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Furumoto Shozo  古本 祥三

ORCIDConnect your ORCID iD *help
… Alternative Names

FURUMOTO Shozo  古本 祥三

古本 祥二  フルモト ショウゾウ

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Researcher Number 00375198
Other IDs
Affiliation (Current) 2025: 東北大学, 先端量子ビーム科学研究センター, 教授
Affiliation (based on the past Project Information) *help 2024: 東北大学, 先端量子ビーム科学研究センター, 教授
2014 – 2023: 東北大学, サイクロトロン・ラジオアイソトープセンター, 教授
2014: 東北大学, 学際科学フロンティア研究所, 准教授
2013 – 2014: 東北大学, サイクロトロン・ラジオアイソトープセンター, 准教授
2013: 東北大学, サイクロトロン・ラジオアイソトープセンター, 准教授 … More
2012: 東北大学, 大学院医学系研究科, 准教授
2011 – 2012: 東北大学, 医学(系)研究科(研究院), 准教授
2009 – 2012: Tohoku University, 大学院・医学系研究科, 准教授
2009: 東北大学, 大学院・医学系研究科, 講師
2008: 東北大学, 先進医学研究機構, 助教
2008: Tohoku University, 加齢医学研究所, 助教
2007: Tohoku University, 先進医工学研究機構, 助教
2005 – 2006: 東北大学, 先進医工学研究機構, 助手 Less
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 52:General internal medicine and related fields / Neurology / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 53:Organ-based internal medicine and related fields … More / Tumor therapeutics / Tumor diagnosis / Medical systems / Neurochemistry/Neuropharmacology Less
Keywords
Principal Investigator
PET / イメージング / フッ素18 / ホスホニウム / ミトコンドリア / 心筋血流 / 18F / 造影剤 / 放射性医薬品 / コンブレタスタチン … More / 低酸素 / FMISO / AVE8062 / イメージングプローブ / 原発性アルドステロン症 / アルドステロン産生腺腫 / CYP11B2 / 副腎腺腫 / トランスレーショナル / 18F標識トレーサー / 分子イメージング / PET / 心臓 / 心筋イメージング / PETイメージング / タウ / プローブ / タンパク質標識 / 無細胞タンパク質合成 / 無細胞タンパク質合成系 / リンパ節転移 / リンパ管新生 / VEGFR-3 / 心虚血 / 腫瘍 / MMP / 治療効果 / 薬物動態 / 腫瘍血流遮断 / 腫瘍血管 / 癌治療 … More
Except Principal Investigator
PET / 分子イメージング / アルツハイマー病 / パーキンソン病 / 自動合成 / 標識プローブ / 標識合成 / マイクロリアクター / 体動補正 / LAT1 / フッ素-18 / がん / α-シヌクレイン / [11C]BF-227 / 神経変性疾患 / 慢性低酸素 / オートファジー障害 / MRI / 鉄 / オートファジー / 認知症 / タウ / アストログリオーシス / モノアミン酸化酵素B (MAO-B) / 全身集積 / ポジトロン断層法(PET) / [18F]SMBT-1 / MAO阻害薬 / 腫瘍疾患 / 変性性神経疾患 / モノアミン酸化酵素(MAO-B) / ポジトロン断層法 (PET) / Amino acid metabolism / Breast cancer / Brain metastasis / 脳機能評価 / 小動物PET / アストロサイト / バイオマーカー / 神経炎症 / 生体機能 / 無麻酔 / 小動物 / 膵癌早期診断 / 細胞老化 / 膵癌 / アミノ酸トランスポーター / 薬剤耐性 / 化学療法 / 内分泌療法 / メタボローム解析 / ミトコンドリア代謝 / 化学療法耐性 / 内分泌療法耐性 / 食道癌 / ミトコンドリアダイナミクス / アミノ酸代謝 / 乳癌 / モノアミン酸化酵素B / グリオーシス / ミスフォールディング / ホスホニウム / ミトコンドリア / 腫瘍イメージング / [11C] BF-227 / 分子プローブ / マイクロリアクター合成 / ペプチドタンパク質標識 / メチオニン / PET診断プローブ / 癌 / バイオテクノロジー / 蛋白質 / トリフルオロメチル基 / 様式プローブ / PET / BPA / BNCT / F-18 BPA / パラボロノフェニルアラニン(BPA) / BNCT / 多系統萎縮症 / 超高分解能PET / 腫瘍血流遮断剤 / 腫瘍血流遮断 / 高分解能PET / 腫瘍血管遮断薬 / 粒子線治療 / 放射性薬剤 / F-18 / イメージング / α-シヌクレイン・イメージング / タウ・イメージング / アミロイド・イメージング / 脳内薬物動態 / マイクロドーズ / 分子標的治療薬 / 治療効果判定 / 分子標的治療 / ポジトロントレーサー / デオキシグルコース / デオキシマンノース / がん画像診断 / ^<18>F-フルオロデオキシグルコース / 求核置換反応 / 標識合成法 / ^<18>F-フルオロデオキシマンノース / 腫瘍イメージンダ / 画像診断学(含放射線診断学、核医学) / 低酸素細胞増感剤-抗癌剤リンク薬剤 / 放射線治療 / 低酸素細胞増感剤-抗癌剤ハイブリッド薬剤 / PET診断 / 放射線化学療法 / 低酸素細胞増感剤 Less
  • Research Projects

    (33 results)
  • Research Products

    (168 results)
  • Co-Researchers

    (58 People)
  •  フリームービング小動物PET検査が拓く脳基礎研究の新展開

    • Principal Investigator
      志田原 美保
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  Investigating the mechanisms for the development of brain metastases through LAT1 and suggesting potential therapeutic approaches.

    • Principal Investigator
      原田 成美
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Tohoku University
  •  新規分子骨格を基盤とした次世代PET用タウプローブの開発研究Principal Investigator

    • Principal Investigator
      古本 祥三
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  Elucidation of the pathophysiology of Alzheimer's disease by a novel tau-specific PET tracer, [F18]SNFT-1

    • Principal Investigator
      金田 朋洋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  認知症におけるオートファジー障害の病態解明とPADREによる超早期画像診断法の開発

    • Principal Investigator
      瀧 靖之
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  Development of a CYP11B2 probe for imaging aldosterone-producing adenomas with high sensitivity.Principal Investigator

    • Principal Investigator
      古本 祥三
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  神経炎症を生体画像化する新規画像バイオマーカーの開発研究

    • Principal Investigator
      岡村 信行
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tohoku Medical and Pharmaceutical University
  •  Non-anesthetic, non-restraining evaluation of biological functions in animal PET with motion correction for multiple individuals

    • Principal Investigator
      Shidahara Miho
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tohoku University
  •  Quantitative MAO-B imaging of human brain and whole-body organs using [18F]SMBT-1 PET

    • Principal Investigator
      田代 学
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  Identification of new therapeutic targets for glucose independent metabolism in breast cancer

    • Principal Investigator
      Narumi Harada
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Tohoku University
  •  Development of hybrid PET probe for early detection of pancreatic cancer

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Tohoku University
  •  Development of protein-specific PET molecular imaging in neurodegenerative disorders

    • Principal Investigator
      Yanai Kazuhiko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tohoku University
  •  Translational research of a 18F-labeled cation type myocardium perfusion imaging agentPrincipal Investigator

    • Principal Investigator
      Furumoto Shozo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tohoku University
  •  Development of a high-concentrated [11C]methionine automated synthesizer for cell-free synthesis of 11C-labeled proteins

    • Principal Investigator
      ISHIKAWA Yoichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Development of a practical myocardial blood flow imaging agent based on novel F18-labeled phosphonium synthesis methodPrincipal Investigator

    • Principal Investigator
      Furumoto Shozo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Development of 18F-labelled phosphonium derivatives for tumor imaging

    • Principal Investigator
      Tominaga Takahiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Radiation science
    • Research Institution
      Southen Tohoku Research Institute for Neuroscience
  •  Innovative cancer-specific structural conversion design into high functional small bispecific antibodies

    • Principal Investigator
      Asano Ryutaro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  In vivo visualization of synuclein deposits in Parkinson's disease and its clinical applicability

    • Principal Investigator
      Kikuchi Akio
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Development of a multipurpose microreactor system for preparation of 18F-labeled probes

    • Principal Investigator
      Iwata Ren
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Precise evaluation and optimization of the THK probe for tau imagingPrincipal Investigator

    • Principal Investigator
      FURUMOTO SHOZO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  A new extended library of 18F-labeled probes: Synthesis and use of [18F]CF3Br

    • Principal Investigator
      IWATA Ren
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Novel ion-beam therapy technology combined with a vascular disrupting agent based on assessment of treatment effects using a high-resolution PET

    • Principal Investigator
      TERAKAWA Atsuki
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Medical systems
    • Research Institution
      Tohoku University
  •  In vivo visualization of synuclein deposition in multiple system atrophy and its clinical applicability

    • Principal Investigator
      KIKUCHI Akio
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Development of positron emitter labeled agents for boron neutron capture therapy

    • Principal Investigator
      FUKUDA Hiroshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnosis
    • Research Institution
      Tohoku University
  •  Novel synthetic approach for a positron emitter labeled protein by cell free protein synthesis systemPrincipal Investigator

    • Principal Investigator
      FURUMOTO Shozo
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Development of a total microreactor system for radiosynthesis of^<18>F-labeled PET probes

    • Principal Investigator
      IWATA Ren
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  神経創薬に応用可能な神経イメージング基技術の萌芽的開発

    • Principal Investigator
      Yanai Kazuhiko
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tohoku University
  •  Development of a VEGFR3 imaging agent by PET for predictive diagnosis of lymph node metastasis.Principal Investigator

    • Principal Investigator
      FURUMOTO Shozo
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  In vivo study to utilize Positron Emission Tomography for evaluating the indication and efficacy of molecular targeted agents.

    • Principal Investigator
      YOSHIOKA Takashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Yamagata University
  •  Development of F-18 fluorodeoxymannose (FDM) as a PET probe for cancer imaging

    • Principal Investigator
      FUKUDA Hiroshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Molecular imaging of Matrix Metalloproteinase related to pathology of hypoxiaPrincipal Investigator

    • Principal Investigator
      FURUMOTO Shozo
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  低酸素細胞増感剤を応用した新抗癌剤デリバリーシステムを用いた化学放射線療法の開発

    • Principal Investigator
      高井 良尋
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  PETによる腫瘍血流遮断薬の臨床評価法開発に関する基盤研究Principal Investigator

    • Principal Investigator
      古本 祥三
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] 非侵襲・可視化技術ハンドブックーナノ・バイオ・医療から情報システムまで-(小川誠二、上野照剛監修)2007

    • Author(s)
      工藤幸司、古本祥三, 他
    • Publisher
      エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Journal Article] The neuromodulatory role of dopamine in improved reaction time by acute cardiovascular exercise.2024

    • Author(s)
      Ando S, Fujimoto T, Sudo M, Watanuki S, Hiraoka K, Takeda K, Takagi Y, Kitajima D, Mochizuki K, Matsuura K, Katagiri Y, Nasir FM, Lin Y, Fujibayashi M, Costello JT, McMorris T, Ishikawa Y, Funaki Y, Furumoto S, Watabe H, Tashiro M.
    • Journal Title

      J Physiol.

      Volume: 602 Issue: 3 Pages: 461-484

    • DOI

      10.1113/jp285173

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21420, KAKENHI-PROJECT-23K24750
  • [Journal Article] 2.Amyloid accumulation in cases of suspected comorbid cerebral amyloid angiopathy and isolated cortical venous thrombosis.2024

    • Author(s)
      Kobayashi Y, Hiraoka K, Itabashi R, Saito T, Kawabata Y, Yazawa Y, Funaki Y, Furumoto S, Okamura N, Furukawa K, Ishiki A, Arai H, Yanai K, Tashiro M, Sekijima Y.
    • Journal Title

      J Neurol Sci

      Volume: 15 Pages: 122892-122892

    • DOI

      10.1016/j.jns.2024.122892

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15647, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-23K07069, KAKENHI-PROJECT-23K21420
  • [Journal Article] A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer’s Disease Mouse Model2023

    • Author(s)
      Naganuma Fumito、Murata Daiki、Inoue Marie、Maehori Yuri、Harada Ryuichi、Furumoto Shozo、Kudo Yukitsuka、Nakamura Tadaho、Okamura Nobuyuki
    • Journal Title

      Molecular Imaging and Biology

      Volume: 25 Issue: 6 Pages: 1115-1124

    • DOI

      10.1007/s11307-023-01843-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-22K07373, KAKENHI-PROJECT-23K07069, KAKENHI-PROJECT-23K08342, KAKENHI-PROJECT-23K24070
  • [Journal Article] In vivo [18F]THK-5351 imaging detected reactive astrogliosis in argyrophilic grain disease with comorbid pathology: A clinicopathological study2023

    • Author(s)
      Ryota Kobayashi , Tadaho Nakamura, Fumito Naganuma, Ryuichi Harada, Daichi Morioka, Masafumi Kanoto, Shozo Furumoto, Yukitsuka Kudo, Takanobu Kabasawa, Koichi Otani, Mitsuru Futakuchi , Shinobu Kawakatsu, Nobuyuki Okamura
    • Journal Title

      J Neuropathol Exp Neurol .

      Volume: - Issue: 5 Pages: 427-437

    • DOI

      10.1093/jnen/nlad018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-22K07373, KAKENHI-PROJECT-22K07552, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K07922, KAKENHI-PROJECT-20K09204, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-23K06646, KAKENHI-PROJECT-23K07129, KAKENHI-PROJECT-20K07619
  • [Journal Article] Evaluation of 18F labeled glial fibrillary acidic protein binding nanobody and its brain shuttle peptide fusion proteins using a neuroinflammation rat model2023

    • Author(s)
      Morito Takahiro、Harada Ryuichi、Iwata Ren、Ishikawa Yoichi、Okamura Nobuyuki、Kudo Yukitsuka、Furumoto Shozo、Yanai Kazuhiko、Tashiro Manabu
    • Journal Title

      PLOS ONE

      Volume: 18 Issue: 6 Pages: 0287047-0287047

    • DOI

      10.1371/journal.pone.0287047

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-23K07069, KAKENHI-PROJECT-21K19320, KAKENHI-PROJECT-23K21420, KAKENHI-PROJECT-23K24070
  • [Journal Article] Assessing reactive astrogliosis with 18F-SMBT-1 across the Alzheimer’s disease spectrum2022

    • Author(s)
      Villemagne Victor L、Harada Ryuichi、Dore Vincent、Furumoto Shozo、Mulligan Rachel、Kudo Yukitsuka、Burnham Samantha、Krishnadas Natasha、Bourgeat Pierrick、Xia Ying、Laws Simon、Bozinovski Svetlana、Huang Kun、Ikonomovic Milos D、Fripp Jurgen、Yanai Kazuhiko、Okamura Nobuyuki、Rowe Christopher C
    • Journal Title

      Journal of Nuclear Medicine

      Volume: - Issue: 10 Pages: 1560-1569

    • DOI

      10.2967/jnumed.121.263255

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-18H02771
  • [Journal Article] Imaging of Reactive Astrogliosis by Positron Emission Tomography2022

    • Author(s)
      Harada Ryuichi、Furumoto Shozo、Kudo Yukitsuka、Yanai Kazuhiko、Villemagne Victor L.、Okamura Nobuyuki
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 807435-807435

    • DOI

      10.3389/fnins.2022.807435

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-23K21420, KAKENHI-PROJECT-23K24070
  • [Journal Article] The Role of Chirality of [<sup>18</sup>F]SMBT-1 in Imaging of Monoamine Oxidase-B2022

    • Author(s)
      Harada Ryuichi、Shimizu Yuki、Du Yiqing、Ishikawa Yoichi、Iwata Ren、Kudo Yukitsuka、Yanai Kazuhiko、Okamura Nobuyuki、Furumoto Shozo
    • Journal Title

      ACS Chemical Neuroscience

      Volume: 13 Issue: 3 Pages: 322-329

    • DOI

      10.1021/acschemneuro.1c00655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-23K21420
  • [Journal Article] First-in-human evaluation of <sup>18</sup>F-SMBT-1, a novel <sup>18</sup>F-labeled MAO-B PET tracer for imaging reactive astrogliosis2022

    • Author(s)
      Villemagne Victor L、Harada Ryuichi、Dore Vincent、Furumoto Shozo、Mulligan Rachel、Kudo Yukitsuka、Burnham Samantha、Krishnadas Natasha、Bozinovski Svetlana、Huang Kun、Lopresti Brian J、Yanai Kazuhiko、Rowe Christopher C、Okamura Nobuyuki
    • Journal Title

      Journal of Nuclear Medicine

      Volume: - Issue: 10 Pages: 1551-1559

    • DOI

      10.2967/jnumed.121.263254

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-22KK0123, KAKENHI-PROJECT-18H02771
  • [Journal Article] L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism2021

    • Author(s)
      Sato Miku、Harada-Shoji Narumi、Toyohara Takafumi、Soga Tomoyoshi、Itoh Masatoshi、Miyashita Minoru、Tada Hiroshi、Amari Masakazu、Anzai Naohiko、Furumoto Shozo、Abe Takaaki、Suzuki Takashi、Ishida Takanori、Sasano Hironobu
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 589-589

    • DOI

      10.1038/s41598-020-80668-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08948, KAKENHI-PROJECT-19K23933, KAKENHI-PROJECT-19K09065
  • [Journal Article] Targeting amino acid metabolic reprogramming via l-type amino acid transporter 1 (Lat1) for endocrine-resistant breast cancer2021

    • Author(s)
      Haruhiko Shindo, Narumi Harada-Shoji, Akiko Ebata, Miku Sato, Tomoyoshi Soga, Minoru Miyashita, Hiroshi Tada, Masaaki Kawai, Shinkichi Kosaka, Koji Onuki, Shin Usami, Shozo Furumoto, Shinichi Hayashi, Takaaki Abe, Takashi Suzuki, Takanori Ishida, Hironobu Sasano
    • Journal Title

      Cancers

      Volume: 13 Pages: 4375-4375

    • Data Source
      KAKENHI-PROJECT-19H03595
  • [Journal Article] L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism2021

    • Author(s)
      Miku Sato, Narumi Harada-Shoji, Takafumi Toyohara, Tomoyoshi Soga, Masatoshi Itoh, Minoru Miyashita, Hiroshi Tada, Masakazu Amari, Naohiko Anzai, Shozo Furumoto, Takaaki Abe, Takashi Suzuki, Takanori Ishida, Hironobu Sasano
    • Journal Title

      Scientific reports

      Volume: 11 Pages: 1-1

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19H03595
  • [Journal Article] Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer2021

    • Author(s)
      Shindo Haruhiko、Harada-Shoji Narumi、Ebata Akiko、Sato Miku、Soga Tomoyoshi、Miyashita Minoru、Tada Hiroshi、Kawai Masaaki、Kosaka Shinkichi、Onuki Koji、Usami Shin、Furumoto Shozo、Hayashi Shinichi、Abe Takaaki、Suzuki Takashi、Ishida Takanori、Sasano Hironobu
    • Journal Title

      Cancers

      Volume: 13 Issue: 17 Pages: 4375-4375

    • DOI

      10.3390/cancers13174375

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-19K09109, KAKENHI-PROJECT-20K08948
  • [Journal Article] Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle2021

    • Author(s)
      Jing Liu, Yunhua Peng, LE Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long, Jianping Guo, Jinfang Zhang, Min Yuan, Shuangxi Zhang, Xun Wang, Jing Gao, Xiangpeng Dai, Shozo Furumoto, Lijun Jia, Pier Paolo Pandolfi, John M Asara, William G Kaelin, Jiankang Liu, Wenyi Wei
    • Journal Title

      Cell research

      Volume: 31 Pages: 80-93

    • Data Source
      KAKENHI-PROJECT-19H03595
  • [Journal Article] 18F-THK5351 PET imaging in neurodegenerative tauopathies2021

    • Author(s)
      Ezura M, Kikuchi A, Okamura N, Ishiki A, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Ishiyama S, Nakamura T, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
    • Journal Title

      Front Aging Neurosci

      Volume: 13 Pages: 761010-761010

    • DOI

      10.3389/fnagi.2021.761010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-20K07830, KAKENHI-PROJECT-20K07862, KAKENHI-PROJECT-20K07879, KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-21K19320, KAKENHI-PROJECT-18K15357, KAKENHI-PROJECT-19KK0212
  • [Journal Article] 18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging2020

    • Author(s)
      Harada Ryuichi、Hayakawa Yoshimi、Ezura Michinori、Lerdsirisuk Pradith、Du Yiqing、Ishikawa Yoichi、Iwata Ren、Shidahara Miho、Ishiki Aiko、Kikuchi Akio、Arai Hiroyuki、Kudo Yukitsuka、Yanai Kazuhiko、Furumoto Shozo、Okamura Nobuyuki
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 62 Issue: 2 Pages: 253-258

    • DOI

      10.2967/jnumed.120.244400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08043, KAKENHI-PROJECT-18K15357, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-20H03614, KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-20K07879
  • [Journal Article] Longitudinal changes in 18F-THK5351 PET in corticobasal syndrome2019

    • Author(s)
      Ezura M, Kikuchi A, Ishiki A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Kobayashi M, Tano O, Nakashima I, Mugikura S, Iwata R, Taki Y, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
    • Journal Title

      Eur J Neurol

      Volume: 26 Issue: 9 Pages: 1205-1211

    • DOI

      10.1111/ene.13966

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-17K20083, KAKENHI-PROJECT-19KK0212, KAKENHI-PROJECT-16H05385, KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-18K15538, KAKENHI-PROJECT-18H02771
  • [Journal Article] Structure-Activity Relationship of 2-Arylquinolines as PET Imaging Tracers for Tau Pathology in Alzheimer’s Disease2016

    • Author(s)
      Tetsuro Tago, Shozo Furumoto, Nobuyuki Okamura, Ryuichi Harada, Hajime Adachi, Yoichi Ishikawa, Kazuhiko Yanai, Ren Iwata, and Yukitsuka Kudo
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 57(4) Issue: 4 Pages: 608-614

    • DOI

      10.2967/jnumed.115.166652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-16H05383, KAKENHI-PROJECT-16K15570
  • [Journal Article] In vivo visualization of tau pathology using 18F-THK5351 PET in corticobasal syndrome.2016

    • Author(s)
      Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Kobayashi M, Tano O, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Hiraoka K, Mugikura S, Takase K, Iwata R, Taki Y, Furukawa K, HArai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A,Aoki M.
    • Journal Title

      Neurology

      Volume: 87 Issue: 22 Pages: 2309-2316

    • DOI

      10.1212/wnl.0000000000003375

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01550, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-15K19767, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-16K15570
  • [Journal Article] Radiosynthesis and preliminary biological evaluation of a new 18F-labeled triethylene glycol derivative of triphenylphosphonium.2016

    • Author(s)
      Y., Iwata R., Ishikawa K., Furumoto S.
    • Journal Title

      J. Label. Compd. Radiopharm.

      Volume: 59 Issue: 3 Pages: 117-123

    • DOI

      10.1002/jlcr.3379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05383, KAKENHI-PROJECT-16K10267
  • [Journal Article] 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease2016

    • Author(s)
      Harada R, Okamura N, Furumoto S, Furukawa K, Ishiki A, Tomita N, Tago T, Hiraoka K, Watanuki S, Shidahara M, Miyake M, Ishikawa Y, Matsuda R, Inami A, Yoshikawa T, Funaki Y, Iwata R, Tashiro M, Yanai K, Arai H, Kudo Y
    • Journal Title

      J Nucl Med

      Volume: 57 Issue: 2 Pages: 208-214

    • DOI

      10.2967/jnumed.115.164848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08127, KAKENHI-PROJECT-15K15268, KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-25670525, KAKENHI-PROJECT-26830041, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-16H05383
  • [Journal Article] Preclinical evaluation of [18F]THK-5015 enantiomers: effects of chirality on its effectiveness as a tau imaging radiotracer.2015

    • Author(s)
      Tago T., Furumoto S., Okamura N., Harada R., Adachi H., Ishikawa Y., Yanai K., Iwata R., Kudo Y.
    • Journal Title

      Mol. Imaging Biol.

      Volume: 未定 Issue: 2 Pages: 258-266

    • DOI

      10.1007/s11307-015-0879-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15444, KAKENHI-PROJECT-15K19767, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-14J06908, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-15H04900
  • [Journal Article] Quantitative kinetic analysis of PET amyloid imaging agents [(11)C]BF227 and [(18)F]FACT in human brain.2015

    • Author(s)
      Shidahara M, Watabe H, Tashiro M, Okamura N, Furumoto S, Watanuki S, Furukawa K, Arakawa Y, Funaki Y, Iwata R, Gonda K, Kudo Y, Arai H, Ishiwata K, Yanai K.
    • Journal Title

      Nucl Med Biol.

      Volume: 42 Issue: 9 Pages: 734-744

    • DOI

      10.1016/j.nucmedbio.2015.05.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15268, KAKENHI-PROJECT-15K15444, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-25670525, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-26293133
  • [Journal Article] 18F標識PETプローブの現状と展望2014

    • Author(s)
      古本祥三
    • Journal Title

      INNERVISION

      Volume: 29 Pages: 11-14

    • Data Source
      KAKENHI-PROJECT-25293259
  • [Journal Article] Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging2014

    • Author(s)
      Tetsuro Tago, Shozo Furumoto, Nobuyuki Okamura, Ryuichi Harada, Yoichi Ishikawa, Hiroyuki Arai, Kazuhiko Yanai, Ren Iwata, Yhkitsuka Kudo
    • Journal Title

      Journal of Labelled Compounds and Radiopharmaceuticals

      Volume: 57 Issue: 1 Pages: 18-24

    • DOI

      10.1002/jlcr.3133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07785, KAKENHI-PROJECT-23390297, KAKENHI-PROJECT-24659255, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-25461870, KAKENHI-PROJECT-25670523, KAKENHI-PROJECT-25670524
  • [Journal Article] Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.2014

    • Author(s)
      Nobuyuki Okamura, Shozo Furumoto, Michelle T. Fodero-Tavoletti, Rachel S. Mulligan, Ryuichi Harada, Paul Yates, Svetlana Pejoska, Yukitsuka Kudo, Colin L. Masters, Kazuhiko Yanai, Christopher C. Rowe, Victor L. Villemagne
    • Journal Title

      Brain

      Volume: 137 Pages: 1762-1771

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Journal Article] [18F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.2014

    • Author(s)
      Harada R, Furukawa K, et al.
    • Journal Title

      Eur J Nucl Med Mol Imaging

      Volume: 42 Issue: 7 Pages: 1052-1061

    • DOI

      10.1007/s00259-015-3035-4

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390179, KAKENHI-PROJECT-15K15268, KAKENHI-PROJECT-15K15444, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-25670525, KAKENHI-PROJECT-26830041, KAKENHI-PROJECT-25293257
  • [Journal Article] Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.2014

    • Author(s)
      Okamura N, Furumoto S, Fodero-Tavoletti MT, Mulligan RS, Harada R, Yates P, Pejoska S, Kudo Y, Masters CL, Yanai K, Rowe CC, Villemagne VL.
    • Journal Title

      Brain

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Journal Article] Analysis of early phase [11C]BF-227 PET, and its application for anatomical standardization of late-phase images for 3D-SSP analysis.2014

    • Author(s)
      Kaneta T., Okamura N., Arai A., Takanami K., Furukawa K., Tashiro M., Furumoto S., Iwata R., Takahashi S., Arai H., Yanai K., Kudo Y.
    • Journal Title

      Jpn. J. Radiol.

      Volume: 32 Pages: 138-144

    • NAID

      50009030775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293257
  • [Journal Article] タウプローブ開発の最先端2014

    • Author(s)
      古本 祥三, 岡村 信行, 原田 龍一, 多胡 哲朗, 工藤 幸司
    • Journal Title

      JSMI Report

      Volume: 8 Pages: 3-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Journal Article] In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease2014

    • Author(s)
      Villemagne L. Victor, Shozo Furumoto, Michelle T. Fodero-Tavoletti, Rachel S. Mulligan, John Hodges, Ryuichi Harada, Paul Yates, Oliver Piguet, Svetlana Pejoska, Vincent Doré, Kazuhiko Yanai, Colin L. Masters, Yukitsuka Kudo, Christopher C. Rowe, Nobuyuki Okamura.
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: 41 Issue: 5 Pages: 816-826

    • DOI

      10.1007/s00259-013-2681-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J07785, KAKENHI-PROJECT-23390297, KAKENHI-PROJECT-24659255, KAKENHI-PROJECT-25293259, KAKENHI-PROJECT-25670524, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016
  • [Journal Article] In vitro and in vivo characterization of 2-Deoxy-2- [^<18>F]Fluoro-D-Mannose as a tumor- imaging agent for positron emission tomography2013

    • Author(s)
      Furumoto S, Shinbo R, Iwata R, Ishikawa R, Yanai K, Yoshioka T, Fukuda H
    • Journal Title

      J. Nucl. Med.

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Evaluation of the biodistribution and radiation dosimetry of the ^(11)F-labelled amyloid imaging probe [^(18)F]F ACT in humans2013

    • Author(s)
      Shidahara M, Tashiro M, Okamura N, Furumoto S, Furukawa K, Watanuki S, Hiraoka K, Miyake M, Iwata R, Tamura H, Arai H, Kudo Y, Y anai K
    • Journal Title

      EJNMMI Res

      Volume: 3 Issue: 1 Pages: 32-32

    • DOI

      10.1186/2191-219x-3-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390297, KAKENHI-PROJECT-24659255, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-25670525, KAKENHI-PROJECT-25861059
  • [Journal Article] In vitro and in vivo characterization of 2-Deoxy-2-[18F]Fluoro-D-Mannose as a tumor-imaging agent for positron emission tomography2013

    • Author(s)
      Furumoto S
    • Journal Title

      J. Nucl. Med.

      Volume: accepted

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Novel 18F-labeled arylquinoline derivatives for non-invasive imaging of tau pathology inAlzheimer’s disease.2013

    • Author(s)
      Okamura N., Furumoto S., Harada R., Tago T., Yoshikawa T., Fodero-Tavoletti M., Mulligan R.S., Villemagne V.L., Akatsu H., Yamamoto T., Arai H., Iwata R., Yanai K., Kudo Y
    • Journal Title

      Nucl. Med. Mol. Imag.

      Volume: 54 Pages: 1420-1427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293257
  • [Journal Article] In vitro and vivo characterization of 2-Deoxy-2-〔18F〕Fluoro-D-Mannose as a tumor-imaging agent for positron emission tomography2013

    • Author(s)
      Furumoto S, Shinbo R, Iwata R, Ishikawa Y, Ynai K, Yoshioka T, Fukuda H
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 54 Issue: 8 Pages: 1354-1361

    • DOI

      10.2967/jnumed.112.113571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300345, KAKENHI-PROJECT-24659255, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-25461870, KAKENHI-PROJECT-25670523
  • [Journal Article] A ^<18>F-Labeled BF-227 derivative as a potential radioligand for imaging dense amyloid plaques by positron emission tomography2013

    • Author(s)
      Shozo Furumoto
    • Journal Title

      Molecular Imaging and Biology

      Volume: 15 Issue: 4 Pages: 497-506

    • DOI

      10.1007/s11307-012-0608-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07785, KAKENHI-PROJECT-23390297, KAKENHI-PROJECT-24659255, KAKENHI-PROJECT-25293257, KAKENHI-PROJECT-25461870, KAKENHI-PROJECT-25670523, KAKENHI-PROJECT-25670524, KAKENHI-PROJECT-25670525
  • [Journal Article] Reactivity of electrochemically concentrated anhydrous [^<18>F]Fluoride formicrofluidic radiosynthesis of 18F-labeled compounds2012

    • Author(s)
      Wong R, Iwata R, Saiki H, Furumoto S, Ishikawa Y, Ozeki E.
    • Journal Title

      Appl. Radiat. Isot

      Volume: 70 Pages: 193-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Synthesis of [^<11>C]interleukin 8 using a cell-free translation system and L-[^<11>C] methionine2012

    • Author(s)
      Harada R, Furumoto S, Yoshikawa T, Ishikawa Y, Shibuya K, Okamura N, Iwata R, Yanai K.
    • Journal Title

      Nucl. Med. Biol

      Volume: 39 Pages: 155-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Rapid biochemical synthesis of (11)C-labeled single chain variable fragment antibody for immuno-PET by cell-free protein synthesis2012

    • Author(s)
      Matsuda T, Furumoto S, Higuchi K, Yokoyama J, Zhang MR, Yanai K, Iwata R, Kigawa T.
    • Journal Title

      Bioorg Med Chem

      Volume: 20(22) Pages: 6579-6582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791387
  • [Journal Article] Rapid biochemical synthesis of ^<11>C-labeled single chain variable fragmentantibody for immuno-PET by cell-free protein synthesis2012

    • Author(s)
      Matsuda T., Furumoto S., Higuchia K., Yokoyama J., Zhang M.-R., Yanai K., Iwatad R., Kigawa T.
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 20 Issue: 22 Pages: 6579-6582

    • DOI

      10.1016/j.bmc.2012.09.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228, KAKENHI-PROJECT-23791387, KAKENHI-PROJECT-24659255, KAKENHI-PLANNED-23119005
  • [Journal Article] Clairvivo PETを用いた小動物PET研究の実際2012

    • Author(s)
      古本祥三,田代学,岩田錬,谷内一彦
    • Journal Title

      RadFan

      Volume: 10 Pages: 59-62

    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Reactivity of electrochemically concentrated anhydrous [^<18>F]fluoride for microfluidic radiosynthesis of ^<18>F-labeled compounds2012

    • Author(s)
      Wong R., Iwata R., Saiki H., Furumoto S., Ishikawa Y., Ozeki E.
    • Journal Title

      Appl. Radiat. Isot

      Volume: 70 Issue: 1 Pages: 193-199

    • DOI

      10.1016/j.apradiso.2011.09.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228, KAKENHI-PROJECT-23650610, KAKENHI-PROJECT-23791387
  • [Journal Article] Synthesis of [^(11)C]interleukin 8 using a cell-free translation system and l-[^(11)C]methionine2012

    • Author(s)
      Harada R, Furumoto S, Y oshikawa T, Ishikawa Y, Shibuya K, Okamura N, Iwata R, Y anai K
    • Journal Title

      Nucl Med Biol

      Volume: 39 Issue: 1 Pages: 155-160

    • DOI

      10.1016/j.nucmedbio.2011.07.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390297, KAKENHI-PROJECT-23650610, KAKENHI-PROJECT-23791387, KAKENHI-PROJECT-24659255
  • [Journal Article] Rapid biochemical synthesis of ^<11>C-labeled single chain variable fragment antibody forimmuno-PET by cell-free protein synthesis2012

    • Author(s)
      Matsuda T, Furumoto S, Higuchia K, Yokoyama J, Zhang M-R, Yanai K, Iwata R, Kigawa T.
    • Journal Title

      Bioorg. Med. Chem

      Volume: 20 Pages: 6579-6582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Reactivity of Electrochemically Concentrated Anhydrous [^<18>p]Fluoride for Microfluidic Radiosynthesis of 18F-labeled Compounds2012

    • Author(s)
      Wong R., Iwata R., Saiki H., Furumoto S., Ishikawa Y., Ozeki E
    • Journal Title

      Appl.Radiat.Isot.

      Volume: 70 Pages: 193-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Journal Article] Clairvivo PETを用いた小動物PET研究の実際.2012

    • Author(s)
      古本祥三
    • Journal Title

      RadFan

      Volume: 10(12) Pages: 59-62

    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] Synthesis of [^<11>C]interleukin 8 using a cell-free translation system and L-[^<11>C]methionine2012

    • Author(s)
      Harada R., Furumoto S., Yoshikawa T., Ishikawa Y., Shibuya K., Okamura N., Iwata R., Yanai K.
    • Journal Title

      Nucl.Med.Biol.

      Volume: 39 Pages: 155-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Journal Article] Reactivity of electrochemically concentrated anhydrous [^<18>F]fluoride for microfluidic radiosynthesis of ^<18>F-labeled compounds2012

    • Author(s)
      Wong R, Iwata R, Saiki H, Furumoto S, Ishikawa Y, Ozeki E.
    • Journal Title

      Appl Radiat Isot

      Volume: 70(1) Pages: 193-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791387
  • [Journal Article] Synthesis of [^<11>C]interleukin 8 using a cell-free translation system and L-[^<11>C]methionine2012

    • Author(s)
      Harada R, Furumoto S, Yoshikawa T, Ishikawa Y, Shibuya K, Okamura N, Iwata R, Yanai K.
    • Journal Title

      Nucl Med Biol

      Volume: 39(1) Pages: 155-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791387
  • [Journal Article] Synthesis of [^<11>C]interleukin 8 using a cell-freetranslation system and L-[^<11>C]methionine2012

    • Author(s)
      Harada R., Furumoto S., Yoshikawa T., Ishikawa Y., Shibuya K., Okamura N., Iwata R., Yanai K
    • Journal Title

      Nucl. Med. Biol

      Volume: 39 Pages: 155-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Journal Article] 【分子イメージング薬剤の標的選択的動態制御】薬物動態評価のPET分子イメージング2011

    • Author(s)
      古本祥三,谷内一彦
    • Journal Title

      Drug Delivery System

      Volume: 26 Pages: 401-409

    • NAID

      130001274712

    • Data Source
      KAKENHI-PROJECT-23650610
  • [Journal Article] A modified method of 3D-SSP analysis for amyloid PET imaging using [^<11>C]BF-2272011

    • Author(s)
      Kaneta T, Okamuia N, Minoshima S, Furukawa K, Tashiro M, Furumoto S, Iwata R, Fukuda H, Takahashi S, Yanai K, Kudo Y, Arai H
    • Journal Title

      Ann Nucl Med.

      Volume: 25 Issue: 10 Pages: 643-649

    • DOI

      10.1007/s12149-011-0518-7

    • NAID

      10030233510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590754, KAKENHI-PROJECT-22390228, KAKENHI-PROJECT-23390297
  • [Journal Article] 画像バイオマーカーとしての分子イメージングの利用:分子イメージングによる受容体占拠率の解析2010

    • Author(s)
      谷内一彦、吉川雄朗、古本祥三
    • Journal Title

      「創薬研究への分子イメージング応用」遺伝子MOOK18(佐治英郎編集メデイカルドゥ)

      Volume: 18 Pages: 133-139

    • Data Source
      KAKENHI-PROJECT-21650088
  • [Journal Article] Electrochemical concentration of no-carrier-added[(18)F]fluoride from[(18)O]water in a disposable microfluidic cell for radiosynthesis of (18)F-labeled radiopharmaceuticals2010

    • Author(s)
      Saiki H, Iwata R, Nakanishi H, Wong R, Ishikawa Y, Furumoto S, Yamahara R, Sakamoto K, Ozeki E
    • Journal Title

      Applied radiation and isotopes (未定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791168
  • [Journal Article] Electrochemical concentration ofno-carrier-added [^<18>F]fluoride from [18O]water in a disposable microfluidic cell for radiosynthesis of ^<18>F-labeled radiopharmaceuticals2010

    • Author(s)
      Saiki H., Iwata R., Nakanishi H., Wong R., Ishikawa Y., Furumoto S., Yamahara, R. Sakamoto K., Ozeki E
    • Journal Title

      Appl. Radiat. Isot

      Volume: 68 Issue: 9 Pages: 1703-1708

    • DOI

      10.1016/j.apradiso.2010.02.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Journal Article] Electrochemical Concentration of No-carrier-added [^<18>F]Fluoride from [^<18>O]Water in a Disposable Microfluidic Cell for Radiosynthesis of ^<18>F-labeled Radiopharmaceuticals2010

    • Author(s)
      H.Saiki, R.Iwata, H.Nakanishi, R.Wong, Y.Ishikawa, S.Furumoto, R.Yamahara, K.Sakamoto, E.Ozeki
    • Journal Title

      Appl.Radiat.Isot.

      Volume: 68 Pages: 1703-1708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Journal Article] Electrochemical concentration of no-carrier-added [(18)F]fluoride from [(18)O] water in a disposable microfluidic cell for radiosynthesis of (18)F-labeled radiopharmaceuticals.2010

    • Author(s)
      Saiki H, Iwata R, Nakanishi H, Wong R, Ishikawa Y, Furumoto S, Yamahara R, Sakamoto K, Ozeki E.
    • Journal Title

      Appl Radiat Isot. 68(9)

      Pages: 1703-1708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791168
  • [Journal Article] Tumor blood flow interruption after radiotherapy strongly inhibits tumor regrowth.2008

    • Author(s)
      Hori K, Furumoto S, Kubota K
    • Journal Title

      Cancer Sci 99

      Pages: 1485-1491

    • NAID

      10024009085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Journal Article] Assessment of tumor hypoxia induced by vascular targeting therapy.2007

    • Author(s)
      S.Furumoto, Hori K, Honda Y, Yoshioka T, Yamaura G, Ishikawa Y, Kubota K, Fukuda H, Kudo Y, Iwata R
    • Journal Title

      Journal of Nuclear Medicine 48(S2)

      Pages: 76-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Journal Article] Recent Advances in the Development of Amyloid Imaging Agents.2007

    • Author(s)
      Furumoto S, 他
    • Journal Title

      Current Topics in Medicinal Chemistry 7

      Pages: 1173-1789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Patent] PHOSPHONIUM COMPOUND AND PRODUCTION METHOD THEREFOR2017

    • Inventor(s)
      Shozo FURUMOTO
    • Industrial Property Rights Holder
      TOHOKU UNIVERSITY
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Patent] ポジトロン標識たんぱく質の合成方法2009

    • Inventor(s)
      谷内一彦、岩田錬、加藤元久、大貫哲也、古本祥三
    • Industrial Property Rights Holder
      谷内一彦、岩田錬、加藤元久、大貫哲也、古本祥三
    • Industrial Property Number
      2009-116379
    • Filing Date
      2009-05-25
    • Data Source
      KAKENHI-PROJECT-21650088
  • [Presentation] Analysis of [18F]SMBT-1 binding to reactive astrogliosis in postmortem brain tissues from patients with Alzheimer's disease and frontotemporal lobar degeneration.2023

    • Author(s)
      Okamura N, Harada R, Du Y, Yokoyama Y, Kudo Y, Tashiro M, Furumoto S.
    • Organizer
      SNMMI 2023 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0123
  • [Presentation] 神経炎症の画像化を目的としたPET薬剤の結合性の比較.2023

    • Author(s)
      原田 龍一, 工藤 楓, 石川 洋一, 岩田 錬, 工藤 幸司, 田代 学, 古本 祥三, 岡村 信行.
    • Organizer
      日本核医学会
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] 新規アストロサイトイメージング薬剤[18F]SMBT-1の有用性2023

    • Author(s)
      田代学, 平岡宏太良, 平岡宏太良, 冨田尚希, 小林良太, TEKEA Berihu, WU Yingying, 原田龍一, 菊地飛鳥, 菊地飛鳥, 武田和子, 草場美津江, 草場美津江, 菊池昭夫, 古川勝敏, 渡部浩司, 渡部浩司, 麦倉俊司, 川勝忍, 石井賢二, 二橋尚志, 加藤隆司, 古本祥三, 岡村信行.
    • Organizer
      日本核医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] Development of a highly sensitive tau tracer 18F-SNFT-1 for imaging early tau pathology in Alzheimer’s disease2023

    • Author(s)
      Okamura N, Harada R, Lerdsirisuk P, Shimizu Y, Yokoyama Y, Du Y, Ezura M, Arai H, Kudo Y, Furumoto S
    • Organizer
      AD/PD2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 新規PETトレーサー[18F]SMBT-1による腫瘍評価可能性の探索2023

    • Author(s)
      阿部未玲、外山由貴、前川由依、齋藤美穂子、高浪健太郎、原田龍一、古本祥三、田代学、高瀬圭.
    • Organizer
      日本医学放射線学会北日本地方会・日本核医学会北日本地方会合同大会
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] 新規PET薬剤[18F]SMBT-1を用いたAD疾患連続体の進行予後予測に関する早期観察結果.2023

    • Author(s)
      田代学, 平岡宏太郎, 平岡宏太郎, 冨田尚希, 石木愛子, TEKEA Berihu, TEKEA Berihu, WU Yingying, 原田龍一, 菊地飛鳥, 菊地飛鳥, 武田和子, 草場美津江, 草場美津江, 菊池昭夫, 古川勝敏, 渡部浩司, 渡部浩司, 麦倉俊司, 小林良太, 川勝忍, 石井賢二, 加藤隆司, 古本祥三,岡村信行.
    • Organizer
      日本認知症学会
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] 新規タウPETトレーサー[18F]SNFT-1の前臨床評価2023

    • Author(s)
      岡村信行,原田龍一,ルーッスィリスック プラディット,清水悠暉,横山裕香,堵怡青,工藤幸司,古本祥三.
    • Organizer
      第44回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-22KK0123
  • [Presentation] 前頭側頭葉変性症における[18F]SMBT-1 PET所見.2023

    • Author(s)
      小林良太, 川勝忍, 森岡大智, 平岡宏太良, 冨田尚希, 四月朔日聖一, MESFIN Berihu, WU Yingying, 武田和子, 草場美津江, 菊池昭夫, 渡部浩司, 麦倉俊司, 古川勝敏, 石井賢二, 加藤隆司, 原田龍一, 古本祥三, 岡村信行, 田代学.
    • Organizer
      日本認知症学会
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] [18F]SMBT-1のHPLC分析条件の最適化.2023

    • Author(s)
      池沼 宏, 木村 泰之, 戸次 雄一, 阿部 潤一郎, 原田 龍一, 岡村 信行, 古本 祥三, 田代 学, 加藤 隆司.
    • Organizer
      日本核医学会
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] Development of a highly sensitive tau tracer 18F-SNFT-1 for imaging early tau pathology in Alzheimer’s disease.2023

    • Author(s)
      Okamura N, Harada R, Lerdsirisuk P, Shimizu Y, Yokoyama Y, Du Y, Ezura M, Arai H, Kudo Y, Furumoto S.
    • Organizer
      AD/PD2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0123
  • [Presentation] Whole-body PET examination with [18F]SMBT-1 to observe physiological distribution of monoamine oxidase B (MAO-B) in humans2022

    • Author(s)
      Tashiro M, Ishioka Y, Mesfin BT, Inamura A,Watanuki S, Miyake M, Hiraoka K, Harada R, Furumoto S, Yanai K, Okamura N, Watabe H.
    • Organizer
      35th Annual Congress of European Association of Nuclear Medicine (EANM2022)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] Physiological uptake of [18F]SMBT-1, a new astrogliosis tracer, in various organs of human body.2022

    • Author(s)
      Tashiro M, Ishioka Y, Mesfin BT, Inamura A,Watanuki S, Miyake M, Hiraoka K, Harada R, Furumoto S, Yanai K, Okamura N, Watabe H.
    • Organizer
      13th Congress of the World Federation of Nuclear Medicine and Biology (WFNMB2022)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] [18F]SNFT-1の結合選択性評価および第二世代タウPET トレーサーとのADタウに対する結合性比較2022

    • Author(s)
      清水悠暉,原田龍一,横山裕香,Pradith Lerdsirisuk,石川洋一,岩田錬,工藤幸司,谷内一彦,岡村信行,古本祥三
    • Organizer
      第5回日本核医学会分科会 放射性薬品科学研究会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 新規PETトレーサー[18F]SMBT-1の全身生理的集積の評価2022

    • Author(s)
      メスフィン・ベリフ、石岡有生、稲村瑛仁、四月朔日聖一、三宅正泰、平岡宏太良、原田龍一、古本祥三、岡村信行、渡部浩司、田代学
    • Organizer
      第42回日本医学放射線学会北日本地方会/日本核医学会北日本地方会[合同開催]
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] 神経病理イメージング剤開発の現状と展望2022

    • Author(s)
      古本祥三
    • Organizer
      第13回世界核医学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 認知症疾患の層別化における[18F]SMBT-1の有用性の検討プロジェクトの経過報告 20222022

    • Author(s)
      田代学, 平岡宏太良, 平岡宏太良, 冨田尚希, 石木愛子, 小林良太, 四月朔日聖一, メスフィン ベリフ, 武田和子, 草場美津江, 菊池昭夫, 渡部浩司, 麦倉俊司, 古川勝敏, 加藤隆司, 石井賢二, 川勝忍, 原田龍一, 古本祥三, 岡村信行.
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] レビー小体型認知症(DLB)剖検脳を用いた神経炎症PETプローブの結合性評価2022

    • Author(s)
      横山裕香, 原田龍一, 石川洋一, 岩田錬, 工藤幸司, 谷内一彦, 村山繁雄, 岡村信行, 古本祥三
    • Organizer
      第23回応用薬理学会シンポジウム
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 反応性アストログリオーシスを定量化する新規画像バイオマーカーの研究開発:認知症疾患の層別化における[18F]SMBT-1の有用性の検討2022

    • Author(s)
      田代学、平岡宏太良、四月朔日聖一、麦倉俊司、冨田尚希、菊池昭夫、古川勝敏、川勝忍、小林良太、渡部浩司、石井賢二、加藤隆司、古本祥三、岡村信行
    • Organizer
      第42回日本医学放射線学会北日本地方会/日本核医学会北日本地方会[合同開催]
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] ヒト剖検脳を用いたTDP-43型前頭側頭葉変性症における[18F]SMBT-1の有用性の検討2022

    • Author(s)
      横山裕香, 原田龍一, 石川洋一, 岩田錬, 工藤幸司, 岩崎靖, 谷内一彦, 岡村信行, 古本祥三
    • Organizer
      第5回日本核医学会分科会 放射性薬品科学研究会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Physiological uptake of [18F]SMBT-1, a new astrogliosis tracer, in whole-body organs2022

    • Author(s)
      Tashiro M, Ishioka Y, Mesfin B, Watanuki S, Hiraoka K, Harada R, Furumoto S, Okamura N, Yanai K, Watabe H
    • Organizer
      13th Congress of the World Federation of Nuclear Medicine and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 神経炎症イメージングのための新規PET薬剤[18F]SMBT-1の動態解析 (Work in Progress)2022

    • Author(s)
      平岡宏太良、メスフィン・ベリフ、石岡有生、四月朔日聖一、石川洋一、船木善仁、稲村瑛仁、原田龍一、石木愛子、古本祥三、岡村信行、渡部浩司、田代学
    • Organizer
      第42回日本医学放射線学会北日本地方会/日本核医学会北日本地方会[合同開催]
    • Data Source
      KAKENHI-PROJECT-23K21420
  • [Presentation] 前頭側頭型変性症で認めるアストロサイト様構造物に対する アミロイド・タウPETプローブの結合性評価2021

    • Author(s)
      横山 裕香,原田 龍一,荒井 啓行,工藤 幸司,古本 祥三,岡村 信行,谷内 一彦
    • Organizer
      第72回 日本薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] オフターゲット結合を示さない 高感度タウPETプローブの開発2021

    • Author(s)
      原田 龍一,Pradith Lerdsirisuk,清水悠暉, 堵怡青,石川洋一, 荒井啓行, 工藤 幸司,谷内 一彦,岩田錬, 古本 祥三,岡村 信行
    • Organizer
      放射性薬品科学研究会2021
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Off-target結合のない新規タウPETプローブの開発2021

    • Author(s)
      清水悠暉, 原田龍一, Pradith Lerdsirisuk, 堵怡青, 工藤幸司, 石川洋一, 岩田錬, 岡村信行, 谷内一彦, 古本祥三
    • Organizer
      第61回日本核医学会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] アストロサイト画像化を目的とした PETプローブ[18F]SMBT-1の代謝特性の検討2021

    • Author(s)
      原田龍一、堵怡青、工藤幸司、岡村信行、 古本祥三、谷内一彦
    • Organizer
      日本分子イメージング学会・第15回総会・学術総会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Amyloid, tau and reactive astrocytosis imaging in aging and Alzheimer’s disease2021

    • Author(s)
      Victor L Villemagne Ryuichi Harada, Vincent Dore, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Samantha Burnham, Natasha Krishnadas, Kun Huang, Kazuhiko Yanai, Christopher C Rowe, and Nobuyuki Okamura
    • Organizer
      ADPD2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 健常者を対象としたPET診断薬18F-SMBT-1の全身臓器における生理的集積の観察2021

    • Author(s)
      石岡 有生、四月朔日 聖一、平岡 宏太良、石川 洋一、船木 善仁、原田 龍一、 岡村 信行、荒井 啓行、古本 祥三、谷内 一彦、渡部 浩司、田代 学
    • Organizer
      第42回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] アミロイド・タウPETプローブのアストロサイト様構造物に対する結合性評価2021

    • Author(s)
      横山 裕香, 原田 龍一, 荒井 啓行, 工藤 幸司, 古本 祥三, 岡村 信行&, 谷内 一彦
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 第二世代タウPETトレーサーの結合性の比較2021

    • Author(s)
      原田 龍一,Pradith Lerdsirisuk,清水悠暉, 堵怡青,石川洋一, 荒井啓行, 工藤 幸司,岩田錬, 谷内 一彦,古本 祥三,岡村 信行
    • Organizer
      第61回日本核医学会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 反応性アストロサイトを標的としたPET プローブ [18F]SMBT-12021

    • Author(s)
      原田龍一, 工藤幸司, 荒井啓行, 田代学, 古本祥三, 岡村信行, 谷内一彦
    • Organizer
      第42回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] ヒト剖検脳に対するMAO-B PETプローブ[18F]SMBT-1の結合2021

    • Author(s)
      原田龍一、堵怡青、横山裕香、古本祥三、工藤幸司、荒井啓行、畠野雄也4 、石原智彦4 、 小野寺理、吉田眞理、北本哲之、岩崎靖、谷内一彦、岡村信行
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 嗜銀顆粒性認知症に対するPETバイオマーカーの探索2021

    • Author(s)
      原田 龍一,堵 恰青, Pradith Lerdsirisuk, 工藤 幸司,古本 祥三,岡村 信行,谷内 一彦
    • Organizer
      第72回 日本薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 分子標的型PETトレーサー開発の現状と展望2021

    • Author(s)
      古本 祥三
    • Organizer
      第42回日本臨床薬理学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03595
  • [Presentation] PHFタウへの感度・特異度に優れた新規タウプローブ[18F]SNFT-1の開発2021

    • Author(s)
      岡村信行、原田龍一、清水悠暉、Pradith Lerdsirisuk、堵怡青、石川洋一、荒井啓行、谷内一彦、工藤幸司、古本祥三
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Preclinical characterization of [18F]THK-5562, a novel tau PET tracer with little off-target binding2020

    • Author(s)
      Harada R, Lerdsirisuk P, Du Y, Ezura M, Shimizu Y, Morito T, Arai H, Yanai K,Kudo Y, Furumoto S, Okamura N
    • Organizer
      HUMAN AMYLOID IMAGING CONFERENCE 2020(マイアミ)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Evaluation of the novel 18F-labeled PET tracer SMBT-1 for imaging astrogliosis in healthy elderly controls and in Alzheimer’s disease2020

    • Author(s)
      Victor L Villemagne Ryuichi Harada, Vincent Dore, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Samantha Burnham, Natasha Krishnadas, Kun Huang, Kazuhiko Yanai, Christopher C Rowe, and Nobuyuki Okamura
    • Organizer
      AAIC2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Development and Identification of [18F]SNFT-1 (THK-5562), a Promising Candidate for Selective Tau PET Tracer in Alzheimer’s Disease2020

    • Author(s)
      Pradith Lerdsirisuk, Ryuichi Haradac, Yuki Shimizub, Yiqing Du, Yoichi Ishikawa, Ren Iwata, Kazuhiko Yanai, Yukitsuka Kudo, Nobuyuki Okamurab, Shozo Furumoto
    • Organizer
      EANM2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] Discovery and evaluation of a novel tau PET tracer [F-18]THK-5562 for Alzheimer's disease2020

    • Author(s)
      Du Y, Harada R, Lerdsirisuk P, Ezura M, Shimizu Y, Morito T, Arai H, Kudo Y, Furumoto S, Yanai K
    • Organizer
      第93回日本薬理学会(横浜)
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 脳内PETイメージングに向けたBBB透過性ペプチド融合affibodyの薬物動態2019

    • Author(s)
      盛戸貴裕、原田龍一、堵 怡青、岩田錬、古本祥三、谷内一彦
    • Organizer
      第70回日本薬理学会北部会(札幌)
    • Data Source
      KAKENHI-PROJECT-19KK0212
  • [Presentation] 汎用的自動合成装置への導入を目指した18F-ホスホニウム型MPIトレーサーの合成法開発2019

    • Author(s)
      安藤與宏、伊東由夏、石川洋一、岩田錬、古本祥三
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03595
  • [Presentation] Fluorine-18 Labeled PET Tracers for Imaging Mitochondria2019

    • Author(s)
      古本祥三
    • Organizer
      3th International Symposium on Molecular Imaging, La Habana, Cuba
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 18F-ホスホニウム型MPIトレーサーの開発と18F-Flurpiridazとの動態比較2018

    • Author(s)
      伊東由夏、冨永隆裕、石川洋一、岩田錬、石渡喜一、古本祥三
    • Organizer
      第58回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] F-18標識PETトレーサー開発の最前線2018

    • Author(s)
      古本祥三
    • Organizer
      In vivoイメージングフォーラム2018
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 心筋血流イメージング剤18F-TAP-31の開発と18F-Flurpiridazとの比較評価2018

    • Author(s)
      冨永隆裕, 秋田諒, 石川洋一, 岩田錬, 石渡喜一, 古本祥三
    • Organizer
      第13回日本分子イメージング学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16H07431
  • [Presentation] New 18F-Labeled PET Tracers for Myocardial Perfusion Imaging2018

    • Author(s)
      古本祥三
    • Organizer
      National Cyclotron and PET Centre Academic Conference 2018, Chulabhorn Graduate Institute, Bangkok
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 心筋血流イメージング剤18F-TAP-31の開発と18F-Flurpiridazとの比較評価2018

    • Author(s)
      冨永隆裕、秋田諒、石川洋一、岩田錬、石渡喜一、古本祥三
    • Organizer
      第13回日本分子イメージング学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 18F標識ホスホニウム型プローブの構造最適化と集積メカニズムの検証2017

    • Author(s)
      冨永 隆裕,秋田 諒,石川 洋一,岩田 錬,石渡 喜一,古本 祥三
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] Development of novel 18F-labeled phosphonium derivatives for mitochondria imaging by positron emission tomography2017

    • Author(s)
      Takahiro Tominaga, Ryo Akita, Yoichi Ishikawa, Ren Iwata, Kiichi Ishiwata, Shozo Furumoto
    • Organizer
      22st International Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 18F標識ホスホニウム型プローブの構造最適化と集積メカニズムの検証2017

    • Author(s)
      冨永隆裕, 秋田諒, 石川洋一, 岩田錬, 石渡喜一, 古本祥三
    • Organizer
      第57回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H07431
  • [Presentation] 大脳皮質基底核症候群における18F-THK5351 PETの経時的変化2017

    • Author(s)
      菊池昭夫、江面道典、岡村信行、長谷川隆文、石木愛子、原田龍一、荒井啓行、谷内一彦、古本 祥三、田代 学、工藤幸司、武田 篤、青木正志
    • Organizer
      第36回日本認知症学会
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] Novel 18F-labeled triarylphosphonium derivatives for mitochondria imaging2017

    • Author(s)
      S. Furumoto, T. Tominaga, R. Akita, A. Kazama, Y. Ishikawa, R., Iwata, K. Ishiwata
    • Organizer
      30th Annual EANM Congress of the European Association of Nuclear Medicine 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 基礎研究におけるPET薬剤の生物学的評価手法2017

    • Author(s)
      古本 祥三
    • Organizer
      第57回日本核医学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] 18F-THK5351 PET in corticobasal syndrome2017

    • Author(s)
      Kikuchi A, Okamura N, Hasegawa T, Ezura M, Baba T, Sugeno N, Yoshida S, Kobayashi J, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] Development of novel 18F-labeled phosphonium derivatives for mitochondria imaging by positron emission tomography2017

    • Author(s)
      Takahiro Tominaga, Ryo Akita, Yoichi Ishikawa, Ren Iwata, Kiichi Ishiwata, Shozo Furumoto
    • Organizer
      The 22nd International Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07431
  • [Presentation] Novel 18F-labeled triarylphosphonium derivatives for mitochondria imaging2017

    • Author(s)
      Shozo Furumoto, Takahiro Tominaga, Ryo Akita, Azusa Kazama, Yoichi Ishikawa, Ren Iwata, Kiichi Ishiwata
    • Organizer
      EANM'17 Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07431
  • [Presentation] ミトコンドリアを標的とした新規 18F標識ホスホニウム型プローブの開発2016

    • Author(s)
      冨永 隆裕, 風間 あずさ, 石川 洋一, 岩田 錬, 石渡 喜一, 古本 祥三
    • Organizer
      第56回 日本核医学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16K10267
  • [Presentation] Assessment of tau pathology in patients with corticobasal syndrome using 18F-THK5351 PET2016

    • Author(s)
      Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Toru Baba, Naoto Sugeno, Ryuji Oshima, Shun Yoshida, Junpei Kobayashi, Ezura M, Kobayashi M, Tano O, Mugikura S, Iwata R, Ishiki A, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
    • Organizer
      The Movement Disorder Society's 20th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] 無細胞タンパク質合成系を利用したHER2イメージング剤の合成と評価2016

    • Author(s)
      阿部 優樹, 古本 祥三, 岩田 錬, 石川 洋一, 木川 隆則, 樋口 佳恵, 横山 順
    • Organizer
      第56回 日本核医学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16K10267
  • [Presentation] フッ素18標識心筋イメージング剤の開発2016

    • Author(s)
      古本祥三
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] Design of a diabody-based IgG-like bispecific antibody with higher antitumor activity, degradation resistance, and long half-life2016

    • Author(s)
      Asano R., Shimomura I., Konno S., Furumoto S., Umetsu M., Kumagai I.
    • Organizer
      The 29th Annual and International Meeting of Japanese Association for Animal Cell Technolog
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04306
  • [Presentation] ミトコンドリアを標的とした新規18F標識ホスホニウム型プローブの開発2016

    • Author(s)
      冨永隆裕、風間あずさ、石川洋一、岩田錬、石渡喜一、古本祥三
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16H05386
  • [Presentation] パーキンソン病患者での[11C]BF-227 PETによるα-シヌクレイン蛋白凝集体の画像化2016

    • Author(s)
      菊池昭夫、岡村信行、馬場 徹、長谷川隆文、菅野直人、大嶋龍司、吉田隼、小林潤平、平岡宏太良、古本祥三、谷内一彦、田代 学、工藤幸司、武田 篤、青木正志
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸、神戸コンベンションセンター・神戸ポートピアホテル
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] 2-アリールキノリン PET タウイメージング剤の構造活性相関研究2015

    • Author(s)
      多胡哲郎,古本祥三,岡村信行,原田龍一,石川洋一,谷内一彦,岩田錬,工藤幸司
    • Organizer
      日本分子イメージング学会第 10 回総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] がん細胞成長阻害活性を有する四量体化抗EGFR一本鎖抗体の機能評価2015

    • Author(s)
      浅野竜太郎, 小山典明, 萩原康世, 安中宏彰, 鉞 陽介, 古本祥三, 荒井杏子, 尾形裕未, 梅津光央, 熊谷 泉
    • Organizer
      GE Life Sciences Day 2015
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-07-24
    • Data Source
      KAKENHI-PROJECT-15H04306
  • [Presentation] [11C]BF-227 PETにおける多系統萎縮症脳内α-シヌクレインの経時的変化2015

    • Author(s)
      菊池昭夫、岡村信行、馬場 徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、吉田隼、古本祥三、平岡宏太良、谷内一彦、田代 学、工藤幸司、糸山泰人、武田 篤、青木正志.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ (新潟)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] PETによるアルツハイマー病タウイメージングのための2-アリールキノリン誘導体開発2015

    • Author(s)
      多胡哲郎,古本祥三,岡村信行,原田龍一,安立創,石川洋一,谷内一彦,工藤幸司,岩田錬
    • Organizer
      第 55 回日本核医学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] Longitudinal [11C]BF-227 PET study in MSA-C patients2015

    • Author(s)
      Kikuchi A, Okamura N, Tashiro M, Furumoto S, Hasegawa T, Watanuki S, Hiraoka K, Funaki Y, Kobayashi M, Sugeno N, Baba T, Konno M, Miura E, Oshima R, Yoshida S, Iwata R, Takahashi S, Fukuda H, Itoyama Y, Arai H, Kudo Y, Yanai K, Aoki M, Takeda A.
    • Organizer
      19th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-06-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] タウイメージングトレーサー[18F]THK-5351 の代謝解析2015

    • Author(s)
      原田龍一,岡村信行,古本祥三,多胡哲郎,岩田錬,谷内一彦,工藤幸司
    • Organizer
      第 55 回日本核医学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] PETプローブの創製研究 ~分子設計から橋渡し研究まで~2015

    • Author(s)
      古本祥三
    • Organizer
      平成27年度日本薬学会東北支部総会・学術講演会
    • Place of Presentation
      仙台
    • Year and Date
      2015-06-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] Preclinical characterization of [18F]THK-5117 enantiomers as a PET tau probe for tau pathology in Alzheimer’s disease2015

    • Author(s)
      T. Tago, S. Furumoto, N. Okamura, R. Harada, H. Adachi, Y. Ishikawa, K. Yanai, R. Iwata, Y. Kudo.
    • Organizer
      21st International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      Columbia, Missouri
    • Year and Date
      2015-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] アルツハイマー病患者における[18F]THK5105の臨床評価2013

    • Author(s)
      岡村信行、古本祥三、原田龍一、多胡哲朗、谷内一彦、レイチェルマリガン、クリストファーロウ、ビクタービルマーニ
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] PET用タウイメージング剤[18F]THK5105のエナンチオマー体の合成と評価2013

    • Author(s)
      多胡哲朗、古本祥三、岡村信行、原田龍一、石川洋一、谷内一彦、工藤幸司、岩田錬
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] 無細胞蛋白質合成系を用いた^<11>C標識一本鎖抗体の合成2012

    • Author(s)
      伊藤悠一、古本祥三、松田貴意、樋口佳恵、横山順、張明栄、谷内一彦、岩田錬、木川隆則
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-23791387
  • [Presentation] PETイメージングによる薬物動態と薬効の評価2012

    • Author(s)
      古本祥三,谷内一彦
    • Organizer
      第28回日本DDS学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Presentation] PETイメージングによる薬物動態と薬効の評価2012

    • Author(s)
      古本祥三、谷内一彦
    • Organizer
      第28回日本DDS学会
    • Place of Presentation
      札幌市
    • Invited
    • Data Source
      KAKENHI-PROJECT-23791387
  • [Presentation] Bevacizumab increases anaerobic glycolysis on tumor2012

    • Author(s)
      Yoshioka T, Furumoto S., and Fukuda H
    • Organizer
      The 2012 SNM Annual Meeting
    • Place of Presentation
      マイアミ,USA
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Presentation] ^<18>F-フロロデオキシマンノースの腫瘍イメージング剤としての特性評価2011

    • Author(s)
      古本祥三,新保亮,石川洋一,谷内一彦,岩田錬,福田寛
    • Organizer
      第51回日本核医学会学術総会
    • Place of Presentation
      つくば
    • Year and Date
      2011-10-28
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Presentation] Characterization of 2-[^<18>F]fluoro-2-deoxy-D-mannose([^<18>F]FDM) as a tumor imaging agent2011

    • Author(s)
      Shozo Furumoto, Ryo Shinbo, Youichi Ishikawa, Kazuhiko Yanai, Ren Iwata, Hiroshi Fukuda
    • Organizer
      19th Int. Symp. Radioparm. Sciences
    • Place of Presentation
      オランダ・アムステ ルダム
    • Year and Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Presentation] Characterization of 2-[^<18>F]fluoro-2-deoxy-D-mannose([^<18>F]FDM) as a tumor imaging agent2011

    • Author(s)
      Furumoto S., Ryo Shinbo, Youichi Ishikawa, Kazuhiko Yanai, Ren Iwata, Fukuda H.
    • Organizer
      the 19th International Symposium on Radiopharmaceutical Sciences 2011
    • Place of Presentation
      アムステルダム,オランダ
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Presentation] A customized automated microfluidic platform for radiosynthesis of multiple ^<18>F PET compounds using electrochemicallyconcentrated [^<18>F]fluoride2011

    • Author(s)
      Rebecca Wong, Ren Iwata, Hidekazu Saiki, Shozo Furumoto, Yoichi Ishikawa, Eiichi Ozeki
    • Organizer
      19th Int. Symp. Radioparm. Sciences
    • Place of Presentation
      オランダ・アムステルダム
    • Year and Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Presentation] A customized automated microfluidic platform for radiosynthesis of multiple ^<18>F PET compounds using electrochemically concentrated [^<18>F]fluoride2011

    • Author(s)
      Rebecca Wong, Ren Iwata, Hidekazu Saiki, Shozo Furumoto Yoichi, Ishikawa, Eiichi Ozeki
    • Organizer
      19th Int.Symp.Radioparm.Sciences
    • Place of Presentation
      オランダ・アムステルダム
    • Year and Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22390228
  • [Presentation] Characterization of 2-[18F]fluoro-2-deoxy-D-mannose ([18F]FDM) as a tumor imaging agent2011

    • Author(s)
      Shoso Furumoto, Ryo Shinbo, Youichi Ishikawa, Kazuhiko Yanai, Ren Iwata, Hiroshi Fukuda
    • Organizer
      19th International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      VU University Medical Center
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Presentation] 18F-フロロデオキシマンノースの腫瘍イメージング剤としての特性評価2011

    • Author(s)
      古本祥三、新保亮、石川洋一、谷内一彦、岩田錬、福田寛
    • Organizer
      第51回日本核医学会学術総会
    • Place of Presentation
      つくば国際会議場
    • Data Source
      KAKENHI-PROJECT-23650610
  • [Presentation] Synthesis and preliminary evaluation of [18F]FDM for tumor imaging.2009

    • Author(s)
      Furumoto S, et al
    • Organizer
      18th Int.Symp.Radiopharm.Sci.
    • Place of Presentation
      Edomonton
    • Year and Date
      2009-07-13
    • Data Source
      KAKENHI-PROJECT-20591433
  • [Presentation] Synthesis and preliminary evaluation of [^<18>F]FDM for tumor imaging2009

    • Author(s)
      古本祥三, 福田寛, 6人, 6番目
    • Organizer
      ^<18>th Int Symp Radiopharm Sci
    • Place of Presentation
      Edmonton, Canada
    • Data Source
      KAKENHI-PROJECT-19390312
  • [Presentation] 2-フロロピリジン誘導体化による代謝安定性の向上を目指した^<18>F標識MMP-2画像化プローブの開発2009

    • Author(s)
      古本祥三, 岩田錬, 福田寛, (6人, 5,6番目)
    • Organizer
      第49回日本核医学会学術総会
    • Place of Presentation
      旭川
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-19390312
  • [Presentation] Synthesis and preliminary evaluation of [^<18>F] FDM for tumor imaging2009

    • Author(s)
      Furumoto S, Iwata R, Fukuda H(6人, 5,6番目)
    • Organizer
      18^<th> Int Symp Radiopharm Sci
    • Place of Presentation
      Edmonton, Canada
    • Data Source
      KAKENHI-PROJECT-19390312
  • [Presentation] Assessement of hypoxia induced by vascular targeting therapy2007

    • Author(s)
      Furumoto S, Iwata R, Fukuda H(10人, 8, 10番目)
    • Organizer
      54^<th> SNM Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-19390312
  • [Presentation] 血管標的薬剤AVE8062により誘発される腫瘍低酸素状態の評価2007

    • Author(s)
      古本祥三、本田芳雄、堀勝義、石川洋一、工藤幸司、岩田錬
    • Organizer
      第47回日本核医学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Presentation] Assessment of tumor hypoxia induced by vascular targeting therapy.2007

    • Author(s)
      Furumoto S
    • Organizer
      54th SNM Annual Meeting
    • Place of Presentation
      ワシントンDC, USA
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-19390312
  • [Presentation] マトリックスメタロブロテアーゼ-2のイメージングを目指したPET用標識薬剤の開発2007

    • Author(s)
      古本祥三、渋間祐太朗、金田朋洋、石川洋一、工藤幸司、岩田錬
    • Organizer
      第47回日本核医学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Presentation] マトリックスメタロプロテアーゼー2のイメージングを目指したPET用標識薬剤の開発2007

    • Author(s)
      古本祥三, 他
    • Organizer
      第47回日本核医学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Presentation] Assessment of tumor hypoxia induced by vascular targeting therapy.2007

    • Author(s)
      S. Furumoto, Hori K, Honda Y, Yoshioka T, Yamaura G, Ishikawa Y, Kubota K, Fukuda H, Kudo Y, Iwata R
    • Organizer
      The 54th Society of Nuclear Medicine Annual Meeting
    • Place of Presentation
      Washington DC (USA)
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-19790853
  • [Presentation] パーキンソン病における脳内α-シヌクレイン蛋白凝集体のPETによる画像化.

    • Author(s)
      菊池昭夫、馬場 徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、岡村信行、古本祥三、谷内一彦、田代 学、工藤幸司、糸山泰人、武田 篤、青木正志.
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] パーキンソン病における脳内α-シヌクレイン蛋白凝集体のPETによる画像化.

    • Author(s)
      菊池昭夫、馬場 徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、岡村信行、古本祥三、谷内一彦、田代 学、工藤幸司、糸山泰人、武田 篤、青木正志.
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] In vivo selective imaging of tau pathology in Alzheimer's disease with 18F-THK5117

    • Author(s)
      Okamura N, Furumoto S, Harada R, Furukawa K, Ishiki A, Iwata R, Tashiro M, Yanai K, Arai H, Kudo Y.
    • Organizer
      Society of Nuclear Medicine and Molecular Imaging 2014
    • Place of Presentation
      米国セントルイス
    • Year and Date
      2014-06-07 – 2014-06-11
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] PET用タウイメージング剤[18F]THK-5105エナンチオマー体の評価

    • Author(s)
      多胡 哲郎, 古本 祥三, 岡村 信行, 原田 龍一, 安立 創, 石川 洋一, 谷内 一彦, 工藤 幸司, 岩田 錬
    • Organizer
      第9回日本分子イメージング学会総会・学術集会
    • Place of Presentation
      大阪千里
    • Year and Date
      2014-05-22 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] [11C] BF-227 PET can visualize in vivo α-synuclein deposition in Parkinson’s disease.

    • Author(s)
      Kikuchi A, Okamura N, Tashiro M, Hasegawa T, Sugeno N, Baba T, Konno M, Miura E, Oshima R, Furumoto S, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Aoki M, Itoyama Y, Takeda A.
    • Organizer
      18th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] 無細胞蛋白質合成系を用いた11C標識一本鎖抗体の合成

    • Author(s)
      伊藤悠一、古本祥三、松田貴意、樋口佳恵、 横山順、張明栄、谷内一彦、岩田錬、木川隆則
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23791387
  • [Presentation] Chirality of [18F]THK-5105 Affects its Preclinical Characteristics as a PET Tau Imaging Probe

    • Author(s)
      Tago T, Furumoto S, Okamura N, Harada R, Adachi H, Ishikawa Y, Yanai K, Iwata R, Kudo Y
    • Organizer
      9th Human Amyloid Imaging 2015
    • Place of Presentation
      米国マイアミ
    • Year and Date
      2015-01-14 – 2015-01-16
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] PET用タウイメージング剤[18F]THK-5105のエナンチオマー体の詳細評価

    • Author(s)
      多胡 哲郎, 古本 祥三, 岡村 信行, 原田 龍一, 安立 創, 石川 洋一, 谷内 一彦, 工藤 幸司, 岩田 錬
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] [11C] BF-227 PET can visualize in vivo α-synuclein deposition in Parkinson’s disease.

    • Author(s)
      Kikuchi A, Okamura N, Tashiro M, Hasegawa T, Sugeno N, Baba T, Konno M, Miura E, Oshima R, Furumoto S, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Aoki M, Itoyama Y, Takeda A.
    • Organizer
      18th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] Accumulation of the novel tau imaging tracer, 18F-5117 is associated with brain atrophy in Alzheimer's disease.

    • Author(s)
      Ishiki A, Furumoto S, Harada R, Furukawa K, Okamura N, Tashiro M, Yanai K, Kudo Y, Arai H
    • Organizer
      Alzheimer's Association International Conference 2014
    • Place of Presentation
      コペンハーゲン
    • Year and Date
      2014-07-12 – 2014-07-17
    • Data Source
      KAKENHI-PROJECT-25293259
  • [Presentation] Tau Probe Development: From A Molecular Design To A Clinical Research.

    • Author(s)
      Furumoto S., Okamura N., Kudo Y.
    • Organizer
      第9回日本分子イメージング学会総会・学術集会
    • Place of Presentation
      大阪千里
    • Year and Date
      2014-05-22 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-25293259
  • 1.  OKAMURA Nobuyuki (40361076)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 55 results
  • 2.  IWATA Ren (60143038)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 28 results
  • 3.  原田 龍一 (60735455)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 43 results
  • 4.  FUKUDA Hiroshi (30125645)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 5.  KIKUCHI Akio (80463785)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 6.  TASHIRO Manabu (00333477)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 23 results
  • 7.  SHIDAHARA Miho (20443070)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 8.  渡部 浩司 (40280820)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 9.  YOSHIOKA Takashi (90271981)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  Yanai Kazuhiko (50192787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 23 results
  • 11.  TAKAHASHI Kazuhiro (20370257)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 12.  SAIKI Hidekazu (70466382)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 13.  TAKEDA Atsushi (70261534)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 14.  FUNAKI Yoshihito (50261491)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 15.  Tominaga Takahiro (50778602)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 16.  Narumi Harada (70547413)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 17.  原田 愛子 (30778634)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 28 results
  • 18.  高浪 健太郎 (90447160)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 19.  石田 孝宣 (00292318)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 20.  鈴木 貴 (10261629)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 21.  高瀬 圭 (60361094)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 22.  金田 朋洋 (50323019)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  OZEKI Eiichi (30192529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 24.  TERAKAWA Atsuki (10250854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  ISHII Keizo (00134065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KIKUCHI Yohei (50359535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  MATSUYAMA Shigeo (70219525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  SAKEMI Yasuhiro (90251602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  Asano Ryutaro (80323103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 30.  ISHIKAWA Yoichi (60361200)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 31.  TERASAKI Kazunori (60285632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  Masamune Atsushi (90312579)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  高井 良尋 (50107653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  工藤 幸司 (80375203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  仲田 栄子 (60375201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  渡邉 建彦 (70028356)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  櫻井 映子 (90153949)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  山崎 浩道 (00166654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  真壁 幸樹 (20508072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  吉川 雄朗 (70506633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  進藤 智彦 (80781294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 42.  濱田 晋 (20451560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  茨木 正信 (40360359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  江幡 明子 (90636010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  藤本 敏彦 (00229048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 46.  外山 由貴 (30770862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 47.  平岡 宏太良 (70586049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 48.  瀧 靖之 (10375115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  領家 梨恵 (10737464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  米田 哲也 (20305022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  舘脇 康子 (40722202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  関根 弘樹 (50506285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  中瀬 泰然 (60390928)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  山崎 有人 (70833367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  手塚 雄太 (50854642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  WONGSO HENDRIS
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  古川 勝敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 58.  青木 正志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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