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Saiki Shinji  斉木 臣二

… Alternative Names

SAIKI Shinji  斉木 臣二

斉木 臣二  サイキ シンジ

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Researcher Number 00339996
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9732-8488
Affiliation (Current) 2025: 筑波大学, 医学医療系, 教授
2025: 順天堂大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 筑波大学, 医学医療系, 教授
2023: 筑波大学, 医学部, 教授
2023: 順天堂大学, 大学院医学研究科, 客員教授
2021 – 2023: 順天堂大学, 医学部, 客員教授
2021: 順天堂大学, 医学部, 先任准教授 … More
2012 – 2021: 順天堂大学, 医学部, 准教授
2011: 順天堂大学, 順天堂大学, 准教授
2009 – 2010: Juntendo University, 医学部, 助手
2003: 金沢医大, 医学部, 助手
2002: 金沢医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields / Complex Systems Disease Theory / Biological Sciences / Neurology
Except Principal Investigator
Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Biological Sciences / Basic Section 37030:Chemical biology-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields … More / Broad Section I / Medium-sized Section 52:General internal medicine and related fields / Basic Section 52020:Neurology-related / Food science / Biomolecular chemistry Less
Keywords
Principal Investigator
オートファジー / パーキンソン病 / ポリアミン / 神経変性疾患 / メタボローム解析 / リソソーム / 神経内科学 / 自律神経 / 臓器連関 / 脂肪酸β酸化 … More / 遠隔効果 / miRNA / 脳・神経 / 内科 / ケミカルバイオロジー / 蛋白分解 / 国際情報交換 / 脳神経疾患 / 機械学習 / 微小管中心 / 腸脳連関 / 腸内細菌叢 / 脂肪酸代謝 / 臓器円環 / 肝臓 / 甲状腺 / 骨格筋 / ポリアミン代謝 / カフェイン代謝 / 代謝産物 / ES細胞 / iPS細胞 / 代謝 / ミトコンドリア / スペルミジン / スペルミン / ジアセチルスペルミジン / バイオマーカー / 神経変性 / 小分子化合物 / 創薬シーズ / マイトファジー / 細胞死 / 再生医療 / ミトファジー / グルタミン酸レセプター / Ca^<2+>流入 / excitotoxicity / アストロサイト / オリゴデンドロサイト … More
Except Principal Investigator
パーキンソン病 / オートファジー / 神経変性疾患 / α-synuclein (αS) / レヴィ小体 / ケミカルバイオロジー / バイオマーカー / アグリソーム / 相分離 / パーキンソン疾患 / パーキンソン / 遺伝子 / リソソーム / 細胞内分解 / alpha-Synuclein / ゼノファジー / DNAメチル化 / Fusobacterium nucleatum / コリバクチン産生大腸菌 / ポリアミン / 疾患修飾療法 / シヌクレイノパチー / 多系統萎縮症 (MSA) / パーキンソン病 (PD) / 多系統萎縮(MSA) / α-Synuclein(αS) / パーキンソン病(PD) / 多系統萎縮(MSA) / α-Synuclein(αS) / パーキンソン病(PD) / ユビキリン / αシヌクレイン / 液-液相分離 / アルファシヌクレイン / パーキンソン症 / 凝集タンパク質 / ビリルビン / タンパク質凝集 / メタボローム 解析 / ゲノム / 神経細胞死 / iPS細胞 / エクソーム / 神経細胞変性 / ドーパミン / 原因遺伝子 / 次世代シーケンサー / 網膜色素変性症 / 神経科学 / カフェイン代謝 / 代謝 / カフェイン / がん / 脳神経疾患 / 生理学 / 細胞・組織 / 蛋白質 Less
  • Research Projects

    (22 results)
  • Research Products

    (187 results)
  • Co-Researchers

    (52 People)
  •  Elucidation of mechanism of propagation and aggregation of alpha-synuclein and development of disease-modifying therapies

    • Principal Investigator
      服部 信孝
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      Juntendo University
  •  New strategy for preventing colorectal cancer by targeting polyamines, which are thought to be carcinogens

    • Principal Investigator
      松本 光晴
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kyodo Milk Industry Co., Ltd.
  •  細胞内alpha-Synuclein凝集制御機構を解析するケミカルバイオロジー

    • Principal Investigator
      北川 光洋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Juntendo University
  •  Research on microbiome-gut axis in initial pathogenesis of Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      Saiki Shinji
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      University of Tsukuba
  •  Development of anti-Parkinson's disease drugs enhancing neuronal autophagyPrincipal Investigator

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      University of Tsukuba
  •  Studies on the regulatory mechanism of aggresome formatiion and clearance

    • Principal Investigator
      Imoto Masaya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Juntendo University
  •  Elucidation of transmission and aggregation mechanisms of alpha-synuclein as a major component of Lewy body and development of disease-modifying therapies for synucleinopathies

    • Principal Investigator
      Hattori Nobutaka
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University
  •  Elucidation of the molecular mechanisms of dopaminergic neurodegenerative disorders using a large genome resource

    • Principal Investigator
      Funayama Manabu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University
  •  Research on PD pathogenesis based on polyamine metabolism using multiomics analysisPrincipal Investigator

    • Principal Investigator
      Saiki Shinji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Complex Systems Disease Theory
    • Research Institution
      Juntendo University
  •  Identification of Parkinson disease-specific mitochondrial pathogenesis for disease-modifying therapyPrincipal Investigator

    • Principal Investigator
      Saiki Shinji
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University
  •  Identification of Parkinson's disease progression markers based on skeletal muscle-brain axisPrincipal Investigator

    • Principal Investigator
      Saiki Shinji
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University
  •  Chemical Biology for Parkinson's disease

    • Principal Investigator
      Imoto Masaya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Juntendo University
      Keio University
  •  Examination of Caffeine Metabolism Changes and Parkinson's Disease Symptom Correlation Based on Metabolite-Related Gene Analysis

    • Principal Investigator
      SUMIYOSHI KATSUHIKO
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Tokiwa University
  •  International Activities Support for Autophagy Research

    • Principal Investigator
      Mizushima Noboru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Chemical Biological studies for autophagy

    • Principal Investigator
      IMOTO MASAYA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Keio University
  •  Development of anti-PD chemicals modulating autophagic activity based on lysosomal functionPrincipal Investigator

    • Principal Investigator
      Shinji Saiki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  Multidisciplinary research on autophagy: from molecular mechanisms to disease states

    • Principal Investigator
      Mizushima Noboru
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Development of autophagy enhancing chemicals based on Parkinson's disease pathogenesis.Principal Investigator

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  Analysis of mitochondrial regeneration with cellular models of Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  Effects of A2A-receptor antagonists on PD models via autophagy regulation.Principal Investigator

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  Effects of mitophagy on cell death in Parkinson's disease model cellsPrincipal Investigator

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  アストログリアにおけるexcitotoxicityの研究Principal Investigator

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Kanazawa Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

  • [Book] Development of autophagy enhancers for Parkinson’s disease(pp305-320), Autophagy Dysfunction in Alzheimer's Disease and Dementia2022

    • Author(s)
      Sasazawa Y, Hattori N, Saiki S
    • Total Pages
      356
    • Publisher
      Academic Press Book-Elsevier, UK
    • ISBN
      9780323899062
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Book] Methods in Molecular Biology, Mitophagy2017

    • Author(s)
      Shinji Saiki, Nobutaka Hattori
    • Total Pages
      200
    • Publisher
      Splinger
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Book] Parkinson's disease and Movement Disorders, 6th edition2015

    • Author(s)
      Shinji Saiki
    • Total Pages
      644
    • Publisher
      Lippincott Williams and Wilkins
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Book] Parkinson's disease and Movement Disorders, 6th edition2015

    • Author(s)
      Shinji Saiki
    • Total Pages
      644
    • Publisher
      Lippincott Williams and Wilkins
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Book] Clinical Neuroscience2015

    • Author(s)
      斉木臣二
    • Total Pages
      130
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Book] Clinical Neuroscience2015

    • Author(s)
      斉木臣二
    • Total Pages
      130
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Book] Neuroacanthocytosis. In : Jankovic J, Tolosa E, eds. Parkinson's disease and movement disorders. 6th ed. Philadelphia, PA : Lippincott Williams & Wilkins2014

    • Author(s)
      Saiki S
    • Publisher
      (in press)
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Book] Neuroacanthocytosis. In : Jankovic J, Tolosa E, eds. Parkinson's disease and movement disorders. 6th ed. Philadelphia2014

    • Author(s)
      Saiki S.
    • Publisher
      PA : Lippincott Williams & Wilkins(in press)
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Journal Article] Free-water diffusion magnetic resonance imaging under selegiline treatment in Parkinson's disease2024

    • Author(s)
      Takeshige-Amano Haruka、Hatano Taku、Kamagata Koji、Andica Christina、Ogawa Takashi、Shindo Atsuhiko、Uchida Wataru、Sako Wataru、Saiki Shinji、Shimo Yasushi、Oyama Genko、Umemura Atsushi、Ito Masanobu、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 457 Pages: 122883-122883

    • DOI

      10.1016/j.jns.2024.122883

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K11880, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-21H04820
  • [Journal Article] Propagative α-synuclein seeds as serum biomarkers for synucleinopathies.2023

    • Author(s)
      Ayami Okuzumi Taku Hatano Gen Matsumoto Nobutaka Hattori et al
    • Journal Title

      Nature medicine

      Volume: 29 Issue: 6 Pages: 1448-1455

    • DOI

      10.1038/s41591-023-02358-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14785, KAKENHI-PROJECT-21K07283, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-21K07444, KAKENHI-PUBLICLY-22H04651, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-23K24214
  • [Journal Article] Identification of novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease2023

    • Author(s)
      Date Yuki、Sasazawa Yukiko、Kitagawa Mitsuhiro、Gejima Kentaro、Suzuki Ayami、Saya Hideyuki、Imoto Masaya、Itakura Eisuke、Hattori Nobutaka、Saiki Shinji
    • Journal Title

      biorxiv

      Volume: -

    • DOI

      10.1101/2023.11.07.566147

    • Open Access
    • Data Source
      KAKENHI-PROJECT-22K19512, KAKENHI-PROJECT-23K24247
  • [Journal Article] JNK‐interacting protein 4 is a central molecule for lysosomal retrograde trafficking2023

    • Author(s)
      Sasazawa Y, Hattori N, Saiki S
    • Journal Title

      BioEssays

      Volume: 45 Issue: 11

    • DOI

      10.1002/bies.202300052

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07425, KAKENHI-PROJECT-22K19512, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-23K24247
  • [Journal Article] Oxidative stress‐induced phosphorylation of JIP4 regulates lysosomal positioning in coordination with TRPML1 and ALG22022

    • Author(s)
      Sasazawa Yukiko、Souma Sanae、Furuya Norihiko、Miura Yoshiki、Kazuno Saiko、Kakuta Soichiro、Suzuki Ayami、Hashimoto Ryota、Hirawake‐Mogi Hiroko、Date Yuki、Imoto Masaya、Ueno Takashi、Kataura Tetsushi、Korolchuk Viktor I、Tsunemi Taiji、Hattori Nobutaka、Saiki Shinji
    • Journal Title

      The EMBO Journal

      Volume: 41 Issue: 22

    • DOI

      10.15252/embj.2022111476

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07425, KAKENHI-PROJECT-21K07444, KAKENHI-PROJECT-22K19512, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-21H02072, KAKENHI-PROJECT-23K24247
  • [Journal Article] Systemic Metabolic Alteration Dependent on the Thyroid‐Liver Axis in Early <scp>PD</scp>2022

    • Author(s)
      Miyamoto Kengo、Saiki Shinji、Matsumoto Hirotaka、Suzuki Ayami、Yamashita Yuri、Iseki Tatou、Ueno Shin‐Ichi、Shiina Kenta、Kataura Tetsushi、Kamagata Koji、Imamichi Yoko、Sasazawa Yukiko、Fujimaki Motoki、Akamatsu Wado、Hattori Nobutaka
    • Journal Title

      Annals of Neurology

      Volume: 93 Issue: 2 Pages: 303-316

    • DOI

      10.1002/ana.26510

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07425, KAKENHI-PROJECT-22K19512, KAKENHI-PROJECT-22K17810, KAKENHI-PROJECT-23K24247, KAKENHI-PROJECT-21H04820
  • [Journal Article] Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning2021

    • Author(s)
      Uehara Yuya、Ueno Shin-Ichi、Amano-Takeshige Haruka、Suzuki Shuji、Imamichi Yoko、Fujimaki Motoki、Ota Noriyasu、Murase Takatoshi、Inoue Takayoshi、Saiki Shinji、Hattori Nobutaka
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 18550-18550

    • DOI

      10.1038/s41598-021-98423-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-21H04820
  • [Journal Article] Metabolomic analysis data of MPP+-exposed SH-SY5Y cells using CE-TOFMS2021

    • Author(s)
      Amo Taku、Oji Yutaka、Saiki Shinji、Hattori Nobutaka
    • Journal Title

      Data in Brief

      Volume: 34 Pages: 106707-106707

    • DOI

      10.1016/j.dib.2020.106707

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07878, KAKENHI-PROJECT-18KK0242, KAKENHI-PROJECT-17K09769, KAKENHI-PROJECT-18H02744
  • [Journal Article] Clinical manifestations of Parkinson's disease harboring VPS35 retromer complex component p.D620N with long-term follow-up2021

    • Author(s)
      Ishiguro Mayu、Li Yuanzhe、Yoshino Hiroyo、Daida Kensuke、Ishiguro Yuta、Oyama Genko、Saiki Shinji、Funayama Manabu、Hattori Nobutaka、Nishioka Kenya
    • Journal Title

      Parkinsonism & Related Disorders

      Volume: 84 Pages: 139-143

    • DOI

      10.1016/j.parkreldis.2021.02.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-20K07893, KAKENHI-PROJECT-21H04820
  • [Journal Article] Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease2021

    • Author(s)
      Koinuma Takahiro、Hatano Taku、Kamagata Koji、Andica Christina、Mori Akio、Ogawa Takashi、Takeshige-Amano Haruka、Uchida Wataru、Saiki Shinji、Okuzumi Ayami、Ueno Shin-Ichi、Oji Yutaka、Saito Yuya、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Journal of Parkinson's Disease

      Volume: - Issue: 3 Pages: 1-15

    • DOI

      10.3233/jpd-202495

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17244, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18H02772, KAKENHI-PROJECT-20F20113, KAKENHI-PROJECT-21K07424
  • [Journal Article] Intrajejunal Infusion of Levodopa/Carbidopa for Advanced Parkinson's Disease: A Systematic Review2021

    • Author(s)
      Tsunemi Taiji、Oyama Genko、Saiki Shinji、Hatano Taku、Fukae Jiro、Shimo Yasushi、Hattori Nobutaka
    • Journal Title

      Movement Disorders

      Volume: 36 Issue: 8 Pages: 1759-1771

    • DOI

      10.1002/mds.28595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers2020

    • Author(s)
      Kataura Tetsushi、Tashiro Etsu、Nishikawa Shota、Shibahara Kensuke、Muraoka Yoshihito、Miura Masahiro、Sakai Shun、Katoh Naohiro、Totsuka Misato、Onodera Masafumi、Shin-Ya Kazuo、Miyamoto Kengo、Sasazawa Yukiko、Hattori Nobutaka、Saiki Shinji、Imoto Masaya
    • Journal Title

      Autophagy

      Volume: Aug 7 Issue: 8 Pages: 1-17

    • DOI

      10.1080/15548627.2020.1794590

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05732, KAKENHI-PROJECT-18KK0242, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-20H05340, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-16H06276
  • [Journal Article] Shared Metabolic Profile of Caffeine in Parkinsonian Disorders2020

    • Author(s)
      Takeshige-Amano H, Saiki S, Fujimaki M, Ueno SI, Li Y, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, Tsunemi T, Daida K, Ishiguro Y, Imamichi Y, Nanmo H, Nojiri S, Funayama M, Hattori N.
    • Journal Title

      Mov Disord

      Volume: 35 Pages: 1438-1447

    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] BRUP-1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson’s disease model.2020

    • Author(s)
      Kataura, T., Saiki, S., Ishikawa, K., Akamatsu, W., Sasazawa, Y., Hattori, N., Imoto, M.
    • Journal Title

      J. Neurochemstry

      Volume: - Issue: 1 Pages: 81-97

    • DOI

      10.1111/jnc.14997

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19J12969, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-18K15464, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-20H05340, KAKENHI-PROJECT-18H02099
  • [Journal Article] Shared Metabolic Profile of Caffeine in Parkinsonian Disorders2020

    • Author(s)
      Takeshige‐Amano Haruka、Saiki Shinji、Fujimaki Motoki、Ueno Shin‐Ichi、Li Yuanzhe、Hatano Taku、Ishikawa Kei‐Ichi、Oji Yutaka、Mori Akio、Okuzumi Ayami、Tsunemi Taiji、Daida Kensuke、Ishiguro Yuta、Imamichi Yoko、Nanmo Hisayoshi、Nojiri Shuko、Funayama Manabu、Hattori Nobutaka
    • Journal Title

      Movement Disorders

      Volume: 35 Issue: 8 Pages: 1438-1447

    • DOI

      10.1002/mds.28068

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K07510, KAKENHI-PROJECT-18KT0027
  • [Journal Article] Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease2020

    • Author(s)
      Yamaguchi A, Ishikawa KI, Inoshita T, Shiba-Fukushima K, Saiki S, Hatano T, Mori A, Oji Y, Okuzumi A, Li Y, Funayama M, Imai Y, Hattori N, Akamatsu W.
    • Journal Title

      Stem Cell Reports

      Volume: 14 Pages: 1060-1075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease2020

    • Author(s)
      Yamaguchi Akihiro、Ishikawa Kei-ichi、Inoshita Tsuyoshi、Shiba-Fukushima Kahori、Saiki Shinji、Hatano Taku、Mori Akio、Oji Yutaka、Okuzumi Ayami、Li Yuanzhe、Funayama Manabu、Imai Yuzuru、Hattori Nobutaka、Akamatsu Wado
    • Journal Title

      Stem Cell Reports

      Volume: 14 Issue: 6 Pages: 1060-1075

    • DOI

      10.1016/j.stemcr.2020.04.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-20K07873, KAKENHI-PROJECT-20K07910, KAKENHI-PROJECT-17H04049, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-17K09765
  • [Journal Article] Metabolomics‐based identification of metabolic alterations in PARK22019

    • Author(s)
      Okuzumi Ayami、Hatano Taku、Ueno Shin‐Ichi、Ogawa Takashi、Saiki Shinji、Mori Akio、Koinuma Takahiro、Oji Yutaka、Ishikawa Kei‐Ichi、Fujimaki Motoki、Sato Shigeto、Ramamoorthy Sivapriya、Mohney Robert P.、Hattori Nobutaka
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 6 Issue: 3 Pages: 525-536

    • DOI

      10.1002/acn3.724

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-19K22603
  • [Journal Article] Mutations in CHCHD2 cause α-synuclein aggregation2019

    • Author(s)
      Ikeda A., Nishioka K., Meng H., Takanashi M., Hasegawa I., Inoshita T., Shiba-Fukushima K., Li Y., Yoshino H., Mori A., Okuzumi A., Yamaguchi A., Nonaka R., Izawa N., Ishikawa K.I., Saiki H., Morita M., Hasegawa M., Hasegawa K., Elahi M., et al.
    • Journal Title

      Human Molecular Genetics

      Volume: 28 Issue: 23 Pages: 3895-3911

    • DOI

      10.1093/hmg/ddz241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-18K15465
  • [Journal Article] Metabolomic analysis revealed mitochondrial dysfunction and aberrant choline metabolism in MPP+-exposed SH-SY5Y cells2019

    • Author(s)
      Amo Taku、Oji Yutaka、Saiki Shinji、Hattori Nobutaka
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 519 Issue: 3 Pages: 540-546

    • DOI

      10.1016/j.bbrc.2019.09.031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K09769, KAKENHI-PROJECT-18H02744
  • [Journal Article] p150glued deficiency impairs effective fusion between autophagosomes and lysosomes due to their redistribution to the cell periphery.2019

    • Author(s)
      Ishikawa-KI, Saiki S, Furuya N, Imamichi Y, Tsuboi Y, Hattori N
    • Journal Title

      Neuroscience Letters

      Volume: 690 Pages: 181-187

    • DOI

      10.1016/j.neulet.2018.10.036

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-18H02744
  • [Journal Article] Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy2019

    • Author(s)
      Mori Akio、Ishikawa Kei-Ichi、Saiki Shinji、Hatano Taku、Oji Yutaka、Okuzumi Ayami、Fujimaki Motoki、Koinuma Takahiro、Ueno Shin-Ichi、Imamichi Yoko、Hattori Nobutaka
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 9 Pages: e0223113-e0223113

    • DOI

      10.1371/journal.pone.0223113

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18K15376, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15463
  • [Journal Article] A metabolic profile of polyamines in parkinson disease: A promising biomarker2019

    • Author(s)
      Saiki Shinji、Sasazawa Yukiko、Fujimaki Motoki、Kamagata Koji、Kaga Naoko、Taka Hikari、Li Yuanzhe、Souma Sanae、Hatano Taku、Imamichi Yoko、Furuya Norihiko、Mori Akio、Oji Yutaka、Ueno Shin‐Ichi、Nojiri Shuko、Miura Yoshiki、Ueno Takashi、Funayama Manabu、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Annals of Neurology

      Volume: 86 Issue: 2 Pages: 251-263

    • DOI

      10.1002/ana.25516

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15464
  • [Journal Article] Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions2019

    • Author(s)
      Fujimaki Motoki、Furuya Norihiko、Saiki Shinji、Amo Taku、Imamichi Yoko、Hattori Nobutaka
    • Journal Title

      Molecular and Cellular Biology

      Volume: 39 Issue: 14

    • DOI

      10.1128/mcb.00010-19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K09769, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744
  • [Journal Article] Neuroprotective effects of memantine via enhancement of autophagy2019

    • Author(s)
      Hirano Kazuoki、Fujimaki Motoki、Sasazawa Yukiko、Yamaguchi Akihiro、Ishikawa Kei-Ichi、Miyamoto Kengo、Souma Sanae、Furuya Norihiko、Imamichi Yoko、Yamada Daisuke、Saya Hideyuki、Akamatsu Wado、Saiki Shinji、Hattori Nobutaka
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 518 Issue: 1 Pages: 161-170

    • DOI

      10.1016/j.bbrc.2019.08.025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-18K15464
  • [Journal Article] Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease2018

    • Author(s)
      Motoki Fujimaki, Shinji Saiki, Yuanzhe Li, Naoko Kaga, Taku Hatano, Kei-Ichi Ishikawa, Yutaka Oji, Akio Mori, Ayami Okuzumi, Takahiro Koinuma, Shin-Ichi Ueno, Yoko Imamichi, Takashi Ueno, Yoshiki Miura, Manabu Funayama
    • Journal Title

      Neurology

      Volume: 90

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Journal Article] Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease2018

    • Author(s)
      Ren Qian、Ma Min、Yang Jun、Nonaka Risa、Yamaguchi Akihiro、Ishikawa Kei-ichi、Kobayashi Kenta、Murayama Shigeo、Hwang Sung Hee、Saiki Shinji、Akamatsu Wado、Hattori Nobutaka、Hammock Bruce D.、Hashimoto Kenji
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 115 Issue: 25

    • DOI

      10.1073/pnas.1802179115

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K06535, KAKENHI-PROJECT-18K15463, KAKENHI-PUBLICLY-17H05706, KAKENHI-PROJECT-17H04243, KAKENHI-PROJECT-16K09677, KAKENHI-PROJECT-18K15439
  • [Journal Article] Randomized, double-blind, multicenter trial of hydrogen water for Parkinson's disease2018

    • Author(s)
      Yoritaka Asako、Ohtsuka Chigumi、Maeda Tetsuya、Hirayama Masaaki、Abe Takashi、Watanabe Hirohisa、Saiki Hidemoto、Oyama Genko、Fukae Jiro、Shimo Yasushi、Hatano Taku、Hattori Nobutaka、et al
    • Journal Title

      Movement Disorders

      Volume: 33 Issue: 9 Pages: 1505-1507

    • DOI

      10.1002/mds.27472

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16K09675
  • [Journal Article] Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice.2018

    • Author(s)
      Sato S, Uchihara T, Fukuda T, Noda S, Kondo H, Saiki S, Komatsu M, Uchiyama Y, Tanaka K, Hattori N.
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 2813-2813

    • DOI

      10.1038/s41598-018-21325-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06780, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16K14572, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-25111007, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-15H04843, KAKENHI-PROJECT-17H03555, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-18H04043
  • [Journal Article] Zonisamide Administration Improves Fatty Acid β-Oxidation in Parkinson's Disease.2018

    • Author(s)
      Ueno SI, Saiki S, Fujimaki M, Takeshige-Amano H, Hatano T, Oyama G, Ishikawa KI, Yamguchi A, Nojiri S, Akamatsu W, Hattori N.
    • Journal Title

      Cells

      Volume: 8 Issue: 1 Pages: 14-14

    • DOI

      10.3390/cells8010014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K15463, KAKENHI-PUBLICLY-17H05706, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09677
  • [Journal Article] Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease.2018

    • Author(s)
      Fujimaki M, Saiki S, Li Y, Kaga N, Taka H, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, Koinuma T, Ueno SI, Imamichi Y, Ueno T, Miura Y, Funayama M, Hattori N.
    • Journal Title

      Neurology.

      Volume: 90 Issue: 5 Pages: 1-8

    • DOI

      10.1212/wnl.0000000000004888

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01834, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K09700, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-15KK0354, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-18H04043
  • [Journal Article] Serum caffeine and metabolites are reliable biomarkers of early Parkinson’s disease.2018

    • Author(s)
      3.Fujimaki M, Saiki S*, Li Y, Kaga N, Taka H, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, Koinuma T, Ueno SI, Imamichi Y, Ueno T, Miura Y, Funayama M, Hattori N
    • Journal Title

      Neurology

      Volume: 9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Journal Article] NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.2018

    • Author(s)
      Furuya N, Kakuta S, Sumiyoshi K, Ando M, Nonaka R, Suzuki A, Kazuno S, Saiki S, Hattori N.
    • Journal Title

      EMBO Reports

      Volume: 19 Issue: 12

    • DOI

      10.15252/embr.201846363

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-17K15550, KAKENHI-PROJECT-18H02744
  • [Journal Article] Connectome analysis with diffusion MRI in idiopathic Parkinson's disease: Evaluation using multi-shell, multi-tissue, constrained spherical deconvolution.2017

    • Author(s)
      Kamagata K, Zalesky A, Hatano T, Di Biase MA, El Samad O, Saiki S, Shimoji K, Kumamaru KK, Kamiya K, Hori M, Hattori N, Aoki S, Pantelis C.
    • Journal Title

      Neuroimage Clinical

      Volume: 17 Pages: 518-529

    • DOI

      10.1016/j.nicl.2017.11.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-15K09944, KAKENHI-PROJECT-16K19854
  • [Journal Article] パーキンソン病とオートファジー2017

    • Author(s)
      斉木臣二
    • Journal Title

      最新医学

      Volume: 72 Pages: 177-183

    • Data Source
      KAKENHI-PLANNED-25111007
  • [Journal Article] Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson's disease.2017

    • Author(s)
      Saiki S, Hatano T, Fujimaki M, Ishikawa K, Mori A, Oji Y, Okuzumi A, Fukuhara T, Koinuma T, Nagumo M, Furuya N, Nojiri S, Amo T, Yamashiro K, Hattori N.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 7328-7328

    • DOI

      10.1038/s41598-017-06767-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-17K09769, KAKENHI-PLANNED-25111007, KAKENHI-PROJECT-15H04843, KAKENHI-PROJECT-15K09325
  • [Journal Article] Immunocytochemical Monitoring of PINK1/Parkin-Mediated Mitophagy in Cultured Cells.2017

    • Author(s)
      Fujimaki, M., Saiki, S., Sasazawa, Y., Ishikawa, KI., Imamichi, Y., Sumiyoshi, K &, Hattori, N.
    • Journal Title

      Methods Mol Biol.

      Volume: 印刷中 Pages: 19-27

    • DOI

      10.1007/7651_2017_20

    • ISBN
      9781493977499, 9781493977505
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16J40133, KAKENHI-PROJECT-17K07797
  • [Journal Article] パーキンソン病とオートファジー2017

    • Author(s)
      斉木臣二
    • Journal Title

      最新医学

      Volume: 72 Pages: 177-183

    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Journal Article] Ethambutol neutralizes lysosomes and causes lysosomal zinc accumulation.2015

    • Author(s)
      Yamada D, Saiki S, Furuya N, Ishikawa K, Imamichi Y, Kambe T, Fujimura T, Ueno T, Koike M, Sumiyoshi K, Hattori N
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 471 Issue: 1 Pages: 109-116

    • DOI

      10.1016/j.bbrc.2016.01.171

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09325, KAKENHI-PUBLICLY-15H01388, KAKENHI-PLANNED-23111003, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-15H04501, KAKENHI-PROJECT-15H04843, KAKENHI-PROJECT-26893263, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-26660086, KAKENHI-PLANNED-25111007, KAKENHI-PROJECT-15H04842
  • [Journal Article] Identification of novel biomarkers for Parkinson's disease by metabolomic technologies.2015

    • Author(s)
      Hatano T, Saiki S, Okuzumi A, Mohney RP, Hattori N.
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: jnnp-2014 Issue: 3 Pages: 2014-309676

    • DOI

      10.1136/jnnp-2014-309676

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-ORGANIZER-25111001, KAKENHI-PROJECT-25461290, KAKENHI-PLANNED-25111007
  • [Journal Article] VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process.2015

    • Author(s)
      Fuse A, Furuya N, Kakuta S, Inose A, Sato M, Koike M, Saiki S, Hattori N
    • Journal Title

      FEBS Lett.

      Volume: 589 Issue: 13 Pages: 1430-1436

    • DOI

      10.1016/j.febslet.2015.04.040

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09325, KAKENHI-PUBLICLY-15H01388, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-15H04843, KAKENHI-PROJECT-25460276
  • [Journal Article] CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study.2015

    • Author(s)
      Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Yuanzhe L, Ogaki K, Ando M, Yoshinon H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
    • Journal Title

      Lancet Neurol

      Volume: 14 Issue: 3 Pages: 274-282

    • DOI

      10.1016/s1474-4422(14)70266-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24500868, KAKENHI-PROJECT-24790903, KAKENHI-PUBLICLY-25110720, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25713015, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10050, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-25257507, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-25305030
  • [Journal Article] High frequency of beta-propeller protein-associated neurodegeneration (BPAN) among patients with intellectual disability and young-onset parkinsonism.2015

    • Author(s)
      Nishioka K, Oyama G, Yoshino H, Li Y, Matsushima T, Takeuchi C, Mochizuki Y, Mori-Yoshimura M, Murata M, Yamasita C, Nakamura N, Konishi Y, Ohi K, Ichikawa K, Terada T, Obi T, Funayama M, Saiki S, Hattori N.
    • Journal Title

      Neurobiol Aging.

      Volume: S0197 Issue: 5 Pages: 54-58

    • DOI

      10.1016/j.neurobiolaging.2015.01.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-15K19498, KAKENHI-PROJECT-15H04842
  • [Journal Article] p150^<glued>-associated disorders are caused by activation of intrinsic apoptotic pathway2014

    • Author(s)
      Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, Kawajiri S, Sasaki H, Koike M, Tsuboi Y, Hattori N
    • Journal Title

      PLOS ONE

      Volume: 9

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway.2014

    • Author(s)
      Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, Kawajiri S, Sasaki H, Koike M, Tsuboi Y, Hattori N.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 4 Pages: e94645-e94645

    • DOI

      10.1371/journal.pone.0094645

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25860725, KAKENHI-PUBLICLY-26111519
  • [Journal Article] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease.2014

    • Author(s)
      Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, Imoto M
    • Journal Title

      PLOS ONE

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Journal Article] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease.2014

    • Author(s)
      Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, Imoto M
    • Journal Title

      PLOS ONE

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Regulation by mitophagy2014

    • Author(s)
      Hattori N, Saiki S, Imai Y.
    • Journal Title

      Int J Biochem Cell Biol.

      Volume: 53 Pages: 147-50

    • DOI

      10.1016/j.biocel.2014.05.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-26117727, KAKENHI-PROJECT-26293070
  • [Journal Article] p150glued-associated disorders are caused by activation of intrinsic apoptotic pathway.2014

    • Author(s)
      Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, Kawajiri S, Sasaki H, Koike M, Tsuboi Y, Hattori N
    • Journal Title

      PLOS ONE

      Volume: in press

    • NAID

      40020259609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] p150glued-associated disorders are caused by activation of intrinsic apoptotic pathway.2014

    • Author(s)
      Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, Kawajiri S, Sasaki H, Koike M, Tsuboi Y, Hattori N
    • Journal Title

      PLOS ONE

      Volume: in press

    • NAID

      40020259609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.2013

    • Author(s)
      Matsui H, Sato F, Sato S, Koike M, Taruno Y, Saiki S, Funayama M, Ito H, Taniguchi Y, Uemura N, Toyoda A, Sakaki Y, Takeda S, Uchiyama Y, Hattori N, Takahashi R.
    • Journal Title

      FEBS Lett

      Volume: 587(9) Issue: 9 Pages: 1316-1325

    • DOI

      10.1016/j.febslet.2013.02.046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002, KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23590244, KAKENHI-PROJECT-23689046, KAKENHI-PROJECT-23790238, KAKENHI-PROJECT-24300132, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24659435, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PUBLICLY-23129506
  • [Journal Article] ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons2013

    • Author(s)
      Matsui H, Sato F, Sato S, Koike M, Taruno Y, Saiki S, Funayama M, Ito H, Taniguchi Y, Uemura N, Toyoda A, Sakaki Y, Takeda S, Uchiyama Y, Hattori N, Takahashi R
    • Journal Title

      F EBS Lett

      Volume: 587 Pages: 1316-25

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Molecular pathogenesis of Parkinson disease : update2012

    • Author(s)
      Saiki S, Sato S, Hattori N
    • Journal Title

      J Neurol Neurosurg Psychiat

      Volume: 83 Pages: 430-6

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Molecular pathogenesis of Parkinson's disease : update2012

    • Author(s)
      Shinji Saiki, et al
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 83 Issue: 4 Pages: 430-436

    • DOI

      10.1136/jnnp-2011-301205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689046, KAKENHI-PROJECT-24659435, KAKENHI-PLANNED-23111003
  • [Journal Article] Mutations in the novel protein PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions2012

    • Author(s)
      Lee HY, Huang Y, Bruneau N, Roll P, Roberson EDO, Hermann M, Quinn E, Maas J, Edwards R, Ashizawa T, Baykan B, Bhatia K, Bressman S, Bruno MK, Brunt ER, Caraballo R, Echenne B, Fejerman N, Frucht S, Gurnett CA, Hirsch E, Houlden H, Jankovic J, Lee WL, Lynch DR, Mohamed S, Müller U, Nespeca MP, Renner D, Rochette J, Rudolf G, Saiki S, Soong BW, Swoboda KJ, Tucker S, Wood N, Hanna M, Bowcock A, Szepetowski P, Fu YH, Ptáček LJ
    • Journal Title

      Cell Reports

      Volume: 1 Pages: 2-12

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.2011

    • Author(s)
      Amo T, Sato S, Saiki S, Wolf AM, Toyomizu M, Gautier CA, Shen J, Ohta S, Hattori N.
    • Journal Title

      Neurobiology of Diseases

      Volume: 41 Pages: 111-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition2011

    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N
    • Journal Title

      Autophagy

      Volume: 7 Pages: 176-87

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.2011

    • Author(s)
      Amo T, Sato S, Saiki S, Wolf AM, Toyomizu M, Gautier CA, Shen J, Ohta S, Hattori N.
    • Journal Title

      Neurobiol Dis 41

      Pages: 111-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011

    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
    • Journal Title

      Autophagy 7

      Pages: 176-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects2011

    • Author(s)
      Amo T, Sato S, Saiki S, Wolf AM, Toyomizu M, Gautier CA, Shen J, Ohta S, Hattori N
    • Journal Title

      Neurobiol Dis

      Volume: 41 Pages: 111-8

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Genetic mutations and functions of PINK12011

    • Author(s)
      Kawajiri S, Saiki S, Sato S, Hattori N
    • Journal Title

      Trends Pharmacol Sci

      Volume: 32 Pages: 573-80

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Lysosomal positioning coordinates cellular nutrient responses2011

    • Author(s)
      Korolchuk V, Saiki S, Lichtenberg M, Siddiqi F, Roberts EA, Imarisio S, Jahreiss L, Sarkar S, Futter M, O'Kane CJ, Deretic V and Rubinsztein DC
    • Journal Title

      Nat Cell Biol

      Volume: 13 Pages: 453-60

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011

    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
    • Journal Title

      Autophagy

      Volume: 7 Pages: 176-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] DJ-1 associates with synaptic membranes2011

    • Author(s)
      Usami Y, Hatano T, Imai S, Kubo S, Sato S, Saiki S, Fujioka Y, Ohba Y, Sato F, Funayama M, Eguchi H, Shiba K, Ariga H, Shen J, Hattori N
    • Journal Title

      Neurobiol Dis

      Volume: 43 Pages: 651-62

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Journal Article] PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.2010

    • Author(s)
      Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K.
    • Journal Title

      J Cell Biol 189

      Pages: 211-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.2010

    • Author(s)
      Kawajiri S, Saiki S, Sato S, Sato F, Eguchi H, Hattori N
    • Journal Title

      FEBS Letters (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD.2010

    • Author(s)
      Kawajiri S, Machida Y, Saiki S, Sato S, Hattori N.
    • Journal Title

      Neuroscience Letters

      Volume: 481 Pages: 88-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.2010

    • Author(s)
      Kawajiri S, Saiki S, Sato S, Sato F, Eguchi H, Hattori N
    • Journal Title

      FEBS Letters

      Volume: 584 Pages: 1073-1079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD.2010

    • Author(s)
      Kawajiri S, Machida Y, Saiki S, Sato S, Hattori N.
    • Journal Title

      Neurosci Lett 481

      Pages: 88-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.2010

    • Author(s)
      Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K.
    • Journal Title

      Journal of Cell Biology

      Volume: 189 Pages: 211-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.2010

    • Author(s)
      Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N.
    • Journal Title

      FEBS Lett 584 Joint first authors

      Pages: 1073-1079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] p150glued-associated disorders are caused by activation of intrinsic apoptotic pathway

    • Author(s)
      Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, Kawajiri S, Sasaki H, Koike M, Tsuboi Y, Hattori N.
    • Journal Title

      PLOS ONE

      Volume: (in press)

    • NAID

      40020259609

    • Data Source
      KAKENHI-PROJECT-24659435
  • [Journal Article] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease

    • Author(s)
      Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N, Imoto M
    • Journal Title

      PLOS ONE

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23689046
  • [Patent] 化合物又はその塩、及びパーキンソン病治療薬又は予防薬2017

    • Inventor(s)
      井本正哉、斉木臣二、他
    • Industrial Property Rights Holder
      井本正哉、斉木臣二、他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Acquisition Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Patent] オートファジー誘導剤2017

    • Inventor(s)
      斉木臣二、他
    • Industrial Property Rights Holder
      斉木臣二、他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Patent] パーキンソン病診断指標2016

    • Inventor(s)
      服部信孝、斉木臣二、波田野琢、山城一雄、石川景一、他3名
    • Industrial Property Rights Holder
      学校法人順天堂
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-02-02
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Patent] パーキンソン病診断指標2016

    • Inventor(s)
      服部信孝、斉木臣二ら
    • Industrial Property Rights Holder
      服部信孝、斉木臣二ら
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-02-02
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Patent] パーキンソン病の重症度判定方法2016

    • Inventor(s)
      斉木臣二、他
    • Industrial Property Rights Holder
      斉木臣二、他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Patent] パーキンソン病の重症度判定方法2016

    • Inventor(s)
      服部信孝、斉木臣二ら
    • Industrial Property Rights Holder
      服部信孝、斉木臣二ら
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-10-27
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Patent] パーキンソン病の重症度判定方法2016

    • Inventor(s)
      斉木臣二 他
    • Industrial Property Rights Holder
      斉木臣二 他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Patent] パーキンソン病予防治療剤2013

    • Inventor(s)
      服部信孝、斉木臣二、井本正哉、藤 巻貴宏
    • Industrial Property Rights Holder
      学校法人順天堂
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Patent] パーキンソン病予防治療剤2013

    • Inventor(s)
      服部信孝、斉木臣二、井本正哉、藤巻貴宏
    • Industrial Property Rights Holder
      服部信孝、斉木臣二、井本正哉、藤巻貴宏
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Patent] パーキンソン病予防治療剤2013

    • Inventor(s)
      服部信孝、斉木臣二、井本正哉、藤巻貴宏
    • Industrial Property Rights Holder
      学校法人順天堂
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Patent] パーキンソン病予防治療剤2013

    • Inventor(s)
      服部信孝、斉木臣二、井本正哉、藤巻貴宏
    • Industrial Property Rights Holder
      服部信孝、斉木臣二、井本正哉、藤巻貴宏
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] Phosphorylated JIP4 mediates lysosomal clustering and autophagy in response to oxidative stress、口演2023

    • Author(s)
      笹澤有紀子、相馬早苗、三浦芳樹、鈴木絢未、橋本良太、伊達悠起、井本正哉、上野 隆、斉木臣二、服部信孝
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] A-synuclein aggregation and proteomics in Parkinson's disease and Multiple system atrophy, ポスター2023

    • Author(s)
      上野真一、波田野 琢、奥住文美、斉木臣二、小田吉哉、服部信孝
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] BRUP-1, a bilirubin modulator, showed neuroprotective activity. ポスター(英語)2022

    • Author(s)
      井本正哉、北浦哲志、笹澤有紀子、斉木臣二、服部信孝
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Causative gene finding for families with Parkinson's disease and Retinitis pigmentosa by whole exome sequencing.2021

    • Author(s)
      舩山学, 斉木臣二, 代田健祐, 吉野浩代, 李元哲, 西岡健弥, 服部信孝
    • Organizer
      日本人類遺伝学会第66回大会
    • Data Source
      KAKENHI-PROJECT-19K08003
  • [Presentation] バイオマーカー、パーキンソン病の血液成分におけるオミックス解析について(教育講演)2021

    • Author(s)
      斉木臣二
    • Organizer
      第14回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Identification of common molecular mechanism between Parkinson’s disease and Retinitis pigmentosa.2021

    • Author(s)
      舩山学,斉木臣二,吉野浩代,李元哲,西岡健弥,服部信孝
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K08003
  • [Presentation] New Biomarkers for Parkinson’s disease2019

    • Author(s)
      Shinji Saiki
    • Organizer
      6th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02744
  • [Presentation] Blood metabolic biomarkers for Parkinson's disease2019

    • Author(s)
      Shinji Saiki
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0027
  • [Presentation] New Biomarkers for Parkinson’s disease2019

    • Author(s)
      Shinji Saiki
    • Organizer
      6th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0027
  • [Presentation] パーキンソン病の代謝産物バイオマーカーについて2019

    • Author(s)
      斉木臣二
    • Organizer
      第13回パーキンソン病・運動障害疾患コングレス
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02744
  • [Presentation] Blood metabolic biomarkers for Parkinson's disease2019

    • Author(s)
      Shinji Saiki
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02744
  • [Presentation] パーキンソン病の代謝産物バイオマーカーについて2019

    • Author(s)
      斉木臣二
    • Organizer
      第13回パーキンソン病・運動障害疾患コングレス
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KT0027
  • [Presentation] Development of plasma metabolite biomarker for Parkinson’s disease2018

    • Author(s)
      Shinji Saiki
    • Organizer
      RIKEN Young Researcher Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] Metabolomics and Parkinson’s disease and related disorders2018

    • Author(s)
      Shinji Saiki
    • Organizer
      Takamatsu International Symposium for PD and MD in Tokyo
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] Serum polyamine metabolic changes in neurodegenerative diseases.2018

    • Author(s)
      Shinji Saiki
    • Organizer
      第59回日本神経学会総会
    • Data Source
      KAKENHI-PROJECT-18KT0027
  • [Presentation] Metabolomics and Parkinson’s disease and related disorders2018

    • Author(s)
      Shinji Saiki
    • Organizer
      Takamatsu International Symposium for PD and MD in Tokyo
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] バイオマーカーを指標とするパーキンソン病治療薬の探索とBET阻害剤JQ1による神経保護活性2018

    • Author(s)
      片浦哲志、斉木臣二、服部信孝、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会 第13回年会
    • Data Source
      KAKENHI-PROJECT-18H02099
  • [Presentation] Development of anti-Parkinson’s disease medicines focusing on autophagy/mitophagy modulation2018

    • Author(s)
      Shinji Saiki
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KT0027
  • [Presentation] Development of plasma metabolite biomarker for Parkinson’s disease2018

    • Author(s)
      Shinji Saiki
    • Organizer
      RIKEN Young Researcher Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Novel autophagy inducers against Parkinson Disease2018

    • Author(s)
      Shinji Saiki
    • Organizer
      The 8th International Symposium on Autophagy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] Development of anti-Parkinson’s disease medicines focusing on autophagy/mitophagy modulation2018

    • Author(s)
      Shinji Saiki
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02744
  • [Presentation] Biomarker-based Screening Identified BET inhibitor JQ1 as a Neuroprotective Compound for Parkinson’s Disease2018

    • Author(s)
      Tetsushi Kataura, Shinji Saiki, Nobutaka Hattori, Masaya Imoto
    • Organizer
      第9回日韓ケミカルバイオロジーシンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02099
  • [Presentation] Novel autophagy inducers against Parkinson Disease2018

    • Author(s)
      Shinji Saiki
    • Organizer
      The 8th International Symposium on Autophagy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] オートファジーを標的としたパーキンソン病治療薬開発2017

    • Author(s)
      斉木臣二
    • Organizer
      日経バイオテク プロフェッショナルセミナー
    • Place of Presentation
      Learning Square新橋
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] オートファジー制御によるパーキンソン病治療薬探索2017

    • Author(s)
      斉木臣二
    • Organizer
      オートファジー合同セミナー
    • Place of Presentation
      セレクトン福島
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] オートファジーを標的としたパーキンソン病治療薬開発2017

    • Author(s)
      斉木臣二
    • Organizer
      日経バイオテクプロフェッショナルセミナー
    • Place of Presentation
      Learning Square新橋(東京都・港区)
    • Year and Date
      2017-03-06
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] オートファジーを標的としたパーキンソン病治療薬開発2017

    • Author(s)
      斉木臣二
    • Organizer
      日経バイオテク プロフェッショナルセミナー
    • Place of Presentation
      Learning Square新橋
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] オートファジー制御によるパーキンソン病治療薬探索2017

    • Author(s)
      斉木臣二
    • Organizer
      日本学術振興会A3事業 日本オートファジー合同セミナー
    • Place of Presentation
      セレクトン福島
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Autophagy and mitophagy regulation by small chemicals2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine
    • Place of Presentation
      Shinagawa
    • Year and Date
      2016-10-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Blood biomarkers for Parkinson’s disease2016

    • Author(s)
      斉木臣二
    • Organizer
      第57回日本神経学会 Neuroscience Frontier Symposium
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2016-05-18
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] Drug development for Parkinson’s disease and autophagy2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 4th Sino-Japan Symposium on Autophagy
    • Place of Presentation
      Beijing
    • Year and Date
      2016-04-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] オートファジー調節による神経変性疾患の治療戦略2016

    • Author(s)
      斉木臣二
    • Organizer
      AMED難治性疾患実用化研究事業『筋萎縮性側索硬化症の新規治療法開発を目指した病態解明』平成28年度ワークショップ
    • Place of Presentation
      都市センターホテル(東京都・千代田区)
    • Year and Date
      2016-09-30
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] Autophagy and mitophagy regulation by small chemicals2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine
    • Place of Presentation
      Shinagawa
    • Year and Date
      2016-10-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] Drug development for Parkinson’s disease and autophagy2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 4th Sino-Japan Symposium on Autophagy,
    • Place of Presentation
      Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    • Year and Date
      2016-04-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Drug development for Parkinson’s disease and autophagy2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 4th Sino-Japan Symposium on Autophagy
    • Place of Presentation
      Beijing
    • Year and Date
      2016-04-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Drug development for Parkinson’s disease and autophagy2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 4th Sino-Japan Symposium on Autophagy
    • Place of Presentation
      Beijing (China)
    • Year and Date
      2016-04-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] Drug development for Parkinson's disease and autophagy2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 4th Sino-Japan Symposium on Autophagy
    • Place of Presentation
      Chinese Academy of Sciences, Beijing, China
    • Year and Date
      2016-04-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] オートファジー調節による神経変性疾患の治療戦略2016

    • Author(s)
      斉木臣二
    • Organizer
      AMED難治性疾患実用化研究事業『筋萎縮性側索硬化症の新規治療法開発を目指した病態解明』平成28年度ワークショップ
    • Place of Presentation
      東京都市センターホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] The role of microglia in the pathogenesis of Parkinson’s disease2016

    • Author(s)
      斉木臣二
    • Organizer
      第41回日本微小循環学会
    • Place of Presentation
      コクヨホール(東京都・港区)
    • Year and Date
      2016-09-23
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] Blood biomarkers for Parkinson’s disease2016

    • Author(s)
      Shinji Saiki
    • Organizer
      第57回日本神経学会
    • Place of Presentation
      神戸国際会館、神戸市、兵庫県
    • Year and Date
      2016-05-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] オートファジー調節による神経変性疾患の治療戦略2016

    • Author(s)
      斉木臣二
    • Organizer
      AMED難治性疾患実用化研究事業『筋萎縮性側索硬化症の新規治療法開発を目指した病態解明』平成28年度ワークショップ
    • Place of Presentation
      東京都市センターホテル
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Blood biomarkers for Parkinson’s disease2016

    • Author(s)
      Shinji Saiki
    • Organizer
      第57回日本神経学会
    • Place of Presentation
      神戸国際会議場、神戸市、兵庫県
    • Year and Date
      2016-05-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Autophagy and mitophagy regulation by small chemicals2016

    • Author(s)
      Shinji Saiki
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine
    • Place of Presentation
      TKP Garden City Shinagawa(東京都・港区)
    • Year and Date
      2016-10-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] パーキンソン病分子病態解析に基づくオートファジー促進小分子化合物の同定2015

    • Author(s)
      斉木臣二
    • Organizer
      第9回オートファジー研究会
    • Place of Presentation
      淡路夢舞台国際会議場、淡路市、兵庫県
    • Year and Date
      2015-11-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] パーキンソン病分子病態解析に基づくオートファジー促進小分子化合物の同定2015

    • Author(s)
      斉木臣二
    • Organizer
      第9回オートファジー研究会
    • Place of Presentation
      淡路夢舞台国際会議場、淡路市、兵庫県
    • Year and Date
      2015-11-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for parkinson's disease2015

    • Author(s)
      M.Imoto, T.Fujimaki, S.Saiki, E.Tashiro, D.Yamada, N.Hattori
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル(米国)
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116
  • [Presentation] Plasma Biomarkers for Parkinson’s disease.2015

    • Author(s)
      Shinji Saiki
    • Organizer
      XXI World Congress on Parkinson’s disease and related disorders
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2015-12-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] Plasma Biomarkers for Parkinson’s disease.2015

    • Author(s)
      Shinji Saiki
    • Organizer
      XXI World Congress on Parkinson’s disease and related disorders.
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2015-12-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] Plasma Biomarkers for Parkinson’s disease.2015

    • Author(s)
      Shinji Saiki
    • Organizer
      XXI World Congress on Parkinson’s disease and related disorders
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2015-12-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04843
  • [Presentation] パーキンソン病とオートファジー2014

    • Author(s)
      斉木臣二
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] ペリー症候群の分子病態とアポトーシスの関係2014

    • Author(s)
      石川景一, 斉木臣二, 古屋徳彦, 山田大介, 今道洋子, 李元哲, 河尻澄宏, 佐々木寛典, 小池正人, 坪井義夫,服部信孝
    • Organizer
      カテコールアミンと神経疾患研究会 2014
    • Place of Presentation
      東京
    • Year and Date
      2014-04-19
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] オートファジー調節作用を持つ薬剤の探索 -既存薬ライブラリーを用いて-2014

    • Author(s)
      平野一興、斉木臣二、古屋徳彦、山田大介、石川景一、佐谷秀行、服部信孝
    • Organizer
      厚生労働科学研究委託事業 難治性疾患等克服研究事業 「パーキンソン病患者由来iPS細胞を中心とする多面的疾患モデルに立脚した革新的医薬品の開発」 第2回班会議
    • Place of Presentation
      順天堂大学10号館1階会議室、東京
    • Year and Date
      2014-12-18
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] パーキンソン病と慢性炎症2014

    • Author(s)
      斉木臣二
    • Organizer
      第55回日本神経学会総会
    • Place of Presentation
      福岡国際会議場等
    • Invited
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] パーキンソン病と慢性炎症2014

    • Author(s)
      斉木臣二
    • Organizer
      第55回日本神経学会総会
    • Place of Presentation
      福岡国際会議場等福岡県
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病と慢性炎症2014

    • Author(s)
      斉木臣二
    • Organizer
      第55回日本神経学会総会
    • Place of Presentation
      福岡国際会議場等
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病と慢性炎症2014

    • Author(s)
      斉木臣二
    • Organizer
      第55回日本神経学会総会
    • Place of Presentation
      福岡国際会議場等福岡県
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] ペリー症候群の分子病態とアポトーシスの関係2014

    • Author(s)
      石川景一, 斉木臣二, 古屋徳彦, 山田大介, 今道洋子, 李元哲, 河尻澄宏, 佐々木寛典, 小池正人, 坪井義夫,服部信孝
    • Organizer
      カテコールアミンと神経疾患研究会 2014
    • Place of Presentation
      品川プリンスホテル
    • Year and Date
      2014-04-19
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] パーキンソン病の臨床と創薬-オートファジーとの関連を中心に-2013

    • Author(s)
      斉木臣二
    • Organizer
      第33回ゲノム創薬フォーラム
    • Place of Presentation
      東京大学医科学研究所東京都
    • Year and Date
      2013-07-25
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] パーキンソン病病態とオートファジーの関連について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金 新学術領域 細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病の臨床と創薬-オートファジーとの関連を中心に-2013

    • Author(s)
      斉木臣二
    • Organizer
      第33回ゲノム創薬フォーラム
    • Place of Presentation
      東京大学医科学研究所東京都
    • Year and Date
      2013-07-24
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] オートファジーを標的としたパーキンソン病治療について2013

    • Author(s)
      斉木臣二
    • Organizer
      第7回オートファジー研究会
    • Place of Presentation
      静岡県掛川市
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] オートファジーを標的としたパーキンソン病治療について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金新学術領域オートファジーの集学的研究シンポジウム・オートファジー研究会
    • Place of Presentation
      ヤマハリゾート嬬恋静岡県
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病病態とオートファジーの関連について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金新学術領域細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場兵庫県
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] オートファジーを標的としたパーキンソン病治療について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金 新学術領域 オートファジーの集学的研究・オートファジー研究会
    • Place of Presentation
      ヤマハ嬬恋リゾート
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病病態とオートファジーの関連について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金新学術領域細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場兵庫県
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病病態とオートファジーの関連について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金 新学術領域 細胞内ロジスティクスシンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場
    • Invited
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] オートファジーを標的としたパーキンソン病治療について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金 新学術領域 オートファジーの集学的研究シンポジウム・オートファジー研究会
    • Place of Presentation
      ヤマハリゾート嬬恋
    • Invited
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] パーキンソン病の臨床と創薬 -オートファジーとの関連を中心に-2013

    • Author(s)
      斉木臣二
    • Organizer
      第33回ゲノム創薬フォーラム
    • Place of Presentation
      東京大学医科学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] パーキンソン病病態とオートファジーの関連について2013

    • Author(s)
      斉木臣二
    • Organizer
      細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      兵庫県淡路市
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] パーキンソン病の臨床と創薬 -オートファジーとの関連を中心に-2013

    • Author(s)
      斉木臣二
    • Organizer
      第33回ゲノム創薬フォーラム
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2013-07-25
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] オートファジーを標的としたパーキンソン病治療について2013

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省科学研究費補助金新学術領域オートファジーの集学的研究シンポジウム・オートファジー研究会
    • Place of Presentation
      ヤマハリゾート嬬恋静岡県
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] Autophagic regulation by caffeine and its analogues.2011

    • Author(s)
      斉木臣二
    • Organizer
      オートファジー研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Year and Date
      2011-01-14
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] EFFECTS OF CAFFEINE AND CAFFEINE ANALOGUES ON AUTOP HAGY IN CULTURED CELLS2011

    • Author(s)
      Shinji Saiki, 他
    • Organizer
      Autophagy in health and Disease (EMBO conference)
    • Place of Presentation
      Israel
    • Year and Date
      2011-10-30
    • Data Source
      KAKENHI-PROJECT-23689046
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] Analysis of whether MITOL associates with the PINK1/parkin-mediated mitophagy.2010

    • Author(s)
      Sumihiro Kawajiri, Shinji Saiki, Shigeto Sato, Shigeru Yanagi, Nobutaka Hattori.
    • Organizer
      The 7th Conference of Asian Society for Mitochondrial Research and Medicine (ASMRM) and 10th Conference of Japanese Society for Mitochondrial Research and Medicine (J-mit)
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第52回日本神経学会
    • Place of Presentation
      東京(東京国際フォーラム)
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] Caffeine regulates autophagy via mTOR signaling pathway.2010

    • Author(s)
      斉木臣二、今道洋子、河尻澄宏、服部信孝
    • Organizer
      第5回日本ケミカルバイオロジー学会
    • Place of Presentation
      慶応義塾大学日吉キャンパス協生館
    • Year and Date
      2010-05-18
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第18回カテコールアミン研究会
    • Place of Presentation
      品川プリンホテル
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] PINK1, parkin, mitochondriaの相互作用の検討2010

    • Author(s)
      斉木臣二、河尻澄宏、佐藤栄人、今道洋子、服部信孝
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第18回カテコールアミン研究会
    • Place of Presentation
      東京(品川プリンスホテル)
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] PINK1, parkin, mitochondriaの相互作用の検討2010

    • Author(s)
      斉木臣二, 河尻澄宏、佐藤栄人、今道洋子、服部信孝
    • Organizer
      第52回日本神経学会
    • Place of Presentation
      東京(東京国際フォーラム)
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] PINK1の分解機構の解析2009

    • Author(s)
      河尻澄宏、斉木臣二, ら
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] オートファジーとパーキンソン病病態

    • Author(s)
      斉木臣二
    • Organizer
      第45回(2015)新潟神経学夏期セミナー
    • Place of Presentation
      新潟大学脳研究所統合脳機能研究センター
    • Year and Date
      2015-07-23 – 2015-07-25
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] 抗結核薬エタンブトールのオートファジー阻害作用

    • Author(s)
      山田大介, 斉木臣二, 古屋徳彦, 石川景一, 今道洋子, 神戸大朋, 藤村 務, 上野隆, 小池正人, 服部信孝
    • Organizer
      第8回オートファジー研究会
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ北海道、札幌
    • Year and Date
      2014-11-09 – 2014-11-12
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] パーキンソン病と慢性炎症

    • Author(s)
      斉木臣二
    • Organizer
      第55回日本神経学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-21 – 2014-05-24
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] パーキンソン病の臨床と創薬 -オートファジーとの関連を中心に-

    • Author(s)
      斉木臣二
    • Organizer
      第33回ゲノム創薬フォーラム
    • Place of Presentation
      東京大学医科学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659435
  • [Presentation] パーキンソン病とオートファジー

    • Author(s)
      斉木臣二
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] パーキンソン病とオートファジー

    • Author(s)
      斉木臣二
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館、京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] パーキンソン病の臨床と創薬 -オートファジーとの関連を中心に-

    • Author(s)
      斉木臣二
    • Organizer
      第33回ゲノム創薬フォーラム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
  • [Presentation] PINK1/parkin-mediated mitophagy and apoptosis.

    • Author(s)
      Shinji Saiki
    • Organizer
      第16回北東アジアシンポジウム
    • Place of Presentation
      Westin Chosun Hotel、釜山、韓国
    • Year and Date
      2014-12-18 – 2014-12-20
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] パーキンソン病と慢性炎症

    • Author(s)
      斉木臣二
    • Organizer
      第55回日本神経学会総会 シンポジウム31
    • Place of Presentation
      福岡国際会議場等
    • Year and Date
      2014-05-21 – 2014-05-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] PD患者におけるオートファジー関連BM同定の試み

    • Author(s)
      斉木臣二
    • Organizer
      第8回オートファジー研究会
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ北海道、札幌
    • Year and Date
      2014-11-09 – 2014-11-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] オートファジーを標的としたパーキンソン病治療について

    • Author(s)
      斉木臣二
    • Organizer
      第7回オートファジー研究会
    • Place of Presentation
      ヤマハリゾート嬬恋 静岡県
    • Year and Date
      2013-12-19 – 2013-12-21
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] パーキンソン病病態とオートファジーの関連について

    • Author(s)
      斉木臣二
    • Organizer
      文部科学省新学術領域「細胞内ロジスティクス」シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場
    • Year and Date
      2013-09-17 – 2013-09-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-25111007
  • [Presentation] PINK1/parkin-mediated mitophagy and apoptosis

    • Author(s)
      Shinji Saiki
    • Organizer
      第16回北東アジアシンポジウム
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2014-12-18 – 2014-12-20
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25111001
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