• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Yamasaki Kazuhiko  山崎 和彦

… Alternative Names

YAMASAKI Kazuhiko  山崎 和彦

Less
Researcher Number 00358243
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0320-9697
Affiliation (Current) 2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help 2018 – 2021: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
2016: 国立研究開発法人・産業技術総合研究所, バイオメディカル研究部門, 主任研究員
2015 – 2016: 国立研究開発法人産業技術総合研究所, その他部局等, 研究員
2013 – 2014: 独立行政法人産業技術総合研究所, その他部局等, 研究員
2012 – 2014: 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 … More
2010: National Institute of Advanced Industrial Science and Technology, バイオメディカル研究部門, 主任研究員
2008 – 2009: National Institute of Advanced Industrial Science and Technology, 年齢軸生命工学研究センター, 研究チーム長
2005 – 2006: 独立行政法人産業技術総合研究所, 年齢軸生命工学研究センター, 研究チーム長 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Basic Section 43020:Structural biochemistry-related / Basic Section 43020:Structural biochemistry-related
Except Principal Investigator
Drug development chemistry / Mathematical physics/Fundamental condensed matter physics
Keywords
Principal Investigator
NMR / 表面プラズモン共鳴 / X線結晶解析 / 転写制御 / X線結晶構造解析 / 膜タンパク質 / NMR分光法 / 立体構造情報 / 阻害剤開発 / 寄生原虫症 … More / 特異性変換 / 結合強化 / 立体構造解析 / 化学合成 / 非天然アミノ酸 / 変異導入 / 立体構造 / タンパク質認識 / 糖鎖認識 / レクチン / CUT domain / surface plasmon resonance / X-ray crystallography / immune T-cell / transcription regulation / protein-DNA interaction / タンパク質・核酸相互作用 / CUTドメイン / 免疫T細胞 / 蛋白質・核酸相互作用 / タンパク質核酸相互作用 / がん / 核酸創薬 / 転写因子 / 認識コンセンサス配列 / 等温滴定熱量分析 / NMR分光解析 / 免疫細胞分化 / 協同性と競合性 / DNA結合タンパク質 … More
Except Principal Investigator
DNA / モルヒネ / 新規核酸アプタマー探索法 / 鎮痛効果 / 膜小胞 / 新規核酸リガンド探索法 / G蛋白質受容体 / DNAアプタマー / Cell SELEX法 / 創薬基盤技術 / 鎮痛 / 探索方法 / オピオイド受容体 / GPCRs / アプタマー / 情報科学・計算科学の融合 / 結晶構造のリファインメント解析技術 / GTP加水分解反応メカニズム / 細胞内情報伝達の生体反応 / 自動解析ウェブサービスシステム / 転写制御配列の自動同定システム / ゲノムDNAの高次構造モデル / 生体触媒反応における電子構造のダイナミクス / 核酸 / タンパク質 / 生体高分子 / 生命物理学 / 量子科学 / 情報科学 / 計算科学 / 多様体 / ゲノム情報学 / 情報幾何学 / 機械学習 / 情報理論 / 電子構造理論 / 転写制御 / リボザイム / ゲノムDNA / 情報微分幾何学 / パターン認識 / 電子状態理論 / ハイブリッド触媒 / 電子ダイナミクス Less
  • Research Projects

    (7 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (11 People)
  •  Structural biology of Trypanosoma brucei GPI phospholipase c and the development of selective inhibitors against itPrincipal Investigator

    • Principal Investigator
      山崎 和彦
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of novel probes for a glycan for medicinal technologyPrincipal Investigator

    • Principal Investigator
      Yamasaki Kazuhiko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Creation of novel DNA ligands with potent analgesic action against MOR opioid receptor and elucidation of molecular mechanisms.

    • Principal Investigator
      IKEMOTO Mitsushi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Theoretical investigation of reaction fields of biological macromolecular systems based on quantum sciences and mathematical informatics

    • Principal Investigator
      Tateno Masaru
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Mathematical physics/Fundamental condensed matter physics
    • Research Institution
      University of Hyogo
  •  Development of nucleic acids therapeutics against multiple domains of transcription factor SATB1Principal Investigator

    • Principal Investigator
      YAMASAKI Kazuhiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Sequence-specificity and binding-cooperativity of multiple DNA-binding domains of CUT-homeodomain transcription factorsPrincipal Investigator

    • Principal Investigator
      YAMASAKI Kazuhiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Structural biology of transcriptional regulation by SATB1 that binds to matrix attachment region of DNAPrincipal Investigator

    • Principal Investigator
      YAMASAKI Kazuhiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      National Institute of Advanced Industrial Science and Technology (AIST)

All 2024 2023 2022 2019 2018 2017 2016 2015 2014 2013 2008 2007 2006 Other

All Journal Article Presentation Patent

  • [Journal Article] Structural Basis for Specific Recognition of Core Fucosylation in N-glycans by Pholiota Squarrosa Lectin (PhoSL)2019

    • Author(s)
      Kazuhiko Yamasaki, Tomomi Kubota, Tomoko Yamasaki, Izuru Nagashima, Hiroki Shimizu, Ryu-Ichiro Terada, Hiroshi Nishigami, Jiyoung Kang, Masaru Tateno, Hiroaki Tateno
    • Journal Title

      Glycobiology

      Volume: 29 Issue: 7 Pages: 576-587

    • DOI

      10.1093/glycob/cwz025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02397
  • [Journal Article] Simulated Annealing-Extended Sampling for Multicomponent Decomposition of Spectral Data of DNA Complexed with Peptide2017

    • Author(s)
      Jiyoung Kang, Kazuhiko Yamasaki, Kuniaki Sano, Ken Tsutsui, Kimiko M. Tsutsui, and Masaru Tateno
    • Journal Title

      J. Phys. Soc. Jpn.

      Volume: 86 Issue: 1 Pages: 014802-014802

    • DOI

      10.7566/jpsj.86.014802

    • NAID

      40021057753

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Journal Article] The combination of sequence-specific and nonspecific binding modes of transcription factor SATB12016

    • Author(s)
      Kazuhiko Yamasaki and Tomoko Yamasaki
    • Journal Title

      Biochemical Journal

      Volume: 473 Issue: 19 Pages: 3321-3339

    • DOI

      10.1042/bcj20160236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570119, KAKENHI-PROJECT-25287099, KAKENHI-PROJECT-24570144
  • [Journal Article] Structural basis for recognition of the matrix attachment region of DNA by transcription factor SATB12007

    • Author(s)
      KAZUHIKO YAMASAKI; TOSHIHIKO AKIBA, TOMOKO YAMASAKI, KAZUAKI HARATA
    • Journal Title

      Nucleic Acids Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17570103
  • [Journal Article] Structural basis for recognition of the matrix attachment region of DNA by transcription factor SATB12007

    • Author(s)
      Kazuhiko Yamasaki
    • Journal Title

      Nucleic Acids Research (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17570103
  • [Journal Article] Solution Structure and DNA-binding Mode of the Matrix Attachment Region-binding Domain of the Transcription Factor SATB1 That Regulates the T-cell Maturation2006

    • Author(s)
      H.Yamaguchi, M.Tateno, K.Yamasaki
    • Journal Title

      Journal of Biological Chemistry 281(8)

      Pages: 5319-5327

    • Data Source
      KAKENHI-PROJECT-17570103
  • [Journal Article] Solution structure and DNA-binding mode of the matrix attachment region-binding domain of the transcription factor. SATB1 that regulates the T-cell maturation2006

    • Author(s)
      HIROSHI YAMAGUCHI, MASARU TATENO, KAZUHIKO YAMASAKI
    • Journal Title

      Journal of Biological Chemistry 281(8)

      Pages: 5318-5327

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17570103
  • [Patent] スギタケレクチン及び/又はその変異ペプチドを含むウイルス感染症の治療用又は診断用医薬組成物2024

    • Inventor(s)
      山崎 和彦、舘野 浩章、清水 弘樹、森田 公一、ヌグエ トン, ミャ ミャッ
    • Industrial Property Rights Holder
      国立研究開発法人産業技術総合研究所、国立大学法人長崎大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2024-512384
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-18H02397
  • [Patent] スギタケレクチン及び/又はその変異ペプチドを含むウイルス感染症の治療用又は診断用医薬組成物2023

    • Inventor(s)
      山崎和彦、舘野浩章、清水弘樹、森田公一、NgweTun M.M.
    • Industrial Property Rights Holder
      産業技術総合研究所、長崎大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18H02397
  • [Patent] スギタケレクチン及び/又はその変異ペプチドを含むウイルス感染症の治療用又は診断用医薬組成物2022

    • Inventor(s)
      山崎 和彦, 舘野 浩章, 清水 弘樹, 森田 公一, ミャ ミャッヌグエ トン
    • Industrial Property Rights Holder
      産業技術総合研究所 長崎大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-052125
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18H02397
  • [Presentation] コアフコース結合レクチンPhoSLによる特異的認識機構の構造基盤2018

    • Author(s)
      山崎和彦
    • Organizer
      日本生化学会年会(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-18H02397
  • [Presentation] NMR分光法によるコアフコース認識レクチンPhoSLの三量体溶液構造とフコース認識機構2018

    • Author(s)
      山崎和彦、山崎智子、舘野浩章
    • Organizer
      日本生化学会関東支部例会
    • Data Source
      KAKENHI-PROJECT-18H02397
  • [Presentation] Structural and thermodynamic mechanisms of selectivity and cooperativity in recognition of supercoiled DNA-recognition (SDR) peptide and crossover DNA2017

    • Author(s)
      Hiroshi Nishigami, Jiyoung Kang, Kakeru Sakabe, Kuniaki Sano, Kimiko M. Tsutsui, Ken Tsutsui, Kazuhiko Yamasaki, Masaru Tateno
    • Organizer
      2016 Leading Program Evaluation Conference
    • Place of Presentation
      Center for Advanced Science and Technology Hyogo (CAST)
    • Year and Date
      2017-03-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] Enhancement of sampling space in multivariate analysis of experimental big data in various biological sciences2016

    • Author(s)
      Jiyoung Kang, Kazuhiko Yamasaki, and Masaru Tateno
    • Organizer
      The 54th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Tsukuba International Congress Center
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] Novel extended sampling method for multivariate analysis calculation of experimental big data in biochemistry and bioinformatics2016

    • Author(s)
      Jiyoung Kang, Kazuhiko Yamasaki, and Masaru Tateno
    • Organizer
      The 16th Annual Meeting of the Protein Science Society of Japan
    • Place of Presentation
      Fukuoka International Congress Center
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] Molecular dynamics docking simulation to elucidate selective binding mechanisms of supercoiled-DNA recognition (SDR) peptide and spatially-crossover DNA2016

    • Author(s)
      Hiroshi Nishigami, Kakeru Sakabe, Jiyoung Kang, Kuniaki Sano, Kimiko Tsutsui, Ken Tsutsui, Kazuhiko Yamasaki, and Masaru Tateno
    • Organizer
      The 39th Annual Meeting of The Molecular Biology Society of Japan
    • Place of Presentation
      Pacifico Yokohama
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] Molecular dynamics docking study on selective binding mechanisms of supercoiled-DNA recognition (SDR) peptide and spatially-crossover DNA2016

    • Author(s)
      Hiroshi Nishigami, Kakeru Sakabe, Jiyoung Kang, Kuniaki Sano, Kimiko Tsutsui, Ken Tsutsui, Kazuhiko Yamasaki, and Masaru Tateno
    • Organizer
      The 54th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Tsukuba International Congress Center
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] Structural modeling of negatively-supercoiled DNA recognition peptide complexed with crossover DNA2015

    • Author(s)
      Kakeru Sakabe, Jiyoung Kang, Kazuhiko Yamasaki, Kuniaki Sano, Kimiko M. Tsutsui, Ken Tsutsui, Masaru Tateno
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学大会 2015
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] Structural modeling of supercoiled DNA recognition peptide complexed wth crossover DNA2015

    • Author(s)
      Kakeru Sakabe, Jiyoung Kang, Kazuhiko Yamasaki, Masaru Tateno
    • Organizer
      3rd International Picobiology Institute Symposium
    • Place of Presentation
      先端科学技術センター(兵庫県赤穂郡)
    • Year and Date
      2015-12-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] 等温滴定型カロリメトリーとNMR分光によるタンパク質・核酸相互作用解2014

    • Author(s)
      山崎和彦、山崎智子
    • Organizer
      GE Life Sciences Day 2014
    • Place of Presentation
      パシフィコ横浜会議センター
    • Year and Date
      2014-08-01
    • Data Source
      KAKENHI-PROJECT-24570144
  • [Presentation] 転写因子SATBIのDNA認識における弱い配列特異的結合と強い非特異的結合の組み合わせ2014

    • Author(s)
      山崎 和彦, 山崎 智子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-20570119
  • [Presentation] SBP75の選択的DNA高次構造認識2013

    • Author(s)
      佐野訓明、山崎和彦、筒井公子、筒井 研
    • Organizer
      第86回 日本生化学会大会
    • Place of Presentation
      パシィフィコ横浜 (横浜市西区)
    • Data Source
      KAKENHI-PROJECT-25287099
  • [Presentation] 転写因子SATBIの複数のDNA結合ドメインによるDNA, 認識のNMR解析2008

    • Author(s)
      山崎和彦, 山崎智子
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20570119
  • [Presentation] 転写因子SATB1の複数のDNA結合ドメインによるDNA認識のNMR解析2008

    • Author(s)
      山崎和彦、山崎智子
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20570119
  • [Presentation] 転写因子SATB1のDNA認識における弱い配列特異的結合と強い非特異的結合の組み合わせ

    • Author(s)
      山崎和彦、山崎智子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2014-10-16 – 2014-10-17
    • Data Source
      KAKENHI-PROJECT-24570144
  • 1.  MIYAGISHI Makoto (30323538)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  OKADA Tomoko (30344146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Tateno Masaru (40291926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  KINO HIORI (70282605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  IKEMOTO Mitsushi (50356424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  ISHII Noriyuki (10261174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  筒井 公子 (70144748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  清水 弘樹 (30344716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  舘野 浩章 (30450670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  久保田 智巳 (90356923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  IBRAHIM MOHAMMED AUWAL
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi