NAKAMURA Tetsuya 中村哲也

Researcher Number	70265809
Other IDs
Affiliation (Current)	2024: 順天堂大学, 大学院医学研究科, 特任教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 順天堂大学, 大学院医学研究科, 特任教授 2019 – 2020: 順天堂大学, 医学(系)研究科(研究院), 特任教授 2016 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座教授 2015: 東京医科歯科大学, 医歯学(薬)学総合研究科, 寄附講座教授 2015: 東京医科歯科大学, 医歯学総合研究科, 寄附講座教授 … More 2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座教授 2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 2014: 東京医科歯科大学, 医歯学総合研究科, 教授 2014: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座教授 2012 – 2013: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2012 – 2013: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座准教授 2012: 東京医科歯科大学, 医歯学総合研究科, 准教授 2012: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座准教授 2009 – 2011: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 寄附講座教員 2010: 東京医科歯科大学, 医歯学総合研究科, 寄付講座教員 2010: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄付講座教員 2009: 東京医科歯科大学, 医歯学総合研究科, 寄附講座教員 2005: 医科歯科大, 医歯(薬)学総合研究科, 助手 2002 – 2004: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 55010:General surgery and pediatric surgery-related / Biological Sciences / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Organ-based internal medicine and related fields / Gastroenterology / General physiology Except Principal Investigator Gastroenterology / Basic Section 55010:General surgery and pediatric surgery-related / Biological Sciences / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 49030:Experimental pathology-related / Science and Engineering
Keywords	Principal Investigator 再生医療 / 腸上皮幹細胞 / 小腸移植 / 腸再生医療 / オルガノイド移植 / 腸管不全 / 腸オルガノイド / ３次元培養 / 消化管上皮 / IL-7 … More / 短腸症候群 / IRF-2 / IRF-1 / 腸管上皮細胞 / 大腸上皮 / 小腸上皮 / 細胞移植 / 細胞極性 / 上皮極性 / 3次元培養 / 幹細胞移植 / 細胞分化 / 腸上皮置換 / 組織エンジニアリング / GLP-2 / 外科 / 細胞・組織 / 生理学 / 再生医学 / 移植・再生医療 / chronic colitis / transcriptional regulation / intestinal epithelial cell / mucosal immunity / IL-7 receptor / TSLP / IL-7受容体 / 粘膜内リンパ球 / Interferon Regulatory Factor / 遺伝子発現制御 / 腸管粘膜免疫制御 / Interferon Regulatory Factor-2 / Interferon Regulatory Factor-1 / 慢性大腸炎 / 転写制御 / 腸管免疫 / IL-7レセプター / 細胞培養 / 分化転換 / 上皮機能 / 消化管上 / 大腸炎治療 / 組織幹細胞 / 腸管上皮幹細胞 / 消化管再生医療 / 大腸上皮培養 / 炎症性腸疾患 / 再生治療 / 初代培養 / 細胞増殖 / ライブイメージング / 大腸上皮幹細胞 / 細胞移植治療 / 初代培養技術 / ライブセルイメージング / 消化管上皮幹細胞 / Wntシグナル / Notchシグナル / LMP7 / 免疫プロテアソーム / Interferon Reulatory Factor (IRF) / 杯細胞 / 腸管上皮細胞分化 … More Except Principal Investigator 炎症性腸疾患 / 再生医療 / IL-7 / オルガノイド / 粘膜免疫 / Notchシグナル / 腸管上皮 / サイトカイン / Interferon Regulatory Factor (IRF) / 腸管上皮細胞 / 短腸症候群 / 膀胱オルガノイド / 膀胱上皮 / 膀胱拡大術 / 神経因性膀胱 / 創傷治癒 / 細胞治療 / 細胞分化 / 大腸上皮幹細胞 / Wntシグナル / 慢性大腸炎 / 転写因子 / 腸管免疫 / IL-7レセプター / 悪性腫瘍発生 / 腸管利用膀胱膀胱拡大術 / 腸管上皮剥離 / 小腸機能不全 / ヒルシュスプルング病 / 組織工学 / 腸管神経 / 大腸上皮剥離 / オルガノイド培養 / ラット / 移植治療 / Scaffold / 人工小腸 / 免疫不全マウス / ヒト小児腸管オルガノイド / リニエージトレーシング / 陰窩分裂 / 腸上皮幹細胞 / 腸管発達 / オルガノイド移植 / 腸管利用膀胱拡大術 / 経因性膀胱 / 腸上皮置換 / fibroblast growth factor / 分化制御機構 / 悪性腫瘍 / 小腸上皮再生医療 / 腸オルガノイド / 小児短腸症候群 / defined medium / 腸再生医療 / 新生児腸疾患 / ヒト腸上皮オルガノイド / 小腸再生 / 腸上皮オルガノイド / バイオチューブ / 遊離腸管節 / biotube / 小腸上皮オルガノイド / 腸上皮 / 脱分化 / l腸上皮傷害マウスモデル / 腸上皮障害マウスモデル / 生体内イメージング / 腸上皮治癒過程 / in vivoイメージング / 腸上皮細胞脱分化 / 腸上皮治癒 / 腸上皮傷害マウスモデル / 抗原提示 / regenerative medicine / bone marrow cell / transcriptional factor / chronic colitis / cell differentiation / intestinal epithelial cell / mucosal immunity / 食物アレルギー / Il-7レセプター / 骨髄細胞transdifferentiation / 腸管上皮細胞分化 / IL-7レセプター機構 / 粘膜IL-7 / 消化管粘膜免疫 / 骨髄細胞 / 慢性腸炎 / 腸上皮細胞 / 全身制御 / 疑似モデル構築 / 幹細胞機能評価 / 共培養 / 腸内環境 / 発癌モデル / 移植モデル / 大腸移植 / ヒト化マウス / 幹細胞ニッチ / ニッチ / CD66a / クロストーク / 初代培養法 / 薬剤デリバリー / バイオカプセル / ライブ・イメージング / 薬物動態解析 / 薬剤排泄 / 組織再生 / 細胞移植 / 正常腸管上皮 / 粘膜再生 / 上皮幹細胞 / 天然物リガント / 活性評価 / 生体活性評価 / 天然物リガンド / 初代培養 / Lgr-5 / 内視鏡検体 / 抗菌物質 / オートファジー / 幹細胞培養 / 細胞分化機構 / 細胞増殖機構 / 大腸炎 / 体外培養技術 / 組織幹細胞 / 大腸上皮 / 大腸炎創傷治癒 / 幹細胞移植 / 細胞増殖 / 大腸上皮細胞 / Notchシグナル/初代培養/細胞移植治療 / シグナル伝達 / リンパ球 / CEACAM1 / 抗体療法 / 細胞内シグナル伝達 / 免疫制御療法 / 消化管粘膜免疫制御 / 杯細胞分化 / transdifferentiation / 粘膜リンパ球 Less

膀胱上皮化腸管組織のモデル構築に向けたラット膀胱上皮オルガノイド培養の新規開発
- Principal Investigator
  
  須田一人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
Interaction between transplanted enteric neural stem cells and gut extracellular matrix of from pediatric enteric neuropathy patients
- Principal Investigator
  
  澁谷聡一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
マルチカラーレポーターマウスを用いた陰窩複製動態追跡による腸増大機構の解明
- Principal Investigator
  
  松本有加
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
Preventive effect on long-term complications after bladder augmentation cystoplasty by creation of bladder organoid-engrafted intestinal tract
- Principal Investigator
  
  山高篤行
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
新生児・乳児小腸オルガノイド人工小腸を用いた短腸症候群への新規移植治療法の開発
- Principal Investigator
  
  古賀寛之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
Development of technology for in vivo intestinal engineering by transplantation of organoids after epithelial removal by using newly-synthesized chelating agents.Principal Investigator
- Principal Investigator
  
  中村哲也
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
Development of novel treatment strategy for intestinal failure based on generation and transplantation of intestinal organoids capable of GLP-2 secretion in an inducible mannerPrincipal Investigator
- Principal Investigator
  
  Nakamura Tetsuya
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Juntendo University
Development of novel technology for intestinal epithelial replacement with urothelial organoids and its implementation in bladder augmentation
- Principal Investigator
  
  Yamataka Atsuyuki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Juntendo University
in vivo imaging system to analyze the intestinal mucosal healing process through temporarily appearing immature epithelial cells
- Principal Investigator
  
  Matsumoto Yuka
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
Study of the small intestine reproduction with the bowels epithelium organoid and the bloodstream preservation Biotube
- Principal Investigator
  
  Komura Makoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The University of Tokyo
Regenerative potential of human infant small intestinal organoids obtained from surgical specimens
- Principal Investigator
  
  Koga Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
Transplantation of small intestinal organoids onto the colon and its potential as a novel therapeutic approach for intestinal failurePrincipal Investigator
- Principal Investigator
  
  Tetsuya Nakamura
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Juntendo University
  Tokyo Medical and Dental University
Development of hybrid intestine system and its applicationsPrincipal Investigator
- Principal Investigator
  
  Nakamura Tetsuya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Organ-based internal medicine and related fields
- Research Institution
  Tokyo Medical and Dental University
Antigen processing in intestinal epithelial cells
- Principal Investigator
  
  NAGAISHI Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
腸管上皮幹細胞3次元培養技術を利用した管腔形成機構解析Principal Investigator
- Principal Investigator
  
  中村哲也
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
The elucidation of homeostasis regulated by intestinal epithelial stem cells
- Principal Investigator
  
  Watanabe Mamoru
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Development of colitic mucosa repair therapy by the induction of regeneration-specific stem cell niche formation
- Principal Investigator
  
  Okamoto Ryuichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Intestinal epithelial stem cells and their regional identity along the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tetsuya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical and Dental University
The development of the disease model using humanized intestine in mice.
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
独自の正常大腸上皮幹細胞培養技術を用いた管腔形成機構の解析Principal Investigator
- Principal Investigator
  
  中村哲也
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Epithelial regeneration by transplantation of cultured intestinal stem cellsPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tetsuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
CD66a-mediated crosstalk between intestinal epithelia and lymphocytes
- Principal Investigator
  
  NAGAISHI Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Development of a bio-screening method using intestinal epithelial cells
- Principal Investigator
  
  Okamoto Ryuichi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Medical and Dental University
Development of a novel drug-delivery system by a bio-capsule that is built by primary intestinal epithelial cells.
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Designing and Developing Innovative Use of Newly Discovered Colonic Epithelial Culture Method Applicable to Clinical Medicine.
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
独自の培養技術を用いた大腸上皮細胞機能解析と腸炎細胞治療技術の基盤確立
- Principal Investigator
  
  渡辺守
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Real-time imaging analysis of proliferation/differentiation of colonic epithelial cells in primary culturePrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tetsuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Crosstalk between Wnt and Notch signaling in colonic epithelium.
- Principal Investigator
  
  SUZUKI Shinji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
CEACAM1 regulates the cytokine network in intestinal mucosa
- Principal Investigator
  
  NAGAISHI Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
粘膜免疫の特殊性を応用した腸管免疫統御療法の開発
- Principal Investigator
  
  渡辺守
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
腸管粘膜局所IL-7ネットワーク制御応用による新規免疫統御療法開発
- Principal Investigator
  
  渡辺守
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
腸管上皮細胞の分化調節による局所免疫制御機構の解明と慢性大腸炎治療戦略への応用Principal Investigator
- Principal Investigator
  
  中村哲也
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
粘膜免疫の特殊性を応用した腸管免疫統御療法の開発
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Development of a novel therapy for the treatment of chronic colitis based on the manipulation of mucosal immune response and the clarification of tissue specific system for epithelial regeneration.
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the regulatory mechanisms for mucosal immune response by mucosal IL-7/IL-7 receptor systemPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tetsuya
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University

[Book] GI Research2014
- Author(s)
  中村哲也、他
- Total Pages
  7
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24590936
[Book] 分子消化器病2012
- Author(s)
  中村哲也、渡辺　守、他
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24590936
[Book] 内科学2012
- Author(s)
  中村哲也
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-24590936
[Journal Article] Defined serum-free culture of human infant small intestinal organoids with predetermined doses of Wnt3a and R-spondin1 from surgical specimens2021
- Author(s)
  Matsumoto Yuka、Koga Hiroyuki、Takahashi Mirei、Suda Kazuto、Ochi Takanori、Seo Shogo、Miyano Go、Miyake Yuichiro、Nakajima Hideaki、Yoshida Shiho、Mikami Takafumi、Okazaki Tadaharu、Hattori Nobutaka、Yamataka Atsuyuki、Nakamura Tetsuya
- Journal Title
  
  Pediatric Surgery International
  
  Volume: 37 Issue: 11 Pages: 1543-1554
- DOI
  10.1007/s00383-021-04957-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09083
[Journal Article] Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids.2019
- Author(s)
  Nishimura R, Shirasaki T, Tsuchiya K, Miyake Y, Watanabe Y, Hibiya S, Watanabe S, Nakamura T, Watanabe M
- Journal Title
  
  J Gastroenterol.
  
  Volume: in press Issue: 7 Pages: 608-620
- DOI
  10.1007/s00535-018-01540-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-17H06654, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K15930, KAKENHI-PROJECT-19K17425
[Journal Article] Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids.2019
- Author(s)
  Nishimura R, Shirasaki T, Tsuchiya K, Miyake Y, Watanabe Y, Hibiya S, Watanabe S, Nakamura T, Watanabe M
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 54 Pages: 608-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02867
[Journal Article] TP53 mutation by CRISPR system enhances the malignant potential of colon cancer.2019
- Author(s)
  Watanabe S, Tsuchiya K, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
- Journal Title
  
  Mol Cancer Res.
  
  Volume: in press Issue: 7 Pages: 1459-1467
- DOI
  10.1158/1541-7786.mcr-18-1195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-19K17425, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-17H04024
[Journal Article] Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties2018
- Author(s)
  Suzuki Kohei、Murano Tatsuro、Shimizu Hiromichi、Ito Go、Nakata Toru、Fujii Satoru、Ishibashi Fumiaki、Kawamoto Ami、Anzai Sho、Kuno Reiko、Kuwabara Konomi、Takahashi Junichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 9 Pages: 1035-1047
- DOI
  10.1007/s00535-018-1437-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-16K09302, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674
[Journal Article] YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration2018
- Author(s)
  Yui S、Azzolin L、Maimets M、Pedersen MT、Fordham RP、Hansen SL、Larsen HL、Guiu Jordi、Alves MRP、Rundsten CF、Johansen JV、Li Y、Madsen CD、Nakamura T、Watanabe M、Nielsen OH、Schweiger PJ、Piccolo S、Jensen KB
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22 Issue: 1 Pages: 35-49
- DOI
  10.1016/j.stem.2017.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19513
[Journal Article] Recent progress in organoid culture to model intestinal epithelial barrier functions2018
- Author(s)
  Nakamura Tetsuya
- Journal Title
  
  International Immunology
  
  Volume: 31 Issue: 1 Pages: 13-21
- DOI
  10.1093/intimm/dxy065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19674
[Journal Article] B cell activation in the cecal patches during the development of an experimental colitis model.2018
- Author(s)
  Taro Watabe, Takashi Nagaishi, Naoya Tsugawa, Yudai Kojima, Nisha Jose, Akinori Hosoya, Michio Onizawa, Yasuhiro Nemoto, Shigeru Oshima, Tetsuya Nakamura, Hajime Karasuyama, Takahiro Adachi, Mamoru Watanabe
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496 Issue: 2 Pages: 367-373
- DOI
  10.1016/j.bbrc.2018.01.053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-15K08526, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-18K07997, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-17H06170
[Journal Article] Contribution of ATOH1 + Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium2018
- Author(s)
  Ishibashi Fumiaki、Shimizu Hiromichi、Nakata Toru、Fujii Satoru、Suzuki Kohei、Kawamoto Ami、Anzai Sho、Kuno Reiko、Nagata Sayaka、Ito Go、Murano Tatsuro、Mizutani Tomohiro、Oshima Shigeru、Tsuchiya Kiichiro、Nakamura Tetsuya、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Issue: 1 Pages: 27-42
- DOI
  10.1016/j.stemcr.2017.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19513
[Journal Article] Reconstruction of the Human Colon Epithelium In Vivo.2018
- Author(s)
  Sugimoto S, Ohta Y, Fujii M, Matano M, Shimokawa M, Nanki K, Date S, Nishikori S, Nakazato Y, Nakamura T, Kanai T, Sato T.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 22 Issue: 2 Pages: 171-176
- DOI
  10.1016/j.stem.2017.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09325, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-17K15967, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-17J04827
[Journal Article] Advancing Intestinal Organoid Technology Toward Regenerative?Medicine2018
- Author(s)
  Nakamura Tetsuya、Sato Toshiro
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 5 Issue: 1 Pages: 51-60
- DOI
  10.1016/j.jcmgh.2017.10.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19674, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-17H06176
[Journal Article] Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients2018
- Author(s)
  Kawamoto Ami、Nagata Sayaka、Anzai Sho、Takahashi Junichi、Kawai Mao、Hama Minami、Nogawa Daichi、Yamamoto Kouhei、Kuno Reiko、Suzuki Kohei、Shimizu Hiromichi、Hiraguri Yui、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Kitagawa Masanobu、Okamoto Ryuichi、Watanabe Mamoru
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 13 Issue: 4 Pages: 495-509
- DOI
  10.1093/ecco-jcc/jjy180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-18K15774, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-18H02791
[Journal Article] Novel polyubiquitin imaging system, PolyUb-FC, reveals that K33-linked polyubiquitin is recruited by p62/SQSTM1.2017
- Author(s)
  Yoichi Nibe, Shigeru Oshima, Masanori Kobayashi, Chiaki Maeyashiki, Yu Matsuzawa, Kana Otsubo, Hiroki Matsuda, Emi Aonuma, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Shinichiro Nakada, Mamoru Watanabe
- Journal Title
  
  Autophagy.
  
  Volume: 22 Issue: 2 Pages: 1-43
- DOI
  10.1080/15548627.2017.1407889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-16K15423, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-26241014
[Journal Article] Long-term inflammation transforms intestinal epithelial cells of colonic organoids.2017
- Author(s)
  Hibiya S, Tsuchiya K, Hayashi R, Horita N, Watanabe S, Shirasaki T, Nishimura R, Kimura N, Nishimura T, Gotoh N, Oshima S, Okamoto R, Nakamura T, Watanabe M
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 61 Pages: 621-630
- DOI
  10.1093/ecco-jcc/jjw186
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H06770, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-17K15930, KAKENHI-PROJECT-17H06654, KAKENHI-PROJECT-16K09302
[Journal Article] Distinct intestinal adaptation for vitamin B12 and bile acid absorption revealed in a new mouse model of massive ileocecal resection.2017
- Author(s)
  Matsumoto Y, Mochizuki W, Akiyama S, Matsumoto T, Nozaki K, Watanabe M, Nakamura T
- Journal Title
  
  Biol Open.
  
  Volume: 15 Pages: 1364-1374
- DOI
  10.1242/bio.024927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-26221307
[Journal Article] Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors.2017
- Author(s)
  Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 482 Issue: 4 Pages: 1296-1303
- DOI
  10.1016/j.bbrc.2016.12.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284
[Journal Article] HADHA, the alpha subunit of the mitochondrial trifunctional protein,is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells.2017
- Author(s)
  Maeyashiki C, Oshima S, Otsubo K, Kobayashi M, Nibe Y, Matsuzawa Y, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 484 Issue: 3 Pages: 636-641
- DOI
  10.1016/j.bbrc.2017.01.159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-16H06771, KAKENHI-PROJECT-15K15288, KAKENHI-PROJECT-16K15423
[Journal Article] <i>CCN3</i> Expression Marks a Sulfomucin-nonproducing Unique Subset of Colonic Goblet Cells in Mice2017
- Author(s)
  Akiyama S, Mochizuki W, Nibe Y, Matsumoto Y, Sakamoto K, Oshima S, Watanabe M, Nakamura T
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 50 Issue: 6 Pages: 159-168
- DOI
  10.1267/ahc.17027
- NAID
  130006285159
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-26221307
[Journal Article] Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine.2016
- Author(s)
  Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R
- Journal Title
  
  Data Brief.
  
  Volume: 10 Pages: 551-556
- DOI
  10.1016/j.dib.2016.12.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284
[Journal Article] The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development.2016
- Author(s)
  Kobayashi M, Oshima S, Maeyashiki C, Nibe Y, Otsubo K, Matsuzawa Y, Memoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 36780-36780
- DOI
  10.1038/srep36780
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05286, KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-15K15288
[Journal Article] Retinol promotes in vitro growth of proximal colon orgnaoids through a retinoic acid-independent mechanism.2016
- Author(s)
  Matsumoto T, Mochizuki W, Nibe Y, Akiyama S, Matsumoto Y, Nozaki K, Fukuda M, Hayashi A, Mizutani T, Oshima S, Watanabe M, Nakamura T
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 8 Pages: e0162049-e0162049
- DOI
  10.1371/journal.pone.0162049
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26221307
[Journal Article] Co-culture with intestinal epithelial organoids allows efficient expansion and motility analysis of intraepithelial lymphocytes2016
- Author(s)
  Nozaki K, Mochizuki W, Matsumoto Y, Matsumoto T, Fukuda M, Mizutani T, Watanabe M, Nakamura T
- Journal Title
  
  J Gastroenterol
  
  Volume: 51 Issue: 3 Pages: 206-213
- DOI
  10.1007/s00535-016-1170-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112705, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-26221307
[Journal Article] PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells.2016
- Author(s)
  Fujii S, Okamoto R, Suzuki K, Kawamoto A, Ishibashi F, Nakata T, Murano T, Ito G, Shimizu H, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Araki A, Ohtsuka K, Watanabe M
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 36795-36795
- DOI
  10.1038/srep36795
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-16K09302
[Journal Article] CDX2 expression induced by leukocytapheresis might be associated with mucosal healing in ulcerative colitis.2016
- Author(s)
  Tsuchiya K, Hayashi R, Fukushima K, Hibiya S, Horita N, Negi M, Itoh E, Akashi T, Eishi Y, Motoya S, Takeuchi Y, Kunisaki R, Fukunaga K, Nakamura S, Yoshimura N, Takazoe M, Iizuka B, Suzuki Y, Nagahori M, Watanabe M
- Journal Title
  
  J Gastoenterol Hepatol.
  
  Volume: 61 Issue: 5 Pages: 1032-1039
- DOI
  10.1111/jgh.13645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-17H06654
[Journal Article] Reduced human α-defensin 6 in non-inflamed jejunal tissue of Crohn’s disease patients2016
- Author(s)
  Hayashi R , Tsuchiya K, Okamoto R,Watanabe M,et al
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 22 Issue: 5 Pages: 1119-28
- DOI
  10.1097/mib.0000000000000707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16K09302
[Journal Article] TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy.2015
- Author(s)
  Matsuzawa Y, Oshima S, Takahara M, Maeyashiki C, Nemoto Y, Kobayashi M, Nibe Y, Nozaki K, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Averil Ma, Watanabe M
- Journal Title
  
  Autophagy
  
  Volume: 11 Issue: 7 Pages: 1052-1062
- DOI
  10.1080/15548627.2015.1055439
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15288, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-25460946, KAKENHI-PROJECT-25293170
[Journal Article] Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line.2015
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  Keita Fukushima, Kiichiro Tsuchiya,Okamoto Ryuichi, Mamoru Watanabe,et al
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Issue: 8 Pages: 1000-7
- DOI
  10.1111/cas.12703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15286, KAKENHI-PROJECT-15K15287, KAKENHI-PROJECT-15K15288, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-25293170
[Journal Article] Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells2014
- Author(s)
  Murano T, Okamoto R, Ito G, Nakata T, Hibiya S, Shimizu H, Fujii S, Kano Y, Mizutani T, Yui S, Akiyama-Morio J, Nemoto Y, Tsuchiya K, Nakamura T, Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Issue: 3 Pages: 840-846
- DOI
  10.1016/j.bbrc.2013.12.061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524, KAKENHI-PROJECT-26221307
[Journal Article] Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis.2014
- Author(s)
  Suzuki M, Nagaishi T, Yamazaki M, Onizawa M, Watabe T, Sakamaki Y, Ichinose S, Totsuka M, Oshima S, Okamoto R, Shimonaka M, Yagita H, Nakamura T, Watanabe M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e88369-e88369
- DOI
  10.1371/journal.pone.0088369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25670708, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-26460963
[Journal Article] Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine.2014
- Author(s)
  Shimizu H, Okamoto R, Ito G, Nakata T, Suzuki K, Murano T, Mizutani T, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M.
- Journal Title
  
  PeerJ
  
  Volume: 2 Pages: e370-e370
- DOI
  10.7717/peerj.370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25860524
[Journal Article] RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62.2014
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  Y. Matsuzawa , S. Oshima, Y. Nibe, M.Kobayashi, C. Maeyashiki, Y. Nemoto, T. Nagaishi, R. Okamoto R, K. Tsuchiya, T. Nakamura, M. Watanabe.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 456(1) Issue: 1 Pages: 298-304
- DOI
  10.1016/j.bbrc.2014.11.075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25460946, KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-26221307
[Journal Article] Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon2014
- Author(s)
  Fukuda M, Mizutani T, Mochizuki W, Matsumoto T, Nozaki K, Sakamaki Y, Ichinose S, Okada Y, Tanaka T, Watanabe M, Nakamura T
- Journal Title
  
  Genes & Development
  
  Volume: 28(16) Issue: 16 Pages: 1752-1757
- DOI
  10.1101/gad.245233.114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-25670106, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524, KAKENHI-PUBLICLY-26112705, KAKENHI-PROJECT-26221307
[Journal Article] Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt.2014
- Author(s)
  N. Horita, K. Tsuchiya, R. Hayashi, K. Fukushima, S. Hibiya, M. Fukuda, Y. Kano, T. Mizutani, Y. Nemoto, S. Yui, R. Okamoto, T. Nakamura, M. Watanabe
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 454 Issue: 4 Pages: 493-499
- DOI
  10.1016/j.bbrc.2014.10.091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524, KAKENHI-PROJECT-26221307
[Journal Article] Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4+ memory T cells.2013
- Author(s)
  Nemoto Y, Nakamura T, Watanabe M et al
- Journal Title
  
  Gut.
  
  Volume: 62 Issue: 8 Pages: 1142-1152
- DOI
  10.1136/gutjnl-2012-302029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
[Journal Article] Lineage-specific expression of Bestrophin-2 and Bestrophin-4 in human intestinal epithelial cells.2013
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  Ito G, Okamoto R, Nakamura T, Watanabe M et al
- Journal Title
  
  PloS One.
  
  Volume: 8 Issue: 11 Pages: e79693-e79693
- DOI
  10.1371/journal.pone.0079693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25460945, KAKENHI-PROJECT-25461031, KAKENHI-PROJECT-25670367, KAKENHI-PROJECT-25860524
[Journal Article] Randomised clinical trial: evaluation of the efficacy of mesalazine (mesalamine) suppositories in patients with ulcerative colitis and active rectal inflammation -- a placebo-controlled study.2013
- Author(s)
  Watanabe M, Nishino H, Sameshima Y, Ota A, Nakamura S, Hibi T
- Journal Title
  
  Aliment pharmacol ther
  
  Volume: 38 Issue: 3 Pages: 264-273
- DOI
  10.1111/apt.12362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-24590936
[Journal Article] IL-7 promotes long-term in vitro survival of unique long-lived memory subset generated from mucosal effector memory CD4+ T cells in chronic colitis mice.2013
- Author(s)
  Takahara M, Nemoto Y, Oshima S, Matsuzawa Y, Kanai T, Okamoto R, Tsuchiya K, Nakamura T, Yamamoto K, Watanabe M.
- Journal Title
  
  Immunol Lett.
  
  Volume: 156 Issue: 1-2 Pages: 82-93
- DOI
  10.1016/j.imlet.2013.09.001
- NAID
  120005468269
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102003, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170
[Journal Article] Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury.2013
- Author(s)
  Fordham RP, Yui S, Nakamura T, Watanabe M et. al
- Journal Title
  
  Cell Stem Cell
  
  Volume: 13 Issue: 6 Pages: 734-744
- DOI
  10.1016/j.stem.2013.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PUBLICLY-24112508, KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-25670106, KAKENHI-PROJECT-25670367
[Journal Article] The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein.2013
- Author(s)
  Kano Y
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 432 Issue: 1 Pages: 175-181
- DOI
  10.1016/j.bbrc.2013.01.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23390062, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790357, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590935, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
[Journal Article] Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro2012
- Author(s)
  Mizutani T, Nakamura T, Morikawa R, Fukuda M, Mochizuki W, Yamauchi Y, NozakiK, Yui S, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, and Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419(2) Pages: 238-243
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell2012
- Author(s)
  Yui S, Nakamura T, Watanabe M, et al.
- Journal Title
  
  Nature Medicine
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro2012
- Author(s)
  Mizutani T, Nakamura T, et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419 Issue: 2 Pages: 238-243
- DOI
  10.1016/j.bbrc.2012.01.155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590803, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PUBLICLY-24112508
[Journal Article] Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro2012
- Author(s)
  Mizutani T, Nakamura T, Morikawa R, Fukuda M, Mochizuki W, Yamauchi Y, Nozaki K, Yui S, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, and Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419(2) Pages: 238-243
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+stem cell2012
- Author(s)
  Yui S, Nakamura T, Sato T, Nemoto Y, Mizutani T, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Clevers H, and Watanabe M
- Journal Title
  
  Nature Medicine
  
  Volume: 18 Issue: 4 Pages: 618-623
- DOI
  10.1038/nm.2695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590803, KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-21590806, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-23890204, KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-24790684, KAKENHI-PUBLICLY-24112508, KAKENHI-PUBLICLY-24112523
[Journal Article] The development of colitogenic CD4+ T cells is regulated by IL-7 in collaboration with natural killer cell function in a murine model of colitis2012
- Author(s)
  Yamaji O, Totsuka T
- Journal Title
  
  J Immunol
  
  Volume: 188 Issue: 6 Pages: 2524-2536
- DOI
  10.4049/jimmunol.1100371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590804, KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-21590806, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23390112, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659223, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PLANNED-23102003
[Journal Article] Gene bookmarking accelerates the kinetics of post-mitotic transcriptional activation2011
- Author(s)
  Zhao R, Nakamura T, Fu Y, Lazar Z, and Spector DL
- Journal Title
  
  Nature Cell Biology
  
  Volume: 13(11) Pages: 1295-1304
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Suppression of hathl gene expression directly regulated by hesl via notch signaling is associated with goblet celldepletion in ulcerative colitis.2011
- Author(s)
  Zheng X, Nakamura T, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] Gene bookmarking accelerates the kinetics of post-mitotic transcriptional activation2011
- Author(s)
  Zhao R, Nakamura T, Fu Y, Lazar Z, and Spector DL
- Journal Title
  
  Nature Cell Biology
  
  Volume: 13(11) Pages: 1295-1304
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Suppression of Hath1 gene expression directly regulated by Heslvia Notch signaling is associated with goblet cell depletion in ulcerative colitis2011
- Author(s)
  Zheng X, Nakamura T, et al
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17 Issue: 11 Pages: 2251-2260
- DOI
  10.1002/ibd.21611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24659359
[Journal Article] Suppression of Hath1 gene expression directly regulated by Hes1 via Notch signaling is associated with goblet cell depletion in ulcerative colitis2011
- Author(s)
  Zheng X, Tsuchiya K, Okamoto R, Iwasaki M, Kano Y, Sakamoto N, Nakamura T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17(11) Pages: 2251-2260
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Upregulated IL-7Rα expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis2011
- Author(s)
  Shinohara, T., et al
- Journal Title
  
  J.Immunol.
  
  Volume: 186 Issue: 4 Pages: 2623-2632
- DOI
  10.4049/jimmunol.1000057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23659394
[Journal Article] Longitudinal cell formation in the entire human smallintestine is correlated with the localization of Hathl and K1f4.2011
- Author(s)
  Iwasaki M, Nakamura T, Watanabe M, etal.
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Pages: 191-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] Longtudinal cell formation in the entire human small intestine is correlated with the localization of Hathl and KIM2011
- Author(s)
  Iwasaki M, Tsuchiya K, Okamoto R, Zheng X, Kano Y, Okamoto E, Okada E, Araki A, Suzuki S, Sakamoto N, Kitagaki K, Akashi T, Eishi Y, Nakamura T, Watanabe__M
- Journal Title
  
  J Gastroenterol.
  
  Volume: 46 Pages: 191-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Luminal CD4+ T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation2011
- Author(s)
  Nemoto Y, Watanabe M
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Issue: 6 Pages: 2130-2139
- DOI
  10.1053/j.gastro.2011.08.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590804, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777
[Journal Article] Suppression of Hath1 gene expression directly regulated by Hes1 via Notch signaling is associated with goblet cell depletion in ulcerative colitis2011
- Author(s)
  Zheng X, Tsuchiya K, Okamoto R, Iwasaki M, Kano Y, Sakamoto N, Nakamura T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17(11) Pages: 2251-2260
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf42011
- Author(s)
  Iwasaki M, Tsuchiya K, Okamoto R, Zheng X, Kano Y, Okamoto E, Okada E, Araki A, Suzuki S, Sakamoto N, Kitagaki K, Akashi T, Eishi Y, Nakamura T, Watanabe M
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(2) Pages: 191-201
- NAID
  10029027237
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf42011
- Author(s)
  Iwasaki M, Tsuchiya K, Okamoto R, ZhengX, Kano Y, Okamoto E, Okada E, Araki A, Suzuki S, Sakamoto N, Kitagaki K, Akashi T, Eishi Y, Nakamura T, Watanabe M
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(2) Pages: 191-202
- NAID
  10029027237
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Upretulated IL-7 receptor (alpha) expression on colitogenicmemory CD4+ T cells may participate in the developmentand persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nakamura T, Watanabe M, etal.
- Journal Title
  
  Journal of Immunology
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.2010
- Author(s)
  Akiyama J, Nakamura T, Watanabe M, et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 393 Pages: 662-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] A long nuclear retained non-coding RNA regulates synaptogenesis by modulating gene expression2010
- Author(s)
  Bernard D, Prasanth KV, Tripathi V, Colasse S, Nakamura T, Xuan Z, Zhang MQ, Sedel F, Jourdren L, Coulpier F, Triller A, Spector DL, and Bessis A
- Journal Title
  
  EMBO J
  
  Volume: 29(18) Pages: 3082-3093
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Cell culture and in-vivo analyses of plaque-derivedcytopathic hepatitis C virus mutants.2010
- Author(s)
  Mishima K, Nakamura T, Watanabe M, etal.
- Journal Title
  
  Virology.
  
  Volume: 405 Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] Nuclear organization and dynamics of 7SK RNA in regulating gene expression2010
- Author(s)
  Prasanth KV, Camiolo M, Chan G, Tripathi V, Denis L, Nakamura T, Hubner M, and Spector DL
- Journal Title
  
  Mol BiolCell
  
  Volume: 21(23) Pages: 4184-4196
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.2010
- Author(s)
  Akiyama J, Okamoto R, Nakamura T, et al
- Journal Title
  
  Biochem Biophys Res Commun. 393
  
  Pages: 662-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Nuclear organization and dynamics of 7SK RNA in regulating gene expression2010
- Author(s)
  Prasanth KV, Camiolo M, Chan G, Tripathi V, Denis L, Nakamura T, Hubner M, and Spector DL
- Journal Title
  
  Mol Biol Cell
  
  Volume: 21(23) Pages: 4184-4196
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.2010
- Author(s)
  Akiyama J, Nakamura T, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells2010
- Author(s)
  Akiyama J, Okamoto R, Iwasaki M, Zheng X, Yui S, Tsuchiya K, Nakamura T, and Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 393(4) Pages: 662-667
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells inchronic colitis.2010
- Author(s)
  Kameyama K, Nakamura T, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 40 Pages: 2423-2436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005
[Journal Article] A long nuclear retained non-coding RNA regulates synaptogenesis by modulating gene expression2010
- Author(s)
  Bernard D, Prasanth KV, Tripathi V, Colasse S, Nakamura T, Xuan Z, Zhang MQ, Sedel F, Jourdren L, Coulpier F, Triller A, Spector DL, and Bessis A
- Journal Title
  
  EMBO J
  
  Volume: 29(18) Pages: 3082-3093
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells2010
- Author(s)
  Akiyama J, Okamoto R, Iwasaki M, Zheng X, Yui S, Tsuchiya K, Nakamura T, and Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 393(4) Pages: 662-667
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia.2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 296(1)
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Signaling pathway via TNF-a/NF-kB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T, Nagano KI, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 296(4) Pages: 850-859
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia.2009
- Author(s)
  Okamoto R, Nakamura T, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 296(1) Pages: 23-35
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] Signaling pathway via TNF-a/NF-kB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T, NaganoKI, Oshima S, Nemoto Y, Yoshioka A, TotsukaT, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 296(4)
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.2009
- Author(s)
  Onizawa M, Nagaishi T, Nakamura T, et al
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
  
  Pages: 850-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia.2009
- Author(s)
  Okamoto R, Nakamura T, et al.
- Journal Title
  
  Am J Physiol GI & Liver. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590803
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.2009
- Author(s)
  Totsuka T, Kanai T, Nakamura T, et al
- Journal Title
  
  J Immunol. 182
  
  Pages: 6079-6087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805
[Journal Article] Increase of bone marrow-derived secretary lineage epithelial cells during regeneration in the human intestine.2005
- Author(s)
  Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Nakamura T, Kanai T, Hibi T, Inazawa J, Watanabe M.
- Journal Title
  
  Gastroenterology. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390229
[Journal Article] CD4+CD25^<bright> T cells in human intestinal lamina propria as regulatory cells.2004
- Author(s)
  Makita S, Kanai T, Oshima S, Uraushihara K, Totsuka T, Iiyama R, Sawada T, Nakamura T, Koganei K, Fukushima T, Watanabe M.
- Journal Title
  
  J Immunol. 173
  
  Pages: 3119-3130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390229
[Journal Article] Ectopic CD40 ligand expression on B cells triggers intestinal inflammation.2004
- Author(s)
  Kawamura T, Kanai T, Dohi T, Uraushihara K, Totsuka T, Iiyama R, Taneda C, Yamazaki M, Nakamura T, Higuchi T, Aiba Y, Tsubata T, Watanabe M.
- Journal Title
  
  J Immunol. 172
  
  Pages: 6388-6397
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390229
[Journal Article] IRF-1 and IRF-2 distinctively up-regulate gene expression and production of IL-7 in human intestinal epithelial cells2004
- Author(s)
  Oshima S, Nakamura T, et al.
- Journal Title
  
  Molecular and Cellular Biology 24
  
  Pages: 6298-6310
- Data Source
  KAKENHI-PROJECT-16590579
[Journal Article] Interferon regulatory factor 1 (IRE-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells.2004
- Author(s)
  Oshima S, Nakamura T, Namiki S, Okada E, Tsuchiya K, Okamoto R, Yamazaki M, Yokota T, Aida M, Yamaguchi Y, Kanai T, Handa H, Watanabe M.
- Journal Title
  
  Mol Cell Biol. 24
  
  Pages: 6298-6310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390229
[Patent] 腸上皮間リンパ球をインビトロで維持・増殖させる方法2015
- Inventor(s)
  中村哲也・渡辺守・野崎賢吾
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-079953
- Filing Date
  2015-04-09
- Data Source
  KAKENHI-PUBLICLY-26112705
[Patent] 大腸上皮幹細胞の単離・培養技術と、これを用いた大腸上皮移植技術2013
- Inventor(s)
  渡辺守、中村哲也
- Industrial Property Rights Holder
  渡辺守、中村哲也
- Acquisition Date
  2013-05-02
- Overseas
- Data Source
  KAKENHI-PROJECT-23659394
[Patent] 大腸上皮幹細胞の単離・培養技術とこれを用いた大腸上皮移植技術2011
- Inventor(s)
  渡辺守・中村哲也
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2011-236469
- Filing Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-22229005
[Patent] 大腸上皮幹細胞の単離・培養技術とこれを用いた大腸上皮移植技術2011
- Inventor(s)
  渡辺守,中村哲也
- Industrial Property Rights Holder
  渡辺守,中村哲也
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23659394
[Patent] 大腸上皮幹細胞の単離・培養技術とこれを用いた大腸上皮移植技術2011
- Inventor(s)
  渡辺守・中村哲也
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2011-236469
- Filing Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21590803
[Patent] 大腸上皮幹細胞の単離・培養技術とこれを用いた大腸上皮移植技術2011
- Inventor(s)
  渡辺守・中村哲也
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21590805
[Patent] 大腸上皮幹細胞の単離・培養技術とこれを用いた大腸上皮移植技術2011
- Inventor(s)
  渡辺守・中村哲也
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] オルガノイド移植による腸管不全治療の臨床応用に向けた新規キレート剤の安全性と移植技術利用可能性の検証2023
- Author(s)
  松本有加、須田一人、山高篤行、中村哲也
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K24397
[Presentation] オルガノイド移植による腸管不全治療の臨床応用に向けた新規キレート剤の安全性と移植技術利用可能性の検証2023
- Author(s)
  松本有加、須田一人、山高篤行、中村哲也
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K19541
[Presentation] Mechanisms of bladder urothelial differentiation analyzed using the organoids culture2022
- Author(s)
  須田一人、松本有加、越智崇徳、古賀寛之、山髙篤行、中村哲也
- Organizer
  第122回日本外科学会定期学術集会。2022年
- Data Source
  KAKENHI-PROJECT-20K21637
[Presentation] 無血清培地による切除腸組織由来小児小腸オルガノイド培養方法の確立2021
- Author(s)
  松本有加、須田一人、三上敬文、古賀寛之、服部　信孝、岡崎任晴、山髙篤行、中村哲也
- Organizer
  第37回日本小児外科学会秋季シンポジウム
- Data Source
  KAKENHI-PROJECT-19K09083
[Presentation] 膀胱上皮オルガノイド培養における増殖・分化機構の検討2021
- Author(s)
  須田一人、松本有加、越智崇徳、古賀寛之、山髙篤行、中村哲也
- Organizer
  第37回日本小児外科学会秋季シンポジウム。2021年
- Data Source
  KAKENHI-PROJECT-20K21637
[Presentation] ANALYSIS OF THE BLADDER EPITHELIUM DIFFERENTIATION MECHANISM USING THE ORGANOID CULTURE2021
- Author(s)
  Kazuto Suda, Yuka Matsumoto, Takanori Ochi, Hiroyuki Koga, Atsuyuki Yamataka, Tetsuya Nakamura
- Organizer
  22nd European Paediatric Surgeons' Association Congress. 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21637
[Presentation] 無血清・既知組成培地を用いた外科切除腸組織からの小児小腸オルガノイド培養2021
- Author(s)
  松本有加、須田一人、三上敬文、古賀寛之、服部　信孝、岡崎任晴、山髙篤行、中村哲也
- Organizer
  第58回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09083
[Presentation] biotubeと小腸上皮オルガノイドを用いた小腸再生の研究2021
- Author(s)
  鈴木啓介，古村　眞，古村浩子，鈴木　完，藤代　準，松本有加，中村哲也，中川泰秀
- Organizer
  第58回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09067
[Presentation] オルガノイド培養を用いた膀胱上皮分化機構の解析2021
- Author(s)
  須田一人、松本有加、越智崇徳、古賀寛之、山髙篤行、中村哲也
- Organizer
  第58回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21637
[Presentation] 小腸再生を目指した小腸上皮オルガノイドのbiotubeへの接着の研究2020
- Author(s)
  鈴木啓介、古村眞、古村浩子、鈴木完、藤代準、松本有加、中村哲也、中山泰秀
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09067
[Presentation] オルガノイド移植による大腸上皮置換術の確立と移植上皮の網羅的遺伝子発現解析2020
- Author(s)
  松本有加、平田潤、東貴大、野田幸子、服部信孝、岡田随像、山高篤行、中村哲也
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] 小腸再生を目指した小腸上皮オルガノイドのbiotubeへの接着の研究2020
- Author(s)
  鈴木啓介、古村眞、古村浩子、鈴木完、藤代準、松本有加、中村哲也、中山泰秀
- Organizer
  第19回日本再生医療学会総会(2020年5月18日～ 5月29日, Web開催)
- Data Source
  KAKENHI-PROJECT-19K09067
[Presentation] 小腸再生を目指した小腸上皮オルガノイドのbiotubeへの接着の研究2020
- Author(s)
  鈴木啓介、古村眞、古村浩子、鈴木完、藤代準、松本有加、中村哲也、中山泰秀
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] 小腸再生を目指した小腸上皮オルガノイドのbiotubeへの接着の研究2020
- Author(s)
  鈴木啓介、古村眞、古村浩子、鈴木完、藤代準、松本有加、中村哲也、中山泰秀
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] 小腸オルガノイド移植による大腸上皮置換技術を用いた小腸機能不全治療の開発2020
- Author(s)
  松本有加、山高篤行、中村哲也
- Organizer
  第57回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] 大腸への小腸上皮オルガノイド移植による腸管不全治療技術開発2020
- Author(s)
  松本有加、野田幸子、渡辺守、服部信孝、山高篤行、中村哲也
- Organizer
  第120回日本外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] オルガノイド―小児外科分野における可能性―2020
- Author(s)
  中村哲也
- Organizer
  第57回日本小児外科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] Synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients leads to up-regulation of UBD, a ubiquitin-like protein.2019
- Author(s)
  Kawamoto A, Nagata S, Anzai S, Takahashi J, Kawai M, Hama M, Nogawa D, Yamamoto K, Kuno R, Suzuki K, Shimizu H, Hiraguri Y, Yui S, Oshima S, Tsuchiya K, Nakamura T, Ohtsuka K, Kitagawa M, Okamoto R, Watanabe M
- Organizer
  ECCO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] オルガノイド移植による未来の腸再生医療2019
- Author(s)
  中村哲也
- Organizer
  第31回小腸移植研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19674
[Presentation] オルガノイド移植による未来の腸再生医療2019
- Author(s)
  中村哲也
- Organizer
  第31回小腸移植研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02867
[Presentation] TP53 mutation in human colonic organoids acquires resistance to in vitro long-term inflammation.2019
- Author(s)
  Tsuchiya K, Watanabe S, Shirasaki T, Nishimura R, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  ECCO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] UC-related and segment-specific properties of patientderived colonic organoids.2019
- Author(s)
  Suzuki K, Shimizu H, Kawai M, Takahashi J, Anzai S, Kawamoto A, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
- Organizer
  ECCO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Fetalization of colonic epithelium medicated by YAP/TAZ links ECM remodeling to tissue regeneration.2018
- Author(s)
  Yui S, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
- Organizer
  GI Research Academy2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Development of a new mouse model of short bowel syndrome that may allow for the assessment of therapeutic efficacy of heterotopic transplantation of small intestinal organoids.2018
- Author(s)
  Matsumoto Y, Watanabe M, Nakamura T
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Identification of lesion-specific epithelial function of ulcerative colitis by comparing colonic organoids from lesion and non-lesion parts of same patients.2018
- Author(s)
  Shirasaki T, Tsuchiya K, Nishimura R, Watanabe S, Hibiya S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
- Organizer
  DDW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Lesion-specific gene expression in the Epithelial cells of Crohn’s disease by comparing Small intestinal organoids from active and inactive Lesion in the same patient.2018
- Author(s)
  Hibiya S, Tsuchiya K, Nishimura R, Shirasaki T, Watanabe S, Katsukura N, Okamoto R, Nakamura T, Watanabe M
- Organizer
  UEGW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] The identification of lesion-specific gene expression in intestinal epithelial cells of Ulcerative Colitis by comparing colonic organoids from lesion and non-lesion parts of same patients.2018
- Author(s)
  Nishimura R, Tsuchiya K, Shirasaki T, Watanabe S, Hibiya S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  The 13th Congress of ECCO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Tp53 mutation enhances cell proliferation and stemness in human colon epithelial organoids and promotes a resistance against long-term inflammation.2018
- Author(s)
  Watanabe S, Tsuchiya K, Shirasaki T, Hibiya S, Nishimura S, Katsukura N, Oshima S, Okamoto R, Tetsuya N, Watanabe M
- Organizer
  UEGW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Crohn’s disease patient-derived small intestinal organoids reveal disease-status related modification of stem cell properties. 52018
- Author(s)
  Suzuki K, Murano T, Hiraguri Y, Takahashi J, Shimizu H,Anzai S, Kuwabara K, Kawamoto A, Ishibashi F, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] 腸オルガノイドによる再生医療を目指した新規小腸機能不全マウスモデルの開発と移植方法の検討2018
- Author(s)
  松本有加、渡辺守、中村哲也
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K19674
[Presentation] Mouse colonic secretory cells de-differentiate into intestinal stem cells and promote mucosal repair through activation of NF-KB signaling.2018
- Author(s)
  Ishibashi F, Shimizu H, Kawamoto A, Suzuki K, Anzai S, Kuwabara K, Takahashi J, Nagata S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R
- Organizer
  ISSCR2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Ectopic expression of reg3a in the mice distal Colon is mediated by interactions between notch and Il-22 signaling pathways, and promotes tissue repair By the augmentation of EGFR signaling.2018
- Author(s)
  Ishibashi F, Kuwabara K, Kawamoto A, Anzai S, Takahashi J, Nagata S, Shimizu H, Yui S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R
- Organizer
  UEGW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Crohn’s disease patient-derived small intestinal organoids reveal diseasestatus related modification of stem cell properties.2018
- Author(s)
  Suzuki K, Takahashi J, Hiraguri Y, Yui S, Shimizu H, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
- Organizer
  5th TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Human colonic organoid treated with inflammatory factors might mimic the pathophysiology of epithelial cells in ulcerative colitis.2018
- Author(s)
  Hibiya S, Tsuchiya K, Watanabe S, Nishimura R, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  DDW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Long-lived secretory cells residing in the mouse proximal colon serve as reserve stem cells under DNA damage-induced mucosal injury.2018
- Author(s)
  Kuwabara K, Ishibashi F, Kawamoto A, Anzai S, Takahashi J, Nagata S, Shimizu H, Yui S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R
- Organizer
  UEGW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Single-cell level analysis of organoids derived from CD patients reveals disease-status related modifications of small intestinal stem cells.2018
- Author(s)
  Suzuki K, Kuwabara K, Takahashi J, Anzai S, Kuno R, Kawamoto A, Ishibashi F, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
- Organizer
  DDW 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Lineage tracing reveals contribution of Atoh1+ cell-derived stem cells in the homeostasis, repair, and carcinogenesis of the intestinal epithelium2017
- Author(s)
  Ishibashi F, Shimizu H, Nakata T, Fujii S, Suzuki K, Kawamoto A, Anzai S, Kuno R, Nagata S, Ito G, Murano T, Oshima S, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M
- Organizer
  DDW2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] オルガノイド移植による腸再生医療2017
- Author(s)
  中村哲也
- Organizer
  第33回日本小児外科学会・秋季シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19674
[Presentation] Intestinal Stem Cell Transplantation2017
- Author(s)
  中村哲也
- Organizer
  第54回日本消化器免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19674
[Presentation] Reprogrammed Atoh1+ intestinal epithelial cells contribute to regenerate damaged colonic mucosa in DSS-induced colitis.2017
- Author(s)
  Ishibashi F, Shimizu H, Nakata T, Fujii S, Suzuki K, Kawamoto A, Anzai S, Kuno R, Nagata S, Ito G, Murano T, Oshima S, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M
- Organizer
  UEGW2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Construction of in vitro model of ulcerative colitis using mouse primary colonic organoid2016
- Author(s)
  Hibiya S, Tsuchiya K, Watanabe S, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  UEGW2016
- Place of Presentation
  ウィーン（オーストリア）
- Year and Date
  2016-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Single-Cell Level Analysis Reveals Heterogeneous Expression of Stem-Cell Specific Genes in Human Small Intestinal Organoids2016
- Author(s)
  Suzuki K, Fujii S, Kawamoto A, Ishibashi F, Nakata T, Ito G, Shimizu H, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
- Organizer
  DDW2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] ATOH1 Protein Stabilization in Tumor Acquires the Morphological Change to Signet Ring Cell Carcinoma With Cancer Stem Cell Enrichment in Colon Cancer.2016
- Author(s)
  Tsuchiya K, Hibiya S, Fukushima K, Shirasaki T, Okamoto R, Nakamura T, Watanabe M
- Organizer
  DDW2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] In Vitro organoid model reveals PGF2 as a Robust Mediator of chloride & water secretion bt human intestinal epithelial cells.2016
- Author(s)
  Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Nakata T, Ito G, Shimizu H, Mizutani T, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M
- Organizer
  DDW2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] 上皮幹細胞移植による腸再生2016
- Author(s)
  中村哲也
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] OLFM4 and UBD are up-regulated in the inflamed intestinal epithelia of IBD patients by synergy of Notch signaling and TNF-α2016
- Author(s)
  Kawamoto A, Ito G, Nakata T, Fujii S, Suzuki K, Ishibashi F, Shimizu H, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M
- Organizer
  AOCC 2016
- Place of Presentation
  京都国際会議場（京都府・京都市)
- Year and Date
  2016-07-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Retinol stimulates proliferation of epithelial stem cells of the proximal colon through a retinoic acid-independent mechanism.2016
- Author(s)
  Matsumoto T, Mochizuki W, Nibe Y, Akiyama S, Matsumoto Y, Nozaki K, Mizutani T, Oshima S, Watanabe M, Nakamura T
- Organizer
  DDW2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Mouse colonic organoid acquires wnt-independent survival property after long-term inflammation2016
- Author(s)
  Hibiya S, Tsuchiya K, Shirasaki T, Fukushima K, Oshima S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  AOCC 2016
- Place of Presentation
  京都国際会議場（京都府・京都市)
- Year and Date
  2016-07-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Stimulation with the ligands of toll like receptors in primary human organoids2016
- Author(s)
  Shirasaki T, Tsuchiya K, Hibiya S, Nishimura R, Watanabe S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  AOCC 2016
- Place of Presentation
  京都国際会議場（京都府・京都市）
- Year and Date
  2016-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Atoh1 protein stabilization in colon tumor acquires the　morphological change to signet ring cell carcinoma with cancer stem cell　enrichment.2016
- Author(s)
  Tsuchiya K, Hibiya S, Fukushima K, Shirasaki T, Oshima S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  APDW2016
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Jagged1 is Indispensable for the Maintenance of Tumor Stem Cell Niche in APC-Deficient Intestinal Adenomas2016
- Author(s)
  Nakata T, Ito G, Shimizu H, Fujii S, Suzuki K, Ishibashi F, Kawamoto A, Tsuchiya K, Nakamura T, Hozumi K, Okamoto R, Watanabe M
- Organizer
  DDW2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Construction of In Vitro Model for Inflammatory Bowel Disease Using Primary Colonic Organoid2016
- Author(s)
  Hibiya S, Tsuchiya K, Shirasaki T, Fukushima K, Oshima S, Okamoto R, Nakamura T, Watanabe M
- Organizer
  DDW2016
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Contiuous stimulation with cytokines leads to irreversible activation of NF-kB signaling in colonic epithelial cells by organoid culture.2015
- Author(s)
  Shuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, M. Watanabe
- Organizer
  UEGW2015.
- Place of Presentation
  Barcelona（Spain）
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Contiuous stimulation with cytokines leads to irreversible activation of NF-γb signaling in colonic epithelial cells by organoid culture.2015
- Author(s)
  Shuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima ,Ryuichi Okamoto, Tetsuya Nakamura,Mamoru Watanabe
- Organizer
  UEGW2015
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Distinct Role of Notch Ligands, DLL1 and Dll4, in Normal and in Tumor Intestinal Epithelium.2015
- Author(s)
  Toru Nakata, Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.
- Organizer
  DDW 2015
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] 上皮幹細胞移植による大腸・小腸組織再生2015
- Author(s)
  中村哲也
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2015-04-24
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] Establishment of a 3D cell culture-based screening platform to identify natural products that can regulate transepithelial water transport of the human gastrointestinal tract.2015
- Author(s)
  Satoru Fujii, Ryuichi Okamoto, Toru Nakata, Kohei Suzuki, Fumiaki Ishibashi, Ami Kawamoto,Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  Pacifichem2015
- Place of Presentation
  ハワイ（米国）
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.2015
- Author(s)
  Kohei Suzuki, Satoru Fujii, Toru Nakata, Ami Kawamoto, Fumiaki Ishibashi, Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya, Kazuo Otsuka,Tetsuya Nakamura, Ryuichi Okamoto, M. Watanabe
- Organizer
  DDW 2015
- Place of Presentation
  Washington,D.C.（U.S.A.）
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Atoh1 Protein Expression by TNF-a and the Acquisition of Malignant Potential in Colitis- Associated Colorectal Cancer.2015
- Author(s)
  Keita Fukushima, Kiichiro Tsuchiya, Shuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Yoshihito Kano, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  DDW 2015
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Establishment of a 3D cell culture-based screening platform to identify natural products that can regulate transepithelial water transport of the human gastrointestinal tract.2015
- Author(s)
  Fujii Satoru, Okamoto Ryuichi, Nakata Toru, Suzuki Kohei, Ishibashi Fumiaki, Kawamoto Ami, Segawa Sayaka-Ohashi, Mizutani Tomohiro, Tsuchiya Kiichiro, Nakamura Tetsuya, Mamoru Watanabe
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii（U.S.A.）
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] Atoh1 protein stabilized by TNF-α acquires enhanced malignant potential in colitis-associated colorectal cancer.2015
- Author(s)
  Tomoaki Shirasaki, Keita Fukushima, Kiichiro Tsuchiya, Shuuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  AOCC2015
- Place of Presentation
  北京（中国）
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] A novel fluorescent labelling system into small intestinal organoid reveals independent long-lived intestinal stem cells in a crypt.2015
- Author(s)
  Horita N,Tsuchiya K,Hayashi R,Fukushima K,Hibiya S,Fukuda M,Mizutani T,Okamoto R,Nakamura T and Watanabe M.
- Organizer
  AOCC2015
- Place of Presentation
  北京（中国）
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 培養細胞移植実験を利用する腸管上皮幹細胞解析2015
- Author(s)
  中村哲也
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] Live Imaging Analysis of Intraepithelial Lymphocytes (IELs) Co-cultured with Intestinal Epithelial Organoids2015
- Author(s)
  Nozaki K, Mochizuki W, Matsumoto Y, Matsumoto T, Fukuda M, Mizutani T, Watanabe M, Nakamura T
- Organizer
  Cold Spring Harbor Meeting “Fundamental Immunology and Its Therapeutic Potential”
- Place of Presentation
  Cold Spring Harbor, NY（USA）
- Year and Date
  2015-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] Continuous Stimulation With Cytokines Leads to Irreversible Accumulation of NF-kB Signaling in Colonic Epithelial Cells.2015
- Author(s)
  Shuji Hibiya, Kiichiro Tsuchiya, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, M. Watanabe
- Organizer
  DDW 2015
- Place of Presentation
  Washington,D.C.（U.S.A.）
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] A novel fluorescent labelling system into small intestinal organoid reveals independent long-lived intestinal stem cells in a crypt.2015
- Author(s)
  Nobuyuki Horita, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Masayoshi Fukuda, Tomohiro Mizutani, Ryuichi Okamoto, Testuya Nakamura and M. Watanabe
- Organizer
  AOCC2015
- Place of Presentation
  北京（China）
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221307
[Presentation] 培養細胞移植実験を利用する腸管上皮幹細胞解析2015
- Author(s)
  中村哲也
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] A novel fluorescent labelling system into small intestinal organoid reveals independent long-lived intestinal stem cells in a crypt.2015
- Author(s)
  Horita N,Tsuchiya K,Hayashi R,Fukushima K,Hibiya S,Fukuda M,Mizutani T,Okamoto R,Nakamura T and Watanabe M.
- Organizer
  AOCC2015
- Place of Presentation
  北京（中国）
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Epithelial regeneration by transplantation of intestinal epithelial stem cells2015
- Author(s)
  Tetsuya Nakamura
- Organizer
  2nd International Meeting for Epithelial Tubulology
- Place of Presentation
  北海道大学医学部学友会館（北海道札幌市）
- Year and Date
  2015-08-22
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] TNF-α stabilizes atoh1 protein in colitis-associated colorectal cancer resulting in enhanced malignant potential.2015
- Author(s)
  Tomoaki Shirasaki, Keita Fukushima, Kiichiro Tsuchiya, Shuuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  UEGW2015
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Establishment of a 3D cell culture-based screening platform to identify natural products that can regulate transepithelial water transport of the human gastrointestinal tract.2015
- Author(s)
  Satoru Fujii, Ryuichi Okamoto, Toru Nakata, Kohei Suzuki, Fumiaki Ishibashi, Ami Kawamoto,Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  Pacifichem2015
- Place of Presentation
  ハワイ（米国）
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.2015
- Author(s)
  Kohei Suzuki,Satoru Fujii,Toru Nakata,Ami Kawamoto,Fumiaki Ishibashi,Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya,Kazuo Otsuka,Tetsuya Nakamura,Ryuichi Okamoto,Mamoru Watanabe.
- Organizer
  AOCC2015
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Notch Ligands DLL1 and Dll4 Are Expressed by Distinct Population of Epithelial Cells in the Mice Intestine.2015
- Author(s)
  Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Toru Nakata, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.
- Organizer
  DDW 2015
- Place of Presentation
  ワシントン；米国
- Year and Date
  2015-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] 大腸上皮細胞特異的なTNFシグナルによるIBD合併大腸癌発生機構の解析2015
- Author(s)
  永石宇司、渡部太郎、鈴木雅博、Jose Nisha、東海有沙、細谷明徳、鬼沢道夫、中村哲也、渡辺守
- Organizer
  第11回日本消化管学会総会学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] Notch Ligands DLL1 and Dll4 Are Expressed by Distinct Population of Epithelial Cells in the Mice Intestine.2015
- Author(s)
  Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Toru Nakata, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.
- Organizer
  DDW 2015
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2015-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] シンポジウム「内胚葉系臓器の再生医療と幹細胞生物学」培養細胞移植実験を利用する腸管上皮幹細胞解析2015
- Author(s)
  中村哲也
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] Live imaging analysis of intraepithelial lymphocytes (IELs) co-cultured with intestinal epithelial organoids.2015
- Author(s)
  Nozaki K, Mochizuki W, Matsumoto Y, Matsumoto T, Fukuda M, Mizutani T, Watanabe M, Nakamura T
- Organizer
  Cold Spring Harbor Meeting "Fundamental Immunology and Its Therapeutic Applications"
- Place of Presentation
  ニューヨーク（米国）
- Year and Date
  2015-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Continuous Stimulation With Cytokines Leads to Irreversible Accumulation of NF-kB Signaling in Colonic Epithelial Cells.2015
- Author(s)
  Shuji Hibiya, Kiichiro Tsuchiya, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  DDW 2015
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Atoh1 protein stabilized by TNF-α acquires enhanced malignant potential in colitis-associated colorectal cancer.2015
- Author(s)
  Tomoaki Shirasaki, Keita Fukushima, Kiichiro Tsuchiya, Shuuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  AOCC2015
- Place of Presentation
  北京（中国）
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Distinct Role of Notch Ligands, DLL1 and Dll4, in Normal and in Tumor Intestinal Epithelium.2015
- Author(s)
  Toru Nakata, Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.
- Organizer
  DDW 2015
- Place of Presentation
  ワシントン（米国）
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 上皮幹細胞移植による大腸・小腸再生医療の可能性2015
- Author(s)
  中村哲也
- Organizer
  千里ライフサイエンスセミナー
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-05-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] 培養細胞移植実験を利用する腸管上皮幹細胞解析2015
- Author(s)
  中村哲也
- Organizer
  第14回日本再生医療学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.2015
- Author(s)
  Kohei Suzuki,Satoru Fujii,Toru Nakata,Ami Kawamoto,Fumiaki Ishibashi,Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya,Kazuo Otsuka,Tetsuya Nakamura,Ryuichi Okamoto,Mamoru Watanabe.
- Organizer
  AOCC2015
- Place of Presentation
  北京（中国）
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] TNF-α stabilizes atoh1 protein in colitis-associated colorectal cancer resulting in enhanced malignant potential.2015
- Author(s)
  Tomoaki Shirasaki, Keita Fukushima, Kiichiro Tsuchiya, Shuuji Hibiya, Ryohei Hayashi, Nobukatsu Horita, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  UEGW2015
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Successful Engraftment of Cultured Small Intestinal Epithelial Stem Cells onto Damaged Colonic Mucosa by Heterotopic Transplantation2014
- Author(s)
  Fukuda M, Mizutani T, Mochizuki W, Matsumoto T, Nozaki K, Ichinose S, Watanabe M, Nakamura T
- Organizer
  ISSCR (International Society for Stem Cell Research) 12th Annual Meeting
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養腸管上皮細胞移植における幹細胞の挙動2014
- Author(s)
  中村哲也、渡辺守
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム、東京
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] 培養細胞移植マウスモデルを用いる腸管上皮幹細胞解析2014
- Author(s)
  中村哲也
- Organizer
  第8回 In Vivo実験医学シンポジウム
- Place of Presentation
  学士会館、東京
- Year and Date
  2014-11-13
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養腸管上皮幹細胞移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] 培養上皮幹細胞を用いた消化管再生医療の可能性2014
- Author(s)
  中村哲也
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2014-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] 培養消化管上皮幹細胞の移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館、京都
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] 培養・移植技術を利用する正常腸上皮幹細胞解析2014
- Author(s)
  中村哲也
- Organizer
  In vitro培養系を用いた上皮管腔構造の解析検討会
- Place of Presentation
  浜松町センタービル、東京
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] 培養腸管上皮細胞移植における幹細胞の挙動2014
- Author(s)
  中村哲也、渡辺守
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム、東京
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] 培養腸管上皮幹細胞移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] Notch signaling and TNF-α synergistically up-regulates expression of OLFM4 in human intestinal epithelial cells.2014
- Author(s)
  Go Ito, Ryuichi Okamoto, Tasturo Murano, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe .
- Organizer
  第8回Japan-US Collabaration Conference in Gastroenterology
- Place of Presentation
  Intercontinental TOKYO BAY (東京都港区海岸1-16-2)
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] 培養消化管上皮幹細胞の移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館、京都
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養腸管上皮幹細胞移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養・移植技術を利用する正常腸上皮幹細胞解析2014
- Author(s)
  中村哲也
- Organizer
  In vitro培養系を用いた上皮管腔構造の解析検討会
- Place of Presentation
  浜松町センタービル、東京
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Successful Engraftment of Cultured Small Intestinal Epithelial Stem Cells onto Damaged Colonic Mucosa by Heterotopic Transplantation2014
- Author(s)
  Fukuda M, Mizutani T, Mochizuki W, Matsumoto T, Nozaki K, Ichinose S, Watanabe M, Nakamura T
- Organizer
  ISSCR (International Society for Stem Cell Research) 12th Annual Meeting
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] Notch signaling and TNF-α synergistically promotes intracellular protein expression of OLFM4 in human intestinal epithelial cells.2014
- Author(s)
  Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  The 2nd Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 培養腸管上皮幹細胞移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] 培養・移植技術を利用する正常腸上皮幹細胞解析2014
- Author(s)
  中村哲也
- Organizer
  In vitro培養系を用いた上皮管腔構造の解析検討会
- Place of Presentation
  浜松町センタービル、東京
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] Notch signaling and TNF-α synergistically up-regulates expression of OLFM4 in human intestinal epithelial cells.2014
- Author(s)
  Go Ito, Ryuichi Okamoto, Tasturo Murano, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  第8回Japan-US Collabaration Conference in Gastroenterology
- Place of Presentation
  Intercontinental TOKYO BAY (東京都港区海岸1-16-2)
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 培養細胞移植マウスモデルを用いる腸管上皮幹細胞解析2014
- Author(s)
  中村哲也
- Organizer
  第8回 In Vivo実験医学シンポジウム
- Place of Presentation
  学士会館、東京
- Year and Date
  2014-11-13
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] 消化管幹細胞研究の新たな展開培養腸管上皮細胞移植における幹細胞の挙動2014
- Author(s)
  中村哲也、渡辺守
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] Successful Engraftment of Cultured Small Intestinal Epithelial Stem Cells onto Damaged Colonic Mucosa by Heterotopic Transplantation2014
- Author(s)
  Mizutani T, Fukuda M, Mochizuki W, Matsumoto T, Nozaki K, Ichinose S, Watanabe M, Nakamura T タイトル
- Organizer
  Digestive Disease Week 2014
- Place of Presentation
  シカゴ、米国
- Year and Date
  2014-05-03
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] 培養上皮幹細胞を用いた消化管再生医療の可能性2014
- Author(s)
  中村哲也
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2014-04-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] Successful Engraftment of Cultured Small Intestinal Epithelial Stem Cells onto Damaged Colonic Mucosa by Heterotopic Transplantation2014
- Author(s)
  Mizutani T, Fukuda M, Mochizuki W, Matsumoto T, Nozaki K, Ichinose S, Watanabe M, Nakamura T
- Organizer
  Digestive Disease Week 2014
- Place of Presentation
  シカゴ、米国
- Year and Date
  2014-05-03
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養消化管上皮幹細胞の移植と組織再生2014
- Author(s)
  中村哲也
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館、京都
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] Notch signaling and TNF-α synergistically promotes intracellular protein expression of OLFM4 in human intestinal epithelial cells.2014
- Author(s)
  Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  The 2nd Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Distinct Expression Patterns of Notch Ligands, DLL1 and DLL4, in Normal and Inflamed Mice Intestine.2014
- Author(s)
  Hiromichi Shimizu, Ryuichi Okamoto, Go Ito, Satoru Fujii, Toru Nakata, Kohei Suzuki, Tatsuro Murano, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe.
- Organizer
  The 2nd Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Successful Engraftment of Cultured Small Intestinal Epithelial Stem Cells onto Damaged Colonic Mucosa by Heterotopic Transplantation2014
- Author(s)
  Fukuda M, Mizutani T, Mochizuki W, Matsumoto T, Nozaki K, Ichinose S, Watanabe M, Nakamura T
- Organizer
  ISSCR (International Society for Stem Cell Research) 12th Annual Meeting
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] 培養細胞移植マウスモデルを用いる腸管上皮幹細胞解析2014
- Author(s)
  中村哲也
- Organizer
  第8回 In Vivo実験医学シンポジウム
- Place of Presentation
  学士会館、東京
- Year and Date
  2014-11-13
- Invited
- Data Source
  KAKENHI-PUBLICLY-26112705
[Presentation] 培養上皮幹細胞を用いた消化管再生医療の可能性2014
- Author(s)
  中村哲也
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡）
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養腸管上皮細胞移植における幹細胞の挙動2014
- Author(s)
  中村哲也
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Notch Signaling and TNF-alpha synergistically promotes intracellular protein accumulation of olfm4 in the inflamed mucosa of ulcerative colitis.2014
- Author(s)
  Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  UEGW2014
- Place of Presentation
  Vienna (Austria)
- Year and Date
  2014-10-21
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Successful Engraftment of Cultured Small Intestinal Epithelial Stem Cells onto Damaged Colonic Mucosa by Heterotopic Transplantation2014
- Author(s)
  Mizutani T, Fukuda M, Mochizuki W, Matsumoto T, Nozaki K, Ichinose S, Watanabe M, Nakamura T
- Organizer
  Digestive Disease Week 2014
- Place of Presentation
  シカゴ、米国
- Year and Date
  2014-05-03
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] Distinct Expression Patterns of Notch Ligands, DLL1 and DLL4, in Normal and Inflamed Mice Intestine2014
- Author(s)
  Hiromichi Shimizu, Ryuichi Okamoto, Go Ito, Satoru Fujii, Toru Nakata, Kohei Suzuki, Tatsuro Murano, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe
- Organizer
  The 2nd Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 培養腸管上皮細胞移植における幹細胞の挙動2014
- Author(s)
  中村哲也、渡辺守
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム、東京
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Notch Signaling and TNF-alpha synergistically promotes intracellular protein accumulation of olfm4 in the inflamed mucosa of ulcerative colitis.2014
- Author(s)
  Go Ito, Ryuichi Okamoto, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Kohei Suzuki, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe.
- Organizer
  UEGW2014
- Place of Presentation
  Vienna (Austria)
- Year and Date
  2014-10-21
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] 培養上皮幹細胞を用いた消化管再生医療の可能性2014
- Author(s)
  中村哲也
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2014-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Epithelial regeneration by cultured colonic cells expanded from a single adult Lgr5+ stem cell2013
- Author(s)
  Nakamura Tetsuya
- Organizer
  1st International Meeting for Epithelial Tubulology
- Place of Presentation
  Hokkaido University（北海道）
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 組織幹細胞を用いた消化管上皮再生2013
- Author(s)
  中村哲也
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] 組織幹細胞を用いた消化管上皮再生2013
- Author(s)
  中村哲也
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] 組織幹細胞を用いた消化管上皮再生2013
- Author(s)
  中村哲也
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養大腸上皮細胞による消化管再生へのアプローチ2013
- Author(s)
  中村哲也
- Organizer
  3. 第99回日本消化器病学会総会シンポジウム
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Epithelial regeneration by cultured colonic cells expanded from a single adult Lgr5+ stem cell2013
- Author(s)
  Nakamura Tetsuya
- Organizer
  1st International Meeting for Epithelial Tubulology
- Place of Presentation
  Hokkaido University（北海道）
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] 培養上皮幹細胞による消化管再生医療の可能性2013
- Author(s)
  中村哲也
- Organizer
  第12回日本再生医療学会総会シンポジウム「器官臓器再生」
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] 培養大腸上皮細胞による消化管再生へのアプローチ2013
- Author(s)
  中村哲也、渡辺守
- Organizer
  第99回日本消化器病学会総会シンポジウム
- Place of Presentation
  鹿児島
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養上皮幹細胞による消化管再生医療の可能性2013
- Author(s)
  中村哲也
- Organizer
  第12回日本再生医療学会総会シンポジウム「器官臓器再生」
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Epithelial regeneration by cultured colonic cells expanded from a single adult Lgr5+ stem cell2013
- Author(s)
  Nakamura Tetsuya
- Organizer
  1st International Meeting for Epithelial Tubulology
- Place of Presentation
  Hokkaido University（北海道）
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] Epithelial regeneration by cultured colonic cells expanded from a single adult Lgr5+ stem cell2012
- Author(s)
  Nakamura T, Watanabe M
- Organizer
  The 6th Korea-Japan IBD Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-22229005
[Presentation] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell.2012
- Author(s)
  Tetsuya Nakamura
- Organizer
  James W. Freston Single Topic Conference: Gastrointestinal Stem Cell Biology and Pathobiology.
- Place of Presentation
  Chicago, USA
- Year and Date
  2012-08-27
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Epithelial regeneration by cultured colonic cells expanded from a single adult LGR5+stem cell2012
- Author(s)
  Tetsuya Nakamura(Invited Speaker)
- Organizer
  The 6th Korea-JapanIBD Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Successful engraftment of colonic epithelium expanded in vitro from a single adult Lgr5+stem cell.2012
- Author(s)
  Nakamura T (Invited Speaker)
- Organizer
  9th International Diabetes Federation Western Pacific Region Congress. 4th Scientific Meeting of the Asian Association for the Study of Diabetes.
- Place of Presentation
  Kyoto
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+stem cell.2012
- Author(s)
  Nakamura T
- Organizer
  James W. Freston Single Topic Conference : Gastrointestinal Stem Cell Biology and Pathobiology.
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] The acquisition of cancer stemness in colon cancer by the Atoh1 protein stabilization.2012
- Author(s)
  Kano Y, Okamoto R, Nakamura T, Watanabe M et al
- Organizer
  ISSCR2012
- Place of Presentation
  横浜
- Year and Date
  2012-06-14
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Epithelial regeneration by cultured colonic cells expanded from asingle adult Lgr5+ stem cell2012
- Author(s)
  Tetsuya Nakamura
- Organizer
  The 6th Korea-Japan IBD Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+ stem cells maintained and expanded in vitro2012
- Author(s)
  Yui S, Nakamura T, Nemoto Y, Mizutani T, Fukuda M, Nozaki K, Yamauchi Y, Mochiduki W, Zheng X, Nagaishi T, Okamoto R, Tsuchiya K, Watanabe M
- Organizer
  第10回幹細胞シンポジウム
- Place of Presentation
  淡路島
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-23659394
[Presentation] The acquisition of cancer stemness in colon cancer by the Atoh1 protein stabilization.2012
- Author(s)
  Kano Y, Okamoto R, Nakamura T, Watanabe M　et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Real-time analysis of p-glycoprotein-mediated drug transport across primary intestinal epitherial cells three-dimensionally cultured in vitro.2012
- Author(s)
  Mizutani T, Nakamura T, Okamoto R, Watanabe M　et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Colitogenic effector memory CD4+ T cells develop TH1/TH17 mediated interstitial pneumonia independent to intestinal bacterial antigens.2012
- Author(s)
  Nemoto Y, Okamoto R, Nakamura T, Watanabe M et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 体外培養した腸管上皮幹細胞による大腸上皮傷害の修復2012
- Author(s)
  中村哲也
- Organizer
  日本臨床免疫学会総会 6学会合同特別シンポジウム
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+Stemcells maintained and expaneled in vitro.2012
- Author(s)
  油井史郎、中村哲也, 他
- Organizer
  第10回幹細胞シンポジウム
- Place of Presentation
  淡路
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Flagellin response via TLR5 on basolateral membrane of primary intestinal epithelial cells is regulated by Notch signaling.2012
- Author(s)
  Tsuchiya K, Okamoto R, Nakamura T, Watanabe M et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+ stem cells maintained and expanded in vitro.2012
- Author(s)
  Yui S, Nakamura T, Okamoto R, Watanabe M et al
- Organizer
  第10回幹細胞シンポジウム
- Place of Presentation
  淡路島
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Epithelial regeneration by cultured colonic cells expanded from a single adult Lgr5+ stem cell2012
- Author(s)
  Nakamura T
- Organizer
  The 6th Korea-Japan IBD Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+stem cell.2012
- Author(s)
  Nakamura T
- Organizer
  ISSCR (International Society for Stem Cell Research)10th annual meeting.
- Place of Presentation
  Yokohama
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Epithelial regeneration by cultured coloniccells expanded from a single adult LGR5+stem cell2012
- Author(s)
  Tetsuya Nakamura
- Organizer
  The 6th Korea-Japan IBD Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Notch signaling regulates expression of Gelsolin superfamily genes, Gelsolin and Scinderin, and promotes re-assembly of actin cytoskelton in human intestinal epithelial cells.2012
- Author(s)
  Okamoto R, Nakamura T, Watanabe M et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Real-Time Analysis of P-Glycoprotein-Mediated Drug Transport Across Primary Intestinal Epithelial Cells Three-Dimensionally Cultured In Vitro2012
- Author(s)
  Tetsuya Nakamura
- Organizer
  Digestive Disease Week 2012
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] 正常大腸上皮幹細胞培養技術を用いた管腔形成機構の解析2012
- Author(s)
  中村哲也
- Organizer
  新学術領域研究「上皮管腔組織形成」第3回領域会議
- Place of Presentation
  仙台
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 単一幹細胞からの大腸上皮大量培養と細胞移植による大腸上皮再生2012
- Author(s)
  中村哲也
- Organizer
  第98回日本消化器病学会総会シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell.2012
- Author(s)
  Tetsuya Nakamura
- Organizer
  ISSCR (International Society for Stem Cell Research) 10th annual meeting.
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] 正常小腸上皮培養細胞を用いたMDR-1依存性薬剤排出機構の解析2012
- Author(s)
  水谷知裕、中村哲也, 他
- Organizer
  第98回日本消化器病学会総会ワークショップ9 (小腸生理機能の基礎医学的解明)
- Place of Presentation
  東京
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Real-time analysis of p-glycoprotein-mediated drug transport across primary intestinal epitherial cells three-dimensionallycultured in vitro2012
- Author(s)
  Mizutani T, Nakamura T, Morikawa R, Fukuda M, Mochizuki W, Yamauchi Y,Nozaki K, Yui S, Okamoto R, Tsuchiya K, Watanabe M
- Organizer
  DDW2012
- Place of Presentation
  San Diego, U.S.A
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PROJECT-23659394
[Presentation] Successful engraftment of colonic epithelium expanded in vitro from a single adult Lgr5+ stem cell2012
- Author(s)
  Tetsuya Nakamura
- Organizer
  9th International Diabetes Federation Western Pacific Region Congress. 4th Scientific Meeting of the Asian Association for the Study of Diabetes.
- Place of Presentation
  Kyoto, Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Real-Time Analysis of P-Glycoprotein-Mediated Drug Transport Across Primary Intestinal Epithelial Cells Three-Dimensionally Cultured In Vitro2012
- Author(s)
  Mizutani T, Nakamura T, et al.
- Organizer
  Digestive Disease Week 2012
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Hes1 promotes IL-22-Mediated epithelial regeneration through enhancement of STAT3-Dpendent transcription in human intestinal epithelial cells.2012
- Author(s)
  Murano T, Okamoto R, Nakamura T, Watanabe M et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 単一幹細胞からの大腸上皮大量培養と細胞移植による大腸上皮再生2012
- Author(s)
  中村哲也、渡辺守
- Organizer
  第98回日本消化器病学会総会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 体外培養した腸管上皮幹細胞による大腸上皮傷害の修復2012
- Author(s)
  中村哲也
- Organizer
  日本臨床免疫学会総会6学会合同特別
- Place of Presentation
  東京
- Year and Date
  2012-09-27
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+stem cells maintained and expanded in vitro2011
- Author(s)
  Shiro Yui, Tetsuya Nakamura, Toshiro Sato, Yasuhiro Nemoto, Tomohiro Mizutani, Xiu Zheng, Shizuko Ichinose, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Hans Clevers, and Mamoru Watanabe
- Organizer
  The 5th Japan & US Collaboration Conference in Gastroenterology
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Regeneration of damaged colonic tissue by transplanted colonic epithelial stem cells maintained and expanded in vitro2011
- Author(s)
  Yui S, Nakamura T, Nemoto Y, Mizutani T, Zheng X, Nagaishi T, Tsuchiya K, Watanabe M, Okamoto R, Ichinose S, Sato T, Clevers H
- Organizer
  GI Research Academy 2011
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Flagellin via TLR5 on basolateral membrane of primary intestinal epithelial cells(IEC) shows the role of IEC in the response to bacteria2011
- Author(s)
  Tsuchiya K, Zheng X, Kano Y, Okamoto R, Nakamura T, Watanabe M
- Organizer
  United European Gastroenterology Week 2011
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Regeneration of Damaged Colonic Tissue by Transplantation of Colonic Epithelial Stem Cells Maintained and Expanded In Vitro2011
- Author(s)
  Shiro Yui, Tetsuya Nakamura, Yasuhiro Nemoto, Tomohiro Mizutani, Xiu Zheng, Shizuko Ichinose, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Toshiro Sato, Hans Clevers, and Mamoru Watanabe
- Organizer
  Basic Science Plenary Symposium, Digestive Disease Week 2011
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Regeneration of Damaged Colonic Tissue by Transplantation of Colonic Epithelial Stem Cells Maintained and Expanded In Vitro2011
- Author(s)
  Yui S, Nakamura T, Watanabe M, et al
- Organizer
  DDW2011
- Place of Presentation
  Chicago
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+stem cells maintained and expanded in vitro2011
- Author(s)
  Shiro Yui, Tetsuya Nakamura, Toshiro Sato, Yasuhiro Nemoto, Tomohiro Mizutani, Xiu Zheng, Shizuko Ichinose, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Hans Clevers, and Mamoru Watanabe
- Organizer
  The5^<th> Japan & US Collaboration Conference in Gastroenterology
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Flagellin via TLR5 on basolateral membrane of primary intestinal epithelial cells(IEC) shows the role of IEC in the response to bacteria.2011
- Author(s)
  Tsuchiya K, Zheng X, Kano Y, Okamoto R, Nakamura T, Watanabe M
- Organizer
  United European Gastroenterology Week 2011
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Regeneration of Damaged Colonic Tissue by Transplantation of Colonic Epithelial Stem Cells Maintained and Expanded In Vitro2011
- Author(s)
  Yui S, Nakamura T, Watanabe M, et al.
- Organizer
  DDW2011
- Place of Presentation
  Chicago
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-22229005
[Presentation] Regeneration of Damaged Colonic Tissue by Transplantation of Colonic Epithelial Stem Cells Maintained and Expanded In Vitro2011
- Author(s)
  Shiro Yui, Tetsuya Nakamura, Yasuhiro Nemoto, Tomohiro Mizutani, Xiu Zheng, Shizuko Ichinose, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Toshiro Sato, Hans Clevers, and Mamoru Watanabe
- Organizer
  Basic Science Plenary Symposium, Digestive DiseaseWeek 2011
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] 再生医療へ向けた腸管上皮研究～幹細胞体外培養と細胞移植～2011
- Author(s)
  中村哲也
- Organizer
  日本消化器病学会総会シンポジウム指定口演
- Place of Presentation
  東京
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Regeneration of damaged colonic tissue by transplanted colonic epithelial stem cells maintained and expanded in vitro2011
- Author(s)
  Yui S, Nakamura T, Nemoto Y, MizutaniT, Zheng X, Nagaishi T, Tsuchiya K, Watanabe M, Okamoto R, Ichinose S, Sato T, Clevers H
- Organizer
  GI Research Academy 2011
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] 再生医療へ向けた腸管上皮研究～幹細胞体外培養と細胞移植～2011
- Author(s)
  中村哲也
- Organizer
  日本消化器病学会総会シンポジウム指定口演
- Place of Presentation
  東京
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] A long-term, mesenchyme-free in vitro culture system of colonic epithelial cells retaining stem cell compartment with proliferation/differentiation properties2010
- Author(s)
  Tetsuya Nakamura, Shiro Yui, Tomohiro Mizutani, Yasuhiro Nemoto, Ryuichi Okamoto, Kiichiro Tsuchiya, Shizuko Ichinose, and Mamoru Watanabe
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] HES1 via notch signaling directly suppresses ATOH1/HATH1 gene transcription, resulting in the undifferentiated state of intestinal epithelial cells.2010
- Author(s)
  Zheng X, Tsuchiya K, Okamoto R, Okamoto E, Iwasaki M, Kano Yoshihito, Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs-
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] A Long-term, fully-defined culture system for colonic epithelial celis that allows efficient expansion of stem cell.2010
- Author(s)
  Nakamura T, Watanabe M, et al.
- Organizer
  The 1st JSGE International Topic Conference
- Place of Presentation
  Kamakura
- Data Source
  KAKENHI-PROJECT-22229005
[Presentation] A Long-term, fully-defined culture system for colonic epithelial cells that allows efficient expansion of stem cell2010
- Author(s)
  Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference
- Place of Presentation
  Kamakura, Japan
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Awell-defined culture system for colonic epithelial cells thet allows efficient enrichment of LGR5+stem cells2010
- Author(s)
  Yui S, Nakamura T, Nemoto Y, MizutaniT, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Up-reguration of DELTA1 expression is required for goblet cell differentiation in human intestinal epithelial cells2010
- Author(s)
  Akiyama J, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] TNF-αand notch signaling synergistically up-regulate OLFM4 expression in human intestinal epithelial cells2010
- Author(s)
  Murano T, Okamoto R, Shimizu H, Akiyama J, Tsuchiya K, Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] Up-reguration of DELTA1 expression is required for goblet cell differentiation in human intestinal epithelial cells2010
- Author(s)
  Akiyama J, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs-
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] Hes1 via Notch signaling directly suppresses Atoh1/Hath1 gene transcription, resulting in the goblet cell depletion of Ulcerative Colitis2010
- Author(s)
  Zheng X, Tsuchiya K, Okamoto R, Iwasaki M, Kano Y, Nakamura T, Watanabe M
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  NewOrleans, USA
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] A long-term, fully-deffined culture system for colonic epithelial cells that alows efficient expansion of stem cell compartment2010
- Author(s)
  Tetsuya Nakamura, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] A well-defined culture system for colonic epithelial cells thet allows efficient enrichment of LGR5+stem cells.2010
- Author(s)
  Yui S, Nakamura T, Nemoto Y, Mizutani T, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs-
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] A long-term, mesenchyme-free in vitro culture system of colonic epithelial cells retaining stem cell compartment with proliferation/differentiation properties.2010
- Author(s)
  Nakamura T, Watanabe M, et al.
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-22229005
[Presentation] Hes1 via Notch signaling directly suppresses Atoh1/Hath1 gene transcription, resulting in the goblet cell depletion of Ulcerative Colitis2010
- Author(s)
  Zheng X, Tsuchiya K, Okamoto R, Iwasaki M, Kano Y, Nakamura T, Watanabe M
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] A long-term, mesenchyme-free in vitro culture system of colonic epithelial cells retaining stem cell compartment with proliferation/differentiation properties.2010
- Author(s)
  Nakamura T, Yui S, Mizutani K, Nemoto Y, Okamoto R, Tsuchiya K, Ichinose S, Watanabe M
- Organizer
  Digestive Disease Week2010
- Place of Presentation
  New Orleans, USAS
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] A long-term, mesenchyme-free in vitro culture system of colonic epithelial cells retaining stem cell compartment with proliferation/differentiation properties2010
- Author(s)
  Tetsuya Nakamura, Shiro Yui, Tomohiro Mizutani, Yasuhiro Nemoto, Ryuichi Okamoto, Kiichiro Tsuchiya, Shizuko Ichinose, and Mamoru Watanabe
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] A long-term, fully-deffined culture system for colonic epithelial cells that alows efficient expansion of stem cell compartment2010
- Author(s)
  Tetsuya Nakamura(Invited speaker), Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs-
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] HES1 via notch signaling directly suppresses ATOH1/HATH1 gene transcription, resulting in the undifferentiated state of intestinal epithelial cells2010
- Author(s)
  Zheng X, Tsuchiya K, Okamoto R, Okamoto E, Iwasaki M, Kano Yoshihito, Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] TNF-αand notch signaling synergistically up-regulate OLFM4 expression in human intestinal epithelial cells2010
- Author(s)
  Murano T, Okamoto R, Shimizu H, Akiyama J, Tsuchiya K, Nakamura T, Watanabe M
- Organizer
  The 1st JSGE International Topic Conference-Stem Cells in Digestive Organs-
- Place of Presentation
  Kamakura, Japan
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] GSK3 inhibitor induces the intestinal differentiation by the protein stabilization of Atoh12009
- Author(s)
  Tsuchiya K, Okamoto R, Nakamura T, Watanabe M
- Organizer
  Digestive Disease Week 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] GSK3 inhibitor induces the intestinal differen tiation by the proteinstabilization of Atoh12009
- Author(s)
  Tsuchiya K, Okamoto R, Nakamura T, Watanabe M
- Organizer
  Digestive Disease Week 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21590803
[Presentation] GSK3 inhibitor induces the intestinal differentiation by the protein stabilization of Atoh1.2009
- Author(s)
  Tsuchiya K, Okamoto R, Nakamura T, Watanabe M
- Organizer
  DDW2009
- Place of Presentation
  シカゴ
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21590805
[Presentation] COMPLETE CONVERSION OF CRYPT PROGENITOR CELLS INTO ATOH1-POSITIVE CELLS BY TARGETED DELETION OF DLL1 AND DLL4 IN LGR5-POSITIVE INTESTINAL STEM CELLS
- Author(s)
  H. Shimizu, R. Okamoto, T. Nakata, S. Fujii, G. Ito, T. Murano, K. Tsuchiya, T. Nakamura, M. Watanabe
- Organizer
  UEGW 2013
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Lineage-specific expression of bestrophin genes in normal and inflamed human intestine: implications for ulcerative colitis.
- Author(s)
  Go Ito, Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Satoru Fujii, Kiichiro Tsuchiya, Tetsuya Nakamura, and Mamoru Watanabe
- Organizer
  The 1st Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  東京、ラフォーレ東京
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Notch signaling regulates expression of Bestrophin-4, a novel enterocyte-specific HCO3-/Cl- channel, in human intestinal epithelial cells.
- Author(s)
  Go Ito, Ryuichi Okamoto, Satoru Fujii, Hiromichi Shimizu, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  DDW 2013
- Place of Presentation
  オーランド、米国
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 培養腸管上皮細胞移植における幹細胞の挙動
- Author(s)
  中村哲也
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+ stem cells maintained and expanded in vitro.
- Author(s)
  Yui S, Nakamura T, Nagaishi T, Watanabe M et al.
- Organizer
  幹細胞シンポジウム
- Place of Presentation
  Awajishima
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] Notch signaling regulates expression of Bestrophin-4, a novel enterocyte-specific HCO3-/Cl- channel, in human intestinal epithelial cells.
- Author(s)
  Go Ito, Ryuichi Okamoto, Satoru Fujii, Hiromichi Shimizu, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  DDW 2013
- Place of Presentation
  オーランド、米国
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] Adult stem cell therapy for gastrointestinal epithelial repair
- Author(s)
  Nakamura Tetsuya
- Organizer
  Taiwanese-Japanese Symposium on Advances of Biomaterials and Regenerative Medicine
- Place of Presentation
  Taipei(Taiwan)
- Invited
- Data Source
  KAKENHI-PROJECT-24390186
[Presentation] 培養上皮幹細胞を用いた消化管再生医療の可能性
- Author(s)
  中村哲也
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] Adult stem cell therapy for gastrointestinal epithelial repair
- Author(s)
  Nakamura Tetsuya
- Organizer
  Taiwanese-Japanese Symposium on Advances of Biomaterials and Regenerative Medicine
- Place of Presentation
  Taipei(Taiwan)
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] IL-22-MEDIATED ANTIMICROBIAL RESPONSE IS REGULATED BY HES1 VIA STAT3-DEPENDENT TRANSCRIPTION IN HUMAN INTESTINAL EPITHELIAL CELLS
- Author(s)
  R. Okamoto, T. Murano, H. Shimizu, G. Ito, S. Fujii, T. Nakata, K. Tsuchiya, T. Nakamura, M. Watanabe
- Organizer
  UEGW 2013
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Complete conversion of crypt progenitor cells into Atoh1-positive cells by targeted deletion of Dll1 and Dll4 in Lgr5-positive intestinal stem cells
- Author(s)
  Hiromichi Shimizu, Ryuichi Okamoto, Satoru Fujii, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  DDW 2013
- Place of Presentation
  オーランド、米国
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Adult stem cell therapy for gastrointestinal epithelial repair
- Author(s)
  Nakamura Tetsuya
- Organizer
  Taiwanese-Japanese Symposium on Advances of Biomaterials and Regenerative Medicine
- Place of Presentation
  Taipei(Taiwan)
- Invited
- Data Source
  KAKENHI-PUBLICLY-24112508
[Presentation] 培養大腸上皮細胞による消化管再生へのアプローチ.
- Author(s)
  中村哲也、渡辺　守
- Organizer
  日本消化器病学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] IL-22-MEDIATED ANTIMICROBIAL RESPONSE IS REGULATED BY HES1 VIA STAT3-DEPENDENT TRANSCRIPTION IN HUMAN INTESTINAL EPITHELIAL CELLS
- Author(s)
  R. Okamoto, T. Murano, H. Shimizu, G. Ito, S. Fujii, T. Nakata, K. Tsuchiya, T. Nakamura, M. Watanabe
- Organizer
  UEGW 2013
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] LINEAGE-SPECIFIC EXPRESSION OF BESTROPHIN-2 AND BESTROPHIN-4 IS REGULATED BY NOTCH SIGNALING IN HUMAN INTESTINAL EPITHELIAL CELLS
- Author(s)
  G. Ito , R. Okamoto, T. Murano, H. Shimizu, K. Tsuchiya, T. Nakamura, M. Watanabe
- Organizer
  UEGW 2013
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] COMPLETE CONVERSION OF CRYPT PROGENITOR CELLS INTO ATOH1-POSITIVE CELLS BY TARGETED DELETION OF DLL1 AND DLL4 IN LGR5-POSITIVE INTESTINAL STEM CELLS
- Author(s)
  H. Shimizu, R. Okamoto, T. Nakata, S. Fujii, G. Ito, T. Murano, K. Tsuchiya, T. Nakamura, M. Watanabe
- Organizer
  UEGW 2013
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] Hes1 promotes IL-22-mediated antimicrobial response through enhancement of STAT3-dependent transcription in human intestinal epithelial cells
- Author(s)
  Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Satoru Fujii, Kiichiro Tsuchiya, Tetsuya Nakamura, and Mamoru Watanabe
- Organizer
  The 1st Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  東京、ラフォーレ東京
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] 培養腸管上皮細胞移植における幹細胞の挙動
- Author(s)
  中村哲也
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] クローン病感受性遺伝子A20による腸炎惹起機構
- Author(s)
  大島　茂、松沢　優、高原政宏、小林正典、仁部洋一、前屋舗千明、永石宇司、土屋輝一郎、岡本隆一、中村哲也、渡辺　守
- Organizer
  厚生労働科学研究難治性疾患克服研究事業「難治性炎症性腸管障害に関する調査研究」
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590936
[Presentation] Hes1 promotes IL-22-mediated antimicrobial response through enhancement of STAT3-dependent transcription in human intestinal epithelial cells
- Author(s)
  Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Satoru Fujii, Kiichiro Tsuchiya, Tetsuya Nakamura, and Mamoru Watanabe
- Organizer
  The 1st Annual Meeting of Asian Organization for Crohn's and Colitis
- Place of Presentation
  東京、ラフォーレ東京
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] LINEAGE-SPECIFIC EXPRESSION OF BESTROPHIN-2 AND BESTROPHIN-4 IS REGULATED BY NOTCH SIGNALING IN HUMAN INTESTINAL EPITHELIAL CELLS
- Author(s)
  G. Ito, R. Okamoto, T. Murano, H. Shimizu, K. Tsuchiya, T. Nakamura, M. Watanabe
- Organizer
  UEGW 2013
- Place of Presentation
  ベルリン、ドイツ
- Data Source
  KAKENHI-PLANNED-23102003
[Presentation] 培養上皮幹細胞を用いた消化管再生医療の可能性
- Author(s)
  中村哲也
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡）
- Invited
- Data Source
  KAKENHI-PROJECT-25670106
[Presentation] Complete conversion of crypt progenitor cells into Atoh1-positive cells by targeted deletion of Dll1 and Dll4 in Lgr5-positive intestinal stem cells
- Author(s)
  Hiromichi Shimizu, Ryuichi Okamoto, Satoru Fujii, Go Ito, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  DDW 2013
- Place of Presentation
  オーランド、米国
- Data Source
  KAKENHI-PROJECT-25293170
[Presentation] 単一幹細胞からの大腸上皮大量培養と細胞移植による大腸上皮再生.
- Author(s)
  中村哲也、渡辺　守
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590936

1. WATANABE Mamoru (10175127)

# of Collaborated Projects: 16 results

# of Collaborated Products: 121 results
2. Matsumoto Yuka (50813672)

# of Collaborated Projects: 10 results

# of Collaborated Products: 17 results
3. Yamataka Atsuyuki (40200703)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
4. 須田一人 (60784725)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
5. TSUCHIYA Kiichiro (40376786)

# of Collaborated Projects: 5 results

# of Collaborated Products: 64 results
6. NAGAISHI Takashi (60447464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. Koga Hiroyuki (30468574)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. HANDA Hiroshi (80107432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. Okamoto Ryuichi (50451935)

# of Collaborated Projects: 2 results

# of Collaborated Products: 53 results
10. AZUMA Miyuki (90255654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ISHIKAWA Hiromichi (20051667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 八木田秀雄 (30182306)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 水島昇 (10353434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ONIZAWA Michio

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. SUZUKI Masahiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. WATABE Taro

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. SUZUKI Shinji (10456212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. ARAKI Akihiro (80361690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. NAGAHORI Masakazu (60420254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KANAI Takanori (40245478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TSUBATA Takeshi (80197756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KIYONO Hiroshi (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Komura Makoto (10422289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 松岡克善 (40307393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 中山泰秀 (50250262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. 鈴木啓介 (50724887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. 藤代準 (60528438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
28. 鈴木完 (80598508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. 澁谷聡一 (80795203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 田中奈々 (50530656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YAMAZAKI Motomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. HOSOYA Akinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. JOSE Nisha

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. WANG Shuan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. TOKAI Arisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
36. TSUGE Naoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. KAWAI Risa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. TSUGAWA Naoya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. YAMADA Daiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KOJIMA Yudai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. HARA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. TOTSUKA Teruji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. MATANO Mami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 永石宇治

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
45. 佐藤俊朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 大塚和朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAMURA Tetsuya 中村 哲也

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Development of technology for in vivo intestinal engineering by transplantation of organoids after epithelial removal by using newly-synthesized chelating agents.Principal Investigator

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Development of novel treatment strategy for intestinal failure based on generation and transplantation of intestinal organoids capable of GLP-2 secretion in an inducible mannerPrincipal Investigator

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Transplantation of small intestinal organoids onto the colon and its potential as a novel therapeutic approach for intestinal failurePrincipal Investigator

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Development of hybrid intestine system and its applicationsPrincipal Investigator

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腸管上皮幹細胞3次元培養技術を利用した管腔形成機構解析Principal Investigator

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NAKAMURA Tetsuya 中村哲也