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Tsuchiya Kiichiro  土屋 輝一郎

… Alternative Names

TSUCHIYA Kiichirou  土屋 輝一郎

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Researcher Number 40376786
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-1977-8707
Affiliation (Current) 2022: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help 2021 – 2022: 筑波大学, 医学医療系, 教授
2015 – 2020: 東京医科歯科大学, 医学部附属病院, 准教授
2015: 東京医科歯科大学, 医学部附属病院消化器内科, 准教授
2015: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授
2013 – 2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座准教授 … More
2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座講師
2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 講師
2012: 東京医科歯科大学, 医歯学総合研究科, 講師
2010 – 2011: Tokyo Medical and Dental University, 医学部附属病院, 講師
2009: Tokyo Medical and Dental University, 医学部・附属病院, 講師
2008: Tokyo Medical and Dental University, 医学部附属病院, 講師
2007: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教
2005 – 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助手
2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Biological Sciences / Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Except Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Biological Sciences / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
Atoh1 / Hath1 / 癌幹細胞 / 小腸 / 炎症性腸疾患 / シグナルスパイラル / 分化制御 / 標的遺伝子 / パネート細胞 / 抗菌物質 … More / FGFシグナル / TCF4 / HD6 / クローン病 / 小腸上皮細胞 / 炎症発がん / 大腸上皮培養 / がん幹細胞可視化 / 粘液産生がん / GSK3 / TNFα / 蛋白安定機構 / サイトカイン / 長期自然免疫応答モデル / 大腸初代培養 / 酸化ストレス / 炎症発癌モデル / 幹細胞可視化 / ニッチ形成 / Math1 / 杯細胞分化 / 転写因子 / 腸管免疫 / 腸管分化 / 杯細胞 / Wntシグナル / 蛋白分解 / Wnt signal / Transcription / Intestine / 1幹細胞可視化 / Lgr5プロモーター / 1幹細胞動態 / 炎症発癌 / 自然免疫応答 / 持続炎症刺激モデル / 持続炎症 / 位置運命決定因子 / 病変好発部位 / 疾患感受性 / 疾患好発部位 / オルガノイド / 腸上皮化生 / IPMN / 腸上皮形質 / スキルスがん / スキルス癌 / ヒト体外モデル / 炎症塑性 / 塑性リセット … More
Except Principal Investigator
炎症性腸疾患 / Notchシグナル / Notch / クローン病 / Atoh1 / Wntシグナル / シグナル伝達 / Wnt / Hath1 / IL-7 / 再生医学 / トランスレーショナルリサーチ / 細胞内シグナル伝達 / マッピング生検 / バルーン内視鏡 / 腸管分化 / 転写因子 / iPS細胞 / 再生医療 / transdifferentiation / 杯細胞分化 / Interferon Regulatory Factor (IRF) / 免疫学 / 生体分子 / IL-7レセプター / Interferon Regulatory Factor(IRF) / 消化管粘膜免疫制御 / 免疫制御療法 / 腸管再生 / CEACAM1 / リンパ球 / 粘膜免疫 / サイトカイン / ダブルバルーン内視鏡 / DBE / 小腸生検 / 小腸培養 / 杯細胞 / 小腸内視鏡 / 生検検体 / 腸管上皮 / オルガノイド / ニッチ / 幹細胞ニッチ / 潜在的炎症 / 小腸がん / 網羅的遺伝子解析 / 腸内環境 / 共培養 / 幹細胞機能評価 / 疑似モデル構築 / 全身制御 / 発生・分化 / ユビキチン-プロテアソーム / Hath-1 / Differentiation / Regenerative medicine / Translational research / Signal transduction / 慢性大腸炎 / 大腸上皮再生 / 幹細胞 / Chronic colitis / Regeneration / Stem Cell / HD6 / 抗菌物質 / 粘膜バリア能 / 粘膜防御 / ナノネット / 小腸オルガノイド / 再燃予測 / 病態解明 / 炎症応答評価 / 分子マーカー / 病変部特異的因子 / 好発部位 / 炎症修飾 / 病変部由来オルガノイド / ヒトiPS細胞 / 胆管癌 / 疾患モデル / 胆管上皮細胞 / 胆汁 / 発癌機序 / 臓器間制御 / ヒトオルガノイド / iPS細胞複合臓器体外モデル / 臓器間制御機構 / 臓器共培養 / 複合臓器体外モデル / 小腸病変 / 体外疾患モデル / 小腸 / ヒト体外IBDモデル / 粘膜治癒 / 腸再生医療 / 組織エンジニアリング / 小腸移植 / マルチ作用点薬剤 / 腫瘍抑制作用機序 / レゴラフェニブ / 炎症発癌モデル / 回腸嚢炎 / 回腸嚢内視鏡表現型 / 小腸粘膜大腸化機構 / IBD人工モデル / 上皮障害度 / 非アルコール性脂肪性肝疾患 / 非アルコール性脂肪性肝炎 / 肝癌 / p62 / 脂肪酸代謝 / 免疫チェックポイント阻害薬 / 免疫関連有害事象 / irAE腸炎 Less
  • Research Projects

    (36 results)
  • Research Products

    (345 results)
  • Co-Researchers

    (82 People)
  •  Development of technology for in vivo intestinal engineering by transplantation of organoids after epithelial removal by using newly-synthesized chelating agents.

    • Principal Investigator
      中村 哲也
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Juntendo University
  •  オルガノイド技術を用いた大腸癌に対するレゴラフェニブ効果・耐性因子の同定

    • Principal Investigator
      森脇 俊和
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      University of Tsukuba
  •  独自に構築した回腸嚢炎内視鏡的サブタイプの層別解析による病態解明

    • Principal Investigator
      秋山 慎太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      University of Tsukuba
  •  炎症性腸疾患における腸管上皮障害評価システムの構築

    • Principal Investigator
      小林 真理子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      University of Tsukuba
  •  肝細胞のp62は如何にしてNASHを防御するか?- 基礎と臨床両面からの解析

    • Principal Investigator
      福田 邦明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      University of Tsukuba
  •  IBD上皮病態を基軸とした免疫チェックポイント阻害薬関連腸炎の病態解明

    • Principal Investigator
      山田 武史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba
  •  組織学的治癒を目指したIBD病態リセット機構の解明Principal Investigator

    • Principal Investigator
      土屋 輝一郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      University of Tsukuba
  •  炎症性腸疾患における小腸難治化機構の解明

    • Principal Investigator
      竹中 健人
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒトクローン病モデル構築による粘膜治癒機構の解明

    • Principal Investigator
      大塚 和朗
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒトiPS細胞由来胆管細胞培養系を用いた胆管癌における新規発癌機序の解明

    • Principal Investigator
      小林 正典
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒト体外複合臓器モデルによる生体維持機構解析

    • Principal Investigator
      渡辺 守
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  The elucidation of common pathogenesis specialized in the lesion of IBD

    • Principal Investigator
      Takenaka Kento
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  The regulation of human organ structure by position fate genesPrincipal Investigator

    • Principal Investigator
      Tsuchiya Kiichiro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  The mechanism of malignant potential in digestive cancers based on intestinal metaplasiaPrincipal Investigator

    • Principal Investigator
      Tsuchiya Kiichiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of the prediction system for relapse in Crohn's disease

    • Principal Investigator
      Ohtsuka Kazuo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  ナノネット粘膜防御によるクローン病新規治療開発

    • Principal Investigator
      荒木 昭博
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Single cell imaging in human intestinal stem cellPrincipal Investigator

    • Principal Investigator
      Tsuchiya Kiichiro
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Inflammation related carcinogenesis by spiral cell transformation using in vitro chronic colitis modelPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Kiichiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  The elucidation of homeostasis regulated by intestinal epithelial stem cells

    • Principal Investigator
      Watanabe Mamoru
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  腸管上皮細胞における自然免疫応答スパイラル機構解析Principal Investigator

    • Principal Investigator
      土屋 輝一郎
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒト大腸上皮培養による大腸癌幹細胞の分化破綻機構解析Principal Investigator

    • Principal Investigator
      土屋 輝一郎
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of colitic mucosa repair therapy by the induction of regeneration-specific stem cell niche formation

    • Principal Investigator
      Okamoto Ryuichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of the pathogenesis in CD using mapping biopsy from entire small intestine

    • Principal Investigator
      Araki Akihiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Comprehensive gene analysis of small intestinal cancer tumor

    • Principal Investigator
      Ohtsuka Kazuo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  The analysis for the regulation of IEC differentiation by the switching mechanism of GSK3Principal Investigator

    • Principal Investigator
      TSUCHIYA Kiichiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒト大腸上皮培養による大腸癌幹細胞の分化破綻機構解析Principal Investigator

    • Principal Investigator
      土屋 輝一郎
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  The elucidation of functional regulation and pathogenesis in the entire human small intestine.

    • Principal Investigator
      ARAKI Akihiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  The regulation of Paneth cells gene expression by Hath1Principal Investigator

    • Principal Investigator
      TSUCHIYA Kiichirou
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  CEACAM1 regulates the cytokine network in intestinal mucosa

    • Principal Investigator
      NAGAISHI Takashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Regeneration of intestinal mucosa and molecular mechanism of the failure of intestinal epithelial cells under intestinal inflammation.

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  The analysis of the regulation in intestinal differentiation by thecomprehensive search of Hath1 target genesPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Kiichirou
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  腸管粘膜局所IL-7ネットワーク制御応用による新規免疾統御療法開発

    • Principal Investigator
      渡辺 守
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification of the crosstalk between Notch signaling and Wnt signaling in the differentiation of the intestinal epithelial cells.

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Clarification of the interaction between the differentiation and immune regulation of goblet cells by Math1.Principal Investigator

    • Principal Investigator
      TSUCHIYA Kiichiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification of the Notch signal in intestinal epithelial cells and the failure of the intestinal differentiation in chronic colitis.

    • Principal Investigator
      OKADA Eriko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  粘膜免疫の特殊性を応用した腸管免疫統御療法の開発

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] Intestinal phenotype is maintained by Atoh1 in the cancer region of intraductal papillary mucinous neoplasm.2021

    • Author(s)
      Katsukura Nobuhiro、Watanabe Sho、Shirasaki Tomoaki、Hibiya Shuji、Kano Yoshihito、Akahoshi Keiichi、Tanabe Minoru、Kirimura Susumu、Akashi Takumi、Kitagawa Masanobu、Okamoto Ryuichi、Watanabe Mamoru、Tsuchiya Kiichiro
    • Journal Title

      Cancer Sci.

      Volume: 112 Pages: 932-944

    • DOI

      10.1111/cas.14755

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K23909, KAKENHI-PROJECT-20K22867, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19K17425
  • [Journal Article] Nickel ions attenuate autophagy flux and induce transglutaminase 2 (TG2) mediated post-translational modification of SQSTM1/p622021

    • Author(s)
      Emi Aonuma, Akiko Tamura, Hiroki Matsuda, Takehito Asakawa, Yuriko Sakamaki, Kana Otsubo, Yoichi Nibe, Michio Onizawa, Yasuhiro Nemoto, Takashi Nagaishi, Kiichiro Tsuchiya, Tetsuya Nakamura, Motohiro Uo, Mamoru Watanabe, Ryuichi Okamoto, Shigeru Oshima.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 542 Pages: 17-23

    • DOI

      10.1016/j.bbrc.2021.01.023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17426
  • [Journal Article] Schlafen 11 is a novel target for mucosal regeneration in Ulcerative Colitis.2021

    • Author(s)
      Watanabe Sho、Nishimura Ryu、Shirasaki Tomoaki、Katsukura Nobuhiro、Hibiya Shuji、Kirimura Susumu、Negi Mariko、Okamoto Ryuichi、Matsumoto Yuka、Nakamura Tetsuya、Watanabe Mamoru、Tsuchiya Kiichiro
    • Journal Title

      J Crohns Colitis.

      Volume: inpress

    • DOI

      10.1093/ecco-jcc/jjab032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K22867, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19K17425
  • [Journal Article] Notch and TNF-a signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients.2021

    • Author(s)
      Kuno Reiko、Ito Go、Kawamoto Ami、Hiraguri Yui、Sugihara Hady Yuki、Takeoka Sayaka、Nagata Sayaka、Takahashi Junichi、Tsuchiya Mao、Anzai Sho、Mizutani Tomohiro、Shimizu Hiromichi、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Watanabe Mamoru、Okamoto Ryuichi
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 25 Pages: 100906-100906

    • DOI

      10.1016/j.bbrep.2020.100906

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-20K22895, KAKENHI-PROJECT-20K22920, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17484, KAKENHI-PROJECT-19K23990
  • [Journal Article] Crohn disease: magnetic resonance enterocolonography features of endoscopic ulcer stages reclassified with the healing process and the relationships to prognoses2021

    • Author(s)
      Yoshio Kitazume, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Yusuke Ogihara, Tomoyuki Fujioka, Junichi Tsuchiya, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi
    • Journal Title

      Jpn J Radiol

      Volume: 39 Issue: 5 Pages: 459-476

    • DOI

      10.1007/s11604-020-01082-5

    • NAID

      210000160272

    • ISSN
      1867-1071, 1867-108X
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378
  • [Journal Article] Funcional analysis of isoflavones using patient-derived human colonic organoids.2021

    • Author(s)
      Tsuchiya Mao、Ito Go、Hama Minami、Nagata Sayaka、Kawamoto Ami、Suzuki Kohei、Shimizu Hiromichi、Anzai Sho、Takahashi Junichi、Kuno Reiko、Takeoka Sayaka、Hiraguri Yui、Sugihara Hady Yuki、Mizutani Tomohiro、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Watanabe Mamoru、Okamoto Ryuichi
    • Journal Title

      BBRC

      Volume: 542 Pages: 40-47

    • DOI

      10.1016/j.bbrc.2021.01.021

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-20K22895, KAKENHI-PROJECT-20K22920, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17484, KAKENHI-PROJECT-19K23990
  • [Journal Article] Intraepithelial Lymphocytes Suppress Intestinal Tumor Growth by Cell-to-Cell Contact via CD103/E-Cadherin Signal2021

    • Author(s)
      Ryo Morikawa, Yasuhiro Nemoto, Yuki Yonemoto, Shohei Tanaka, Yuria Takei, Shigeru Oshima, Takashi Nagaishi, Kiichiro Tsuchiya, Kengo Nozaki , Tomohiro Mizutani, Tetsuya Nakamura, Mamoru Watanabe, Ryuichi Okamoto.
    • Journal Title

      Cellular and Molecular Gastroenterology and Hepatology

      Volume: 11 Pages: 1483-1503

    • DOI

      10.1016/j.jcmgh.2021.01.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02790, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-18K07964
  • [Journal Article] High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage.2020

    • Author(s)
      Tanaka Shohei、Nemoto Yasuhiro、Takei Yuria、Morikawa Ryo、Oshima Shigeru、Nagaishi Takashi、Okamoto Ryuichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Stutte Susanne、Watanabe Mamoru
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 522 Pages: 971-977

    • DOI

      10.1016/j.bbrc.2019.11.158

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K07934
  • [Journal Article] Small bowel healing detected by endoscopy in patients with Crohn's disease after treatment with antibodies against tumor necrosis factor.2020

    • Author(s)
      Takenaka Kento、Fujii Toshimitsu、Suzuki Kohei、Shimizu Hiromichi、Motobayashi Maiko、Hibiya Shuji、Saito Eiko、Nagahori Masakazu、Watanabe Mamoru、Ohtsuka Kazuo
    • Journal Title

      J Gastroenterol.

      Volume: inpress Pages: 1545-1552

    • DOI

      10.1016/j.cgh.2019.08.024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-19K17484, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19K17425
  • [Journal Article] CD8αα+ T cells show amoeboid shape and frequent morphological change in vitro, and localize to small intestinal intraepithelial region in vivo.2020

    • Author(s)
      Takei Yuria、Nemoto Yasuhiro、Morikawa Ryo、Tanaka Shohei、Oshima Shigeru、Nagaishi Takashi、Okamoto Ryuichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Watanabe Mamoru
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 523 Pages: 328-335

    • DOI

      10.1016/j.bbrc.2019.12.021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K07934
  • [Journal Article] High b-value computed diffusion-weighted imaging for differentiating bowel inflammation in Crohn’s disease.2020

    • Author(s)
      Yoshio Kitazume, Junichi Tsuchiya, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Ryosuke Watanabe, Tomoyuki Fujioka, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi
    • Journal Title

      Eur J Raiol.

      Volume: 133 Pages: 109362-109362

    • DOI

      10.1016/j.ejrad.2020.109362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-19H01050
  • [Journal Article] Time course alterations of virus sequences and immunoglobulin titers in a chronic hepatitis E patient2020

    • Author(s)
      Nitta Sayuri、Takahashi Kazuaki、Kawai‐Kitahata Fukiko、Tsuchiya Jun、Sato Ayako、Miyoshi Masato、Murakawa Miyako、Itsui Yasuhiro、Nakagawa Mina、Azuma Seishin、Kakinuma Sei、Watanabe Mamoru、Asahina Yasuhiro
    • Journal Title

      Hepatol Res.

      Volume: 50 Pages: 524-531

    • DOI

      10.1111/hepr.13480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09407, KAKENHI-PROJECT-17K19647, KAKENHI-PROJECT-19K08415, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-20K08303, KAKENHI-PROJECT-18H02790, KAKENHI-PROJECT-19H03635, KAKENHI-PROJECT-18K07964, KAKENHI-PROJECT-19K17453
  • [Journal Article] Receptor‐Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial cells2020

    • Author(s)
      Otsubo K, Maeyashiki C, Nibe Y, Tamura A, Aonuma E, Matsuda H, Kobayashi M, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Torii S, Itakura E, Watanabe M, Oshima S.
    • Journal Title

      FEBS Lett.

      Volume: 594 Pages: 1586-1595

    • DOI

      10.1002/1873-3468.13748

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K22413, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-16H06167, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17426
  • [Journal Article] Vasoactive Intestinal Peptide Derived from Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts2020

    • Author(s)
      Sato A, Koshikawa N, et al.
    • Journal Title

      Hepatology Communications

      Volume: 4 Issue: 2 Pages: 235-254

    • DOI

      10.1002/hep4.1459

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07964, KAKENHI-PROJECT-19K08415, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-19K17392, KAKENHI-PROJECT-19K17453, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-18H02790, KAKENHI-PROJECT-17K09406, KAKENHI-PROJECT-17K09407, KAKENHI-PROJECT-17K19647, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027, KAKENHI-PROJECT-19H03635
  • [Journal Article] Objective evaluation for treat to target in Crohn’s disease2020

    • Author(s)
      Takenaka Kento、Kitazume Yoshio、Fujii Toshimitsu、Tsuchiya Kiichiro、Watanabe Mamoru、Ohtsuka Kazuo
    • Journal Title

      Journal of Gastroenterology

      Volume: 55 Pages: 579-587

    • DOI

      10.1007/s00535-020-01678-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-18K07902
  • [Journal Article] A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors2019

    • Author(s)
      Fukamachi H., Kim S., K., Koh J., Lee H. S., Sasaki Y., Yamashita K., Nishikawaji T., Shimada S., Akiyama Y., Byeon S. J., Bae D. H., Okuno K., Nakagawa M., Tanioka T., Inokuchi M., Kawachi H., Tsuchiya K., Kojima K., Tokino T., Eishi Y., Kim Y. S., Kim W. H., Yuasa Y., Tanaka S.
    • Journal Title

      J Exp Clin Cancer Res

      Volume: 38 Pages: 127-127

    • DOI

      10.1186/s13046-019-1121-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-16H06279
  • [Journal Article] Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids.2019

    • Author(s)
      Nishimura R, Shirasaki T, Tsuchiya K, Miyake Y, Watanabe Y, Hibiya S, Watanabe S, Nakamura T, Watanabe M
    • Journal Title

      J Gastroenterol

      Volume: in press Pages: 608-620

    • DOI

      10.1007/s00535-018-01540-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-17H06654, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K15930, KAKENHI-PROJECT-19K17425
  • [Journal Article] Predictors of mucosal healing during induction therapy in patients with acute moderate-to-severe ulcerative colitis.2019

    • Author(s)
      Motobayashi Maiko、Matsuoka Katsuyoshi、Takenaka Kento、Fujii Toshimitsu、Nagahori Masakazu、Ohtsuka Kazuo、Iwamoto Fumihiko、Tsuchiya Kiichiro、Negi Mariko、Eishi Yoshinobu、Watanabe Mamoru
    • Journal Title

      J. Gastroenterol. Hepatol.

      Volume: in press Pages: 1004-1010

    • DOI

      10.1111/jgh.14565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19K08438
  • [Journal Article] Mutation by CRISPR System Enhances the Malignant Potential of Colon Cancer.2019

    • Author(s)
      Watanabe S, Tsuchiya K, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
    • Journal Title

      Molecular Cancer Research

      Volume: in press Pages: 1459-1467

    • DOI

      10.1158/1541-7786.mcr-18-1195

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-19K17425, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-18K19535
  • [Journal Article] Comprehensive genetic analysis of cholangiolocellular carcinoma with a coexistent hepatocellular carcinoma-like area and metachronous hepatocellular carcinoma.2019

    • Author(s)
      Kawai-Kitahata F, Asahina Y, Kaneko S, Tsuchiya J, Sato A, Miyoshi M, Tsunoda T, Inoue-Shinomiya E, Murakawa M, Nitta S, Itsui Y, Nakagawa M, Azuma S, Kakinuma S, Tanabe M, Sugawara E, Takemoto A, Ojima H, Sakamoto M, Muraoka M, Takano S, Maekawa S, Enomoto N and Watanabe M.
    • Journal Title

      HEPATOLOGY RESEARCH

      Volume: 49 Pages: 1466-1474

    • DOI

      10.1111/hepr.13403

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07964, KAKENHI-PROJECT-19K08415, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-19K17392, KAKENHI-PROJECT-19K17453, KAKENHI-PROJECT-18H02790, KAKENHI-PROJECT-19H03635, KAKENHI-PROJECT-19H03638, KAKENHI-PROJECT-17K09406, KAKENHI-PROJECT-17K09407, KAKENHI-PROJECT-17K19647
  • [Journal Article] Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients.2019

    • Author(s)
      Kawamoto Ami、Nagata Sayaka、Anzai Sho、Takahashi Junichi、Kawai Mao、Hama Minami、Nogawa Daichi、Yamamoto Kouhei、Kuno Reiko、Suzuki Kohei、Shimizu Hiromichi、Hiraguri Yui、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Kitagawa Masanobu、Okamoto Ryuichi、Watanabe Mamoru
    • Journal Title

      J Crohns Colitis

      Volume: 13 Pages: 495-509

    • DOI

      10.1093/ecco-jcc/jjy180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-18K15774, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-18H02791
  • [Journal Article] Novel polyubiquitin imaging system, PolyUb-FC, reveals that K33-linked polyubiquitin is recruited by SQSTM1/p622018

    • Author(s)
      Yoichi Nibe, Shigeru Oshima, Masanori Kobayashi, Chiaki Maeyashiki, Yu Matsuzawa, Kana Otsubo, Hiroki Matsuda, Emi Aonuma, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Shinichiro Nakada, Mamoru Watanabe
    • Journal Title

      Autophagy

      Volume: 22 Pages: 347-358

    • DOI

      10.1080/15548627.2017.1407889

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-16K15423, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-26241014
  • [Journal Article] Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties.2018

    • Author(s)
      Suzuki Kohei、Murano Tatsuro、Shimizu Hiromichi、Ito Go、Nakata Toru、Fujii Satoru、Ishibashi Fumiaki、Kawamoto Ami、Anzai Sho、Kuno Reiko、Kuwabara Konomi、Takahashi Junichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Watanabe Mamoru、Okamoto Ryuichi
    • Journal Title

      J Gastroenterol.

      Volume: 印刷中 Pages: 1035-1047

    • DOI

      10.1007/s00535-018-1437-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-16K09302, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674
  • [Journal Article] Contribution of ATOH1 + Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium2018

    • Author(s)
      Ishibashi Fumiaki、Shimizu Hiromichi、Nakata Toru、Fujii Satoru、Suzuki Kohei、Kawamoto Ami、Anzai Sho、Kuno Reiko、Nagata Sayaka、Ito Go、Murano Tatsuro、Mizutani Tomohiro、Oshima Shigeru、Tsuchiya Kiichiro、Nakamura Tetsuya、Watanabe Mamoru、Okamoto Ryuichi
    • Journal Title

      Stem Cell Rep.

      Volume: 10 Pages: 27-42

    • DOI

      10.1016/j.stemcr.2017.11.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19513
  • [Journal Article] Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine.2017

    • Author(s)
      Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R
    • Journal Title

      Data in Brief

      Volume: 10 Pages: 551-556

    • DOI

      10.1016/j.dib.2016.12.045

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284
  • [Journal Article] Long-term Inflammation Transforms Intestinal Epithelial Cells of Colonic Organoids.2017

    • Author(s)
      Hibiya S, Tsuchiya K, Hayashi R, Horita N, Watanabe S, Shirasaki T, Nishimura R, Kimura N, Nishimura T, Gotoh N, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Journal Title

      Journal of Crohn's and Colitis

      Volume: 61 Pages: 621-630

    • DOI

      10.1093/ecco-jcc/jjw186

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H06770, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-17K15930, KAKENHI-PROJECT-17H06654, KAKENHI-PROJECT-16K09302
  • [Journal Article] Caudal type homeobox 2 expression induced by leukocytapheresis might be associated with mucosal healing in ulcerative colitis.2017

    • Author(s)
      Tsuchiya K, Hayashi R, Fukushima K, Hibiya S, Horita N, Negi M, Itoh E, Akashi T, Eishi Y, Motoya S, Takeuchi Y, Kunisaki R, Fukunaga K, Nakamura S, Yoshimura N, Takazoe M, Iizuka B, Suzuki Y, Nagahori M, Watanabe M
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 61 Pages: 1032-1039

    • DOI

      10.1111/jgh.13645

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-17H06654
  • [Journal Article] Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors.2017

    • Author(s)
      Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 482 Pages: 1296-1303

    • DOI

      10.1016/j.bbrc.2016.12.031

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284
  • [Journal Article] HADHA, the alpha subunit of the mitochondrial trifunctional protein, is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells.2017

    • Author(s)
      Maeyashiki C, Oshima S, Otsubo K, Kobayashi M, Nibe Y, Matsuzawa Y, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 484 Pages: 636-641

    • DOI

      10.1016/j.bbrc.2017.01.159

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-16H06771, KAKENHI-PROJECT-15K15288, KAKENHI-PROJECT-16K15423
  • [Journal Article] Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.2017

    • Author(s)
      Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K
    • Journal Title

      Mucosal Immunology

      Volume: 10 Pages: 446-445

    • DOI

      10.1038/mi.2016.58

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H02511, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-15K15152, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-24113002
  • [Journal Article] Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R.2016

    • Author(s)
      Kojima, T., Tsuchiya, K., Ikemizu, S., Yoshikawa, S., Yamanishi, Y., Watanabe, M., and Karasuyama, H.
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 36457-36457

    • DOI

      10.1038/srep36457

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-15K20969
  • [Journal Article] The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development.2016

    • Author(s)
      Kobayashi M, Oshima S, Maeyashiki C, Nibe Y, Otsubo K, Matsuzawa Y, Memoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 36780-36780

    • DOI

      10.1038/srep36780

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-15K15288
  • [Journal Article] PGE(2) is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells.2016

    • Author(s)
      Fujii S, Okamoto R, Suzuki K, Kawamoto A, Ishibashi F, Nakata T, Murano T, Ito G, Shimizu H, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Araki A, Ohtsuka K, Watanabe M
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 36795-36795

    • DOI

      10.1038/srep36795

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-16K09302
  • [Journal Article] Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease.2016

    • Author(s)
      Hayashi R , Tsuchiya K, Okamoto R,Watanabe M,et al
    • Journal Title

      Inflamm Bowel Dis.

      Volume: 22 Pages: 1119-1128

    • DOI

      10.1097/mib.0000000000000707

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16K09302
  • [Journal Article] TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy.2015

    • Author(s)
      Matsuzawa Y, Oshima S, Takahara M, Maeyashiki C, Nemoto Y, Kobayashi M, Nibe Y, Nozaki K, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Averil Ma, Watanabe M
    • Journal Title

      Autophagy

      Volume: 11 Pages: 1052-1062

    • DOI

      10.1080/15548627.2015.1055439

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15288, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-25460946, KAKENHI-PROJECT-25293170
  • [Journal Article] Associations of HLA class I alleles in Japanese patients with Crohn's disease.2015

    • Author(s)
      102)Oryoji D, Hisamatsu T, Tsuchiya K, Umeno J, Ueda S, Yamamoto K, Matsumoto T, Watanabe M, Hibi T, Sasazuki T.
    • Journal Title

      Genes Immun.

      Volume: 16 Pages: 54-56

    • DOI

      10.1038/gene.2014.61

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22133009, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704
  • [Journal Article] Reduced human α-defensin 6 in non-inflamed jejunal tissue of Crohn’s disease patients2015

    • Author(s)
      Hayashi R , Tsuchiya K, Okamoto R, Watanabe M.et al.
    • Journal Title

      Inflammatory Bowel Diseases

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Journal Article] RIPK3 regulates p62- LC3 complex formation via the caspase-8-dependent cleavage of p622015

    • Author(s)
      Y. Matsuzawa , S. Oshima, Y. Nibe, M.Kobayashi, C. Maeyashiki, Y. Nemoto, T. Nagaishi, R. Okamoto R, K. Tsuchiya, T. Nakamura, M. Watanabe.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 456(1) Pages: 298-304

    • DOI

      10.1016/j.bbrc.2014.11.075

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25460946, KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-26221307
  • [Journal Article] uppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer2015

    • Author(s)
      Oshima H, Nakayama M, Han TS, Naoi K, Ju X, Maeda Y, Robine S, Tsuchiya K, Sato T, Sato H, Taketo MM, Oshima M.
    • Journal Title

      Cancer Research

      Volume: 75 Pages: 766-776

    • DOI

      10.1158/0008-5472.can-14-2036

    • NAID

      120005593962

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25430107, KAKENHI-PROJECT-26430110, KAKENHI-PROJECT-25460382
  • [Journal Article] Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease.2015

    • Author(s)
      Tsuchiya K
    • Journal Title

      Front Gastrointest Res.

      Volume: 34 Pages: 1-8

    • DOI

      10.1159/000381380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-15H04808
  • [Journal Article] Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line.2015

    • Author(s)
      Keita Fukushima, Kiichiro Tsuchiya,Okamoto Ryuichi, Mamoru Watanabe,et al
    • Journal Title

      Cancer Sci.

      Volume: 106 Pages: 1000-1007

    • DOI

      10.1111/cas.12703

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-15K15288, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-25293170
  • [Journal Article] Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells.2014

    • Author(s)
      Murano T, Okamoto R, Ito G, Nakata T, Hibiya S, Shimizu H, Fujii S, Kano Y, Mizutani T, Yui S, Akiyama-Morio J, Nemoto Y, Tsuchiya K, Nakamura T, Watanabe M
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 443 Pages: 840-6

    • DOI

      10.1016/j.bbrc.2013.12.061

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524, KAKENHI-PROJECT-26221307
  • [Journal Article] Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine2014

    • Author(s)
      Shimizu H, Okamoto R, Ito G, Nakata T, Suzuki K, Murano T, Mizutani T, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M.
    • Journal Title

      2014

      Volume: 2

    • DOI

      10.7717/peerj.370

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25860524
  • [Journal Article] The advances of balloon endoscope2014

    • Author(s)
      Araki A, Tsuchiya K, Watanabe M.
    • Journal Title

      Clinical Journal of Gastroenterology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460945
  • [Journal Article] Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt.2014

    • Author(s)
      N. Horita, K. Tsuchiya, R. Hayashi, K. Fukushima, S. Hibiya, M. Fukuda, Y. Kano, T. Mizutani, Y. Nemoto, S. Yui, R. Okamoto, T. Nakamura, M. Watanabe
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 454 Pages: 493-499

    • DOI

      10.1016/j.bbrc.2014.10.091

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524, KAKENHI-PROJECT-26221307
  • [Journal Article] Bonemarrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4+ memory T cells.2013

    • Author(s)
      Nemoto Y, Nakamura T, Watanabe M et al
    • Journal Title

      Gut

      Volume: 62 Pages: 1142-1152

    • DOI

      10.1136/gutjnl-2012-302029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
  • [Journal Article] 消化管幹細胞と消化器がん幹細胞2013

    • Author(s)
      土屋輝一郎
    • Journal Title

      日本内科学会雑誌

      Volume: 102 Pages: 2273-2278

    • NAID

      10031202663

    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Journal Article] Lineage-specific expression of Bestrophin-2 and Bestrophin-4 in human intestinal epithelial cells2013

    • Author(s)
      Ito G, Okamoto R, Nakamura T, Watanabe M et al
    • Journal Title

      PLoS One.

      Volume: 8

    • DOI

      10.1371/journal.pone.0079693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229005, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524
  • [Journal Article] 【特集:機能性消化管障害(FGID):診断と治療の進歩】I. FGIDの基本的知識 4. 感染症や腸内細菌の意義(免疫学的異常について)2013

    • Author(s)
      土屋輝一郎
    • Journal Title

      日本内科学会雑誌

      Volume: 102 Pages: 25-31

    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Journal Article] Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota.2013

    • Author(s)
      Nemoto Y, Watanabe M et al
    • Journal Title

      J Immunol

      Volume: 190 Pages: 6616-25

    • DOI

      10.4049/jimmunol.1202930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24659375, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367
  • [Journal Article] 【特集:機能性消化管障害(FGID):診断と治療の進歩】I. FGIDの基本的知識 4. 感染症や腸内細菌の意義(免疫学的異常について).2013

    • Author(s)
      土屋輝一郎
    • Journal Title

      日本内科学会雑誌

      Volume: 102 Pages: 25-31

    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Journal Article] IL-7 promotes long-term in vitro survival of unique long-lived memory subset generated from mucosal effector memory CD4+ T cells in chronic colitis mice2013

    • Author(s)
      Takahara M, Nemoto Y, Oshima S, Matsuzawa Y, Kanai T, Okamoto R, Tsuchiya K, Nakamura T, Yamamoto K, Watanabe M.
    • Journal Title

      Immunol Lett

      Volume: 156 Pages: 82-93

    • DOI

      10.1016/j.imlet.2013.09.001

    • NAID

      120005468269

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170
  • [Journal Article] 消化管幹細胞と消化器がん幹細胞2013

    • Author(s)
      土屋輝一郎
    • Journal Title

      日本内科学会雑誌

      Volume: 102 Pages: 2273-2278

    • NAID

      10031202663

    • Data Source
      KAKENHI-PROJECT-24590935
  • [Journal Article] The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein2013

    • Author(s)
      Kano Y
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 432 Pages: 175-181

    • DOI

      10.1016/j.bbrc.2013.01.034

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23390062, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790357, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590935, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
  • [Journal Article] 消化管幹細胞と消化器がん幹細胞2013

    • Author(s)
      土屋輝一郎
    • Journal Title

      日本内科学会雑誌

      Volume: 102 Pages: 2273-2278

    • NAID

      10031202663

    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Journal Article] 【特集:機能性消化管障害(FGID):診断と治療の進歩】I. FGIDの基本的知識 4. 感染症や腸内細菌の意義(免疫学的異常について)2013

    • Author(s)
      土屋輝一郎
    • Journal Title

      日本内科学会雑誌

      Volume: 102 Pages: 25-31

    • Data Source
      KAKENHI-PROJECT-24590935
  • [Journal Article] Endoscopic ultrasound with double-balloon endoscopy for the diagnosis of inverted Meckel's diverticulum: a case report.2012

    • Author(s)
      Araki A, Tsuchiya K, Oshima S, Okada E,Suzuki S, Akiyama JM, Fujii T, OkamotoR, Watanabe M
    • Journal Title

      J Med Case Rep.

      Volume: 6(1) Pages: 328-328

    • DOI

      10.1186/1752-1947-6-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23790776, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590935, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
  • [Journal Article] Suppression of hath1 gene expression directly regulated by hes1 via notch signaling is associated with goblet cell depletion in ulcerative colitis2012

    • Author(s)
      Zheng X, Nakamura T, et al
    • Journal Title

      Inflamm Bowel Di

      Volume: 17 Pages: 2251-2260

    • DOI

      10.1002/ibd.21611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24659359
  • [Journal Article] Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro.2012

    • Author(s)
      Mizutani T, Nakamura T, et al
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 419 Pages: 238-243

    • DOI

      10.1016/j.bbrc.2012.01.155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590803, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PUBLICLY-24112508
  • [Journal Article] Modified single-operator method for double-balloon endoscopy.2012

    • Author(s)
      Araki A, Suzuki S, Tsuchiya K, OshimaS, Okada E, Watanabe M
    • Journal Title

      Dig Endosc.

      Volume: 24(6) Pages: 470-4

    • DOI

      10.1111/j.1443-1661.2012.01321.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-23130506
  • [Journal Article] Luminal CD4+ T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation.2012

    • Author(s)
      Nemoto Y, Watanabe M
    • Journal Title

      Gastroenterology.

      Volume: 141 Pages: 2030-2039

    • DOI

      10.1053/j.gastro.2011.08.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590804, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777
  • [Journal Article] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell2012

    • Author(s)
      Yui S, Nakamura T, Sato T, Nemoto Y, Mizutani T, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Clevers H, and Watanabe M
    • Journal Title

      Nat. Med.

      Volume: 18 Pages: 618-23

    • DOI

      10.1038/nm.2695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590803, KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-21590806, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-23890204, KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-24790684, KAKENHI-PUBLICLY-24112508, KAKENHI-PUBLICLY-24112523
  • [Journal Article] The development of colitogenic CD4+ Tcells is regulated by IL-7 in coll aboration with natural killer cell function in a murine model of colitis2012

    • Author(s)
      Yamaji O, Totsuka T
    • Journal Title

      J. Immunol

      Volume: 188 Pages: 2524-2536

    • DOI

      10.4049/jimmunol.1100371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590804, KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-21590806, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23390112, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659223, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PLANNED-23102003
  • [Journal Article] The suppression of Hath1 gene expression directly regulated by Hes1 via Notch signaling is associated with goblet cell depletion in ulcerative colitis.2011

    • Author(s)
      Zheng X, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Inflamm Bowel Dis.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011

    • Author(s)
      Funaoka Y, Sakamoto N, Suda G, Itsui Y, Nakagawa M, Kakinuma S, Watanabe T, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K,Watanabe M
    • Journal Title

      J Virol

      Volume: 85 Pages: 5986-5994

    • DOI

      10.1128/jvi.02583-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22790633, KAKENHI-PUBLICLY-23130506
  • [Journal Article] Inhibitory effect of a triterpenoid compound, with or without interferon-alpha, on hepatitis C virus infection2011

    • Author(s)
      Watanabe T, Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
    • Journal Title

      Antimicrobial Agents and Chemotherapy

      Volume: 55(6) Pages: 2537-2545

    • DOI

      10.1128/aac.01780-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790778
  • [Journal Article] Magnetic resonance enterocolonography is useful for simultaneous evaluation of small and lage intestinal lesions in Crohn's disease2011

    • Author(s)
      Hyun SB, Kitazume Y, Suzuki S, Watanabe M, et al
    • Journal Title

      Inflamm Bowel Dis.

      Volume: 17 Pages: 1063-1072

    • DOI

      10.1002/ibd.21510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-21590806, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23590934
  • [Journal Article] Upregulated IL-7Rα expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis2011

    • Author(s)
      Shinohara, T., et al
    • Journal Title

      J Immunol

      Volume: 186 Pages: 2623-2632

    • DOI

      10.4049/jimmunol.1000057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590531, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506
  • [Journal Article] The suppression of Hath1 gene expression directly regulated by Hes1 via Notch signaling is associated with goblet cell depletion in ulcerative colitis.2011

    • Author(s)
      Zheng X, Tsuchiya K, Okamoto R, Iwasaki M, Kano Y, Sakamoto N, Nakamura T, Watanabe M
    • Journal Title

      Inflamm Bowel Dis. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and K1f42011

    • Author(s)
      Iwasaki M, Tsuchiya K, Suzuki S, Watanabe M, et al
    • Journal Title

      J Gastroenterol.

      Volume: 46 Pages: 191-202

    • DOI

      10.1007/s00535-010-0346-x

    • NAID

      10029027237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790777
  • [Journal Article] Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hathl and KIN.2011

    • Author(s)
      Iwasaki M, Tsuchiya K, Araki A, Watanabe M, et al.
    • Journal Title

      J Gastroenterol.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590694
  • [Journal Article] Upregulated IL-7 Receptor {alpha} Expression on Colitogenic Memory CD4+ T Cells May Participate in the Development and Persistence of Chronic Colitis.2011

    • Author(s)
      Shinohara T, Nemoto Y, Kanai T, Kameyama K, Okamoto R, Tsuchiya K, Nakamura T, Totsuka T, Ikuta K, Watanabe M
    • Journal Title

      J Immunol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf4.2010

    • Author(s)
      Iwasaki M, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      J Gastroenterol.

      Volume: (in press)

    • NAID

      10029027237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells in chronic colitis.2010

    • Author(s)
      Kameyama K, Tsuchiya K, Watanabe M(他8名、6番目)
    • Journal Title

      Eur J Immunol 40(9)

      Pages: 2423-2436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Magnetic resonance enterocolonography is useful for simultaneous evaluation of small and large intestinal lesions in Crohn's disease.2010

    • Author(s)
      Hyun SB, Kitazume Y, Nagahori M, Toriihara A, Fujii T, Tsuchiya K, Suzuki S, Okada E, Araki A, Naganuma M, Watanabe M.
    • Journal Title

      Inflamm Bowel Dis. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2010

    • Author(s)
      Nishimura-Sakurai Y, Tsuchiya K, Watanabe M(他18名、18番目)
    • Journal Title

      J Gastroenterol. 45

      Pages: 523-536

    • NAID

      10027216127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.2010

    • Author(s)
      Akiyama J, Tsuchiya K, Watanabe M(他5名、6番目)
    • Journal Title

      Biochemical and Biophysical Research Communications. 393

      Pages: 662-667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf4.2010

    • Author(s)
      Iwasaki M, Tsuchiya K, Okamoto R, Zheng X, Kano Y, Okamoto E, Okada E, Araki A, Suzuki S, Sakamoto N, Kitagaki K, Akashi T, Eishi Y, Nakamura T, Watanabe M
    • Journal Title

      J Gastroenterol in press

    • NAID

      10029027237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Inhibition of HCV replication by a specific inhibitor of serin-arginine-rich protein kinase.2010

    • Author(s)
      Karakama Y, Tsuchiya K, Watanabe M(他10名、10番目)
    • Journal Title

      Antimicrob Agent Chemother. 54(8)

      Pages: 3179-3186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.2010

    • Author(s)
      Akiyama J, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications.

      Volume: 393 Pages: 662-667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells2010

    • Author(s)
      Akiyama J, Tsuchiya K, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.2010

    • Author(s)
      Suda G, Tsuchiya K, Watanabe M(他15名、14番目)
    • Journal Title

      Virology. 407(1)

      Pages: 80-90

    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Magnetic resonance enterocolonography is u seful for simultaneous evaluation of small and large intestinal lesions in Crohn's disease.2010

    • Author(s)
      Hyun SB, Tsuchiya K, Okada E, Araki A, Watanabe M.
    • Journal Title

      Inflamm Bowel Dis.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590694
  • [Journal Article] Cell culture and in-vivo analyses of plaque-derived cytopathic hepatitis C virus mutants.2010

    • Author(s)
      Mishima K, Tsuchiya K, Watanabe M(他12名、10番目)
    • Journal Title

      Virology. 405(2)

      Pages: 361-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T Cells in chronic colitis2009

    • Author(s)
      Totsuka T, Kanai T, Nemoto Y, Tomita T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Akiba H, Okumura K, Yagita H, Watanabe M
    • Journal Title

      J Immunol. 182

      Pages: 6079-6087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Requirement of Notch activation duringregeneration of the intestinal epithelia2009

    • Author(s)
      Okamoto R, Tsuchiya K, Nemoto Y, AkiyamaJ, Nakamura T, Kanai T, Watanabe M
    • Journal Title

      Am JPhysiol GI & Liver 296

      Pages: 23-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Single-operator double-balloon endoscopy2009

    • Author(s)
      Arake A, Tsuchiya K, etal
    • Journal Title

      J Gastroenterol Hepatol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Musashi-1 suppresses expression of Paneth cell specific genes in human intestinal epithelial cells.2009

    • Author(s)
      Murayama M, Tsuchiya K, Watanabe M(他6名、3番目)
    • Journal Title

      J Gastroenterol. 44

      Pages: 173-182

    • NAID

      10025173646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia2009

    • Author(s)
      Okamoto R, Tsuchiya K, et al.
    • Journal Title

      Am J Physiol GI & Liver 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4+ memory T cells in chronic colitis2009

    • Author(s)
      Tomita T, Tsuchiya K, et al.
    • Journal Title

      Eur J Immunol. 39

      Pages: 2737-2747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T Cells in chronic colitis2009

    • Author(s)
      Totsuka T, Tsuchiya K, et al.
    • Journal Title

      J Immunol. 182

      Pages: 6079-3087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Signaling pathway via TNF α/NFκB in intestinal epithelial cells may bedirectly involved in colitis- associated carcinogenesis.2009

    • Author(s)
      Onizawa M, Tsuchiya K, Watanabe M(他13名、12番目)
    • Journal Title

      Am J Physiol GI & Liver. 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] RANK-RANKL Signaling Pathway Is Critically Involved in the Function of CD4+CD25+ Regulatory T Cells in Chronic Colitis.2009

    • Author(s)
      Totsuka T, Tsuchiya K, Watanabe M(他9名、6番目)
    • Journal Title

      J Immunol. 182

      Pages: 6079-6087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Requirement of Notch activation during regeneration of theintestinal epithelia.2009

    • Author(s)
      Okamoto R. Tsuchiya K, et al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 296

      Pages: 23-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Single-operator double-balloon endoscopy (DBE) is as effective as dual-operator DBE.2009

    • Author(s)
      Araki A, Tsuchiya K, Watanabe M.(他6名、2番目)
    • Journal Title

      J Gastroenterol Hepatol. 24(5)

      Pages: 770-775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Long-Lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis.2009

    • Author(s)
      Nemoto Y, Tsuchiya K, Watanabe M(他9名、8番目)
    • Journal Title

      J Immunol 183

      Pages: 5059-5068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Long-Lived colitogenic CD4+ Memory T Cells residing outside the intestine participate in the perpetuation of chronic colitis2009

    • Author(s)
      Nemoto Y, Tsuchiya K, et al.
    • Journal Title

      J Immunol. 183

      Pages: 5059-5068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Signaling pathway via TNFα/NFκB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009

    • Author(s)
      Onizawa M, Tsuchiya K, et al.
    • Journal Title

      Am J Physiol GI & Liver 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Signaling pathway via TNF α /NF κ B in intestinal epithelial cellsmay be directly involved in colitis-associated carcinogenesis.2009

    • Author(s)
      Onizawam, Tsuchiya K, etal
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia.2009

    • Author(s)
      Okamoto R, Tsuchiya K, Watanabe M(他4名、2番目)
    • Journal Title

      Am J Physiol GI & Liver. 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Musashi-1 suppresses expression of Paneth cell-specificgenes in human intestinal epithelial cells.2009

    • Author(s)
      Murayama M. Tsuchiya K, etal.
    • Journal Title

      J Gastroenterol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia2009

    • Author(s)
      Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M
    • Journal Title

      Am J Physiol GI & Liver 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Musashi-1 suppresses expression of Paneth cell specific genes in human intestinal epithelial cells2009

    • Author(s)
      Murayama M, Tsuchiya K, et al.
    • Journal Title

      J Gastroenterol. 44

      Pages: 173-182

    • NAID

      10025173646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Journal Article] Long-Lived colitogenic CD4+ Memory T Cells residing outside the intestine participate in the perpetuation of chronic colitis2009

    • Author(s)
      Nemoto Y, Kanai T, Kameyama K, Shinohara T, Sakamoto N, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sudo T, Matsumoto S, Watanabe M
    • Journal Title

      J Immunol. 183

      Pages: 5059-5068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Inducible expression of microRNA-194 is regulated byHNF-1a during intestinal epithelial cell differentiation.2008

    • Author(s)
      Hino K, Tsuchiya K., et al.
    • Journal Title

      RNA 14

      Pages: 1433-1442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion and survival of colitogenic CD4+ T cells in chronic colitis2008

    • Author(s)
      Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, SakamotoN, Akira S, Watanabe M
    • Journal Title

      J Immunol 180

      Pages: 5291-5299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice bymodulating the trafficking of colitogenic CD4十T cells in bone marrow.2008

    • Author(s)
      Fujii T. Tsuchiya K, et al.
    • Journal Title

      Eur J Immunol. 38

      Pages: 3290-3303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state ofcolon cancer2008

    • Author(s)
      Aragaki M, Tsuchiya K, Okamoto R, Yoshioka S, Nakamura T, Sakamoto N, KanaiT, Watanabe M
    • Journal Title

      Biochem Biophys Res Commun 368

      Pages: 923-929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence ofchronic colitis2008

    • Author(s)
      Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M
    • Journal Title

      J Immunol 180

      Pages: 383-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Flagellin stimulation suppresses IL-7 secretion of intestinalepithelial cells.2008

    • Author(s)
      Yoshioka A, Tsuchiya K, et al.
    • Journal Title

      Cytokine 44

      Pages: 57-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis.2008

    • Author(s)
      Tomita T, Tsuchiya K, et. al.
    • Journal Title

      J Immunol. 180

      Pages: 383-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] MyD88-dependent pathway in T Cells directly modulates the expansion of colitogenic CD4+ T Cells in chronic colitisl.2008

    • Author(s)
      Tomita T, Tsuchiya K, et. al.
    • Journal Title

      J Immunol. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Negative Feedback Regulation of Colitogenic CD4 T Cellsby Increased Granulopoiesis.2008

    • Author(s)
      Nemoto YごTsuchiya K., et al.
    • Journal Title

      Inflamm Bowel Dis 14

      Pages: 1491-1503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Colitogenic CD4 Effector-memory T Cells ActivelyRecirculate in Chronic Colitic Mice.2008

    • Author(s)
      Tomita T, Tsuchiya K, et al.
    • Journal Title

      Inflamm Bowel Dis 14

      Pages: 1630-1640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Inducible expression of microRNA-194 is regulated by HNF-1 during intestinal epithelial cell differentiation2008

    • Author(s)
      Hino K, Tsuchiya K, Taro Fukao, KotaroKiga, Ryuichi Okamoto, Tkanori Kanai, Watanabe M
    • Journal Title

      RNA 14

      Pages: 1433-1442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Proteasomal degradation of Atohl by aberrant Wnt signaling maintains the undifferentiated state of colon cancer.2008

    • Author(s)
      Aragaki M, Tsuchiya K, et. al.
    • Journal Title

      Biochem Biophys Res Commun. 368

      Pages: 923-929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion and survival of colitogenic CD4+ T cells in chronic colitis2008

    • Author(s)
      Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M
    • Journal Title

      J Immunol. 180

      Pages: 5291-5299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis2008

    • Author(s)
      Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M
    • Journal Title

      J Immunol. 180

      Pages: 383-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Immunosenescent colitogenic CD4+ T cells convert to regulatory cells and suppress colitis.2008

    • Author(s)
      Totsuka T, Tsuchiya K, et. al.
    • Journal Title

      Eur J Immunol. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis2008

    • Author(s)
      Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M
    • Journal Title

      Inflamm Bowel Dis 14

      Pages: 1491-1503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Colitogenic CD4^+ effector-memory T cells actively recirculate in chronic coliticmice2008

    • Author(s)
      Tomita T, Kanai T, Nemoto Y, Fujii T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Totsuka T, Watanabe M
    • Journal Title

      Inflamm Bowel Dis 14

      Pages: 1630-1640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, et al.
    • Journal Title

      Gastroenterology 132

      Pages: 208-220

    • NAID

      40015644487

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Intestinal Lamina Propria retaining (CD4+CD25+) Regulatory T Cells Is A Suppressive Site of Internal Inflammation.2007

    • Author(s)
      Makita S, Tsuchiya K, et al.
    • Journal Title

      J Immunol. 178

      Pages: 4937-4046

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Intestinal Lamina Propria Retaining CD4+CD25+ Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation.2007

    • Author(s)
      Makita S, Tsuchiya K, et al.
    • Journal Title

      J Immunol. 178

      Pages: 4937-4946

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Intestinal lamina propria retaining CD4+CD25+regulatory T cells is a suppressive site of intestinal inflammation.2007

    • Author(s)
      Makita S, Tsuchiya K, et. al.
    • Journal Title

      J Immunol. 178

      Pages: 4937-4946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Intestinal lamina propria retaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation2007

    • Author(s)
      Makita S, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Yamamoto M, Kiyono H, Watanabe M
    • Journal Title

      J Immunol. 178

      Pages: 4937-4946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Reciprocal targeting of Hathl and β-catenin by Wnt-glycogen synthase kinase 3 β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, Watanabe M, et. al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, Watanabe M, et. al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • NAID

      40015644487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3 β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • NAID

      40015644487

    • Data Source
      KAKENHI-PROJECT-17047015
  • [Journal Article] Intestinal lamina propria retaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation2007

    • Author(s)
      Makita S, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Yamamoto M, Kiyono H, Watanabe M
    • Journal Title

      J Immunol 178

      Pages: 4937-4946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] IL-7 is essential for the development and the persistence of chronic colitis2007

    • Author(s)
      Totsuka T, Kanai T, Nemoto Y, Makita S, Okamoto R, Tsuchiya K, Watanabe M
    • Journal Title

      J Immunol 178

      Pages: 4737-4748

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Intestinal Lamina Propria Retaining CD4+CD25+Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation.2007

    • Author(s)
      Makita S, Tsuchiya K, et al.
    • Journal Title

      J Immunol. (in press)

    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3βin human colon cancer.2007

    • Author(s)
      Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209027
  • [Journal Article] IL-7 is essential for the development and the persistence of chronic colitis2007

    • Author(s)
      Totsuka T, Kanai T, Nemoto Y, Makita S, Okamoto R, Tsuchiya K, Watanabe M
    • Journal Title

      J Immunol. 178

      Pages: 4737-4748

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Journal Article] IL-7 is essential for the development and the persistence of chronic colitis.2007

    • Author(s)
      Totsuka T, Tsuchiya K, et. al.
    • Journal Title

      J Immunol. 178

      Pages: 4737-4748

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3 β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, et al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • NAID

      40015644487

    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Intestinal lamina propria retaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation.2007

    • Author(s)
      Makita S, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      J Immunol. 178

      Pages: 4937-4946

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3 β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • NAID

      40015644487

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209027
  • [Journal Article] Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis.2007

    • Author(s)
      Ito Y, Tsuchiya K, et. al.
    • Journal Title

      Am J Physiol GI & Liver. 394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • NAID

      40015644487

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] IL-7 is essential for the development and the persistence of chronic colitis.2007

    • Author(s)
      Totsuka T, Tsuchiya K, et al.
    • Journal Title

      J Immunol. 178

      Pages: 4737-4748

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] IL-7 is essential for the development and the persistence of chronic colitis.2007

    • Author(s)
      Totsuka T, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      J Immunol. 178

      Pages: 4737-4748

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3β in human colon cancer2007

    • Author(s)
      Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M
    • Journal Title

      Gastroenterology 132

      Pages: 208-220

    • NAID

      40015644487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] IL-7 is essential for the development and the persistence of chronic colitis running title : IL-7-dependent colitis.2007

    • Author(s)
      Totsuka T, Tsuchiya K, et al.
    • Journal Title

      J Immunol. (in press)

    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Reciprocal targeting of Hath1 and β -catenin by Wnt-glycogen synthase kinase 3 β in human colon cancer.2007

    • Author(s)
      Tsuchiya K, et al.
    • Journal Title

      Gastroenterology. 132

      Pages: 208-220

    • NAID

      40015644487

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision.2007

    • Author(s)
      Nakamura T, Tsuchiya K, et. al.
    • Journal Title

      J Gastroenterol. 42

      Pages: 705-710

    • NAID

      10019816553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Journal Article] FTY720 suppresses CD4^+CD44^<high>CD62L^- effector memory T cell-mediated colitis.2006

    • Author(s)
      Fujii R, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Am J Physiol. 291

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] FTY720 suppresses CD4^+CD44^<high>CD62L^- effector memory T cell-mediated colitis2006

    • Author(s)
      Fujii R, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Am J Physiol. 291

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] FTY720 suppresses CD4^+CD44^<high>CD62L effector memory T cell-mediated colitis.2006

    • Author(s)
      Fujii R, Tsuchiya K, et al.
    • Journal Title

      Am J Physiol. 291

    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] FTY720 suppresses CD4^+CD44^<high>CD62L^- effector memory T cell-mediated colitis.2006

    • Author(s)
      Fujii R, Tsuchiya K, et al.
    • Journal Title

      Am J Physiol. 291

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome.2005

    • Author(s)
      Namiki S, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      FEBS Lett. 579

      Pages: 2781-2787

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelia cells during regeneration in the human intestine.2005

    • Author(s)
      Matsumoto T, Tsuchiya K, et al.
    • Journal Title

      Gastroenterology 128

      Pages: 1851-1867

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005

    • Author(s)
      Matsumoto T, Tsuchiya K, et al.
    • Journal Title

      Gastroenterology. 128

      Pages: 1851-1867

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7R^<high> CD4^+ mucosal T cells in mice.2005

    • Author(s)
      Okada E, Tsuchiya K, et al.
    • Journal Title

      Am J Physiol. 291

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome.2005

    • Author(s)
      Namiki S, Tsuchiya K, et al.
    • Journal Title

      FEBS Lett. 579

      Pages: 2781-2787

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590621
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005

    • Author(s)
      Matsumoto T, Tsuchiya K, Watanabe M, et al.
    • Journal Title

      Gastroenterology. 128

      Pages: 1851-1867

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.

    • Author(s)
      Matsumoto T, Tsuchiya K, Watanabe M, et al.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590624
  • [Patent] ダブルバルーン内視鏡用係止具及び内視鏡用アダプタ2013

    • Inventor(s)
      荒木昭博、土屋輝一郎、大島茂
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Acquisition Date
      2013-10-12
    • Data Source
      KAKENHI-PROJECT-22590694
  • [Presentation] IBD病態から繙く再生医療研究への展開と臨床応用2020

    • Author(s)
      土屋輝一郎
    • Organizer
      第3回旭川CDワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] 当院におけるEST後出血への対応2020

    • Author(s)
      小林正典,大塚和朗,土屋輝一郎
    • Organizer
      第99回日本消化器内視鏡学会総会
    • Data Source
      KAKENHI-PROJECT-19K08461
  • [Presentation] IBD病態から繙く再生医療研究への展開と臨床応用2020

    • Author(s)
      土屋輝一郎
    • Organizer
      第3回旭川CDワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] ヒト潰瘍性大腸炎モデルを用いた粘膜治癒に対する新規治療標的の同定2020

    • Author(s)
      渡辺 翔、土屋輝一郎、渡辺 守
    • Organizer
      JDDW2020
    • Data Source
      KAKENHI-PROJECT-19H01050
  • [Presentation] ヒト小腸オルガノイドを用いたクローン病病態解明の試み2020

    • Author(s)
      日比谷秀爾、白崎友彬、勝倉暢洋、渡辺 翔、岡本隆一、土屋輝一郎、渡辺 守
    • Organizer
      第106回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-19H01050
  • [Presentation] Synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients leads to up-regulation of UBD, a ubiquitin-like protein.2019

    • Author(s)
      Kawamoto A, Nagata S, Anzai S, Takahashi J, Kawai M, Hama M, Nogawa D, Yamamoto K, Kuno R, Suzuki K, Shimizu H, Hiraguri Y, Yui S, Oshima S, Tsuchiya K, Nakamura T, Ohtsuka K, Kitagawa M, Okamoto R, Watanabe M
    • Organizer
      ECCO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 炎症性腸疾患モデル構築から癌化モデルへの試み2019

    • Author(s)
      土屋輝一郎
    • Organizer
      第3回 がん三次元培養研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] Synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients leads to up-regulation of UBD, a ubiquitin-like protein.2019

    • Author(s)
      Kawamoto A, Nagata S, Anzai S, Takahashi J, Kawai M, Hama M, Nogawa D, Yamamoto K, Kuno R, Suzuki K, Shimizu H, Hiraguri Y, Yui S, Oshima S, Tsuchiya K, Nakamura T, Ohtsuka K, Kitagawa M, Okamoto R, Watanabe M
    • Organizer
      ECCO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] Long-term inflammation model using human colonic organoids2019

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Tomoaki Shirasaki, Sho Watanabe, Nobuhiro Katsukura, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe
    • Organizer
      The 7th annual meeting of AOCC
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] TP53 mutation in human colonic organoids acquires resistance to in vitro long-term inflammation.2019

    • Author(s)
      Tsuchiya K, Watanabe S, Shirasaki T, Nishimura R, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      ECCO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] Establishment of chronic inflammation model using human small intestinal and colonic organoids2019

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Sho Watanabe, Nobuhiro Katsukura, Tomoaki Shirasaki, Ryuichi Okamoto, Mamoru Watanabe
    • Organizer
      UEG Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] 小腸からIBDそして再生へ2019

    • Author(s)
      土屋輝一郎
    • Organizer
      Advanced GI & Liver Forum 15th
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] ヒトiPS細胞による疾患モデルを利用した先天性肝線維症分子標的の探索2019

    • Author(s)
      柿沼 晴、角田知之、三好正人、紙谷聡英、佐藤綾子、土屋 淳、北畑富貴子、村川美也子、新田沙由梨、井津井康浩、中川美奈、東 正新、朝比奈靖浩、渡辺 守
    • Organizer
      JDDW2019
    • Data Source
      KAKENHI-PROJECT-19K08461
  • [Presentation] Establishment of chronic inflammation model using human small intestinal and colonic organoids.2019

    • Author(s)
      Hibiya S, Tsuchiya K, Nishimura R, Watanabe S, Katsukura N, Shirasaki R, Okamoto R, Watanabe M
    • Organizer
      UEG Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01050
  • [Presentation] Long-term inflammation model using human colonic organoids2019

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Tomoaki Shirasaki, Sho Watanabe, Nobuhiro Katsukura, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe
    • Organizer
      The 7th annual meeting of AOCC
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] Establishment of chronic inflammation model using human small intestinal and colonic organoids2019

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Sho Watanabe, Nobuhiro Katsukura, Tomoaki Shirasaki, Ryuichi Okamoto, Mamoru Watanabe
    • Organizer
      UEG Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] TP53 mutation in human colonic organoids acquires resistance to in vitro long-term inflammation.2019

    • Author(s)
      Tsuchiya K, Watanabe S, Shirasaki T, Nishimura R, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      ECCO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 炎症性腸疾患モデル構築から癌化モデルへの試み2019

    • Author(s)
      土屋輝一郎
    • Organizer
      第3回 がん三次元培養研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] Organoid model for the carcinogenesis process of CAC2019

    • Author(s)
      Kiichiro Tsuchiya
    • Organizer
      IMKASID 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] UC-related and segment-specific properties of patientderived colonic organoids.2019

    • Author(s)
      Suzuki K, Shimizu H, Kawai M, Takahashi J, Anzai S, Kawamoto A, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
    • Organizer
      ECCO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Vasoactive intestinal peptide による胆管形成調節の分子機序2019

    • Author(s)
      佐藤綾子、柿沼 晴、土屋 淳、三好正人、角田知之、井津井康浩、中川美奈、東 正新、朝比奈靖浩、渡辺 守.
    • Organizer
      第26回肝細胞研究会
    • Data Source
      KAKENHI-PROJECT-19K08461
  • [Presentation] 小腸からIBDそして再生へ2019

    • Author(s)
      土屋輝一郎
    • Organizer
      Advanced GI & Liver Forum 15th
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] Organoid model for the carcinogenesis process of CAC2019

    • Author(s)
      Kiichiro Tsuchiya
    • Organizer
      IMKASID 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] TP53 mutation in human colonic organoids acquires resistance to in vitro long-term inflammation.2019

    • Author(s)
      Tsuchiya K, Watanabe S, Shirasaki T, Nishimura R, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      ECCO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] Long-term inflammation model using human colonic organoids.2019

    • Author(s)
      Hibiya S, Tsuchiya K, Nishimura R, Shirasaki T, Watanabe S, Katsukura N, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      AOCC 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01050
  • [Presentation] Fetalization of colonic epithelium medicated by YAP/TAZ links ECM remodeling to tissue regeneration.2018

    • Author(s)
      Yui S, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
    • Organizer
      GI Research Academy2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Tp53 mutation enhances cell proliferation and stemness in human colon epithelial organoids and promotes a resistance against long-term inflammation.2018

    • Author(s)
      Watanabe S, Tsuchiya K, Shirasaki T, Hibiya S, Nishimura S, Katsukura N, Oshima S, Okamoto R, Tetsuya N, Watanabe M
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] Identification of lesion-specific epithelial function of ulcerative colitis by comparing colonic organoids from lesion and non-lesion parts of same patients.2018

    • Author(s)
      Shirasaki T, Tsuchiya K, Nishimura R, Watanabe S, Hibiya S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] Identification of lesion-specific epithelial function of ulcerative colitis by comparing colonic organoids from lesion and non-lesion parts of same patients.2018

    • Author(s)
      Shirasaki T, Tsuchiya K, Nishimura R, Watanabe S, Hibiya S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Lesion-specific gene expression in the Epithelial cells of Crohn’s disease by comparing Small intestinal organoids from active and inactive Lesion in the same patient.2018

    • Author(s)
      Hibiya S, Tsuchiya K, Nishimura R, Shirasaki T, Watanabe S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] Lesion-specific gene expression in the Epithelial cells of Crohn’s disease by comparing Small intestinal organoids from active and inactive Lesion in the same patient.2018

    • Author(s)
      Hibiya S, Tsuchiya K, Nishimura R, Shirasaki T, Watanabe S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Identification of lesion-specific epithelial function of ulcerative colitis by comparing colonic organoids from lesion and non-lesion parts of same patients.2018

    • Author(s)
      Shirasaki T, Tsuchiya K, Nishimura R, Watanabe S, Hibiya S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] The identification of lesion-specific gene expression in intestinal epithelial cells of Ulcerative Colitis by comparing colonic organoids from lesion and non-lesion parts of same patients.2018

    • Author(s)
      Nishimura R, Tsuchiya K, Shirasaki T, Watanabe S, Hibiya S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      The 13th Congress of ECCO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Tp53 mutation enhances cell proliferation and stemness in human colon epithelial organoids and promotes a resistance against long-term inflammation.2018

    • Author(s)
      Watanabe S, Tsuchiya K, Shirasaki T, Hibiya S, Nishimura S, Katsukura N, Oshima S, Okamoto R, Tetsuya N, Watanabe M
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Crohn’s disease patient-derived small intestinal organoids reveal disease-status related modification of stem cell properties. 52018

    • Author(s)
      Suzuki K, Murano T, Hiraguri Y, Takahashi J, Shimizu H,Anzai S, Kuwabara K, Kawamoto A, Ishibashi F, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R
    • Organizer
      5th TERMIS World Congress 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Mouse colonic secretory cells de-differentiate into intestinal stem cells and promote mucosal repair through activation of NF-KB signaling.2018

    • Author(s)
      Ishibashi F, Shimizu H, Kawamoto A, Suzuki K, Anzai S, Kuwabara K, Takahashi J, Nagata S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R
    • Organizer
      ISSCR2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Human colonic organoid treated with inflammatory factors might mimic the pathophysiology of epithelial cells in ulcerative colitis.2018

    • Author(s)
      Hibiya S, Tsuchiya K, Watanabe S, Nishimura R, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02791
  • [Presentation] Ectopic expression of reg3a in the mice distal Colon is mediated by interactions between notch and Il-22 signaling pathways, and promotes tissue repair By the augmentation of EGFR signaling.2018

    • Author(s)
      Ishibashi F, Kuwabara K, Kawamoto A, Anzai S, Takahashi J, Nagata S, Shimizu H, Yui S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Crohn’s disease patient-derived small intestinal organoids reveal diseasestatus related modification of stem cell properties.2018

    • Author(s)
      Suzuki K, Takahashi J, Hiraguri Y, Yui S, Shimizu H, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
    • Organizer
      5th TERMIS World Congress 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Human colonic organoid treated with inflammatory factors might mimic the pathophysiology of epithelial cells in ulcerative colitis.2018

    • Author(s)
      Hibiya S, Tsuchiya K, Watanabe S, Nishimura R, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Lesion-specific gene expression in the Epithelial cells of Crohn’s disease by comparing Small intestinal organoids from active and inactive Lesion in the same patient.2018

    • Author(s)
      Hibiya S, Tsuchiya K, Nishimura R, Shirasaki T, Watanabe S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19535
  • [Presentation] Long-lived secretory cells residing in the mouse proximal colon serve as reserve stem cells under DNA damage-induced mucosal injury.2018

    • Author(s)
      Kuwabara K, Ishibashi F, Kawamoto A, Anzai S, Takahashi J, Nagata S, Shimizu H, Yui S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R
    • Organizer
      UEGW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Single-cell level analysis of organoids derived from CD patients reveals disease-status related modifications of small intestinal stem cells.2018

    • Author(s)
      Suzuki K, Kuwabara K, Takahashi J, Anzai S, Kuno R, Kawamoto A, Ishibashi F, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
    • Organizer
      DDW 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Atoh1 protein stability in sporadic colon cancer and colitis-associated cancer2017

    • Author(s)
      Tsuchiya K
    • Organizer
      BIT’s 10th Anniversary of Protein & Peptide Conference-2017
    • Place of Presentation
      Hilton Fukuoka Sea Hawk(Japan)
    • Year and Date
      2017-03-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] 消化管幹細胞研究の最前線2017

    • Author(s)
      土屋輝一郎
    • Organizer
      第13回日本消化管学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2017-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15287
  • [Presentation] Lineage tracing reveals contribution of Atoh1+ cell-derived stem cells in the homeostasis, repair, and carcinogenesis of the intestinal epithelium2017

    • Author(s)
      Ishibashi F, Shimizu H, Nakata T, Fujii S, Suzuki K, Kawamoto A, Anzai S, Kuno R, Nagata S, Ito G, Murano T, Oshima S, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M
    • Organizer
      DDW2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 炎症性腸疾患に付随するがんの病態解明2017

    • Author(s)
      土屋 輝一郎、渡辺 守
    • Organizer
      JDDW2017
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Establishment of a colonic oranoid with Wnt-independent growth by long-term inflammatory stimulation.2017

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Mamoru Watanabe
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] バルーン内視鏡生検検体を用いたクローン病病態解析.2017

    • Author(s)
      土屋輝一郎、渡辺 守.
    • Organizer
      第35回サイトプロテクション研究会
    • Place of Presentation
      メルパルク京都(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] TP53 mutation acquires higher malignant potential in human colon cancer cells2017

    • Author(s)
      Watanabe S, Tsuchiya K, Shirasaki T, Hibiya S, Oshima S, Nakamura T, Nishimura R, Okamoto R, Watanabe M.
    • Organizer
      UEGW2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Reprogrammed Atoh1+ intestinal epithelial cells contribute to regenerate damaged colonic mucosa in DSS-induced colitis.2017

    • Author(s)
      Ishibashi F, Shimizu H, Nakata T, Fujii S, Suzuki K, Kawamoto A, Anzai S, Kuno R, Nagata S, Ito G, Murano T, Oshima S, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M
    • Organizer
      UEGW2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 消化管幹細胞研究の最前線.2017

    • Author(s)
      土屋輝一郎
    • Organizer
      第13回日本消化管学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2017-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Construction of in vitro model of ulcerative colitis using mouse primary colonic organoid2016

    • Author(s)
      Hibiya S, Tsuchiya K, Watanabe S, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      UEGW2016
    • Place of Presentation
      ウィーン(オーストリア)
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Mouse colonic organoid acquires wnt-independent survival property after long-term inflammation.2016

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      AOCC2016
    • Place of Presentation
      Kyoto International Conference Center, Kyoto(JAPAN)
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Single-Cell Level Analysis Reveals Heterogeneous Expression of Stem-Cell Specific Genes in Human Small Intestinal Organoids2016

    • Author(s)
      Suzuki K, Fujii S, Kawamoto A, Ishibashi F, Nakata T, Ito G, Shimizu H, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
    • Organizer
      DDW2016
    • Place of Presentation
      サンディエゴ(アメリカ)
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] ATOH1 Protein Stabilization in Tumor Acquires the Morphological Change to Signet Ring Cell Carcinoma With Cancer Stem Cell Enrichment in Colon Cancer.2016

    • Author(s)
      Tsuchiya K, Hibiya S, Fukushima K, Shirasaki T, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2016
    • Place of Presentation
      サンディエゴ(アメリカ)
    • Year and Date
      2016-05-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Atoh1 protein stabilization in colon tumor acquires the phenotype of signet ring cell carcinoma with cancer stem cell enrichment.2016

    • Author(s)
      Kiichiro Tsuchiya, Shuji Hibiya, Keita Fukushima, Tomoaki Shirasaki, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      AOCC2016
    • Place of Presentation
      Kyoto International Conference Center, Kyoto(JAPAN)
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] 小腸内視鏡生検検体を用いたクローン病におけるα defensin 発現解析.2016

    • Author(s)
      林 亮平、土屋輝一郎、渡辺 守.
    • Organizer
      第102回日本消化器病学会総会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Construction of in vitro model of ulcerative colitis using mouse primary colonic organoid.2016

    • Author(s)
      Hibiya S, Tsuchiya K, Watanabe S, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M.
    • Organizer
      UEGW2016
    • Place of Presentation
      Vienna(Austria)
    • Year and Date
      2016-10-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] In Vitro organoid model reveals PGF2 as a Robust Mediator of chloride & water secretion bt human intestinal epithelial cells.2016

    • Author(s)
      Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Nakata T, Ito G, Shimizu H, Mizutani T, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
    • Organizer
      DDW2016
    • Place of Presentation
      サンディエゴ(アメリカ)
    • Year and Date
      2016-05-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 炎症関連大腸がんにおけるがん幹細胞形質獲得機構2016

    • Author(s)
      土屋 輝一郎
    • Organizer
      日本がん分子標的治療学会 第11回トランスレーショナルリサーチワークショップ
    • Place of Presentation
      都市センターホテル(東京都千代田区)
    • Year and Date
      2016-01-15
    • Data Source
      KAKENHI-PROJECT-15K15287
  • [Presentation] ヒトLgr5 発現可視化による粘液産生大腸癌ニッチ解析2016

    • Author(s)
      福島啓太、土屋輝一郎、加納嘉人、白崎友彬、日比谷秀爾、岡本隆一、中村哲也、渡辺 守.
    • Organizer
      第102回日本消化器病学会総会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] ATOH1 Protein stabillzation in tumor acquires the morphological change to signet ring cell enrichment in colon cancer.2016

    • Author(s)
      Kiichiro Tsuchiya, Shuji Hibiya, Keita Fukushima, Tomoaki Shirasaki, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      DDW2016
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Construction of in vitro model for inflammatory bowel disease using primary colonic organoid.2016

    • Author(s)
      Syuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      DDW2016
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] 生検検体が切り拓くIBD病態解明と臨床展開.2016

    • Author(s)
      土屋輝一郎
    • Organizer
      第14回 広島消化器免疫研究会
    • Place of Presentation
      ホテルグランヴィア広島(広島県広島市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] 炎症性腸疾患関連大腸がんの形質獲得機構2016

    • Author(s)
      土屋輝一郎
    • Organizer
      お茶の水がん学アカデミア124回集会
    • Place of Presentation
      順天堂大学(東京都文京区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Atoh1 protein stabilization in colon tumor acquires the morphological change to signet ring cell carcinoma with cancer stem cell enrichment.2016

    • Author(s)
      Tsuchiya K, Hibiya S, Fukushima K, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M.
    • Organizer
      APDW2016
    • Place of Presentation
      Kobe convention center, KOBE(JAPAN)
    • Year and Date
      2016-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Stimulation with the ligands of Toll like receptors in primary human organoids.2016

    • Author(s)
      Tomoaki Shirasaki, Kiichiro Tsuchiya, Shuji Hibiya, Ryu Nishimura, Keita Fukushima, Sho Watanabe, Ryuichi Okamoto, Tetsuya Nakamura and Mamoru Watanabe.
    • Organizer
      AOCC2016
    • Place of Presentation
      Kyoto International Conference Center, Kyoto(JAPAN)
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] OLFM4 and UBD are up-regulated in the inflamed intestinal epithelia of IBD patients by synergy of Notch signaling and TNF-α2016

    • Author(s)
      Kawamoto A, Ito G, Nakata T, Fujii S, Suzuki K, Ishibashi F, Shimizu H, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M
    • Organizer
      AOCC 2016
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2016-07-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 長期炎症刺激による大腸上皮培養細胞の非可逆的NF κB シグナル活性.2016

    • Author(s)
      日比谷秀爾、土屋輝一郎、白崎友彬、福島啓太、大島 茂、岡本隆一、中村哲也、渡辺 守.
    • Organizer
      第102回日本消化器病学会総会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Mouse colonic organoid acquires wnt-independent survival property after long-term inflammation2016

    • Author(s)
      Hibiya S, Tsuchiya K, Shirasaki T, Fukushima K, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      AOCC 2016
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Stimulation with the ligands of toll like receptors in primary human organoids2016

    • Author(s)
      Shirasaki T, Tsuchiya K, Hibiya S, Nishimura R, Watanabe S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      AOCC 2016
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2016-07-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] 炎症関連大腸がんにおけるがん幹細胞形質獲得機構2016

    • Author(s)
      土屋 輝一郎
    • Organizer
      日本がん分子標的治療学会 第11回トランスレーショナルリサーチワークショップ
    • Place of Presentation
      都市センターホテル(東京都千代田区)
    • Year and Date
      2016-01-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Atoh1 protein stabilization in colon tumor acquires the morphological change to signet ring cell carcinoma with cancer stem cell enrichment.2016

    • Author(s)
      Tsuchiya K, Hibiya S, Fukushima K, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      APDW2016
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2016-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Jagged1 is Indispensable for the Maintenance of Tumor Stem Cell Niche in APC-Deficient Intestinal Adenomas2016

    • Author(s)
      Nakata T, Ito G, Shimizu H, Fujii S, Suzuki K, Ishibashi F, Kawamoto A, Tsuchiya K, Nakamura T, Hozumi K, Okamoto R, Watanabe M
    • Organizer
      DDW2016
    • Place of Presentation
      サンディエゴ(アメリカ)
    • Year and Date
      2016-05-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Construction of In Vitro Model for Inflammatory Bowel Disease Using Primary Colonic Organoid2016

    • Author(s)
      Hibiya S, Tsuchiya K, Shirasaki T, Fukushima K, Oshima S, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2016
    • Place of Presentation
      サンディエゴ(アメリカ)
    • Year and Date
      2016-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Contiuous stimulation with cytokines leads to irreversible activation of NF-kB signaling in colonic epithelial cells by organoid culture.2015

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, M. Watanabe
    • Organizer
      UEGW2015.
    • Place of Presentation
      Barcelona(Spain)
    • Year and Date
      2015-10-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Contiuous stimulation with cytokines leads to irreversible activation of NF-γb signaling in colonic epithelial cells by organoid culture.2015

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima ,Ryuichi Okamoto, Tetsuya Nakamura,Mamoru Watanabe
    • Organizer
      UEGW2015
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-10-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Human alpha-Defensin 6 regulated by the cooperation of beta-catenin and Atoh1, might be the pathogenesis of Crohn’s Disease.2015

    • Author(s)
      Hayashi R, Tsuchiya K, Hibiya S, Fukushima K, Horita N, Okada E, Araki A, Ohtsuka K, Watanabe M
    • Organizer
      Digestive Disease Week 2015
    • Place of Presentation
      Washington D.C.(USA)
    • Year and Date
      2015-05-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460945
  • [Presentation] Distinct Role of Notch Ligands, DLL1 and Dll4, in Normal and in Tumor Intestinal Epithelium.2015

    • Author(s)
      Toru Nakata, Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.
    • Organizer
      DDW 2015
    • Place of Presentation
      ワシントン(米国)
    • Year and Date
      2015-05-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Mapping biopsy of entire small intestine revealed specific gene expression in Crohn’s disease2015

    • Author(s)
      Kiichiro Tsuchiya, Ryohei Hayashi, Shuji Hibiya, Keita Fukushima, Nobukatsu Horita, Tomoaki Shirasaki, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Mamoru Watanabe
    • Organizer
      UEG Week 2015
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] The Acquisition of Cancer Stemness by Atoh1 in Colitis Associated Cancer2015

    • Author(s)
      Kiichiro Tsuchiya, Keita Fukushima, Mamoru Watanabe
    • Organizer
      8th Annual World Congress of Regenerative Medicine & Stem Cells
    • Place of Presentation
      釜山(韓国)
    • Year and Date
      2015-03-21
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.2015

    • Author(s)
      Kohei Suzuki, Satoru Fujii, Toru Nakata, Ami Kawamoto, Fumiaki Ishibashi, Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya, Kazuo Otsuka,Tetsuya Nakamura, Ryuichi Okamoto, M. Watanabe
    • Organizer
      DDW 2015
    • Place of Presentation
      Washington,D.C.(U.S.A.)
    • Year and Date
      2015-05-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Atoh1 Protein Expression by TNF-a and the Acquisition of Malignant Potential in Colitis- Associated Colorectal Cancer.2015

    • Author(s)
      Keita Fukushima, Kiichiro Tsuchiya, Shuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Yoshihito Kano, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      DDW 2015
    • Place of Presentation
      ワシントン(米国)
    • Year and Date
      2015-05-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Establishment of a 3D cell culture-based screening platform to identify natural products that can regulate transepithelial water transport of the human gastrointestinal tract.2015

    • Author(s)
      Fujii Satoru, Okamoto Ryuichi, Nakata Toru, Suzuki Kohei, Ishibashi Fumiaki, Kawamoto Ami, Segawa Sayaka-Ohashi, Mizutani Tomohiro, Tsuchiya Kiichiro, Nakamura Tetsuya, Mamoru Watanabe
    • Organizer
      Pacifichem2015
    • Place of Presentation
      Hawaii(U.S.A.)
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] Mapping biopsy of entire small intestine is useful to assess the pathogenesis of Crohn’s disease.2015

    • Author(s)
      Kiichiro Tsuchiya, Ryohei Hayashi Mamoru Watanabe
    • Organizer
      AOCC2015
    • Place of Presentation
      北京(中国)
    • Year and Date
      2015-06-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Atoh1 protein stabilized by TNF-α acquires enhanced malignant potential in colitis-associated colorectal cancer.2015

    • Author(s)
      Tomoaki Shirasaki, Keita Fukushima, Kiichiro Tsuchiya, Shuuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      AOCC2015
    • Place of Presentation
      北京(中国)
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Acquisition of enhanced malignant potential in inflammation associated colon cancer2015

    • Author(s)
      Kiichiro Tsuchiya, Shuji Hibiya, Mamoru Watanabe
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15287
  • [Presentation] Continuous Stimulation With Cytokines Leads to Irreversible Accumulation of NF-kB Signaling in Colonic Epithelial Cells.2015

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, M. Watanabe
    • Organizer
      DDW 2015
    • Place of Presentation
      Washington,D.C.(U.S.A.)
    • Year and Date
      2015-05-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] The Acquisition of Cancer Stemness by Atoh1 in Colitis Associated Cancer2015

    • Author(s)
      Kiichiro Tsuchiya, Keita Fukushima, Mamoru Watanabe
    • Organizer
      8th Annual World Congress of Regenerative Medicine & Stem Cells
    • Place of Presentation
      釜山(韓国)
    • Year and Date
      2015-03-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] A novel fluorescent labelling system into small intestinal organoid reveals independent long-lived intestinal stem cells in a crypt.2015

    • Author(s)
      Nobuyuki Horita, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Masayoshi Fukuda, Tomohiro Mizutani, Ryuichi Okamoto, Testuya Nakamura and M. Watanabe
    • Organizer
      AOCC2015
    • Place of Presentation
      北京(China)
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221307
  • [Presentation] A novel fluorescent labelling system into small intestinal organoid reveals independent long-lived intestinal stem cells in a crypt.2015

    • Author(s)
      Horita N,Tsuchiya K,Hayashi R,Fukushima K,Hibiya S,Fukuda M,Mizutani T,Okamoto R,Nakamura T and Watanabe M.
    • Organizer
      AOCC2015
    • Place of Presentation
      北京(中国)
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] TNF-α stabilizes atoh1 protein in colitis-associated colorectal cancer resulting in enhanced malignant potential.2015

    • Author(s)
      Tomoaki Shirasaki, Keita Fukushima, Kiichiro Tsuchiya, Shuuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      UEGW2015
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-10-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Establishment of a 3D cell culture-based screening platform to identify natural products that can regulate transepithelial water transport of the human gastrointestinal tract.2015

    • Author(s)
      Satoru Fujii, Ryuichi Okamoto, Toru Nakata, Kohei Suzuki, Fumiaki Ishibashi, Ami Kawamoto,Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      Pacifichem2015
    • Place of Presentation
      ハワイ(米国)
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Mapping biopsy of entire small intestine revealed specific gene expression in Crohn’s disease2015

    • Author(s)
      Kiichiro Tsuchiya, Ryohei Hayashi, Shuji Hibiya, Keita Fukushima, Nobukatsu Horita, Tomoaki Shirasaki, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Mamoru Watanabe
    • Organizer
      UEG Week 2015
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15287
  • [Presentation] Notch Ligands DLL1 and Dll4 Are Expressed by Distinct Population of Epithelial Cells in the Mice Intestine.2015

    • Author(s)
      Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Toru Nakata, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.
    • Organizer
      DDW 2015
    • Place of Presentation
      ワシントン;米国
    • Year and Date
      2015-05-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Acquisition of enhanced malignant potential in inflammation associated colon cancer2015

    • Author(s)
      Kiichiro Tsuchiya, Shuji Hibiya, Mamoru Watanabe
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04808
  • [Presentation] Mapping biopsy of entire small intestine is useful to assess the pathogenesis of Crohn’s disease.2015

    • Author(s)
      Kiichiro Tsuchiya, Ryohei Hayashi Mamoru Watanabe
    • Organizer
      AOCC2015
    • Place of Presentation
      北京(中国)
    • Year and Date
      2015-06-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15287
  • [Presentation] The Acquisition of Cancer Stemness by Atoh1 in Colitis Associated Cancer2015

    • Author(s)
      Kiichiro Tsuchiya, Keita Fukushima, Mamoru Watanabe
    • Organizer
      8th Annual World Congress of Regenerative Medicine & Stem Cells
    • Place of Presentation
      釜山(韓国)
    • Year and Date
      2015-03-21
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Continuous Stimulation With Cytokines Leads to Irreversible Accumulation of NF-kB Signaling in Colonic Epithelial Cells.2015

    • Author(s)
      Shuji Hibiya, Kiichiro Tsuchiya, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      DDW 2015
    • Place of Presentation
      ワシントン(米国)
    • Year and Date
      2015-05-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.2015

    • Author(s)
      Kohei Suzuki,Satoru Fujii,Toru Nakata,Ami Kawamoto,Fumiaki Ishibashi,Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya,Kazuo Otsuka,Tetsuya Nakamura,Ryuichi Okamoto,Mamoru Watanabe.
    • Organizer
      AOCC2015
    • Place of Presentation
      北京(中国)
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Molecular mechanism in the pathogenesis of the colitis-associated colorectal cancer.2014

    • Author(s)
      Tsuchiya K
    • Organizer
      The 32th Annual Meeting of Japanese Society for Cytoprotection & Cytobiology
    • Place of Presentation
      Kyoto, Japan
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Innate immune spiral of intestinal epithelial cells by the long-term inflammation.2014

    • Author(s)
      Tsuchiya K, Hibiya S, Watanabe M
    • Organizer
      The 73rd Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Notch signaling and TNF-α synergistically up-regulates expression of OLFM4 in human intestinal epithelial cells.2014

    • Author(s)
      Go Ito, Ryuichi Okamoto, Tasturo Murano, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe .
    • Organizer
      第8回Japan-US Collabaration Conference in Gastroenterology
    • Place of Presentation
      Intercontinental TOKYO BAY (東京都港区海岸1-16-2)
    • Year and Date
      2014-11-21
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Molecular mechanism in the pathogenesis of the colitis-associated colorectal cancer.2014

    • Author(s)
      Tsuchiya K
    • Organizer
      The 32th Annual Meeting of Japanese Society for Cytoprotection & Cytobiology
    • Place of Presentation
      Kyoto, Japan
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Innate immune spiral of intestinal epithelial cells by the long-term inflammation.2014

    • Author(s)
      Tsuchiya K, Hibiya S, Watanabe M
    • Organizer
      The 73rd Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Notch signaling and TNF-α synergistically promotes intracellular protein expression of OLFM4 in human intestinal epithelial cells.2014

    • Author(s)
      Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      The 2nd Annual Meeting of Asian Organization for Crohn's and Colitis
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2014-06-21
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Molecular mechanism in the pathogenesis of the colitis-associated colorectal cancer2014

    • Author(s)
      Tsuchiya K
    • Organizer
      The 32th Annual Meeting of Japanese Society for Cytoprotection & Cytobiology
    • Place of Presentation
      Kyoto, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Distinct Expression Patterns of Notch Ligands, DLL1 and DLL4, in Normal and Inflamed Mice Intestine.2014

    • Author(s)
      Hiromichi Shimizu, Ryuichi Okamoto, Go Ito, Satoru Fujii, Toru Nakata, Kohei Suzuki, Tatsuro Murano, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe.
    • Organizer
      The 2nd Annual Meeting of Asian Organization for Crohn's and Colitis
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2014-06-21
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Innate immune spiral of intestinal epithelial cells by the long-term inflammation.2014

    • Author(s)
      Tsuchiya K, Hibiya S, Watanabe M:
    • Organizer
      The 73rd Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Notch Signaling and TNF-alpha synergistically promotes intracellular protein accumulation of olfm4 in the inflamed mucosa of ulcerative colitis.2014

    • Author(s)
      Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
    • Organizer
      UEGW2014
    • Place of Presentation
      Vienna (Austria)
    • Year and Date
      2014-10-21
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Cancer Stemness In Mucinous Colon Cancer.2013

    • Author(s)
      Tsuchiya K, Kano Y, Watanabe M
    • Organizer
      BIT's 6th Annual World Congress of Regenerative Medicine & Stem Cells-2013
    • Place of Presentation
      大連、中国
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Live imaging of single cell reveals single stem cell dynamics in an organoid derived from murine small intestine.2013

    • Author(s)
      Horita N, Tsuchiya K, Hibiya S, Fukushima K, Kano Y, Xiu Zheng, Okamoto R, Nakamura T , Watanabe M
    • Organizer
      DDW2013
    • Place of Presentation
      Orland,USA
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Atoh1発現大腸癌における幹細胞形質獲得とニッチ形成2013

    • Author(s)
      加納嘉人、土屋輝一郎、渡辺 守
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] 全小腸マッピング生検検体を用いた網羅的遺伝子発現解析によるクローン病特異的遺伝子の同定2013

    • Author(s)
      堀田伸勝、土屋輝一郎、渡辺 守
    • Organizer
      第85回 日本消化器内視鏡学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] 全小腸マッピング生検によるクローン病病態解析2013

    • Author(s)
      土屋輝一郎、堀田伸勝、林 亮平、日比谷秀爾、福島啓太、加納嘉人、渡辺 守
    • Organizer
      第51回 小腸研究会
    • Place of Presentation
      名古屋、名古屋国際会議場
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Live imaging of single cell reveals single stem cell dynamics in an organoid derived from murine small intestine.2013

    • Author(s)
      Horita N, Tsuchiya K, Hibiya S, Fukushima K, Kano Y, Xiu Zheng, Okamoto R, Nakamura T , Watanabe M
    • Organizer
      DDW2013
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] 炎症関連大腸がんにおける悪性形質獲得機構解析2013

    • Author(s)
      土屋輝一郎
    • Organizer
      がん研究分野の特性等を踏まえた支援活動 公開シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] 炎症関連大腸がんにおける悪性形質獲得機構解析2013

    • Author(s)
      土屋輝一郎
    • Organizer
      がん研究分野の特性等を踏まえた支援活動 公開シンポジウム.
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] 消化管幹細胞と消化器癌幹細胞2013

    • Author(s)
      土屋輝一郎
    • Organizer
      第110回 日本内科学会講演会.
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Cancer Stemness In Mucinous Colon Cancer.2013

    • Author(s)
      Tsuchiya K, Kano Y, Watanabe M
    • Organizer
      BIT's 6th Annual World Congress of Regenerative Medicine & Stem Cells-2013.
    • Place of Presentation
      大連、中国
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] 消化管幹細胞と消化器癌幹細胞2013

    • Author(s)
      土屋輝一郎
    • Organizer
      第110回 日本内科学会講演会
    • Place of Presentation
      東京、東京国際フォーラム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Live imaging of single cell reveals single stem cell dynamics in an organoid derived from murine small intestine2013

    • Author(s)
      Horita N, Tsuchiya K, Hibiya S, Fukushima K, Kano Y, Xiu Zheng, Okamoto R, Nakamura T , Watanabe M
    • Organizer
      DDW2013
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Cancer Stemness In Mucinous Colon Cancer.2013

    • Author(s)
      Tsuchiya K, Kano Y, Watanabe M
    • Organizer
      BIT's 6th Annual World Congress of Regenerative Medicine & Stem Cells-2013.
    • Place of Presentation
      大連、中国
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] 白血球除去療法(LCAP)による潰瘍性大腸炎の治療戦略2013

    • Author(s)
      土屋輝一郎
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Stabilization of Atoh1 protein by TNF-α in colitic cancer might acquire the cancer stemness.DDW20132013

    • Author(s)
      Tsuchiya K, Fukushima K, Kano Y, Hibiya S, Horita N, Xiu Zheng, Okamoto R,Nakamura T, Watanabe M
    • Organizer
      DDW2013
    • Place of Presentation
      Orland,USA
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] 全小腸マッピング生検によるクローン病病態解析2013

    • Author(s)
      土屋輝一郎、堀田伸勝、林 亮平、日比谷秀爾、福島啓太、加納嘉人、渡辺 守
    • Organizer
      第51回 小腸研究会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] 白血球除去療法(LCAP)による潰瘍性大腸炎の治療戦略2013

    • Author(s)
      土屋輝一郎
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Atoh1 protein stabilization acquired cancer stem cell phenotype and niche in colon cancer2013

    • Author(s)
      Kano Y, Tsuchiya K, Okamoto R, Nakamura T: Watanabe M
    • Organizer
      GI Research Academy
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] NSAIDs服用患者における全長小腸粘膜の病理学的検討2013

    • Author(s)
      岡田英理子、土屋輝一郎、岩嵜美智子、堀田伸勝、福島啓太、日比谷秀爾、加納嘉人、大塚和朗、荒木昭博、渡辺 守
    • Organizer
      第85回 日本消化器内視鏡学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25460945
  • [Presentation] Atoh1発現大腸癌における幹細胞形質獲得とニッチ形成2013

    • Author(s)
      加納嘉人、土屋輝一郎、渡辺 守
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Stabilization of Atoh1 protein by TNF-α in colitic cancer might acquire the cancer stemness.DDW20132013

    • Author(s)
      Tsuchiya K, Fukushima K, Kano Y, Hibiya S, Horita N, Xiu Zheng, Okamoto R,Nakamura T, Watanabe M
    • Organizer
      DDW2013
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] 消化管幹細胞と消化器癌幹細胞2013

    • Author(s)
      土屋輝一郎
    • Organizer
      第110回 日本内科学会講演会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Atoh1proteinstabilizationacquiredcancerstemcell phenotype and niche in colon cancer.2013

    • Author(s)
      Kano Y, Tsuchiya K, Watanabe M
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Atoh1proteinstabilizationacquiredcancerstemcell phenotype and niche in colon cancer.2013

    • Author(s)
      Kano Y, Tsuchiya K, Watanabe M
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Atoh1proteinstabilizationacquiredcancerstemcell phenotype and niche in colon cancer2013

    • Author(s)
      Kano Y, Tsuchiya K, Watanabe M
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] 全小腸マッピング生検によるクローン病病態解析2013

    • Author(s)
      土屋輝一郎、堀田伸勝、林 亮平、日比谷秀爾、福島啓太、加納嘉人、渡辺 守
    • Organizer
      第51回 小腸研究会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] 全小腸マッピング生検検体を用いた網羅的遺伝子発現解析によるクローン病特異的遺伝子の同定2013

    • Author(s)
      堀田伸勝、土屋輝一郎、渡辺 守
    • Organizer
      第85回 日本消化器内視鏡学会総会
    • Place of Presentation
      京都、京都国際会館
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] Atoh1 protein stabilization acquired cancer stem cell phenotype and niche in colon cancer2013

    • Author(s)
      Kano Y, Tsuchiya K, Okamoto R, Nakamura T: Watanabe M
    • Organizer
      GI Research Academy 2013
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] 白血球除去療法(LCAP)による潰瘍性大腸炎の治療戦略2013

    • Author(s)
      土屋輝一郎
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Atoh1発現大腸癌における幹細胞形質獲得とニッチ形成2013

    • Author(s)
      加納嘉人、土屋輝一郎、渡辺 守
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Atoh1 protein stabilization acquired cancer stem cell phenotype and niche in colon cancer2013

    • Author(s)
      Kano Y, Tsuchiya K, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      GI Research Academy 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] 炎症関連大腸がんにおける悪性形質獲得機構解析2013

    • Author(s)
      土屋輝一郎
    • Organizer
      がん研究分野の特性等を踏まえた支援活動 公開シンポジウム.
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25114703
  • [Presentation] 全小腸マッピング生検検体を用いた網羅的遺伝子発現解析によるクローン病特異的遺伝子の同定2013

    • Author(s)
      堀田伸勝、土屋輝一郎、渡辺 守
    • Organizer
      第85回 日本消化器内視鏡学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PUBLICLY-25130704
  • [Presentation] Stabilization of Atoh1 protein by TNF-α in colitic cancer might acquire the cancer stemness2013

    • Author(s)
      Tsuchiya K, Fukushima K, Kano Y, Hibiya S, Horita N, Xiu Zheng, Okamoto R,Nakamura T, Watanabe M
    • Organizer
      DDW2013
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Flagellin response via TLR5 on basolateral membrane of primary intestinal epithelial cells is regulated by Notch signaling.2012

    • Author(s)
      Tsuchiya K, Zheng X, Kano Y, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2012
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] The stabilization of Atoh1 protein in colitic cancer induces cancer stemness and chemoresistance.2012

    • Author(s)
      Tsuchiya K, Kano Y, Watanabe M
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] The acquisition of cancer stemness in colon cancer by the Atoh1 protein stabilization.2012

    • Author(s)
      Kano Y, Tsuchiya K, Horita N, Zheng X, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2012
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] The stabilization of Atoh1 protein in colon cancer acquires cancer stemness and chemoresistance.2012

    • Author(s)
      Tsuchiya K, Kano Y, Mizutani T, Yui S, Nakamura T, Watanabe M
    • Organizer
      第10回 幹細胞シンポジウム.
    • Place of Presentation
      淡路島
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] 大腸における幹細胞維持とがん幹細胞発現機構2012

    • Author(s)
      土屋輝一郎、加納嘉人、中村哲也、渡辺 守
    • Organizer
      第44回日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      高知
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] The acquisition of cancer stemness in colon cancer by the Atoh1 protein stabilization.2012

    • Author(s)
      Kano Y, Tsuchiya K, Horita N, Zheng X, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2012
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] The stabilization of Atoh1 protein in colon cancer acquires cancer stemness and chemoresistance.2012

    • Author(s)
      Tsuchiya K, Kano Y, Mizutani T, Yui S, Nakamura T, Watanabe M
    • Organizer
      第10回 幹細胞シンポジウム
    • Place of Presentation
      淡路島
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] Intestinal stem cells and cancer stem cells.2012

    • Author(s)
      Tsuchiya K
    • Organizer
      Cancer Stem Cell Symposium
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] 大腸における幹細胞維持とがん幹細胞発現機構2012

    • Author(s)
      土屋輝一郎、加納嘉人、中村哲也、渡辺 守
    • Organizer
      第44回日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      高知
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Intestinal stem cells and cancer stem cells.2012

    • Author(s)
      Tsuchiya K
    • Organizer
      Cancer Stem Cell Symposium
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] The stabilization of Atoh1 protein in colitic cancer induces cancer stemness and chemoresistance.2012

    • Author(s)
      Tsuchiya K, Kano Y, Watanabe M
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] Flagellin response via TLR5 on basolateral membrane of primary intestinal epithelial cells is regulated by Notch signaling.2012

    • Author(s)
      Tsuchiya K, Zheng X, Kano Y, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2012
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24590935
  • [Presentation] Flagellin via TLR5 on basolateral membrane of primary intestinal epithelial cells. (IEC) shows the role of IEC in the response to bacteria2011

    • Author(s)
      Tsuchiya K
    • Organizer
      UEGW2011
    • Place of Presentation
      Stockholm
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] IBDにおける消化管上皮の分化制御と免疫応答2011

    • Author(s)
      土屋輝一郎
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] Cdx2 and Hes1 regulate Hath1 gene expression independently of each other, associating with goblet cell content in Ulcerative Colitis2011

    • Author(s)
      Zheng X, Tsuchiya K
    • Organizer
      DDW 2011
    • Place of Presentation
      Chicago
    • Year and Date
      2011-05-09
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] The stabilization of Atoh1 protein in colorectal cancer mimics raucinous adenocarcinoma2011

    • Author(s)
      土屋輝一郎
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PUBLICLY-23130506
  • [Presentation] ダブルバルーン内視鏡による全小腸マッピング生検の有用性2010

    • Author(s)
      土屋輝一郎、岩嵜美智子、鄭秀、岡本英子、加納嘉人、岡本隆一、中村哲也、荒木昭博、渡辺守
    • Organizer
      第28回大腸検査学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-28
    • Data Source
      KAKENHI-PROJECT-22590694
  • [Presentation] Hes1 via Notch signaling directly suppresses Atoh1/Hath1 gene transcription, resulting in the goblet cell depletion of Ulcerative Colitis.2010

    • Author(s)
      Xiu Zheng, Tsuchiya K, Watanabe M
    • Organizer
      DDW2010
    • Place of Presentation
      New Orleans.
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] The contribution of Atoh1/Hath1 to phenotypic gene expression for Paneth cells.2010

    • Author(s)
      Tsuchiya K, Okamoto R, Watanabe M
    • Organizer
      DDW2010.
    • Place of Presentation
      New Orleans.
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] Silencing of Atoh1 gene expression by Hes1 via Notch signaling results in the goblet cell depletion of Ulcerative Colitis.2010

    • Author(s)
      Tsuchiya K, Okamoto R, Watanabe M
    • Organizer
      14th International Congress of Immunology.
    • Place of Presentation
      Kobe.
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] The contribution of Atoh1/Hath1 to phenotypic gene expression for Paneth cells.2010

    • Author(s)
      Tsuchiya K, Okamoto R, Watanabe M
    • Organizer
      DDW2010
    • Place of Presentation
      New Orleans
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] GSK3 inhibitor induces the intestinal differentiation by the protein stabilization of Atoh12009

    • Author(s)
      Tsuchiya K, et al.
    • Organizer
      DDW2009
    • Place of Presentation
      Chicago
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] Colon carcinogenesis is divided in the undifferentiation and proliferation regulated by Atoh1 and beta-catenin on Wnt signaling, respectively.2009

    • Author(s)
      Tsuchiya K, Okamoto R, Watanabe M
    • Organizer
      UEGW2009.
    • Place of Presentation
      London.
    • Year and Date
      2009-11-23
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] GSK3 inhibitor induces the intestinal differentiation by the protein stabilization of Atohl.2009

    • Author(s)
      Tsuchiya K, Watanabe M, et al.
    • Organizer
      DDW2009
    • Place of Presentation
      Chicago
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Presentation] GSK3 inhibitor induces the intestinal differentiation by the protein stabilization of Atoh12009

    • Author(s)
      Tsuchiya K, Okamoto R, Nakamura T, Watanabe M
    • Organizer
      DDW2009
    • Place of Presentation
      Chicago
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Presentation] Colon carcinogenesis is divided in the undifferentiation and proliferation regulated by Atoh1 and beta-catenin on Wnt signaling, respectively2009

    • Author(s)
      Tsuchiya K, et al.
    • Organizer
      GASTRO2009
    • Place of Presentation
      London
    • Year and Date
      2009-11-23
    • Data Source
      KAKENHI-PROJECT-21790653
  • [Presentation] Notch signaling suppresses the transcriptional activity of Hath1 Gene, resulting in the undifferentiated form of human intestinal epithelial cells.2008

    • Author(s)
      Tsuchiya K, Watanabe M
    • Organizer
      DDW 2008
    • Place of Presentation
      San Diego
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Presentation] Notch signaling suppresses the transcriptional activity of Hath1 Gene, resulting in the undifferentiated form of human intestinal epithelial cells2008

    • Author(s)
      Tsuchiya K, Inoue K, Aragaki M, Okamoto R, Nakamura T, Kanai T, Watanabe M
    • Organizer
      DDW 2008
    • Place of Presentation
      San Diego
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] Notch Signaling suppresses the transcriptional activity of Hathl gene. resulting in the undifferentiated form of human intestinal epithelial cells.2008

    • Author(s)
      Tsuchiya K
    • Organizer
      DDW2008
    • Place of Presentation
      San Diego (U. S. A)
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] Dysregulated differentiation of intestinal epithelia in UC2008

    • Author(s)
      Okamoto R, Tsuchiya K, Nakamura T, Kanai T, Watanabe M
    • Organizer
      3rd Japan-Korea IBD Symposium
    • Place of Presentation
      Korea(Seoul)
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] Notch signaling suppresses the transcriptional activity of Hath1 Gene, resulting in the undifferentiated form of human intestinal epithelial cells2008

    • Author(s)
      Tsuchiya K, Inoue K, Aragaki M, Okamoto R, Nakamura T, Kanai T, Watanabe M
    • Organizer
      DDW2008
    • Place of Presentation
      San Diego
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Presentation] Stabilization of Atohl protein induces Mucin2 gene expression in human colon cancer cells.2007

    • Author(s)
      Tsuchiya K
    • Organizer
      DDW 2007.
    • Place of Presentation
      Washington, D.C
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] Stabilization of Atoh1 protein induces Mucin2 gene expression in human coloncancer cells.2007

    • Author(s)
      Tsuchiya K, Watanabe M
    • Organizer
      DDW 2007.
    • Place of Presentation
      Washington, D.C
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19209027
  • [Presentation] Stabilization of Atoh1 protein induces Mucin2 gene expression in human colon cancer cells2007

    • Author(s)
      Tsuchiya K, Okamoto R, Kanai T, Watanabe M
    • Organizer
      DDW 2007
    • Place of Presentation
      Washington, D.C.
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] Novel Wnt signaling pathway targeting Hathl protein in inverse regulation to β-catenin, suppresses differentiation potency in human colon cancer.2007

    • Author(s)
      Tsuchiya K
    • Organizer
      APDW 2007.
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] Activated notch signaling suppresses generation of goblet cells in the human intestinal mucosa2007

    • Author(s)
      Okamoto R, Tsuchiya K, Kanai T, Watanabe M
    • Organizer
      DDW 2007
    • Place of Presentation
      Washington, D.C.
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19590717
  • [Presentation] COMPLETE CONVERSION OF CRYPT PROGENITOR CELLS INTO ATOH1-POSITIVE CELLS BY TARGETED DELETION OF DLL1 AND DLL4 IN LGR5-POSITIVE INTESTINAL STEM CELLS

    • Author(s)
      H. Shimizu, R. Okamoto, T. Nakata, S. Fujii, G. Ito, T. Murano, K. Tsuchiya, T. Nakamura, M. Watanabe
    • Organizer
      UEGW 2013
    • Place of Presentation
      ベルリン、ドイツ
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Notch signaling regulates expression of Bestrophin-4, a novel enterocyte-specific HCO3-/Cl- channel, in human intestinal epithelial cells.

    • Author(s)
      Go Ito, Ryuichi Okamoto, Satoru Fujii, Hiromichi Shimizu, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
    • Organizer
      DDW 2013
    • Place of Presentation
      オーランド、米国
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] IL-22-MEDIATED ANTIMICROBIAL RESPONSE IS REGULATED BY HES1 VIA STAT3-DEPENDENT TRANSCRIPTION IN HUMAN INTESTINAL EPITHELIAL CELLS

    • Author(s)
      R. Okamoto, T. Murano, H. Shimizu, G. Ito, S. Fujii, T. Nakata, K. Tsuchiya, T. Nakamura, M. Watanabe
    • Organizer
      UEGW 2013
    • Place of Presentation
      ベルリン、ドイツ
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] LINEAGE-SPECIFIC EXPRESSION OF BESTROPHIN-2 AND BESTROPHIN-4 IS REGULATED BY NOTCH SIGNALING IN HUMAN INTESTINAL EPITHELIAL CELLS

    • Author(s)
      G. Ito , R. Okamoto, T. Murano, H. Shimizu, K. Tsuchiya, T. Nakamura, M. Watanabe
    • Organizer
      UEGW 2013
    • Place of Presentation
      ベルリン、ドイツ
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Hes1 promotes IL-22-mediated antimicrobial response through enhancement of STAT3-dependent transcription in human intestinal epithelial cells

    • Author(s)
      Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Satoru Fujii, Kiichiro Tsuchiya, Tetsuya Nakamura, and Mamoru Watanabe
    • Organizer
      The 1st Annual Meeting of Asian Organization for Crohn's and Colitis
    • Place of Presentation
      東京、ラフォーレ東京
    • Data Source
      KAKENHI-PROJECT-25293170
  • [Presentation] Complete conversion of crypt progenitor cells into Atoh1-positive cells by targeted deletion of Dll1 and Dll4 in Lgr5-positive intestinal stem cells

    • Author(s)
      Hiromichi Shimizu, Ryuichi Okamoto, Satoru Fujii, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
    • Organizer
      DDW 2013
    • Place of Presentation
      オーランド、米国
    • Data Source
      KAKENHI-PROJECT-25293170
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    # of Collaborated Projects: 20 results
    # of Collaborated Products: 178 results
  • 2.  NAKAMURA Tetsuya (70265809)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 81 results
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    # of Collaborated Products: 9 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 8 results
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  • 29.  岡田 浩介 (80757526)
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  • 36.  HARA Takahiro
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  • 37.  TORII Satoru
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  • 38.  OSHIMA Hiroko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  NAKAYAMA Mizuho
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  TOTSUKA Teruji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  HINOHARA Kunihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  TAMURA Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  藤井 俊光
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    # of Collaborated Products: 2 results
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    # of Collaborated Products: 5 results
  • 56.  大岡 真也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  櫻井 幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 58.  時野 隆至
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 59.  秋山 好光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 60.  田中 真二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 61.  島田 周
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 62.  佐々木 泰史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 63.  深町 博史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 64.  長沼 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 65.  笹月 健彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 66.  井津井 康浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 67.  板倉 英祐
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 68.  西村 龍
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 69.  佐藤 博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 70.  佐藤 俊朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 71.  河本 亜美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 72.  村川 美也子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 73.  北畑 富貴子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 74.  新田 沙由梨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 75.  越川 直彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 76.  荒瀬 尚
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 77.  後藤 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 78.  榎本 信幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 79.  畠山 鎮次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 80.  渡部 昌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 81.  伊川 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 82.  月田 早智子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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