AOKI Motokuni 青木元邦

… Alternative Names

青木元邦アオキモトクニ

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Researcher Number	00346214
Affiliation (Current)	2025: 森ノ宮医療大学, 保健医療学研究科, 教授
Affiliation (based on the past Project Information) *help	2010 – 2021: 森ノ宮医療大学, 保健医療学部, 教授 2003 – 2005: 大阪大学, 医学系研究科, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) Except Principal Investigator General internal medicine (including Psychosomatic medicine) / Basic Section 52010:General internal medicine-related / Cardiovascular surgery / Biological Sciences / Kidney internal medicine / Circulatory organs internal medicine
Keywords	Principal Investigator ets / NFkB / 軟骨細胞 / レニンーアンジオテンシン系 / Atherosclerosis / Restenosis / Graft failure / Aneurysm / Decoy oligonucleotides / Molecular therapy … More / J-PRAN / MMP / 大動脈瘤 / キメラデコイ / 動脈硬化 / 再狭窄 / グラフト不全 / 動脈瘤 / デコイ / 分子治療 / アンジョテンシン受容体拮抗薬 / アンジオテンシン受容体拮抗薬 / 軟骨代謝 / アポトーシス / 軟骨変性 / 軟骨細胞代謝 / 変形性関節症 / 高血圧 / アンジオテンシン受容体拮抗剤 / アンジオテンシンII / 老年医学 / 骨折修復 / 骨芽細胞 / ARB / RA系 / アンジオテンシンII受容体拮抗薬 / 骨リモデリング / 骨粗鬆症 … More Except Principal Investigator HIF1-α / HIF-1 / 線維化 / 関節拘縮 / NFkB / 遺伝子治療 / 核酸医薬 / アンギオテンシン II / NF-kB / HIF-1α / アンギオテンシンII / レニン・アンギオテンシン系 / アンギオテンシンII （AngII） / レニン・アンギオテンシン（RA）系 / Ang II 1型受容体(AT1R) / アンギオテンシンII (AngII) / レニン・アンギオテンシン(RA)系 / 滑膜組織 / 腹部大動脈瘤 / stentgraft / decoy型核酸医薬 / stent graft / 分子治療製剤 / 血管内治療 / ステントグラフト / 大動脈瘤 / HIF1α / ＣＴＧＦ / HIF / VEGF / CTGF / デコイ核酸医薬 / 滑膜 / サイトカイン / 転写因子 / 炎症 / 東洋医学 / 内科学一般 / マクロファージ / 炎症性サイトカイン / 創傷治癒 / 筋肉再生 / 炎症性腸疾患 / 鍼灸刺激 / 東洋医療 / 神経細胞保護効果 / 肝細胞増殖因子 / パーキンソン病 / HVJ-liposome法 / 分子治療 / HVJ-envelope法 / 食塩感受性高血圧モデルラット / NKCC2遺伝子 / TSC遺伝子 / 高血圧 / HGF / 血管内皮細胞 / 血管新生因子 / 細胞外基質 / 細胞移植 / 虚血性心血管病 / 血管内皮 / 胚性幹細胞 Less

Role of the RA system in disuse joint contracture: a new strategy to maintain ADLs in the elderly
- Principal Investigator
  
  Kawahata Hirohisa
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Morinomiya University of Medical Sciences
Endovascular treatment with oligonucleotide therapeutics for aortic aneurysm
- Principal Investigator
  
  SHIRAYA Suguru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Tottori University
Angiotensin II Modulates Hypertrophic Differentiation and Apoptosis of Chondrocytes: Relationship of hypertension to OsteoarthrosisPrincipal Investigator
- Principal Investigator
  
  Aoki Motokuni
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
Elucidation of the molecular mechanisms that the axis of the HIF-1 in the joint contracture: the development of new molecular therapeutic formulation
- Principal Investigator
  
  KAWAHATA Hirohisa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
Role of RAS in bone remodeling and protective effect of ARB on bone densityPrincipal Investigator
- Principal Investigator
  
  AOKI Motokuni
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
Effect of acupuncture on the molecular mechanism of inflammation via transcription factor, NFkB.
- Principal Investigator
  
  MATSUKUMA Hideaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
肝細胞増殖因子(HGF)遺伝子を用いたパーキンソン病に対する遺伝子治療の検討
- Principal Investigator
  
  森下竜一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Naチャンネル制御遺伝子導入システムによる高血圧症に対する革新的分子治療法の開発
- Principal Investigator
  
  OGIHARA Toshio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
胚性幹細砲を用いた、心血管発生機構の解明、ならびに難治性心血管病における組織再生
- Principal Investigator
  
  MORISHITA Ryuichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
The development of molecular therapy using decoy oligonucleotides : for clinical applications.Principal Investigator
- Principal Investigator
  
  AOKI Motokuni
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University

All 2015 2014 2013 2012 2005 Other

All Journal Article Presentation Book

[Book] 高血圧の遺伝子治療と再生医学2005
- Author(s)
  青木元邦, 荻原俊男
- Publisher
  日医雑誌
- Data Source
  KAKENHI-PROJECT-16659224
[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse2015
- Author(s)
  Kawahata H, Sotobayashi D, Aoki M, Shimizu H, Nakagami H, Ogihara T, Morishita R.
- Journal Title
  
  Hypertension Research
  
  Volume: 38(6) Issue: 6 Pages: 382-393
- DOI
  10.1038/hr.2015.18
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460928
[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse.2015
- Author(s)
  Kawahata H, Sotobayashi D, Aoki M, Shimizu H, Nakagami H, Ogihara T, Morishita R.
- Journal Title
  
  Ｈｙｐｅｒｔｅｎｓｉｏｎ　Ｒｅｓｅａｒｃｈ
  
  Volume: 19
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460928
[Journal Article] Anti-inflammatory effect of electro-acupuncture via rduction in clonic pristalsis in a mouse model of inflammatory bowel disease.2013
- Author(s)
  Yutani T, Kawahata H, Sotobayashi D, Kawanami H, Matsukuma H, Aoki M.
- Journal Title
  
  Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry.
  
  Volume: 13(2) Issue: 2 Pages: 122-131
- DOI
  10.2174/1871522211313020006
- Data Source
  KAKENHI-PROJECT-22590670
[Journal Article] 関節拘縮における滑膜の分子生物学的変化とLIPUSによる治療介入の検討2012
- Author(s)
  外林大輔,川畑浩久,吉川徹,穴田夏希,細田明菜,根來信也,青木元邦
- Journal Title
  
  兵庫学術誌
  
  Volume: 38号 Pages: 87-94
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] Effect of angiotensin II on differentiation and apoptosis of chondrocytes in cartilage formation in the process of fracture healing2015
- Author(s)
  26.Hirohisa Kawahata, Motokuni Aoki, Ryuichi Morishita, Toshio Ogihara
- Organizer
  11th Asia Pacific Congress of Hypertension
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2015-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460928
[Presentation] レニンーアンジオテンシン系が骨形成系・軟骨細胞分化・骨折修復過程に及ぼす影響についての検討2014
- Author(s)
  川畑浩久、青木元邦
- Organizer
  日本抗加齢医学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-26460928
[Presentation] 腸炎モデルマウスに対する鍼刺激の影響-炎症性腸疾患への補完医療確立に向けて-2013
- Author(s)
  湯谷達、川畑浩久、青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2013-06-09
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] 灸刺激が創傷治癒過程に与える影響2013
- Author(s)
  川波博、湯谷達、川畑浩久、青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2013-06-09
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] レニン―アンジオテンシン系が骨折修復過程に与える影響についての検討2013
- Author(s)
  青木元邦,川畑浩久,森下竜,荻原俊男
- Organizer
  第55回日本老年医学会
- Place of Presentation
  大阪国際会議場．大阪
- Data Source
  KAKENHI-PROJECT-23590902
[Presentation] 腸炎モデルマウスに対する鍼刺激の影響－炎症性腸疾患への補完医療確立に向けて－2013
- Author(s)
  青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] 関節拘縮における関節内病変についての組織学的・分子生物学的検討2013
- Author(s)
  川畑浩久、青木元邦、森下竜一、荻原俊男
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] レニンーアンジオテンシン系が骨折修復過程に与える影響についての検討2013
- Author(s)
  青木元邦、川畑浩久、荻原俊男
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-06
- Data Source
  KAKENHI-PROJECT-23590902
[Presentation] 高齢者高血圧患者におけるアンジオテンシン受容体拮抗薬による骨密度減少の抑制効果2012
- Author(s)
  青木元邦、湯久浩、守口篤、志水秀朗、中神啓徳、荻原俊男、森下竜一
- Organizer
  日本高血圧学会第一回臨床高血圧フォーラム
- Place of Presentation
  大阪
- Year and Date
  2012-05-12
- Data Source
  KAKENHI-PROJECT-23590902
[Presentation] 腸炎モデルマウスに対する鍼刺激の影響-炎症性腸疾患への補完医療確立に向けて-2012
- Author(s)
  湯谷達、浅野真里絵、川畑浩久、青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  三重
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] 関節拘縮の進展メカニズムに関する検討2012
- Author(s)
  青木元邦,外林大輔,川畑浩久
- Organizer
  第12回日本抗加齢医学会総会
- Place of Presentation
  神奈川パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] 腸炎モデルマウスに対する鍼刺激の影響－炎症性腸疾患への補完医療確立に向けて－2012
- Author(s)
  青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  三重
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] 関節拘縮の分子メカニズム解明と新規分子治療製剤の開発
- Author(s)
  青木元邦
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-06-06 – 2014-06-08
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] 高齢者高血圧患者におけるアンジオテンシン受容体拮抗薬による骨密度減少の抑制効果
- Author(s)
  青木元邦
- Organizer
  高血圧フォーラム
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23590902

1. KAWAHATA Hirohisa (30454680)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. MORISHITA Ryuichi (40291439)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. OGIHARA Toshio (60107042)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. HIRONORI Nakagami (20325369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 林真一郎 (20396740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MATSUKUMA Hideaki (70518638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SHIRAYA Suguru (20601933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中村嘉伸 (80335538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西村元延 (90291442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AOKI Motokuni 青木 元邦

青木 元邦 アオキ モトクニ

Research Projects

Research Products

Co-Researchers

Role of the RA system in disuse joint contracture: a new strategy to maintain ADLs in the elderly

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Endovascular treatment with oligonucleotide therapeutics for aortic aneurysm

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Angiotensin II Modulates Hypertrophic Differentiation and Apoptosis of Chondrocytes: Relationship of hypertension to OsteoarthrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular mechanisms that the axis of the HIF-1 in the joint contracture: the development of new molecular therapeutic formulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of RAS in bone remodeling and protective effect of ARB on bone densityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of acupuncture on the molecular mechanism of inflammation via transcription factor, NFkB.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝細胞増殖因子(HGF)遺伝子を用いたパーキンソン病に対する遺伝子治療の検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Naチャンネル制御遺伝子導入システムによる高血圧症に対する革新的分子治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性幹細砲を用いた、心血管発生機構の解明、ならびに難治性心血管病における組織再生

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of molecular therapy using decoy oligonucleotides : for clinical applications.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 高血圧の遺伝子治療と再生医学2005

Author(s)

Publisher

Data Source

[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse.2015

Author(s)

Journal Title

Data Source

[Journal Article] Anti-inflammatory effect of electro-acupuncture via rduction in clonic pristalsis in a mouse model of inflammatory bowel disease.2013

Author(s)

AOKI Motokuni 青木元邦

青木元邦アオキモトクニ