NARUISHI Koji 成石浩司

Researcher Number	00346446
Affiliation *help	2016 – 2017 : 徳島大学, 病院, 講師 2015 : 徳島大学, 大学病院, 講師 2010 – 2012 : 岩手医科大学, 歯学部, 准教授 2012 : 岩手医科大学, 歯学部, 歯学部 2009 – 2010 : 岡山大学, 大学病院, 講師 … More
Research Field	Principal Investigator Periodontal dentistry Except Principal Investigator Periodontal dentistry / Periodontology / Conservative dentistry / Respiratory organ internal medicine / Periodontal dentistry
Keywords	Principal Investigator 糖尿病 / MMP-3 / 歯肉線維芽細胞 / 遺伝子マイクロアレイ解析 / 歯周病悪化メカニズム Except Principal Investigator 歯周病 / 遺伝子導入 / インターロイキン6 / 歯肉線維芽細胞 / 糖尿病 … More

人工細胞を用いたオーラルケアシステムの基礎研究Ongoing
- Principal Investigator
  
  木戸淳一
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
糖尿病関連歯周炎のIL-6動態に着目したマクロファージ・線維芽細胞クロストークPrincipal InvestigatorOngoing
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
最終糖化産物AGEsによる糖尿病関連歯周炎の重症化機序の解明と診断システムの構築Ongoing
- Principal Investigator
  
  NAGATA Toshihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
最終糖化産物とインフラマソームの関連から探る糖尿病関連歯周炎の病態Ongoing
- Principal Investigator
  
  板東美香
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
細胞性バイオマーカーを用いたインプラント疾患の診断とデバイス開発Ongoing
- Principal Investigator
  
  木戸淳一
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
ＡＰ－１によるカテプシン産生制御に着目した歯肉増殖症・歯周病診断の新機軸Principal Investigator
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Iwate Medical University
How periodontitis can affect prostate cancer metastasis?
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Chronic infection and immune response in COPD patients
- Principal Investigator
  
  MURO Shigeo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Healing mechanism of rat experimental periapical lesions targeting laminin γ2 expression
- Principal Investigator
  
  HATANAKA Kazu, ARAI Hideo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Possible Mechanisms of Progression of Periodontits by MMP-3 in Diabetic PatientsPrincipal Investigator
- Principal Investigator
  
  NARUISHI Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Investigation of the mechanisms of osteogenic differentiation by RhoA in periodontal ligament cells for cell transplantation
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
New bactericide delivery system for oral care
- Principal Investigator
  
  TANIMOTO Ichiro, 松浦香織
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Mail Medicine using Fingertip Plasma for Screening and Monitoring Periodontitis
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
糖尿病患者の歯周病悪化を誘発する新規因子の網羅的な解析および同定Principal Investigator
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
The effect on dentin-pulp complex by FIP-2 isolated from rat wounded pulp
- Principal Investigator
  
  ARAI Hideo, 明貝文夫
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Study for oral infectious control during peripheral blood stem cell transplantation
- Principal Investigator
  
  TANIMOTO Ichiro, 澤田聡子
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University

All 2016 2015 2013 2011 2010 2009 2008 2006 Other

All Journal Article Presentation

[Journal Article] YKL-40 level in gingival crevicular fluid from patients with periodontitis and type 2 diabetes2015
- Author(s)
  Kido J, Bando Y, Bando M, Kajiura Y, Hiroshima Y, Inagaki Y, Murata H, Ikuta T, Kido R, Naruishi K, Funaki M, Nagata T.
- Journal Title
  
  Oral Diseases
  
  Volume : 21 Pages : 667-673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253104, KAKENHI-PROJECT-15H05054
[Journal Article] 肥満糖尿病ラット歯周炎の歯肉組織におけるオステオポンチンの局在2015
- Author(s)
  稲垣裕司、中島由紀子、堀部ますみ、生田貴久、梶浦由加里、成石浩司、木戸淳一、永田俊彦
- Journal Title
  
  日本歯周病学会会誌
  
  Volume : 57 Pages : 149-158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05054
[Journal Article] Secreted caveolin-1 enhances periodontal inflammation by targeting gingival fibroblasts2013
- Author(s)
  Takizawa N, Sawada S, Chosa N, Ishisaki A, Naruishi K
- Journal Title
  
  Biomed Res
  
  Volume : 34(1) Pages : 1-11
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] Cathepsin B, D, and L Regulation in Cyclosporin A-mediated Gingival Hyperplasia of a Patient with Sarcoidosis.2011
- Author(s)
  Osamu Murai, Koji Naruishi, Satoshi Ogihara, Nagisa Suwa, Satomi Kanazawa, Takashi Yaegashi, Yasunori Takeda, Kazushi Kunimatsu
- Journal Title
  
  Clin.Lab. in Press
- Data Source
  KAKENHI-PROJECT-20592428
[Journal Article] Naruishi K, Omori K, Maeda H, Sonoi N, Funakoshi K, Hirai K, Ishii M, Kubo K, Kobayashi H, Tomiyama T, Yamamoto D, Tanimoto I,Kunimatsu K, and Takashiba S2011
- Author(s)
  Naruishi K, Omori K, Maeda H, Sonoi N, Funakoshi K, Hirai K, Ishii M, Kubo K, Kobayashi H, Tomiyama T, Yamamoto D, Tanimoto I,Kunimatsu K, and Takashiba S
- Journal Title
  
  J Biol Regul Homeost Agents
  
  Volume : 25(2) Pages : 195-202
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] 医科歯科連携医療における歯周病原細菌に対する血清IgG抗体価検査の導入2011
- Author(s)
  村井治, 成石浩司, 佐々木大輔, 大川義人, 八重柏隆, 國松和司
- Journal Title
  
  日本口腔検査学会雑誌第3巻1号
  
  Pages : 36-41
- Data Source
  KAKENHI-PROJECT-20592428
[Journal Article] Immune responses to porphyromonas gingivalis infection suppress systemic inflammatory response in experimental murine model2011
- Author(s)
  Naruishi, Koji
- Journal Title
  
  Journal of biological regulators and homeostatic agents
  
  Volume : 25 Pages : 195-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] IL-6/sIL-6R enhances cathepsin B and L production via caveolin-1-mediated JNK-AP-1 pathway in human gingival fibroblasts.2008
- Author(s)
  Yamaguchi T, Naruishi K, Arai H, Nishimura F, Takashiba s.
- Journal Title
  
  Journal of Cellular Physiology 217
  
  Pages : 423-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592428
[Journal Article] 高血糖状態で培養したヒト歯肉線維芽細胞の網羅的な遺伝子解析2006
- Author(s)
  成石浩司ら
- Journal Title
  
  第20回日本顎頭蓋機能学会記念学術大会抄録集 20巻・1号
  
  Pages : 19-19
- Data Source
  KAKENHI-PROJECT-18791592
[Journal Article] Porphyromonas gingivalis fimbriae-dependent interleukin-6 autocrine regulation by increase of gp130 in endothelial cells
- Author(s)
  Y-S. Ho, M-T. Lai, S-J. Liu, C-T. Lin, K. Naruishi, S. Takashiba, H-H. Chou
- Journal Title
  
  Journal of Periodontal Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] High glucose enhances P. gingivalis-induced ctokine production in THP-1 monocytes2016
- Author(s)
  Kajiura Y, Naruishi K, Nakajima Y, Nishikawa Y, Lwe JH, Kido J, Nagata T
- Organizer
  94th General Session of the IADR
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2016-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] カロテノイドは高グルコース下で培養したヒト歯肉線維芽細胞のIL-6誘導性蛋白分解酵素産生を抑制する2016
- Author(s)
  Lew Jung-Hwan，成石浩司，梶浦由加里，西川泰史，木戸淳一，永田俊彦
- Organizer
  第59回春季日本歯周病学会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] 最終糖化産物は口腔上皮細胞の遺伝子発現を調節する2015
- Author(s)
  坂本英次郎、木戸淳一、梶浦由加里、板東美香、稲垣裕司、成石浩司、生田貴久、永田俊彦
- Organizer
  第58回秋季日本歯周病学会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] 高血糖状態で培養したヒト歯肉線維芽細胞の網羅的な遺伝子解析2011
- Author(s)
  澤田俊輔, 成石浩司
- Organizer
  岩手医科大学歯学会第72回例会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯周疾患を標的とした臨床研究と細胞生物学的アプローチ2010
- Author(s)
  成石浩司
- Organizer
  第70回岩手医科大学歯学会例会
- Place of Presentation
  盛岡特別講演
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Inhibition of IL-6/sIL-6R-induced VEGF production by sgp130 in gingival fibroblasts.2010
- Author(s)
  山口知子, 成石浩司, 大森一弘, 前田博史, 高柴正悟
- Organizer
  88th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Evaluation of Periodontitis by a Blood Test.2010
- Author(s)
  高柴正悟, 工藤値英子, 成石浩司, 前田博史
- Organizer
  88th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] nrdD様遺伝子の存在は血中移行したPorphyromonas gingivalisの病原性を決定する2010
- Author(s)
  園井教裕, 前田博史, 成石浩司, 苔口進, 大森一弘, 石井真由美, 平井公人, 山部こころ, 谷本一郎, 高柴正悟
- Organizer
  第53回日本歯周病学会秋期学術大会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 塗布用ブラシ一体型一般用歯周病薬がSPT期患者の歯肉溝滲出液中サイトカイン量に与える影響2010
- Author(s)
  安田多賀子, 成石浩司, 犬伏順也, 畑中加珠, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会秋期学術大会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 「歯周組織への感染とそれに対する免疫応答の特異性とは?」歯周病態における体液性免疫応答の成立と意義-IgG抗体産生性に着目して-2010
- Author(s)
  成石浩司
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡シンポジウム
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] MMP-3によるヒト単球系細胞株THP-1からの可溶型IL-6受容体の産生亢進2010
- Author(s)
  小林寛也, 大森一弘, 成石浩司, 山口知子, 冨山高史, 久保克行, 前田博史, 高柴正悟
- Organizer
  第132回日本歯科保存学会春期学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 企業内定期健康診断における歯周病原細菌に対する血清IgG抗体価検査を用いた歯周病スクリーニング効果の統計学的検討2010
- Author(s)
  工藤値英子, 成石浩司, 三橋千代子, 米田哲, 永田俊彦, 佐藤勉, 前田博, 高柴正悟
- Organizer
  第132回日本歯科保存学会春期学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 塗布用ブラシ一体型歯周病薬によるプラークコントロールがSPT期の歯周組織の病状安定に与える影響2010
- Author(s)
  犬伏順也, 安田多賀子, 西田美恵子, 畑中加珠, 成石浩司, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] IL-6によるヒト歯髄細胞のVEGF産生誘導2010
- Author(s)
  藤原英明, 成石浩司, 澤田俊輔, 伊東俊太郎, 八重柏隆, 國松和司
- Organizer
  第133回日本歯科保存学会秋期学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 「間葉系幹細胞による歯髄・歯周再生医療の現状と展望～免疫と組織再生の観点から～」歯周組織におけるサイトカインネットワークと再生への展開2010
- Author(s)
  成石浩司
- Organizer
  岩手医科大学歯学部オープンリサーチ・プロジェクト研究成果発表会
- Place of Presentation
  盛岡シンポジウム
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] SPT期における歯周組織の維持・改善に対する塗布用ブラシ一体型歯周病薬の効果2010
- Author(s)
  畑中加珠, 成石浩司, 前田博史, 高柴正悟, 犬伏順也, 安田多賀子, 西田美恵子
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] IL-1raによるマウス骨芽細胞様細胞MC3T3-E1におけるIL-1誘導性OPGおよびIL-6の産生制御2010
- Author(s)
  久保克行, 大森一弘, 成石浩司, 冨山高史, 小林寛也, 山口知子, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯周病原細菌の感染による全身性炎症性反応に抗する免疫応答の意義2010
- Author(s)
  成石浩司, 園井教裕, 大森一弘, 前田博史, 高柴正悟, 國松和司
- Organizer
  第133回日本歯科保存学会秋期学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases2009
- Author(s)
  Koji Naruishi
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Year and Date
  2009-11-29
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases2009
- Author(s)
  Koji Naruishi
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Year and Date
  2009-11-29
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases.2009
- Author(s)
  成石浩司
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases2009
- Author(s)
  Koji Naruishi
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Year and Date
  2009-11-29
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] 歯肉線維芽細胞を標的としたカベオリン-1および可溶性gp130によるIL-6誘導性VEGF産生の抑制制御2009
- Author(s)
  山口知子, 成石浩司, 大森一弘, 新井英雄, 高柴正悟
- Organizer
  第130回日本歯科保存学会春期学術大会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] IL-lαおよびIL-1βによるマウス骨芽細胞様細胞MC3T3-E1の動態におけるMAPK系の関与2008
- Author(s)
  冨山高史, 成石浩司, 大森一弘, 久保克行, 前田博史, 新井英雄, 高柴正悟
- Organizer
  第129回日本歯科保存学会秋季学術大会
- Place of Presentation
  富山市
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] α3β1 integrin-mediated MC3T3-E1 osteoblasts adherence induced by in terleukin-1α2008
- Author(s)
  Takashi Tomiyama, Koji Naruishi, Kazuhiro Omori, Hiroshi Maeda, Shogo Takashiba
- Organizer
  56^<th> Annual Meeting, 2008, Japanese Associationfor Dental Research
- Place of Presentation
  Nagoya
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] ラツト根管治療モデルを用いた根尖周囲組織の遺伝子マイクロアレイ解析に基づいた根尖病巣治癒病態の考察2008
- Author(s)
  冨山高史, 成石浩司, Zulema Arias, 山城圭介, 前田博史, 新井英雄, 高柴正悟
- Organizer
  日本歯科保存学会 2008年春季学術大会(第128回)
- Place of Presentation
  新潟市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20592226

1. TAKASHIBA Shogo (50226768)

# of Collaborated Projects : 8results

# of Collaborated Products : 17results
2. TANIMOTO Ichiro (00280686)

# of Collaborated Projects : 4results

# of Collaborated Products : 1results
3. 木戸淳一 (10195315)

# of Collaborated Projects : 4results

# of Collaborated Products : 1results
4. NAGATA Toshihiko (10127847)

# of Collaborated Projects : 3results

# of Collaborated Products : 5results
5. SHIOMI Nobuyuki (90432632)

# of Collaborated Projects : 3results

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49. 稲垣裕司 (50380019)

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NARUISHI Koji 成石 浩司

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人工細胞を用いたオーラルケアシステムの基礎研究Ongoing

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糖尿病関連歯周炎のIL-6動態に着目したマクロファージ・線維芽細胞クロストークPrincipal InvestigatorOngoing

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最終糖化産物AGEsによる糖尿病関連歯周炎の重症化機序の解明と診断システムの構築Ongoing

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最終糖化産物とインフラマソームの関連から探る糖尿病関連歯周炎の病態Ongoing

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細胞性バイオマーカーを用いたインプラント疾患の診断とデバイス開発Ongoing

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ＡＰ－１によるカテプシン産生制御に着目した歯肉増殖症・歯周病診断の新機軸Principal Investigator

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Possible Mechanisms of Progression of Periodontits by MMP-3 in Diabetic PatientsPrincipal Investigator

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糖尿病患者の歯周病悪化を誘発する新規因子の網羅的な解析および同定Principal Investigator

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NARUISHI Koji 成石浩司