages: 68-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] Role of HIV-1Nef protein for virus replication in vitro2010
- Author(s)
  Abhay Jere, Mikako Fujita, Akio Adachi, Masako Nomaguchi
- Journal Title
  
  Microbes and Infection
  
  Volume: 12 Pages: 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] Site-directed mutagenesis of HIV-1 vpu gene demonstrates two clusters of replication-defective mutants with distinct ability to down-regulate cell surface CD4 and tetherin2010
- Author(s)
  Masako Nomaguchi, Naoya Doi, Sachi Fujiwara, Mikako Fujita, Akio Adachi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 1 Pages: 116-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] Multifaceted activity of HIV Vpr/Vpx proteins : the current view of their virological functions2010
- Author(s)
  Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi
- Journal Title
  
  Reviews in Medical Virology
  
  Volume: 20 Pages: 68-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659024
[Journal Article] Highly Sensitive Analysis of the Interaction between HIV-1 Gag and Phosphoinositide Derivatives Based on Surface Plasmon Resonance2010
- Author(s)
  Kensaku Anraku, Ryota Fukuda, Nobutoki Takamune, Shogo Misumi, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 5109-5116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659024
[Journal Article] Highly sensitive analysis of the interaction between HIV-1Gag and phosphoinositide derivatives based on surface plasmon resonance2010
- Author(s)
  Kensaku Anraku, Ryota Fukuda, Nobutoki Takamune, Shogo Misumi, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 5109-5116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590511
[Journal Article] Multifaceted activity of HIV Vpr/Vpx proteins : the current view of their virological functions.2010
- Author(s)
  藤田美歌子
- Journal Title
  
  Rev.Med.Virol.
  
  Volume: 20 Pages: 68-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659024
[Journal Article] Unique characteristics of HIV-1 Vif expression.2005
- Author(s)
  Wang, H., Sakurai, A., Khamsri, B., Uchiyama, T., Gu, H., Adachi, A., Fujita, M.
- Journal Title
  
  Microbes and Infection 7
  
  Pages: 385-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590420
[Journal Article] High level expression of Human Immunodeficiency Virus type-1 Vif inhibits viral infectivity by modulating proteolytic processing of the Gag precursor at the p2/NC processing site.2004
- Author(s)
  Akari, H., Fujita, M., Kao, S., Khan, M.A., Shehu-Xhilaga, M., Adachi, A., Strebel, K.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 12355-12362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome-degradation.2004
- Author(s)
  Fujita, M.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 791-798
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Determination of HIV-1 infecivity by lymphocytic cell lines with integrated luciferase gene.2004
- Author(s)
  Nagao, T., Yoshida, A., Sakurai, A., Piroozmand, A., Jere, A., Fujita, M., Uchiyama, T., Adachi, A.
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 1073-1076
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome-degradation2004
- Author(s)
  Fujita, M.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 791-798
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590420
[Journal Article] Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome-degradation.2004
- Author(s)
  Fujita, M., Akari, H., Sakurai, A., Yoshida, A., Chiba, T., Tanaka, K., Strebel, K., Adachi, A.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 791-798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome-degradation.2004
- Author(s)
  Fujita, M., Akari, H., Sakurai, A., Yoshida, A., Chiba, T., Tanaka, K, Strebel, K., Adachi, A.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 791-798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590420
[Journal Article] Functional analysis of HIV-1 vif genes derived from Japanese long-term nonprogressors and progressors for AIDS.2004
- Author(s)
  Sakurai, A., Jere, A., Yoshida, A., Yamada, T., Iwamoto, A., Adachi, A., Fujita, M.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 799-805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] High-level expression of Human Immunodeficiency Virus type-1 Vif inhibits viral infectivity by modulating proteolytic processing of the Gag precursor at the p2/NC processing site.2004
- Author(s)
  Akari, H., Fujita, M., Kao, S., Khan, M., A., Shehu-Xhilaga, M., Adachi, A., Strebel, K.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 12355-12362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590420
[Journal Article] Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome-degradation.2004
- Author(s)
  Fujita, M.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 791-798
- Data Source
  KAKENHI-PROJECT-16017270
[Journal Article] Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome-degradation.2004
- Author(s)
  Fujita, M.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 791-798
- Data Source
  KAKENHI-PROJECT-15590420
[Journal Article] Generation and characterization of HIV-1 clones chimeric for subtypes B and C nef.2004
- Author(s)
  Jere, A., Piroozmand, A., Tripathy, S., Paranjape, R., Sakurai, A., Fujita, M., Adachi, A.
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 1087-1090
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Functional analysis of HIV-1 vif genes derived from Japanese long-term nonprogressors and progressors for AIDS.2004
- Author(s)
  Sakurai, A., Jere, A., Yoshida, A., Yamada, T., Iwamoto, A., Adachi, A., Fujita, M.
- Journal Title
  
  Microbes and Infection 6
  
  Pages: 799-805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590420
[Journal Article] Susceptibility of HVS-immortalized lymphocytic HSC-F cells to various strains and mutants of HIV-SIV.2003
- Author(s)
  Fujita, M., Yoshida, A., Sakurai, A., Tatsuki, J., Ueno, F., Akari, H., Adachi, A.
- Journal Title
  
  International Journal of Molecular Medicine 11
  
  Pages: 641-644
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Amino acid residues 88 and 89 in the central hydrophilic region of human immunodeficiency virus type 1 Vif are critical for viral infectivity by enhancing the steady-state expression of Vif.2003
- Author(s)
  Fujita, M., Sakurai, A., Yoshida, A., Miyaura, M., Koyama, A.H., Sakai, K., Adachi, A.
- Journal Title
  
  Journal of Virology 77
  
  Pages: 1626-1632
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Amino acid residues 88 and 89 in the central hydrophilic region of human immunodeficiency virus type 1 Vif are critical for viral infectivity by enhancing the steady-state expression of Vif.2003
- Author(s)
  Fujita, M.
- Journal Title
  
  Journal of Virology 77
  
  Pages: 1626-1632
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Vpx and Vpr proteins of HIV-2 up-regulate the viral infectivity by a distinct mechanism in lymphocytic cells.2003
- Author(s)
  Ueno, F., Shiota, H., Miyaura, M., Yoshida, A., Sakurai, A., Tatsuki J., Koyama, A.H., Akari, H., Adachi, A., Fujita, M.
- Journal Title
  
  Microbes and Infection 5
  
  Pages: 387-395
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Susceptibility of HVS-immortalized lymphocytic HSC-F cells to various strains and mutants of HIV/SIV.2003
- Author(s)
  Fujita, M.
- Journal Title
  
  International Journal of Molecular Medicine 11
  
  Pages: 641-644
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Subtle mutations in the cysteine region of HIV-1 Vif drastically alter the viral replication phenotype.2002
- Author(s)
  Fujita, M., Sakurai, A., Yoshida, A., Matsumoto, S., Miyaura, M., Adachi, A.
- Journal Title
  
  Microbes and Infection 4
  
  Pages: 621-624
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Apparent lack of trans-dominant negative effects of various vif mutants on the replication of HIV-1.2002
- Author(s)
  Fujita, M.
- Journal Title
  
  Microbes and Infection 4
  
  Pages: 1203-1207
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Apparent lack of trans-dominant negative effects of various vif mutants on the replication of HIV-1.2002
- Author(s)
  Fujita, M., Matsumoto, S., Sakurai, A., Doi, N., Miyaura, M., Yoshida, A., Adachi, A.
- Journal Title
  
  Microbes and Infection 4
  
  Pages: 1203-1207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Subtle mutations in the cysteine region of HIV-1 Vif drastically alter the viral replication phenotype.2002
- Author(s)
  Fujita, M.
- Journal Title
  
  Microbes and Infection 4
  
  Pages: 621-624
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Journal Article] Unique characteristics of HIV-1 Vif expression.
- Author(s)
  Wang, H., Sakurai, A., Khamsri, B., Uchiyama, T., Gu, H., Adachi A, Fujita, M.
- Journal Title
  
  Microbes and Infection (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370103
[Patent] 高リン血症治療用医薬用組成物2022
- Inventor(s)
  立石大、當眞嗣雅、増永拓弥、新垣唯一、藤田美歌子、外
- Industrial Property Rights Holder
  サイエンスファーム株式会社、熊本大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-047443
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03365
[Patent] 生活習慣病の予防又は治療に使用するための医薬組成物2022
- Inventor(s)
  荒木栄一、立石大、當眞嗣雅、藤田美歌子、新垣唯一、外
- Industrial Property Rights Holder
  サイエンスファーム株式会社、熊本大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-041748
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03365
[Patent] 繊維化が生じる疾患の治療用医薬用組成物2022
- Inventor(s)
  藤田美歌子、立石大、小林（甲斐）芹葉、井上陸、外
- Industrial Property Rights Holder
  サイエンスファーム株式会社、熊本大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-049108
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03365
[Patent] 体臭抑制用組成物および化粧料2021
- Inventor(s)
  立石大、藤田美歌子、Taha FS Ali、山崎斗樹、外
- Industrial Property Rights Holder
  サイエンスファーム株式会社、熊本大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-087962
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20H03365
[Patent] フィチン酸エステル誘導体2018
- Inventor(s)
  藤田美歌子、大塚雅巳、立石大、村尾直樹、増永拓弥、大杉剛生
- Industrial Property Rights Holder
  サイエンスファーム株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K08861
[Patent] APOBEC3発現向上剤及び抗HIV剤2010
- Inventor(s)
  藤田美歌子、大塚雅巳、江島智彦
- Industrial Property Rights Holder
  熊本大学
- Filing Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-22659024
[Patent] APOBEC発現向上剤及び抗HIV剤2010
- Inventor(s)
  藤田美歌子、大塚雅巳、江島智彦
- Industrial Property Rights Holder
  熊本大学
- Industrial Property Number
  2010-103182
- Filing Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] 抗ウイルス宿主因子 APOBEC3G 分解抑制化合物の探索2023
- Author(s)
  新垣唯一、加茂真宏、伊藤見宇、ラドワンモハメドオスマン、大塚雅巳、立石大、髙折晃史、藤田美歌子
- Organizer
  第37回日本エイズ学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] フィチン酸（IP6）を基盤とした中分子製剤の開発2023
- Author(s)
  増永拓弥、當眞嗣雅、新垣唯一、宮川展和、戸高幹夫、近藤龍也、荒木栄一、藤田美歌子、大塚雅巳、立石大
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] HIV感染細胞にアポトーシスを誘導する植物抽出物2023
- Author(s)
  藤田美歌子、田原由莉歌、王東星、立石大、戸上暉大、大塚雅巳、前田洋助、渡邊高志、門出和精
- Organizer
  第37回日本エイズ学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] TGF-βシグナルの下流を標的とした新規上皮間葉転換阻害薬の機能解析2023
- Author(s)
  當眞嗣雅、藤田美歌子、大塚雅巳
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 脳腫瘍を標的とした上皮間葉転換阻害薬の開発2023
- Author(s)
  坂本匡陽、當眞嗣雅、大塚雅巳、立石大、藤田美歌子
- Organizer
  第40回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 抗HIV活性と細胞遊走抑制活性をもつヘテロ環化合物の創出2023
- Author(s)
  新垣唯一、モハメドラドワン、當眞嗣雅、加茂真宏、伊藤見宇、古賀涼子、大塚雅巳、立石大、藤田美歌子
- Organizer
  日本ケミカルバイオロジー学会第17年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 脂質蓄積抑制効果を併せ持つ糖尿病治療薬候補化合物の開発2023
- Author(s)
  立石大、當眞嗣雅、新垣唯一、宮川展和、戸高幹夫、近藤龍也、荒木栄一、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] A derivative compound, HT-7, inhibits HIV-1 release by inducing BST2/tetherin on the cell surface2023
- Author(s)
  Perpetual Nyame, Akihiro Togami, Tomofumi Yoshida, Masunaga Takuya, Hiromi Terasawa, Nami Monde, Yurika Tahara, Tomohiro Sawa, Yorifumi Satou, Mikako Fujita, Yosuke, Maeda, Hiroshi Tateishi, Kazuaki Monde
- Organizer
  第37回日本エイズ学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] HIV-1の複製後期過程を標的とした薬剤のスクリーニングと機能評価2023
- Author(s)
  立石大、戸上暉大、田原由莉歌、Perpetual Nyame、寺沢広美、門出奈美、大塚雅巳、前田洋助、門出和精、藤田美歌子
- Organizer
  日本ケミカルバイオロジー学会第17年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 新規TGF-β/SMADシグナル阻害剤の合成及び機能解析2023
- Author(s)
  中原涼晴、立石大、當眞嗣雅、坂本貴、坂本匡陽、藤田美歌子、大塚雅巳
- Organizer
  第40回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 多発性骨髄腫治療薬を用いた新規p97/VCP阻害剤の開発2023
- Author(s)
  藤田美歌子、大塚雅巳
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] Novel Bioactive Compound from Gypsogenin Aglycone2022
- Author(s)
  Safiye Emirdag;, N. Gokce Ulusoy-Akkum, Ece Sozer, Nurettin Yayi;, Mehran Aksel, Halil Ciftci, Mohamed O. Radwan, Mikako Fujita, Masami Otsuka
- Organizer
  The 5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] MAドメインとカルジオリピンとの結合を基軸とした抗HIV化合物の創製2022
- Author(s)
  知念拓磨、立石大、島垣和功、福田亮太、Mohamed O Radwan、坂本亜里紗、三隅将吾、大塚雅巳、藤田美歌子、安楽健作
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] ポリプロリンモチーフによるHIV-2 Vpr/Vpx蛋白質発現量制御のメカニズム2022
- Author(s)
  藤田美歌子、阿波根あみ、中村由莉音、島垣和功、古賀涼子、藤野悠那、大塚雅巳、立石大
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] Studies aiming at new strategies to combat HIV2022
- Author(s)
  Mikako Fujita
- Organizer
  10th Drug Chemistry Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] TGF-βシグナルの下流を標的とした新規上皮間葉転換阻害剤の機能解析2022
- Author(s)
  當眞嗣雅、立石大、藤田美歌子、大塚雅巳
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 脂肪蓄積抑制効果を併せ持つ糖尿病治療薬候補化合物の開発研究2022
- Author(s)
  立石大、當眞嗣雅、新垣唯一、宮川展和、戸高幹夫、近藤龍也、荒木栄一、大塚雅巳、藤田美歌子
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] メトホルミンに代わる新規糖尿病治療薬候補化合物の開発研究2022
- Author(s)
  増永拓弥、當眞嗣雅、新垣唯一、宮川展和、戸高幹夫、近藤龍也、荒木栄一、藤田美歌子、大塚雅巳、立石大
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 上皮間葉転換を標的としたがん転移阻害剤の開発2022
- Author(s)
  當眞嗣雅、立石大、川上健作、中島雄太、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] ブレオマイシンからの金属部位のスピンアウトによる活性変換2021
- Author(s)
  大塚雅巳、Radwan Mohamed、Ali Taha、Ciftci Halil、立石大、藤田美歌子
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] MAドメインとカルジオリピンとの結合を基軸とした抗エイズ薬の創製2021
- Author(s)
  立石大、知念拓磨、島垣和功、坂本亜里紗、田辺幹雄、千田俊哉、三隅将吾、大塚雅巳、藤田美歌子、安楽健作
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] ヘテロ環化合物がもつ抗細胞遊走活性の結合タンパク質同定に基づいた発見2021
- Author(s)
  立石大、加茂真宏、伊藤見宇、當眞嗣雅、後藤はるな、下園理恵、中川莉子、古賀涼子、門出和精、三隅将吾、大塚雅巳、藤田美歌子
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] HIV-1 Gag MAドメインとカルジオリピン誘導体との結合解析2021
- Author(s)
  知念拓磨、立石大、島垣和功、福田亮太、坂本亜里紗、三隅将吾、大塚雅巳、藤田美歌子、安楽健作
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] Discovery of another activity of anti-HIV heterocyclic compound2021
- Author(s)
  Hiroshi Tateishi, Masahiro Kamo, Miu Ito, Tsugumasa Toma, Haruna Gotoh, Rie shimozono, Riko Nakagawa, Ryoko Koga, Kazuaki Monde, Shogo Misumi, Masami Otsuka, Mikako Fujita
- Organizer
  The 22nd Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] HIV-1複製の後期過程を標的とした薬剤スクリーニング2021
- Author(s)
  門出和精、立石大、戸上暉大、吉田知史、寺沢広美、門出奈美、藤田美歌子、澤智裕、前田洋助
- Organizer
  第35回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] Multimerization of HIV proteins2021
- Author(s)
  Mikako Fujita
- Organizer
  5th International Joint Science Congress of Materials and Polymers (ISCMP-V)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] フィチン酸プロドラッグ体の合成と機能解析2020
- Author(s)
  増永拓弥、立石大、石橋拓朗、村尾直樹、古賀涼子、大杉剛生、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HIVリザーバーの除去または不活化を目指した新規治療法開発2020
- Author(s)
  藤田美歌子
- Organizer
  第34回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-20H03365
[Presentation] 抗HIV活性を持つヘテロ環化合物BMMPの作用機序解明と構造の改変2019
- Author(s)
  加茂真宏、立石大、岡本良成、三隅将吾、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] 細胞膜透過性を向上したIP6誘導体の合成と活性評価2019
- Author(s)
  増永拓弥、立石大、村尾直樹、古賀涼子、藤田美歌子、大塚雅巳
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HIV-2 VpxのポリプロリンモチーフはGag非存在下での蛋白質プロテアソーム分解を防ぐ2018
- Author(s)
  島垣和功、古賀涼子、藤野悠那、チッフチハリルイブラヒム、山本充奈美、大塚雅巳、藤田美歌子
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] 創薬を目指したHIV-1 Gag MAドメインとカルジオリピンとの結合解析2018
- Author(s)
  安楽健作、立石　大、古賀涼子、福田亮太、坂本亜里紗、大塚雅巳、藤田美歌子
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Development of a novel method for HIV eradication:“lock-in and apoptosis”2018
- Author(s)
  Hiroshi Tateishi, Halil Ibrahim Ciftci, Ryoko Koga, Kazuaki Monde, Kensaku Anraku, Kotaro Koiwai, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
- Organizer
  Frontiers in Retrovirology Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HNEを標的とした新規脳保護薬2018
- Author(s)
  Tanima Biswas, Taha Farouk Shehata Ali, 平尚未、古賀涼子、森美晴、岡本良成、藤田美歌子、折戸公彦、野口慶、三好淳子、森岡基浩、大塚雅巳
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Kinase Inhibitory Activity of Glycyrrhetic Acid.2018
- Author(s)
  Halil I Ciftci, Mohamed O Radwan, Masami Otsuka, Mikako Fujita
- Organizer
  The 4th International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HIV-2 VprにHHCC型亜鉛結合部位を導入すると発現量が上がる2018
- Author(s)
  古賀涼子、山本充奈美、島垣和功、立石　大、大塚雅巳、藤田美歌子
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HNEを標的とした新規脳保護薬2018
- Author(s)
  Tanima Biswas, Taha Farouk Shehata Ali, 平尚未、古賀涼子、森美晴、岡本良成、藤田美歌子、折戸公彦、野口慶、三好淳子、森岡基浩、大塚雅巳
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] IV-2 Vpxは亜鉛結合部位とポロプロリンモチーフにより発現量を上げる2018
- Author(s)
  島垣和功、古賀涼子、藤野悠那、チッフチハリルイブラヒム、山本充奈美、大塚雅巳、藤田美歌子
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HIV study aiming at elucidation of viral evolution tactics and development of a way for eradication.2018
- Author(s)
  Mikako Fujita
- Organizer
  The 4th International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Kinase Inhibitory Activity of Glycyrrhetic Acid2018
- Author(s)
  Halil I Ciftci, Mohamed O Radwan, Masami Otsuka, Mikako Fujita
- Organizer
  The 4th International Symposium on Pharmaceutical and Biomedical Sciences
- Invited
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] 抗HIV活性を持つ新規フラーレン誘導体の作用機序解明2018
- Author(s)
  加茂真宏、安野拓実、高橋恭子、大塚雅巳、大江知之、増野匡彦、藤田美歌子
- Organizer
  第32回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HIV根絶を目指した人工イノシトールリン脂質誘導体の開発2018
- Author(s)
  立石　大、安楽健作、古賀涼子、チッフチハリルイブラヒム、大塚雅巳、藤田美歌子
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Zinc-Binding State of HIV-2 VPX/VPR Regulates2017
- Author(s)
  Ryoko Koga, Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
- Organizer
  The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Host Factor vs Virus: Characters of Viral Restriction Proteins and Anti-viral Strategy.2017
- Author(s)
  Mikako Fujita
- Organizer
  Turkish-Japanese Workshop on Bioorganic Medicinal Chemistry and Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] ウイルス蛋白質蓄積によりアポトーシスを誘導する新規抗HIV薬の創製2017
- Author(s)
  立石大、門出和精、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] HIV-2 Vpxのポリプロリンモチーフの役割2017
- Author(s)
  島垣和功、古賀涼子、Halil Ibrahim Ciftci、大塚雅巳、山口佳宏、藤田美歌子
- Organizer
  第31回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Expression Level of HIV-2 Vpx/Vpr Proteins is Regulated by their Zinc Binding2017
- Author(s)
  Ryoko Koga, Minami Yamamoto, Hiroshi Tateishi, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Structural basis of inositol phosphates recognition in the HIV-1 gag matrix2017
- Author(s)
  Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6. Toward the Development of IP6 Derivative.2017
- Author(s)
  Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] TRAF6 polyubiquitination interruption by a low molecular weight zinc chelator2017
- Author(s)
  Mohamed O. Radwan, Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Hiroshi Tateishi, Taha F. S. Ali, Halil Il Ciftci, Yuri Shibata, Yuu Taguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Structural Basis of Targeting HIV-Gag Matrix, Towards Finding a Cure for HIV Infection2017
- Author(s)
  Halil Ibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
- Organizer
  The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] HIV-2 Vpxのポリプロリンモチーフの役割2017
- Author(s)
  島垣和功、古賀涼子、Halil Ibrahim Ciftci、大塚雅巳、山口佳宏、藤田美歌子
- Organizer
  第31回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] ウイルス蛋白質蓄積によりアポトーシスを誘導する新規抗HIV薬の創製2017
- Author(s)
  立石大、門出和精、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] New Sirt2 Inhibitor Based on S-Triryl-L-cysteins Scaffold.2017
- Author(s)
  Mohamed Osman Radwan, Taha F. S. Ali, Halil Ibrahim Ciftci, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Organizer
  The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] New Sirt2 Inhibitor based on S-Triryl-L-cysteins scaffold2017
- Author(s)
  Mohamed Osman Radwan, Taha F. S. Ali, Halil Ibrahim Ciftci, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Organizer
  The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6. Toward the Development of IP6 Derivative2017
- Author(s)
  Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] HIV-2 Vpx/Vpr蛋白質の発現量は亜鉛結合によって制御されている2017
- Author(s)
  Ryoko Koga, Minami Yamamoto, Hiroshi Tateishi, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Structural basis of inositol phosphates recognition in the HIV-1 gag matrix.2017
- Author(s)
  Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Zinc-Binding State of HIV-2 VPX/VPR Regulates Their Protein Stability.2017
- Author(s)
  Ryoko Koga, Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
- Organizer
  The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] Structural Basis of Targeting HIV-Gag Matrix. Towards Finding a Cure for HIV Infection.2017
- Author(s)
  Halil Ibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
- Organizer
  The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08861
[Presentation] TRAF6 polyubiquitination interruption by a low molecular weight zinc chelator2017
- Author(s)
  Mohamed O. Radwan, Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Hiroshi Tateishi, Taha F. S. Ali, Halil Il Ciftci, Yuri Shibata, Yuu Taguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] DHMEQを基盤とした新しい生物活性物質の設計と合成、および機能解析2016
- Author(s)
  本邑健太、岡本良成、古賀涼子、馬塲菜々美、藤田美歌子、梅澤一夫、大塚雅巳
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学郡元キャンパス
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Role of zinc binding site of HIV-2 Vpx2016
- Author(s)
  Minami Yamamoto, Ryoko Koga, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
- Organizer
  2 nd Kumamoto IRCMS International Symposium and 17 th Kumamoto AIDS Seminar
- Place of Presentation
  熊本県民交流館パレア
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Synthesis and applications of biotinylated zinc binding SN12016
- Author(s)
  Mohamed Radwan, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Elucidation of action mechanism of heterocyclic compound BMMP having anti-HIV activity2016
- Author(s)
  Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] 抗HIV活性を持つヘテロ環化合物BMMPの作用機序解明2016
- Author(s)
  加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、三隅将吾、大塚雅巳、藤田美歌子
- Organizer
  第30回日本エイズ学会学術集会
- Place of Presentation
  かごしま県民交流センター
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Design and synthesis of small molecule Hsp70 inducers2016
- Author(s)
  Taha Ali, Naomi Taira, Ryoko Koga, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
- Organizer
  252nd American Chemical Society Annual Meeting
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor APOBEC3G2016
- Author(s)
  Mohamed Radwan, Sachiko Sonoda, Tomohiko Ejima, Ayumi Tanaka, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Organizer
  252nd American Chemical Society Annual Meeting
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Synthesis and applications of biotinylated zinc binding SN12016
- Author(s)
  RADWAN Mohamed、KOGA Ryoko、OKAMOTO Yoshinari、FUJITA Mikako、OTSUKA Masami
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] 金属キレーターによるHSP70蛋白質の発現上昇2016
- Author(s)
  平尚未、タハ　ファロウク　シェハタ　アリ、古賀涼子、大塚雅巳、藤田美歌子
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学郡元キャンパス
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] 抗HIV剤BMMPの作用機序解明と活性改良2016
- Author(s)
  加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] 抗HIV剤BMMPの作用機序解明と活性改良2016
- Author(s)
  加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Gag蛋白質を標的とした細胞死誘導型新規抗HIV薬の開発研究2016
- Author(s)
  立石大、門出和精、村尾直樹、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Lock-in and apoptosis strategy using a PI(4,5)P2 analog aiming at eradication of HIV2016
- Author(s)
  Hiroshi Tateishi, Kazuaki Monde, Kensaku Anraku, Ryoko Koga, Yuya Hayashi, Keiichi Motoyama, Hidetoshi Arima, Masami Otsuka, Mikako Fujita
- Organizer
  2 nd Kumamoto IRCMS International Symposium and 17 th Kumamoto AIDS Seminar
- Place of Presentation
  熊本県民交流館パレア
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] A PI(4,5)P2 analog suppresses HIV-1 release and locked-in viralprotein.2016
- Author(s)
  Hiroshi Tateishi, Kazuaki Monde, Ryoko Koga, Yuya Hayashi, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kensaku Anraku, Masami Otsuka, Mikako Fujita
- Organizer
  Cold Spring Harbor Meeting, Retroviruses, 2016
- Place of Presentation
  Cold Spring Harbor Laboratory, NY, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Restructuring of the bleomycin Metal Core2016
- Author(s)
  Taha F. S. Ali, Satomi Ida, Yosuke Kanemaru, Ryoko Koga, Ayumi Tanaka, Akiyuki Hamasaki, Tomohiko Ejima, Mohamed Osman Radwan, Halil Ibrahim Ciftci, Hiromasa Kurosaki, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
- Organizer
  Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
- Place of Presentation
  熊本大学薬学部宮本記念館
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Characters of largely overexpressed HIV accessory proteins Vpx and Vif2016
- Author(s)
  Kazunori Shimagaki, Halil Ibrahim Ciftci, Ryoko Koga, Haruna Fujino, Minami Yamamoto, Yoshihiro Yamaguchi, Masami Otsuka, Mikako Fujita
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] Gag蛋白質を標的とした細胞死誘導型新規抗HIV薬の開発研究2016
- Author(s)
  立石大、門出和精、村尾直樹、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] A PI(4,5)P2 analog suppresses HIV-1 release and locked-in viral protein2016
- Author(s)
  Hiroshi Tateishi, Kazuaki Monde, Ryoko Koga, Yuya Hayashi, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kensaku Anraku, Masami Otsuka, Mikako Fujita
- Organizer
  Cold Spring Harbor Meeting, Retroviruses, 2016
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] 亜鉛結合性低分子化合物によるTRAF6および下流シグナル経路に対する影響2016
- Author(s)
  古賀涼子、Mohamed O. Radwan、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  第39回日本分子生物学年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K15143
[Presentation] New strategy to suppress HIV release by a PI(4,5)P2 mimic2015
- Author(s)
  Mikako Fujita, Hiroshi Tateishi, Kazuaki Monde, Naoki Murao, Yuya Hayashi, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kensaku Anraku, Masami Otsuka
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Development of a low molecular compound targetting TRAF6 protein2015
- Author(s)
  Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Yuri Shibata, Yuu Taguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto
- Place of Presentation
  熊本大学
- Year and Date
  2015-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Roles of the zinc finger and poly-proline motifs in HIV-2 Vpx protein2015
- Author(s)
  Halil Ibrahim Ciftci, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Masami Otsuka, Mikako Fujita,
- Organizer
  Cold Spring Harbor Meeting, Retroviruses, 2015
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2015-05-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] TRAF6ポリユビキチン化を抑制する低分子化合物によるシグナル伝達制御の検討2015
- Author(s)
  古賀涼子、江島智彦、金丸陽亮、柴田祐里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Elucidation of action mechanism of BMMP and synthesis of derivatives to improve activity2015
- Author(s)
  Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
- Organizer
  第29回日本エイズ学会学術集会
- Place of Presentation
  東京ドームホテル
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Roles of poly-proline motif of HIV-2 protein2015
- Author(s)
  Halil Ibrahim Ciftci, Demirci Hasan, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Masami Otsuka, Mikako Fujita
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Roles of poly-proline motif of HIV-2 Vpx protein2015
- Author(s)
  Ciftci Halil Ibrahim, Demirci Hasan, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Masami Otsuka, Mikako Fujita
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Pr55Gag蛋白質を標的とした新規抗HIV剤の開発研究2015
- Author(s)
  立石大、門出和精、村尾直樹、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Elucidation of action mechanism of BMMP and improvement of its activity by chemical modification2015
- Author(s)
  Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Elucidation of action mechanism of BMMP and improvement of its activity by chemical modification2015
- Author(s)
  Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Roles of zinc-binding motif of HIV-2 Vpx protein2015
- Author(s)
  Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Ryoko Koga, Ciftci Halil Ibrahim, Masami Otsuka Mikako Fujita
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Development of a low molecular compound targetingTRAF6 protein2015
- Author(s)
  Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Yuri Shibata, Yuu Taniguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto
- Place of Presentation
  熊本大学大江キャンパス
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Roles of zinc-binding motif of HIV-2 Vpx protein2015
- Author(s)
  Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Ryoko Koga, Ciftci Halil Ibrahim, Masami Otsuka, Mikako Fujita
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] SAMHD1分解におけるHIV-2 Vpx C末端ポリプロリンモチーフの役割2015
- Author(s)
  藤田美歌子、Halil Ibrahim Ciftci、藤野悠那、古賀涼子、山本充奈美、大塚雅巳
- Organizer
  第29回日本エイズ学会学術集会
- Place of Presentation
  東京ドームホテル
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] SAMHD1分解によるHIV-2 Vpx C末端ポリプロリンモチーフの役割2015
- Author(s)
  藤田美歌子、Halil Ciftci Ibrahim, 藤野悠那、古賀涼子、山本充奈美、大塚雅巳
- Organizer
  第29回日本エイズ学会学術集会
- Place of Presentation
  東京ドームホテル
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Pr55Gag蛋白質を標的とした新規抗HIV剤の開発研究2015
- Author(s)
  立石大、門出和精、村尾直樹、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] TRAF6ポリユビキチン化を抑制する低分子化合物によるシグナル伝達制御の検討2015
- Author(s)
  古賀涼子、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] New strategy to suppress HIV release by a PI(4,5)P2 mimic2015
- Author(s)
  Mikako Fujita, Hiroshi Tateishi, Kazuaki Monde, Naoki Murao, Yuya Hayashi, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kensaku Anraku, Masami Otsuka
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] Mutational analysis of HIV-2 Vpx concerning on ability to degrade SAMHD12014
- Author(s)
  Ciftci Halil Ibrahim、藤野悠那、古賀涼子、山本充奈美、川村宗吾、岩谷靖雅、大塚雅巳、藤田美歌子
- Organizer
  第28回日本エイズ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] HIV-2 Vpxにおける亜鉛フィンガー、ポリプロリンモチーフの役割と翻訳後修飾の意義2014
- Author(s)
  山本充奈美、古賀涼子、藤野悠那、Halil Ibrahim Ciftci、大塚雅巳、藤田美歌子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] SAMHD1-independent functions of HIV-2 Vpx protein2014
- Author(s)
  Mikako Fujita, Halil Ibrahim Ciftci, Minami Yamamoto, Haruna Fujino, Ryoko Koga, Sogo Kawamura, Yasumasa Iwatani, Masami Otsuka
- Organizer
  Cold Spring Harbor Laboratory Meeting, Retroviruses
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2014-05-20
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] HIV-2 Vpxにおける亜鉛フィンガーおよびC末端ポリプロリンモチーフの役割2014
- Author(s)
  藤野悠那、山本充奈美、Halil Ibrahim Ciftci、島垣和功、古賀涼子、大塚雅巳、藤田美歌子
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製2013
- Author(s)
  加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学, 長崎
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体2013
- Author(s)
  立石大, 安楽健作, 古賀涼子, 藤田美歌子, 大塚雅巳
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製2013
- Author(s)
  加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島アステールプラザ, 広島
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-1 MA 蛋白質と強く結合するイノシトールリン脂質誘導体の合成と評価2013
- Author(s)
  安楽健作, 立石大, 古賀涼子, 東大志, 本山敬一, 有馬英俊, 大塚雅巳, 藤田美歌子
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用2013
- Author(s)
  古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学, 長崎
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価2013
- Author(s)
  立石大, 安楽健作, 古賀涼子, 岡本良成, 藤田美歌子, 大塚雅巳
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島アステールプラザ, 広島
- Year and Date
  2013-11-20
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] ペプチド性新規DNA切断分子の設計と合成2013
- Author(s)
  井田智弓, 岡本良成, 藤田美歌子, 黒崎博雅, 大塚雅巳
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学, 長崎
- Year and Date
  2013-12-08
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] SAMHD1-independent function of HIV-2 Vpx protein2013
- Author(s)
  チッフチハリルイブラヒム、古賀涼子、岩谷靖雅、野間口雅子、足立昭夫、大塚雅巳、藤田美歌子
- Organizer
  第２７回日本エイズ学会学術集会
- Place of Presentation
  崇城大学ホール
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] マクロファージにおけるSAMHD1非依存的なHIV-2 Vpxの機能2013
- Author(s)
  山本充奈美、野間口雅子、古賀涼子、岩谷靖雅、高宗暢暁、三隅将吾、大塚雅巳、足立昭夫、藤田美歌子
- Organizer
  第６１回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用2013
- Author(s)
  古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島アステールプラザ, 広島
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-2 Vpx蛋白質の多量化の解析2013
- Author(s)
  藤野悠那、古賀涼子、大塚雅巳、藤田美歌子
- Organizer
  第６１回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25460570
[Presentation] イノシトールリン酸を基盤とした生物機能性分子の設計と合成2012
- Author(s)
  安楽健作, 舛田岳史, 立石大, 岡本良成, 藤田美歌子, 大塚雅巳
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  タワーホール船堀, 東京
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] 抗エイズ活性をもつイノシトールリン脂質誘導体の合成2012
- Author(s)
  安楽健作、立石大、藤田美歌子、大塚雅巳
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] 亜鉛フィンガー蛋白質阻害剤SN-1 の作用機序解明を目指した研究2012
- Author(s)
  園田祥子, 安楽健作, 古賀涼子, 田口祐, 井上純一郎, 岡本良成, 藤田美歌子, 大塚雅巳
- Organizer
  第29回日本薬学会九州支部大会
- Place of Presentation
  熊本大学薬学部, 熊本
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体2012
- Author(s)
  立石大, 安楽健作, 大塚雅巳, 藤田美歌子
- Organizer
  第26回日本エイズ学会学術集会
- Place of Presentation
  慶應義塾大学日吉キャンパス, 横浜
- Year and Date
  2012-11-24
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] PHドメイン分子によるHIV-1放出の抑制2011
- Author(s)
  藤田美歌子、安楽健作、大塚雅巳
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  ハイアットリージェンシー東京(東京)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] Design and Synthesis of Anti-HIV-1 Agent that Targets Pr55Gag Protein2011
- Author(s)
 Kensaku Anraku, Mikako Fujita, Masami Otsuka
- Organizer
 8^<th> AFMC International Medicinal Chemistry Symposium
- Place of Presentation
 京王プラザホテル(東京)
- Year and Date
 2011-11-30
- Data Source
 KAKENHI-PROJECT-22659024
[Presentation] 酸性脂質類によるHIV-1増殖の抑制2011
- Author(s)
  安楽健作、大塚雅巳、藤田美歌子
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  ハイアットリージェンシー東京(東京)
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] 酸性脂質類によるHIV-1増殖の抑制2011
- Author(s)
  安楽健作、藤田美歌子、大塚雅巳
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  ハイアットリージェンシー東京(東京)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-22659024
[Presentation] Design and Synthesis of Anti-HIV-1 Agent that Targets Pr55Gag Protein2011
- Author(s)
  Kensaku Anraku, Mikako Fujita, Masami Otsuka
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  京王プラザホテル, 東京
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] 新規チオール化合物の合成と機能解析2011
- Author(s)
  肥田知浩、金丸陽亮、岡本良成、藤田美歌子、大塚雅巳
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部(福岡)
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22659024
[Presentation] PHドメイン分子によるHIV-1放出の制御2011
- Author(s)
  藤田美歌子、安楽健作、大塚雅巳
- Organizer
  第25回日本エイズ学会学術集会
- Place of Presentation
  ハイアットリージェンシー東京(東京)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-22659024
[Presentation] HIV-1 MA蛋白質と強く結合する低分子化合物の探索2010
- Author(s)
  安楽健作、福田亮太、大塚雅巳、藤田美歌子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島あわぎんホール(徳島)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-22659024
[Presentation] HIV MAおよびNef蛋白質と脂質類との結合解析2010
- Author(s)
  福田亮太、安楽健作、大塚雅巳、藤田美歌子
- Organizer
  第24回日本エイズ学会学術集会
- Place of Presentation
  グランドプリンスホテル高輪/ザ・プリンスさくらタワー東京(東京)
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] HIV Vpr/Vpx蛋白質の役割2010
- Author(s)
  藤田美歌子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  あわぎんホール(徳島)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] HIV Vpr/Vpx蛋白質の役割2010
- Author(s)
  藤田美歌子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  あわぎんホール(徳島県)(招待講演)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-22659024
[Presentation] HIV-1増殖を制御するフラーレン化合物の開発2010
- Author(s)
  藤田美歌子、大塚雅巳、高橋恭子、中村成夫、増野匡彦
- Organizer
  第24回日本エイズ学会学術集会
- Place of Presentation
  グランドプリンスホテル高輪/ザ・プリンスさくらタワー東京(東京)
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] Pr55^<Gag>を標的とした抗HIV-1薬開発のための基礎的研究2010
- Author(s)
 安楽健作、福田亮太、藤田美歌子、大塚雅巳
- Organizer
 第29回メディシナルケミストリーシンポジウム
- Place of Presentation
 京都テルサ(京都)
- Year and Date
 2010-11-18
- Data Source
 KAKENHI-PROJECT-22659024
[Presentation] HIV-1Gag関連蛋白質およびNefとイノシトールリン酸類との結合解析2009
- Author(s)
  福田亮太、安楽健作、大塚雅巳、藤田美歌子
- Organizer
  第23回日本エイズ学会学術集会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] HIV-1複製に関与するイノシトールリン脂質類とGag関連蛋白質との結合の定量的解析2009
- Author(s)
  藤田美歌子、安楽健作、大塚雅巳
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  都市センターホテル(東京)
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-21590511
[Presentation] HIV-1蛋白質とイノシトールリン酸との結合解析2008
- Author(s)
  藤田美歌子
- Organizer
  第22回日本エイズ学会学術集会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-19590480
[Presentation] Gagに作用する抗HIV剤BMMPの作用機序解明と活性改良の試み
- Author(s)
  加茂真宏、立石大、岡本良成、森川裕子、大塚雅巳、藤田美歌子
- Organizer
  第28回日本エイズ学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] HIV-2 Vpxにおける亜鉛フィンガー、ポリプロリンモチーフの役割と翻訳後修飾の意義
- Author(s)
  山本充奈美、藤野悠那、古賀涼子、チッフチハリル、三隅将吾、大塚雅巳、藤田美歌子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] ペプチド性新規DNA切断分子の設計と合成
- Author(s)
  井田智弓、岡本良成、藤田美歌子、黒崎博雅、大塚雅巳
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学（長崎県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] SAMHD1-independent function of HIV-2 Vpx protein
- Author(s)
  チッフチ　ハリル　イブラヒム、古賀涼子、岩谷靖雅、野間口雅子、足立昭夫、大塚雅巳、藤田美歌子
- Organizer
  第27回日本エイズ学会学術集会
- Place of Presentation
  熊本国際交流会館（熊本県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用
- Author(s)
  古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島アステールプラザ（広島県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価
- Author(s)
  立石大、安楽健作、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島アステールプラザ（広島県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗ＨＩＶ薬の創製
- Author(s)
  加茂真宏、岡本良成、大塚雅巳、藤田美歌子
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学（長崎県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] マクロファージにおけるSAMHD1非依存的なHIV-2 Vpxの機能
- Author(s)
  山本充奈美、野間口雅子、古賀涼子、岩谷靖雅、高宗暢暁、三隅将吾、大塚雅巳、足立昭夫、藤田美歌子
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV-2 Vpx蛋白質の多量化の解析
- Author(s)
  藤野悠那、古賀涼子、大塚雅巳、藤田美歌子
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] Gag に作用する抗 HIV 化合物 BMMP の作用機序解明と活性改良の検討
- Author(s)
  加茂真宏、立石大、岡本良成、森川裕子、大塚雅巳、藤田美歌子
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] HIV-1放出阻害を目指したイノシトールリン脂質誘導体の創製
- Author(s)
  立石大、安楽健作、村尾直樹、古賀涼子、岡本良成、大塚雅巳、藤田美歌子
- Organizer
  第28回日本エイズ学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Crystal Structure of IMP-1 Metallo--lactamase in Complex with Citric Acid and Inhibition by Citric Acid Derivative
- Author(s)
  黒崎博雅、山口佳宏、安部美希、山縣ゆり子、荒川宜親、柴山恵吾、藤田美歌子、岡本良成、大塚雅巳
- Organizer
  88回日本細菌学会総会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用
- Author(s)
  古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学（長崎県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIVアクセサリータンパク質Nef翻訳に重要なNef2 mRNAの5’非翻訳領域
- Author(s)
  高宗暢暁、山本充奈美、原田圭輔、藤田美歌子、大塚雅巳、杉本幸彦、庄司省三、三隅将吾
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] TRAF6ポリユビキチン化を抑制する低分子化合物のシグナル伝達経路ｈｗの作用と抑制メカニズムの検討
- Author(s)
  古賀涼子、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] HIV-1 MA 蛋白質とホスファチジルイノシトール 4,5-2 リン酸との結合部位を標的とした抗 HIV 薬の設計と合成
- Author(s)
  安楽健作、立石大、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] カルバゾールとフェノチアジン誘導体の設計・合成および抗ガン活性の評価
- Author(s)
  チッフチハリルイブラヒム、Aysenur Erdogana、Emire Arkan、古賀涼子、大塚雅巳、藤田美歌子、Mahmur Kus、Mustafa Can
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] 新規HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の創製
- Author(s)
  立石大、安楽健作、村尾直樹、門出和精、原田信志、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Novel metal chelating molecules with anticancer activity
- Author(s)
  Ali Taha、岩丸佳奈、Cifti Halil、古賀涼子、黒崎博雅、藤田美歌子、岡本良成、秀拓一郎、牧野敬史、倉津純一、中尾光善、梅澤一夫、Abdel-Aziz Mohamed、Abuo-Rahma Gamal El-Din、Reshr Eman
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] Nef2 mRNAの5’非翻訳領域に含まれるNef翻訳に重要なcis領域
- Author(s)
  高宗暢暁、山本充奈美、原田圭輔、藤田美歌子、大塚雅巳、杉本幸彦、庄司省三、三隅将吾
- Organizer
  第27回日本エイズ学会学術集会
- Place of Presentation
  熊本国際交流会館（熊本県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] Mutational Analysis of HIV-2 Vpx concerning on ability to degrade SAMHD1
- Author(s)
  Ciftci Halil Ibrahim、藤野悠那、古賀涼子、山本充奈美、川村宗吾、岩谷靖雅、大塚雅巳、藤田美歌子
- Organizer
  第28回日本エイズ学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗ＨＩＶ薬の創製
- Author(s)
  加茂真宏、岡本良成、大塚雅巳、藤田美歌子
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島アステールプラザ（広島県）
- Data Source
  KAKENHI-PROJECT-23390028
[Presentation] HIV2 Vpx における亜鉛フィンガーおよび C 末端ポリプロリンモチーフの役割
- Author(s)
  藤野悠那、山本充奈美、Halil Ibrahim Ciftci、島垣和功、古賀涼子、大塚雅巳、藤田美歌子
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] TRAF6ポリユビキチン化を制御する低分子化合物のシグナル伝達阻害と制御メカニズムに関する検討
- Author(s)
  古賀涼子、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26670058
[Presentation] 抗HIV剤BMMPの作用機序解明と構造改変の試み
- Author(s)
  加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、三隅将吾、大塚雅巳、藤田美歌子
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670058

1. OTSUKA Masami (40126008)

# of Collaborated Projects: 9 results

# of Collaborated Products: 168 results
2. ADACHI Akio (90127043)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
3. OKAMOTO Yoshinari (20194409)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
4. KOYAMA Hajime (80109074)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. UCHIYAMA Tsuneo (90151901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 立石大 (50846011)

# of Collaborated Projects: 2 results

# of Collaborated Products: 44 results
7. ANRAKU Kensaku (80389543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. KUROSAKI Hiromasa (70234599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 荒木令江 (80253722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 武笠晃丈 (90463869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福島聡 (50398210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 江良択実 (00273706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小林大樹 (20448517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 北川孝雄 (20614928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 南部晶子 (40572087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 大杉剛生 (00211102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. SEVER BELGIN

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
18. WACHINO Jun-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 池本敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 伊藤昭博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 吉田稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. CIFTCI HALIL

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
23. 尹浩信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 野間口雅子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJITA MIKAKO 藤田 美歌子

FUJITA Mikako 藤田 美歌子

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Development of edaravone-c-Abl inhibitor hybrids as next generation ALS therapeuticsPrincipal Investigator

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Structure optimization of compounds to confine HIV in a cell and induce apoptosis aiming at drugsPrincipal Investigator

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Development of a method to induce apoptosis by HIV locked in a cellPrincipal Investigator

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Elucidation of SAMHD1-independent function of HIV/SIV VpxPrincipal Investigator

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Identification and functional analysis of anti-HIV host factor in macrophagesPrincipal Investigator

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Regulation of HIV replication by inositol phosphatesPrincipal Investigator

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FUJITA MIKAKO 藤田美歌子

FUJITA Mikako 藤田美歌子