Yasuda Shinsuke 保田晋助

… Alternative Names

YASUDA Shinsuke 保田晋助

Less

Researcher Number	00374231
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2019 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2017 – 2018: 北海道大学, 医学研究院, 准教授 2016: 北海道大学, 医学研究科, 准教授 2011 – 2016: 北海道大学, 医学(系)研究科(研究院), 講師 … More 2007 – 2010: Hokkaido University, 大学院・医学研究科, 助教 2006: 北海道大学, 大学院医学研究科, 助手 2005: 北海道大学, 大学院・医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Laboratory medicine
Keywords	Principal Investigator RasGRP4 / 関節リウマチ / 全身性エリテマトーデス / 抗リン脂質抗体症候群 / RasGRP1 / 血管新生 / アンギオスタチン / 自然免疫 / 細胞内シグナル / RasGRP … More / 滑膜線維芽細胞 / TNFα / MAPキナーゼ / farnesyltransferase / Ras / 線維芽細胞様滑膜細胞 / 血栓症 / β2-グリコプロテインI / スプライスバリアント / スプライス異常 / 自己免疫疾患 / β_2グリコプロティンI / β_2グリコプロテインI … More Except Principal Investigator 酸化低密度リポタンパク質　(oxLDL) / PET イメージング / 酸化脂質 / 変異　β2GPI-DV / β2－グリコプロテインI　（β2GPI） / 質量分析 / 標的医療 / 脂質メタボローム / 分子イメージング / PETイメージング / LC-MSMS / 酸化リポタンパク質 / 酸化資質 / 質量顕微鏡 / 変異β2GPI-DV / β2-グリコプロテインI　(β2GPI) / LC-MS/MS / リピドミクス / メタボロミクス / 抗リン脂質抗体症候群 / 血管新生 / 血栓・止血 / Beta2-glycoprotein I / 動脈硬化 Less

自然免疫および血管内皮障害に着目したSLE・APSの新規治療法の開発Principal Investigator
- Principal Investigator
  
  保田晋助
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo Medical and Dental University
Amendment of abnormal RasGRP signaling in patients with systemic autoimmunityPrincipal Investigator
- Principal Investigator
  
  Yasuda Shinsuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo Medical and Dental University
  Hokkaido University
The mechanism how RasGRP4 promotes proliferation of synovial fibroblasts in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Yasuda Shinsuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Hokkaido University
Establishment of Molecular Imaging and Lipidomics Technologies for Early Diagnosis of Atherosclerotic Disease
- Principal Investigator
  
  MATSUURA Eiji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
Role of recombinant nicked beta2-glycoprotein I domain V in angiogenesisPrincipal Investigator
- Principal Investigator
  
  YASUDA Shinsuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Hokkaido University
Abnormal expressions of RasGRPs in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  YASUDA Shinsuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Hokkaido University
アンギオスタチンを介したニックβ_2グリコプロテインIの血管新生に与える影響Principal Investigator
- Principal Investigator
  
  保田晋助
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Hokkaido University

[Book] 顕微鏡的多発血管炎2012
- Author(s)
  保田　晋助
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-23591431
[Book] 全身性エリテマトーデスに対する抗体治療–分子標的治療開発の道のりと現状, 別冊医学のあゆみ,抗体医薬Update–開発コンセプトから最新治療実績まで2012
- Author(s)
  保田晋助,小池隆夫, (中山俊憲・中島裕史編)
- Total Pages
  146
- Publisher
  医歯薬出版株式会社, (東京都)
- Data Source
  KAKENHI-PROJECT-23591431
[Book] 別冊医学のあゆみ, 抗体医薬 Update – 開発コンセプトから最新治療実績まで2012
- Author(s)
  保田晋助, 小池隆夫
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23591431
[Book] 顕微鏡的多発血管炎, 膠原病の肺合併症診療マニュアル2012
- Author(s)
  保田晋助, (宮坂信之編)
- Total Pages
  207
- Publisher
  医薬ジャーナル社, (大阪市)
- Data Source
  KAKENHI-PROJECT-23591431
[Book] 別冊日本臨床呼吸器症候群(第2版)II2009
- Author(s)
  保田晋助・小池隆夫
- Total Pages
  692
- Publisher
  株式会社日本臨床社
- Data Source
  KAKENHI-PROJECT-20591163
[Book] よくわかる関節リウマチのすべて「関節リウマチとはどんな病気か」2009
- Author(s)
  保田晋助, 小池隆夫
- Total Pages
  278
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-20591163
[Book] よくわかる関節リウマチのすべて(「関節リウマチとはどんな病気か」)2009
- Author(s)
  保田晋助, 小池隆夫
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-20591163
[Book] 呼吸器症候群(第2版)(「原発性抗リン脂質抗体症候群」)(別冊日本臨床)2009
- Author(s)
  保田晋助, 小池隆夫
- Publisher
  株式会社日本臨床
- Data Source
  KAKENHI-PROJECT-20591163
[Book] よくわかる関節リウマチのすべて2009
- Author(s)
  保田晋助・小池隆夫
- Total Pages
  278
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-20591163
[Book] よくわかる関節リウマチのすべて2008
- Author(s)
  保田晋助, 小池隆夫
- Publisher
  永井書店(In press)
- Data Source
  KAKENHI-PROJECT-17689031
[Book] 「関節痛」、症候から迫る内科診療・典型例と非典型例によるアプローチ2007
- Author(s)
  深江淳, 保田晋助, 小池隆夫
- Total Pages
  10
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17689031
[Book] β_2-glycoprotein I and Anti-β_2-glycoprotein I antibodies In: Khamashta MA, editor. Hughes Syndrome.2006
- Author(s)
  Yasuda S, Atsumi T, Koike T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17689031
[Book] Hughes Syndrome (Khamashta MA, editor) (Antiphospholipid syndrome 2^<nd> edition)2006
- Author(s)
  Yasuda S, Atsumi T, Koike T
- Total Pages
  598
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] MicroRNA-9 ameliorates destructive arthritis through down-regulation of NF-κB1-RANKL pathway in fibroblast-like synoviocytes2020
- Author(s)
  Lee Wen Shi、Yasuda Shinsuke、Kono Michihiro、Kudo Yuki、Shimamura Sanae、Kono Michihito、Fujieda Yuichiro、Kato Masaru、Oku Kenji、Shimizu Tomohiro、Onodera Tomohiro、Iwasaki Norimasa、Atsumi Tatsuya
- Journal Title
  
  Clinical Immunology
  
  Volume: 212 Pages: 108348-108348
- DOI
  10.1016/j.clim.2020.108348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-18K08380
[Journal Article] MicroRNA-9 ameliorates destructive arthritis through down-regulation of NF-κB1-RANKL pathway in fibroblast-like synoviocytes.2020
- Author(s)
  Lee WS, Yasuda S, Kono M, Kudo Y, Shimamura S, Kono M, Fujieda Y, Kato M, Oku K, Shimizu T, Onodera T, Iwasaki N, Atsumi T
- Journal Title
  
  Clinical Immunology
  
  Volume: 212 Issue: 4 Pages: 108348-108348
- DOI
  10.1007/s00774-020-01089-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08380, KAKENHI-PROJECT-20K11597
[Journal Article] RA滑膜における異所性RasGRP2の発現が破壊性関節炎に寄与する2019
- Author(s)
  保田晋助, 中村浩之, 嶋村抄苗
- Journal Title
  
  リウマチ科
  
  Volume: 62 Pages: 375-380
- Data Source
  KAKENHI-PROJECT-18K08380
[Journal Article] Tocilizumab reduced production of scleroderma-related autoantibodies and anti-cyclic citrullinated protein antibodies in two patients overlapping scleroderma and rheumatoid arthritis2018
- Author(s)
  Kono M, Yasuda S, Kono M, Atsumi T
- Journal Title
  
  Scand J Rheumatol
  
  Volume: 印刷中 Issue: 3 Pages: 248-250
- DOI
  10.1080/03009742.2017.1297482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Decreased expression of Serine/arginine-rich splicing factor 1 in T cells from patients with active systemic lupus erythematosus accounts for reduced expression of RasGRP1 and DNA methyltransferase 12018
- Author(s)
  Kono M, Kurita T, Yasuda S, Kono M, Fujieda Y, Bohgaki T, Katsuyama T, Tsokos GC, Moulton VR, Atsumi T.
- Journal Title
  
  Arthritis Rheumatol
  
  Volume: 70 Issue: 12 Pages: 2046-2056
- DOI
  10.1002/art.40585
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08380
[Journal Article] Ectopic RASGRP2 (CalDAG-GEFI) Expression in Rheumatoid Synovium Contributes to the Development of Destructive Arthritis2018
- Author(s)
  Nakamura H, Shimamura S, Yasuda S, Kono M, Kono M, Fujieda Y, Kato M, Oku K, Bohgaki T, Shimizu T, Iwasaki N, Atsumi T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 77 Issue: 1 Pages: 1765-1772
- DOI
  10.1186/s13075-018-1647-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08380
[Journal Article] Effectiveness of whole-body magnetic resonance imaging for the efficacy of biologic anti-rheumatic drugs in patients with rheumatoid arthritis: a retrospective pilot study2017
- Author(s)
  Kono M, Kamishima T, Yasuda S, Sakamoto K, Abe S, Noguchi A, Watanabe T, Shimizu Y, Oku K, Bohgaki T, Amengual O, Horita T, Atsumi T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 27 Pages: 953-960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Clinical Benefit of 1-Year Certolizumab Pegol (CZP) Add-on Therapy to Methotrexate Treatment in Early Rheumatoid Arthritis Patients was Observed Following CZP Discontinuation: 2-Year Results of the C-OPERA Study2017
- Author(s)
  Atsumi T, Tanaka Y, Yamamoto K, Takeuchi T, Yamanaka H, Ishiguro N, Eguchi K, Watanabe A, Origasa H, Yasuda S, Yamanishi Y, Kita Y, Matsubara T, Iwamoto M, Shoji T, Togo O, Okada T, van der Heijde D, Miyasaka N, Koike T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 76 Issue: 8 Pages: 1348-1356
- DOI
  10.1136/annrheumdis-2016-210246
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Maintenance Treatment using Abatacept with Dose Reduction after Achievement of Low Disease Activity in Patients with Rheumatoid Arthritis (MATADOR) - A prospective, multicenter, single arm pilot clinical trial2017
- Author(s)
  Yasuda S, Ohmura K, Kanazawa H, Kurita K, Kon Y, Ishii T, Fujieda Y, Jodo S, Tanimura K, Minami M, Izumiyama T, Matsumoto T, Amasaki Y, Suzuki Y, Kasahara H, Yamauchi N, Kato M, Kamishima T, Tsutsumi A, Takemori H, Koike T, Atsumi T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 27 Issue: 6 Pages: 930-937
- DOI
  10.1080/14397595.2017.1286714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Role of apolipoprotein B100 and oxidized low-density lipoprotein in the monocyte tissue factor induction mediated by anti-b2 glycoprotein I antibodies.2016
- Author(s)
  Otomo K, Amengual O, Fujieda Y, Nakagawa H, Kato M, Oku K, Horita T, Yasuda S, Matsumoto M, Nakayama KI, Hatakeyama S, Koike T, Atsumi T
- Journal Title
  
  Lupus
  
  Volume: Epub ahead Issue: 12 Pages: 1288-1298
- DOI
  10.1177/0961203316638165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461466, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-26293230, KAKENHI-PROJECT-15K09514
[Journal Article] Ribophorin II is involved in the tissue factor expression mediated by phosphatidylserine-dependent antiprothrombin antibody on monocytes2016
- Author(s)
  Fujieda Y., Amengual O., Matsumoto M., Kuroki K., Takahashi H., Kono M., Kurita Y., Otomo K., Kato M., Oku K., Bohgaki T., Horita T., Yasuda S., Maenaka K., Hatakeyama S., Nakayama K.I. and Atsumi T. et al.
- Journal Title
  
  Rheumatology
  
  Volume: 印刷中 Issue: 6 Pages: 1117-1126
- DOI
  10.1093/rheumatology/kew005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-25461466, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-26293230, KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-15K09545
[Journal Article] AAA-ATPase p97 suppress apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts2016
- Author(s)
  Kato M, Ospelt C, Kolling C, Shimizu T, Kono M, Yasuda S, Michel BA, Gay RE, Gay S, Klein K, Atsumi T
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 64221-64232
- NAID
  120005905626
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Post-steroid neuropsychiatric manifestations are significantly more frequent in SLE compared with other systemic autoimmune diseases and predict better prognosis compared with de novo neuropsychiatric SLE2016
- Author(s)
  Shimizu Y, Yasuda S, Kato Y, Nakagawa S, Kanda M, Hisada R, Ohmura K, Shimamura S, Shida H, Fujieda Y, Kato M, Oku K, Bohgaki T, Horita T, Kusumi I, Atsumi T
- Journal Title
  
  Autoimmunity Reviews
  
  Volume: Epub ahead Issue: 8 Pages: 786-794
- DOI
  10.1016/j.autrev.2016.03.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461466, KAKENHI-PROJECT-15J00292, KAKENHI-PROJECT-26293230, KAKENHI-PROJECT-15K09514
[Journal Article] The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progression2016
- Author(s)
  Atsumi T, Yamamoto K, Takeuchi T, Yamanaka H, Ishiguro N, Tanaka Y, Eguchi K, Watanabe A, Origasa H, Yasuda S, Yamanishi Y, Kita Y, Matsubara T, Iwamoto M, Shoji T, Okada T, van der Heijde D, Miyasaka N, Koike T
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 75 Issue: 1 Pages: 75-83
- DOI
  10.1136/annrheumdis-2015-207511
- NAID
  120005697202
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-26293230
[Journal Article] Autoantibodies against a complement component 1 q subcomponent contribute to complement activation and recurrent thrombosis/pregnancy morbidity in anti-phospholipid syndrome2016
- Author(s)
  Oku K, Amengual O, Hisada R, Ohmura K, Nakagawa I, Watanabe T, Bohgaki T, Horita T, Yasuda S, Atsumi T
- Journal Title
  
  Rheumatology(Oxford)
  
  Volume: Epub ahead Issue: 8 Pages: 1403-1411
- DOI
  10.1093/rheumatology/kew196
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461466, KAKENHI-PROJECT-26293230, KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-16K09885
[Journal Article] Pulmonary infections following immunosuppressive treatment during hospitalization worsen the short-term vital prognosis for patients with connective tissue disease-associated interstitial pneumonia2015
- Author(s)
  Tanaka M, Koike R, Sakai R, Saito K, Hirata S, Nagasawa H, Kameda H, Hara M, Kawaguchi Y, Tohma S, Takasaki Y, Dohi M, Nishioka Y, Yasuda S, Miyazaki Y, Kaneko Y, Nanki T, Watanabe K, Yamazaki H, Miyasaka N, Harigai M
- Journal Title
  
  Modern Rheumatology
  
  Volume: 25 Issue: 4 Pages: 609-614
- DOI
  10.3109/14397595.2014.980384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Surveillance for the use of mycophenolate mofetil for adult patients with lupus nephritis in Japan2015
- Author(s)
  Yasuda S, Atsumi T, Shimamura S, Ono K, Hiromura K, Sada K, Mori M, Takei S, Kawaguchi Y, Tamura N, Takasaki Y
- Journal Title
  
  Modern Rheumatology
  
  Volume: 25 Issue: 6 Pages: 854-857
- DOI
  10.3109/14397595.2015.1031444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Projectile haemorrhage of a brachial artery in a patient with clinically amyopathic dermatomyositis2015
- Author(s)
  Kono M, Yasuda S, Watanabe T, Atsumi T
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 54 Issue: 8 Pages: 1530-1531
- DOI
  10.1093/rheumatology/kev206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] β2-glycoprotein I/ HLA class II complexes are novel autoantigens in antiphospholipid syndrome.2015
- Author(s)
  Tanimura K, Jin H, Suenaga T, Morikami S, Arase N, Kishida K, Hirayasu K, Kohyama M, Ebina Y, Yasuda S, Horita T, Takasugi K, Ohmura K, Yamamoto K, Katayama I, Sasazuki T, Lanier LL, Atsumi T, Yamada H, Arase H.
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 18 Pages: 2835-2844
- DOI
  10.1182/blood-2014-08-593624
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22133001, KAKENHI-PROJECT-23390112, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-24590584, KAKENHI-PUBLICLY-25133705, KAKENHI-PROJECT-25460565, KAKENHI-PROJECT-25670143, KAKENHI-PROJECT-26462489, KAKENHI-PROJECT-26870334, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-15K15418, KAKENHI-PROJECT-15K15419, KAKENHI-PUBLICLY-26117714, KAKENHI-PROJECT-24591436, KAKENHI-PROJECT-25670503
[Journal Article] An independent validation of the global anti-phospholipid syndrome score in Japanese cohort of patients with antoimmune diseases2015
- Author(s)
  Oku K, Amengual O, Bohgaki T, Horita T, Yasuda S, Atsumi T
- Journal Title
  
  Lupus
  
  Volume: 24 Issue: 7 Pages: 774-775
- DOI
  10.1177/0961203314561284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-15K09545, KAKENHI-PROJECT-24591436, KAKENHI-PROJECT-25350221, KAKENHI-PROJECT-25461466, KAKENHI-PROJECT-26293230
[Journal Article] A national surveillance on current use of mycophenolate mofetil for childhood-onset systemic lupus erythematosus in Japan2015
- Author(s)
  Hara R, Miyazawa H, Nishimura K, Momoi T, Nozawa T, Kikuchi M, Sakurai N, Kizawa T, Shimamura S, Yasuda S, Hiromura K, Sada K, Kawaguchi Y, Tamura N, Takei S, Takasaki Y, Atsumi T, Mori M
- Journal Title
  
  Modern Rheumatology
  
  Volume: 25 Pages: 858-864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514
[Journal Article] Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis patients (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry2015
- Author(s)
  Ryoko Sakai, Soo-Kyung Cho, Toshihiro Nanki, Kaori Watanabe, Hayato Yamazaki, Michi Tanaka, et al , for the REAL Study Group
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 17 Issue: 1 Pages: 74-74
- DOI
  10.1186/s13075-015-0583-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860390, KAKENHI-PROJECT-15K09514
[Journal Article] Assessment of risks for pulmonary infection during 12 months after commencing or intensifying immunosuppressive treatment for active connective tissue diseases: A report from a large-scale prospective cohort study2015
- Author(s)
  Yamazaki H, Sakai R, Koike R, Miyazaki Y, Tanaka M, Nanki T, Watanabe K, Yasuda S, Kurita T, Kaneko Y, Tanaka Y, Nishioka Y, Takasaki Y, Nagasaka K, Nagasawa H, Tohma S, Dohi M, Sugihara T, Sugiyama H, Kawaguchi Y, Inase N, Ochi S, Hagiyama H, Kohsaka H, Miyasaka N, Harigai M
- Journal Title
  
  Journal of Rheumatology
  
  Volume: 42 Issue: 4 Pages: 614-622
- DOI
  10.3899/jrheum.140778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-26461474
[Journal Article] A comparison of incidence and risk factors for serious adverse events in rheumatoid arthritis patients with etanercept or adalimumab in Korea and Japan2014
- Author(s)
  Cho SK, Sakai R, Nanki T, Koike R, Watanabe K, Yamazaki H, Nagasawa H, Tanaka Y, Nakajima A, Yasuda S, Ihata A, Ezawa K, Won S, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Miyasaka N, Bae SC, Harigai M
- Journal Title
  
  Modern Rheumatology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] for the RESEARCH investigators; the REAL Study Group. A comparison of incidence and risk factors for serious adverse events in rheumatoid arthritis patients with etanercept or adalimumab in Korea and Japan2014
- Author(s)
  Cho SK, Sakai R, Nanki T, Koike R, Watanabe K, Yamazaki H, Nagasawa H, Tanaka Y, Nakajima A, Yasuda S, Ihata A, Ezawa K, Won S, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Miyasaka N, Bae SC, Harigai M
- Journal Title
  
  Mod Rheumatol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Long-term outcome in Japanese patients with lupus nephritis2014
- Author(s)
  Kono M, Yasuda S, Kato M, Kanetsuka Y, Kurita T, Fujieda Y, Otomo K, Horita T, Oba K, Kondo M, Mukai M, Yanai M, Fukasawa Y, Atsumi T
- Journal Title
  
  Lupus
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] The risk of serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors decreased over time; a report from the registry of Japanese rheumatoid arthritis patients for long-term safety (REAL) database2014
- Author(s)
  Sakai R, Cho SK, Nanki T, Koike R, Watanabe K, Yamazaki H, Nagasawa H, Amano K, Tanaka Y, Sumida T, Ihata A, Yasuda S, Nakajima A, Sugihara T, Tamura N, Fujii T, Dobashi H, Miura Y, Miyasaka N, Harigai M
- Journal Title
  
  Rheumatol Int
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Decreased expression of Runx1 and lowered production of Foxp3+ CD25+ CD4+ regulatory T cells in systemic sclerosis2014
- Author(s)
  Kataoka H, Yasuda S, Fukaya S, Oku K, Horita T, Atsumi T, Koike T
- Journal Title
  
  Modern Rheumatology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Comparative analysis of different enzyme immunoassays for assessment of phosphatidylserine-dependent antiphospholipid antibodies2014
- Author(s)
  Amengual O, Horita T, Binder W, Norman GL, Shums Z, Kato M, Otomo K, Fujieda Y, Oku K, Bohgaki T, Yasuda S, Atsumi T
- Journal Title
  
  Rheumatol Int
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility2014
- Author(s)
  Jin H, Arase N, Hirayasu K, Kohyama M, Suenaga T, Saito F, Tanimura K, Matsuoka S, Ebina K, Shi K, Toyama-Sorimachi N, Yasuda S, Horita T, Hiwa R, Takasugi K, Ohmura K, Yoshikawa H, Saito T, Atsumi T, Sasazuki T, Katayama I, Lanier LL, Arase H
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111(10) Pages: 3787-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Decreased expression of Runx1 and lowered production of Foxp3+ CD25+ CD4+ regulatory T cells in systemic sclerosis2014
- Author(s)
  Kataoka H, Yasuda S, Fukaya S, Oku K, Horita T, Atsumi T, Koike T
- Journal Title
  
  Mod Rheumatol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] The effect of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis2014
- Author(s)
  Kurita T, Yasuda S, Oba K, Odani T, Kono M, Otomo K, Fujieda Y, Oku K, Bohgaki T, Amenguak O, Horita T, Atsumi T
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Comparative analysis of different enzyme immunoassays for assessment of phosphatidylserine-dependent antiphospholipid antibodies2014
- Author(s)
  Amengual O, Horita T, Binder W, Norman GL, Shums Z, Kato M, Otomo K, Fujieda Y, Oku K, Bohgaki T, Yasuda S, Atsumi T
- Journal Title
  
  Rheumatology International
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility2014
- Author(s)
  Jin H, Arase N, Hirayasu K, Kohyama M, Suenaga T, Saito F, Tanimura K, Matsuoka S, Ebina K, Shi K, Toyama-Sorimachi N, Yasuda S, Horita T, Hiwa R, Takasugi K, Ohmura K, Yoshikawa H, Saito T, Atsumi T, Sasazuki T, Katayama I, Lanier LL, Arase H
- Journal Title
  
  Proceedings of National Academy of Science USA
  
  Volume: 111 Issue: 10 Pages: 3787-3792
- DOI
  10.1073/pnas.1401105111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591431, KAKENHI-PROJECT-23790385, KAKENHI-PROJECT-23790504, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590584, KAKENHI-PROJECT-24591436, KAKENHI-PROJECT-24659223, KAKENHI-PROJECT-24791542, KAKENHI-PUBLICLY-25133705, KAKENHI-PROJECT-25460565, KAKENHI-PROJECT-25670143, KAKENHI-PROJECT-25670455, KAKENHI-PROJECT-25670503, KAKENHI-PROJECT-26861189
[Journal Article] Essential role of p38 mitogen-activated protein kinase pathway in tissue factor gene expression mediated by the phosphatidylserina-dependent antiprothrombin antibody2013
- Author(s)
  Oku K, Amengual O, Zigon P, Horita T, Yasuda S, Atsumi T
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 52(10) Pages: 1775-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Disseminated intravascular coagulation in the presence of antiphospholipid antibodies : differential diagnosis from catastrophic or microangiopathic antiphospholipid syndrome2013
- Author(s)
  Yasuda S
- Journal Title
  
  Intern Med
  
  Volume: 52(2) Pages: 169-70
- NAID
  130003365862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Disseminated intravascular coagulation in the presence of antiphospholipid antibodies: differential diagnosis from catastrophic or microangiopathic antiphospholipid syndrome.2013
- Author(s)
  Yasuda S
- Journal Title
  
  Intern Med
  
  Volume: In press
- NAID
  130003365862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Essential role of the p38 mitogen-activated protein kinase pathway in tissue factor gene expression mediated by the phosphatidylserine-dependent antiprothrombin antibody2013
- Author(s)
  Oku K, Amengual O, Zigon P, Horita T, Yasuda S, Atsumi T
- Journal Title
  
  rheumatology (Oxford)
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] The involvement of CD36 in monocyte activation by antiphospholipid antibodies2013
- Author(s)
  Kato M, Atsumi T, Oku K, Amengual O, Nakagawa H, Fujieda Y, Otomo K, Horita T, Yasuda S, Koike T
- Journal Title
  
  Lupus
  
  Volume: 22(8) Pages: 761-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Phospholipid scramblase 1 expression is enhanced in patients with antiphospholipid syndrome2013
- Author(s)
  Amengual O, Atsumi T, Oku K, Suzuki E, Horita T, Yasuda S, Koike T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23(1) Pages: 81-8
- NAID
  10031167669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] The efficacy of antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events2012
- Author(s)
  Otomo K, Atsumi T, Amengual O, Fujieda Y, Kato M, Oku K, Horita T, Yasuda S, Koike T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64(2) Pages: 504-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Up-regulated expression of HLA-DRB5 transcripts and high frequency of the HLA-DRB5*01:05 allele in scleroderma patients with interstitial lung disease.2012
- Author(s)
  Odani T, Yasuda S, Ota Y, Fujieda Y, Kon Y, Horita T, Kawaguchi Y, Atsumi T, Yamanaka H, Koike T.
- Journal Title
  
  rheumatology (Oxford)
  
  Volume: 51 Pages: 1765-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Predominant prevalence of arterial thrombosis in Japanese patients with the antiphospholipid syndrome2012
- Author(s)
  Fujieda Y, Atsumi T, Amengual O, Odani T, Otomo K, Kato M, Oku K, Kon Y, Horita T, Yasuda S, Koike T
- Journal Title
  
  Lupus
  
  Volume: 21(14) Pages: 1506-14
- NAID
  120005356853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Up-regulated expression of HLA-DRB5 transcripts and high frequency of the HLA-DRB5*01:05 allele in scleroderma patients with interstitial lung disease2012
- Author(s)
  Odani T, Yasuda S, Ota Y, Fujieda Y, Kon Y, Horita T, Kawaguchi Y, Atsumi T, Yamanaka H, Koike T
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 51(10) Pages: 1765-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Predominant prevalence of arterial thrombosis in Japanese patients with antiphospholipid2012
- Author(s)
  Fujieda Y, Atsumi T, Amengual O, Odani T, Otomo K, Kato M, Oku K, Kon Y, Horita T, Yasuda S, Koike T
- Journal Title
  
  syndromeLupus
  
  Volume: 21(14) Issue: 14 Pages: 1506-14
- DOI
  10.1177/0961203312458469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390198, KAKENHI-PROJECT-22591074, KAKENHI-PROJECT-23591431, KAKENHI-PROJECT-24591436
[Journal Article] The efficacy of antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events2012
- Author(s)
  Otomo K, Atsumi T, Amengual O, Fujieda Y, Kato M, Oku K, Horita T, Yasuda S, Koike T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Issue: 2 Pages: 504-512
- DOI
  10.1002/art.33340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591258, KAKENHI-PROJECT-22390198, KAKENHI-PROJECT-22591074, KAKENHI-PROJECT-23591431, KAKENHI-PROJECT-24591436
[Journal Article] Phospholipid scramblase 1 expression is enhanced in patients with antiphospholipid syndrome2012
- Author(s)
  Amengual O, Atsumi T, Oku K, Suzuki E, Horita T, Yasuda S, Koike T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23(1) Issue: 1 Pages: 81-8
- DOI
  10.1007/s10165-012-0642-9
- NAID
  10031167669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390198, KAKENHI-PROJECT-22591074, KAKENHI-PROJECT-23591431, KAKENHI-PROJECT-24591436, KAKENHI-PROJECT-25670455
[Journal Article] The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis.2011
- Author(s)
  Sakai R, Komano Y, Tanaka M, Nanki T, Koike R, Nakajima A, Atsumi T, Yasuda S, Tanaka Y, Saito K, Tohma S, Fujii T, Ihata A, Tamura N, Kawakami A, Sugihara T, Ito S, Miyasaka N, Harigai M.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 21 Issue: 4 Pages: 444-448
- DOI
  10.1007/s10165-011-0421-z
- NAID
  10029513170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis.2011
- Author(s)
  Hashimoto T, Yasuda S, Koide H, Kataoka H, Horita T, Atsumi T, Koike T.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 13 Issue: 5
- DOI
  10.1186/ar3470
- NAID
  120003945421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Hepatitis B virus reactivation by immunosuppressive therapy in patients with autoimmune diseases : Risk analysis in hepatitis B surface antigen-negative cases2011
- Author(s)
  Kato M, Atsumi T, Kurita T, Odani T, Fujieda Y, Otomo K, Horita T, Yasuda S, Koike T
- Journal Title
  
  J Rheumatol
  
  Volume: 38(10) Pages: 2209-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Clinical features of reversible posterior leukoencephalopathy syndrome in patients with systemic lupus erythematosus.2011
- Author(s)
  Fujieda Y, Kataoka H, Odani T, Otomo K, Kato M, Fukaya S, Oku K, Horita T, Yasuda S, Atsumi T, Koike T.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 21 Issue: 3 Pages: 276-281
- DOI
  10.1007/s10165-010-0386-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis2011
- Author(s)
  Hashimoto T, Yasuda S, Koide H, Kataoka H, Horita T, Atsumi T, Koike T
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 13(5)
- NAID
  120003945421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Hepatitis B virus reactivation by immunosuppressive therapy in patients with autoimmune diseases: Risk analysis in hepatitis B surface antigen-negative cases.2011
- Author(s)
  Kato M, Atsumi T, Kurita T, Odani T, Fujieda Y, Otomo K, Horita T, Yasuda S, Koike T.
- Journal Title
  
  J Rheumatol
  
  Volume: 38 Issue: 10 Pages: 2209-2214
- DOI
  10.3899/jrheum.110289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] The short-term role of corticosteroid therapy for pulmonary arterial hypertension associated with connective tissue diseases : report of five cases and a literatural review2011
- Author(s)
  Kato M, Kataoka H, Odani T, Fujieda Y, Otomo K, Oku K, Horita T, Yasuda s, Atsumi T, Tsujino I, Nishimura M, Koike T
- Journal Title
  
  Lupus
  
  Volume: 20 Issue: 10 Pages: 1047-1056
- DOI
  10.1177/0961203311403347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591258, KAKENHI-PROJECT-23591431
[Journal Article] The short-term role of corticosteroid therapy for pulmonary arterial hypertension associated with connective tissue diseases : report of five cases and a literatural review2011
- Author(s)
  Kato M, Kataoka H, Odani T, Fujieda Y, Otomo K, Oku K, Horita T, Yasuda S, Atsumi T, Tsujino I, Nishimura M, Koike T
- Journal Title
  
  Lupus
  
  Volume: 20(10) Pages: 1047-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] Plasma gelsolin facilitates interaction between beta(2) glycoprotein I and alpha5beta1 integrin.2011
- Author(s)
  Bohgaki M, Matsumoto M, Atsumi T, Kondo T, Yasuda S, Horita T, Nakayama KI, Okumura F, Hatakeyama S, Koike T
- Journal Title
  
  J Cell Mol Med. 15(1)
  
  Pages: 141-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis2011
- Author(s)
  Sakai R, Komano Y, Tanaka M, Nanki T, Koike R, Nakajima A, Atsumi T, Yasuda S, Tanaka Y, Saito K, Tohma S, Fujii T, Ihata A, Tamura N, Kawakami A, Sugihara T, Ito S, Miyasaka N, Harigai M
- Journal Title
  
  Mod Rheumatol
  
  Volume: 21(4) Pages: 444-8
- NAID
  10029513170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591431
[Journal Article] 強皮症の画像診断2010
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科 44(2)
  
  Pages: 146-150
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] セルトリズマブ2010
- Author(s)
  保田晋助
- Journal Title
  
  Pharma Medica. 28(3)
  
  Pages: 53-55
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Nicked β2-glycoprotein IとAngiostatin Kringle 1-4.5の血管新生に与える影響2010
- Author(s)
  中川久子, 保田晋助, 松浦栄次, ほか
- Journal Title
  
  血栓止血誌
  
  Volume: 21 Pages: 314-318
- NAID
  10026400495
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] 全身性エリテマトーデスの生命予後は改善したか2010
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科 44(4)
  
  Pages: 354-357
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] 強皮症の画像診断2010
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科
  
  Volume: 44 Pages: 146-150
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Increased expression of phospholipid scramblase 1 in monocytes from patients with systemic lupus erythematosus.2010
- Author(s)
  Suzuki E, Amengual O, Atsumi T, Oku K, Hashimoto T, Kataoka H, Horita T, Yasuda S, Ieko M, Fukushima K, Koike T
- Journal Title
  
  J Rheumatol. 37(8)
  
  Pages: 1639-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] 全身性エリテマトーデスの生命予後は改善したか2010
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科
  
  Volume: 44 Pages: 354-357
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Pathophysiology of beta2-glycoprotein I in antiphospholipid syndrome.2010
- Author(s)
  Matsuura E, Shen L, Matsunami Y, Quan N, Makarova M, Geske FJ, Boisen M, Yasuda S, Kobayashi K, Lopez LR
- Journal Title
  
  Lupus. 19(4)
  
  Pages: 379-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] セルトリズマブ2010
- Author(s)
  保田晋助
- Journal Title
  
  Pharma Medica
  
  Volume: 28 Pages: 53-55
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Nicked β_2-glycoprotein I binds angiostatin 4.5(plasminogen kringle 1-5)and attenuates its antiangiogenic property.2009
- Author(s)
  Nakagawa H, Yasuda S, Matsuura E, et al
- Journal Title
  
  Blood 114
  
  Pages: 2553-2559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Nicked β_2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property.2009
- Author(s)
  Nakagawa H, Yasuda S, Matsuura E, Kobayashi K, Ieko M, Kataoka H, Horita T, Atsumi T, Koike T
- Journal Title
  
  Blood 114(12)
  
  Pages: 2553-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] 関節リウマチとビタミンD.2009
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科 42(5)
  
  Pages: 540-544
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] The effects of phosphatidylserine-dependent antiprothrombin antibody on thrombin generation.2009
- Author(s)
  Sakai Y, Atsumi T, Ieko M, Amengual O, Furukawa S, Furusaki A, Bohgaki M, Kataoka H, Horita T, Yasuda S, Koike T
- Journal Title
  
  Arthritis Rheum. 60(8)
  
  Pages: 2457-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] 自己免疫の発症とRasGRP1.2009
- Author(s)
  保田晋助
- Journal Title
  
  臨床免疫・アレルギー科 51(4)
  
  Pages: 356-362
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Antiphospholipid antibodies increase the risk of pregnancy-induced hyp ertension and adverse pregnancy outcomes2009
- Author(s)
  Yamada H, Atsumi T, Kobashi G, Ota C, Kato EH, Tsuruga N, Ohta K, Yasuda S, Koike T, Minakami H
- Journal Title
  
  J Reprod Immunol. 79
  
  Pages: 188-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Antiphospholipid antibodies increase the risk of pregnancy-induced hypertension and adverse pregnancy outcomes.2009
- Author(s)
  Yamada H, Atsumi T, Kobashi G, Ota C, Kato EH, Tsuruga N, Ohta K, Yasuda S, Koike T, Minakami H
- Journal Title
  
  J Reprod Immunol. 79
  
  Pages: 188-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] 原発性抗リン脂質抗体症候群2009
- Author(s)
  保田晋助, 小池隆夫
- Journal Title
  
  呼吸器症候群-その他の呼吸器疾患を含めて-(別冊日本臨床新領域別症候群シリーズ) No.9
  
  Pages: 256-260
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Immunological reconstitution after autologous hematopoietic stem cell transplantation in patients with systemic sclerosis : relationship between clinical benefits and intensity of immunosuppression.2009
- Author(s)
  Bohgaki T, Atsumi T, Bohgaki M, Furusaki A, Kondo M, Sato-Matsumura KC, Abe R, Kataoka H, Horita T, Yasuda S, Amasaki Y, Nishio M, Sawada K, Shimizu H, Koike T
- Journal Title
  
  J Rheumatol. 36(6)
  
  Pages: 1240-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Complement activation in patients with primary antiphospholipid syndrome.2009
- Author(s)
  Oku, K, Atsumi, T, Bohgaki, M, Amengual, O, Kataoka, H, Horita, T, Yasuda S, Koike T
- Journal Title
  
  Ann Rheum Dis. 68(6)
  
  Pages: 1030-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] STAT4 single nucleotide polymorphism, rs7574865 G/T, as a risk for antiphospholipid syndrome.2009
- Author(s)
  Horita T, Atsumi T, Yoshida N, Nakagawa H, Kataoka H, Yasuda S, Koike T
- Journal Title
  
  Ann Rheum Dis. 68(8)
  
  Pages: 1366-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Rasguanyl nucleotide-releasing protein 1とリウマチ性疾患2008
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科 40
  
  Pages: 293-297
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases : analysis of 30 cases.2008
- Author(s)
  Fukaya S, Yasuda S, Hashimoto T, Oku K, Kataoka H, Horita T, Atsumi T, Koike T
- Journal Title
  
  Rheumatology. 47(11)
  
  Pages: 1686-1691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Thrombotic microangiopathy in patients with phosphatidylserine dependent antiprothrombin antibodies and antiphospholipid syndrome2008
- Author(s)
  Kon Y, Atsumi T, Hagiwara H, Furusaki A, Kataoka H, Horita T, Yasuda S, Amengual O, Takao K
- Journal Title
  
  Clin Exp Rheumatol 26
  
  Pages: 129-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Thrombotic microangiopathy in patients with phosphatidylserine dependent antiprothrombin antibodies and antiphospholipid syndrome.2008
- Author(s)
  Kon Y, Atsumi T, Hagiwara H, Furusaki A, Kataoka H, Horita T, Yasuda S, Amengual O, Koike T.
- Journal Title
  
  Clinical & Experimental Rheumatology 26
  
  Pages: 129-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Ras guanyl nucleotide-releasing protein 1とリウマチ性疾患2008
- Author(s)
  保田晋助
- Journal Title
  
  リウマチ科 40(3)
  
  Pages: 293-297
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases : analysis of 30 cases2008
- Author(s)
  Fukaya S, Yasuda S, Hashimoto T, Oku K, Kataoka H, Horita T, Atsumi T, Koike T
- Journal Title
  
  Rheumatology 47
  
  Pages: 1686-1691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Thrombotic microangiopathy in patients with phosphatidylserine dependent antiprothrombin antibodies and antiphospholipid syndrome.2008
- Author(s)
  Kon Y, Atsumi T , Hagiwara H, Furusaki A, Kataoka H, Horita T, Yasuda S, Amengual O, Koike T
- Journal Title
  
  Clin Exp Rheumatol. 26(1)
  
  Pages: 129-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] A Polymorphism in the Human Platelet Antigen 6b represents a risk factor for thrombocytopenia in patients with systemic lupus erythematosus.2007
- Author(s)
  Amengual O, Atsumi T, Komano Y, Kataoka H, Horita T, Yasuda S, Koike T
- Journal Title
  
  Arthritis and rheumatism (In press)
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] ニックβ_2-グリコプロテインの構造と機能2007
- Author(s)
  保田晋助
- Journal Title
  
  分子リウマチ 4(1)
  
  Pages: 68-71
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Polymorphism in the Human Platelet Antigen 6b represents a risk factor for thrombocytopenia in patients with systemic lupus erythematosus.2007
- Author(s)
  Amengual O, Atsumi T, Komano Y, Kataoka H, Horita T, Yasuda S, Koike T.
- Journal Title
  
  Arthritis and Rheumatism 56
  
  Pages: 2803-2805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] シェーグレン症候群のB細胞における転写因子E2A・Id3の発現異常2007
- Author(s)
  中川靖子, 片岡浩, 保田晋助, 深江淳, 堀田哲也, 渥美達也, 柏崎晴彦, 小池隆夫, 井上農夫男
- Journal Title
  
  北海道歯学雑誌 28
  
  Pages: 27-35
- NAID
  10019548529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Human monoclonal antibodies against the complex of phosphatidylserine and prothrombin from patients with antiphospholipid antibodies.2007
- Author(s)
  Horita T, Ichikawa K, Kataoka H, Yasuda S, Atsumi T, Koike T.
- Journal Title
  
  Lupus 16
  
  Pages: 509-516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] ニックβ_2-グリコプロテインの構造と機能2007
- Author(s)
  保田晋助
- Journal Title
  
  分子リウマチ 4
  
  Pages: 68-71
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Polymyalgia rheumatica as the manifestation of unclassified aortitis.2007
- Author(s)
  Kataoka H, Atsumi T, Hashimoto T, Horita T, Yasuda S, Koike T
- Journal Title
  
  Modern Rheumatology 18
  
  Pages: 105-108
- NAID
  10024149993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Human monoclonal antibodies against the complex of phosphatidylserine and prothrombin from patients with antiphospholipid antibodies.2007
- Author(s)
  Horita T, Ichikawa K, Kataoka H, Yasuda S, Atsumi T, Koike T
- Journal Title
  
  Lupus (In press)
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Defective expression of ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus.2007
- Author(s)
  Yasuda S, Stevens RL, Terada T, Takeda M, Hashimoto T, Fukae J, Horita T, Kataoka H, Atsumi T, and Koike T.
- Journal Title
  
  Journal of Immunology 179
  
  Pages: 4890-4900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis; a pilot study・2006
- Author(s)
  Furukawa S, Yasuda S, Amengual O, Horita T, Atsumi T, Koike T
- Journal Title
  
  Annals of Rheumatic Diseases (In press)
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] 抗リン脂質抗体の病原性解明へ2006
- Author(s)
  保田晋助, 小池隆夫
- Journal Title
  
  日本臨床免疫学会雑誌 29(5)
  
  Pages: 311-318
- NAID
  10019269275
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis : a pilot study.2006
- Author(s)
  Furukawa S, Yasuda S, Amengual O, Horita T, Atsumi T, Koike T
- Journal Title
  
  Annals of Rheumatic Diseases 65(8)
  
  Pages: 1118-1120
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] 抗リン脂質抗体症候群における最近の進歩2006
- Author(s)
  保田晋助, 小池隆夫
- Journal Title
  
  分子リウマチ 3(1)
  
  Pages: 46-54
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Butyrate suppresses tumor necrosis factor alpha production by regulating specific messenger RNA degradation mediated through a cis-acting AU-rich element.2005
- Author(s)
  Fukae J, Amasaki Y, Yamashita Y, Bohgaki T, Yasuda S, Jodo S, Atsumi T, Koike T
- Journal Title
  
  Arthritis and Rheumatism 52・9
  
  Pages: 2697-2707
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Antigenic structures recognized by anti-β_2-glycoprotein I auto-antibodies.2005
- Author(s)
  Kasahara H, Matsuura E, Kaihara K, Yamamoto D, Kobayashi K, Inagaki J, Ichikawa K, Tsutsumi A, Yasuda S, Atsumi T, Yasuda T, Koike T
- Journal Title
  
  International Immunology 17・12
  
  Pages: 1533-1542
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Pathogenesis of antiphospholipid antibodies: impairment of fibrinolysis and monocyte activation via the p38 mitogen-activated protein kinase pathway.2005
- Author(s)
  Yasuda S, Bohgaki M, Atsumi T, Koike T
- Journal Title
  
  Immunobiology 210・10
  
  Pages: 775-780
- NAID
  120000959527
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase ε/PRSS22.2005
- Author(s)
  Yasuda S, Morokawa N, Wong GW, Rossi A, Madhusudhan MS, Sali A, Askew YS, Adachi R, Silverman GA, Krilis SA, Stevens RL.
- Journal Title
  
  Blood 105(10)
  
  Pages: 3893-3901
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] Research around β_2-glycoprotein I: A major target for antiphospholipid antibodies.2005
- Author(s)
  Atsumi T, Amengual O, Yasuda S, Masuura E, Koike T
- Journal Title
  
  Autoimmunity 38・5
  
  Pages: 377-381
- Data Source
  KAKENHI-PROJECT-17689031
[Journal Article] STAT4 single nucleotide polymorphism, rs7574865 G/T, as a risk for antiphospholipid syndrome
- Author(s)
  Horita T, Atsumi T, Yoshida N, Nakagawa H, Kataoka H, Yasuda S, Koike T
- Journal Title
  
  Ann Rheum Dis (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Journal Article] Complement activation in patients with primary antiphospholipid syndrome
- Author(s)
  Oku,K Atsumi, T Bohgaki, M Amengual, O Kataoka,H Horita, T Yasuda.S, Koike, T
- Journal Title
  
  Ann Rheum DisAnn Rheum Dis (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591163
[Patent] 医薬用組成物2018
- Inventor(s)
  保田晋助、中村浩之
- Industrial Property Rights Holder
  国立大学法人北海道大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-138910
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K08380
[Patent] 医薬用組成物2018
- Inventor(s)
  保田晋助
- Industrial Property Rights Holder
  国立大学法人北海道大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-18K08380
[Presentation] Farnesyltransferase inhibitor suppresses the RasGRP4 and Ras interaction of fibroblast-like synoviocytes from patients with rheumatoid arthritis2018
- Author(s)
  Shimamura S, Yasuda S, Kono Michihito, Fujieda Y, Kato M, Oku K, Bohgaki T, and Atsumi T
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K08380
[Presentation] Decreased expression of Serine/arginine-rich splicing factor 1 in T cells from patients with active systemic lupus erythematosus contributes to reduced expression of RasGRP12018
- Author(s)
  Kono M, Kurita T, Yasuda S, Fujieda Y, Bohgaki T, Katsuyama T, Kono Michihito, Tsokos GC, Moulton VR, Atsumi T
- Organizer
  11th International Congress on Autoimmunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08380
[Presentation] RASGRP1 polymorphism can contribute to clinical manifestations in patients with systemic lupus erythematosus2018
- Author(s)
  14Kono M, Yasuda S, Kono Michihito, Fujieda Y, Kato M, Oku K, Bohgaki T, Atsumi T
- Organizer
  20th Asia Pacific League of Associations for Rheumatology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08380
[Presentation] Decreased expression of Serine/arginine-rich splicing factor 1 in T cells from patients with active systemic lupus erythematosus contributes to reduced expression of RasGRP12018
- Author(s)
  Kono M, Kurita T, Yasuda S, Fujieda Y, Bohgaki T, Katsuyama T, Kono Michihito, Tsokos GC, Moulton VR, Atsumi T
- Organizer
  第62回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08380
[Presentation] 関節リウマチ患者に高発現したRasGRP2は線維芽細胞様滑膜細胞の接着および遊走に関与する2018
- Author(s)
  中村浩之、保田晋助、河野通大、嶋村抄苗、藤枝雄一郎、加藤将、奥健志、坊垣暁之、オルガアメングアル、渥美達也
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K08380
[Presentation] Inhibition of Ras translocation suppresses RasGRP4-induced proliferation of fibroblast-like synoviocytes from patients with rheumatoid arthritis2017
- Author(s)
  Shimamura S, Yasuda S, Kono M, Shimizu Y, Fujieda Y, Kato M, Oku K, Bohgaki T, Atsumi T
- Organizer
  EAGOR meeting, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-15K09514
[Presentation] 強皮症に対する造血幹細胞移植2014
- Author(s)
  保田晋助
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都）
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Role ofβ_2-glycoprotein I Domain V in Angiogenesis2013
- Author(s)
  Yasuda S, Kubota A, Nakagawa H, Kuroki K, Fujieda Y, Bohgaki T, Amengual O, Horita T, Maenaka K, Atsumi T
- Organizer
  CORA meeting
- Place of Presentation
  Novotel Budapest City, Budapest, Hungary
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Diagnosis and treatment of RA in Japan, Experience and recommendations of using Tocilizumab in general2013
- Author(s)
  Yasuda S
- Organizer
  The 6th Rheumatology Meeting in Aubrac
- Place of Presentation
  Best Western Lagiore, Aubrac, France
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] 関節リウマチにおけるRasGRP4の発現異常2013
- Author(s)
  保田晋助
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都国際会議場（京都市）
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Role of b2-glycoprotein I and b2-glycoprotein I domain V in angiogenesis2013
- Author(s)
  Yasuda S, Kubota A, Nakagawa H, Kuroki K, Fujieda Y, Oku K, Bohgaki T, Amengual O, Horita T, Maenaka K, Atsumi T
- Organizer
  Controversies in Rheumatology and Autoimmunity
- Place of Presentation
  ノボテルブダペストシティ（ハンガリー）
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Diagnosis and treatment of RA in Japan2013
- Author(s)
  Yasuda S
- Organizer
  The 6th Rheumatology Meeting in Aubrac
- Place of Presentation
  ベストウエスタンラギオール、オーブラック（フランス）
- Invited
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Role of β2-glycoprotein I Domain V in Angiogenesis2013
- Author(s)
  Yasuda S, Kubota A, Nakagawa H, Kuroki K, Fujieda Y, Bohgaki T, Amengual O, Horita T, Maenaka K, Atsumi T
- Organizer
  CORA meeting
- Place of Presentation
  ノボテルブダペストシティ、ブダペスト（ハンガリー）
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Haematopoietic stem cell transplantation for interstitial lung diseases in patients with systemic sclerosis; Therapeutic effect and evaluation of up-regulated genes2012
- Author(s)
  Yasuda S, Odani T, Ota Y, Fujieda Y, Kon Y, Horita T, Kawaguchi Y, Atsumi T, Yamanaka H, Koike T
- Organizer
  The 8^<th> international congress on autoimmunity
- Place of Presentation
  Palacio de Exposiciones y Congresos de Granada, Granada, Spain
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] IL-6 rationale in RA–from bench side2012
- Author(s)
  Yasuda S
- Organizer
  AURORA meeting
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Aberrant expression of Mx1 in T cells from patients with systemic lupus erythematosus.2011
- Author(s)
  Yasuda S, Kono M, Horita T, Atsumi T, Koike T.
- Organizer
  5th Asian congress on autoimmunity
- Place of Presentation
  Congress Venue (Singapore)
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] HLA-DRB5* 01:05 as a risk for systemic sclerosis and scleroderma-related interstitial lung disease2011
- Author(s)
  Yasuda S, Odani T, Otomo K, Kato M, Horita T, Atsumi T, Koike T
- Organizer
  2011日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ (千葉)
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Aberrant expression of Mx1 in T cells from patients with systemic lupus erythematosus2011
- Author(s)
  Yasuda S, Kono M, Horita T, Atsumi T, Koike T
- Organizer
  5^<th> Asian congress on autoimmunity
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-23591431
[Presentation] Aberrant Splicing of the Transcript of RasGRP4 in the Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis2010
- Author(s)
  T Hashimoto, S Yasuda, H Kataoka, et al.
- Organizer
  The 7th International Congress on Autoimmunity
- Place of Presentation
  GR Ljubljana Exhibition and Convention Centre, Ljubljana, Slovenia
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Standardization of laboratory diagnosis of APS in Asia.2010
- Author(s)
  Yasuda S.
- Organizer
  6^<th> Congress of the Asia Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Nusa Dua Bali
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] ACA, Antiβ2GP1, LA are the only Antiphospolipid Antibodies Test in Diagnose of APS, Contra2010
- Author(s)
  S Yasuda
- Organizer
  6^<th> Congress of the Asia Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Grand Hyatt Hotel, Nusa Dua, Bali, Indonesia 招待講演
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Abnormal splicing of RasGRPs2010
- Author(s)
  S Yasuda
- Organizer
  Monthly Lupus Lecture
- Place of Presentation
  Beth Israel Hospital, Boston, USA 招待講演
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] ACA, Antiβ2GP1, LA are the only Antiphospolipid Antibodies Test in Diagnose of APS, Contra.2010
- Author(s)
  Yasuda S.
- Organizer
  6^<th> Congress of the Asia Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Nusa Dua Bali
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Abnormal splicing of RasGRPs.2010
- Author(s)
  Yasuda S.
- Organizer
  Monthly Lupus Lecture Series
- Place of Presentation
  Beth Israel Deaconess Medical Center, Boston MA
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Standardization of laboratory diagnosis of APS in Asia2010
- Author(s)
  S Yasuda
- Organizer
  6^<th> Congress of the Asia Pacific Society on Throm bosis and Haemostasis
- Place of Presentation
  Grand Hyatt Hotel, Nusa Dua, Bali, Indonesia 招待講演
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] High expressions of RGS1 and Mx1 transcripts in T cells from lupus patients at the active and quiescent state.2009
- Author(s)
  S.Yasuda, Y.Fujieda, T.Hashimoto, et al
- Organizer
  Annual European Congress of Rheumatology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2009-06-10
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Autologous peripheral blood stem cell transplantation as a treatment for the interstitial lung diseases in patients with systemic sclerosis.2009
- Author(s)
  Yasuda S, Odani T, Fujieda Y, Yoshida N, Kataoka H, Horita H, Atsumi T, Koike T.
- Organizer
  4^<th> Asian congress on autoimmunity.
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] High expressions of RGS1 and Mx1 transcripts in T cells from lupus patients at the active and quiescent state.2009
- Author(s)
  Yasuda S, Fujieda Y, Hashimoto T, Miidera H, Kataoka H, Horita T, Atsumi T, Koike T.
- Organizer
  Annual European Congress of Rheumatology 2009
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Alternative Splicing of RasGRP1 in SLE : Frequency, Clinical Features and Cytokine Production2008
- Author(s)
  Yasuda S, et.al.
- Organizer
  アメリカリウマチ学会総会
- Place of Presentation
  米国・サンフランシスコ(Moscone Center)
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Heterozygous Beta2-glycoprotein I Deficiency is a Risk for Antiphospholipid Syndrome and Hemolytic Anemia in SLE2008
- Author(s)
  Yasuda S, et.al.
- Organizer
  6th International congress of autoimmunity
- Place of Presentation
  ポルトガル・ボルト(コングレスセンター)
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] シンポジウム「SLE患者におけるRasGRP1発現の異常」2008
- Author(s)
  保田晋助
- Organizer
  第52回日本リウマチ学会学術総会
- Place of Presentation
  札幌(ロイトン札幌)
- Year and Date
  2008-04-22
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Heterozygous Beta2-Glycoprotein I Deficiency is a Risk Factor for Antiphospholipid Syndrome2008
- Author(s)
  Yasuda S, et.al.
- Organizer
  ヨーロッパリウマチ学会総会
- Place of Presentation
  フランス・パリ(Palais des congres)
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20591163
[Presentation] Altered expression of RasGRP4 in a Subset of Patients with Rheumatoid Arthritis.2007
- Author(s)
  Hashimoto T, Yasuda S, Kataoka H, Horita T, Atsumi T, Stevens R, Koike T.
- Organizer
  The Annual European Congress of Rheumatology
- Place of Presentation
  CCIB, Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-17689031
[Presentation] Phosphatidylserine dependent antiprothrombin antibody induces p38 mitogen-activated protein kinase (MAPK) phosphorylation leading to tissue fact or expression activated protein kinase (MAPK) phosphorylation leading to tissue factor expression.2007
- Author(s)
  Oku K, Atsumi T, Amengual O, Sakai Y, Kataoka H, Horita T, Yasuda S, Koike T
- Organizer
  12th International Congress on Antiphospholipid antibodies
- Place of Presentation
  Palazzo dei Congressi, Florence, Italy
- Data Source
  KAKENHI-PROJECT-17689031
[Presentation] Defective expression of Ras Guanine Nucleotide Releasing Protein 1 in a subset of patients with systemic lupus erythematosus.2007
- Author(s)
  Yasuda S, Stevens RL, Terada T, Horita T, Kataoka H, Fukae J, Hashimoto T, Atsumi T, Koike T
- Organizer
  American College of Rheumatology
- Place of Presentation
  Boston Convention Center, Boston, U.S.A.
- Data Source
  KAKENHI-PROJECT-17689031
[Presentation] Hemophagocytic syndrome in systemic lupus erythematosus.2007
- Author(s)
  Fukaya S, Yasuda S, Kataoka H, Horita T, Atsumi T, Koike T.
- Organizer
  The 8th International Congress on SLE
- Place of Presentation
  Shanghai International Convention Center, Shanghai, China
- Data Source
  KAKENHI-PROJECT-17689031

1. MATSUURA Eiji (20181688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SASAKI Takanori (10461253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KOBAYASHI Kazuko (20304298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKENAKA Fumiaki (10642522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OZEKI Eiichi (30192529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUJIWAKE Hideshi (50395696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOBUCHI Hirotsugu (10304297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 細矢匡 (60737104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKAHASHI Hidehisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. KATO Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 奥健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 渥美達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 小池隆夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 山本健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 笹月健彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 堀田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 酒井良子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasuda Shinsuke 保田 晋助

YASUDA Shinsuke 保田 晋助

Research Projects

Research Products

Co-Researchers

自然免疫および血管内皮障害に着目したSLE・APSの新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Amendment of abnormal RasGRP signaling in patients with systemic autoimmunityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism how RasGRP4 promotes proliferation of synovial fibroblasts in rheumatoid arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of Molecular Imaging and Lipidomics Technologies for Early Diagnosis of Atherosclerotic Disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of recombinant nicked beta2-glycoprotein I domain V in angiogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Abnormal expressions of RasGRPs in autoimmune diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アンギオスタチンを介したニックβ_2グリコプロテインIの血管新生に与える影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 顕微鏡的多発血管炎2012

Author(s)

Publisher

Data Source

[Book] 全身性エリテマトーデスに対する抗体治療–分子標的治療開発の道のりと現状, 別冊医学のあゆみ,抗体医薬Update–開発コンセプトから最新治療実績まで2012

Author(s)

Total Pages

Publisher

Data Source

[Book] 別冊医学のあゆみ, 抗体医薬 Update – 開発コンセプトから最新治療実績まで2012

Author(s)

Publisher

Data Source

[Book] 顕微鏡的多発血管炎, 膠原病の肺合併症診療マニュアル2012

Author(s)

Total Pages

Publisher

Data Source

[Book] 別冊日本臨床呼吸器症候群(第2版)II2009

Author(s)

Total Pages

Publisher

Data Source

[Book] よくわかる関節リウマチのすべて「関節リウマチとはどんな病気か」2009

Author(s)

Total Pages

Publisher

Data Source

[Book] よくわかる関節リウマチのすべて(「関節リウマチとはどんな病気か」)2009

Author(s)

Publisher

Data Source

[Book] 呼吸器症候群(第2版)(「原発性抗リン脂質抗体症候群」)(別冊日本臨床)2009

Yasuda Shinsuke 保田晋助

YASUDA Shinsuke 保田晋助