Ohtsuka Kazuo 大塚和朗

Researcher Number	00338443
Other IDs
Affiliation (Current)	2025: 東京科学大学, 東京科学大学病院, 准教授 2025: 昭和医科大学, 医学部, 兼任講師
Affiliation (based on the past Project Information) *help	2023: 東京医科歯科大学, 東京医科歯科大学病院, 准教授 2017 – 2022: 東京医科歯科大学, 医学部附属病院, 准教授 2014 – 2015: 東京医科歯科大学, 医学部附属病院, 特別診療教授 2013: 東京医科歯科大学, 医学部附属病院, 教授
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 58010:Medical management and medical sociology-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator クローン病 / オルガノイド / シングルセル解析 / 幹細胞 / ヒト体外IBDモデル / 小腸 / 体外疾患モデル / 粘膜治癒 / 分子マーカー / 炎症応答評価 … More / 病態解明 / 再燃予測 / 小腸オルガノイド / バルーン内視鏡 / 網羅的遺伝子解析 / 小腸がん … More Except Principal Investigator アドヒアランス / 行動変容 / 人工知能 / モバイルヘルスケア / 潰瘍性大腸炎 / 病変部由来オルガノイド / 炎症修飾 / 好発部位 / 病変部特異的因子 / 炎症性腸疾患 Less

クローン病小腸病変における区域依存的幹細胞特性の解析と再生医療への応用Principal Investigator
- Principal Investigator
  
  大塚和朗
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Development and validation of a mobile health system to promote behavior change in patients with ulcerative colitis.
- Principal Investigator
  
  前田康晴
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Showa University
Elucidation of mucosal healing mechanisms through the construction of a human Crohn 's disease modelPrincipal Investigator
- Principal Investigator
  
  Kazuo Ohtsuka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
The elucidation of common pathogenesis specialized in the lesion of IBD
- Principal Investigator
  
  Takenaka Kento
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Development of the prediction system for relapse in Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  Ohtsuka Kazuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Comprehensive gene analysis of small intestinal cancer tumorPrincipal Investigator
- Principal Investigator
  
  Ohtsuka Kazuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn’s disease activity confirmed by balloon-assisted enteroscopy2024
- Author(s)
  Kawamoto Ami、Takenaka Kento、Hibiya Shuji、Kitazume Yoshio、Shimizu Hiromichi、Fujii Toshimitsu、Saito Eiko、Ohtsuka Kazuo、Okamoto Ryuichi
- Journal Title
  
  Intestinal Research
  
  Volume: 22 Issue: 1 Pages: 65-74
- DOI
  10.5217/ir.2023.00092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07352, KAKENHI-PROJECT-23K07413, KAKENHI-PROJECT-23K27579
[Journal Article] Motility Mapping Quantification Using the Classical Optical Flow Algorithm for Small Bowel Crohn’s Disease: Comparison with Balloon-assisted Enteroscopy Findings2023
- Author(s)
  Kitazume Yoshio、Takenaka Kento、Ohtsuka Kazuo、Ozawa Yasuo、Kimura Koichiro、Watanabe Ryosuke、Tsuchiya Junichi、Fujii Toshimitsu、Nagahori Masakazu、Watanabe Mamoru、Tateishi Ukihide
- Journal Title
  
  MRMS
  
  Volume: 22 Issue: 3 Pages: 325-334
- DOI
  10.2463/mrms.mp.2021-0037
- ISSN
  1347-3182, 1880-2206
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07721, KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-23K07352
[Journal Article] Transmural remission characterized by high biologic concentrations demonstrates better prognosis in Crohn's disease2022
- Author(s)
  Kento Takenaka, Ami Kawamoto, Yoshio Kitazume, Toshimitsu Fujii, Yumi Udagawa, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto
- Journal Title
  
  J Crohns Colitis.
  
  Volume: - Issue: 6 Pages: 855-862
- DOI
  10.1093/ecco-jcc/jjac185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-23K07352, KAKENHI-PROJECT-23K07413, KAKENHI-PROJECT-23K27579
[Journal Article] Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study2022
- Author(s)
  Kento Takenaka, Toshimitsu Fujii, Ami Kawamoto, Kohei Suzuki, Hiromichi Shimizu, Chiaki Maeyashiki, Osamu Yamaji, Maiko Motobayashi, Akira Igarashi, Ryoichi Hanazawa, Shuji Hibiya, Masakazu Nagahori, Eiko Saito, Ryuichi Okamoto, Kazuo Ohtsuka, Mamoru Watanabe
- Journal Title
  
  Lancet Gastroenterol Hepatol
  
  Volume: 7 Issue: 3 Pages: 230-237
- DOI
  10.1016/s2468-1253(21)00372-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K07977, KAKENHI-PROJECT-21K15991, KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-21K15918, KAKENHI-PROJECT-21K15992
[Journal Article] Systematic review of artificial <scp>intelligence‐based</scp> image diagnosis for inflammatory bowel disease2022
- Author(s)
  Kawamoto Ami、Takenaka Kento、Okamoto Ryuichi、Watanabe Mamoru、Ohtsuka Kazuo
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 34 Issue: 7 Pages: 1311-1319
- DOI
  10.1111/den.14334
- Data Source
  KAKENHI-PROJECT-20K08378
[Journal Article] Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease2022
- Author(s)
  Kento Takenaka, Yoshio Kitazume, Ami Kawamoto, Toshimitsu Fujii, Yumi Udagawa, Ryosuke Wanatabe, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Hiroyuki Sato, Akihiro Hirakawa, Mamoru Watanabe, Ryuichi Okamoto
- Journal Title
  
  Am J Gastroenterol.
  
  Volume: - Issue: 6 Pages: 1028-1035
- DOI
  10.14309/ajg.0000000000002127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K15991, KAKENHI-PROJECT-23K07352, KAKENHI-PROJECT-23K07413, KAKENHI-PROJECT-23K27579
[Journal Article] Higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease2021
- Author(s)
  Kento Takenaka, Ami Kawamoto, Shuji Hibiya, Kohei Suzuki, Toshimitsu Fujii, Maiko Motobayashi, Hiromichi Shimizu, Masakazu Nagahori, Eiko Saito, Ryuichi Okamoto, Mamoru Watanabe, Kazuo Ohtsuka
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 54 Issue: 8 Pages: 1052-1060
- DOI
  10.1111/apt.16551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K15991
[Journal Article] Serum leucine-rich α-2 glycoprotein; a novel biomarker for small bowel mucosal activity in Crohn’s Disease.2021
- Author(s)
  Kawamoto T, Takenaka K, Hibiya S, Ohtsuka K, Okamoto R, Watanabe M
- Journal Title
  
  Clin Gastroenterol Hepatol.
  
  Volume: 20 Issue: 5 Pages: e1196-e1200
- DOI
  10.1016/j.cgh.2021.06.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-21K15918, KAKENHI-PROJECT-21K15991
[Journal Article] Deep Neural Network Accurately Predicts Prognosis of Ulcerative Colitis Using Endoscopic Images2021
- Author(s)
  Kento Takenaka, Kazuo Ohtsuka, Toshimitsu Fujii, Shiori Oshima, Ryuichi Okamoto, Mamoru Watanabe
- Journal Title
  
  Gastroenterology
  
  Volume: 160 Issue: 6 Pages: 2175-2177
- DOI
  10.1053/j.gastro.2021.01.210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K07977
[Journal Article] Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus2021
- Author(s)
  Hiromichi Shimizu, Toshimitsu Fujii, Kenji Kinoshita, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 21 Issue: 1 Pages: 494-494
- DOI
  10.1186/s12876-021-02043-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K15991, KAKENHI-PROJECT-21K15992
[Journal Article] Combined endocytoscopy with pit pattern diagnosis in ulcerative colitis‐associated neoplasia: Pilot study2021
- Author(s)
  Kudo Shin‐ei、Maeda Yasuharu、Okumura Taishi、Matsudaira Shingo、Ishigaki Tomoyuki、Sasanuma Seiko、Mori Yuichi、Kudo Toyoki、Hayashi Takemasa、Wakamura Kunihiko、Miyachi Hideyuki、Baba Toshiyuki、Ohtsuka Kazuo
- Journal Title
  
  Digestive Endoscopy
  
  Volume: - Issue: 1 Pages: 133-143
- DOI
  10.1111/den.13964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-20K17002
[Journal Article] Crohn disease: magnetic resonance enterocolonography features of endoscopic ulcer stages reclassified with the healing process and the relationships to prognoses2021
- Author(s)
  Yoshio Kitazume, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Yusuke Ogihara, Tomoyuki Fujioka, Junichi Tsuchiya, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi
- Journal Title
  
  Jpn J Radiol
  
  Volume: 39 Issue: 5 Pages: 459-476
- DOI
  10.1007/s11604-020-01082-5
- NAID
  210000160272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378
[Journal Article] Colonic strictures mimicking Crohn’s disease2021
- Author(s)
  Takenaka Kento、Kimura Maiko、Ohtsuka Kazuo
- Journal Title
  
  Gut
  
  Volume: 70 Issue: 2 Pages: 233-387
- DOI
  10.1136/gutjnl-2019-320172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08378
[Journal Article] Development and validation of a deep neural network for accurate evaluation of endoscopic images from patients with ulcerative colitis.2020
- Author(s)
  Kento Takenaka , Kazuo Ohtsuka , Toshimitsu Fujii , Mariko Negi , Kohei Suzuki , Hiromichi Shimizu , Shiori Oshima , Shintaro Akiyama , Maiko Motobayashi , Masakazu Nagahori , Eiko Saito , Katsuyoshi Matsuoka , Mamoru Watanabe
- Journal Title
  
  Gastroenterology
  
  Volume: Epub ahead of print Issue: 8 Pages: 2150-2157
- DOI
  10.1053/j.gastro.2020.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K07902
[Journal Article] Objective evaluation for treat to target in Crohn’s disease2020
- Author(s)
  Takenaka Kento、Kitazume Yoshio、Fujii Toshimitsu、Tsuchiya Kiichiro、Watanabe Mamoru、Ohtsuka Kazuo
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 55 Issue: 6 Pages: 579-587
- DOI
  10.1007/s00535-020-01678-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-18K07902
[Journal Article] High b-value computed diffusion-weighted imaging for differentiating bowel inflammation in Crohn's disease2020
- Author(s)
  Yoshio Kitazume, Junichi Tsuchiya, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Ryosuke Watanabe, Tomoyuki Fujioka, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi
- Journal Title
  
  Eur J Radiol
  
  Volume: 133 Pages: 109362-109362
- DOI
  10.1016/j.ejrad.2020.109362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-19H01050
[Journal Article] Crohn Disease: A 5-Point MR Enterocolonography Classification Using Enteroscopic Findings2019
- Author(s)
  Kitazume Yoshio、Fujioka Tomoyuki、Takenaka Kento、Oyama Jun、Ohtsuka Kazuo、Fujii Toshimitsu、Tateisi Ukihide
- Journal Title
  
  American Journal of Roentgenology
  
  Volume: 212 Issue: 1 Pages: 67-76
- DOI
  10.2214/ajr.17.18897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-15K19778, KAKENHI-PROJECT-17K09372
[Journal Article] Small Bowel Healing Detected by Endoscopy in Patients With Crohn’s Disease After Treatment With Antibodies Against Tumor Necrosis Factor2019
- Author(s)
  Takenaka Kento、Fujii Toshimitsu、Suzuki Kohei、Shimizu Hiromichi、Motobayashi Maiko、Hibiya Shuji、Saito Eiko、Nagahori Masakazu、Watanabe Mamoru、Ohtsuka Kazuo
- Journal Title
  
  Clinical Gastroenterology and Hepatology
  
  Volume: inpress Issue: 7 Pages: 1545-1552
- DOI
  10.1016/j.cgh.2019.08.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-19K17484, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19K17425
[Journal Article] Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients2018
- Author(s)
  Kawamoto Ami、Nagata Sayaka、Anzai Sho、Takahashi Junichi、Kawai Mao、Hama Minami、Nogawa Daichi、Yamamoto Kouhei、Kuno Reiko、Suzuki Kohei、Shimizu Hiromichi、Hiraguri Yui、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Kitagawa Masanobu、Okamoto Ryuichi、Watanabe Mamoru
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 13 Issue: 4 Pages: 495-509
- DOI
  10.1093/ecco-jcc/jjy180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-18K15774, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-18H02791
[Journal Article] Predictors of mucosal healing during induction therapy in patients with acute moderate‐to‐severe ulcerative colitis2018
- Author(s)
  Motobayashi Maiko、Matsuoka Katsuyoshi、Takenaka Kento、Fujii Toshimitsu、Nagahori Masakazu、Ohtsuka Kazuo、Iwamoto Fumihiko、Tsuchiya Kiichiro、Negi Mariko、Eishi Yoshinobu、Watanabe Mamoru
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: in press Issue: 6 Pages: 1004-1010
- DOI
  10.1111/jgh.14565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19K08438
[Journal Article] Prediction of disease activity of Crohn's disease through fecal calprotectin evaluated by balloon‐assisted endoscopy2018
- Author(s)
  Iwamoto Fumihiko、Matsuoka Katsuyoshi、Motobayashi Maiko、Takenaka Kento、Kuno Toru、Tanaka Keisuke、Tsukui Yuya、Kobayashi Shoji、Yoshida Takashi、Fujii Toshimitsu、Saito Eiko、Yamaguchi Tatsuya、Nagahori Masakazu、Sato Tadashi、Ohtsuka Kazuo、Enomoto Nobuyuki、Watanabe Mamoru
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 33 Issue: 12 Pages: 1984-1989
- DOI
  10.1111/jgh.14310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K07902
[Journal Article] Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties2018
- Author(s)
  Suzuki Kohei、Murano Tatsuro、Shimizu Hiromichi、Ito Go、Nakata Toru、Fujii Satoru、Ishibashi Fumiaki、Kawamoto Ami、Anzai Sho、Kuno Reiko、Kuwabara Konomi、Takahashi Junichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 9 Pages: 1035-1047
- DOI
  10.1007/s00535-018-1437-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-16K09302, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674
[Journal Article] Endoscopic features and genetic background of inflammatory bowel disease complicated with Takayasu arteritis.2017
- Author(s)
  Akiyama S, Fujii T, Matsuoka K, Yusuke E, Negi M, Takenaka K, Nagahori M, Ohtsuka K, Isobe M, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 32 Issue: 5 Pages: 1011-1017
- DOI
  10.1111/jgh.13640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-26670399, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-17K07251
[Journal Article] Chronic Enteropathy Associated With SLCO2A1 Gene [CEAS]-Characterisation of an Enteric Disorder to be Considered in the Differential Diagnosis of Crohn’s Disease2017
- Author(s)
  Hosoe Naoki、Ohmiya Naoki、Yano Tomonori、Okita Yoshiki、Araki Toshimitsu、Saruta Masayuki、Ohtsuka Kazuo、CEAS Atlas Group
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 11 Issue: 10 Pages: 1277-1281
- DOI
  10.1093/ecco-jcc/jjx068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-15H04811
[Journal Article] Utility of Magnetic Resonance Enterography For Small Bowel Endoscopic Healing in Patients With Crohn’s Disease2017
- Author(s)
  Takenaka Kento、Ohtsuka Kazuo、Kitazume Yoshio、Matsuoka Katsuyoshi、Nagahori Masakazu、Fujii Toshimitsu、Saito Eiko、Kimura Maiko、Fujioka Tomoyuki、Watanabe Mamoru
- Journal Title
  
  The American Journal of Gastroenterology
  
  Volume: 113 Issue: 2 Pages: 283-294
- DOI
  10.1038/ajg.2017.464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372
[Journal Article] Reduced human α-defensin 6 in non-inflamed jejunal tissue of Crohn’s disease patients2016
- Author(s)
  Hayashi R , Tsuchiya K, Okamoto R,Watanabe M,et al
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 22 Issue: 5 Pages: 1119-28
- DOI
  10.1097/mib.0000000000000707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16K09302
[Journal Article] Epithelial Nuclear Factor-kB Activation in Inflammatory Bowel Diseases and Colitis-Associated Carcinogenesis. "2016
- Author(s)
  Nagaishi T,Watabe T,Jose N, Tokai A, Fujii T, Matsuoka K, Nagahori M, Ohtsuka K
- Journal Title
  
  Digestion
  
  Volume: 93 Issue: 1 Pages: 40-46
- DOI
  10.1159/000441670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-15K15288, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-26221307
[Journal Article] Tacrolimus for the Treatment of Ulcerative Colitis.2015
- Author(s)
  Matsuoka K, Saito E, Fujii T, Takenaka K, Kimura M, Nagahori M, Ohtsuka K, Watanabe M.
- Journal Title
  
  Intest Res.
  
  Volume: 13 Issue: 3 Pages: 219-226
- DOI
  10.5217/ir.2015.13.3.219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-25461031
[Journal Article] Correlation of the Endoscopic and Magnetic Resonance Scoring Systems in the Deep Small Intestine in Crohn's Disease.2015
- Author(s)
  Takenaka K, Ohtsuka K, Kitazume Y, Nagahori M, Fujii T, Saito E, Fujioka T, Matsuoka K, Naganuma M, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: 21 Issue: 8 Pages: 1832-1838
- DOI
  10.1097/mib.0000000000000449
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-25461031
[Journal Article] Advancing magnetic resonance imaging in Crohn's disease.2014
- Author(s)
  Fujii T, Naganuma M, Kitazume Y, Saito E, Nagahori M, Ohtsuka K, Watanabe M.
- Journal Title
  
  Digestion
  
  Volume: 89 Issue: 1 Pages: 24-30
- DOI
  10.1159/000356210
- NAID
  130005084744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-26460963
[Journal Article] Comparison of Magnetic Resonance and Balloon Enteroscopic Examination of Deep Small Intestine in Patients with Crohn's Disease.2014
- Author(s)
  Takenaka K, Ohtsuka K,Watanabe M et al
- Journal Title
  
  Gastroenterology
  
  Volume: [Epub ahead of print] Issue: 2 Pages: 334-342
- DOI
  10.1053/j.gastro.2014.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-26460963
[Journal Article] Carbon dioxide insufflation improves the intubation depth and total enteroscopy rate in single-balloon enteroscopy: a randomised, controlled, double-blind trial2014
- Author(s)
  Li X, Zhao YJ, Dai J, Li XB, Xue HB, Zhang Y, Xiong GS, Ohtsuka K, Gao YJ, Liu Q, Song Y, Fang JY, Ge ZZ
- Journal Title
  
  Gut
  
  Volume: in press Issue: 10 Pages: 1560-1565
- DOI
  10.1136/gutjnl-2013-306069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461031
[Journal Article] Efficacy of salvage therapy and its effect on operative outcomes in patients with ulcerative colitis.2014
- Author(s)
  Saito E, Nagahori M, Fujii T, Otsuka K, Watanabe M
- Journal Title
  
  Digestion
  
  Volume: 89 Issue: 1 Pages: 55-60
- DOI
  10.1159/000356221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-26460963
[Journal Article] Magnetically Guided Capsule Versus Conventional Gastroscopy for Upper Abdominal Complaints: A Prospective Blinded Study2014
- Author(s)
  Denzer UW, Rosch T, Hoytat B, Abdel-Hamid M, Hebuterne X, Vanbiervielt G, Filippi J, Ogata H, Hosoe N, Ohtsuka K, Ogata N, Ikeda K, Aihara H, Kudo SE, Tajiri H, Treszl A, Wegscheider K, Greff M, Rey JF
- Journal Title
  
  J Clin Gastroenterol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461031
[Journal Article] Lineage-specific expression of Bestrophin-2 and Bestrophin-4 in human intestinal epithelial cells.2013
- Author(s)
  Ito G, Okamoto R, Nakamura T, Watanabe M et al
- Journal Title
  
  PloS One.
  
  Volume: 8 Issue: 11 Pages: e79693-e79693
- DOI
  10.1371/journal.pone.0079693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524
[Journal Article] Endocytoscopy provides an in vivo virtual histopathological diagnosis of Whipple's disease.2013
- Author(s)
  Watanabe D, Kudo SE, Hayashi S, Mori Y, Kodama K, Wakamura K, Miyachi H, Yamamura F, Ohtsuka K, Mikogami T, Kimura S, Fukuchi K, Ikehara N.
- Journal Title
  
  Endoscopy
  
  Volume: 45 Issue: S 02 Pages: 143-144
- DOI
  10.1055/s-0032-1326276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] クローン病の小腸病変モニタリングにおけるバイオマーカーの有用性2024
- Author(s)
  田村皓子、河本亜美、竹中健人、小林桜子、森川亮、日比谷秀爾、清水寛路、藤井俊光、齊藤詠子、長堀正和、大塚和朗、岡本隆一
- Organizer
  第20回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-23K07352
[Presentation] クローン病肛門病変の生物学的製剤に対する内視鏡評価2023
- Author(s)
  4)竹中健人、河本亜美、藤井俊光、日比谷秀爾、田村皓子、森川亮、小林桜子、清水寛路、齊藤詠子、長堀正和、大塚和朗、岡本隆一
- Organizer
  第14回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07352
[Presentation] COMBINING LEUCINE-RICH ALPHA-2 GLYCOPROTEIN AND FAECAL BIOMARKERS FOR ACCURATE MONITORING OF SMALL BOWEL ACTIVITY IN CROHN’S DISEASE2023
- Author(s)
  A. Kawamoto, K. Takenaka, S. Hibiya, Y. Kitazume, K. Ito, H. Shimizu, T. Fujii, E. Saito, K. Ohtsuka, R. Okamoto
- Organizer
  UEG Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07352
[Presentation] 生物学的製剤によるクローン病狭窄性病変の変化2023
- Author(s)
  竹中健人、河本亜美、日比谷秀爾、大塚和朗、岡本隆一
- Organizer
  第117回日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-23K07352
[Presentation] Intolerance to 5-aminosalicylate is a risk of poor prognosis in Ulcerative colitis patients.2020
- Author(s)
  Toshimitsu Fujii, Shuji Hibiya, Chiaki Maeyashiki, Eiko Saito, Kento Takenaka, Maiko Motobayashi, Hiromichi Shimizu, Masakazu Nagahori, Kazuo Ohtsuka, Masayuki Kurosaki, Tsunehito Yauchi, Mamoru Watanabe.
- Organizer
  ECCO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] Intolerance to 5-aminosalicylate is a risk of poor prognosis in Ulcerative colitis patients2020
- Author(s)
  Toshimitsu Fujii, Shuji Hibiya, Chiaki Maeyashiki, Eiko Saito, Kento Takenaka, Maiko Motobayashi, Hiromichi Shimizu, Masakazu Nagahori, Kazuo Ohtsuka, Masayuki Kurosaki, Tsunehito Yauchi, Mamoru Watanabe.
- Organizer
  ECCO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病小腸病変に対するアプローチ.2019
- Author(s)
  竹中健人、大塚和朗、渡辺守.
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病小腸病変に対するアプローチ2019
- Author(s)
  竹中健人、大塚和朗、渡辺守.
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] Small bowel endoscopic healing of Crohn’s disease treated with anti-TNF antibodies.2019
- Author(s)
  Kento Takenaka, Kazuo Ohtsuka, Toshimitsu Fujii, Kohei Suzuki, Hiromichi Shimizu, Maiko Motobayashi, Shuji Hibiya, Eiko Saito, Masakazu Nagahori, Mamoru Watanabe.
- Organizer
  AOCC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] 当院でのバルーン内視鏡によるクローン病小腸病変評価方法2018
- Author(s)
  竹中健人、大塚和朗、渡辺　守.
- Organizer
  日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] Small bowel mucosal healing of Crohn’s disease treated with anti-TNF antibodies.2018
- Author(s)
  Takenaka K, Ohtsuka K, Fujii T, Nagahori M, Saito E, Motobayashi M, Suzuki K, Watanabe M
- Organizer
  FALK symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] Utility of Magnetic Resonance Evaluation for Small Bowel Endoscopic Healing in Patients with Crohn’s Disease.2018
- Author(s)
  Takenaka K, Ohtsuka K, Kitazume Y, Fujii T, Matsuoka K, Kimura M, Nagahori M, Watanabe M.
- Organizer
  UEGW2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] 当院でのバルーン内視鏡によるクローン病小腸病変評価方法.2018
- Author(s)
  竹中健人、大塚和朗、渡辺　守.
- Organizer
  第95 回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病における小腸内視鏡的重症度の検討2018
- Author(s)
  竹中健人、大塚和朗、渡辺　守
- Organizer
  JDDW2018
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] Small bowel mucosal healing of Crohn’s disease treated with anti-TNF antibodies.2018
- Author(s)
  Takenaka K, Ohtsuka K, Fujii T, Nagahori M, Saito E, Motobayashi M, Suzuki K, Watanabe M.
- Organizer
  FALK symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病における小腸内視鏡的重症度の検討.2018
- Author(s)
  竹中健人、大塚和朗、渡辺　守
- Organizer
  JDDW2018
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] Usefulness of single-balloon enteroscopy: from a single center 990 experiences.2018
- Author(s)
  Ohtsuka K, Takenaka K, Suzuki K, Fujii T, Nagahori M, Matsuoka K, Saito E, Katsukura N, Fukuda M, Araki A, Watanabe M
- Organizer
  DDW2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] Usefulness of single-balloon enteroscopy: from a single center 990 experiences.2018
- Author(s)
  Ohtsuka K, Takenaka K, Suzuki K, Fujii T, Nagahori M, Matsuoka K, Saito E, Katsukura N, Fukuda M, Araki A, Watanabe M
- Organizer
  DDW2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07902
[Presentation] Simplified MR enterocolonography Classification Based on Endoscopic Findings for Activity Assessment of Crohn’s Disease.2018
- Author(s)
  Fujii T, Kitazume Y, Takenaka K, Kimura M, Saito E, Matsuoka K, Nagahori M, Ohtsuka K, Watanabe M.
- Organizer
  UEGW2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] 当院でのクローン病に対するシングルバルーン内視鏡2018
- Author(s)
  鈴木康平、大塚和朗、渡辺　守
- Organizer
  JDDW2018
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] Magnetic resonance evaluation for small bowel endoscopic remission in patients with crohn’s disease2017
- Author(s)
  Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Katsuyoshi Matsuoka, Toshimitsu Fujii, Masakazu Nagahori, Maiko Kimura, Mamoru Watanabe.
- Organizer
  AOCC2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病活動性モニタリングにおける小腸内視鏡とMREの役割2017
- Author(s)
  大塚和朗、竹中健人、渡辺　守.
- Organizer
  JDDW 2017
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] The 5-point MR enterocolonography classification based on endoscopic findings for activity assessment of Crohn's disease.2017
- Author(s)
  Fujii T, Kitazume Y, Takenaka K, Kimura M, Matsuoka K, Nagahori M, Ohtsuka K, Watanabe M.
- Organizer
  AOCC2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病評価における小腸内視鏡の有用性と限界.2017
- Author(s)
  竹中健人、大塚和朗、北詰良雄、鈴木康平、木村麻衣子、藤岡友之、福田将義、藤井俊光、齋藤詠子、松岡克善、長堀正和、渡辺　守
- Organizer
  第55回日本小腸学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] Magnetic resonance enterography for small bowel mucosal healing in patients with Crohn’s disease.2017
- Author(s)
  Takenaka K, Ohtsuka K, Kitazume Y, Matsuoka K, Fujii T, Nagahori M, Kimura M, Watanabe M.
- Organizer
  APDW2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病小腸病変に対するMRI によるEndoscopic remission 評価.2017
- Author(s)
  竹中健人、大塚和朗、渡辺　守.
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] クローン病におけるシングルバルーン内視鏡所見と患者予後との関係に関する検討.2017
- Author(s)
  竹中健人、大塚和朗、渡辺　守.
- Organizer
  第93回日本消化器内視鏡学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09370
[Presentation] 小腸内視鏡の適応と手技2016
- Author(s)
  大塚和朗
- Organizer
  第12回日本消化管学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-02-26
- Invited
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] クローン病小腸狭窄に対するMREC所見と内視鏡下バルーン拡張術の手術回避に対する検討2016
- Author(s)
  竹中健人、大塚和朗、北詰良雄、福田将義、野崎賢吾、渡辺守、岩本史光、木村麻衣子、藤井俊光、松岡克善、長堀正和
- Organizer
  第12回日本消化管学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] クローン病小腸病変に対するバルーン内視鏡およびMRI所見.2015
- Author(s)
  竹中健人、大塚和朗、北詰良雄、福田将義、野崎賢吾、岩本史光、木村麻衣子、藤井俊光、松岡克善、長堀正和、渡辺守
- Organizer
  第53回小腸研究会
- Place of Presentation
  いわて県民情報交流センター（アイーナ）（岩手県盛岡市）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] クローン病治療における生物学的製剤と内視鏡治療・外科手術2015
- Author(s)
  大塚和朗、長堀正和、渡辺守
- Organizer
  JDDW2015
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] 潰瘍性大腸炎関連腫瘍の内視鏡診断と治療2015
- Author(s)
  大塚和朗、和田祥城、渡辺　守
- Organizer
  第89回日本消化器内視鏡学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] 当院における生物学的製剤の長期予後とクローン画像評価の重要性.2015
- Author(s)
  竹中健人、大塚和朗、渡辺守
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25461031
[Presentation] カプセル内視鏡の未来ー小腸、大腸、そして上部へー2013
- Author(s)
  大塚和朗　荒木昭博　渡辺守
- Organizer
  第6回日本カプセル内視鏡学会
- Place of Presentation
  東京、都市センターホテル
- Invited
- Data Source
  KAKENHI-PROJECT-25461031

1. TSUCHIYA Kiichiro (40376786)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. WATANABE Mamoru (10175127)

# of Collaborated Projects: 2 results

# of Collaborated Products: 40 results
3. Takenaka Kento (10783368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 岡本隆一 (50451935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 前田康晴 (30595616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 藤井俊光

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
7. 齊藤詠子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
8. 長堀正和

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 中村哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 永石宇治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohtsuka Kazuo 大塚 和朗

Research Projects

Research Products

Co-Researchers

クローン病小腸病変における区域依存的幹細胞特性の解析と再生医療への応用Principal Investigator

Principal Investigator

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Research Institution

Development and validation of a mobile health system to promote behavior change in patients with ulcerative colitis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mucosal healing mechanisms through the construction of a human Crohn 's disease modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of common pathogenesis specialized in the lesion of IBD

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the prediction system for relapse in Crohn's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Comprehensive gene analysis of small intestinal cancer tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Journal Article] Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn’s disease activity confirmed by balloon-assisted enteroscopy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Motility Mapping Quantification Using the Classical Optical Flow Algorithm for Small Bowel Crohn’s Disease: Comparison with Balloon-assisted Enteroscopy Findings2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Transmural remission characterized by high biologic concentrations demonstrates better prognosis in Crohn's disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic review of artificial <scp>intelligence‐based</scp> image diagnosis for inflammatory bowel disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum leucine-rich α-2 glycoprotein; a novel biomarker for small bowel mucosal activity in Crohn’s Disease.2021

Author(s)

Journal Title

Ohtsuka Kazuo 大塚和朗