AKIYAMA Nobutake 秋山暢丈

Researcher Number	00338865
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京慈恵会医科大学, 医学部, 講師 2010 – 2017: 東京慈恵会医科大学, 医学部, 講師 2012: 恵会医科大学, 医学部, 講師 2007 – 2008: Jikei University School of Medicine, 医学部, 助教 2003 – 2004: 東京慈恵会医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 細胞死(アポトーシス) / Tumor therapeutics / Tumor immunology / Biomedical engineering/Biological material science Except Principal Investigator Dermatology / Basic Section 56060:Ophthalmology-related / Mechanobiology
Keywords	Principal Investigator 腫瘍免疫 / CTL / 糖鎖修飾 / TGF-beta / apoptosis / 情報伝達 / TGF-β / アポトーシス / 癌抗原 / アジュバント … More / 癌ワクチン / 糖鎖構造 / 癌免疫 / 細胞障害性T細胞 / リポソーム / ワクチン / 糖鎖 / 抗原提示 / 細胞免疫 / 蛋白質導入 / 機能性素材 / 薬物伝達システム … More Except Principal Investigator IL-31 / 外眼筋 / 筋節長 / DNAマイクロアレイ / 術後の戻り / 斜視 / 筋原性前駆細胞 / Ｘ線回折 / トロポニン / 分子動力学 / X線回折 / 心筋症 / 毛根細胞 / 活性化マクロファージ / ノックインマウス / インターロイキン３１ / 抗体 / IL-31レセプター / 喘息 / アトピー性皮膚炎 / IgE / 掻痒 / 脱毛 / 皮膚病理学 Less

筋原性前駆細胞に対する伸展誘導信号の抑制による「戻り」のない新規斜視治療法の開発
- Principal Investigator
  
  飯田貴絵
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Jikei University School of Medicine
T cell vaccine therapy without epitope determinationsPrincipal Investigator
- Principal Investigator
  
  Nobutake Akiyama
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Jikei University School of Medicine
Establishment of novel CTL inducing vaccine by glycan modificationPrincipal Investigator
- Principal Investigator
  
  NOBUTAKE Akiyama
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor immunology
- Research Institution
  Jikei University School of Medicine
Structural study of cardiomyopathy-causing mutaion revealed by X-ray diffraction and molecular dynamics
- Principal Investigator
  
  YAMAGUCHI Maki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Jikei University School of Medicine
Regulation of the IL-31 function by the blocking antibody to IL-31 receptor
- Principal Investigator
  
  SAITO Saburo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Jikei University School of Medicine
The development of protein delivery systems based on Fmoc-NTA-COOH reagentPrincipal Investigator
- Principal Investigator
  
  AKIYAMA Nobutake
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Jikei University School of Medicine
Analysis of the mechanism of alopecia and pruritis induced by IL-31
- Principal Investigator
  
  SAITO Saburo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Jikei University School of Medicine
The functional analysis of the apoptosis controlling gene TAIP familyPrincipal Investigator
- Principal Investigator
  
  AKIYAMA Nobutake
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Jikei University School of Medicine

All 2014 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] IL-31によるIgE産生増強とその機序2010
- Author(s)
  斎藤三郎,秋山暢丈
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 53(1) Pages: 16-20
- Data Source
  KAKENHI-PROJECT-22591230
[Journal Article] Enhancing activity of N-glycosylation for constitutive proteins secretionsin non-polarized cells2009
- Author(s)
  Nobutake Akiyama, Yuji Ohno, Takahiro Fukuda, Yosinobu Manome, Saburo Saito
- Journal Title
  
  Biochemical and Biophysical Research Communications 381
  
  Pages: 612-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500408
[Journal Article] Enhancing activity of N-glycosylation for constitutive proteins secretionsin non-polarized cells2009
- Author(s)
  Nobutake Akiyama, Yuji Ohno. Takahiro Fukuda. Yosinobu Manome, Saburo Saito
- Journal Title
  
  Biochemical and Biophysical Research Communications 381
  
  Pages: 612-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500408
[Journal Article] Enhancing activity of N-glycosylation for constitutive proteins secretions in non-polarized cells2009
- Author(s)
  Nobutake Akiyama, Yuji Ohno, Takahiro Fukuda, Yosinobu Manome, Saburo Saito
- Journal Title
  
  Biochemical and Biophysical Research Communications Volume 381, Issue 4
  
  Pages: 612-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591329
[Journal Article] IL-31の多面的機能2008
- Author(s)
  斎藤三郎, 秋山暢丈
- Journal Title
  
  臨床免疫・アレルギー科 50(6)
  
  Pages: 640-643
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] Enhancement of CTL induction with cationic liposome by the modification of N-glycan structure2014
- Author(s)
  秋山暢丈
- Organizer
  日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-26640107
[Presentation] IL-31 increases IgE levels in mice2008
- Author(s)
  Saito Saburo, Akiyama Nobutake, Kohno Hideo, Ohno Yuji
- Organizer
  The XXVII Congress of European Academy of Allergology and Clinical Immunology
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] 喘息患者末梢血単核球のIL-31産生能2008
- Author(s)
  飯倉克人, 谷野千鶴子, 佐藤哲夫, 勝沼俊雄, 中川秀巳, 永田欽也, 秋山暢丈, 斎藤三郎
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] IL-31は血清IgEレベルを増強する2008
- Author(s)
  斎藤三郎, 秋山暢丈, 神野英生, 大野裕治
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] IL-31投与によるマウス血清IgEレベルの上昇2008
- Author(s)
  斎藤三郎, 秋山暢丈, 大野裕治, 神野英生, 谷野千鶴子, 飯倉克人
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] IL-31過剰発現マウスの皮膚症状と血清IgEレベル2007
- Author(s)
  斎藤三郎、秋山暢丈
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] IgE responses triggered by IL-312007
- Author(s)
  Saito Saburo, Akiyama Nobutake
- Organizer
  XXVI Congress of the European Academy of Allergology and Clinical Immunology
- Place of Presentation
  Sweden
- Year and Date
  2007-06-12
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] Enhanced serum IgE levels in IL-31 transgenic mice2007
- Author(s)
  斎藤三郎、秋山暢丈
- Organizer
  第37回日本免疫学会総会・学術大会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19591329
[Presentation] 日本免疫学会
- Author(s)
  秋山暢丈
- Organizer
  Enhancement of CTL induction with cationic liposome by the modification of N-glycan structure
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-23501290

1. SAITO Saburo (10186934)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. WATANABE Michiko (10158660)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YAMAGUCHI Maki (30271315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MANOME Yoshinobu (30219539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. OHNO Yuji (60142478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. TAKEMORI Shigeru (20179675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OHNO Tetsuo (30233224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KIMURA Masako (30328314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMADA Hisashi (20130213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KONDOH Shinae (40314182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 飯田貴絵 (00897168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山澤徳志子 (00282616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中原直哉 (10632193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AKIYAMA Nobutake 秋山 暢丈

Research Projects

Research Products

Co-Researchers

筋原性前駆細胞に対する伸展誘導信号の抑制による「戻り」のない新規斜視治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

T cell vaccine therapy without epitope determinationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of novel CTL inducing vaccine by glycan modificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural study of cardiomyopathy-causing mutaion revealed by X-ray diffraction and molecular dynamics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of the IL-31 function by the blocking antibody to IL-31 receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of protein delivery systems based on Fmoc-NTA-COOH reagentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism of alopecia and pruritis induced by IL-31

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The functional analysis of the apoptosis controlling gene TAIP familyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-31によるIgE産生増強とその機序2010

Author(s)

Journal Title

Data Source

[Journal Article] Enhancing activity of N-glycosylation for constitutive proteins secretionsin non-polarized cells2009

Author(s)

Journal Title

Data Source

[Journal Article] Enhancing activity of N-glycosylation for constitutive proteins secretionsin non-polarized cells2009

Author(s)

Journal Title

Data Source

[Journal Article] Enhancing activity of N-glycosylation for constitutive proteins secretions in non-polarized cells2009

Author(s)

Journal Title

Data Source

[Journal Article] IL-31の多面的機能2008

Author(s)

Journal Title

Data Source

[Presentation] Enhancement of CTL induction with cationic liposome by the modification of N-glycan structure2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IL-31 increases IgE levels in mice2008

Author(s)

AKIYAMA Nobutake 秋山暢丈